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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Article | Tick Populations and Molecular Analysis of Anaplasma Species in Ticks from the Republic of Korea | The present study was performed to survey the dominant tick populations and molecularly determine the pathogenic agents of anaplasmosis in ticks from Gyeongsang, Republic of Korea. A total of 3825 questing ticks were collected by the flagging method from 12 sites near animal farms in Gyeongsang from March to October 2021. A molecular genomic study was performed with ticks stored in 70% ethanol to detect Anaplasma genes by the previously described method. The monthly incidence of ticks varied by developmental stages, i.e., nymphs, adults, and larvae, and each of their populations peaked in May, March, and October, respectively. The predominant tick species were Haemaphysalis longicornis, Haemaphysalis sp., Haemaphysalis flava, Ixodes nipponensis, and Amblyomma testudinarium in order. To determine the Anaplasma infection rate, collected ticks were pooled into 395 groups. The minimum infection rate (MIR) of Anaplasma was 0.7% (27 pools). That of A. phagocytophilum was highest (23 pools, MIR 0.6%), followed by A. phagocytophilum-like Anaplasma spp. clade B (2 pools, MIR 0.1%), A. bovis (1 pool, MIR 0.1%), and A. capra (1 pool, MIR 0.1%), respectively. In this study, five species of ticks, including unidentified Haemaphysalis species, were collected in 12 survey sites in Gyeongsang, but their prevalence was somewhat different according to the tick species and survey sites. Further, the incidence rate (6.8%) of 4 Anaplasma spp. was not as high in tick pools. However, the results of this study may offer a basis for future epidemiological research and risk assessment of tick-borne diseases. | Seo, Min-Goo; Lee, Haeseung; Alkathiri, Badriah; Ahn, KyuSung; Lee, Seung-Hun; Shin, SungShik; Bae, Seulgi; Kim, Kyoo-Tae; Jang, Min; Lee, Sang-Kwon; Cho, Yun Sang; Eo, Kyung-Yeon; Kwon, Oh-Deog; Kwak, Dongmi | Kyungpook Natl Univ, Coll Vet Med, Daegu 41566, South Korea; Anim & Plant Quarantine Agcy, Gimcheon 39660, South Korea; Chungbuk Natl Univ, Coll Vet Med, Cheongju 28644, South Korea; Chonnam Natl Univ, Coll Vet Med, Dept Parasitol, Gwangju 61186, South Korea; Semyung Univ, Coll Healthcare & Biotechnol, Dept Anim Hlth & Welf, Jecheon 27136, South Korea | ; Seo, Min-Goo/NQF-4335-2025; Cho, Yun Sang/ACA-6165-2022 | 53982155300; 57202497862; 57190979864; 36004623300; 57203394416; 7403646673; 55418865900; 56680415000; 55341507600; 56494541400; 16066666200; 26631541100; 7402195886; 7007148758 | dmkwak@knu.ac.kr; | MICROORGANISMS | MICROORGANISMS | 2076-2607 | 11 | 4 | SCIE | MICROBIOLOGY | 2023 | 4.1 | 30.1 | 1.18 | 2025-06-25 | 6 | 7 | Anaplasma phagocytophilum; Anaplasma phagocytophilum-like Anaplasma spp; Anaplasma bovis; Anaplasma capra; questing tick | EHRLICHIA-EQUI; PHAGOCYTOPHILUM; CATTLE; RICKETTSIALES; INFECTION; DISEASES; HUMANS; HORSES; SPP. | Anaplasma bovis; Anaplasma capra; Anaplasma phagocytophilum; Anaplasma phagocytophilum-like Anaplasmaspp; questing tick | English | 2023 | 2023-04 | 10.3390/microorganisms11040820 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | What Is the Linear Accuracy of Regional Voxel-Based Registration for Landmarks? | Purpose: While regional voxel-based registration (R-VBR) has been shown to have excellent reproducibility and angular accuracy, there are limited data on the linear accuracy of R-VBR for common orthognathic surgery landmarks, or on whether angular accuracy correlates with linear accuracy. The purpose of this study was to estimate the linear accuracy of R-VBR for several skeletal landmarks commonly used in orthognathic surgical planning, and to measure the correlation between angular and linear discrepancies. Materials and Methods: This is a retrospective cross-sectional study of consecutive patients treated at a single center with nonsegmental LeFort I and bilateral sagittal split osteotomy surgery from January 2019 to November 2020. Cone beam computed tomography at the preoperative (T0) and immediate postoperative (T1) stages were analyzed to measure the postoperative positional changes of 11 orthognathic land-marks in 4 regions of interest (ROI) using R-VBR performed twice by two examiners. Pairwise correlation analysis and canonical correlation analysis were performed for the angular discrepancies (primary predictor variable) and the linear discrepancies (primary outcome variable) to measure the correlation between the two. Results: In cone beam computed tomography analysis of 28 eligible subjects (16 males, 12 females; mean age 18.9 years, range 15 to 25), the mean absolute (MA) angular discrepancies ranged from 0.15 degrees to 0.55 degrees, while the corresponding MA linear discrepancies ranged from 0.05 to 0.41 mm. There was a strong correlation between angular and linear discrepancies that was statistically significant (P = .001 to .04, Spearman's rank correlation coefficient 0.38 to 0.87). Conclusions: For nonsegmental LeFort I osteotomies and bilateral sagittal split osteotomy, R-VBR has excellent linear accuracy within a single voxel size (0.3 mm) for commonly used orthognathic landmarks in the maxillary and distal mandibular ROI. The MA linear discrepancy for the proximal mandibular segment ROI was greater than a single voxel size, with a maximum of 0.41 mm. (c) 2023 American Association of Oral and Maxillofacial Surgeons | Han, Michael D.; Kwon, Tae-Geon; Miloro, Michael; Chakrabarty, Sayan | Univ Illinois, Dept Oral & Maxillofacial Surg, Chicago, IL USA; Kyungpook Natl Univ, Dept Oral & Maxillofacial Surg, Daegu, South Korea; Univ Illinois, Dept Stat, Stat Consultant, Champaign, IL USA; Univ Illinois, Oral & Maxillofacial Surg, 801 S Paulina St,Room 110, Chicago, IL 60612 USA | Chakrabarty, Sayan/LWZ-8030-2024 | 57195322718; 35205433300; 7004249840; 57219692587 | hanmd@uic.edu; | JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY | J ORAL MAXIL SURG | 0278-2391 | 1531-5053 | 81 | 5 | SCIE | DENTISTRY, ORAL SURGERY & MEDICINE | 2023 | 2.3 | 30.1 | 1.01 | 2025-06-25 | 2 | 3 | ORTHOGNATHIC SURGERY; RELIABILITY | Adolescent; Adult; Cone-Beam Computed Tomography; Cross-Sectional Studies; Female; Humans; Imaging, Three-Dimensional; Male; Orthognathic Surgery; Orthognathic Surgical Procedures; Reproducibility of Results; Retrospective Studies; Young Adult; adult; article; bilateral sagittal split osteotomy; clinical article; cone beam computed tomography; controlled study; correlation analysis; correlation coefficient; cross-sectional study; female; human; male; mandible; maxilla; orthognathic surgery; osteotomy; outcome assessment; outcome variable; predictor variable; retrospective study; young adult; adolescent; procedures; reproducibility; three-dimensional imaging | English | 2023 | 2023-05 | 10.1016/j.joms.2023.01.015 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Correlation of paleoearthquake records at multiple sites along the southern Yangsan Fault, Korea: Insights into rupture scenarios of intraplate strike-slip earthquakes | The construction of spatiotemporal models of earthquake occurrence for intraplate areas is challenging due to the low deformation rates in these areas. In this study, we conducted paleoseismological investigations along the southern Yangsan Fault (SYF), a typical low-deformation-rate fault, on the Korean Peninsula. The SYF is distinct from the northern Yangsan Fault (NYF), and the boundary between them is located at the junction between the NNE-striking YF and another major structure, the NNW-striking Ulsan Fault (UF), which branches off from the YF. Paleoseismological trenches at four sites along the SYF indicate that this fault section has not ruptured during the Holocene, in contrast to the NYF and UF. In detail, surface ruptures along the studied section of the SYF occurred during three different time periods, as inferred from stratigraphy and radiocarbon dating: 74 to 49 ka at two sites, 39 to 35 ka at another site, and 28,000 cal yr BP (or 30 ka considering the OSL age) to 16 ka at all sites. These results suggest two alternative rupture scenarios for the timing of paleoearthquakes along the studied fault section during the Late Pleistocene: (1) full rupture along the entire studied section during each earthquake event, or (2) multiple partial ruptures along the two structurally distinguishable parts of the studied fault section, that is, the Wolsan-Miho and Inbo north-Inbo sections. We conclude that geometric discontinuities of the longlived YF system in the Korean Peninsula intraplate region have played an important role in controlling recent spatiotemporal rupture behavior. | Kim, Taehyung; Choi, Jin-Hyuck; Cheon, Youngbeom; Lee, Tae-Ho; Kim, Namgwon; Lee, Hoil; Kim, Chang-Min; Choi, Yire; Bae, Hankyung; Kim, Young-Seog; Ryoo, Chung-Ryul; Klinger, Yann | Korea Inst Geosci & Mineral Resources, Act Tecton Res Ctr, Daejeon 34132, South Korea; Univ Sci & Technol, Geol Sci, Daejeon 34113, South Korea; Kyungpook Natl Univ, Sch Earth Syst Sci, Daegu 41566, South Korea; Kangwon Natl Univ, Dept Geol, Chunchon 24341, South Korea; Pukyong Natl Univ, Major Environm Geosci, Busan 48513, South Korea; Univ Paris Cite, CNRS, Inst Phys Globe Paris, Paris, France | LEE, HOIL/LJM-1919-2024; Lee, Tae-Ho/JMB-2371-2023; Kim, Young-Seog/AFP-0266-2022; klinger, yann/B-1226-2011; Kim, Sun/C-2026-2011 | 55763792550; 55511963900; 55357928100; 55656060100; 57218556086; 57204418236; 57191366440; 56701263100; 57204434749; 36065470500; 36895664500; 6602157334 | cheonyb@kigam.re.kr; | TECTONOPHYSICS | TECTONOPHYSICS | 0040-1951 | 1879-3266 | 854 | SCIE | GEOCHEMISTRY & GEOPHYSICS | 2023 | 2.7 | 30.2 | 4.27 | 2025-06-25 | 21 | 22 | Intraplate area; Southern Yangsan Fault; Rupture scenario; Partial rupture; Geometric discontinuity | SAN-ANDREAS FAULT; STRUCTURAL GEOLOGY; SE KOREA; GYEONGJU; ZONE; MECHANISM; DISPLACEMENT; DEFORMATION; TOPOGRAPHY; EXAMPLES | Geometric discontinuity; Intraplate area; Partial rupture; Rupture scenario; Southern Yangsan Fault | China; Yangshan; Zhejiang; Earthquakes; Fault slips; Strike-slip faults; Deformation rates; Fault sections; Geometric discontinuities; Intraplate area; Low deformations; Paleoearthquake; Partial rupture; Rupture scenario; Southern yangsan fault; Ulsan fault; correlation; deformation mechanism; earthquake catalogue; earthquake rupture; fault zone; intraplate process; paleoseismicity; strike-slip fault; Stratigraphy | English | 2023 | 2023-05-05 | 10.1016/j.tecto.2023.229817 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Investigating Hydrogenation of Aldehyde and Heck Reaction on the Surface of Recyclable Palladium Decorated Functionalized Mica | Palladium nanocrystals (Pd-NCs) were synthesized and immobilized on functionalized mica (Pd-NCs@FM). Pd-NCs@FM was used for catalyzing C-C coupling reaction. Preliminary, the activities of both palladium nanocubes/octahedra immobilized on functionalized mica (Pd-c@FM/Pd-o@FM) were investigated through probe reaction (hydrogenation of benzaldehyde: BzH). Probe reactions revealed that Pd-o@FM was highly active for hydrogenation of BzH to benzyl alcohol (BzOH) (yield: > 99% and selectivity > 96%). TEM images reflect uniform distribution of nanocrystals (NCs) on the surface of functionalized mica (FM) with approximate to 8% poly dispersity while SEM confirms smooth morphology of the catalyst. The average size of the NCs was 7-10 nm, while bulk particle size of Pd-NCs@FM was in the range 149-177 mu m. Surface area of FM and Pd-NCs@FM was 71+ and 59m(2)/g, respectively. The Pd-o@FM efficiently catalyzed Heck reaction of ethyl-benzimidazole acetate with bromobenzene to yield 99% isolated ethyl 2-(2-phenyl-1H -benzo [d]imidazole-1-yl) acetate. DFT study indicate that the ethyl-benzimidazole acetate (BZ) strongly anchored with the palladium decorated functionalized mica surface, evince the high catalytic activity of the catalyst. It was confirmed that Pd-NCs@FM can be effectively used for hydrogenation of aldehyde/ketone and C-C coupling reactions. | Sadiq, Muhammad; Choi, Sang-Il; Sadiq, Saima; Mahmood, Taskeen; Qazi, Sadia; Khan, Idrees; Iqbal, Zaffar; Aman, Razia | Univ Malakand, Dept Chem, Chakdara 18800, Pakistan; Kyungpook Natl Univ, Dept Chem, Daegu 41566, South Korea; Kyungpook Natl Univ, Green Nano Mat Res Ctr, Daegu 41566, South Korea; Kyungpook Natl Univ, Dept Chem, Daegu 41566, South Korea; Bacha Khan Univ, Dept Chem, Charsadda 24420, Pakistan | Sadiq, Saima/JAN-6421-2023; Choi, Sangil/N-7571-2013; Khan, Idrees/ABW-6018-2022; Sadiq, Muhammad/ABG-5017-2020 | 14627798100; 56167600800; 59029170800; 58181471000; 58181740800; 56124113300; 57212328466; 56926463900 | sadiq@uom.edu.pk; | ARABIAN JOURNAL FOR SCIENCE AND ENGINEERING | ARAB J SCI ENG | 2193-567X | 2191-4281 | 48 | 6 | SCIE | MULTIDISCIPLINARY SCIENCES | 2023 | 2.6 | 30.2 | 0.12 | 2025-06-25 | 1 | 1 | Palladium nanocrystals; Functionalized mica; Hydrogenation; Heck reaction; DFT | NANOPARTICLES; PD; CATALYSTS; 1,2-PROPANEDIOL; NANOCRYSTALS; OXIDATION; SHAPE; ACID | DFT; Functionalized mica; Heck reaction; Hydrogenation; Palladium nanocrystals | English | 2023 | 2023-06 | 10.1007/s13369-023-07828-3 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | A randomized, double-blind, controlled human study: The efficacy of exopolysaccharides in milk fermented by Weissella confusa VP30 (VP30-EPS) to ameliorate functional constipation | A randomized, double-blind, controlled human study was conducted to examine the effect of consuming exopolysaccharide (EPS) in milk fermented by Weissella confusa VP30 (VP30) on functional constipation. A total of 64 constipated adults, diagnosed by Rome III criteria for functional constipation, were randomized to receive either EPS-enriched VP30 fermented milk (VP30-EPS, n = 32) or an original VP30 fermented milk as a control fermented milk (CFM, n = 32) for 4 weeks. Questionnaires, which addressed defecation symptoms, dietary frequency and a dietary diary, were required to be completed every two weeks. Compared to the original VP30 fermented milk, EPS-enriched VP30 fermented milk was more effective in increasing defecation frequency, defecation volume, and fecal type during the 4-week treatment. The findings suggest that enrichment with EPS could improve indicators of bowel movement in individuals suffering from functional constipation. Constipation symptoms such as flatulence, pain, and bloating did not change to any statistically significant degree. The VP30EPS group exhibited a greater decrease in the sum of symptoms scores from baseline to 4th week than the CFM group, which was marginally significant (p = 0.059). Changes in ammonia production and short chain fatty acid content were not statistically significant. Gut microbiome analysis showed the proportion of Bacteroidetes in the VP30-EPS group increased slightly while Firmicutes in the VP30-EPS group decreased slightly and Prevotella increased. To the best of our knowledge, this is the first study that shows the functional effect of reducing functional constipation through human clinical studies by applying EPS produced by a Weissella strain to a fermented dairy food. | Jin, Hui; Park, Jiwon; Li, Rui; Ji, Geun Eog; V. Johnston, Tony; Choe, Deokyeong; Park, Se -Ho; Park, Myeong Soo; Ku, Seockmo | Seoul Natl Univ, Res Inst Human Ecol, Dept Food & Nutr, Seoul 08826, South Korea; Middle Tennessee State Univ, Coll Basic & Appl Sci, Sch Agr, Fermentat Sci Program, Murfreesboro, TN 37132 USA; Kyungpook Natl Univ, Coll Agr & Life Sci, Sch Food Sci & Biotechnol, Daegu 41566, South Korea; BIFIDO Co Ltd, Res Ctr, Hanam Si 12930, Gyeonggi Do, South Korea | ; Choe, Deokyeong/AAQ-1194-2020 | 57191821435; 58913339600; 57203738128; 7102392951; 57202011983; 37074453400; 57801796600; 7404490184; 37561670700 | jh1030@snu.ac.kr;chocobjw@naver.com;1766028931@qq.com;geji@snu.ac.kr;Tony.Johnston@mtsu.edu;cd02da@knu.ac.kr;p86ks1@bifido.com;bifidopark@bifido.com;Seockmo.ku@mtsu.edu; | JOURNAL OF FUNCTIONAL FOODS | J FUNCT FOODS | 1756-4646 | 2214-9414 | 104 | SCIE | FOOD SCIENCE & TECHNOLOGY;NUTRITION & DIETETICS | 2023 | 3.8 | 30.3 | 1.13 | 2025-06-25 | 7 | 7 | Constipation; Exopolysaccharide; EPS; Weissella confusa VP30; Probiotics | DIETARY FIBER INTAKE; LEUCONOSTOC-PSEUDOMESENTEROIDES; LAXATIVE USE; FLUID INTAKE; HUMAN FECES; DEXTRAN; ADULTS; CHILDREN; YOGURT; PURIFICATION | Constipation; EPS; Exopolysaccharide; Probiotics; Weissella confusa VP30 | English | 2023 | 2023-05 | 10.1016/j.jff.2023.105491 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Structures and digestibility of B-type high-amylose rice starches compared with A-type high-amylose rice starches | The starch structures and digestibility of starches prepared from newly developed Korean high amylose rice varieties were investigated. Amylose (AM) contents of Goami, Shingil, Goami 2, and Dodam starches were 25.56, 30.34, 36.33, and 45.78%, respectively. The Goami and Shingil starches were A-type crystallinity, while the Goami 2 and Dodam starches were B-type crystallinity. The molecular weights of AM were lower in the B-type starches (1.64 x 105 and 1.88 x 105) than in the A-type starches (3.88 x 105 and 3.00 x 105). The average chain length (CL) and longer branch CL (DP & GE; 25) of amylopectin (AP) were higher in B-type rice starches than in A-type rice starches. The ratio of 1045/1022 cm-1 and relative crystallinity were lower in the B-type rice starches. These results show that B-type starches have a higher AM content (>35%), gelatinization temperature, resistance to digestibility, and longer branch CL of AP, but a lower AM molecular weight than A-type starches. | No, Junhee; Shin, Malshick | Kyungpook Natl Univ, Dept Food & Nutr, 80 Daehak Ro, Daegu 41566, South Korea; Chonnam Natl Univ, Div Food & Nutr, 77 Yongbong Ro, Gwangju 61186, South Korea | 57188876908; 7401537566 | junheeno@knu.ac.kr;msshin@chonnam.ac.kr; | JOURNAL OF CEREAL SCIENCE | J CEREAL SCI | 0733-5210 | 1095-9963 | 112 | SCIE | FOOD SCIENCE & TECHNOLOGY | 2023 | 3.9 | 30.3 | 2.01 | 2025-06-25 | 13 | 15 | High amylose rice starch; B-type crystallinity; AM molecular weight; Japonica rice; Digestibility | PHYSICOCHEMICAL PROPERTIES; MOLECULAR-STRUCTURES; HIGH-QUALITY; GRANULES; MUTANT; ILPUMBYEO | AM molecular weight; B-type crystallinity; Digestibility; High amylose rice starch; Japonica rice | English | 2023 | 2023-07 | 10.1016/j.jcs.2023.103713 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Associations of Polyp Characteristics in Children and Adolescents Presenting with Less Than Five Colorectal Polyps: A Full Colonoscopy Is Still Required | Background/Aims: A full colonoscopy is currently required in children and adolescents with colorectal polyps, because of their potential of neoplastic transformation and complications such as intussusception. We aimed to analyze the associations of polyp characteristics in children and adolescents with colorectal polyps. Based on these findings, we also aimed to reevaluate the necessity of conducting a full colonoscopy.Methods: Pediatric patients <18 years of age who had undergone a colonoscopic polypectomy and those with <5 colorectal polyps were included in this multicenter, retrospective study. Baseline clinicodemographics, colonoscopic and histologic findings were investigated.Results: A total of 91 patients were included. Multivariate logistic regression analysis showed that polyp size was the only factor associated with the presence of any polyps located proximal to the splenic flexure (odds ratio [OR], 2.25; 95% confidence interval [CI], 1.28 to 4.28; p=0.007). Furthermore, polyp location proximal to the splenic flexure and sessile morphology were associated with the presence of any adenomatous polyp (OR, 8.51; 95% CI, 1.43 to 68.65; p=0.023; OR, 18.41; 95% CI, 3.45 to 173.81; p=0.002, respectively). Conclusions: In children and adolescents presenting with <5 colorectal polyps, polyp size and the presence of any adenomatous polyp were positively associated with polyp location proximal to the splenic flexure. This finding supports the necessity of a full colonoscopic exam in pediatric patients with colorectal polyps for the detection of polyps before the occurrence of complications such as intussusception or neoplastic transformation. (Gut Liver, Published online September 2, 2022) | Kim, Ju Young; Kim, Yu Bin; Choi, Sujin; Lee, Yoo Min; Kim, Hyun Jin; Kim, Soon Chul; Jang, Hyo-Jeong; Choi, So Yoon; Yi, Dae Yong; Lee, Yoon; Choi, You Jin; Kang, Yunkoo; Lee, Kyung Jae; Hong, Suk Jin; Hwang, Jun Hyun; Kwak, Sanggyu; Choe, Byung-Ho; Kang, Ben | Eulji Univ, Daejeon Eulji Med Ctr, Dept Pediat, Daejeon, South Korea; Ajou Univ Hosp, Dept Pediat, Suwon, South Korea; Kyungpook Natl Univ, Sch Med, Dept Pediat, Daegu, South Korea; Soonchunhyang Univ, Soonchunhyang Univ Bucheon Hosp, Dept Pediat, Coll Med, Bucheon, South Korea; Chungnam Natl Univ Hosp, Dept Pediat, Daejeon, South Korea; Jeonbuk Natl Univ, Jeonbuk Natl Univ Hosp, Dept Pediat, Med Sch, Jeonju, South Korea; Keimyung Univ, Keimyung Univ Dongsan Hosp, Dept Pediat, Sch Med, Daegu, South Korea; Kosin Univ, Kosin Univ Gospel Hosp, Dept Pediat, Coll Med, Pusan, South Korea; Chung Ang Univ, Chung Ang Univ Hosp, Dept Pediat, Coll Med, Seoul, South Korea; Korea Univ Anam Hosp, Dept Pediat, Seoul, South Korea; Inje Univ, Dept Pediat, Ilsan Paik Hosp, Goyang, South Korea; Yonsei Univ, Dept Pediat, Wonju Coll Med, Wonju, South Korea; Hallym Univ, Dept Pediat, Coll Med, Chunchon, South Korea; Daegu Catholic Univ, Dept Pediat, Sch Med, Daegu, South Korea; Daegu Catholic Univ Sch Med, Dept Prevent Med, Daegu, South Korea; Daegu Catholic Univ, Dept Med Stat, Sch Med, Daegu, South Korea | ; Lee, Yong Jae/GLR-4153-2022; Yi, Dae/G-1729-2014; Lee, Kyoungbun/F-6358-2011; Choe, Byung-Ho/KSM-6251-2024; Kim, Siwon/KHX-9078-2024; 康, 奔/JMQ-0812-2023; Kim, Ju/AAV-3029-2020 | 57202996384; 57212382905; 57223972405; 55588928200; 58975661600; 36087407700; 55355948500; 57207282105; 57190851975; 55588945800; 56063619400; 55607051000; 57022460500; 56573097000; 36129337200; 56645812600; 57574977300; 57194823199 | benkang@knu.ac.kr; | GUT AND LIVER | GUT LIVER | 1976-2283 | 2005-1212 | 17 | 3 | SCIE | GASTROENTEROLOGY & HEPATOLOGY | 2023 | 3.4 | 30.4 | 0.43 | 2025-06-25 | 2 | 3 | COLONIC POLYPS | Adenoma; Colonic polyps; Sessile; Size; Splenic flexure | Adenomatous Polyps; Adolescent; Child; Colonic Polyps; Colonoscopy; Colorectal Neoplasms; Humans; Intussusception; Retrospective Studies; adenomatous polyp; adolescent; Article; child; clinical feature; clinical practice; colonoscopy; colorectal polyp; confidence interval; cross-sectional study; demographics; disease association; female; histopathology; human; human tissue; major clinical study; male; multicenter study (topic); multivariate logistic regression analysis; odds ratio; preschool child; retrospective study; sessile polyp; splenic flexure; adenomatous polyp; clinical trial; colon polyp; colonoscopy; colorectal tumor; complication; intussusception; multicenter study | English | 2023 | 2023-05 | 10.5009/gnl210404 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Letter | Comments on Relationship between the High Fatty Liver Index and Risk of Fracture: Reply | Kim, Min-Ji; Roh, Jae-Hyung; Jeon, Jae-Han | Kyungpook Natl Univ, Sch Med, Chilgok Hosp, Dept Internal Med, Daegu, South Korea; Chungnam Natl Univ, Coll Med, Sejong Hosp, Dept Internal Med, Daejeon, South Korea | Kim, Min-Ji/Z-5205-2019 | 57206189095; 57216309871; 36910340400 | jeonjh@knu.ac.kr; | GUT AND LIVER | GUT LIVER | 1976-2283 | 2005-1212 | 17 | 4 | SCIE | GASTROENTEROLOGY & HEPATOLOGY | 2023 | 3.4 | 30.4 | 0 | 2025-06-25 | 0 | 0 | Humans; Non-alcoholic Fatty Liver Disease; Risk Factors; alcohol consumption; confidence interval; disease association; disease classification; disease exacerbation; disease predisposition; fatty liver index; fracture; fragility fracture; hazard ratio; human; incidence; Letter; nonalcoholic fatty liver; risk factor; complication; nonalcoholic fatty liver; risk factor | English | 2023 | 2023-07 | 10.5009/gnl230035 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||||
| ○ | ○ | Article | Comparison Trial between I-SCAN-Optical Enhancement and Chromoendoscopy for Evaluating the Horizontal Margins of Gastric Epithelial Neoplasms | Background/Aims: Endoscopic submucosal dissection is a widely used treatment for gastric epithelial neoplasms. Accurate delineation of the horizontal margins is necessary for the com-plete resection of gastric epithelial neoplasms. Recently, image-enhanced endoscopy has been used to evaluate horizontal margins of gastric epithelial neoplasms. The aim of this study was to investigate whether I-SCAN-optical enhancement (I-SCAN-OE) is superior to chromoendoscopy in evaluating the horizontal margin of gastric epithelial neoplasms. Methods: This was a multicenter, prospective, and randomized trial. The participants were divided into two groups: I-SCAN-OE and chromoendoscopy. For both groups, we first evaluated the hori-zontal margins of early gastric cancer or high-grade dysplasia using white-light imaging, and then evaluated, the horizontal margins using I-SCAN-OE or chromoendoscopy. We devised a unique scoring method based on the pathological results obtained after endoscopic submucosal dissec-tion to accurately evaluate the horizontal margins of gastric epithelial neoplasms. The delineation scores of both groups were compared, as were the ratios of positive/negative horizontal margins.Results: In total, 124 patients were evaluated for gastric epithelial neoplasms, of whom 112 were enrolled in the study. A total of 112 patients participated in the study, and 56 were assigned to each group (1:1). There was no statistically significant difference in the delineation scores be-tween the groups (chromoendoscopy, 7.80 +/- 1.94; I-SCAN-OE, 8.23 +/- 2.24; p=0.342).Conclusions: I-SCAN-OE did not show superiority over chromoendoscopy in delineating hori-zontal margins of gastric epithelial neoplasms. (Gut Liver, Published online November 1, 2022) | Koh, Myeongseok; Lee, Jong Yoon; Han, Song-Hee; Jeon, Seong Woo; Kim, Su Jin; Cho, Joo Young; Kim, Seong Hwan; Jang, Jae Young; Baik, Gwang Ho; Jang, Jin Seok | Dong A Univ, Dept Internal Med, Coll Med, Pusan, South Korea; Dong A Univ, Dept Pathol, Coll Med, Pusan, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Sch Med, Dept Internal Med, Daegu, South Korea; Pusan Natl Univ, Yangsan Hosp, Dept Internal Med, Coll Med, Yangsan, South Korea; CHA Univ, CHA Gumi Med Ctr, Dept Internal Med, Gumi, South Korea; Kyung Hee Univ, Coll Med, Dept Internal Med, Seoul, South Korea; Hallym Univ, Dept Internal Med, Coll Med, Chunchon, South Korea | Kim, Hwan-Cheol/GYR-0244-2022; Lee, Jong Yoon/HSH-6223-2023; Jang, Jae/AAN-1508-2020; CHO, JOO/AAJ-2012-2020; Jeon, Seongwoo/AAU-4618-2020; Kim, Sehyun/KDN-3343-2024 | 56519362200; 57215292973; 59604183800; 9733636500; 57201923992; 57216358471; 58848011600; 57215881098; 7801423477; 8444835300 | jsjang@dau.ac.kr; | GUT AND LIVER | GUT LIVER | 1976-2283 | 2005-1212 | 17 | 2 | SCIE | GASTROENTEROLOGY & HEPATOLOGY | 2023 | 3.4 | 30.4 | 0.71 | 2025-06-25 | 5 | 5 | Chromoendoscopy; Gastric cancer; Endoscopic submucosal dissection; Gastric neoplasm; Image-enhanced endoscopy | MAGNIFYING ENDOSCOPY; DIAGNOSIS; CANCER; EXTENT; MULTICENTER | Chromoendoscopy; Endoscopic submucosal dissection; Gastric cancer; Gastric neoplasm; Image-enhanced endoscopy | Carcinoma; Endoscopy, Gastrointestinal; Humans; Prospective Studies; Stomach Neoplasms; aged; Article; chromoendoscopy; controlled study; diagnostic accuracy; diagnostic test accuracy study; dysplasia; early gastric cancer; endoscopic submucosal dissection; endoscopy; female; gastric epithelial neoplasm; histopathology; human; human tissue; I SCAN optical enhancement; image enhancement; intermethod comparison; major clinical study; male; multicenter study; randomized controlled trial; stomach cancer; stomach tumor; surgical margin; carcinoma; clinical trial; diagnostic imaging; gastrointestinal endoscopy; pathology; procedures; prospective study; stomach tumor | English | 2023 | 2023-03 | 10.5009/gnl220025 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Current Practice Patterns of Endoscopic Ultrasound-Guided Tissue Sampling for Pancreatic Solid Mass in Korea: Outcomes of a National Survey | Background/Aims: Although endoscopic ultrasound (EUS)-guided fine needle aspiration (FNA) and fine needle biopsy (FNB) are widely used for tissue acquisition of pancreatic solid mass, the optimal strategy of this procedure has not been established yet. The aim of this nationwide study was to investigate the current practice patterns of EUS-FNA/FNB for pancreatic solid mass in Korea.Methods: The Policy-Quality Management of the Korean Pancreatobiliary Association (KPBA) developed a questionnaire containing 22 questions. An electronic survey consisting of the ques-tionnaire was distributed by e-mail to members registered to the KPBA.Results: A total of 101 respondents completed the survey. Eighty respondents (79.2%) performed preoperative EUS-FNA/FNB for operable pancreatic solid mass. Acquire needles (60.4%) were used the most, followed by ProCore needles (47.5%). In terms of need size, most respondents (>80%) preferred 22-gauge needles regardless of the location of the mass. Negative suction with a 10-mL syringe (71.3%) as sampling technique was followed by stylet slow-pull (41.6%). More than three needle passes for EUS-FNA/FNB was performed by most respondents (>80%). The frequency of requiring repeated procedure was significantly higher in respondents with a low individual volume (<5 per month, p=0.001). Prophylactic antibiotics were routinely used in 39 respondents (38.6%); rapid on-site pathologic evaluation was used in 6.1%.Conclusions: According to this survey, practices of EUS-FNA/FNB for pancreatic solid mass varied substantially, some of which differed considerably from the recommendations present in existing guidelines. These results suggest that the development of evidence-based quality guide-lines fitting Korean clinical practice is needed to establish the optimal strategy for this procedure.(Gut Liver, Published online September 5, 2022) | Ahn, Dong -Won; Chon, Hyung Ku; Moon, Sung-Hoon; Park, Sang Wook; Paik, Woo Hyun; Paik, Chang Nyol; Son, Byoung Kwan; Song, Tae Jun; Lee, Eaum Seok; Lee, Yun Nah; Lee, Yoon Suk; Lee, Jae Min; Jeon, Tae Joo; Park, Chang Hwan; Cho, Kwang Bum; Lee, Dong Wook; Kim, Hong Ja; Yoon, Seung Bae; Chung, Kwang Hyun; Park, Jin-Seok | Seoul Natl Univ, SMG SNU Boramae Med Ctr, Dept Internal Med, Coll Med, Seoul, South Korea; Wonkwang Univ, Dept Internal Med, Coll Med, Iksan, South Korea; Hallym Univ, Dept Internal Med, Coll Med, Anyang, South Korea; Kwangju Christian Hosp, Dept Internal Med, Gwangju, South Korea; Seoul Natl Univ, Coll Med, Dept Internal Med, Seoul Natl Univ Hosp, Seoul, South Korea; Catholic Univ Korea, St Vincents Hosp, Coll Med, Dept Internal Med, Seoul, South Korea; Eulji Univ, Uijeongbu Eulji Med Ctr, Dept Internal Med, Sch Med, Uijongbu, South Korea; Univ Ulsan, Dept Internal Med, Coll Med, Seoul, South Korea; Chungnam Natl Univ, Dept Internal Med, Coll Med, Daejeon, South Korea; Soonchunhyang Univ, Dept Internal Med, Sch Med, Bucheon, South Korea; Inje Univ, Ilsan Paik Hosp, Dept Internal Med, Coll Med, Goyang, South Korea; Korea Univ, Dept Internal Med, Coll Med, Seoul, South Korea; Inje Univ, Sanggye Paik Hosp, Dept Internal Med, Coll Med, Seoul, South Korea; Chonnam Natl Univ, Dept Internal Med, Med Sch, Gwangju, South Korea; Keimyung Univ, Dongsan Med Ctr, Dept Internal Med, Sch Med, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu, South Korea; Dankook Univ, Dept Internal Med, Coll Med, Cheonan, South Korea; Catholic Univ Korea, Coll Med, Dept Internal Med, Seoul, South Korea; Inha Univ, Dept Internal Med, Sch Med, Incheon, South Korea | Kim, Seong Cheol/ABD-1493-2022; Paik, Woo Hyun/B-9003-2016; Lee, Yun/J-1260-2014; Lee, Yoon Suk/D-1827-2019; Song, Taejun/JVZ-2733-2024; Paik, Woo/B-9003-2016; LEE, Yoon-Suk/D-1827-2019; Chon, Hyung ku/AGO-1334-2022 | 14022272100; 57191108189; 34870386900; 56864689800; 35822559900; 15058072500; 7007055567; 26028951400; 41461392000; 57129189700; 57219432560; 8636426500; 57217483767; 57207441931; 7403956834; 57202974895; 36684054600; 35217323900; 57217552216; 16241892100 | p1052ccy@hanmail.net;chokb@dsmc.or.kr; | GUT AND LIVER | GUT LIVER | 1976-2283 | 2005-1212 | 17 | 2 | SCIE | GASTROENTEROLOGY & HEPATOLOGY | 2023 | 3.4 | 30.4 | 0.29 | 2025-06-25 | 2 | 2 | Endoscopic ultrasound-guided fine needle aspiration; Pancreatic neoplasms; Sur-vey; Korea | FINE-NEEDLE-ASPIRATION; DIAGNOSTIC-ACCURACY; 25-GAUGE NEEDLES; EUS; 22-GAUGE; BIOPSY; ULTRASONOGRAPHY; SURVIVAL; CYTOLOGY; SOCIETY | Endoscopic ultrasound-guided fine needle aspiration; Korea; Pancreatic neoplasms; Survey | Endoscopic Ultrasound-Guided Fine Needle Aspiration; Endosonography; Humans; Pancreatic Neoplasms; Republic of Korea; Suction; antibiotic agent; Article; clinical practice; demographics; diagnostic procedure; e-mail; endoscopic ultrasound guided fine needle biopsy; human; human tissue; infection; infection prevention; Korea; pancreas tumor; questionnaire; sampling; suction; tumor localization; endoscopic ultrasonography; endoscopic ultrasound guided fine needle biopsy; pancreas tumor; pathology; procedures; South Korea | English | 2023 | 2023-03 | 10.5009/gnl220131 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Efficacy and Safety of Fexuprazan in Patients with Acute or Chronic Gastritis | Background/Aims: Fexuprazan is a novel potassium-competitive acid blocker that could be of benefit to patients with gastric mucosal injury. The aim of this study was to assess the 2-week efficacy and safety of fexuprazan in patients with acute or chronic gastritis. Methods: In this study, 327 patients with acute or chronic gastritis who had one or more gastric erosions on endoscopy and subjective symptoms were randomized into three groups receiving fexuprazan 20 mg once a day (q.d.), fexuprazan 10 mg twice a day (b.i.d.), or placebo for 2 weeks. The posttreatment assessments were the primary endpoint (erosion improvement rate), secondary endpoints (cure rates of erosion and edema and improvement rates of redness, hemorrhage, and subjective symptoms), and drug-related adverse events.Results: Among the patients, 57.8% (59/102), 65.7% (67/102), and 40.6% (39/96) showed erosion improvement 2 weeks after receiving fexuprazan 20 mg q.d., fexuprazan 10 mg b.i.d., and placebo, respectively. Both fexuprazan 20 mg q.d. and 10 mg b.i.d. showed superior efficacy to the placebo (p=0.017 and p<0.001, respectively). Likewise, both fexuprazan 20 mg q.d. and 10 mg b.i.d. also showed higher erosion healing rates than the placebo (p=0.033 and p=0.010, respectively). No difference was noted in the edema healing rate and the improvement rates for redness, hemorrhage, and subjective symptoms between the fexuprazan and placebo groups. No significant difference was noted in the incidence of adverse drug reactions.Conclusions: Fexuprazan 20 mg q.d. and 10 mg b.i.d. for 2 weeks showed therapeutic efficacy superior to that of placebo in patients with acute or chronic gastritis (ClinicalTrials.gov identifier NCT04341454). (Gut Liver, Published online February 15, 2023) | Ha Kim, Gwang; Choi, Myung-Gyu; Kim, Jin; Lee, Soo Teik; Chun, Hoon Jai; Lee, Kook Lae; Choi, Suk Chei; Jang, Jae-Young; Lee, Yong Chan; Kim, Jae Gyu; Kim, Ki Bae; Shim, Ki-Nam; Sohn, Chong; Kim, Sung Kook; Kim, Sang Gyun; Jang, Jin Seok; Kim, Nayoung; Jung, Hwoon-Yong; Park, Hyojin; Huh, Kyu Chan; Lee, Kwang Jae; Hong, Su Jin; Baek, Song; Han, Jin Joo; Lee, Oh Young | Pusan Natl Univ, Dept Internal Med, Biomed Res Inst, Coll Med, Busan, South Korea; Pusan Natl Univ Hosp, Biomed Res Inst, Busan, South Korea; Catholic Univ Korea, Seoul St Marys Hosp, Coll Med, Dept Internal Med, Seoul, South Korea; Catholic Univ Korea, Yeouido St Marys Hosp, Coll Med, Dept Internal Med, Seoul, South Korea; Jeonbuk Natl Univ Hosp, Dept Internal Med, Jeonju, South Korea; Korea Univ, Dept Internal Med, Anam Hosp, Seoul, South Korea; Seoul Natl Univ, SMG SNU Boramae Med Ctr, Dept Internal Med, Coll Med, Seoul, South Korea; Wonkwang Univ, Wonkwang Univ Hosp, Dept Internal Med, Coll Med, Iksan, South Korea; Kyung Hee Univ, Coll Med, Dept Gastroenterol & Hepatol, Seoul, South Korea; Yonsei Univ, Dept Internal Med, Coll Med, Seoul, South Korea; Chung Ang Univ, Dept Internal Med, Coll Med, Seoul, South Korea; Chungbuk Natl Univ, Chungbuk Natl Univ Hosp, Dept Internal Med, Coll Med, Cheongju, South Korea; Ewha Womans Univ, Dept Internal Med, Coll Med, Seoul, South Korea; Sungkyunkwan Univ, Kangbuk Samsung Hosp, Dept Internal Med, Sch Med, Seoul, South Korea; Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu, South Korea; Seoul Natl Univ, Dept Internal Med, Coll Med, Seoul, South Korea; Dong A Univ, Dept Internal Med, Coll Med, Busan, South Korea; Seoul Natl Univ, Seoul Natl Univ Coll Med, Dept Internal Med, Bundang Hosp, Seongnam, South Korea; Univ Ulsan, Asan Med Ctr, Dept Gastroenterol, Coll Med, Ulsan, South Korea; Yonsei Univ, Gangnam Severance Hosp, Dept Internal Med, Coll Med, Seoul, South Korea; Konyang Univ, Dept Internal Med, Div Gastroenterol, Coll Med, Daejeon, South Korea; Ajou Univ, Dept Gastroenterol, Sch Med, Suwon, South Korea; Soonchunhyang Univ, Dept Internal Med, Coll Med, Bucheon, South Korea; Daewoong Pharmaceut Co Ltd, Seoul, South Korea; Hanyang Univ, Coll Med, Dept Internal Med, Seoul, South Korea | ; Kim, Gwang Ha/ABF-3932-2021; Lee, Young/AAI-1932-2020; 김, 수중/JED-7162-2023; Kim, Sang/J-5398-2012; Lee, Hye/J-2154-2015; Lee, Jee-Yon/GER-4141-2022; Kwak, Sang Gyu/AAG-4341-2021; Choi, Myung-Gyu/D-6079-2014; Lee, Si/ABH-1408-2020; Kim, Ki Bae/KYQ-0127-2024; PARK, JUN-YOUNG/P-5981-2015; Kim, Nayoung/J-5387-2012 | 35214772400; 16635388700; 58252089900; 7601418502; 7202215162; 11239731700; 58700539400; 57215881098; 35264717600; 57486236700; 56106965700; 13604838300; 7102538401; 34770060400; 56371524600; 8444835300; 57201181440; 7403029804; 57317490400; 13003036700; 35345240300; 35285527200; 58700562800; 57195248356; 57252457600 | leeoy@hanyang.ac.kr; | GUT AND LIVER | GUT LIVER | 1976-2283 | 2005-1212 | 17 | 6 | SCIE | GASTROENTEROLOGY & HEPATOLOGY | 2023 | 3.4 | 30.4 | 1.29 | 2025-06-25 | 8 | 9 | Fexuprazan; Gastritis; Phase III clinical trial; Potassium-competitive acid blocker | HELICOBACTER-PYLORI; DOUBLE-BLIND; LANSOPRAZOLE; VONOPRAZAN | Fexuprazan; Gastritis; Phase III clinical trial; Potassium-competitive acid blocker | Amines; Double-Blind Method; Edema; Gastritis; Hemorrhage; Humans; Treatment Outcome; fexuprazan; placebo; amine; fexuprazan; abdominal distension; abdominal pain; acute gastritis; acute gastritis; adult; aged; Article; attributable risk; bleeding; blood examination; chronic gastritis; controlled study; defecation habit; diarrhea; double blind procedure; drug efficacy; drug safety; dyspepsia; edema; electrocardiography; endoscopy; female; gastritis; headache; human; hypertransaminasemia; Korea; leukopenia; major clinical study; male; medication compliance; multicenter study; phase 3 clinical trial; randomized controlled trial; somnolence; stomach erosion; urinalysis; urolithiasis; treatment outcome | English | 2023 | 2023-11 | 10.5009/gnl220457 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Efficacy and Safety of Infliximab in Intestinal Behcet's Disease: A Multicenter, Phase 3 Study (BEGIN) | Background/Aims: To date, there is no prospective study that specifically investigated the efficacy of infliximab in intestinal Behcet's disease (BD). This study evaluated the efficacy of infliximab in patients with moderate-to-severe active intestinal BD that are refractory to conventional therapies.Methods: This phase 3, interventional, open-label, single-arm study evaluated clinical outcomes of infliximab treatment in patients with moderate-to-severe intestinal BD. The coprimary endpoints were clinical response, decrease in disease activity index for intestinal BD (DAIBD) score >= 20 from weeks 0 to 8 for the induction therapy and week 32 for the maintenance therapy.Results: A total of 33 patients entered the induction therapy and were treated with infliximab 5 mg/kg intravenously at weeks 0, 2, and 6. The mean DAIBD score changed from 90.8 +/- 40.1 at week 0 to 40.3 +/- 36.4 at week 8, with a significant mean change of 50.5 +/- 36.4 (95% confidence interval, 37.5 to 63.4; p<0.001). Thirty-one (93.9%) continued to receive 5 mg/kg infliximab every 8 weeks during the maintenance therapy. The mean change in the DAIBD score after the maintenance therapy was statistically significant (61.5 +/- 38.5; 95% confidence interval, 46.0 to 77.1; p<0.001, from weeks 0 to 32). The proportion of patients who maintained a clinical response was 92.3% at week 32. No severe adverse reactions occurred during the induction and maintenance therapies.Conclusions: This study provided evidence that infliximab 5 mg/kg induction and maintenance therapies are efficacious and well-tolerated in patients with moderate-to-severe active intestinal BD. (ClinicalTrials.gov identifier: NCT02505568) (Gut Liver, Published online December 29, 2022) | Cheon, Jae Hee; Kim, Hyun-Soo; Han, Dong Soo; Kim, Sung Kook; Shin, Sung Jae; Kim, Joo Sung; Ye, Byong Duk; Song, Geun Am; Lee, YoungJa; Kim, Youngdoe; Lee, Yoosun; Kim, Won Ho | Yonsei Univ Coll Med, Inst Gastroenterol, Dept Internal Med, Seoul, South Korea; Yonsei Univ Wonju Coll Med, Dept Internal Med, Wonju, South Korea; Hanyang Univ Guri Hosp, Hanyang Univ Coll Med, Dept Internal Med, Seoul, South Korea; Kyungpook Natl Univ, Sch Med, Dept Internal Med, Div Gastroenterol, Daegu, South Korea; Ajou Univ Sch Med, Dept Gastroenterol, Suwon, South Korea; Seoul Natl Univ Coll Med, Dept Internal Med, Seoul, South Korea; Univ Ulsan Coll Med, Dept Gastroenterol, Seoul, South Korea; Pusan Natl Univ Sch Med, Dept Internal Med, Pusan, South Korea; Janssen Korea, Med Affairs, Seoul, South Korea | ; Cheon, Jae/B-4523-2015; Kim, Jung/D-3112-2015; Kwak, Sang Gyu/AAG-4341-2021; Kim, Sara/F-2951-2013; Kim, Won Ho/S-8671-2019; Cheon, Jae Hee/B-4523-2015; Han, Dong/P-1753-2015; Kim, Yong-Sik/J-5418-2012; Ye, Byong/AAF-4955-2020 | 35200350500; 55739553100; 14621423900; 34770060400; 57221641429; 7601375616; 14069472300; 56803090800; 57217094542; 57192809503; 58585808000; 57216285925 | geniushee@yuhs.ac;kimwonho@yuhs.ac; | GUT AND LIVER | GUT LIVER | 1976-2283 | 2005-1212 | 17 | 5 | SCIE | GASTROENTEROLOGY & HEPATOLOGY | 2023 | 3.4 | 30.4 | 0.71 | 2025-06-25 | 4 | 5 | Key Words; Infliximab; Tumor necrosis factor-alpha; Behcet syndrome; Intestinal diseases; Clinical efficacy | INFLAMMATORY-BOWEL; CROHNS-DISEASE; ADALIMUMAB; PROGNOSIS; UPDATE | Behcet syndrome; Clinical efficacy; Infliximab; Intestinal diseases; Tumor necrosis factor-alpha | Behcet Syndrome; Humans; Infliximab; Intestinal Diseases; Intestines; Prospective Studies; Treatment Outcome; aminosalicylic acid; azathioprine; infliximab; mercaptopurine; methotrexate; infliximab; abdominal pain; adult; angina pectoris; Article; asthenia; Behcet disease; breast cancer; clinical article; clinical assessment; clinical evaluation; Clostridium difficile infection; continuous infusion; controlled study; cystitis; disease activity score; disease severity; drug efficacy; drug safety; drug tolerance; dyspnea; evidence based practice; female; human; maintenance therapy; male; middle aged; multicenter study; onychomycosis; paresthesia; perianal abscess; phase 3 clinical trial; pruritus; rash; rhinopharyngitis; treatment duration; treatment outcome; treatment response; clinical trial; enteropathy; intestine; prospective study | English | 2023 | 2023-09 | 10.5009/gnl220278 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | External Validation of the eCura System for Undifferentiated-Type Early Gastric Cancer with Noncurative Endoscopic Resection | Background/Aims: The eCura system, a scoring model for stratifying the lymph node metastasis risk after noncurative endoscopic resection for early gastric cancer (EGC), has been internally validated, primarily for differentiated-type EGC. We aimed to externally validate this model for undifferentiated-type EGC.Methods: This multicenter, retrospective cohort study included 634 patients who underwent additional surgery (radical surgery group, n=270) or were followed up without additional treatment (no additional treatment group, n=364) after noncurative endoscopic resection for undifferentiated-type EGC between 2005 and 2015. The lymph node metastasis and survival rates were compared according to the risk categories.Results: For the radical surgery group, the lymph node metastasis rates were 2.6%, 10.9%, and 14.8% for the low-, intermediate-, and high-risk eCura categories, respectively (p for trend=0.003). For the low-, intermediate-, and high-risk categories in the no additional treatment group, the overall survival (92.7%, 68.9%, and 80.0% at 5 years, respectively, p<0.001) and cancer-specific survival rates (99.7%, 94.7%, and 80.0% at 5 years, respectively, p<0.001) differed significantly. In the multivariate analysis, the hazard ratios (95% confidence interval) in the no additional treatment group relative to the radical surgery group were 3.18 (1.41 to 7.17; p=0.005) for overall mortality and 2.60 (0.46 to 14.66; p=0.280) for cancer-specific mortality in the intermediate-tohigh risk category. No such differences were noted in the low-risk category.Conclusions: The eCura system can be applied to undifferentiated-type EGC. Close follow-up without additional treatment might be considered for low-risk patients, while additional surgery is recommended for intermediate- and high-risk patients. (Gut Liver, Published online May 10, 2023) | Yang, Hyo-Joon; Kim, Young-Il; Ahn, Ji Yong; Choi, Kee Don; Kim, Sang Gyun; Jeon, Seong Woo; Kim, Jie-Hyun; Shin, Sung Kwan; Lee, Hyuk; Lee, Wan Sik; Kim, Gwang Ha; Park, Jae Myung; Shin, Woon Geon; Choi, Il Ju | Sungkyunkwan Univ, Dept Internal Med, Div Gastroenterol, Sch Med, Seoul, South Korea; Sungkyunkwan Univ, Kangbuk Samsung Hosp, Gastrointestinal Canc Ctr, Sch Med, Seoul, South Korea; Res Inst & Hosp, Natl Canc Ctr, Ctr Gastr Canc, Goyang, South Korea; Univ Ulsan, Asan Med Ctr, Dept Gastroenterol, Coll Med, Ulsan, South Korea; Seoul Natl Univ, Dept Internal Med, Div Gastroenterol, Coll Med, Seoul, South Korea; Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu, South Korea; Seoul Natl Univ, Liver Res Inst, Coll Med, Seoul, South Korea; Yonsei Univ, Gangnam Severance Hosp, Inst Gastroenterol, Dept Internal Med,Coll Med, Seoul, South Korea; Yonsei Univ, Inst Gastroenterol, Dept Internal Med, Coll Med, Seoul, South Korea; Sungkyunkwan Univ, Samsung Med Ctr, Dept Med, Sch Med, Seoul, South Korea; Chonnam Natl Univ, Dept Internal Med, Med Sch, Gwangju, South Korea; Pusan Natl Univ, Dept Internal Med, Coll Med, Busan, South Korea; Pusan Natl Univ Hosp, Biomed Res Inst, Busan, South Korea; Catholic Univ Korea, Seoul St Marys Hosp, Coll Med, Dept Internal Med, Seoul, South Korea; Pusan Natl Univ Hosp, Biomed Res Inst, Dept Internal Med, Coll Med, Pusan, South Korea | Jeon, Seongwoo/AAU-4618-2020; Kim, Gwang Ha/ABF-3932-2021; Kim, Sang/J-5398-2012; LEE, KYUNG-HAN/HPD-9299-2023; Ahn, Ji Yong/AGO-1695-2022; Kim, Yuriy/ABD-7016-2020; Kim, Jie-Hyun/Q-9061-2019; Park, Jae Myung/AGK-6655-2022 | 57188930761; 57203809495; 36809017800; 14621577200; 56371524600; 9733636500; 49461401400; 57226038279; 57304930200; 57208140974; 35214772400; 8548758100; 13606883400; 7401471464 | cij1224@ncc.re.kr; | GUT AND LIVER | GUT LIVER | 1976-2283 | 2005-1212 | 17 | 4 | SCIE | GASTROENTEROLOGY & HEPATOLOGY | 2023 | 3.4 | 30.4 | 1.43 | 2025-06-25 | 12 | 10 | Stomach neoplasms; Undifferentiated-type histology; Endoscopic mucosal resec-tion; Lymphatic metastasis; Validation study | LYMPH-NODE METASTASIS; LONG-TERM OUTCOMES; SUBMUCOSAL DISSECTION; RISK-FACTORS; SURGERY; CRITERIA | Endoscopic mucosal resection; Lymphatic metastasis; Stomach neoplasms; Undifferentiated-type histology; Validation study | Early Detection of Cancer; Endoscopic Mucosal Resection; Gastrectomy; Gastric Mucosa; Humans; Lymphatic Metastasis; Proportional Hazards Models; Retrospective Studies; Risk Factors; Stomach Neoplasms; Treatment Outcome; adult; aged; all cause mortality; anaplastic carcinoma; Article; cancer mortality; cancer recurrence; cancer specific survival; cancer survival; confidence interval; controlled study; early cancer; eCura system; endoscopic mucosal resection; external validity; female; hazard ratio; high risk patient; human; intermediate risk patient; low risk patient; lymph node metastasis; major clinical study; male; middle aged; multivariate analysis; overall survival; retrospective study; risk factor; scoring system; stomach cancer; survival rate; treatment outcome; validation study; clinical trial; early cancer diagnosis; gastrectomy; lymph node metastasis; multicenter study; pathology; proportional hazards model; stomach mucosa; stomach tumor | English | 2023 | 2023-07 | 10.5009/gnl220333 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | Correction | External Validation of the eCura System for Undifferentiated-Type Early Gastric Cancer with Noncurative Endoscopic Resection (vol 17, pg 537, 2023) | Yang, Hyo-Joon; Kim, Young -Il; Ahn, Ji Yong; Choi, Kee Don; Kim, Sang Gyun; Jeon, Seong Woo; Kim, Jie-Hyun; Shin, Sung Kwan; Lee, Hyuk; Lee, Wan Sik; Ha Kim, Gwang; Park, Jae Myung; Shin, Woon Geon; Choi, Il Ju | Sungkyunkwan Univ, Kangbuk Samsung Hosp, Dept Internal Med, Div Gastroenterol,Sch Med, Seoul, South Korea; Sungkyunkwan Univ, Kangbuk Samsung Hosp, Gastrointestinal Canc Ctr, Sch Med, Seoul, South Korea; Natl Canc Ctr, Ctr Gastr Canc, Res Inst & Hosp, Goyang, South Korea; Univ Ulsan, Coll Med, Asan Med Ctr, Div Gastroenterol, Ulsan, South Korea; Seoul Natl Univ, Coll Med, Dept Internal Med, Div Gastroenterol, Seoul, South Korea; Seoul Natl Univ, Liver Res Inst, Coll Med, Seoul, South Korea; Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu, South Korea; Yonsei Univ, Coll Med, Gangnam Severance Hosp, Dept Internal Med,Inst Gastroenterol, Seoul, South Korea; Yonsei Univ, Coll Med, Inst Gastroenterol, Dept Internal Med, Seoul, South Korea; Sungkyunkwan Univ, Samsung Med Ctr, Sch Med, Dept Med, Seoul, South Korea; Chonnam Natl Univ, Med Sch, Dept Internal Med, Gwangju, South Korea; Pusan Natl Univ, Coll Med, Dept Internal Med, Busan, South Korea; Catholic Univ Korea, Coll Med, Seoul St Marys Hosp, Dept Internal Med, Seoul, South Korea; Hallym Univ, Coll Med, Inst Liver & Digest Dis, Dept Internal Med, Chunchon, South Korea | Kim, Sang/J-5398-2012; Ahn, Ji Yong/AGO-1695-2022; Kim, Gwang Ha/ABF-3932-2021; Jeon, Seongwoo/AAU-4618-2020; Park, Jae Myung/AGK-6655-2022; Kim, Jie-Hyun/Q-9061-2019 | GUT AND LIVER | GUT LIVER | 1976-2283 | 2005-1212 | 17 | 5 | SCIE | GASTROENTEROLOGY & HEPATOLOGY | 2023 | 3.4 | 30.4 | 0 | English | 2023 | 2023-09 | 10.5009/gnl220333.e | 바로가기 | 바로가기 | 바로가기 | |||||||||||||
| ○ | Review | Korean clinical practice guidelines on biologics and small molecules for moderate-to-severe ulcerative colitis | Ulcerative colitis (UC), a relapsing-remitting chronic inflammatory bowel disease (IBD), has a variable natural course but potentially severe disease course. Since the development of anti-tumor necrosis factor (TNF) agents has changed the natural disease course of moderate-to-severe UC, therapeutic options for patients who failed conventional treatments are expanding rapidly. IBD clinical trials have demonstrated the potential efficacy and safety of novel biologics such as anti-integrin α4β7 and anti-interleukin-12/23 monoclonal antibodies and small molecules such as a Janus kinase inhibitor. Anti-TNF biosimilars also have been approved and are widely used in IBD patients. Wise drug choices should be made considering evidence-based efficacy and safety. However, the best position of these drugs remains several questions, with limited data from direct comparative trials. In addition, there are still concerns to be elucidated on the effect of therapeutic drug monitoring and combination therapy with immunomodulators. The appropriate treatment regimens in acute severe UC and the risk of perioperative use of biologics are unclear. As novel biologics and small molecules have been approved in Korea, we present the Korean guidelines for medical management of adult outpatients with moderate-to-severe UC and adult hospitalized patients with acute severe UC, focusing on biologics and small molecules. (Intest Res 2023;21:61-87) © Copyright 2023. Korean Association for the Study of Intestinal Diseases | Na, Soo-Young; Choi, Chang Hwan; Song, Eun Mi; Bang, Ki Bae; Park, Sang Hyoung; Kim, Eun Soo; Park, Jae Jun; Keum, Bora; Lee, Chang Kyun; Lee, Bo-In; Ryoo, Seung-Bum; Koh, Seong-Joon; Choi, Miyoung; Kim, Joo Sung | Department of Internal Medicine, Incheon St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Incheon, South Korea; Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, South Korea; Department of Internal Medicine, Ewha Womans University School of Medicine, Seoul, South Korea; Department of Internal Medicine, Dankook University College of Medicine, Cheonan, South Korea; Department of Gastroenterology and Inflammatory Bowel Disease Center, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea; Department of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, South Korea; Department of Gastroenterology, Yonsei University College of Medicine, Seoul, South Korea; Department of Internal Medicine, Korea University College of Medicine, Seoul, South Korea; Department of Gastroenterology, College of Medicine, Kyung Hee University, Seoul, South Korea; Department of Internal Medicine, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea; Department of Surgery, Seoul National University College of Medicine, Seoul, South Korea; Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, South Korea; National Evidence-based Healthcare Collaborating Agency, Seoul, South Korea; Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, South Korea | 55682497900; 56799609000; 57193312165; 57204337211; 34977204700; 57203086704; 14120150500; 23094167700; 26434331200; 8623333800; 36115404700; 42061746300; 57129603200; 7601375616 | gicch@cau.ac.kr; | Intestinal Research | INTEST RES | 1598-9100 | 1598-9100 | 21 | 1 | ESCI | GASTROENTEROLOGY & HEPATOLOGY | 2023 | 3.4 | 30.4 | 4.05 | 2025-06-25 | 42 | Colitis; Guideline; Inflammatory bowel disease; Management; ulcerative | English | Final | 2023 | 10.5217/ir.2022.00007 | 바로가기 | 바로가기 | 바로가기 |
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