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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Article | Recommendations for the Use of Next-Generation Sequencing and the Molecular Tumor Board for Patients with Advanced Cancer: A Report from KSMO and KCSG Precision Medicine Networking Group | Next-generation sequencing (NGS) is becoming essential in the fields of precision oncology. With implementation of NGS in daily clinic, the needs for continued education, facilitated interpretation of NGS results and optimal treatment delivery based on NGS results have been addressed. Molecular tumor board (MTB) is multidisciplinary approach to keep pace with the growing knowledge of complex molecular alterations in patients with advanced solid cancer. Although guidelines for NGS use and MTB have been developed in western countries, there is limitation for reflection of Korea's public health environment and daily clinical practice. These recommendations provide a critical guidance from NGS panel testing to final treatment decision based on MTB discussion. | Yoon, Shinkyo; Kim, Miso; Hong, Yong Sang; Kim, Han Sang; Kim, Seung Tae; Kim, Jihun; Yun, Hongseok; Yoo, Changhoon; Ahn, Hee Kyung; Kim, Hyo Song; Lee, In Hee; Kim, In-Ho; Park, Inkeun; Jeong, Jae Ho; Cheon, Jaekyung; Kim, Jin Won; Yun, Jina; Lim, Sun Min; Cha, Yongjun; Jang, Se Jin; Zang, Dae Young; Kim, Tae Won; Kang, Jin Hyoung; Kim, Jee Hyun | Univ Ulsan, Asan Med Ctr, Coll Med, Dept Oncol, Seoul, South Korea; Seoul Natl Univ, Seoul Natl Univ Hosp, Coll Med, Dept Internal Med, Seoul, South Korea; Yonsei Univ, Yonsei Canc Ctr, Coll Med, Div Med Oncol, Seoul, South Korea; Sungkyunkwan Univ, Samsung Med Ctr, Sch Med, Div Hematol Oncol,Dept Med, Seoul, South Korea; Univ Ulsan, Asan Med Ctr, Coll Med, Dept Pathol, Seoul, South Korea; Seoul Natl Univ, Seoul Natl Univ Hosp, Coll Med, Dept Genom Med, Seoul, South Korea; Gachon Univ, Gil Med Ctr, Dept Internal Med, Div Med Oncol, Incheon, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Dept Oncol Hematol, Daegu, South Korea; Catholic Univ Korea, Seoul St Marys Hosp, Coll Med, Div Med Oncol,Dept Internal Med, Seoul, South Korea; CHA Univ, CHA Bundang Med Ctr, Sch Med, Dept Med Oncol, Seongnam, South Korea; Seoul Natl Univ, Bundang Hosp, Coll Med, Div Hematol Med Oncol,Dept Internal Med, Seongnam, South Korea; Soonchunhyang Univ, Bucheon Hosp, Dept Internal Med, Div Med Oncol, Bucheon, South Korea; Res Inst & Hosp, Ctr Colorectal Canc, Natl Canc Ctr, Goyang, South Korea; Hallym Univ, Med Ctr, Dept Internal Med, Anyang, South Korea | ; Yun, Hongseok/HOC-1240-2023; Kim, Jin Il/JWP-3629-2024; Kim, Han Sang/R-3768-2019; Kang, Jin Hyoung/KYQ-2256-2024; Lee, Kee-Joon/AAA-4090-2022; Kim, Tae Won/GRX-7323-2022; KIM, SEONG/E-4164-2012 | 27068097600; 55193756000; 16041816900; 57210812990; 8638723100; 57222101434; 56803204100; 22954694200; 50261094700; 8709524100; 57191881516; 55477690000; 25947690900; 57022763500; 57203287161; 55801992400; 35605178100; 56446114500; 57203061340; 56683699900; 57216641597; 56504151300; 56656852000; 56004266300 | jhkimmd@snu.ac.kr; | CANCER RESEARCH AND TREATMENT | CANCER RES TREAT | 1598-2998 | 2005-9256 | 54 | 1 | SCIE | ONCOLOGY | 2022 | 4.6 | 36.7 | 1.13 | 2025-06-25 | 14 | 12 | Key words Next -generation sequencing; Molecular tumor board; Advanced solid cancer; Precision medicine; Genomic alterations | DEAMINATION; DIAGNOSIS; PANELS | Advanced solid cancer; Genomic alterations; Molecular tumor board; Next-generation sequencing; Precision medicine | High-Throughput Nucleotide Sequencing; Humans; Medical Oncology; Neoplasms; Practice Guidelines as Topic; Precision Medicine; Republic of Korea; Societies, Medical; advanced cancer; Article; clinical decision making; high throughput sequencing; human; interdisciplinary research; Korea; medical society; personalized medicine; practice guideline; solid malignant neoplasm; genetics; high throughput sequencing; neoplasm; oncology; personalized medicine; procedures; South Korea | English | 2022 | 2022-01 | 10.4143/crt.2021.1115 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Exploring consumers' attitude formation toward their own brands when in crisis: cross-national comparisons between USA and China | Purpose This study aims to examine how culture influences consumer attitudes toward the brands of products they own during a product-harm crisis. To this end, average consumers from two countries - the USA, representing a highly individualistic society and China, a less individualistic (i.e. collectivist) society - are compared. Design/methodology/approach The study conducts an invariance test of the measurement model for a more rigorous comparison of the two countries. Structural equation modeling is performed to identify how average consumers respond to a product-harm crisis (e.g. iPhone explosion) based on survey results of 188 American and 197 Chinese consumers. Findings These results reveal that in both countries, an individual's susceptibility to a normative interpersonal influence determines their brand consciousness, which, in turn, enhances consumer attachment to well-known brands, resulting in favorable brand attitudes. During a brand crisis, an owned brand's buffering effect is observed among consumers high in brand consciousness in collectivistic but not in individualistic societies. The moderating role of feelings of betrayal on the brand attachment-consumer attitude relationship is also reported. Originality/value Culture shapes consumer behavioral patterns. In today's global market, a company's decisions are no longer limited by borders and many companies experience product failures. Thus, findings that show consumers' distinguishable psychological experiences between different cultures contribute to crisis management literature. | Kim, Sojung; Yim, Mark Yi-Cheon | Kyungpook Natl Univ, Dept Journalism & Mass Commun, Daegu, South Korea; Univ Massachusetts Lowell, Robert J Manning Sch Business, Dept Mkt Entrepreneurship & Innovat, Lowell, MA USA | 37057544300; 55914652400 | sojungkim@knu.ac.kr;mark_yim@uml.edu; | JOURNAL OF PRODUCT AND BRAND MANAGEMENT | J PROD BRAND MANAG | 1061-0421 | 2054-1643 | 31 | 1 | SSCI | BUSINESS;MANAGEMENT | 2022 | 5.6 | 36.8 | 1.46 | 2025-06-25 | 22 | 22 | Brand consciousness; Crisis management; Brand attitude; Cross-cultural research; Brand attachment; Product-harm crisis; Feeling of betrayal; SNII | PSYCHOLOGICAL CONTRACT VIOLATION; PRODUCT-HARM CRISES; MEASUREMENT INVARIANCE; NEGATIVE PUBLICITY; MODERATING ROLE; METHOD BIAS; BETRAYAL; ATTRIBUTIONS; ATTACHMENT; RESPONSES | Brand attachment; Brand attitude; Brand consciousness; Crisis management; Cross-cultural research; Feeling of betrayal; Product-harm crisis; SNII | English | 2022 | 2022-01-06 | 10.1108/jpbm-01-2020-2731 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Structure- and Interaction-Based Design of Anti-SARS-CoV-2 Aptamers | Aptamer selection against novel infections is a complicated and time-consuming approach. Synergy can be achieved by using computational methods together with experimental procedures. This study aims to develop a reliable methodology for a rational aptamer in silico et vitro design. The new approach combines multiple steps: (1) Molecular design, based on screening in a DNA aptamer library and directed mutagenesis to fit the protein tertiary structure; (2) 3D molecular modeling of the target; (3) Molecular docking of an aptamer with the protein; (4) Molecular dynamics (MD) simulations of the complexes; (5) Quantum-mechanical (QM) evaluation of the interactions between aptamer and target with further analysis; (6) Experimental verification at each cycle for structure and binding affinity by using small-angle X-ray scattering, cytometry, and fluorescence polarization. By using a new iterative design procedure, structure- and interaction-based drug design (SIBDD), a highly specific aptamer to the receptor-binding domain of the SARS-CoV-2 spike protein, was developed and validated. The SIBDD approach enhances speed of the high-affinity aptamers development from scratch, using a target protein structure. The method could be used to improve existing aptamers for stronger binding. This approach brings to an advanced level the development of novel affinity probes, functional nucleic acids. It offers a blueprint for the straightforward design of targeting molecules for new pathogen agents and emerging variants. | Mironov, Vladimir; Shchugoreva, Irina A.; Artyushenko, Polina, V; Morozov, Dmitry; Borbone, Nicola; Oliviero, Giorgia; Zamay, Tatiana N.; Moryachkov, Roman, V; Kolovskaya, Olga S.; Lukyanenko, Kirill A.; Song, Yanling; Merkuleva, Iuliia A.; Zabluda, Vladimir N.; Peters, Georgy; Koroleva, Lyudmila S.; Veprintsev, Dmitry V.; Glazyrin, Yury E.; Volosnikova, Ekaterina A.; Belenkaya, Svetlana, V; Esina, Tatiana, I; Isaeva, Anastasiya A.; Nesmeyanova, Valentina S.; Shanshin, Daniil, V; Berlina, Anna N.; Komova, Nadezhda S.; Svetlichnyi, Valery A.; Silnikov, Vladimir N.; Shcherbakov, Dmitriy N.; Zamay, Galina S.; Zamay, Sergey S.; Smolyarova, Tatyana; Tikhonova, Elena P.; Chen, Kelvin H-C; Jeng, U-Ser; Condorelli, Gerolama; Franciscis, Vittorio; Groenhof, Gerrit; Yang, Chaoyong; Moskovsky, Alexander A.; Fedorov, Dmitri G.; Tomilin, Felix N.; Tan, Weihong; Alexeev, Yuri; Berezovski, Maxim, V; Kichkailo, Anna S. | Lomonosov Moscow State Univ, Dept Chem, Moscow 119991, Russia; Kyungpook Natl Univ, Dept Chem, Daegu 702701, South Korea; Fed Res Ctr KSC SB RAS, Lab Digital Controlled Drugs & Theranost, Krasnoyarsk 660036, Russia; Natl Tsing Hua Univ, Dept Chem Engn, Hsinchu 30013, Taiwan; Siberian Fed Univ, Sch Nonferrous Met & Mat Sci, Krasnoyarsk 660041, Russia; IRCCS Neuromed Ist Neurol Mediterraneo Pozzilli, Via Atinense 18, I-86077 Pozzilli, Italy; Krasnoyarsk State Med Univ, Lab Biomol & Med Technol, Krasnoyarsk 660022, Russia; Univ Jyvaskyla, Nanosci Ctr, Jyvaskyla 40014, Finland; Univ Jyvaskyla, Dept Chem, Jyvaskyla 40014, Finland; Univ Naples Federico II, Dept Pharm, I-80138 Naples, Italy; Univ Naples Federico II, Dept Mol Med & Med Biotechnol, I-80131 Naples, Italy; Kirensky Inst Phys, Lab Phys Magnet Phenomena, Krasnoyarsk 660012, Russia; Siberian Fed Univ, Sch Fundamental Biol & Biotechnol, Krasnoyarsk 660041, Russia; Xiamen Univ, Coll Chem & Chem Engn, Dept Chem Biol, Xiamen 361005, Peoples R China; State Res Ctr Virol & Biotechnol Vector, Koltsov 630559, Russia; NRC Kurchatov Inst, Moscow 117259, Russia; Russian Acad Sci, Siberian Branch, Inst Chem Biol & Fundamental Med, Novosibirsk 630090, Russia; Russian Acad Sci, Res Ctr Biotechnol, AN Bach Inst Biochem, Lab Immunobiochem, Moscow 119071, Russia; Tomsk State Univ, Lab Adv Mat & Technol, Tomsk 634050, Russia; Altai State Univ, Barnaul 656049, Russia; Fed Res Ctr KSC SB RAS, Dept Mol Elect, Krasnoyarsk 660036, Russia; Krasnoyarsk State Med Univ, Dept Infect Dis & Epidemiol, Krasnoyarsk 660022, Russia; Natl Pingtung Univ, Dept Appl Chem, Pingtung 900391, Taiwan; Natl Synchrotron Radiat Res Ctr, Hsinchu Sci Pk, Hsinchu 30076, Taiwan; Res Natl Council CNR, Inst Genet & Biomed Res IRGB, I-09042 Milan, Italy; Shanghai Jiao Tong Univ, Sch Med, Renji Hosp, Inst Mol Med, Shanghai 200127, Peoples R China; Natl Inst Adv Ind Sci & Technol, Res Ctr Computat Design Adv Funct Mat, Tsukuba, Ibaraki 3058560, Japan; Hunan Univ, Coll Chem & Chem Engn, Changsha 410082, Hunan, Peoples R China; Argonne Natl Lab, Computat Sci Div, Lemont, IL 60439 USA; Dept Chem & Biomol Sci, Ottawa, ON K1N 6N5, Canada | Berezovski, Maxim/MZQ-3758-2025; Oliviero, Giorgia/M-9020-2014; Isaeva, Anastasya/ABD-2413-2021; Song, Yanling/AAT-7783-2020; Shcherbakov, Dmitry/U-4763-2019; Alexeev, Yuri/AAW-5130-2020; Yang, Chaoyong/F-9741-2010; Tomilin, Felix/F-3763-2014; Artyushenko, Polina/AAO-8226-2020; Kolovskaya, Olga/E-8066-2014; Belenkaya, Svetlana/AAG-8869-2020; Mironov, Vladimir/I-4712-2012; Koroleva, Lyudmila/H-1116-2013; Peters, Georgy/O-9797-2015; Svetlichnyi, Valery/O-1286-2013; Moskovsky, Alexander/AAO-7602-2020; Berlina, Anna/F-8900-2017; Lukyanenko, Kirill/K-7124-2017; yang, chaoyong/F-9741-2010; Esina, Tatiana/C-7572-2014; Komova, Nadezhda/AAE-3245-2019; Zamay, Galina/E-8076-2014; Zamay, Tatiana/D-8443-2014; Glazyrin, Yury/P-1135-2014; Morozov, Dmitry/Q-2433-2017; Tan, Weihong/AAA-4536-2020; Vladimir, Silnikov/ABB-2183-2021; Smolyarova, Tatyana/AAS-6145-2021; Kich, Annо/H-2079-2012; Moryachkov, Roman/L-8949-2015; Шаньшин, Даниил/AAO-5973-2020; Borbone, Nicola/A-6061-2009; Merkuleva, Iuliia/AAV-2012-2021; Nesmeyanova, Valentina/AAG-8304-2020; Kichkailo, Anna/H-2079-2012 | 16203310700; 57206772345; 26429141000; 26536517500; 6507575589; 6701466694; 8504768500; 57210322419; 37461620200; 57191378723; 55372399700; 57232714000; 6602148689; 57189001357; 15846216700; 57191412312; 55613657900; 36626467100; 57205184299; 57190121468; 56878712900; 57254579000; 57201673986; 21742180800; 57209730245; 35514642000; 6701720769; 37027118800; 37462346700; 8858514300; 57195672292; 57203849763; 8146616100; 57154898100; 7005775848; 7003496087; 6506118299; 57204948551; 56245309300; 56842563500; 6602246772; 7401959760; 6602740577; 6508080466; 8504768600 | yuri@alcf.anl.gov;kichkailo.as@ksc.krasn.ru;maxim.berezovski@uottawa.ca; | CHEMISTRY-A EUROPEAN JOURNAL | CHEM-EUR J | 0947-6539 | 1521-3765 | 28 | 12 | SCIE | CHEMISTRY, MULTIDISCIPLINARY | 2022 | 4.3 | 36.8 | 1.54 | 2025-06-25 | 22 | 23 | aptamers; fragment molecular orbitals method; molecular dynamics; SARS-CoV-2; SAXS | BIOLOGICAL MACROMOLECULES; SOLUTION SCATTERING; BINDING; SPIKE; OPTIMIZATION; RESOLUTION; DISCOVERY; SELECTION; PIPELINE; DOCKING | aptamers; fragment molecular orbitals method; molecular dynamics; SARS-CoV-2; SAXS | Aptamers, Nucleotide; COVID-19; Humans; Molecular Docking Simulation; Molecular Dynamics Simulation; SARS-CoV-2; SELEX Aptamer Technique; Spike Glycoprotein, Coronavirus; 3D modeling; Binding energy; Diseases; Iterative methods; Molecular dynamics; Molecular modeling; Molecular orbitals; Nucleic acids; Proteins; Quantum theory; X ray scattering; aptamer; coronavirus spike glycoprotein; spike protein, SARS-CoV-2; Aptamers; Dna aptamer; Drug Design; Experimental procedure; Fragment molecular orbital methods; In-silico; Molecular design; New approaches; SARS-CoV-2; SAXS; chemistry; human; molecular docking; molecular dynamics; systematic evolution of ligands by exponential enrichment aptamer technique; SARS | English | 2022 | 2022-02-24 | 10.1002/chem.202104481 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | A monomeric iron(III) compound containing N-(2-pyridylmethyl) iminodiisopropanolate and thiocyanato ligands: structure, magnetic and catalytic properties | The reaction of Fe(NO3)(3)center dot 9H(2)O, sodium thiocyanate, and N-(2-pyridylmethyl)iminodiisopropanol (H(2)pmidip) in methanol/water mixture solution leads to the formation of a mononuclear iron(III) compound of [Fe-III(Hpmidip)(NCS)(2)] (1). The iron ion of 1 has a distorted octahedral structure that is bonded by two thiocyanate anions and one Hpmidip(-) ligand. One of the two hydroxyl moieties in H(2)pmidip is depmtonated, while the other is involved in hydrogen bonding interactions to form a dimeric structure. The magnetic properties of 1 reveal a very weak antiferromagnetic interaction within the dimer with parameters J = -0.75 cm(-1) and g = 2.068. 1 showed that the catalytic oxidations for a variety of olefins are selective and effective with moderate yields using meta-chloroperoxybenzoic acid (m-CPBA). For the identification of the mechanism for olefin epoxidation in 1, the O-O bond cleavage of peroxyphenylacetic acid (PPAA) and competitive experiments of cis- and trans-2-octene have been investigated. | Shin, Hye Jin; Lee, Sojeong; Kim, Cheal; Min, Kil Sik | Kyungpook Natl Univ, Dept Chem Educ, Daegu 41566, South Korea; Seoul Natl Univ Sci & Technol, Dept Fine Chem, Seoul 01811, South Korea | 57217093676; 57211133642; 7409879911; 7201466885 | chealkim@seoultech.ac.kr;minks@knu.ac.kr; | INORGANICA CHIMICA ACTA | INORG CHIM ACTA | 0020-1693 | 1873-3255 | 535 | SCIE | CHEMISTRY, INORGANIC & NUCLEAR | 2022 | 2.8 | 36.9 | 0.2 | 2025-06-25 | 2 | 2 | Tetradentate; Iron compound; Thiocyanate; Hydrogen bond; Magnetism; Catalysis | BOND-VALENCE PARAMETERS; SPIN-CROSSOVER; OLEFIN EPOXIDATION; IRON COMPLEXES; TETRADENTATE LIGANDS; CRYSTAL-STRUCTURE; SUM ANALYSIS; N2O2; OXIDATION; DINUCLEAR | Catalysis; Hydrogen bond; Iron compound; Magnetism; Tetradentate; Thiocyanate | Catalytic oxidation; Dimers; Hydrogen bonds; Ligands; Magnetism; Metal ions; Olefins; Catalytic properties; Iron ions; Ligand structure; Methanol/water mixtures; Mixture solution; Monomerics; Sodium thiocyanates; Structure property; Tetradentate; Thiocyanate; Iron compounds | English | 2022 | 2022-05-24 | 10.1016/j.ica.2022.120877 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | A multicenter, randomized, open-label, comparative, phase IV study to evaluate the efficacy and safety of combined treatment with mycophenolate mofetil and corticosteroids in advanced immunoglobulin A nephropathy | Background: It remains unclear whether immunosuppressive agents are effective in patients with immunoglobulin A nephropathy (IgAN). We investigated the efficacy of a mycophenolate mofetil (MMF) and corticosteroid combination therapy in patients with advanced IgAN. Methods: We conducted a multicenter, randomized, placebo-controlled, parallel-group study of 48 weeks administration of MMF and corticosteroids in biopsy-proven advanced IgAN patients with estimated glomerular filtration rate (eGFR) of 20-50 mL/min/1.73 m(2) and urine protein-to-creatinine ratio (UPCR) of >0.75 g/day. The primary outcome was complete (UPCR 50% reduction of UPCR compared to baseline) remission at 48 weeks. Results: Among the 48 randomized patients, the percentage that achieved complete or partial remission was greater in the combination therapy group than in the control group (4.2% vs. 0% and 29.1% vs. 5.0%, respectively). Compared with the combination therapy group, eGFR in the control group decreased significantly from week 36 onward, resulting in a final adjusted mean change of -4.39 +/- 1.22 mL/min/1.73 m(2) (p = 0.002). The adjusted mean changes after 48 weeks were 0.62 +/- 1.30 and -5.11 +/- 1.30 mL/min/1.73 m(2) (p = 0.005) in the treatment and control groups, respectively. The UPCR was significantly different between the two groups; the adjusted mean difference was -0.47 +/- 0.17 mg/mgCr and 0.07 +/- 0.17 mg/mgCr in the treatment and control group, respectively (p = 0.04). Overall adverse events did not differ between the groups. Conclusion: In advanced IgAN patients with a high risk for disease progression, combined MMF and corticosteroid therapy appears to be beneficial in reducing proteinuria and preserving renal function. | Han, Sang Youb; Jung, Chan-Young; Lee, Sang Ho; Lee, Dong Won; Lee, Sik; Kim, Chan-Duck; Choi, Bum Soon; Kim, Beom Seok | Inje Univ, Coll Med, Dept Internal Med, Goyang, South Korea; Yonsei Univ, Dept Internal Med, Coll Med, 50-1 Yonsei Ro, Seoul 03772, South Korea; Kyung Hee Univ, Dept Internal Med, Coll Med, Seoul, South Korea; Pusan Natl Univ, Dept Internal Med, Sch Med, Yangsan, South Korea; Chonbuk Natl Univ, Dept Internal Med, Med Sch, Jeonju, South Korea; Kyungpook Natl Univ Hosp, Dept Internal Med, Daegu, South Korea; Catholic Univ Korea, Coll Med, Dept Internal Med, 222 Banpo Daero, Seoul 06591, South Korea | Kim, Soo-Yeon/ADR-9663-2022; Jung, Chan/HTG-3801-2023 | 57216860543; 57221559510; 55890136000; 57199467944; 57192521521; 8558530700; 7402755304; 56127911000 | sooncb@catholic.ac.kr;docbsk@yuhs.ac; | KIDNEY RESEARCH AND CLINICAL PRACTICE | KIDNEY RES CLIN PRAC | 2211-9132 | 2211-9140 | 41 | 4 | SCIE | UROLOGY & NEPHROLOGY | 2022 | 3 | 36.9 | 1.25 | 2025-06-25 | 9 | 8 | Corticosteroids; IgA nephropathy; Immunosuppressants; Mycophenolate mofetil; Proteinuria | IGA NEPHROPATHY; NEPHROTIC SYNDROME; RISK; METHYLPREDNISOLONE; PLACEBO; TRIAL | Corticosteroids; IgA nephropathy; Immunosuppressants; Mycophenolate mofetil; Proteinuria | albumin; chloride; corticosteroid; creatinine; glucose; hemoglobin; immunosuppressive agent; mycophenolate mofetil; potassium; prednisolone; protein; sodium; abdominal discomfort; abdominal pain; adult; adverse event; Article; basophil count; biopsy; body weight; calibration; clinical article; clinical trial; comparative study; controlled study; creatinine blood level; dermatitis; diarrhea; diastolic blood pressure; disease exacerbation; drug efficacy; drug safety; dry eye; dysgeusia; dyspepsia; edema; eosinophil count; epigastric discomfort; esophagitis; estimated glomerular filtration rate; fatigue; follow up; gastritis; gastrointestinal disease; good clinical practice; heart rate; hematologic disease; human; human tissue; hypertension; immunoglobulin A nephropathy; infection; inflammation; isotope dilution assay; kidney function; leukocyte count; lymphocyte count; male; mass spectrometry; maximum tolerated dose; middle aged; monocyte count; multicenter study; nausea and vomiting; outcome assessment; overall response rate; phase 4 clinical trial; platelet count; practice guideline; protein creatinine ratio; proteinuria; randomized controlled trial; remission; renal replacement therapy; renin angiotensin aldosterone system; sinusitis; sudden death; systolic blood pressure; urea nitrogen blood level; urinalysis; urinary tract infection | English | 2022 | 2022-07 | 10.23876/j.krcp.21.146 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Review | A new pathological perspective on thrombotic microangiopathy | Thrombotic microangiopathy (TMA) refers to a condition caused by microvascular injury that includes thrombosis, hemolytic anemia, and thrombocytopenia. There are two classic TMAs, hemolytic uremic syndrome (HUS) and thrombotic thrombocytopenic purpura, as well as an atypical HUS (aHUS). aHUS includes a broad spectrum of disorders with diverse etiologies and shares clinical manifestations with classic TMA; however, it frequently lacks typical clinical and laboratory findings. These traits can confuse clinicians and pathologists in terms of renal pathologic diagnosis, especially in cases where TMA is associated with other glomerulopathies or hypertensive renal disease. In this review, new paradigms for classifying TMA and the diversity of histopathologic changes including associated renal diseases are discussed. Renal biopsy is an important and useful diagnostic tool for diagnosing TMA and identifying TMA changes in other renal diseases, including hypertension. Adopting the term "TMA features " for TMA-like changes in glomerulus or artery/ arteriole in addition to the pathological diagnosis of glomerulopathy would be informative to clinicians for a prompt diagnosis and treatment of aHUS. | Kim, Yong-Jin | Kyungpook Natl Univ Hosp, Dept Pathol, 130 Dongdeok Ro, Daegu 41944, South Korea | Kim, Yong-Jin/J-2745-2012 | 56150365500 | yyjjkim@knu.ac.kr; | KIDNEY RESEARCH AND CLINICAL PRACTICE | KIDNEY RES CLIN PRAC | 2211-9132 | 2211-9140 | 41 | 5 | SCIE | UROLOGY & NEPHROLOGY | 2022 | 3 | 36.9 | 1.02 | 2025-06-25 | 15 | 17 | Atypical hemolytic uremic syndrome; Classification; Complement C4d; Pathology; Thrombotic microangiopathies | HEMOLYTIC-UREMIC SYNDROME; COMPLEMENT INHIBITOR ECULIZUMAB; IMMUNOGLOBULIN-A NEPHROPATHY; INTRARENAL ARTERIAL LESIONS; IGA NEPHROPATHY; THROMBOCYTOPENIC PURPURA; OXFORD CLASSIFICATION; FACTOR-H; GLOMERULOPATHY; HYPERTENSION | Atypical hemolytic uremic syndrome; Classification; Complement C4d; Pathology; Thrombotic microangiopathies | complement component C4d; eculizumab; anemia; arteriole; artery wall; atypical hemolytic uraemic syndrome; complement activation; electron microscopy; endothelium cell; gene mutation; glomerulopathy; glomerulus; glomerulus basement membrane; hemolytic uremic syndrome; human; hyaline degeneration; hypertension; immunoglobulin A nephropathy; immunohistochemistry; kidney biopsy; kidney disease; kidney function; kidney graft; microangiopathy; microvasculature; plasma exchange; platelet count; proteinuria; pulmonary hypertension; renin angiotensin aldosterone system; Review; shear stress; systemic lupus erythematosus; thrombocytopenia; thrombosis; thrombotic microangiopathy; thrombotic thrombocytopenic purpura | English | 2022 | 2022-09 | 10.23876/j.krcp.22.010 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Clinical outcomes in pediatric patients with normal renal histopathology | Background: There have been some cases where abnormal histopathologic findings could not be found in the kidney could even with proper specimen collection through percutaneous renal biopsy (PRB) in accordance with its indication. We analyzed the incidence and clinical outcomes of children who showed normal histopathological findings in their PRBs. Methods: The medical records of 552 pediatric subjects who underwent PRB between 2005 and 2016 were reviewed. Twenty-six subjects were excluded because allograft biopsy was performed in nine subjects, and the age at biopsy was greater than 18 years in 17 subjects. Finally, 526 subjects were enrolled in this study. Results: Of the 526 pediatric patients, 32 (6.1%) showed no histopathological abnormalities in their PRBs. The male-to-female ratio of the patients was 1.9:1, and the mean ages at the first visit and at biopsy were 10.6 +/- 4.1 and 11.4 +/- 3.8 years, respectively. In accordance with the biopsy indications, recurrent gross hematuria showed the highest incidence rate, but combined hematuria and proteinuria had the lowest incidence rate regarding normal renal histopathology among all the subjects. At a mean follow-up of 35.5 +/- 23.6 months, urinary abnormalities had improved in more than 50% of the subjects with normal renal histopathology, and none of the patients showed progression to end-stage renal disease or required rebiopsy due to symptom worsening during the follow-up period. Conclusion: The clinical outcomes of children with normal PRB histopathologic findings are generally good. Further studies to evaluate their long-term outcomes are needed. | Kwak, Naeun; Park, Min Ji; Jang, Hea Min; Baek, Hee Sun; Lee, Sang In; Han, Man Hoon; Kim, Yong-Jin; Cho, Min Hyun | Kyungpook Natl Univ, Sch Med, Dept Pediat, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Pathol, Daegu, South Korea | Kim, Yong-Jin/J-2745-2012 | 57425087100; 57425372600; 57216601178; 56689379700; 57190228866; 57194067936; 56150365500; 7401727726 | chomh@knu.ac.kr; | KIDNEY RESEARCH AND CLINICAL PRACTICE | KIDNEY RES CLIN PRAC | 2211-9132 | 2211-9140 | 41 | 1 | SCIE | UROLOGY & NEPHROLOGY | 2022 | 3 | 36.9 | 0.31 | 2025-06-25 | 2 | 2 | Biopsy; Child; Hematuria; Proteinuria | NATURAL-HISTORY; BIOPSY; CHILDREN; HEMATURIA; KIDNEY; PROTEINURIA | Biopsy; Child; Hematuria; Proteinuria | hemoglobin; serum albumin; analytical parameters; Article; calcium blood level; calcium to creatinine ratio; child; creatinine blood level; Doppler ultrasonography; echography; electron microscopy; end stage renal disease; estimated glomerular filtration rate; female; hematuria; histopathology; human; human tissue; immunofluorescence; immunoglobulin A nephropathy; interstitial nephritis; kidney biopsy; kidney function test; major clinical study; male; microscopy; orthostatic proteinuria; pediatric patient; protein creatinine ratio; proteinuria; renal echography; school child; thin basement membrane nephropathy; urea nitrogen blood level; urinalysis | English | 2022 | 2022-01 | 10.23876/j.krcp.21.091 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | COVID-19-related clinical outcomes among Korean hemodialysis patients | Background: Hemodialysis (HD) patients are more vulnerable to viral epidemics, experiencing higher mortality rates compared to individuals without chronic kidney disease (CKD). This retrospective cohort study sought to demonstrate clinical outcomes and associated factors among coronavirus disease 2019 (COVID-19) confirmed Korean HD patients.Methods: From February 2020 to November 2021, the COVID-19 Task Force Team collected clinical data for HD patients with confirmed COVID-19 via a self-report survey of nephrologists. The composite outcome included in-hospital mortality, admission to the intensive care unit (ICU), and use of mechanical ventilation. Risk factors associated with clinical outcomes were analyzed among HD patients and compared to those of individuals without CKD using the COVID-19 database from the Korea Disease Control and PreResults: A total of 380 HD patients from 206 facilities were diagnosed with COVID-19. Fever (49.5%) and cough (25.7%) were the two most common initial symptoms. The overall in-hospital fatality rate was 22.4% and even higher among ICU admission cases (64.7%). Non-survivors were older, more frequently developed shortness of breath, and were more likely to come from a nursing hospital. Compared to the age- and sex-matched non-CKD population, HD patients showed greater risk of in-hospital mortality (hazard ratio, 2.07; 95% confidence interval, 1.56-2.75; p < 0.001) and composite outcome (hazard ratio, 3.50; 95% confidence interval,Conclusion: HD patients have a greater risk of in-hospital mortality and morbidity from COVID-19. Special attention should be paid to COVID-19 HD patients when they are older or present with symptoms. | Park, Hayne Cho; Lee, Young-Ki; Ko, Eunsil; Yu, Sungbong; Cho, AJin; Kim, Do Hyoung; Kim, Jinseog; Cho, Jang-Hee; Lee, Jeonghwan; Kim, Dong Ki; Kim, Seong Nam; Yang, Chul-Woo | Hallym Univ, Dept Internal Med, Kangnam Sacred Heart Hosp, 1 Singil Ro, Seoul 07441, South Korea; Hallym Univ, Hallym Kidney Res Inst, Coll Med, Seoul, South Korea; Natl Med Ctr, Natl Emergency Med Ctr, Seoul, South Korea; Good Samaritan Bagae Hosp, Dept Gen Surg, Pyeongtaek, South Korea; Dongguk Univ, Dept Bigdata & Appl Stat, Gyeongju, South Korea; Kyungpook Natl Univ Hosp, Dept Internal Med, Daegu, South Korea; Seoul Natl Univ, Dept Internal Med, Coll Med, Seoul, South Korea; Kim Seong Nam Internal Med Clin, Seoul, South Korea; Catholic Univ Korea, Coll Med, Dept Internal Med, Seoul, South Korea | ; Kim, Do Hyoung/AAE-7557-2022; Cho, Jang-hee/ABD-3534-2020; Kim, Dong Ki/J-5389-2012; Lee, Jeonghwan/C-5214-2011 | 34771965700; 55716130600; 57802018900; 57913745700; 56506366900; 57215136490; 8286494600; 7403536291; 57203144567; 23479259100; 37031276200; 7407743404 | km2071@hallym.or.kr; | KIDNEY RESEARCH AND CLINICAL PRACTICE | KIDNEY RES CLIN PRAC | 2211-9132 | 2211-9140 | 41 | 5 | SCIE | UROLOGY & NEPHROLOGY | 2022 | 3 | 36.9 | 1.88 | 2025-06-25 | 13 | 12 | COVID-19; Dialysis; Mortality; Risk factors | COVID-19; Dialysis; Mortality; Risk factors | adult; Article; chronic kidney failure; clinical outcome; controlled study; coronavirus disease 2019; dyspnea; female; fever; hemodialysis; hemodialysis patient; hospitalization; human; human experiment; in-hospital mortality; intensive care unit; male; middle aged; mortality; nephrologist; rhinorrhea; risk factor; sore throat | English | 2022 | 2022-09 | 10.23876/j.krcp.22.023 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Effect of shared decision-making education on physicians' perceptions and practices of end-of-life care in Korea | Background: Evidence of the ethical appropriateness and clinical benefits of shared decision-making (SDM) are accumulating. This study aimed to not only identify physicians' perspectives on SDM, and practices related to end-of-life care in particular, but also to gauge the effect of SDM education on physicians in Korea. Methods: A 14-item questionnaire survey using a modified Delphi process was delivered to nephrologists and internal medicine trainees at 17 university hospitals. Results: A total of 309 physicians completed the survey. Although respondents reported that 69.9% of their practical decisions were made using SDM, 59.9% reported that it is not being applied appropriately. Only 12.3% of respondents had received education on SDM as part of their training. The main obstacles to appropriate SDM were identified as lack of time (46.0%), educational materials and tools (29.4%), and education on SDM (24.3%). Although only a few respondents had received training on SDM, the proportion of those who thought they were using SDM appropriately in actual practice was high; the proportion of those who chose lack of time and education as factors that hindered the proper application of SDM was low. Conclusion: The majority of respondents believed that SDM was not being implemented properly in Korea, despite its use in actual practice. To improve the effectiveness of SDM in the Korean medical system, appropriate training programs and supplemental policies that guarantee sufficient application time are required. | Yu, Byung Chul; Han, Miyeun; Ko, Gang-Jee; Yang, Jae Won; Kwon, Soon Hyo; Chung, Sungjin; Hong, Yu Ah; Hyun, Young Youl; Cho, Jang-Hee; Yoo, Kyung Don; Bae, Eunjin; Park, Woo Yeong; Sun, In O.; Kim, Dongryul; Kim, Hyunsuk; Hwang, Won Min; Song, Sang Heon; Shin, Sung Joon | Soonchunhyang Univ, Dept Internal Med, Div Nephrol, Bucheon Hosp, Bucheon, South Korea; Hallym Univ, Coll Med, Dept Internal Med, Div Nephrol,Hangang Sacred Heart Hosp, Seoul, South Korea; Korea Univ, Coll Med, Dept Internal Med, Div Nephrol,Guro Hosp, Seoul, South Korea; Yonsei Univ, Dept Internal Med, Div Nephrol, Wonju Coll Med, Wonju, South Korea; Soonchunhyang Univ, Dept Internal Med, Div Nephrol, Seoul Hosp, Seoul, South Korea; Catholic Univ Korea, Coll Med, Dept Internal Med, Div Nephrol,Yeouido St Marys Hosp, Seoul, South Korea; Catholic Univ Korea, Coll Med, Dept Internal Med, Div Nephrol,Daejeon St Marys Hosp, Daejeon, South Korea; Sungkyunkwan Univ, Kangbuk Samsung Hosp, Dept Internal Med, Div Nephrol,Sch Med, Seoul, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Div Nephrol,Dept Internal Med, Daegu, South Korea; Univ Ulsan, Ulsan Univ Hosp, Dept Internal Med, Div Nephrol,Coll Med, Ulsan, South Korea; Gyeongsang Natl Univ, Dept Internal Med, Div Nephrol, Changwon Hosp, Chang Won, South Korea; Keimyung Univ, Dongsan Hosp, Dept Internal Med, Div Nephrol,Sch Med, Daegu, South Korea; Presbyterian Med Ctr, Dept Internal Med, Div Nephrol, Jeonju, South Korea; Catholic Univ Korea, Dept Internal Med, Div Nephrol, Incheon St Marys Hosp,Coll Med, Seoul, South Korea; Hallym Univ, Coll Med, Dept Internal Med, Div Nephrol,Chuncheon Sacred Heart Hosp, Chunchon, South Korea; Konyang Univ Hosp, Dept Internal Med, Div Nephrol, Daejeon, South Korea; Pusan Natl Univ, Pusan Natl Univ Hosp, Dept Internal Med, Div Nephrol,Sch Med, Busan, South Korea; Dongguk Univ, Ilsan Hosp, Dept Internal Med, Div Nephrol,Sch Med, Goyang, South Korea | Cho, Jang-hee/ABD-3534-2020; Hong, Yu/AAB-7055-2020; Han, Miyeun/AAE-7569-2022; Chung, Sungjin/AAJ-8836-2020; Yoo, Kyung/AAK-8096-2020; Park, Woo Yeong/AGK-9140-2022 | 57203908496; 55899659500; 8310760600; 55038270300; 57204097241; 23388171000; 55125210000; 57037163300; 7403536291; 56603636300; 55880508000; 36344980100; 36994821600; 57217205298; 57194217507; 55568773500; 36162581500; 55662651000 | shine@med.donggukac.kr;shine@med.dongguk.ac.kr; | KIDNEY RESEARCH AND CLINICAL PRACTICE | KIDNEY RES CLIN PRAC | 2211-9132 | 2211-9140 | 41 | 2 | SCIE | UROLOGY & NEPHROLOGY | 2022 | 3 | 36.9 | 0.31 | 2025-06-25 | 2 | 2 | Clinical decision-making; End-of-life care; Life-sustaining treatment; Patient-centered care; Physician preference; Shared; decision-making | FACILITATORS; PREFERENCES; DIALYSIS; BARRIERS; OUTCOMES; REGRET | Clinical decision-making; End-of-life care; Life-sustaining treatment; Patient-centered care; Physician preference; Shared decision-making | adult; aged; Article; clinical decision making; clinical effectiveness; clinical practice; controlled study; cross-sectional study; decision making; Delphi study; doctor patient relationship; education; end of life care; evidence based practice; female; health care; human; Korea; life sustaining treatment; major clinical study; male; middle aged; multicenter study; nephrologist; oncologist; patient care; patient compliance; perception; physician; physician attitude; physician perception; questionnaire; shared decision making; training | English | 2022 | 2022-03 | 10.23876/j.krcp.21.071 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Elderly kidney transplant recipients have favorable outcomes but increased infection-related mortality | Background: The number of elderly patients with end-stage kidney disease has been increasing, but the outcomes of kidney transplants (KT) remain poorly understood in elderly patients. Therefore, we evaluated the clinical outcomes of elderly KT recipients and analyzed the impact of elderly donors. Methods: This retrospective cohort study included patients who underwent KT between 2000 and 2019. KT recipients were divided into four groups according to a combination of recipient and donor age (>= 60 or < 60 years); elderly recipients: old-to-old (n = 46) and young-to-old (n = 83); young recipients: old-to-young (n = 98) and young-to-young (n = 796). We compared the risks of mortality, graft failure, and acute rejection between groups using Cox regression analysis. Results: The incidence of delayed graft function, graft failure, and acute rejection was not different among groups. Annual mean tacrolimus trough level was not lower in elderly recipients than young recipients during 10-year follow-up. Mortality was significantly higher in elderly recipients (p = 0.001), particularly infection-related mortality (p < 0.001). In multivariable Cox regression analysis, old-to-old and young-to-old groups had increased risk of mortality (adjusted hazard ratio [aHR], 2.89; 95% confidence interval [CI], 1.14-7.32; p = 0.03; aHR, 3.06; 95% CI, 1.51-6.20; p = 0.002). However, graft failure and acute rejection risks were not increased in elderly recipients. Conclusion: In elderly recipients, graft survival and acute rejection-free survival were not inferior to those of young recipients. However, mortality, especially risk of infection-related death, was increased in elderly recipients. Thus, low immunosuppression intensity might help decrease mortality in elderly recipients. | Lim, Jeong-Hoon; Lee, Ga Young; Jeon, Yena; Jung, Hee-Yeon; Choi, Ji-Young; Cho, Jang-Hee; Park, Sun-Hee; Kim, Yong-Lim; Kim, Hyung-Kee; Huh, Seung; Yoo, Eun Sang; Won, Dong-II; Kim, Chan-Duck | Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Internal Med, Daegu, South Korea; Kyungpook Natl Univ, Dept Stat, Coll Nat Sci, Daegu, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Surg, Daegu, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Urol, Daegu, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Clin Pathol, Daegu, South Korea | ; Park, Sun-Hee/LMN-0033-2024; Kim, Yong-Lim/AGK-3172-2022; Lim, Jeong-Hoon/ABE-6003-2020; Kim, Hyung-Kee/JBR-8125-2023; Jung, Hee-Yeon/AFB-8578-2022; Lee, Seung Eun/ABG-1607-2021; Cho, Jang-hee/ABD-3534-2020 | 55360244300; 57219960739; 57209909350; 57196396467; 7501393222; 7403536291; 7501831741; 55633533600; 35169819900; 7101832929; 7006609239; 7005166517; 8558530700 | drcdkim@knu.ac.kr; | KIDNEY RESEARCH AND CLINICAL PRACTICE | KIDNEY RES CLIN PRAC | 2211-9132 | 2211-9140 | 41 | 3 | SCIE | UROLOGY & NEPHROLOGY | 2022 | 3 | 36.9 | 2.03 | 2025-06-25 | 14 | 13 | Aged; Graft rejection; Graft survival; Kidney transplantation; Mortality; Transplant donors; Transplant recipients | LIVING DONOR AGE; RENAL-TRANSPLANTATION; CLINICAL-OUTCOMES; DIALYSIS; IMMUNOSUPPRESSION; SURVIVAL; REGISTRY; PATIENT; OLDER; LIFE | Aged; Graft rejection; Graft survival; Kidney transplantation; Mortality; Transplant donors; Transplant recipients | azathioprine; basiliximab; creatinine; cyclosporine; mycophenolate mofetil; sirolimus; steroid; tacrolimus; adult; aged; Article; clinical outcome; cohort analysis; controlled study; delayed graft function; desensitization; diabetes mellitus; estimated glomerular filtration rate; female; follow up; glomerulonephritis; graft failure; graft recipient; graft rejection; HLA typing; human; hypertension; immunosuppressive treatment; incidence; infection; intermediate risk patient; kidney biopsy; kidney transplantation; major clinical study; male; mortality; mortality risk; organ donor; retrospective study; risk assessment | English | 2022 | 2022-05 | 10.23876/j.krcp.21.207 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Long-term risk of all-cause mortality in live kidney donors: a matched cohort study | Background: Long-term outcomes of live kidney donors remain controversial, although this information is crucial for selecting potential donors. Thus, this study compared the long-term risk of all-cause mortality between live kidney donors and healthy control. Methods: We performed a retrospective cohort study including donors from seven tertiary hospitals in South Korea. Persons who underwent voluntary health screening were included as controls. We created a matched control group considering age, sex, era, body mass index, baseline hypertension, diabetes, estimated glomerular filtration rate, and dipstick albuminuria. The study outcome was progression to end-stage kidney disease (ESKD), and all-cause mortality as identified in the linked claims database. Results: We screened 1,878 kidney donors and 78,115 health screening examinees from 2003 to 2016. After matching, 1,701 persons remained in each group. The median age of the matched study subjects was 44 years. and 46.6% were male. Among the study subjects, 2.7% and 16.6% had underlying diabetes and hypertension, respectively. There were no ESKD events in the matched donor and control groups. There were 24 (1.4%) and 12 mortality cases (0.7%) in the matched donor and control groups, respectively. In the age-sex adjusted model, the risk for all-cause mortality was significantly higher in the donor group than in the control group. However, the significance was not retained after socioeconomic status was included as a covariate (adjusted hazard ratio, 1.82; 95% confidence interval, 0.87-3.80). Conclusion: All-cause mortality was similar in live kidney donors and matched non-donor healthy controls with similar health status and socioeconomic status in the Korean population. | Kang, Eunjeong; Park, Sehoon; Park, Jina; Kim, Yaerim; Park, Minsu; Kim, Kwangsoo; Kim, Hyo Jeong; Han, Miyeun; Cho, Jang-Hee; Lee, Jung Pyo; Lee, Sik; Kim, Soo Wan; Park, Sang Min; Chae, Dong-Wan; Chin, Ho Jun; Kim, Yong Chul; Kim, Yon Su; Choi, Insun; Lee, Hajeong | Ewha Womans Univ, Coll Med, Seoul Hosp, Dept Internal Med, Seoul, South Korea; Seoul Natl Univ, Dept Biomed Sci, Coll Med, Seoul, South Korea; Korea Univ, Dept Biostat, Coll Med, Seoul, South Korea; Keimyung Univ, Dept Internal Med, Dongsan Hosp, Daegu, South Korea; Keimyung Univ, Dept Stat, Daegu, South Korea; Seoul Natl Univ Hosp, Transdisciplinary Dept Med & Adv Technol, Seoul, South Korea; Natl Evidence Based Healthcare Collaborating Agcy, Div Healthcare Technol Assessment Res, Seoul, South Korea; Hallym Univ, Dept Internal Med, Hangang Sacred Heart Hosp, Seoul, South Korea; Kyungpook Natl Univ Hosp, Dept Internal Med, Daegu, South Korea; Seoul Natl Univ, Dept Internal Med, Boramae Med Ctr, Seoul, South Korea; Jeonbuk Natl Univ Hosp, Dept Internal Med, Jeonju, South Korea; Chonnam Natl Univ Hosp, Dept Internal Med, Gwangju, South Korea; Seoul Natl Univ Hosp, Dept Family Med, Seoul, South Korea; Seoul Natl Univ, Dept Internal Med, Bundang Hosp, Seongnam, South Korea; Seoul Natl Univ Hosp, Dept Internal Med, 101 Daehak Ro, Seoul 03080, South Korea | Kim, Yong/L-8653-2019; Kim, Dae/AAJ-7518-2021; Cho, Jang-hee/ABD-3534-2020; Lee, Jun-Young/N-5963-2019; Park, Sang/V-9194-2019; Chae, Dong-Wan/J-5681-2012; Kim, Sang/J-5399-2012; Lee, Hyo/G-6299-2019; Kim, Nan/T-8627-2019; Chin, Ho/J-5678-2012 | 56577278700; 57210030734; 57221837324; 57202790600; 57201652582; 57210575084; 57476930200; 55899659500; 7403536291; 56028990400; 57192521521; 56108124300; 58509146900; 23471686900; 23495522400; 57026583000; 7410205767; 57311279600; 36554389800 | mdhjlee@gmail.com; | KIDNEY RESEARCH AND CLINICAL PRACTICE | KIDNEY RES CLIN PRAC | 2211-9132 | 2211-9140 | 41 | 1 | SCIE | UROLOGY & NEPHROLOGY | 2022 | 3 | 36.9 | 0 | 2025-06-25 | 0 | 0 | End-stage kidney disease; Living donors; Mortality; Risk assessment; Prognosis | SERUM PHOSPHORUS; FOLLOW-UP; POPULATION; PREVALENCE; CREATININE; EQUATION; DISEASE; AGE | End-stage kidney disease; Living donors; Mortality; Prognosis; Risk assessment | creatinine; hemoglobin; uric acid; adult; albuminuria; all cause mortality; Article; body mass; cohort analysis; controlled study; diabetes mellitus; diastolic blood pressure; end stage renal disease; estimated glomerular filtration rate; female; human; hypertension; kidney donor; laparoscopy; living donor; major clinical study; male; middle aged; observational study; prognosis; retrospective study; risk assessment; risk factor; social status; systolic blood pressure; tertiary care center | English | 2022 | 2022-01 | 10.23876/j.krcp.21.042 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Letter | Successful provision of hemodialysis to patients with confirmed COVID-19 in Korea: the role of a cooperative network between public and private medical systems | Choi, Ji-Young; Lim, Jeong-Hoon; Han, Seungyeup; Park, Seung-Chan; Jung, Hee-Yeon; Cho, Jang-Hee; Kim, Chan -Duck; Kim, Yong -Lim; Park, Sun-Hee | Kyungpook Natl Univ, Sch Med, Dept Internal Med, 80 Gukchaebosang Ro, Daegu 41944, South Korea; Keimyung Univ, Dept Internal Med, Coll Med, Daegu, South Korea; Daegu Vet Hosp, Dept Internal Med, Daegu, South Korea | Park, Sun-Hee/LMN-0033-2024; Han, Seung Seok/HGD-2825-2022; Kim, Yong-Lim/AGK-3172-2022; Cho, Jang-hee/ABD-3534-2020; Lim, Jeong-Hoon/ABE-6003-2020; Jung, Hee-Yeon/AFB-8578-2022 | 7501393222; 55360244300; 24281360600; 57061182600; 57196396467; 7403536291; 8558530700; 55633533600; 7501831741 | sh-park@knu.ac.kr; | KIDNEY RESEARCH AND CLINICAL PRACTICE | KIDNEY RES CLIN PRAC | 2211-9132 | 2211-9140 | 41 | 6 | SCIE | UROLOGY & NEPHROLOGY | 2022 | 3 | 36.9 | 0.6 | 2025-06-25 | 1 | 1 | antipyretic agent; adult; aged; coronavirus disease 2019; end stage renal disease; female; fever; health care facility; health care organization; health care policy; health service; hemodialysis; hospitalization; human; intensive care unit; Letter; major clinical study; male; nurse; outpatient; peritoneal dialysis; practice guideline; public health service; quarantine; rhinorrhea; SARS-CoV-2 Delta; SARS-CoV-2 Omicron; Severe acute respiratory syndrome coronavirus 2; sore throat; virus transmission | English | 2022 | 2022-11 | 10.23876/j.krcp.22.102 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||||
| ○ | ○ | Editorial Material | The effects of nitric oxide and 8-iso-prostaglandin F2α on chloride absorption in cortical thick ascending limb | Kwon, Tae-Hwan | Kyungpook Natl Univ, Dept Biochem & Cell Biol, Sch Med, Daegu, South Korea | ; Kwon, Tae-Hwan/ABA-1981-2020 | 7202206089 | thkwon@knu.ac.kr; | KIDNEY RESEARCH AND CLINICAL PRACTICE | KIDNEY RES CLIN PRAC | 2211-9132 | 2211-9140 | 41 | 6 | SCIE | UROLOGY & NEPHROLOGY | 2022 | 3 | 36.9 | 0 | 2025-06-25 | 0 | 0 | SODIUM TRANSPORTERS; MECHANISM; NKCC2 | 8 isoprostaglandin F2 alpha; adenosine triphosphatase (potassium sodium); aquaporin; chloride; insulin; mineralocorticoid; nitric oxide; sodium glucose cotransporter 2; sodium phosphate cotransporter 2a; solute carrier family 9; unclassified drug; vasopressin; chronic kidney failure; cortical thickness (bone); drug absorption; Editorial; endothelial dysfunction; epithelium cell; estimated glomerular filtration rate; human; hypercalcemia; hypertension; hypokalemia; kidney distal tubule; limb; liver cirrhosis; protein phosphorylation; pseudohypoaldosteronism; renin angiotensin aldosterone system; sodium transport; upregulation | English | 2022 | 2022-11 | 10.23876/j.krcp.22.179 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Vinyl-addition polymerizations of norbornene and methyl methacrylate by the palladium(II) complexes ligated by 2-iminomethylquinoline and 2-iminomethylpyridine derivatives | Novel Pd(II) complexes, namely, [LnPdCl2] (L-n = L-A and L-B), where L-A is (E)-3-methoxy-N-(quinolin-2-ylmethylene)propan-1-amine and L-B is (E)-N-(pyridin-2-ylmethylene)hexan-1-amine, were synthesized and characterized. X-ray diffraction studies revealed distorted square planar geometries around the Pd(II) center in [LnPdCl2] (L-n = L-A and L-B). The catalytic capabilities of the synthesized complexes were tested in vinyl addition polymerization of norbornene (NB) in the presence of the cocatalyst modified methylaluminoxane (MMAO), displaying high activities with conversions >= 94% in chlorobenzene at 25 ?. The complex [LBPdCl2] displayed the highest activity of up to 4.40 x 106 gPNB mol Pd-1 h-1 at 25 ?C, generating insoluble polynorbornene (PNB) at an NB/Al/Pd ratio of 8,000:500:1. In addition, preliminary methyl methacrylate (MMA) polymerization studies of the [LnPdCl2]/MMAO system demonstrated that the activities toward polar vinyl monomer production were in the range of 8.00 x 104 to 8.20 x 10(4) gPMMA mol Pd-1 h(-1) at 60 ?, yielding a high-molecular-weight syndiotactic poly(methyl methacrylate) (PMMA, M-w = 1.89 x 10(6) g mol(-1)). | Kim, Kyeonghun; Nayab, Saira; Jeong, Ah Rim; Cho, Yerim; Yeo, Hyeonuk; Lee, Hyosun | Kyungpook Natl Univ, Green Nano Mat Res Ctr, Dept Chem, 80 Daehakro, Bukgu, Daegu 41566, South Korea; Shaheed Benazir Bhutto Univ, Dept Chem, Khyber Pakhtunkhwa 18000, Pakistan; Kyungpook Natl Univ, Dept Chem Educ, Dept Pharm, 80 Daehakro, Bukgu, Daegu 41566, South Korea | Yeo, Hyeonuk/AHE-0397-2022; Nayab, Saira/JBS-3013-2023; yeo, hyeonuk/G-7890-2017 | 57221464273; 36490286400; 57705272900; 57565597400; 55324816500; 15750846000 | drnayab@sbbu.edu.pk;hyosunlee@knu.ac.kr; | INORGANICA CHIMICA ACTA | INORG CHIM ACTA | 0020-1693 | 1873-3255 | 539 | SCIE | CHEMISTRY, INORGANIC & NUCLEAR | 2022 | 2.8 | 36.9 | 0.59 | 2025-06-25 | 5 | 6 | Iminomethylquinoline; Iminomethylpyridine; Palladium complexes; Square planar geometry; Polynorbornene; Syndiotactic poly(methyl methacrylate) | N-SUBSTITUTED 2-IMINOMETHYLPYRIDINE; RAC-LACTIDE; METAL-CATALYSTS; NEUTRAL NICKEL; BEHAVIOR; LIGANDS; COPOLYMERIZATION | Iminomethylpyridine; Iminomethylquinoline; Palladium complexes; Polynorbornene; Square planar geometry; Syndiotactic poly(methyl methacrylate) | Acrylic monomers; Aluminum; Esters; Geometry; Palladium compounds; Polymerization; Synthesis (chemical); Iminomethylpyridine; Iminomethylquinoline; Methyl methacrylates; Norbornenes; Palladium complexes; Polynorbornenes; Square planar geometry; Syndiotactic poly(methyl methacrylate); Vinyl-addition polymerization; Chlorine compounds | English | 2022 | 2022-09-01 | 10.1016/j.ica.2022.121025 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Perspectives of patients, family members, health professionals and the public on the impact of COVID-19 on mental health | Background The coronavirus (COVID-19) pandemic has seen a global surge in anxiety, depression, post-traumatic stress disorder (PTSD), and stress. Aims This study aimed to describe the perspectives of patients with COVID-19, their family, health professionals, and the general public on the impact of COVID-19 on mental health. Methods A secondary thematic analysis was conducted using data from the COVID-19 COS project. We extracted data on the perceived causes and impact of COVID-19 on mental health from an international survey and seven online consensus workshops. Results We identified four themes (with subthemes in parenthesis): anxiety amidst uncertainty (always on high alert, ebb and flow of recovery); anguish of a threatened future (intense frustration of a changed normality, facing loss of livelihood, trauma of ventilation, a troubling prognosis, confronting death); bearing responsibility for transmission (fear of spreading COVID-19 in public; overwhelming guilt of infecting a loved one); and suffering in isolation (severe solitude of quarantine, sick and alone, separation exacerbating grief). Conclusion We found that the unpredictability of COVID-19, the fear of long-term health consequences, burden of guilt, and suffering in isolation profoundly impacted mental health. Clinical and public health interventions are needed to manage the psychological consequences arising from this pandemic. | Gardiner, Evangeline; Baumgart, Amanda; Tong, Allison; Elliott, Julian H.; Azevedo, Luciano Cesar; Bersten, Andrew; Cervantes, Lilia; Chew, Derek P.; Cho, Yeoungjee; Crowe, Sally; Douglas, Ivor S.; Evangelidis, Nicole; Flemyng, Ella; Horby, Peter; Howell, Martin; Lee, Jaehee; Lorca, Eduardo; Lynch, Deena; Marshall, John C.; Gonzalez, Andrea Matus; McKenzie, Anne; Manera, Karine; Mehta, Sangeeta; Mer, Mervyn; Morris, Andrew Conway; Nseir, Saad; Povoa, Pedro; Reid, Mark; Sakr, Yasser; Shen, Ning; Smyth, Alan R.; Snelling, Tom; Strippoli, Giovanni F. M.; Teixeira-Pinto, Armando; Torres, Antoni; Viecelli, Andrea K.; Webb, Steve; Williamson, Paula R.; Woc-Colburn, Laila; Zhang, Junhua; Craig, Jonathan C. | Univ Sydney, Sydney Sch Publ Hlth, Sydney, NSW, Australia; Childrens Hosp Westmead, Ctr Kidney Res, Sydney, NSW, Australia; Monash Univ, Sch Publ Hlth & Prevent Med, Cochrane Australia, Melbourne, Vic, Australia; Hosp Sirio Libanes, Dept Crit Care Med, Sao Paulo, Brazil; Flinders Univ S Australia, Coll Med & Publ Hlth, Adelaide, SA, Australia; Denver Hlth, Dept Med, Denver, CO USA; Princess Alexandra Hosp, Dept Nephrol, Brisbane, Qld, Australia; Crowe Associates Ltd, Thame, Oxon, England; Denver Hlth, Sch Med Denver, Dept Med Pulm Sci & Crit Care, Denver, CO USA; Univ Colorado Anschutz, Boulder, CO USA; Cochrane, Editorial & Methods Dept, London, England; Univ Oxford, Nuffield Dept Med, Oxford, England; Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu, South Korea; Univ Chile, Fac Med, Dept Internal Med, Santiago, Chile; Jonze Soc, Brisbane, Qld, Australia; Univ Toronto, Dept Surg, Toronto, ON, Canada; Telethon Kids Inst, Perth, WA, Australia; Univ Toronto, Dept Med, Toronto, ON, Canada; Univ Toronto, Interdept Div Crit Care Med, Toronto, ON, Canada; Univ Witwatersrand, Charlotte Maxeke Johannesburg Acad Hosp, Dept Med, Div Crit Care & Pulmonol, Johannesburg, South Africa; Univ Witwatersrand, Fac Hlth Sci, Johannesburg, South Africa; Univ Cambridge, Dept Med, Cambridge, England; CHU Lille, Crit Care Ctr, Lille, France; Lille Univ, Lille, France; Univ Nova Lisboa, Sao Francisco Xavier Hosp, Nova Med Sch, Polyvalent Intens Care Unit,CHLO,CHRC, Lisbon, Portugal; OUH Odense Univ Hosp, Ctr Clin Epidemiol, Odense, Denmark; OUH Odense Univ Hosp, Res Unit Clin Epidemiol, Odense, Denmark; Jena Univ Hosp, Dept Anesthesiol & Intens Care, Jena, Germany; Peking Univ, Dept Resp Med, Hosp 3, Beijing, Peoples R China; Univ Nottingham, Sch Med, Evidence Based Child Hlth Grp, Nottingham, England; Univ Bari, Dept Emergency & Organ Transplantat, Bari, Italy; Univ Barcelona UB, Hosp Clin Barcelona, Dept Pulmonol, CIBERES,IDIBAPS,Resp Intitute, Barcelona, Spain; Univ Liverpool, Dept Biostat, Liverpool, Merseyside, England; Emory Univ Hosp, Dept Infect Dis, 1364 Clifton Rd NE, Atlanta, GA 30322 USA; Tianjin Univ Tradit Chinese Med, Evidence Based Med Ctr, Tianjin, Peoples R China | Cho, Yeoungjee/G-6176-2013; Lee, Yoojin/AAB-9799-2022; Viecelli, Andrea/G-6966-2017; Gonzalez, Andrea/HDM-9987-2022; Zhang, Junhua/AAZ-7434-2021; Lee, Jaehee/S-1697-2018; Teixeira-Pinto, Armando/H-7947-2013; Azevedo, Luciano/H-2652-2012; , Paula/B-6425-2016; Craig, Jonathan/E-2813-2013; McGee, Richard/C-6117-2009; Smyth, Alan/MFJ-6463-2025; Manera, Karine/ABH-9074-2020; Peter, Horby/D-1585-2013; McKenzie, Anne/K-5912-2015; Snelling, Tom/Y-2162-2019; Williamson, Paula/B-6425-2016; Gardiner, Evangeline/LJM-2410-2024; Flemyng, Ella/HPD-8542-2023; Douglas, Ivor/AAC-6245-2021; Torres, Antoni/H-6128-2017; Woc-Colburn, Laila/U-7357-2019 | 57640072700; 57208129702; 23020354400; 7402852244; 7005936833; 7003508148; 37109443800; 7102026332; 35182599800; 36088780600; 7005619134; 56850401300; 57191337554; 57221724719; 36004603200; 13805476000; 6602282714; 57219456938; 18536499900; 57219087890; 35983718700; 57193948923; 7401670721; 6603492314; 59157733200; 6602214576; 6602772147; 8641382000; 7801690639; 15133087500; 7103344712; 16032438700; 36057430000; 6602574836; 57205521091; 38362587800; 24774575800; 57197397371; 23007146500; 55720332300; 7401926037 | egar5438@uni.sydney.edu.au; | JOURNAL OF MENTAL HEALTH | J MENT HEALTH | 0963-8237 | 1360-0567 | 31 | 4 | SSCI | PSYCHOLOGY, CLINICAL | 2022 | 3.3 | 37.0 | 0.58 | 2025-06-25 | 3 | 5 | COVID-19; SARS-CoV-2; depression; anxiety; PTSD | PSYCHOSOCIAL IMPACT; OUTBREAK | anxiety; COVID-19; depression; PTSD; SARS-CoV-2 | Anxiety; COVID-19; Depression; Family; Humans; Mental Health; SARS-CoV-2; adult; aged; anxiety; Article; coronavirus disease 2019; family health; fear; female; grief; guilt; health practitioner; home quarantine; human; major clinical study; male; mental health; prognosis; Severe acute respiratory syndrome coronavirus 2; thematic analysis; uncertainty; virus transmission; depression; epidemiology; family; mental health; psychology | English | 2022 | 2022-07-04 | 10.1080/09638237.2021.2022637 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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