연구성과로 돌아가기
2020 연구성과 (155 / 270)
※ 컨트롤 + 클릭으로 열별 다중 정렬 가능합니다.
Excel 다운로드
| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ○ | ○ | Article | Size-dependent magnetic and magnetothermal properties of gadolinium silicide nanoparticles | Gadolinium silicide (Gd5Si4) nanoparticles are an interesting class of materials due to their high magnetization, low Curie temperature, low toxicity in biological environments and their multifunctional properties. We report the magnetic and magnetothermal properties of gadolinium silicide (Gd5Si4) nanoparticles prepared by surfactant-assisted ball milling of arc melted bulk ingots of the compound. Using different milling times and speeds, a wide range of crystallite sizes (13-43 nm) could be produced and a reduction in Curie temperature (T-C) from 340 K to 317 K was achieved, making these nanoparticles suitable for self-controlled magnetic hyperthermia applications. The magnetothermal effect was measured in applied AC magnetic fields of amplitude 164-239 Oe and frequencies 163-519 kHz. All particles showed magnetic heating with a strong dependence of the specific absorption rate (SAR) on the average crystallite size. The highest SAR of 3.7 W g(-1)was measured for 43 nm sized nanoparticles of Gd5Si4. The high SAR and lowT(C), (within the therapeutic range for magnetothermal therapy) makes the Gd(5)Si(4)behave like self-regulating heat switches that would be suitable for self-controlled magnetic hyperthermia applications after biocompatibility and cytotoxicity tests. | Nauman, Muhammad; Alnasir, Muhammad Hisham; Hamayun, Muhammad Asif; Wang, YiXu; Shatruk, Michael; Manzoor, Sadia | Kyungpook Natl Univ, Dept Phys, Daegu 41566, South Korea; COMSATS Univ Islamabad, Dept Phys, Islamabad 45550, Pakistan; Florida State Univ, Dept Chem & Biochem, Tallahassee, FL 32306 USA; Univ Sci & Technol Beijing, Sch Mat Sci & Engn, Beijing 100083, Peoples R China | ; Alnasir, Muhammad/LIG-2857-2024; Nauman, Muhammad/AAG-9189-2019; Manzoor, Sadia/LFR-8608-2024; Shatruk, Michael/AFH-5616-2022 | 57195713298; 57196039190; 57220043072; 57192184069; 6603333408; 7004376392 | nouman.kakakhail@gmail.com;sadia_manzoor@comsats.edu.pk; | RSC ADVANCES | RSC ADV | 2046-2069 | 10 | 47 | SCIE | CHEMISTRY, MULTIDISCIPLINARY | 2020 | 3.361 | 45.2 | 0.61 | 2025-06-25 | 15 | 14 | ABSORPTION RATE; HYPERTHERMIA; CANCER | Ball milling; Biocompatibility; Crystallite size; Curie temperature; Gadolinium; Gadolinium compounds; Hyperthermia therapy; Metal castings; Milling (machining); Nanoparticles; Silicides; Silicon; Biological environments; Low Curie temperature; Magnetic hyperthermia; Magnetothermal effect; Magnetothermal properties; Multifunctional properties; Specific absorption rate; Surfactant assisted; Nanomagnetics | English | 2020 | 2020-07-30 | 10.1039/d0ra05394e | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Stereoselective polymerization of methyl methacrylate and rac-lactide mediated by iminomethylpyridine based Cu(ii) complexes | Iminomethylpyridine based copper(ii) complexes [LnCuCl2] (L-n = L-A, L-C-L-F) and [LBCu(mu-Cl)Cl](2) have been synthesized and characterized. [LCCuCl2] and [LECuCl2] were identified to possess distorted square pyramidal geometries obtained via N,N '-bidentate coordination, whereas [LFCuCl2] showed N,N ',N ''-coordination of the corresponding ligand (L-F). [LBCu(mu-Cl)Cl](2) was found to be dimeric with a distorted square pyramidal geometry around the Cu(ii) center. The catalytic properties of dimethyl derivatives, generated in situ, towards the ring opening polymerization (ROP) of rac-LA were investigated. All the complexes efficiently polymerized rac-LA and yielded heterotactic poly(lactide) (PLA) (P-r up to 0.88 at -25 degrees C). Further, these complexes could effectively polymerize methyl methacrylate (MMA) at 60 degrees C in the presence of modified methylaluminoxane (MMAO), to furnish syndio-enriched PMMA. The catalytic efficacies of synthesized complexes can be correlated to the suitable complexity of the substituents attached to the ligand architecture. Thus, both the steric and electronic properties as well as the orientation of the various substituents relative to the xy plane of the pyridyl moiety and metal center play an influential role in steering catalytic activities, whereas the selectivities remain unaffected. | Lee, Jaegyeong; Yoon, Minyoung; Lee, Hyosun; Nayab, Saira | Kyungpook Natl Univ, Green Nano Mat Res Ctr, Dept Chem, 80 Daehakro, Daegu 41566, South Korea; Shaheed Benazir Bhutto Univ, Dept Chem, Sheringal Dir U, Khyber Pakhtunk, Pakistan | Nayab, Saira/JBS-3013-2023 | 57202254509; 25222186500; 15750846000; 36490286400 | hyosunlee@knu.ac.kr;drnayab@sbbu.edu.pk; | RSC ADVANCES | RSC ADV | 2046-2069 | 10 | 27 | SCIE | CHEMISTRY, MULTIDISCIPLINARY | 2020 | 3.361 | 45.2 | 0.73 | 2025-06-25 | 16 | 17 | RING-OPENING POLYMERIZATION; N-SUBSTITUTED 2-IMINOMETHYLPYRIDINE; SCHIFF-BASE; ZINC(II) COMPLEXES; COBALT(II) COMPLEXES; METAL-COMPLEXES; STRUCTURAL-CHARACTERIZATION; ANTIMICROBIAL ACTIVITY; COPPER(I) COMPLEXES; BIOLOGICAL-ACTIVITY | Acrylic monomers; Catalyst activity; Electronic properties; Esters; Ligands; Ring opening polymerization; Synthesis (chemical); Bidentate coordination; Catalytic properties; Copper complexes; Ligand architecture; Methyl methacrylates; Modified methylaluminoxane; Square-pyramidal geometry; Stereoselective polymerization; Copper compounds | English | 2020 | 2020-04-22 | 10.1039/d0ra00805b | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | The linkers in fluorene-labeled 2′-deoxyuridines affect fluorescence discriminating phenomena upon duplex formation | Three fluorene-labeled 2 '-deoxyuridines that differ in terms of their linkers-U-F (without linker), U-FL (with ethynyl linker), and U-DF (with diethynyl linker)-have been introduced at the central positions of oligodeoxynucleotides to examine the effects that their linkers have on the fluorescence emission properties upon duplex formation with fully matched and single-base-mismatched targets. Here, we describe the influence of the linkers on the emission behavior, the intramolecular electron transfer between the fluorene moiety and the uracil base after photoexcitation, and the structural stability upon duplex formation. The probe containing the U-FL residue (with an ethynyl linker) and cytosine residues as flanking bases exhibited the greatest fluorescence turn-on selective behavior toward the perfectly matched target. | Lee, So Young; Hong, Seung Woo; Yeo, Hyeonuk; Hwang, Gil Tae | Kyungpook Natl Univ, Dept Chem, Daegu 41566, South Korea; Kyungpook Natl Univ, Green Nano Mat Res Ctr, Daegu 41566, South Korea; Kyungpook Natl Univ, Dept Chem Educ, Daegu 41566, South Korea | Yeo, Hyeonuk/AHE-0397-2022; yeo, hyeonuk/G-7890-2017; Hwang, Gil Tae/L-6502-2017 | 57217014654; 57200270416; 55324816500; 7202676087 | yeo@knu.ac.kr;giltae@knu.ac.kr; | RSC ADVANCES | RSC ADV | 2046-2069 | 10 | 32 | SCIE | CHEMISTRY, MULTIDISCIPLINARY | 2020 | 3.361 | 45.2 | 0.06 | 2025-06-25 | 1 | 1 | FREE MOLECULAR BEACON; SINGLE-NUCLEOTIDE; ELECTRON-TRANSFER; DNA; OLIGONUCLEOTIDES; HYBRIDIZATION; SYSTEMS; PROBES; NUCLEOSIDES; FLUOROPHORE | Stability; Duplex formation; Emission behavior; Fluorene moiety; Fluorescence emission; Intra-molecular electron transfer; Oligodeoxynucleotides; Perfectly matched; Structural stabilities; Fluorescence | English | 2020 | 2020-05-18 | 10.1039/d0ra01651a | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Thermotolerance effect of plant growth-promotingBacillus cereusSA1 on soybean during heat stress | Background Incidences of heat stress due to the changing global climate can negatively affect the growth and yield of temperature-sensitive crops such as soybean variety, Pungsannamul. Increased temperatures decrease crop productivity by affecting biochemical, physiological, molecular, and morphological factors either individually or in combination with other abiotic stresses. The application of plant growth-promoting endophytic bacteria (PGPEB) offers an ecofriendly approach for improving agriculture crop production and counteracting the negative effects of heat stress. Results We isolated, screened and identified thermotolerantB. cereusSA1 as a bacterium that could produce biologically active metabolites, such as gibberellin, indole-3-acetic acid, and organic acids. SA1 inoculation improved the biomass, chlorophyll content, and chlorophyll fluorescence of soybean plants under normal and heat stress conditions for 5 and 10 days. Heat stress increased abscisic acid (ABA) and reduced salicylic acid (SA); however, SA1 inoculation markedly reduced ABA and increased SA. Antioxidant analysis results showed that SA1 increased the ascorbic acid peroxidase, superoxide dismutase, and glutathione contents in soybean plants. In addition, heat stress markedly decreased amino acid contents; however, they were increased with SA1 inoculation. Heat stress for 5 days increased heat shock protein (HSP) expression, and a decrease inGmHSPexpression was observed after 10 days; however, SA1 inoculation augmented the heat stress response and increased HSP expression. The stress-responsiveGmLAX3andGmAKT2were overexpressed in SA1-inoculated plants and may be associated with decreased reactive oxygen species generation, altered auxin and ABA stimuli, and enhanced potassium gradients, which are critical in plants under heat stress. Conclusion The current findings suggest thatB. cereusSA1 could be used as a thermotolerant bacterium for the mitigation of heat stress damage in soybean plants and could be commercialized as a biofertilizer only in case found non-pathogenic. | Khan, Muhammad Aaqil; Asaf, Sajjad; Khan, Abdul Latif; Jan, Rahmatullah; Kang, Sang-Mo; Kim, Kyung-Min; Lee, In-Jung | Kyungpook Natl Univ, Sch Appl Biosci, Daegu 41566, South Korea; Univ Nizwa, Nat & Med Sci Res Ctr, Nizwa 616, Oman | ; Asaf, Sajjad/ABA-3647-2021; Lee, In-Jung/GLS-0432-2022; Kim, Kyung-Min Kim/C-7007-2014; Jan, Rahmatullah/AIC-3439-2022; Khan, Abdul/B-1005-2010; Kang, Sang-Mo/MBG-7823-2025; Khan, Muhammad/ABB-9797-2021 | 57188585606; 56595059900; 26639372800; 57201981969; 56189696900; 34868260300; 16425830900 | ijlee@knu.ac.kr; | BMC MICROBIOLOGY | BMC MICROBIOL | 1471-2180 | 20 | 1 | SCIE | MICROBIOLOGY | 2020 | 3.605 | 45.2 | 7.88 | 2025-06-25 | 164 | 212 | B; cereusSA1; Heat stress; Phytohormone; Amino acid; HSP expression; Soybean | PHOSPHATE-SOLUBILIZING BACTERIA; GROWTH-PROMOTING RHIZOBACTERIUM; ENTEROBACTER-LUDWIGII GAK2; INDOLE ACETIC-ACID; SALICYLIC-ACID; SALT STRESS; MOLECULAR-MECHANISMS; ANTIOXIDANT SYSTEMS; GIBBERELLIC-ACID; CLIMATE-CHANGE | Amino acid; B. cereus SA1; Heat stress; HSP expression; Phytohormone; Soybean | Abscisic Acid; Bacillus cereus; Crops, Agricultural; Endophytes; Gene Expression Regulation, Plant; Heat-Shock Proteins; Heat-Shock Response; Plant Proteins; Salicylic Acid; Soil Microbiology; Soybeans; Thermotolerance; abscisic acid; carboxylic acid; gibberellin; glutathione; heat shock protein; indoleacetic acid; peroxidase; phytohormone; potassium; reactive oxygen metabolite; superoxide dismutase; heat shock protein; plant protein; salicylic acid; amino acid synthesis; antioxidant assay; Article; Bacillus cereus; bacterial strain; bacterium isolation; biomass; chlorophyll content; chlorophyll fluorescence; controlled study; GmAKT2 gene; GmHSP gene; GmLAX3 gene; heat stress; heat tolerance; in vitro study; mass fragmentography; nonhuman; plant gene; plant growth; protein expression; soybean; Bacillus cereus; crop; drug effect; endophyte; gene expression regulation; genetics; growth, development and aging; heat shock response; heat tolerance; isolation and purification; metabolism; microbiology; physiology; soybean | English | 2020 | 2020-06-22 | 10.1186/s12866-020-01822-7 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Two-dimensional square-grid iron(ii) coordination polymers showing anion-dependent spin crossover behavior | Two Fe(ii)-based coordination polymers [Fe(tpmd)(2)(NCS)(2)]5.5H(2)O (1) and [Fe(tpmd)(2)(NCSe)(2)]7H(2)O (2) with the framework of square-grid type have been assembled from FeSO(4)7H(2)O, N,N,N ',N '-tetrakis(pyridin-4-yl)methanediamine (tpmd), and KNCS/KNCSe in methanol and characterized. By utilizing two pyridine groups of a tpmd ligand, 1 and 2 are formed in two-dimensional layered structures through coordination of octahedral iron(ii) ions with the tpmd to NCS-/NCSe- ligands in which they have a supramolecular isomorphous conformation. 1 shows a paramagnetic behavior between 2 and 300 K, while 2 exhibits two-step spin crossover (ca. 145 and 50 K) in the temperature range due to the coordination of NCSe- ligands. At 300 K 2 is fully high-spin state. However, at 100 K 2 becomes ca. 50% high spin and 50% low spin iron(ii) ions, which is verified by magnetic moments. In the structural analysis of 2 at 100 K, two different layers are observed with different bond distances around iron(ii) ions in which the layers are stacked alternately. | Shin, Jong Won; Jeong, Ah Rim; Jeong, Jong Hwa; Zenno, Hikaru; Hayami, Shinya; Min, Kit Sik | Kyungpook Natl Univ, Dept Chem, Daegu 41566, South Korea; Kumamoto Univ, Dept Chem, Kumamoto 8608555, Japan; Kyungpook Natl Univ, Dept Chem Educ, Daegu 41566, South Korea | Hayami, Shinya/E-7019-2014; Hayami, Shinya/Y-3354-2019 | 35314133900; 56014521800; 7402045988; 57209749458; 7006400078; 7201466885 | jeongjh@knu.ac.kr;minks@knu.ac.kr; | RSC ADVANCES | RSC ADV | 2046-2069 | 10 | 9 | SCIE | CHEMISTRY, MULTIDISCIPLINARY | 2020 | 3.361 | 45.2 | 0.24 | 2025-06-25 | 7 | 7 | COMPLEX; LIGAND; COMPOUND; SE; HYSTERESIS; FRAMEWORKS; FAMILY; SERIES; PHASE | Ions; Ligands; Magnetic moments; Polymers; Bond distance; Coordination Polymers; Different layers; High spin state; Paramagnetic behavior; Spin crossovers; Temperature range; Two-dimensional layered structures; Iron compounds | English | 2020 | 2020-02-02 | 10.1039/c9ra09782a | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | Article | Utilization of 2N + 1 Units for 2-DOF Discrete Bending Joint to Transmit Perfect Axial Rotation for Laparoscopic Instruments | Laparoscopic instruments, which have traditionally been long and straight, have been equipped with wrist joints for executing complex procedures. Among the many methods for constructing a cable-driven wrist joint for such instruments, the use of pulleyless rolling unit joints has recently been demonstrated to be effective and applied to various surgical robots. Although it is a common practice to alternately stack 2N one-degree-of-freedom (1-DOF) units to form a 2-DOF bending joint, it is cumbersome to determine the optimal stacking sequence, and the determined sequence might not satisfy performance requirements. Therefore, in this paper, we propose a new method to construct a 2-DOF discrete bending joint by using 2N + 1 units. The advantages of the proposed method over the previous method of determining the optimal structure by using 2N units are demonstrated quantitatively through kinematic modeling and calculation. As a result, the behavior of the proposed discrete bending joint becomes increasingly similar to that of a continuum joint as the number of units employed in the construction increases. In addition, it is confirmed that the 2N + 1 model can accurately transfer proximal rotation to the distal tip, similarly to a constant velocity joint. It is expected that the proposed simple method for constructing bending joints will be applied to develop various surgical robot structures in the future. © 2019, ICROS, KIEE and Springer. | Suh, Jungwook | Department of Robot and Smart System Engineering, Kyungpook National University (KNU), 80 Daehakro, Bukgu, Daegu, 41566, South Korea | 36606826500 | jwsuh@knu.ac.kr; | International Journal of Control, Automation and Systems | INT J CONTROL AUTOM | 1598-6446 | 2005-4092 | 18 | 1 | SCIE | AUTOMATION & CONTROL SYSTEMS | 2020 | 3.314 | 45.2 | 0.2 | 2025-06-25 | 6 | 2N + 1 unit joints; Continuum joint; discrete bending joint; isotropic bending; laparoscopic instrument; stacking sequence; surgical robot | Degrees of freedom (mechanics); Laparoscopy; Robotic surgery; Robots; Surgery; Complex procedure; Constant velocity joint; Isotropic bending; Laparoscopic instrument; One degree of freedom (1-DOF); Optimal structures; Performance requirements; Stacking sequence; Structural optimization | English | Final | 2020 | 10.1007/s12555-019-0234-y | 바로가기 | 바로가기 | 바로가기 | |||||||
| ○ | ○ | Article | Efficacy of breast MRI for surgical decision in patients with breast cancer: ductal carcinoma in situ versus invasive ductal carcinoma | BackgroundPreoperative breast magnetic resonance imaging (MRI) provides more information than mammography and ultrasonography for determining the surgical plan for patients with breast cancer. This study aimed to determine whether breast MRI is more useful for patients with ductal carcinoma in situ (DCIS) lesions than for those with invasive ductal carcinoma (IDC).MethodsA total of 1113 patients with breast cancer underwent mammography, ultrasonography, and additional breast MRI before surgery. The patients were divided into 2 groups: DCIS (n=199) and IDC (n=914), and their clinicopathological characteristics and oncological outcomes were compared. Breast surgery was classified as follows: conventional breast-conserving surgery (Group 1), partial mastectomy with volume displacement (Group 2), partial mastectomy with volume replacement (Group 3), and total mastectomy with or without reconstruction (Group 4). The initial surgical plan (based on routine mammography and ultrasonography) and final surgical plan (after additional breast MRI) were compared between the 2 groups. The change in surgical plan was defined as group shifting between the initial and final surgical plans.ResultsChanges (both increasing and decreasing) in surgical plans were more common in the DCIS group than in the IDC group (P< 0.001). These changes may be attributed to the increased extent of suspicious lesions on breast MRI, detection of additional daughter nodules, multifocality or multicentricity, and suspicious findings on mammography or ultrasonography but benign findings on breast MRI. Furthermore, the positive margin incidence in frozen biopsy was not different (P=0.138).ConclusionsPreoperative breast MRI may provide more information for determining the surgical plan for patients with DCIS than for those with IDC. | Lee, Jeeyeon; Jung, Jin Hyang; Kim, Wan Wook; Park, Chan Sub; Lee, Ryu Kyung; Kim, Hye Jung; Kim, Won Hwa; Park, Ho Yong | Kyungpook Natl Univ, Sch Med, Dept Surg, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Radiol, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Joint Inst Regenerat Med, Dept Surg, Hoguk Ro 807, Daegu 41404, South Korea | PARK, JUN-YOUNG/P-5981-2015 | 37079213100; 57209310173; 26023273400; 57208483662; 57193539308; 57203506201; 36081886500; 56564377200 | knuh_bts@naver.com; | BMC CANCER | BMC CANCER | 1471-2407 | 20 | 1 | SCIE | ONCOLOGY | 2020 | 4.43 | 45.3 | 0.54 | 2025-06-25 | 7 | 10 | Breast; Ductal carcinoma; Magnetic resonance imaging; Surgical plan | MAGNETIC-RESONANCE; PREOPERATIVE ASSESSMENT; ULTRASOUND; DIAGNOSIS; DCIS; MAMMOGRAPHY; SURGERY; LESIONS; WOMEN | Breast; Ductal carcinoma; Magnetic resonance imaging; Surgical plan | Aged; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Intraductal, Noninfiltrating; Contrast Media; Diagnosis, Differential; Female; Humans; Magnetic Resonance Imaging; Mammography; Margins of Excision; Mastectomy, Segmental; Middle Aged; antineoplastic agent; gadolinium pentetate meglumine; contrast medium; adjuvant radiotherapy; adult; Article; breast biopsy; breast carcinoma; breast reconstruction; breast surgery; cancer adjuvant therapy; cancer hormone therapy; contrast enhancement; controlled study; dynamic contrast-enhanced magnetic resonance imaging; echomammography; human; human tissue; intraductal carcinoma; lymph vessel metastasis; major clinical study; mammography; middle aged; nuclear magnetic resonance imaging; partial mastectomy; preoperative evaluation; simple mastectomy; surgical margin; surgical technique; treatment planning; aged; breast tumor; diagnostic imaging; differential diagnosis; female; intraductal carcinoma; nuclear magnetic resonance imaging; Paget nipple disease; pathology; procedures | English | 2020 | 2020-09-29 | 10.1186/s12885-020-07443-7 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Lifetime survival and medical costs of lung cancer: a semi-parametric estimation from South Korea | BackgroundIt is essential to have information on the disease burden of lung cancer at an individual level throughout the life; however, few such results have been reported. Thus, this study aimed to assess the lifetime disease burden in patients with lung cancer by assessing various factors, such as survival, years of life lost (YLL) and medical expenditure in South Korea based on real-world data and extrapolation.MethodsNewly diagnosed lung cancer patients (n=2919) in 2004-2010 were selected and observed until the end of 2015 using nationwide reimbursement claim database. The patients were categorised into the Surgery group, Chemo and/or Radiotherapy group (CTx/RTx), and Surgery+CTx/RTx according to their treatment modality. Age- and sex-matched control subjects were selected from among general population using the life table. The survival and cost data after diagnosis were analysed by a semi-parametric method, the Kaplan-Meier analysis for the first 100months and rolling extrapolation algorithm for 101-300months. YLL were derived from the difference in survival between patients and controls.ResultsLifetime estimates (standard error) were 4.5 (0.2) years for patients and 14.5 (0.1) years for controls and the derived YLL duration was 10.0 (0.2) years. Lifetime survival years showed the following trend: Surgery (14.2years)>Surgery+CTx/RTx (8.5years)>CTx/RTx group (3.0years), and YLL were increased as lifetime survival years decreased (2.3, 8.7, 12.2years, respectively). The mean lifetime medical cost was estimated at 30,857 USD/patient. Patients in the Surgery group paid higher treatment cost in first year after diagnosis, but the overall mean cost per year was lower at 4359 USD compared with 7075USD of Surgery+CTx/RTx or 7626USD of CTx/RTx group.ConclusionsLung cancer has resulted in about 10years of life lost in overall patients. The losses were associated with treatment modality, and the results indicated that diagnosing lung cancer in patients with low stage disease eligible for surgery is beneficial for reducing disease burden in terms of survival and treatment cost per year throughout the life. | Park, Hae-Young; Hwang, Jinseub; Kim, Do-Hyang; Jeon, Soo Min; Choi, Sun Ha; Kwon, Jin-Won | Kyungpook Natl Univ, Coll Pharm, Daegu 41566, South Korea; Kyungpook Natl Univ, Pharmaceut Sci Res Inst, Daegu 41566, South Korea; Daegu Univ, Div Math & Big Data Sci, Gyongsan 38453, South Korea; Kyungpook Natl Univ, Lung Canc Ctr, Chilgok Hosp, Daegu 41404, South Korea | Kim, Seongjun/HMV-6287-2023; Choi, Sun Ha/HPD-7234-2023 | 57203771734; 57189231296; 57218821860; 57206855645; 57199723585; 16202951700 | jwkwon@knu.ac.kr; | BMC CANCER | BMC CANCER | 1471-2407 | 20 | 1 | SCIE | ONCOLOGY | 2020 | 4.43 | 45.3 | 0.2 | 2025-06-25 | 6 | 6 | Lung cancer; Disease burden; Mortality; Costs; Survival analysis | BURDEN; IMMUNOTHERAPY; DIAGNOSIS; MELANOMA; CARE | Costs; Disease burden; Lung cancer; Mortality; Survival analysis | Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Cost of Illness; Cost-Benefit Analysis; Databases, Factual; Female; Follow-Up Studies; Health Care Costs; Health Expenditures; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Male; Middle Aged; Republic of Korea; Retrospective Studies; Surgical Oncology; Survival Rate; antineoplastic agent; antineoplastic agent; adult; algorithm; Article; cancer chemotherapy; cancer radiotherapy; cancer surgery; cancer survival; controlled study; cost effectiveness analysis; female; follow up; human; lung cancer; major clinical study; male; population research; probability; South Korea; aged; chemoradiotherapy; cost benefit analysis; cost of illness; economics; factual database; health care cost; Kaplan Meier method; lung tumor; middle aged; mortality; retrospective study; surgical oncology; survival rate; very elderly | English | 2020 | 2020-09-03 | 10.1186/s12885-020-07353-8 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Prospective study of oncologic outcomes after laparoscopic modified complete mesocolic excision for non-metastatic right colon cancer (PIONEER study): study protocol of a multicentre single-arm trial | BackgroundThe introduction of complete mesocolic excision (CME) with central vascular ligation (CVL) for right-sided colon cancer has improved the oncologic outcomes. Recently, we have introduced a modified CME (mCME) procedure that keeps the same principles as the originally described CME but with a more tailored approach. Some retrospective studies have reported the favourable oncologic outcomes of laparoscopic mCME for right-sided colon cancer; however, no prospective multicentre study has yet been conducted.MethodsThis study is a multi-institutional, prospective, single-arm study evaluating the oncologic outcomes of laparoscopic mCME for adenocarcinoma arising from the right side of the colon. A total of 250 patients will be recruited from five tertiary referral centres in South Korea. The primary outcome of this study is 3-year disease-free survival. Secondary outcome measures include 3-year overall survival, incidence of surgical complications, completeness of mCME, and distribution of metastatic lymph nodes. The quality of laparoscopic mCME will be assessed on the basis of photographs of the surgical specimen and the operation field after the completion of lymph node dissection.DiscussionThis is a prospective multicentre study to evaluate the oncologic outcomes of laparoscopic mCME for right-sided colon cancer. To the best of our knowledge, this will be the first study to prospectively and objectively assess the quality of laparoscopic mCME. The results will provide more evidence about oncologic outcomes with respect to the quality of laparoscopic mCME in right-sided colon cancer.Trial registrationClinicalTrials.gov ID: NCT03992599 (June 20, 2019). The posted information will be updated as needed to reflect protocol amendments and study progress. | Yang, Seung Yoon; Kim, Min Jung; Kye, Bong-Hyeon; Han, Yoon Dae; Cho, Min Soo; Jeong, Seung-Yong; Cho, Hyeon-Min; Kim, Hyunki; Kang, Gyeong Hoon; Song, Seung Ho; Park, Jun Seok; Kim, Ji-Seon; Park, Soo Yeun; Kim, Jin; Min, Byung Soh | Yonsei Univ, Severance Hosp, Dept Surg, Coll Med, 50 Yonsei Ro, Seoul 120752, South Korea; Seoul Natl Univ, Dept Surg, Coll Med, Seoul, South Korea; Catholic Univ Korea, Dept Surg, Sch Med, Seoul, South Korea; Yonsei Univ, Dept Pathol, Coll Med, Seoul, South Korea; Seoul Natl Univ, Dept Pathol, Coll Med, Seoul, South Korea; Kyungpook Natl Univ, Sch Med, Dept Surg, Daegu, South Korea; Korea Univ, Dept Surg, Coll Med, 73 Goryeodae Ro, Seoul, South Korea | Kim, Hee/F-4594-2014; Kim, You Sun/B-2881-2015; Jeong, Seung-Yong/J-5643-2012; Cho, Kwang/J-5661-2012; Kang, Gyeong Hoon/F-1051-2010; Han, Yoondae/W-1325-2019; Park, Junsu/IQU-2241-2023 | 57193152513; 56984393300; 36022461900; 56877960900; 37664649800; 7402425099; 31168246400; 55767130300; 57049735100; 57221771693; 35226761100; 57221538018; 40561578300; 55720304300; 35269560900 | psy.flower@hanmail.net;mrgs@korea.ac.kr;bsmin@yuhs.ac;psy-flower@hanmail.net; | BMC CANCER | BMC CANCER | 1471-2407 | 20 | 1 | SCIE | ONCOLOGY | 2020 | 4.43 | 45.3 | 0.27 | 2025-06-25 | 6 | 6 | Modified complete mesocolic excision; Laparoscopic surgery; Right-sided colon cancer; Oncologic outcomes | CENTRAL VASCULAR LIGATION; SURGERY; SURVIVAL; ASSOCIATION; DISSECTION; RESECTION; QUALITY | Laparoscopic surgery; Modified complete mesocolic excision; Oncologic outcomes; Right-sided colon cancer | Adenocarcinoma; Adult; Aged; Aged, 80 and over; Clinical Trials as Topic; Colectomy; Colonic Neoplasms; Follow-Up Studies; Humans; Laparoscopy; Lymph Node Excision; Mesocolon; Middle Aged; Multicenter Studies as Topic; Prognosis; Prospective Studies; Republic of Korea; Research Design; Survival Rate; Young Adult; adult; Article; ascending colon; cancer localization; cancer patient; cancer surgery; cancer survival; cancer tissue; clinical outcome; clinical trial; clinical trial protocol; colon adenocarcinoma; disease free survival; female; human; human tissue; incidence; laparoscopic surgery; lymph node dissection; lymph node metastasis; major clinical study; male; mesocolon; multicenter study; oncological parameters; overall survival; photography; postoperative complication; prospective study; quality control; South Korea; tertiary care center; adenocarcinoma; aged; clinical trial (topic); colon resection; colon tumor; follow up; laparoscopy; mesocolon; methodology; middle aged; mortality; multicenter study (topic); pathology; prognosis; survival rate; very elderly; young adult | English | 2020 | 2020-07-14 | 10.1186/s12885-020-07151-2 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Utility of ¹⁸F-FDG PET/CT for predicting pathologic complete response in hormone receptor-positive, HER2-negative breast cancer patients receiving neoadjuvant chemotherapy | BackgroundPathologic complete response (pCR) after neoadjuvant chemotherapy (NAC) is a predictor of improved outcomes in breast cancer. In patients with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2) -negative breast cancer, the response to NAC is variable and mostly limited. This study was an investigation of the predictive relevance of parameters of F-18-FDG PET/CT for the pCR to NAC in patients with HR-positive, HER2-negative breast cancer. Methods: AH total of 109 consecutive HR-positive and HER2-negative breast cancer patients who were treated with NAC were enrolled in this prospective cohort study. The relationships between pretreatment F-18-FDG PET/CT and clinical outcomes including pathologic response to NAC were evaluated. Results: All patients finished their planned NAC cycles and eight patients (7.3%) achieved pCR. In the receiver operating characteristic (ROC) curve analysis, pSUVmax exhibited high sensitivity and specificity for predicting pCR. Furthermore, multivariate logistic regression analysis revealed pSUVmax as a predictive factor for pCR (hazard ratio=17.452; 95% CI=1.847-164.892; p=0.013).ConclusionThe results of this study suggest that F-18-FDG PET/CT pSUVmax is a predictive factor for pCR of HR-positive, HER2-negative breast cancer to NAC. | Lee, In Hee; Lee, Soo Jung; Lee, Jeeyeon; Jung, Jin Hyang; Park, Ho Yong; Jeong, Shin Young; Lee, Sang-woo; Chae, Yee Soo | Catholic Univ Daegu, Sch Med, Dept Oncol Hematol, Daegu, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Chilgok Hosp, Dept Oncol Hematol, Daegu, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Chilgok Hosp, Dept Breast & Thyroid Surg, Daegu, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Chilgok Hosp, Dept Nucl Med, Daegu, South Korea | PARK, JUN-YOUNG/P-5981-2015 | 56390538200; 57203597252; 37079213100; 57209310173; 56564377200; 36164032500; 57196249819; 57190793908 | yschae@knu.ac.kr; | BMC CANCER | BMC CANCER | 1471-2407 | 20 | 1 | SCIE | ONCOLOGY | 2020 | 4.43 | 45.3 | 0.61 | 2025-06-25 | 13 | 14 | Breast cancer; Neoadjuvant chemotherapy; Pathologic complete response; SUVmax | INTERNATIONAL EXPERT CONSENSUS; SURGICAL ADJUVANT BREAST; PREOPERATIVE CHEMOTHERAPY; SYSTEMIC THERAPY; PROGNOSIS; HIGHLIGHTS; METABOLISM; ESTROGEN; SUBTYPES; TUMOR | Breast cancer; Neoadjuvant chemotherapy; Pathologic complete response; SUVmax | Adenocarcinoma, Mucinous; Adult; Aged; Biomarkers, Tumor; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Female; Fluorodeoxyglucose F18; Follow-Up Studies; Humans; Middle Aged; Neoadjuvant Therapy; Positron Emission Tomography Computed Tomography; Prognosis; Radiopharmaceuticals; Receptor, ErbB-2; Receptors, Estrogen; Receptors, Progesterone; Survival Rate; anthracycline; cyclophosphamide; docetaxel; fluorodeoxyglucose f 18; epidermal growth factor receptor 2; ERBB2 protein, human; estrogen receptor; progesterone receptor; radiopharmaceutical agent; tumor marker; adult; aged; Article; cohort analysis; female; hazard ratio; histology; human; human epidermal growth factor receptor 2 negative breast cancer; human tissue; immunohistochemistry; major clinical study; mastectomy; multiple cycle treatment; multivariate logistic regression analysis; neoadjuvant chemotherapy; outcome assessment; partial mastectomy; positron emission tomography-computed tomography; prospective study; receiver operating characteristic; sensitivity and specificity; survival analysis; treatment response; breast tumor; colloid carcinoma; diagnostic imaging; follow up; lobular carcinoma; metabolism; middle aged; neoadjuvant therapy; Paget nipple disease; pathology; positron emission tomography-computed tomography; procedures; prognosis; survival rate | English | 2020 | 2020-11-16 | 10.1186/s12885-020-07505-w | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Clinical features and treatment outcomes of limited-stage mantle cell lymphoma: Consortium for Improving Survival of Lymphoma report | Limited-stage (Ann Arbor stage I or II) mantle cell lymphoma (MCL) is an extremely rare disease. Thus, there is little data on the clinical features and treatment outcomes of patients with early-stageMCL. We examined consecutive stage I or II MCL 41 cases diagnosed between 2000 and 2016 in 16 institutions of the Consortium for Improving Survival of Lymphoma group. All cases were pathologically confirmed and systemic evaluation was performed for staging. The clinical features were reviewed, and the treatment outcomes were analyzed. The median age of patients was 66 years (range 19-85 years); there were more men (n = 31, 75.6%) than women. Most patients (n = 28, 68.3%) had stage 2 disease, and 29 (70.7%) were symptomatic. The elevation of lactate dehydrogenase (n = 2, 4.9%) was not common; thus, 39 patients (95.1%) had a low-risk score (0 or 1) for the International Prognostic Index, and 28 (68.3%) had a low-risk score (1-3) for the MCL International Prognostic Index. Most patients (n = 37, 90.1%) received chemotherapy as the first therapeutic strategy, while some received radiotherapy (n = 2), surgical resection (n = 1), or no treatment (n = 1). Of the patients who received chemotherapy, 23 (56.9%) received a rituximab-containing regimen, and R-CHOP (n = 17) and R-bendamustine (n = 5) were commonly used. The best response was noted in 97.4% (n = 38) of patients, including 32 who showed a complete response (78%). With a median follow-up duration of 40.6 months, the 42 months relapse-free survival was 59.1%, and the 5-year overall survival rate was 80.4%. Limited-state MCL showed indolent clinical and low-risk prognostic features. Chemotherapy could be effective for controlling localized MCL lesions, with high complete response rates. | Jo, Jae-Cheol; Kim, Seok Jin; Lee, Ho Sup; Eom, Hyeon-Seok; Lee, Soon Il; Park, Yong; Lee, Jeong-Ok; Lee, Yoojin; Yhim, Ho-Young; Yang, Deok-Hwan; Byun, Ja Min; Kang, Hye Jin; Kim, Hyo Jung; Shin, Ho-Jin; Yoo, Kwai Han; Suh, Cheolwon | Univ Ulsan, Ulsan Univ Hosp, Coll Med, Dept Hematol & Oncol, Ulsan, South Korea; Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Med,Div Hematol Oncol, Seoul, South Korea; Kosin Univ, Coll Med, Dept Internal Med, Busan, South Korea; Natl Canc Ctr Korea, Dept Internal Med, Goyang, South Korea; Dankook Univ, Coll Med, Dept Internal Med, Yongin, South Korea; Korea Univ, Coll Med, Dept Internal Med, Seoul, South Korea; Seoul Natl Univ, Bundang Hosp, Dept Internal Med, Div Hematol Oncol, Seoul, South Korea; Kyungpook Natl Univ Hosp, Dept Internal Med, Daegu, South Korea; Chonbuk Natl Univ Hosp, Dept Internal Med, Div Hematol & Oncol, Jeonju, South Korea; Chonnam Natl Univ Hwasun Hosp, Dept Hematol Oncol, Jeonnam, Hwasun County, South Korea; Seoul Natl Univ, Boramae Hosp, Dept Internal Med, Seoul, South Korea; Korea Canc Ctr Hosp, Korea Inst Radiol & Med Sci, Dept Internal Med, Div Hematol & Oncol, Seoul, South Korea; Hallym Univ, Sacred Heart Hosp, Hallym Med Ctr, Dept Internal Med, Anyang, South Korea; Pusan Natl Univ Hosp, Dept Internal Med, Busan, South Korea; Gachon Univ, Gil Hosp, Dept Internal Med, Seongnam, South Korea; Univ Ulsan, Coll Med, Asan Med Ctr, Dept Oncol, 88 Olymp Ro 43 Gil, Seoul 138736, South Korea | Lee, Jong-Seok/J-5603-2012; Kim, Hyo/AAQ-3152-2020; Lee, In/J-9324-2013; Liu, Jingwei/AAZ-9739-2021; Yhim, Ho-Young/J-1531-2012; Kang, Hye Jin/HKV-9155-2023; Jo, Jae-Cheol/CAE-9453-2022; Lee, Yoojin/AAB-9799-2022; Byun, Ja/AAI-2125-2020; KIM, JIN/I-6927-2019 | 35818309200; 36521373300; 57218103550; 35268272400; 55716345500; 7405373234; 40361307900; 57188669696; 35785270600; 8701758000; 57191727590; 23497013500; 7410139194; 16239868400; 56396023400; 7102970953 | csuh@amc.seoul.kr; | ANNALS OF HEMATOLOGY | ANN HEMATOL | 0939-5555 | 1432-0584 | 99 | 2 | SCIE | HEMATOLOGY | 2020 | 3.673 | 45.4 | 0.22 | 2025-06-25 | 7 | 5 | Limited stage; Mantle cell lymphoma; Prognosis | IMMUNOCHEMOTHERAPY; INDEX; MCL | Limited stage; Mantle cell lymphoma; Prognosis | Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Cyclophosphamide; Disease-Free Survival; Doxorubicin; Female; Follow-Up Studies; Humans; Lymphoma, Mantle-Cell; Male; Middle Aged; Neoplasm Staging; Prednisone; Radiotherapy; Retrospective Studies; Risk Factors; Rituximab; Survival Rate; Time Factors; Vincristine; bendamustine; carboplatin; cyclophosphamide; cytarabine; dexamethasone; doxorubicin; etoposide; ibrutinib; ifosfamide; lactate dehydrogenase; prednisolone; prednisone; rituximab; vincristine; antineoplastic agent; bendamustine; cyclophosphamide; doxorubicin; prednisone; R-CHOP protocol; rituximab; vincristine; adult; age; aged; allogeneic stem cell transplantation; Article; autologous stem cell transplantation; cancer chemotherapy; cancer diagnosis; cancer localization; cancer prognosis; cancer radiotherapy; cancer recurrence; cancer risk; cancer staging; cancer surgery; cancer survival; clinical evaluation; clinical feature; cohort analysis; distant metastasis; drug efficacy; female; follow up; human; International Prognostic Index; lactate dehydrogenase blood level; major clinical study; male; mantle cell lymphoma; Mantle Cell Lymphoma International Prognostic Index; molecular pathology; outcome assessment; overall survival; priority journal; recurrence free survival; retrospective study; risk assessment; salvage therapy; survival analysis; survival rate; survival time; treatment outcome; treatment response; cancer staging; clinical trial; disease free survival; mantle cell lymphoma; middle aged; mortality; multicenter study; pathology; radiotherapy; risk factor; time factor; very elderly | English | 2020 | 2020-02 | 10.1007/s00277-019-03803-x | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Correction | Clinical outcomes in patients with diffuse large B cell lymphoma with a partial response to first-line R-CHOP chemotherapy: prognostic value of secondary International Prognostic Index scores and Deauville scores (vol 78, pg 238, 2019) | Lee, Hyewon; Kim, Yu Ri; Kim, Soo-Jeong; Park, Yong; Eom, Hyeon-Seok; Oh, Sung Yong; Kim, Hyo Jung; Kang, Hye Jin; Lee, Won-Sik; Moon, Joon Ho; Won, Young-Woong; Kim, Tae-Sung; Kim, Jin Seok | Natl Canc Ctr, Ctr Hematol Malignancy, Goyang, South Korea; Yonsei Univ, Gangnam Severance Hosp, Dept Internal Med, Coll Med, Seoul, South Korea; Yonsei Univ, Severance Hosp, Dept Internal Med, Div Hematol,Coll Med, 50-1 Yonsei Ro, Seoul 03722, South Korea; Korea Univ, Coll Med, Dept Internal Med, Div Hematol Oncol, Seoul, South Korea; Dong A Univ, Dept Internal Med, Coll Med, Busan, South Korea; Hallym Univ, Sacred Heart Hosp, Div Hematol Oncol, Dept Internal Med,Coll Med, Anyang, South Korea; Korea Inst Radiol & Med Sci, Div Hematol Oncol, Dept Internal Med, Korea Canc Ctr Hosp, Seoul, South Korea; Inje Univ, Busan Paik Hosp, Div Hematol Oncol, Dept Internal Med,Coll Med, Busan, South Korea; Kyungpook Natl Univ Hosp, Dept Hematol & Med Oncol, Daegu, South Korea; Hanyang Univ, Dept Internal Med, Coll Med, Seoul, South Korea; Natl Canc Ctr, Dept Nucl Med, Goyang, South Korea; Yonsei Univ, Dept Internal Med, Coll Med, Seoul, South Korea | Gim, Yuri/JNZ-3445-2023; Kang, Hye Jin/HKV-9155-2023; Kim, Hyo/AAQ-3152-2020 | 57221571257; 56215488700; 56596895200; 7405373234; 35268272400; 56601510200; 7410139194; 23497013500; 55556573100; 56568642700; 8982855700; 59604850800; 55032033600 | hemakim@yuhs.ac; | ANNALS OF HEMATOLOGY | ANN HEMATOL | 0939-5555 | 1432-0584 | 99 | 1 | SCIE | HEMATOLOGY | 2020 | 3.673 | 45.4 | 0 | 2025-06-25 | 0 | 0 | erratum | English | 2020 | 2020-01 | 10.1007/s00277-019-03868-8 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||||
| ○ | ○ | Article | Enhancing electrochemical degradation of phenol at optimum pH condition with a Pt/Ti anode electrode | Electrochemical phenol degradation using a platinum-coated Ti electrode was comparatively investigated at different pH levels, which were maintained over the entire operation period. Various analyses such as phenol concentration, TOC, COD, cyclic voltammetry, and total current efficiency were conducted to determine the performance of phenol degradation in the presence of Na2SO4 as the electrolyte. The phenol and COD removal rate were relatively higher at lower pH conditions (pH 3 and 5) due to high oxidant generation of OH radical and H2O2. At pH 5 condition, phenol (90 mg L-1) was completely removed after a 24-h operation. However, complete COD removal was obtained after about 250-h operation, due to byproduct formations (hydroquinone and polymers) during the phenol degradation. Cyclic voltammetry analysis indicated that acidic conditions could inhibit the oxygen-evolution reaction, causing an increase in current efficiency and a decrease in energy consumption. This study suggests that phenol-contaminated wastewater can be efficiently treated by an electrochemical process using a Pt/Ti electrode with continuously controlled lower pH conditions.Phenol oxidation by electrochemical treatment system at different pH conditions Electrochemical reactor (inside) R: reference electrode, A: Pt/Ti anode, C: Ti cathode, G: pipe to the gas bag, S: sample holder, M: magnetic stirrer | Zambrano, Johanna; Park, Hyunwoong; Min, Booki | Kyung Hee Univ, Dept Environm Sci & Engn, Namyangju Si 446701, Gyeonggi Do, South Korea; Kyungpook Natl Univ, Sch Energy Engn, Daegu, South Korea | Park, Hyunwoong/A-1247-2012; Zambrano, Johanna/X-5567-2019 | 57208719118; 7601565583; 35240874800 | bkmin@khu.ac.kr; | ENVIRONMENTAL TECHNOLOGY | ENVIRON TECHNOL | 0959-3330 | 1479-487X | 41 | 24 | SCIE | ENVIRONMENTAL SCIENCES | 2020 | 3.247 | 45.4 | 0.97 | 2025-06-25 | 24 | 26 | Electrochemical oxidation; phenol; Pt; Ti electrode; pH condition; OH radical | REMOVING PETROLEUM-HYDROCARBONS; WASTE-WATER; OXIDATION PROCESSES; DYE; PLATINUM; FENTON; TECHNOLOGY; POLLUTANTS; ABATEMENT; ACID | Electrochemical oxidation; OH radical; pH condition; phenol; Pt/Ti electrode | Electrodes; Hydrogen Peroxide; Hydrogen-Ion Concentration; Oxidation-Reduction; Phenol; Phenols; Titanium; Water Pollutants, Chemical; Anodes; Biodegradation; Chemical oxygen demand; Chemicals removal (water treatment); Cyclic voltammetry; Electrochemical oxidation; Electrolytes; Energy efficiency; Energy utilization; Free radicals; Oxygen evolution reaction; pH; Phenols; Platinum compounds; Sodium sulfate; Titanium compounds; Wastewater treatment; hydroquinone; phenol; platinum; polymer; sodium sulfate; titanium; hydrogen peroxide; phenol derivative; titanium; Contaminated wastewater; Electrochemical degradation; Electrochemical process; Electrochemical reactor; Electrochemical treatments; OH radical; pH condition; Phenol concentration; chemical oxygen demand; degradation; electrochemistry; electrode; oxygen; pH; phenol; platinum; pollutant removal; titanium; chemical oxygen demand; comparative study; cyclic voltammetry; degradation kinetics; energy consumption; waste component removal; waste water; water contamination; electrode; oxidation reduction reaction; pH; water pollutant; Electrochemical electrodes | English | 2020 | 2020-10-27 | 10.1080/09593330.2019.1649468 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Gender differences in clinical outcomes of acute myocardial infarction undergoing percutaneous coronary intervention: insights from the KAMIR-NIH Registry | Background There are numerous but conflicting data regarding gender differences in outcomes following percutaneous coronary intervention (PCI). Furthermore, gender differences in clinical outcomes with acute myocardial infarction (AMI) following PCI in Asian population remain uncertain because of the under-representation of Asian in previous trials. Methods A total of 13,104 AMI patients from Korea Acute Myocardial Infarction Registry-National Institute of Health (KAMIR-NIH) between November 2011 and December 2015 were classified into male (n = 8021, 75.9%) and female (n = 2547, 24.1%). We compared the demographic, clinical and angiographic characteristics, 30-days and 1-year major adverse cardiac and cerebrovascular events (MACCE) in women with those in men after AMI by using propensity score (PS) matching. Results Compared with men, women were older, had more comorbidities and more often presented with non-ST segment elevation myocardial infarction (NSTEMI) and reduced left ventricular systolic function. Over the median follow-up of 363 days, gender differences in both 30-days and 1-year MACCE as well as thrombolysis in myocardial infarction minor bleeding risk were not observed in the PS matched population (30-days MACCE: 5.3% vs. 4.7%, log-rank P = 0.494, HR = 1.126, 95% CI: 0.800-1.585; 1-year MACCE: 9.3% vs. 9.0%, log-rank P = 0.803, HR = 1.032, 95% CI: 0.802-1.328; TIMI minor bleeding: 4.9% vs. 3.9%, log-rank P = 0.215, HR = 1.255, 95% CI: 0.869-1.814). Conclusions Among Korean AMI population undergoing contemporary PCI, women, as compared with men, had different clinical and angiographic characteristics but showed similar 30-days and 1-year clinical outcomes. The risk of bleeding after PCI was comparable between men and women during one-year follow up. | Lee, Myunhee; Kim, Dae-Won; Park, Mahn-Won; Lee, Kyusup; Chang, Kiyuk; Chung, Wook Sung; Ahn, Tae Hoon; Jeong, Myung Ho; Rha, Seung-Woon; Kim, Hyo-Soo; Gwon, Hyeon Cheol; Seong, In Whan; Hwang, Kyung Kuk; Chae, Shung Chull; Kim, Kwon-Bae; Kim, Young Jo; Cha, Kwang Soo; Oh, Seok Kyu; Chae, Jei Keon; Jung, Ji-Hoon | Catholic Univ Korea, Coll Med, Div Cardiol, Daejeon St Marys Hosp, Seoul, South Korea; Catholic Univ Korea, Coll Med, Div Cardiol, Seoul St Marys Hosp, Seoul, South Korea; Gachon Univ, Gil Med Ctr, Incheon, South Korea; Korea Univ, Chonnam Natl Univ Hosp, Gwangju, South Korea; Korea Univ, Guro Hosp, Seoul, South Korea; Seoul Natl Univ Hosp, Seoul, South Korea; Sungkyunkwan Univ, Samsung Med Ctr, Seoul, South Korea; Chungnam Natl Univ Hosp, Daejeon, South Korea; Chungbuk Natl Univ Hosp, Cheongju, South Korea; Kyungpook Natl Univ Hosp, Daegu, South Korea; Keimyung Univ, Dongsan Med Ctr, Daegu, South Korea; Yeungnam Univ Hosp, Daegu, South Korea; Pusan Natl Univ Hosp, Busan, South Korea; Wonkwang Univ Hosp, Iksan, South Korea; Chonbuk Natl Univ Hosp, Jeonju, South Korea; Inst Toxicol, Daejeon, South Korea | ; 안, 태훈/GON-9067-2022; Park, M.J./Y-5611-2019; Kim, Hyo/J-2753-2012; Lee, Myunhee/KBC-5100-2024; Rha, Seung-Woon/AGE-5810-2022 | 57223112782; 57199419487; 57751047500; 57204923370; 25521288100; 7401983318; 57222278496; 56485157500; 8569030400; 33567809200; 6603262426; 57209742532; 7402426370; 7101962036; 8319343800; 8356521500; 7102837700; 59588435100; 26029709000; 57204175011 | mirinesilver@catholic.ac.kr; | JOURNAL OF GERIATRIC CARDIOLOGY | J GERIATR CARDIOL | 1671-5411 | 17 | 11 | SCIE | CARDIAC & CARDIOVASCULAR SYSTEMS;GERIATRICS & GERONTOLOGY | 2020 | 3.327 | 45.4 | 0.33 | 2025-06-25 | 9 | 6 | Acute myocardial infarction; Asian population; Gender difference; Percutaneous coronary intervention | IN-HOSPITAL MORTALITY; DRUG-ELUTING STENTS; SEX-DIFFERENCES; AMERICAN-COLLEGE; NATIONAL-HEART; ARTERY-DISEASE; WOMEN; ANGIOPLASTY; MEN; MANAGEMENT | Acute myocardial infarction; Asian population; Gender difference; Percutaneous coronary intervention | acetylsalicylic acid; beta adrenergic receptor blocking agent; brain natriuretic peptide; C reactive protein; clopidogrel; fibrinogen receptor antagonist; prasugrel; ticagrelor; acute heart infarction; adult; aged; Article; bleeding; cardiovascular mortality; cause of death; cerebrovascular accident; clinical outcome; cohort analysis; comorbidity; female; follow up; heart death; heart failure; human; left anterior descending coronary artery; left ventricular systolic dysfunction; loading drug dose; major adverse cardiac event; major clinical study; male; middle aged; morbidity; multicenter study; non ST segment elevation myocardial infarction; observational study; percutaneous coronary intervention; propensity score; prospective study; register; sex difference; ST segment elevation myocardial infarction; stent thrombosis; target vessel revascularization | English | 2020 | 2020 | 10.11909/j.issn.1671-5411.2020.11.006 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Role of various factors affecting the photochemical treatment of N-nitrosamines related to CO2 capture | Post-combustion CO2 capture using amine solvents is the most feasible method of reducing anthropogenic CO2 emissions, which are the largest contributor to global warming. The formation of carcinogenic N-nitrosamines (i.e. by-products) can hinder the industrial application of this technology. In this study, the effects of direct UV photolysis (N-nitrosamine concentration and amines) and advanced oxidation processes (UV/H2O2 and UV/O-3) on the three specific N-nitrosamines that are commonplace in amine-based CO2 capture (i.e. N-nitrosodiethylamine (NDEA), N-nitrosodiethanolamine (NDELA), and N-nitrosomorpholine (NMOR)) were examined. A significant decrease in the photodegradation rate constants was observed for NDEA (1.02 x 10(0) to 2.94 x 10(-1) min(-1)), NDELA (1.52 x 10(0) to 3.32 x 10(-1) min(-1)), and NMOR (1.93 x 10(0) to 2.20 x 10(-1) min(-1)) as their concentrations increased within 1-50 mg/L. This is the first report of a significant increase in the degradation rate constants of N-nitrosamine with an increase in amine concentrations (i.e. monoethanolamine, diethanolamine, and morpholine) within 10-200 mM. The photodegradation rate constants increased as the molar ratio of H2O2 to N-nitrosamine increased to 20, but then decreased at molar ratios beyond this. O-3 had a negligible effect on the photodegradation of N-nitrosamines. | Aqeel, Afzal; Lim, Ho-Jin | Kyungpook Natl Univ, Dept Environm Engn, Daegu 41566, South Korea | Afzal, Aqeel/JKL-1217-2023 | 57195247194; 56883100200 | hjlim@knu.ac.kr; | ENVIRONMENTAL TECHNOLOGY | ENVIRON TECHNOL | 0959-3330 | 1479-487X | 41 | 11 | SCIE | ENVIRONMENTAL SCIENCES | 2020 | 3.247 | 45.4 | 0.23 | 2025-06-25 | 2 | 5 | N-nitrosamine; photodegradation; hydrogen peroxide; ozone; CO2 capture | CARBON-DIOXIDE CAPTURE; NITRAMINE FORMATION; DEGRADATION; NITROSODIMETHYLAMINE; AMINES; WATER; MONOETHANOLAMINE; DECOMPOSITION; OXIDATION; PHOTODEGRADATION | CO<sub>2</sub> capture; hydrogen peroxide; N-nitrosamine; ozone; photodegradation | Amines; Carbon Dioxide; Ethanolamine; Hydrogen Peroxide; Nitrosamines; Carbon dioxide; Degradation; Ethanolamines; Global warming; Molar ratio; Nitrosamines; Photolysis; bis(2 hydroxyethyl)nitrosamine; carbon dioxide; diethanolamine; diethylnitrosamine; ethanolamine; hydrogen peroxide; morpholine; nitrosamine; nitrosomorpholine; amine; carbon dioxide; Advanced Oxidation Processes; Amine solvents; Degradation rate constants; Monoethanolamine; N-nitrosodiethanolamine; N-nitrosodiethylamine; Photodegradation rate; Post-combustion; carbon dioxide; carbon emission; chemical compound; concentration (composition); detection method; oxidation; photochemistry; photodegradation; photolysis; solvent; carbon dioxide capture; carbon footprint; oxidation; photochemistry; photodegradation; photolysis; ultraviolet radiation; waste management; Rate constants | English | 2020 | 2020-05-11 | 10.1080/09593330.2018.1536172 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
페이지 이동: