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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Article | Solvent Effects and pH Dependence of the X-ray Absorption Spectra of Proline from Electrostatic Embedding Quantum Mechanics/Molecular Mechanics and Mixed-Reference Spin-Flip Time-dependent Density-Functional Theory | The accurate description of solvent effects on X-ray absorption spectra (XAS) is fundamental for comparing the simulated spectra with experiments in solution. Currently, few protocols exist that can efficiently reproduce the effects of the solute/solvent interactions on XAS. Here, we develop an efficient and accurate theoretical protocol for simulating the solvent effects on XAS. The protocol combines electrostatic embedding QM/MM based on electrostatic potential fitted operators for describing the solute/solvent interactions and mixed-reference spin-flip time-dependent density functional theory (MRSF-TDDFT) for simulating accurate XAS spectra. To demonstrate the capabilities of our protocol, we compute the X-ray absorption of neutral proline in the gas phase and ionic proline in water in all relevant K-edges, showing excellent agreement with experiments. We show that states represented by core to pi* transitions are almost unaffected by the interaction with water, whereas the core to sigma* transitions are more impacted by the fluctuation of proline structure and the electrostatic interaction with the solvent. Finally, we reconstruct the pH-dependent XAS of proline in solution, determining that the N K-edge can be used to distinguish its three protonation states. | Alias-Rodriguez, Marc; Bonfrate, Simone; Park, Woojin; Ferre, Nicolas; Choi, Cheol Ho; Huix-Rotllant, Miquel | Aix Marseille Univ, CNRS, ICR, F-13013 Marseille, France; Kyungpook Natl Univ, Dept Chem, Daegu 41566, South Korea | ; Ferré, Nicolas/K-8228-2012; Huix-Rotllant, Miquel/J-3291-2016; Bonfrate, Simone/LSI-6399-2024; Ferre, Nicolas/K-8228-2012 | 57204724834; 57971754300; 57223952329; 7003305008; 7402958948; 25634188900 | marc.alias-rodriguez@univ-amu.fr;cchoi@knu.ac.kr;miquel.huix-rotllant@cnrs.fr; | JOURNAL OF PHYSICAL CHEMISTRY A | J PHYS CHEM A | 1089-5639 | 1520-5215 | 127 | 49 | SCIE | CHEMISTRY, PHYSICAL;PHYSICS, ATOMIC, MOLECULAR & CHEMICAL | 2023 | 2.7 | 28.7 | 0.95 | 2025-06-25 | 6 | 6 | ELECTRONIC-STRUCTURE; AMINO-ACIDS; SPECTROSCOPY; HYDRATION | Density functional theory; Embeddings; Molecular modeling; Quantum theory; Solvents; Water absorption; X ray absorption; proline; solvent; water; Embeddings; PH dependence; pH-dependence; Quantum mechanics/molecular mechanics; Simulated spectra; Solute-solvent interaction; Solvent effects; Spin flip time; Time dependent density functional theory; X-ray absorption spectrum; absorption; article; controlled study; density functional theory; ionization; molecular mechanics; pH; protonation; quantum mechanics; simulation; solute; solvent effect; static electricity; X ray; X ray analysis; Electrostatics | English | 2023 | 2023-11-29 | 10.1021/acs.jpca.3c05070 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Colorimetric Plasmonic Hydrogen Gas Sensor Based on One-Dimensional Nano-Gratings | Plasmonic hydrogen gas sensors have become widely used in recent years due to their low cost, reliability, safety, and measurement accuracy. In this paper, we designed, optimized, and fabricated a palladium (Pd)-coated nano-grating-based plasmonic hydrogen gas sensor; and investigated using the finite-difference time-domain method and experimental spectral reflectance measurements, the calibrated effects of hydrogen gas exposure on the mechano-optical properties of the Pd sensing layer. The nanostructures were fabricated using DC sputter deposition onto a one-dimensional nano-grating optimized with a thin-film gold buffer to extend the optical response dynamic range and performance stability; the color change sensitivity of the Pd surface layer was demonstrated for hydrogen gas concentrations as low as 0.5 vol.%, up to 4 vol.%, based on the resonance wavelength shift within the visible band corresponding to the reversible phase transformation. Visual color change detection of even the smallest hydrogen concentrations indicated the high sensitivity of the gas sensor. Our technique has potential for application to high-accuracy portable plasmonic sensors compatible with biochemical sensing with smartphones. | Zarei, Majid; Hamidi, Seyedeh M.; Chee, K. -W. -A. | Shahid Beheshti Univ, Laser & Plasma Res Inst, Magneto Plasmon Lab, Tehran 1983969411, Iran; Kyungpook Natl Univ, Natl Educ Ctr Semicond Technol, Daegu 41566, South Korea; Kyungpook Natl Univ, Inst Semicond Fus Technol, Daegu 41566, South Korea; Kyungpook Natl Univ, Dept Elect & Elect Engn, Daegu 41566, South Korea; Kyungpook Natl Univ, Coll IT Engn, Sch Elect Engn, Daegu 41566, South Korea | 57820341100; 23469366100; 57524559900 | m_hamidi@sbu.ac.ir;aghjuee@knu.ac.kr; | CRYSTALS | CRYSTALS | 2073-4352 | 13 | 2 | SCIE | CRYSTALLOGRAPHY;MATERIALS SCIENCE, MULTIDISCIPLINARY | 2023 | 2.4 | 28.8 | 0.65 | 2025-06-25 | 5 | 5 | lattice structure; phase change; plasmonic sensing; nano-gratings; thin films; surface plasmon resonance; polarization | LOW-COST; PD; ENERGY; RANGE; FILMS | lattice structure; nano-gratings; phase change; plasmonic sensing; polarization; surface plasmon resonance; thin films | English | 2023 | 2023-02 | 10.3390/cryst13020363 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Flame and heat transfer characteristics of a micro combustor with multihole baffle-induced inflows for a thermo-photovoltaic application | For an effective thermo-photovoltaic application, the inflow effects on the flame and heat transfer characteristics of micro power generators are numerically investigated in a multihole baffled micro combustor. The flow inside the baffle hole is considered as a circular pipe flow. Various inlet profiles of the micro combustor are obtained by varying the baffle thickness corresponding to the length of the baffle hole. The velocity distribution of the flow past the baffle plate attains an M-shaped (also called saddle-back), a parabolic, or a fully developed profile according to the baffle thickness. For a baffle thickness less than the fuel hole diameter, the inflow of the combustion chamber has an M-shaped velocity profile with two off-center peaks. Vortical motions and lobe-shaped flame are promoted by this type of inlet condition. Combustion characteristics, including flame length, combustion efficiency, heat loss ratio, and preheating effect, are comprehensively examined to evaluate the possibility as an thermo-photovoltaic device. The results indicate that a micro combustor with a thin baffle (b(t) <= 0.1D(f)) increases the combustion efficiency and wall heat flux. This suggests that the current baffled combustor can be effectively applied in both micro power generation systems and micro thermal emitters. | Kim, Won Hyun; Park, Tae Seon | Kyungpook Natl Univ, Sch Mech Engn, Daegu, South Korea; Kyungpook Natl Univ, Sch Mech Engn, 80 Daehak ro, Daegu 702701, South Korea | 55360608000; 7401801892 | tsparkjp@knu.ac.kr; | NUMERICAL HEAT TRANSFER PART A-APPLICATIONS | NUMER HEAT TR A-APPL | 1040-7782 | 1521-0634 | 84 | 6 | SCIE | MECHANICS;THERMODYNAMICS | 2023 | 2.8 | 28.8 | 0.18 | 2025-06-25 | 1 | 1 | Baffle thickness; flow recirculation; lobed shape flame; multihole baffled micro combustor; secondary flows; streamwise vortices; thermal efficiency | BLUFF-BODY SHAPE; STABILITY; EFFICIENCY; VORTICITY; SCHEMES; NOZZLE; FLOWS; WALL | Baffle thickness; flow recirculation; lobed shape flame; multihole baffled micro combustor; secondary flows; streamwise vortices; thermal efficiency | Combustors; Heat transfer; Photovoltaic effects; Thermal efficiency; Vortex flow; Baffle thickness; Flow recirculation; Heat-transfer characteristics; Lobed shape flame; Micro combustor; Multi holes; Multihole baffled micro combustor; Photovoltaic applications; Streamwise vortices; Thermal-efficiency; Heat flux | English | 2023 | 2023-09-17 | 10.1080/10407782.2022.2145395 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Bioactive Bone Substitute in a Rabbit Ulna Model: Preclinical Study | Background:Current therapies to effectively treat long-bone defects and extensive bone tissue loss remains limited. In this study, we created a new bone substitute by integrating advanced technologies such as structure patterning, controlled release of a bone growth factor and conjugation system for clinically effective bone regeneration. This novel bioactive bone substitute was evaluated for its safety and efficacy using a rabbit ulna model.Methods:A three dimensional bone patterned cylindrical structure with 1.5 cm in length and 5 mm in diameter was printed using poly(L-lactic acid)(PLLA) as a weight-bearing support and space-filling scaffold. And a bone morphogenetic protein 2 (BMP2) was employed to enhance bone regeneration, and coated to a 3D PLLA using alginate catechol and collagen to prolong the release kinetics. This novel bone substitute (BS)was evaluated for its physico-chemical and biological properties in vitro, and histological analysis and radiographical analysis such as X-ray, CT and micro-CT image analysis were performed to evaluate new bone formation in vivo.Results:The BS possesses an ideal shape and mechanically suitable proeperties for clinical use, with an easy-to-grab and break-resistant design at both ends, 80 +/- 10 MPa of compression strength, and BMP2 release for two months. Histological analysis demonstrated the biocompability of BS with minimal inflammation and immune response, and X-ray, CT and micro-CT demonstrated effective new bone formation in rabbit ulna defect model.Conclusion:The preclinical study of a novel bioactive bone substitute has shown its safe and effective properties in an animal model suggesting its clinical potential. | Hong, Yu Ri; Kim, Tae-Ho; Lee, Kyueui; Lim, Jeong Ok; Oh, Chang-Wug | Kyungpook Natl Univ Hosp, Biomed Res Inst BMRI, Daegu 41940, South Korea; Kyungpook Natl Univ, Sch Med, Daegu 41944, South Korea; Kyungpook Natl Univ, Joint Inst Regenerat Med, Daegu 41940, South Korea; Kyungpook Natl Univ, Dept Chem, Daegu 41566, South Korea; Kyungpook Natl Univ, Green Nano Mat Res Ctr, Daegu 41566, South Korea; Kyungpook Natl Univ Hosp, Dept Orthoped Surg, Daegu 41944, South Korea | Oh, Chang-Wug/AAO-4602-2021; Lee, Kyueui/ACR-8902-2022; Lee, Kyueui/P-8152-2018 | 58003346100; 57206927313; 56404800600; 7403454245; 22135834200 | jolim@knu.ac.kr;cwoh@knu.ac.kr; | TISSUE ENGINEERING AND REGENERATIVE MEDICINE | TISSUE ENG REGEN MED | 1738-2696 | 2212-5469 | 20 | 7 | SCIE | CELL & TISSUE ENGINEERING;ENGINEERING, BIOMEDICAL | 2023 | 4.4 | 28.9 | 0.91 | 2025-06-25 | 4 | 5 | Bone substitute; Controlled release; Bone morphogenetic protein 2; Poly-L-lactic acid | MORPHOGENETIC PROTEIN USE; DRUG-DELIVERY SYSTEMS; REGENERATION; SCAFFOLDS; SURGERY; REPAIR; RISK | Bone morphogenetic protein 2; Bone substitute; Controlled release; Poly-L-lactic acid | Animals; Bone Regeneration; Bone Substitutes; Rabbits; Tissue Scaffolds; Ulna; X-Ray Microtomography; Biocompatibility; Computerized tomography; Defects; Proteins; Scaffolds (biology); alginic acid; bone morphogenetic protein 2; catechol; collagen; growth factor; polylactic acid; Bioactive bone; Bone morphogenetic protein-2; Bone regeneration; Bone substitutes; Controlled release; Histological analysis; Micro CT; Poly-l-lactic acids; Preclinical studies; X-ray CT; Article; biological activity; bone development; bone regeneration; cell differentiation; controlled study; immune response; in vitro study; in vivo study; kinetics; Leporidae; male; micro-computed tomography; nonhuman; ossification; physical chemistry; preclinical study; safety; three dimensional printing; tissue structure; ulna; weight bearing; X ray; animal; chemistry; Leporidae; pathology; pharmacology; ulna; Lactic acid | English | 2023 | 2023-12 | 10.1007/s13770-023-00591-4 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | rhBMP-2-Conjugated Three-Dimensional-Printed Poly(l-lactide) Scaffold is an Effective Bone Substitute | BACKGROUND: Bone growth factors, particularly bone morphogenic protein-2 (BMP-2), are required for effective treatment of significant bone loss. Despite the extensive development of bone substitutes, much remains to be desired for wider application in clinical settings. The currently available bone substitutes cannot sustain prolonged BMP-2 release and are inconvenient to use. In this study, we developed a ready-to-use bone substitute by sequential conjugation of BMP to a three-dimensional (3D) poly(L-lactide) (PLLA) scaffold using novel molecular adhesive materials that reduced the operation time and sustained prolonged BMP release.METHODS:A 3D PLLA scaffold was printed and BMP-2 was conjugated with alginate-catechol and collagen. PLLA scaffolds were conjugated with different concentrations of BMP-2 and evaluated for bone regeneration in vitro and in vivo using a mouse calvarial model. The BMP-2 release kinetics were analyzed using ELISA. Histological analysis and micro-CT image analysis were performed to evaluate new bone formation.RESULTS: The 3D structure of the PLLA scaffold had a pore size of 400 mu m and grid thickness of 187-230 mu m. BMP-2 was released in an initial burst, followed by a sustained release for 14 days. Released BMP-2 maintained osteoinductivity in vitro and in vivo. Micro-computed tomography and histological findings demonstrate that the PLLA scaffold conjugated with 2 mu g/ml of BMP-2 induced optimal bone regeneration.CONCLUSION: The 3D-printed PLLA scaffold conjugated with BMP-2 enhanced bone regeneration, demonstrating its potential as a novel bone substitute. | Hong, Yu Ri; Kim, Tae-Ho; Park, Kyeong-Hyeon; Kang, Jumi; Lee, Kyueui; Park, Eui Kyun; Kwon, Tae-Geon; Lim, Jeong Ok; Oh, Chang-Wug | Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Joint Inst Regenerat Med, Biomed Res Inst, Daegu 41940, South Korea; Kyungpook Natl Univ, Sch Med, Daegu 41944, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Orthoped Surg, Daegu 41944, South Korea; Kyungpook Natl Univ, Green Nano Mat Res Ctr, Dept Chem, Daegu 41566, South Korea; Kyungpook Natl Univ, Sch Dent, Dept Oral Pathol & Regenerat Med, Daegu 41940, South Korea; Kyungpook Natl Univ, Sch Dent, Dept Oral & Maxillofacial Surg, Daegu 41940, South Korea | Lee, Kyueui/ACR-8902-2022; Oh, Chang-Wug/AAO-4602-2021; Lee, Kyueui/P-8152-2018; Park, KyeongHyeon/KEH-4919-2024 | 58003346100; 57206927313; 56969984400; 58003581400; 56404800600; 37071072400; 35205433300; 7403454245; 22135834200 | jolim@knu.ac.kr;cwoh@knu.ac.kr; | TISSUE ENGINEERING AND REGENERATIVE MEDICINE | TISSUE ENG REGEN MED | 1738-2696 | 2212-5469 | 20 | 1 | SCIE | CELL & TISSUE ENGINEERING;ENGINEERING, BIOMEDICAL | 2023 | 4.4 | 28.9 | 3.1 | 2025-06-25 | 16 | 17 | Bone regeneration; Bone morphogenetic protein 2; Printing; Three-dimensional; PLLA scaffold | MORPHOGENETIC PROTEIN-2; REGENERATION; DELIVERY; RHBMP-2; BIOACTIVITY; COLLAGEN; ACID | Bone morphogenetic protein 2; Bone regeneration; PLLA scaffold; Printing; Three-dimensional | Bone Regeneration; Bone Substitutes; Polyesters; X-Ray Microtomography; 3D printers; Adhesives; Computerized tomography; Proteins; Scaffolds (biology); adhesive agent; alginic acid; bone morphogenetic protein 2; collagen; pentobarbital; polylactide; recombinant bone morphogenetic protein 2; scaffold protein; polyester; polylactide; (3d) poly(L-lactide) scaffold; Bone growth; Bone morphogenetic protein-2; Bone morphogenic protein; Bone regeneration; Bone substitutes; In-vitro; Poly (l-lactide); rhBMP-2; Vitro and in vivo; animal cell; animal experiment; animal model; animal tissue; Article; bicinchoninic acid assay; bone regeneration; cell proliferation; computer assisted tomography; controlled study; cytotoxicity; enzyme linked immunosorbent assay; histology; immunohistochemistry; in vitro study; in vivo study; MC3T3-E1 cell line; micro-computed tomography; mouse; nonhuman; porosity; proton nuclear magnetic resonance; scanning electron microscopy; three dimensional printing; X ray; bone prosthesis; chemistry; pharmacology; Pore size | English | 2023 | 2023-02 | 10.1007/s13770-022-00506-9 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | The Efficacy and Safety of a Human Perirenal Adipose Tissue-Derived Stromal Vascular Fraction in an Interstitial Cystitis Rat Model | BACKGROUND: Interstitial cystitis (IC) is a chronic and intractable disease that can severely deteriorate patients' quality of life. Recently, stem cell therapy has been introduced as a promising alternative treatment for IC in animal models. We aimed to verify the efficacy and safety of the human perirenal adipose tissue-derived stromal vascular fraction (SVF) in an IC rat model.METHODS: From eight-week-old female rats, an IC rat model was established by subcutaneous injection of 200 lg of uroplakin3A. The SVF was injected into the bladder submucosal layer of IC rats, and pain scale analysis, awakening cytometry, and histological and gene analyses of the bladder were performed. For the in vivo safety analysis, genomic DNA purification and histological analysis were also performed to check tumorigenicity and thrombus formation.RESULTS: The mean pain scores in the SVF 20 ll group were significantly lower on days 7 and 14 than those in the control group, and bladder intercontraction intervals were significantly improved in the SVF groups in a dose-dependent manner. Regeneration of the bladder epithelium, basement membrane, and lamina propria was observed in the SVF group. In the SVF groups, however, bladder fibrosis and the expression of inflammatory markers were not significantly improved compared to those in the control group.CONCLUSION: This study demonstrated that a perirenal adipose tissue-derived SVF is a promising alternative for the management of IC in terms of improving bladder pain and overactivity. | Ha, Ji Yong; Lee, Eun Hye; Chun, So Young; Lee, Jun Nyung; Ha, Yun-Sok; Chung, Jae-Wook; Yoon, Bo Hyun; Jeon, Minji; Kim, Hyun Tae; Kwon, Tae Gyun; Yoo, Eun Sang; Kim, Bum Soo | Keimyung Univ Sch Med, Dongsan Med Ctr, Dept Urol, Daegu, South Korea; Kyungpook Natl Univ, Joint Inst Regenerat Med, Daegu, South Korea; Kyungpook Natl Univ Hosp, Biomed Res Inst, Daegu, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Urol, Daegu 41944, South Korea; Kyungpook Natl Univ, Chilgok Kyungpook Natl Univ Hosp, Sch Med, Dept Urol, Daegu, South Korea | Ha, Ji Yong/KSM-0577-2024; Kim, Soo-Yeon/ADR-9663-2022; Jeon, Minji/HTN-4703-2023 | 57640139900; 57189661699; 8688166900; 16301364600; 35487226400; 35204798500; 57218931150; 59026085100; 55739531300; 15073765400; 7006609239; 57202817150 | uroyoo@knu.ac.kr;urokbs@knu.ac.kr; | TISSUE ENGINEERING AND REGENERATIVE MEDICINE | TISSUE ENG REGEN MED | 1738-2696 | 2212-5469 | 20 | 2 | SCIE | CELL & TISSUE ENGINEERING;ENGINEERING, BIOMEDICAL | 2023 | 4.4 | 28.9 | 0.18 | 2025-06-25 | 1 | 1 | Interstitial cystitis; Animal model; Adipose tissue; Stem cell; Stromal vascular fraction | STEM-CELL THERAPY; BONE-MARROW; BLADDER; FAT | Adipose tissue; Animal model; Interstitial cystitis; Stem cell; Stromal vascular fraction | Adipose Tissue; Animals; Cystitis, Interstitial; Disease Models, Animal; Female; Humans; Pain; Quality of Life; Rats; Stromal Vascular Fraction; Integrated circuits; Rats; Tissue; interleukin 10; interleukin 17; interleukin 6; monocyte chemotactic protein 1; tiletamine plus zolazepam; toll like receptor 11; toll like receptor 2; tumor necrosis factor; uroplakin 3; Adipose tissue; Animal model; Control groups; Histological analysis; Interstitial cystiti; Interstitials; Rat model; Stem-cell; Stromal vascular fraction; Vascular fractions; abdominal injury; adipose tissue; animal experiment; animal model; animal tissue; Article; bladder epithelium; bladder intercontraction interval; carcinogenicity; cell infiltration; controlled study; cystometry; cytometry; DNA extraction; DNA purification; female; gene expression; histology; immunohistochemistry; in vivo study; interstitial cystitis; male; nonhuman; pain assessment; perirenal fat; polymerase chain reaction; quality of life; rat; stem cell; stromal vascular fraction; animal; disease model; human; interstitial cystitis; pain; Stem cells | English | 2023 | 2023-04 | 10.1007/s13770-022-00505-w | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Identification of the enantiomeric nature of 2-keto-3-deoxy-galactonate in the catabolic pathway of 3,6-anhydro-l-galactose | A novel metabolic pathway of 3,6-anhydro-l-galactose (l-AHG), the main sugar component in red macroalgae, was first discovered in the marine bacterium Vibrio sp. EJY3. l-AHG is converted to 2-keto-3-deoxy-galactonate (KDGal) in two metabolic steps. Here, we identified the enantiomeric nature of KDGal in the l-AHG catabolic pathway via stereospecific enzymatic reactions accompanying the biosynthesis of enantiopure l-KDGal and d-KDGal. Enantiopure l-KDGal and d-KDGal were synthesized by enzymatic reactions derived from the fungal galacturonate and bacterial oxidative galactose pathways, respectively. KDGal, which is involved in the l-AHG pathway, was also prepared. The results obtained from the reactions with an l-KDGal aldolase, specifically acting on l-KDGal, showed that KDGal in the l-AHG pathway exists in an l-enantiomeric form. Notably, we demonstrated the utilization of l-KDGal by Escherichia coli for the first time. E. coli cannot utilize l-KDGal as the sole carbon source. However, when a mixture of l-KDGal and d-galacturonate was used, E. coli utilized both. Our study suggests a stereoselective method to determine the absolute configuration of a compound. In addition, our results can be used to explore the novel l-KDGal catabolic pathway in E. coli and to construct an engineered microbial platform that assimilates l-AHG or l-KDGal as substrates. | Yun, Eun Ju; Yu, Sora; Kim, Dong Hyun; Park, Na Jung; Liu, Jing-Jing; Jin, Yong-Su; Kim, Kyoung Heon | Korea Univ, Coll Life Sci & Biotechnol, Grad Sch, Dept Biotechnol, Seoul 02841, South Korea; Univ Illinois, Carl R Woese Inst Genom Biol, Urbana, IL 61801 USA; Jeonbuk Natl Univ, Coll Environm & Bioresource Sci, Div Biotechnol, Iksan 54596, South Korea; Kyungpook Natl Univ, Sch Food Sci & Biotechnol, Daegu 41566, South Korea | Kim, Dong Hyun/LDT-2672-2024; Kim, Kyoung Heon/F-1059-2013; Kim, Kyoung/F-1059-2013; Jin, Yong-Su/L-4530-2013 | 57908444000; 56784670100; 55574224522; 57221397577; 56447155800; 57204009076; 34770896300 | ysjin@illinois.edu;khekim@korea.ac.kr; | APPLIED MICROBIOLOGY AND BIOTECHNOLOGY | APPL MICROBIOL BIOT | 0175-7598 | 1432-0614 | 107 | 24 | SCIE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | 2023 | 3.9 | 29.0 | 0.17 | 2025-06-25 | 1 | 1 | 2-Keto-3-deoxy-galactonate; 3,6-Anhydro-<sc>l</sc>-galactose; Red macroalgae; Stereospecificity; Enantiomer; Escherichia coli | GALACTONATE DEHYDRATASE; RED MACROALGAE; METABOLISM; CYCLOISOMERASE; AGAROSE; ENZYME | 2-Keto-3-deoxy-galactonate; 3,6-Anhydro-l-galactose; Enantiomer; Escherichia coli; Red macroalgae; Stereospecificity | Carbon; Escherichia coli; Galactose; Metabolic Networks and Pathways; Seaweed; Biochemistry; Carbon; Enantiomers; Metabolism; 2 keto 3 deoxy galactonate; 3,6 anhydro levo galactose; fructose bisphosphate aldolase; galactose; galacturonic acid; unclassified drug; carbon; galactose; 2-keto-3-deoxy-galactonate; 3,6-anhydro-l-galactose; Catabolic pathway; E. coli; Enantiomerics; Enzymatic reaction; Macro-algae; Red macroalga; Stereospecific; Stereospecificity; bacterium; chemical compound; coliform bacterium; enzyme; enzyme activity; red alga; Article; carbohydrate synthesis; carbon source; catabolism; controlled study; enantiomer; Escherichia coli; in vitro study; nonhuman; genetics; metabolism; seaweed; Escherichia coli | English | 2023 | 2023-12 | 10.1007/s00253-023-12807-7 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Urechistachykinin I induced ferroptosis by accumulating reactive oxygen species in Vibrio vulnificus | Antimicrobial peptides (AMPs), such as urechistachykinin I (LRQSQFVGSR-NH2), derived from urechis unicinctus, have demonstrated antimicrobial activities. It exhibits low cytotoxicity and selectivity between microbial and mammalian cells suggesting its potent antimicrobial ability. However, the underlying antimicrobial mechanisms remain unknown. Herein, we elucidated the antibacterial action against Vibrio vulnificus, focusing on the reactive oxygen species (ROS). ROS is crucial for antibiotic-mediated killing and oxidative stress. After treatment with urechistachykinin I, superoxide anions and hydroxyl radicals increase, and the overproduction of ROS leads to oxidative damage and destruction of the redox system. Oxidation of the defense system like glutathione or glutathione peroxidase 4 illustrates the dysfunction of cellular metabolism and induces lipid peroxidation attributed to depolarization and integrity brokerage. Cell death demonstrated these properties, and additional experiments, including iron accumulation, liperfluo, and DNA fragmentation, were promoted. The results demonstrated that urechistachykinin I-induced ferroptosis-like death in Vibrio vulnificus is dependent on ROS production. | Han, Giyeol; Lee, Dong Gun | Kyungpook Natl Univ, Sch Life Sci, BK 21 FOUR KNU Creat Biores Grp, Daegu 41566, South Korea | Lee, Dong-Gun/IWD-9833-2023 | 57363202000; 55668060900 | dglee222@knu.ac.kr; | APPLIED MICROBIOLOGY AND BIOTECHNOLOGY | APPL MICROBIOL BIOT | 0175-7598 | 1432-0614 | 107 | 24 | SCIE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | 2023 | 3.9 | 29.0 | 0 | 2025-06-25 | 0 | 0 | Antimicrobial peptides; Ferroptosis-like death; Reactive oxygen species; Vibrio vulnificus; Oxidative damage | LIPID-PEROXIDATION; ANTIMICROBIAL PEPTIDES; HYDROGEN-PEROXIDE; GLUTATHIONE; APOPTOSIS; QUANTIFICATION; NEUROPEPTIDES; MECHANISM | Antimicrobial peptides; Ferroptosis-like death; Oxidative damage; Reactive oxygen species; Vibrio vulnificus | Animals; Anti-Infective Agents; Ferroptosis; Mammals; Reactive Oxygen Species; Vibrio vulnificus; Bacteria; Cell death; Oxygen; Peptides; Redox reactions; glutathione; hydroxyl radical; phospholipid hydroperoxide glutathione peroxidase; polypeptide antibiotic agent; reactive oxygen metabolite; superoxide; antiinfective agent; reactive oxygen metabolite; urechistachykinin I; Anti-microbial activity; Antimicrobial peptide; Ferroptosis-like death; Low cytotoxicities; Mammalian cells; Microbial cells; Oxidative damage; Reactive oxygen species; Urechis unicinctus; Vibrio vulnificus; antimicrobial activity; bacterium; damage; DNA; lipid; metabolism; oxidative stress; reactive oxygen species; antibacterial activity; antimicrobial activity; Article; cell death; cell metabolism; controlled study; depolarization; destruction; DNA damage; DNA fragmentation; ferroptosis; gene overexpression; high performance liquid chromatography; lipid metabolism; lipid peroxidation; mass spectrometry; membrane potential; nonhuman; oxidation reduction reaction; oxidative stress; peroxidation; Vibrio vulnificus; animal; mammal; metabolism; Mammals | English | 2023 | 2023-12 | 10.1007/s00253-023-12802-y | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Exclusive π⁻ electroproduction off the neutron in deuterium in the resonance region | New results for the exclusive and quasifree cross sections off neutrons bound in deuterium gamma(v)n(p)-> p pi(-)(p) are presented over a wide final state hadron angle range with a kinematic coverage of the invariant mass (W) up to 1.825 GeV and the four-momentum transfer squared (Q(2)) from 0.4 to 1.0 GeV2. The exclusive structure functions were extracted and their Legendre moments were obtained. Final-state-interaction contributions have been kinematically separated from the extracted quasifree cross sections off bound neutrons solely based on the analysis of the experimental data. These new results will serve as long-awaited input for phenomenological analyses to extract the Q(2) evolution of previously unavailable n -> N* electroexcitation amplitudes and to improve state-of-the-art models of neutrino scattering off nuclei by augmenting the already available results from free protons. | Tian, Y.; Gothe, R. W.; Mokeev, V., I; Hollis, G.; Amaryan, M. J.; Armstrong, W. R.; Atac, H.; Avakian, H.; Barion, L.; Battaglieri, M.; Bedlinskiy, I; Benkel, B.; Benmokhtar, F.; Bianconi, A.; Biondo, L.; Biselli, A.; Bossu, F.; Boiarinov, S.; Bondi, M.; Brinkmann, K. T.; Briscoe, W. J.; Bueltmann, S.; Bulumulla, D.; Burkert, V. D.; Capobianco, R.; Carman, D. S.; Carvajal, J. C.; Celentano, A.; Chesnokov, V; Chetry, T.; Ciullo, G.; Clash, G.; Cole, P. L.; Contalbrigo, M.; Costantini, G.; D'Angelo, A.; Dashyan, N.; De Vita, R.; Defurne, M.; Deur, A.; Diehl, S.; Djalali, C.; Dupre, R.; Egiyan, H.; El Alaoui, A.; El Fassi, L.; Elouadrhiri, L.; Eugenio, P.; Fegan, S.; Filippi, A.; Gavalian, G.; Gilfoyle, G. P.; Girod, F. X.; Golubenko, A. A.; Gosta, G.; Griffioen, K.; Guidal, M.; Hakobyan, H.; Hattawy, M.; Hayward, T. B.; Hobart, A.; Holtrop, M.; Ilieva, Y.; Ireland, D. G.; Isupov, E. L.; Jenkins, D.; Jo, H. S.; Joo, K.; Joosten, S.; Keller, D.; Khanal, A.; Khandaker, M.; Kim, A.; Kim, W.; Klein, F. J.; Kripko, A.; Kubarovsky, V; Lagerquist, V; Lanza, L.; Leali, M.; Lenisa, P.; Livingston, K.; MacGregor, I. J. D.; Marchand, D.; Marsicano, L.; Mascagna, V; McKinnon, B.; Migliorati, S.; Mineeva, T.; Mirazita, M.; Camacho, C. Munoz; Nadel-Turonski, P.; Naidoo, P.; Neupane, K.; Newton, J.; Niccolai, S.; Nicol, M.; Niculescu, G.; Osipenko, M.; Pandey, P.; Paolone, M.; Pappalardo, L. L.; Paremuzyan, R.; Park, K.; Pasyuk, E.; Paul, S. J.; Phelps, W.; Pilleux, N.; Pocanic, D.; Pogorelko, O.; Poudel, J.; Price, J. W.; Prok, Y.; Reed, T.; Ripani, M.; Ritman, J.; Rizzo, A.; Rosner, G.; Sabatie, F.; Salgado, C.; Schadmand, S.; Schmidt, A.; Schumacher, R. A.; Shirokov, E., V; Shrestha, U.; Simmerling, P.; Sokhan, D.; Sparveris, N.; Stepanyan, S.; Strakovsky, I. I.; Strauch, S.; Tyson, R.; Ungaro, M.; Venturelli, L.; Voskanyan, H.; Voutier, E.; Watts, D. P.; Wei, K.; Wei, X.; Wood, M. H.; Yale, B.; Zachariou, N.; Zhang, J. | Univ South Carolina, Columbia, SC 29208 USA; Syracuse Univ, Syracuse, NY 13244 USA; Thomas Jefferson Natl Accelerator Facil, Newport News, VA 23606 USA; Old Dominion Univ, Norfolk, VA 23529 USA; Argonne Natl Lab, Argonne, IL 60439 USA; Temple Univ, Philadelphia, PA 19122 USA; Ist Nazl Fis Nucl, Sez Ferrara, I-44100 Ferrara, Italy; Ist Nazl Fis Nucl, Sez Genova, I-16146 Genoa, Italy; Natl Res Ctr Kurchatov Inst ITEP, Moscow 117259, Russia; Univ Tecn Federico Santa Maria, Casilla 110-V, Valparaiso, Chile; Duquesne Univ, 600 Forbes Ave, Pittsburgh, PA 15282 USA; Univ Brescia, I-25123 Brescia, Italy; Ist Nazl Fis Nucl, Sez Pavia, I-27100 Pavia, Italy; Ist Nazl Fis Nucl, Sez Catania, I-95123 Catania, Italy; Univ Messina, I-98166 Messina, Italy; Fairfield Univ, 1073 North Benson Rd, Fairfield, CT 06824 USA; Univ Paris Saclay, CEA, IRFU, F-91191 Gif Sur Yvette, France; Ist Nazl Fis Nucl, Sez Roma Tor Vergata, I-00133 Rome, Italy; Univ Roma Tor Vergata, I-00133 Rome, Italy; Univ Giefien, Phys Inst 2, D-35392 Giefien, Germany; GSI Helmholtzzentrum Schwerionenforsch, Helmholtz Forschungsakad Hessen FAIR HFHF, Campus Giessen, D-35392 Giessen, Germany; George Washington Univ, Washington, DC 20052 USA; Univ Connecticut, Storrs, CT 06269 USA; Florida Int Univ, Miami, FL 33199 USA; Lomonosov Moscow State Univ, Skobeltsyn Inst Nucl Phys, Moscow 119234, Russia; Lomonosov Moscow State Univ, Phys Dept, Moscow 119234, Russia; Mississippi State Univ, Mississippi State, MS 39762 USA; Univ Ferrara, I-44121 Ferrara, Italy; Univ York, York YO10 5DD, N Yorkshire, England; Lamar Univ, 4400 MLK Blvd,POB 10046, Beaumont, TX 77710 USA; Yerevan Phys Inst, Yerevan 375036, Armenia; Ohio Univ, Athens, OH 45701 USA; Univ Paris Saclay, IJCLab, CNRS IN2P3, F-91405 Orsay, France; Florida State Univ, Tallahassee, FL 32306 USA; Ist Nazl Fis Nucl, Sez Torino, I-10125 Turin, Italy; Univ New Hampshire, Durham, NH 03824 USA; Univ Richmond, Richmond, VA 23173 USA; Coll William & Mary, Williamsburg, VA 23187 USA; Univ Glasgow, Glasgow G12 8QQ, Lanark, Scotland; Virginia Tech, Blacksburg, VA 24061 USA; Kyungpook Natl Univ, Daegu 41566, South Korea; Univ Virginia, Charlottesville, VA 22901 USA; Norfolk State Univ, Norfolk, VA 23504 USA; Catholic Univ Amer, Washington, DC 20064 USA; Rensselaer Polytech Inst, New York, NY 12180 USA; Ist Nazl Fis Nucl, Lab Nazl Frascati, I-00044 Frascati, Italy; James Madison Univ, Harrisonburg, VA 22807 USA; New Mexico State Univ, POB 30001, Las Cruces, NM 88003 USA; Univ Calif Riverside, 900 Univ Ave, Riverside, CA 92521 USA; Christopher Newport Univ, Newport News, VA 23606 USA; Calif State Univ, Dominguez Hills, Carson, CA 90747 USA; GSI Helmholtzzentrum Schwerionenforsch GmbH, D-64291 Darmstadt, Germany; Carnegie Mellon Univ, Pittsburgh, PA 15213 USA; Canisius Coll, Buffalo, NY 14208 USA | Hakobyan, Hayk/JUF-6461-2023; Ireland, David/E-8618-2010; Sabatie, Franck/K-9066-2015; Pappalardo, Luciano/AAB-2380-2021; Mascagna, Valerio/HLQ-1103-2023; Khanal, Aaditya/ABI-5610-2020; POUDEL, JIWAN/KQU-6557-2024; Bozzi, Giuseppe/H-7283-2017; Tian, Ye/LJL-9027-2024; Hyde, Charles/W-9190-2018; Zhang, Jixie/A-1461-2016; Osipenko, Mikhail/N-8292-2015; McKinnon, Bryan/J-2928-2018; Mineeva, Taisiya/MDT-1592-2025; Deur, Alexandre/H-9778-2019; Jo, Hyon-Suk/HGC-7070-2022; Lanza, Lucilla/E-6479-2017; Holtrop, Maurik/A-9017-2010; Alaoui, Ahmed/B-4638-2015; Tyson, Richard/LRC-4125-2024; MacGregor, Ian/D-4072-2011; Sparveris, Nikolaos/C-4751-2008; D'Angelo, Annalisa/A-2439-2012; Adikaram, Dasuni/D-1539-2016; Burkert, Volker/AAF-7395-2020; Marsicano, Luca/KPB-4594-2024; Isupov, Evgeny/J-2976-2012; Celentano, Andrea/JFJ-2728-2023; Battaglieri, Marco/I-6262-2018; Schumacher, Reinhard/K-6455-2013; Joosten, Sylvester/HZL-4182-2023; Costantini, Giulio/F-3829-2018 | 55154774200; 7102183142; 7004546205; 57193732799; 35277104000; 57221249616; 57210826461; 7006613415; 23033257000; 7004520678; 35277104100; 57605743600; 57218527298; 7102358422; 57226649056; 35227021700; 35725064700; 35277071300; 54398256600; 7007041327; 7005532059; 57203690067; 57218357843; 7004440244; 57221140443; 7005853901; 57214364802; 54392656300; 26663235200; 57189889203; 6603765308; 57221141185; 35227101500; 7003468594; 57221147612; 55828029600; 6507987909; 59345445900; 56272524200; 6604025441; 57217562965; 35374416600; 35069234100; 35227171500; 26535686800; 14041647600; 35227171600; 9845148400; 56978985100; 8695796100; 35227304900; 6603686320; 35227280900; 57210932456; 56711891800; 57217000308; 7003432409; 57208726428; 56115055200; 57206656408; 57214681432; 7005060869; 35227424100; 7006927902; 35227460400; 57237808500; 35227429400; 57202638465; 23034837300; 57216594895; 57208691543; 13405022500; 36604596000; 35227558900; 57251793200; 57205462419; 6701392158; 57200223336; 56047689500; 6507646370; 56273696800; 9278396500; 7006040977; 7004889588; 57193833269; 22135531000; 35227669300; 57224626542; 26023453000; 35227656900; 12244632700; 6603294089; 57214093211; 57212715831; 56530113800; 35227746500; 57221141731; 35227763200; 6701825145; 57226647977; 22986163400; 7004207376; 36085149700; 55722196400; 35227791700; 57208699533; 56362788600; 57385323900; 6701538888; 8903140900; 57200602864; 55329126900; 35227871000; 57219768156; 7003515879; 6701495633; 56589489300; 7102538331; 35227896300; 35228024200; 57208791396; 57212416423; 7201653195; 15030349100; 57213706614; 57217309320; 16065283100; 6507906118; 7004491103; 22969481600; 7004321986; 57222078258; 35228099400; 22136651400; 6504161736; 6603350317; 7201539565; 57221067333; 13204321200; 57201559118; 57204955185; 36836386600; 57215210642 | yetian@syr.edu; | PHYSICAL REVIEW C | PHYS REV C | 2469-9985 | 2469-9993 | 107 | 1 | SCIE | PHYSICS, NUCLEAR | 2023 | 3.2 | 29.5 | 0.14 | 2025-06-25 | 1 | 1 | CHARGED PIONS; NUCLEON; PROTON | English | 2023 | 2023-01-05 | 10.1103/physrevc.107.015201 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Observation of large missing-momentum (e, e'p) cross-section scaling and the onset of correlated-pair dominance in nuclei | We report the measurement of x(B) scaling in (e, e'p) cross-section ratios off nuclei relative to deuterium at large missing momentum of 350 375 MeV/c), suggesting the observed scaling results from interacting with nucleons in short-range correlated (SRC) pairs. For low missing momenta, mean-field calculations show good agreement with the data for p(miss) < k(F), and suggest a potential non-negligible contribution to the measured cross-section ratios from scattering off single, uncorrelated, nucleons up to p(miss) approximate to 350 MeV/c. Therefore, SRCs become dominant in nuclei at p(miss) approximate to 350 MeV/c, well above the nuclear Fermi Surface of k(F) approximate to 250 MeV/c. | Korover, I.; Denniston, A. W.; Kiral, A.; Schmidt, A.; Lovato, A.; Rocco, N.; Nikolakopoulos, A.; Weinstein, L. B.; Piasetzky, E.; Hen, O.; Amaryan, M. J.; Angelini, Giovanni; Atac, H.; Baltzell, N. A.; Barion, L.; Battaglieri, M.; Bedlinskiy, I.; Benmokhtar, Fatiha; Bianconi, A.; Biondo, L.; Biselli, A. S.; Bossu, F.; Boiarinov, S.; Briscoe, W. J.; Bulumulla, D.; Burkert, V. D.; Carman, D. S.; Carvajal, J. C.; Caudron, M.; Chatagnon, P.; Chetry, T.; Ciullo, G.; Clark, L.; Cole, P. L.; Contalbrigo, M.; Costantini, G.; D'Angelo, A.; Dashyan, N.; De Vita, R.; Defurne, M.; Deur, A.; Diehl, S.; Djalali, C.; Duer, M.; Dupre, R.; Egiyan, H.; Ehrhart, M.; El Alaoui, A.; El Fassi, L.; Elouadrhiri, L.; Eugenio, P.; Fegan, S.; Fersch, R.; Filippi, A.; Gavalian, G.; Ghandilyan, Y.; Gilfoyle, G. P.; Girod, F. X.; Golubenko, A. A.; Gothe, R. W.; Griffioen, K. A.; Guidal, M.; Guo, L.; Hafidi, K.; Hakobyan, H.; Hattawy, M.; Hayward, T. B.; Heddle, D.; Hicks, K.; Hobart, A.; Holtrop, M.; Hyde, C. E.; Ilieva, Y.; Ireland, D. G.; Isupov, E. L.; Jo, H. S.; Joo, K.; Joosten, S.; Keller, D.; Khanal, A.; Khandaker, M.; Kim, A.; Kim, W.; Kripko, A.; Kubarovsky, V.; Lanza, L.; Leali, M.; Lenisa, P.; Livingston, K.; MacGregor, I. J. D.; Marchand, D.; Marsicano, L.; Mascagna, V.; McKinnon, B.; Migliorati, S.; Mirazita, M.; Mokeev, V.; Camacho, C. Munoz; Nadel-Turonski, P.; Neupane, K.; Niccolai, S.; Niculescu, G.; O'Connell, T. R.; Osipenko, M.; Ostrovidov, A. I.; Pandey, P.; Paolone, M.; Pappalardo, L. L.; Paremuzyan, R.; Pasyuk, E.; Pogorelko, O.; Pokhrel, M.; Poudel, J.; Price, J. W.; Prok, Y.; Raue, B. A.; Reed, Trevor; Ripani, M.; Ritman, J.; Rizzo, A.; Rosner, G.; Rossi, P.; Rowley, J.; Sabatie, F.; Schumacher, R. A.; Segarra, E. P.; Sharabian, Y. G.; Shirokov, E., V; Shrestha, U.; Soto, O.; Sparveris, N.; Stepanyan, S.; Strakovsky, I. I.; Strauch, S.; Tyson, R.; Ungaro, M.; Venturelli, L.; Voskanyan, H.; Vossen, A.; Voutier, E.; Wei, Kevin; Wei, X.; Wishart, R.; Wood, M. H.; Yale, B.; Zachariou, N.; Zhang, J.; Zhao, Z. W. | MIT, Cambridge, MA 02139 USA; Tel Aviv Univ, Sch Phys & Astron, IL-69978 Tel Aviv, Israel; George Washington Univ, Washington, DC 20052 USA; Old Dominion Univ, Norfolk, VA 23529 USA; Thomas Jefferson Natl Accelerator Facil, Newport News, VA 23606 USA; Argonne Natl Lab, Div Phys, Lemont, IL 60439 USA; Fermilab Natl Accelerator Lab, Dept Theoret Phys, POB 500, Batavia, IL 60510 USA; Calif State Univ, Dominguez Hills, Carson, CA 90747 USA; Canisius Coll, Buffalo, NY USA; Carnegie Mellon Univ, Pittsburgh, PA 15213 USA; Catholic Univ Amer, Washington, DC 20064 USA; Univ Paris Saclay, IRFU, CEA, F-91191 Gif Sur Yvette, France; Christopher Newport Univ, Newport News, VA 23606 USA; Univ Connecticut, Storrs, CT 06269 USA; Duke Univ, Durham, NC 27708 USA; Duquesne Univ, 600 Forbes Ave, Pittsburgh, PA 15282 USA; Fairfield Univ, Fairfield, CT 06824 USA; Univ Ferrara, I-44121 Ferrara, Italy; Florida Int Univ, Miami, FL 33199 USA; Florida State Univ, Tallahassee, FL 32306 USA; INFN, Sez Ferrara, I-44100 Ferrara, Italy; INFN, Lab Naz Frascati, I-00044 Frascati, Italy; INFN, Sez Genova, I-16146 Genoa, Italy; INFN, Sez Roma Tor Vergata, I-00133 Rome, Italy; INFN, Sez Torino, I-10125 Turin, Italy; INFN, Sez Catania, I-95123 Catania, Italy; INFN, Sez Pavia, I-27100 Pavia, Italy; Univ Paris Saclay, IJCLab, CNRS, IN2P3, F-91405 Orsay, France; Inst Kernphys Julich, Julich, Germany; James Madison Univ, Harrisonburg, VA 22807 USA; Kyungpook Natl Univ, Daegu 41566, South Korea; Lamar Univ, 4400 MLK Blvd,POB 10046, Beaumont, TX 77710 USA; Mississippi State Univ, Mississippi State, MS 39762 USA; Natl Res Ctr Kurchatov Inst ITEP, Moscow 117259, Russia; Univ New Hampshire, Durham, NH 03824 USA; New Mexico State Univ, POB 30001, Las Cruces, NM 88003 USA; Norfolk State Univ, Norfolk, VA 23504 USA; Ohio Univ, Athens, OH 45701 USA; II Phys Inst Univ Giessen, D-35392 Giessen, Germany; Rensselaer Polytech Inst, Troy, NY 12180 USA; Univ Richmond, Richmond, VA 23173 USA; Univ Roma Tor Vergata, I-00133 Rome, Italy; Lomonosov Moscow State Univ, Inst Nucl Phys, Moscow 119234, Russia; Univ South Carolina, Columbia, SC 29208 USA; Temple Univ, Philadelphia, PA 19122 USA; Univ Tecn Federico Santa Maria, Casilla 110-5, Valparaiso, Chile; Univ Insubria, I-22100 Como, Italy; Univ Brescia, I-25123 Brescia, Italy; Univ Messina, I-98166 Messina, Italy; Univ Glasgow, Glasgow G12 8QQ, Scotland; Univ York, York YO10 5DD, England; Univ Virginia, Charlottesville, VA 22901 USA; Coll William & Mary, Williamsburg, VA 23187 USA; Yerevan Phys Inst, Yerevan 375036, Armenia; Tech Univ Darmstadt, Fachbereich Phys, Darmstadt, Germany; Idaho State Univ, Pocatello, ID 83209 USA | Sabatie, Franck/K-9066-2015; McKinnon, Bryan/J-2928-2018; Isupov, Evgeny/J-2976-2012; Jo, Hyon-Suk/HGC-7070-2022; Zhao, Zhi-Wen/HZI-5398-2023; Khanal, Aaditya/ABI-5610-2020; POUDEL, JIWAN/KQU-6557-2024; Sparveris, Nikolaos/C-4751-2008; D'Angelo, Annalisa/A-2439-2012; Pokhrel, Madhusudhan/LGY-9951-2024; Schumacher, Reinhard/K-6455-2013; Tyson, Richard/LRC-4125-2024; Burkert, Volker/AAF-7395-2020; Deur, Alexandre/H-9778-2019; Joosten, Sylvester/HZL-4182-2023; Mascagna, Valerio/HLQ-1103-2023; Ireland, David/E-8618-2010; Bozzi, Giuseppe/H-7283-2017; Lanza, Lucilla/E-6479-2017; Pappalardo, Luciano/AAB-2380-2021; Zhang, Jixie/A-1461-2016; Lovato, Alessandro/AAB-7634-2022; Marsicano, Luca/KPB-4594-2024; MacGregor, Ian/D-4072-2011; Rossi, Patrizia/B-5943-2019; Hakobyan, Hayk/JUF-6461-2023; Filippi, Alessandra/JHU-4272-2023; Costantini, Giulio/F-3829-2018; Hyde, Charles/W-9190-2018; Holtrop, Maurik/A-9017-2010; Osipenko, Mikhail/N-8292-2015; Alaoui, Ahmed/B-4638-2015; Rocco, Noemi/K-9246-2017 | 24437436600; 57208800708; 57274817200; 57212416423; 44961438200; 56031197400; 57202533019; 35377851100; 6602115900; 36993853800; 35277104000; 57193121212; 57210826461; 35226938500; 23033257000; 7004520678; 35277104100; 57218527298; 7102358422; 57226649056; 35227021700; 35725064700; 35277071300; 56550149800; 57218357843; 7004440244; 7005853901; 57214364802; 57221142048; 57202987431; 57189889203; 6603765308; 36022213600; 35227101500; 7003468594; 57221147612; 55828029600; 6507987909; 59345445900; 56272524200; 6604025441; 57217562965; 35374416600; 57203386328; 35069234100; 35227171500; 57193421717; 26535686800; 14041647600; 35227171600; 9845148400; 56978985100; 57216999696; 8695796100; 35227304900; 57215024895; 6603686320; 35227280900; 57210932456; 7102183142; 57217000308; 7003432409; 25948329000; 34570410000; 57208726428; 56115055200; 57206656408; 7003821864; 22966851900; 57214681432; 7005060869; 57204617911; 35227424100; 57209456981; 35227460400; 35227429400; 57202638465; 23034837300; 57216594895; 57208691543; 13405022500; 36604596000; 35227558900; 57205462419; 6701392158; 56047689500; 6507646370; 56273696800; 9278396500; 7006040977; 7004889588; 57193833269; 22135531000; 35227669300; 57224626542; 35227656900; 7004546205; 12244632700; 6603294089; 57212715831; 35227746500; 35227763200; 57197510744; 6701825145; 6603112367; 57226647977; 22986163400; 7004207376; 36085149700; 35227791700; 8903140900; 57814422500; 57200602864; 55329126900; 35227871000; 7004527121; 57219768156; 7003515879; 6701495633; 56589489300; 7102538331; 58092074700; 57214597279; 35227896300; 7201653195; 57203683484; 35227996900; 15030349100; 57213706614; 55787422600; 6507906118; 7004491103; 22969481600; 7004321986; 57222078258; 35228099400; 22136651400; 6504161736; 36934412800; 6603350317; 57221067333; 13204321200; 57222271505; 57201559118; 57204955185; 36836386600; 57215210642; 57216598335 | hen@mit.edu; | PHYSICAL REVIEW C | PHYS REV C | 2469-9985 | 2469-9993 | 107 | 6 | SCIE | PHYSICS, NUCLEAR | 2023 | 3.2 | 29.5 | 0.72 | 2025-06-25 | 5 | 6 | SHORT-RANGE CORRELATIONS; ENERGY; DEPENDENCE | English | 2023 | 2023-06-06 | 10.1103/physrevc.107.l061301 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Safety and Effectiveness of SB2 (Infliximab Biosimilar) in Adult Patients with Immune-Mediated Inflammatory Diseases: A Post-Marketing Surveillance in Korea | Introduction: SB2 is a biosimilar of infliximab (IFX), which is approved for rheumatoid arthritis (RA), ankylosing spondylitis (AS), adult and pediatric Crohn's disease (CD), adult and pediatric ulcerative colitis (UC), psoriatic arthritis (PsA), and plaque psoriasis (PsO). The drug approval process in Korea includes post marketing surveillance (PMS) studies to re-examine the safety and effectiveness of approved new medications.Methods: This was a prospective, multi-center, open-label, observational, phase 4 PMS study of IFX-naive patients or patients switched from reference IFX or another IFX-biosimilar to SB2 in all approved indications. The primary end point was to evaluate the safety of SB2 reported as adverse events (AEs) and adverse drug reactions (ADRs). The secondary endpoint was to evaluate the effectiveness measured as investigators' overall effectiveness assessment, categorized as improved, stable, or worsened. Furthermore, disease-specific activity scores were collected for each indication [28-joint Modified Disease Activity Score (DAS28) for RA, Korean Bath Ankylosing Spondylitis Disease Activity Index (KBASDAI), Crohn's Disease Activity Index (CDAI), and Full Mayo Score for UC].Results: In the safety and effectiveness analysis, 180 and 128 patients were included, respectively. Most patients (83.9%) were IFX-naive patients and 16.1% were switched patients. RA (48.9%) and AS (31.1%) were the most frequent indications. Overall, 23 (12.8%) patients reported AEs and 14 (7.8%) patients reported ADRs. Serious adverse events (SAEs) were reported by 3 (1.7%) patients. As per investigators' overall effectiveness assessments, SB2 was effective in 94.6% (105/111) of IFX-naive patients and 82.4% (14/17) of switched patients. In IFX-naive patients, disease activity scores decreased significantly from baseline to week 30 (week 24 for AS); mean (SD) changes of disease scores for each indication were DAS28 -1.9 (0.79) for RA, KBASDAI -3.8 (1.68) for AS, CDAI -200.4 (112.47) for CD, and Full Mayo Score -6.6 (2.92) for UC. The persistence rate of SB2 treatments was 88.3% with median treatment duration of 30.1 weeks.Conclusion: This PMS study of the IFX-biosimilar SB2 in Korea confirmed the safety and effectiveness of SB2 in major indications. | Kim, Dong W.; Lee, Yousun; Kim, Geuntae; Kim, Sang H.; Cho, Dae H.; Choi, Jeongmin; Kwon, Yong H.; Park, Younjin; Choi, Wooree; Park, Dong I. | Inje Univ, Busan Paik Hosp, Dept Internal Med, Div Rheumatol, Busan, South Korea; Sungkyunkwan Univ, Samsung Changwon Hosp, Dept Internal Med, Div Rheumatol,Sch Med, Chang Won, South Korea; Kosin Univ, Gospel Hosp, Dept Internal Med, Div Rheumatol,Coll Med, Busan, South Korea; Keimyung Univ, Sch Med, Dept Internal Med, Div Rheumatol,Dongsan Hosp, Daegu, South Korea; Sungkyunkwan Univ, Samsung Changwon Hosp, Dept Internal Med, Div Gastroenterol & Hepatol,Sch Med, Chang Won, South Korea; Inje Univ, Dept Internal Med, Sanggye Paik Hosp, Seoul, South Korea; Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu, South Korea; Samsung Bioepis Co Ltd, Incheon, South Korea; Sungkyunkwan Univ, Kangbuk Samsung Hosp, Dept Internal Med, Div Gastroenterol,Sch Med, Seoul, South Korea | Kim, Dong/I-7600-2015 | 57201849481; 23028452200; 56013410100; 36470282200; 8307062000; 55646404000; 55775556800; 58046559700; 58046889500; 56524839700 | diksmc.park@samsung.com; | ADVANCES IN THERAPY | ADV THER | 0741-238X | 1865-8652 | 40 | 3 | SCIE | MEDICINE, RESEARCH & EXPERIMENTAL;PHARMACOLOGY & PHARMACY | 2023 | 3.4 | 29.5 | 0.28 | 2025-06-25 | 2 | 1 | Remaloce; SB2; Biosimilar; TNF inhibitor; Real world evidence; Rheumatoid arthritis; Ankylosing spondylitis; Crohn's disease; Ulcerative colitis; Psoriatic arthritis | CROHNS-DISEASE; EFFICACY; REMICADE(R); REGISTRY; THERAPY; COHORT; CT-P13 | Ankylosing spondylitis; Biosimilar; Crohn’s disease; Psoriatic arthritis; Real world evidence; Remaloce; Rheumatoid arthritis; SB2; TNF inhibitor; Ulcerative colitis | Adult; Arthritis, Psoriatic; Arthritis, Rheumatoid; Biosimilar Pharmaceuticals; Child; Humans; Infliximab; Product Surveillance, Postmarketing; Prospective Studies; Republic of Korea; Spondylitis, Ankylosing; Treatment Outcome; biological product; biosimilar agent; immunosuppressive agent; infliximab; rheumatoid factor; sb 2; tumor necrosis factor inhibitor; unclassified drug; biosimilar agent; infliximab; adult; ankylosing spondylitis; anus fissure; Article; Bath ankylosing spondylitis disease activity index; biliary cirrhosis; biological therapy; clinical practice; colitis; controlled study; Crohn disease; Crohn Disease Activity Index; DAS28; decreased appetite; disease activity score; disease duration; drug efficacy; drug hypersensitivity; drug indication; drug safety; drug withdrawal; duodenum ulcer; encephalitis; female; follow up; Full Mayo Score; headache; human; immunosuppressive treatment; infusion related reaction; Korean Bath Ankylosing Spondylitis Disease Activity Index; major clinical study; male; middle aged; monoclonal antibody therapy; multicenter study; observational study; open study; pain; paresthesia; phase 4 clinical trial; polyarthritis; postmarketing surveillance; productive cough; prospective study; pruritus; Psoriasis Area and Severity Index; psoriatic arthritis; rash; rheumatoid arthritis; South Korea; tinnitus; treatment duration; treatment outcome; treatment switching; ulcerative colitis; urticaria; vomiting; child; clinical trial; postmarketing surveillance | English | 2023 | 2023-03 | 10.1007/s12325-022-02404-x | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | A comparative investigation on theoretical models for forming limit diagram prediction of automotive sheet metals | Determination of sheet metal formability, which is commonly evaluated through a forming limit curve (FLC), is an essential task for part designs in the automotive engineering community. This study provides a coherent comparison among four theoretical FLC criteria including Swift's instability, Hill's localized neck, Storen-Rice bifurcation analysis, and Hora's MMFC. Within these criteria, closed-form solutions for FLC are available for fast and expensiveness explicitly estimating the forming limit diagram (FLD) of sheet metals. According to their closed-form solutions, an empirical suggestion is proposed to improve the accuracy of the theoretical FLC. Quantitative comparisons are then made to evaluate the performance of these criteria for numerous aluminum alloys and steel sheets which are frequently used in automotive industries. Based on the comparisons, the advantages and limitations of each model are discussed from a physical point of view, which appears to be a useful suggestion for selecting a proper theoretical model to evaluate the FLD of sheet metals without conducting experimental tests. | Quoc Tuan Pham; Thi Bich Mac; Young-Suk Kim; Duc Toan Nguyen | Ton Duc Thang Univ, Inst Compuat Sci, Div Computat Math & Engn, Ho Chi Minh City, Vietnam; Ton Duc Thang Univ, Fac Civil Engn, Ho Chi Minh City, Vietnam; Hungyen Univ Technol & Educ, Fac Mech Engn, Hungyen, Vietnam; Kyungpook Natl Univ, Sch Mech Engn, Daegu, South Korea; Hanoi Univ Sci & Technol, Sch Mech Engn, Hanoi, Vietnam | Mac, Thoa/F-2467-2018; Kim, Sang-Hoon/AAA-2248-2020; Nguyen, Duc-Toan/B-1029-2016; Pham, Quoc Tuan/AAH-8010-2019; Pham, Tuan/AAH-8010-2019 | 57191753992; 57213096815; 36065820800; 36805657000 | phamquoctuan@tdtu.edu.vn;toan.nguyenduc@hust.edu.vn; | MECHANICS BASED DESIGN OF STRUCTURES AND MACHINES | MECH BASED DES STRUC | 1539-7734 | 1539-7742 | 51 | 7 | SCIE | MECHANICS | 2023 | 2.9 | 29.7 | 0.84 | 2025-06-25 | 10 | 5 | Sheet metals; forming limit diagram; Swift's instability; Hill's localization; bifurcation analysis; modified maximum force criterion | STRAIN PATH; ALUMINUM; CURVE; FORMABILITY; ANISOTROPY; CRITERION; NECKING | bifurcation analysis; forming limit diagram; Hill’s localization; modified maximum force criterion; Sheet metals; Swift’s instability | Aluminum alloys; Bifurcation (mathematics); Formability; Metals; Sheet metal; Bifurcation analysis; Closed form solutions; Forming limit curve; Forming limit diagrams; Hill’s localization; Localisation; Maximum forces; Modified maximum force criteria; Swift’s instability; Theoretical modeling; Automotive industry | English | 2023 | 2023-07-03 | 10.1080/15397734.2021.1945461 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | A new PID controller design using differential operator for the integrating process | In the present study, a new control structure is proposed to control the integrating process. The proposed control structure is composed of both inner and outer controllers. The internal controller is integrated with the differ-ential operator to overcome the structural limitations of the PID controller to control the integrating process. The proposed internal feedback loop converts the integrating process into an open-loop stable process with a leaded phase. Moreover, it converts the process with higher ultimate frequency allowing the outer controller to be more strongly tuned. From the result of the simulation study, the proposed control structure guarantees better control performance than previous control methods. Furthermore, the control performance of the proposed method shows similar or better results than the previously proposed control methods (ITAE improved by 40.6% from the previous method in the water level control example). | Lim, Sanghun; Yook, Youngjin; Heo, Jea Pil; Im, Chang Gyu; Ryu, Kyung Hwan; Sung, Su Whan | Kyungpook Natl Univ, Dept Chem Engn, Daegu 41566, South Korea; Sunchon Natl Univ, Dept Chem Engn, 225 Jungang Ro, Sunchon 57922, South Korea | 57218849821; 58026365700; 57189221315; 57751994400; 55376077100; 7202731867 | khryu@scnu.ac.kr;suwhansung@knu.ac.kr; | COMPUTERS & CHEMICAL ENGINEERING | COMPUT CHEM ENG | 0098-1354 | 1873-4375 | 170 | SCIE | COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS;ENGINEERING, CHEMICAL | 2023 | 3.9 | 29.7 | 1.46 | 2025-06-25 | 9 | 13 | Integrating process; Internal feedback loop; Differential operator; PID controller | ONLINE PROCESS IDENTIFICATION; I-PD CONTROLLER; RULES; GAIN | Differential operator; Integrating process; Internal feedback loop; PID controller | Differential equations; Electric control equipment; Feedback; Mathematical operators; Process control; Proportional control systems; Stability criteria; Three term control systems; Water levels; Control methods; Control performance; Control structure; Differential operators; Integrating process; Internal feedback loop; Open-loop; PID controller design; PID controllers; Stable process; Controllers | English | 2023 | 2023-02 | 10.1016/j.compchemeng.2022.108105 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | On the Structure Lie Operator of a Real Hypersurface in the Complex Quadric | The almost contact metric structure that we have on a real hypersurface M in the complex quadric Q(m) = SOm+2/SOmSO2 allows us to define, for any nonnull real number k, the k-th generalized Tanaka-Webster connection on M, del((K) ). Associated to this connection, we have Cho and torsion operators F-X((k)) and T-X((k)), respectively, for any vector field X tangent to M. From them and for any symmetric operator B on M, we can consider two tensor fields of type (1,2) on M that we denote by B-F((k)) and B-T((k)), respectively. We classify real hypersurfaces M in Q(m) for which any of those tensors identically vanishes, in the particular case of B being the structure Lie operator L-xi on M. | Perez, Juan De Dios; Perez-Lopez, David; Suh, Young Jin | Univ Granada, Dept Geometria & Topol, Granada 18071, Spain; Univ Granada, IMAG Inst Matemat, Granada 18071, Spain; Kyungpook Natl Univ, Coll Nat Sci, Dept Math, Daegu 41566, South Korea; Res Inst Real & Complex Manifolds, Daegu 41566, South Korea | de Dios Perez, Juan/B-7768-2015 | 57205268627; 57219258293; 57205268556 | jdperez@ugr.es;davidpl109@correo.ugr.es;yjsuh@knu.ac.kr; | MATHEMATICA SLOVACA | MATH SLOVACA | 0139-9918 | 1337-2211 | 73 | 6 | SCIE | MATHEMATICS | 2023 | 0.9 | 29.7 | 0.4 | 2025-06-25 | 0 | 1 | Complex quadric; real hypersurface; structure Lie operator; kth generalized Tanaka-Webster connection; Lie derivative | 53B25; Primary 53C15 | English | 2023 | 2023-12-01 | 10.1515/ms-2023-0113 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Pulse response method for the Wiener-type nonlinear process identification | The Wiener-type nonlinear process where a nonlinear static block follows a linear dynamic subsystem is widely used to describe the dynamics of chemical processes. The present study proposes a new Wiener-type process identification method based on a narrow pulse response to cope with the relatively long process excitation requirement in the previous methods. The proposed identification method is developed based on the property of the Wiener-type nonlinear process that outputs of a linear dynamic subsystem is the same at two points when process outputs are equivalent at those points. The proposed method requires a relatively short process excitation (a single pulse response) but almost exactly estimates the Wiener-type nonlinear process. The simulation and experimental studies show the outstanding performance of the proposed method. | Lim, Sanghun; Heo, Jea Pil; Ryu, Kyung Hwan; Sung, Su Whan; Lee, Jietae; Lee, Friedrich Y. | Kyungpook Natl Univ, Dept Chem Engn, Daegu 41566, South Korea; Sunchon Natl Univ, Dept Chem Engn, 225 Jungang Ro, Sunchon 57922, South Korea; LX Hausys Amer, Atlanta, GA USA | Lee, Si/ABH-1408-2020 | 57218849821; 57189221315; 55376077100; 7202731867; 7601455194; 57211367408 | khryu@scnu.ac.kr;suwhansung@knu.ac.kr; | COMPUTERS & CHEMICAL ENGINEERING | COMPUT CHEM ENG | 0098-1354 | 1873-4375 | 172 | SCIE | COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS;ENGINEERING, CHEMICAL | 2023 | 3.9 | 29.7 | 0.22 | 2025-06-25 | 2 | 2 | Wiener-type nonlinear process; Process identification; Single pulse response; pH process | PREDICTIVE CONTROL; SERIES; MODEL | pH process; Process identification; Single pulse response; Wiener-type nonlinear process | Identification method; Linear dynamic subsystems; Nonlinear process identification; pH process; Process identification; Pulse response; Pulse response method; Single pulse; Single pulse response; Wiener-type nonlinear process; Random processes | English | 2023 | 2023-04 | 10.1016/j.compchemeng.2023.108178 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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