연구성과로 돌아가기
2020 연구성과 (140 / 270)
※ 컨트롤 + 클릭으로 열별 다중 정렬 가능합니다.
Excel 다운로드
| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ○ | ○ | Letter | Oncological outcomes of omitting sentinel lymph node biopsy in elderly patients with breast cancer | Lee, Jeeyeon; Noh, Jeongju; Jeong, Ji Yun | Kyungpook Natl Univ, Sch Med, Dept Surg, Daegu, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Pathol, Daegu, South Korea | 37079213100; 57218509343; 57205472984 | jyjeong@knu.ac.kr; | ASIAN JOURNAL OF SURGERY | ASIAN J SURG | 1015-9584 | 0219-3108 | 43 | 11 | SCIE | SURGERY | 2020 | 2.767 | 40.1 | 0 | 2025-06-25 | 0 | 0 | Age Factors; Aged; Aged, 80 and over; Breast Neoplasms; Female; Follow-Up Studies; Humans; Mastectomy, Segmental; Neoplasm Recurrence, Local; Organ Sparing Treatments; Sentinel Lymph Node Biopsy; Treatment Outcome; adverse event; age; aged; breast tumor; conservative treatment; epidemiology; female; follow up; human; partial mastectomy; pathology; procedures; sentinel lymph node biopsy; treatment outcome; tumor recurrence; very elderly | English | 2020 | 2020-11 | 10.1016/j.asjsur.2020.07.009 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||||
| ○ | ○ | Article | Comparative Transcriptome Analysis Reveals Gene Regulatory Mechanism of UDT1 on Anther Development | The tapetum plays a crucial role in pollen development by nursing and releasing the microspore. The tapetum undergoes programmed cell death (PCD), and appropriate timing of PCD is essential for microsporogenesis. Undeveloped Tapetum1 (UDT1) is known to function in anther development, but the regulation mechanism of tapetum differentiation and degeneration by UDT1 is largely unknown. Through comparative transcriptome analysis, we selected 100 genes as udt1 downregulated genes. The biological process related to the negative regulation of translation is the most enriched in udt1 downregulated genes. It is attributed by ribosome inactivating proteins (RIPs), but the role of RIPs is not well defined, and they are assumed to participate in tapetal PCD. Lipid transport is another overrepresented Gene Ontology (GO) term in udt1 downregulated genes, indicating the functional loss of the tapetum as the nursing cell. Using comparative analysis and real-time PCR, we infer that UDT1 can trigger tapetal PCD by controlling the expression of RIPs and three aspartyl proteases (AP) grouped with OsAP37, which is well known as being involved in tapetum degeneration. | Moon, Sunok; Hong, Woo-Jong; Kim, Yu-Jin; Chandran, Anil Kumar Nalini; Gho, Yun-Shil; Yoo, Yo-Han; Van Ngoc Tuyet Nguyen; An, Gynheung; Park, Soon Ki; Jung, Ki-Hong | Kyung Hee Univ, Grad Sch Biotechnol, Yongin 17104, South Korea; Kyung Hee Univ, Crop Biotech Inst, Yongin 17104, South Korea; Kyungpook Natl Univ, Sch Appl Biosci, Daegu 41566, South Korea | Jung, Ki/L-5570-2019; Kim, YuJin/NQE-8241-2025; Hong, Woo-Jong/HPF-0756-2023 | 7401616474; 57194418669; 57074286200; 55872105000; 57194218098; 56549465800; 56495682300; 7102580545; 8055974900; 56022522000 | psk@knu.ac.kr;khjung2010@khu.ac.kr; | JOURNAL OF PLANT BIOLOGY | J PLANT BIOL | 1226-9239 | 1867-0725 | 63 | 4 | SCIE | PLANT SCIENCES | 2020 | 2.434 | 40.2 | 1.46 | 2025-06-25 | 16 | 17 | UDT1; Down-stream gene; Programmed cell death; Aspartic protease; Anther; Rice | TAPETUM-DEGENERATION-RETARDATION; MALE REPRODUCTIVE DEVELOPMENT; GENOME-WIDE ANALYSIS; CELL-DEATH; ASPARTIC PROTEASES; POLLEN DEVELOPMENT; DEFECTIVE TAPETUM; RICE; PROTEIN; IDENTIFICATION | Anther; Aspartic protease; Down-stream gene; Programmed cell death; Rice; UDT1 | English | 2020 | 2020-08 | 10.1007/s12374-020-09250-w | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Identification of New Mutant Alleles ofAugminSubunits Broadens Spectrum ofAugminFunction During Sexual Reproduction in Arabidopsis | In flowering plants, production of functional gametophytes is prerequisite for the double fertilization that leads to successful proliferation. Pollen grains as male gametophytes inArabidopsis thalianaare uniquely patterned with two sperm cells inside a vegetative cell. To better understand the genetic regulation underlying pollen development, we morphologically screened DAPI-stained mature pollen in a mutant population generated using an activation tagging vector in this study. As a result, we identified two independent lines,AL318andAL434,exhibiting similar mutant phenotypes regarding nucleus number and pollen pattern. Genetic analysis showed that the two mutants are maintained in heterozygotes but not in homozygotes, due to highly reduced genetic transmission from both sexes. Developmental analysis revealed that mutant microspores at the polarized stage either completely fail to enter pollen mitosis I, or abnormally divide with altered division asymmetry, resulting in mature pollen without the male germline. We found that these defects arise from genetic lesions in theAUG2andAUG4genes, members of the augmin complex that mediates microtubule (MT)-dependent MT nucleation in a broad range of species. Collectively, our study provides genetic evidence that the augmin complex plays a critical role in mitotic entry and proper execution for pollen mitosis I, broadening the spectrum of augmin function during sexual reproduction in Arabidopsis. | Torutaeva, Elnura; Oh, Sung- Aeong; Park, Soon Ki | Kyungpook Natl Univ, Sch Appl Biosci, Daegu 41566, South Korea | 56584560700; 7404104444; 8055974900 | psk@knu.ac.kr; | JOURNAL OF PLANT BIOLOGY | J PLANT BIOL | 1226-9239 | 1867-0725 | 63 | 6 | SCIE | PLANT SCIENCES | 2020 | 2.434 | 40.2 | 0.1 | 2025-06-25 | 2 | 2 | Arabidopsis; Augmin; Cell fate segregation; Microtubule nucleation; Mitotic entry; Pollen mitosis I | MICROTUBULE ORGANIZATION; GAMMA-TUBULIN; CORTICAL MICROTUBULES; SIDECAR-POLLEN; FUSED KINASE; PROTEIN; AUGMIN; DIVISION; SPINDLE; CYTOKINESIS | Arabidopsis; Augmin; Cell fate segregation; Microtubule nucleation; Mitotic entry; Pollen mitosis I | English | 2020 | 2020-12 | 10.1007/s12374-020-09276-0 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Insights from Chloroplast DNA into the Progenitor-Derivative Relationship BetweenCampanula punctataandC. takesimana(Campanulaceae) in Korea | Of the nearly 40 endemics present on Ulleung Island,Campanula takesimanaNakai represents an anagenetically derived lineage of a continental progenitor,C. punctataLam. Other than its low morphological divergence, little is known about the genetic diversity and population structure of the species pair or the geographical origin ofC. takesimana. We sampled a total of 240 accessions in 22 populations, including one Dokdo Island population, of the two species, sequenced four noncoding chloroplast regions (rps16-trnK,trnQ-rps16,psbD-trnT, andpsbM-trnD; 4482 bp), and assessed the genetic consequences of anagenetic speciation. Based on chloroplast DNA, we found substantially lower genetic diversity statistics forC. takesimanacompared to its progenitor, significant population genetic structuring in insular derivative species, and significant molecular divergence betweenC. punctataandC. takesimana. Mutually exclusive haplotypes were found in the two species, and the haplotype network suggested that Ulleung Island haplotypes were derived from the Dokdo Island haplotype, which was originally derived from aC. punctatapopulation in Bonghwa-gun, Gyeongsangbuk-do Province. This study pinpoints a very narrow geographical source area and suggests the potentially important role of Dokdo Island as an initial stepping stone for Ulleung Island endemics. | Cheong, Woo Young; Kim, Seon-Hee; Yang, JiYoung; Lee, Woong; Pak, Jae-Hong; Kim, Seung-Chul | Sungkyunkwan Univ, Dept Biol Sci, 2066 Seobu Ro, Suwon 16419, Gyeonggi Do, South Korea; Kyungpook Natl Univ, Sch Life Sci, Res Inst Dok Do & Ulleung Do Isl, 80 Daehak Ro, Daegu 41566, South Korea | ; Kim, Seung-Chul/AAR-6157-2020 | 57219030799; 57196226213; 55193226000; 57193846823; 7102232932; 57214983739 | sonchus96@skku.edu; | JOURNAL OF PLANT BIOLOGY | J PLANT BIOL | 1226-9239 | 1867-0725 | 63 | 6 | SCIE | PLANT SCIENCES | 2020 | 2.434 | 40.2 | 0.39 | 2025-06-25 | 6 | 6 | Anagenesis; Campanula; Campanulaceae; Dokdo island; Stepping-stone island; Ulleung island | ULLUNG ISLAND; ANAGENETIC SPECIATION; MITOCHONDRIAL-DNA; POPULATION-GROWTH; GENETIC CONSEQUENCES; SEQUENCE; CAMPANULACEAE; SAPINDACEAE; EVOLUTION; PATTERNS | Anagenesis; Campanula; Campanulaceae; Dokdo island; Stepping-stone island; Ulleung island | English | 2020 | 2020-12 | 10.1007/s12374-020-09281-3 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | NH4⁺ Suppresses NO3⁻-Dependent Lateral Root Growth and Alters Gene Expression and Gravity Response in OsAMT1 RNAi Mutants of Rice (Oryza sativa) | TheAMT1family comprises major ammonium transporters in rice roots. In this study, we utilizedAMT1RNAi mutants (amt1) to explore howAMT1affects NH4+- and NO3--mediated morphological development and NH4+-responsive gene expression in roots. In the presence of NH4+,amt1showed inhibition of NO3-- dependent lateral root development. The inhibitory action of NH(4)(+)on lateral root growth was independent of the NO(3)(-)concentrations supplied toamt1roots. The results of split root assays indicated that NH(4)(+)exerts systemic action in inhibiting NO3--dependent lateral root development inamt1. Further study with NAA and NOA, a potent auxin flux inhibitor, suggested that perturbation of membrane dynamics might not be the primary cause of the inhibitory action of NH(4)(+)on NO3--mediated lateral root growth inamt1mutants. RNA-seq analysis of NH4+-responsive genes showed that approximately half of DEGs observed in wild-type roots were not detected in the DEGs ofamt1roots. Gene ontology enrichment analysis suggested that the expression of specific functional gene groups were affected byamt1during the early response to NH4+. Auxin-responsive gene expression and root gravity responses were altered inamt1. This study demonstrated thatAMT1affects the interactions not only between ammonium and nitrate in lateral root growth but also between auxin and NH(4)(+)in rice roots. | Kumar, Vikranth; Kim, Sung Hoon; Priatama, Ryza A.; Jeong, Jin Hee; Adnan, Moch Rosyadi; Saputra, Bernet Agung; Kim, Chul Min; Je, Byoung Il; Park, Soon Ju; Jung, Ki Hong; Kim, Kyung Min; Xuan, Yuan Hu; Han, Chang-deok | Gyeongsang Natl Univ, Plant Mol Biol & Biotechnol Res Ctr PMBBRC, Div Appl Life Sci, BK21 Plus Program, Jinju 52828, South Korea; Natl Fus Res Inst, Plasma Technol Res Ctr, 37 Dongjangsan Ro, Gunsan 54004, South Korea; Wonkwang Univ, Div Hort Ind, Iksan 54538, South Korea; Pusan Natl Univ, Coll Nat Resource & Life Sci, Dept Hort Biosci, Miryang 50463, South Korea; Wonkwang Univ, Div Biol Sci, Iksan 54538, South Korea; Kyung Hee Univ, Grad Sch Biotechnol, Yongin 17104, South Korea; Kyung Hee Univ, Crop Biotech Inst, Yongin 17104, South Korea; Kyungpook Natl Univ, Coll Agr & Life Sci, Sch Appl Biosci, Daegu 41566, South Korea; Shenyang Agr Univ, Coll Plant Protect, Dongling Rd 120, Shenyang 110866, Peoples R China | ; chandrasekaran, vikranth/HPB-6158-2023; LEE, JIN/Q-3108-2018; Park, Soon Ju/JBI-7640-2023; Priatama, Ryza/AAA-3966-2020; Adnan, Moch Rosyadi/JLL-7453-2023; Chandrasekaran, Vikranth Kumar/HPB-6158-2023; Jung, Ki/L-5570-2019; Kim, Kyung-Min Kim/C-7007-2014 | 35148259900; 57212023730; 55533993800; 57212025087; 57217856951; 57217861761; 55697770700; 9245081000; 9245081200; 56022522000; 34868260300; 13409662300; 7403379593 | xuanyuanhu115@syau.edu.cn;cdhan@gnu.ac.kr; | JOURNAL OF PLANT BIOLOGY | J PLANT BIOL | 1226-9239 | 1867-0725 | 63 | 5 | SCIE | PLANT SCIENCES | 2020 | 2.434 | 40.2 | 0.98 | 2025-06-25 | 11 | 10 | Rice; AMT1; Ammonium; Lateral roots | AMMONIUM; ARABIDOPSIS; INHIBITION; AUXIN; NITROGEN; PLANTS; INFLUX; GRAVITROPISM; ELONGATION; ACTIVATION | Ammonium; AMT1; Lateral roots; Rice | English | 2020 | 2020-10 | 10.1007/s12374-020-09263-5 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Review | Production mechanisms, structural features and post-translational modifications of plant peptides | Accumulated evidence suggests that peptides play diverse roles in various aspects of plant growth and development. Therefore, many research groups have developed and utilized new methods for the identification of peptides in different organisms. Nevertheless, the number and diversity of identified peptides remain lower than expected. In addition, the number of identified peptides is underestimated because of their low endogenous concentrations and, consequently, technical difficulties with their isolation. Additionally, while some types of peptides undergo functional maturation via proteolytic processing or post-translational modifications, which are important for their biological activity, most of the enzymes involved in the maturation of peptides have not yet been identified. Together, these factors indicate that the investigation of peptides is in its beginning stages in plants, as in other organisms. This review summarizes the biosynthesis mechanisms, identification tools, post-translational modifications, and biological functions of plant peptides, and the importance of post-translational modifications in peptide activity. | Lee, Kyu Ho; Kwon, Dae Hwan; Song, Jong Tae; Seo, Hak Soo | Seoul Natl Univ, Coll Agr & Life Sci, Dept Plant Sci, Gwanakro 200, Seoul 151921, South Korea; Kyungpook Natl Univ, Sch Appl Biosci, Daegu 41566, South Korea | 57204416526; 57216938492; 57797134000; 26642769200 | seohs@snu.ac.kr; | JOURNAL OF PLANT BIOLOGY | J PLANT BIOL | 1226-9239 | 1867-0725 | 63 | 4 | SCIE | PLANT SCIENCES | 2020 | 2.434 | 40.2 | 0.05 | 2025-06-25 | 3 | 3 | Plant peptide; Post-translational modification; Proteolytic processing; Upstream open reading frame; microRNA-encoded peptide; Non-ribosomal peptide | SECRETED PEPTIDE; ROOT-GROWTH; TYROSYLPROTEIN SULFOTRANSFERASE; CELL FATE; ARABIDOPSIS; PHYTOSULFOKINE; IDENTIFICATION; HORMONES; PROTEINS; ARABINOSYLTRANSFERASES | microRNA-encoded peptide; Non-ribosomal peptide; Plant peptide; Post-translational modification; Proteolytic processing; Upstream open reading frame | English | 2020 | 2020-08 | 10.1007/s12374-020-09255-5 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Rice Male Gamete Expression Database (RMEDB): A Web Resource for Functional Genomic Studies of Rice Male Organ Development | Oryza sativa (rice) is an economically important crop, which is valued as a staple food source and as genetic model for cereals. Rice production needs to increase substantially to meet the growing global demand. Genetic studies have indicated that anther and pollen development genes can be used as targets to improve yield. Although several genes related to male organ developmental pathways have been characterized, the complete signaling network remains unclear. We used publicly available anther and pollen development transcriptome datasets to identify candidates for functional genomics studies. In addition, we newly generated RNA-Seq data for anther, anther wall and pollen samples with leaf sheath as control to provide the expression data for genes that are not covered by microarray technologies in rice. We constructed a platform, the rice male gamete expression database (RMEDB), comprising microarray and RNA-Seq based 188 transcriptome samples across diverse rice tissues and developmental stages of O. sativa japonica and O. sativa indica. Meta-expression analysis identified genes expressed at specific stages of anther or pollen developments. The functionalities in RMEDB database (https://ricephylogenomics-khu.org/RMEDB/home.php) can serve to identify candidates in male organ development for functional genomic studies of rice. | Chandran, Anil Kumar Nalini; Hong, Woo-Jong; Abhijith, Balachandran; Lee, Jinwon; Kim, Yu-Jin; Park, Soon Ki; Jung, Ki-Hong | Kyung Hee Univ, Grad Sch Biotechnol, Yongin 17104, South Korea; Kyung Hee Univ, Crop Biotech Inst, Yongin 17104, South Korea; Kyungpook Natl Univ, Sch Appl Biosci, Daegu 41566, South Korea | ; Kim, YuJin/NQE-8241-2025; Hong, Woo-Jong/HPF-0756-2023; Jung, Ki/L-5570-2019 | 55872105000; 57194418669; 57205447167; 57210899223; 57074286200; 8055974900; 56022522000 | psk@knu.ac.kr;khjung2010@khu.ac.kr; | JOURNAL OF PLANT BIOLOGY | J PLANT BIOL | 1226-9239 | 1867-0725 | 63 | 6 | SCIE | PLANT SCIENCES | 2020 | 2.434 | 40.2 | 1.27 | 2025-06-25 | 15 | 15 | Database; Functional genomics; Male development; Meta-expression; Rice | FLORAL HOMEOTIC GENES; MALE-STERILITY; POLLEN DEVELOPMENT; ANTHER; METABOLISM; TRANSPORTER; IDENTIFICATION; CONSERVATION; ARABIDOPSIS; REGULATOR | Database; Functional genomics; Male development; Meta-expression; Rice | English | 2020 | 2020-12 | 10.1007/s12374-020-09267-1 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Targeting of Cisplatin-Resistant Melanoma Using a Multivalent Ligand Presenting an Elastin-like Polypeptide | Acquired drug resistance is a common occurrence and the main cause of melanoma treatment failure. Melanoma cells frequently developed resistance against cisplatin during chemotherapy, and thus, targeting delivery systems have been devised to decrease drug resistance, increase therapeutic efficacy, and reduce side effects. We genetically engineered a macromolecular carrier using the recursive directional ligation method that specifically targets cisplatin-resistant (Cis-R) melanoma. This carrier is composed of an elastin-like polypeptide (ELP) and multiple copies of Cis-R melanoma-targeting ligands (M-peptide). The designed M16E108 contains 16 targeting ligands incorporated within an ELP and has an ideal thermal phase transition at 39 degrees C. When treated to melanoma cells, M16E108 specifically accumulated in Cis-R B16F10 melanoma cells and accumulated to a lesser extent in parental B16F10 cells. Consistently, M16E108 exhibited efficient homing and longer retention in tumor tissues in Cis-R melanoma-bearing mice than in parental B16F10 melanoma-bearing mice. Thus, M16E108 was found to display considerable potential as a novel agent that specifically targets cisplatin-resistant melanoma. | Cheon, Sun-Ha; Seo, Bo-Yeon; Lee, Young-Jin; Sim, Dahye; Lee, Seon-Boon; Guruprasath, Padmanaban; Singh, Thoudam Debraj; Lee, Byung-Heon; Sarangthem, Vijaya; Park, Rang-Woon | Kyungpook Natl Univ, Sch Med, Cell & Matrix Res Inst, Dept Biochem & Cell Biol, Daegu 41944, South Korea; All India Inst Med Sci, Dept Med Oncol Lab, New Delhi 110029, India; All India Inst Med Sci, Dept Pathol, New Delhi 110029, India | ; Sarangthem, Vijaya/AAX-7421-2020 | 57191960042; 57191958798; 57191967618; 57213821708; 57219405701; 56721384100; 55190689800; 16304374900; 56001741200; 7401895636 | devi1703@gmail.com;nwpark@knu.ac.kr; | ACS BIOMATERIALS SCIENCE & ENGINEERING | ACS BIOMATER SCI ENG | 2373-9878 | 6 | 9 | SCIE | MATERIALS SCIENCE, BIOMATERIALS | 2020 | 4.749 | 40.2 | 0.36 | 2025-06-25 | 10 | 10 | cisplatin resistance; tumor targeting; multivalent; melanoma; ELP | HUMAN TUMOR XENOGRAFT; VASCULAR-PERMEABILITY; MOLECULAR-MECHANISMS; ACQUIRED-RESISTANCE; INHIBITION; DESIGN | cisplatin resistance; ELP; melanoma; multivalent; tumor targeting | Animals; Cisplatin; Elastin; Ligands; Melanoma; Mice; Peptides; Bearings (machine parts); Cells; Chemotherapy; Cytology; Elastin; Glycoproteins; Ligands; Mammals; Oncology; cisplatin; drug carrier; ligand; polypeptide; cisplatin; elastin; ligand; peptide; B16f10 melanoma cells; Elastin-like polypeptides; Multivalent ligands; Targeting deliveries; Targeting ligands; Therapeutic efficacy; Thermal phase transition; Treatment failure; animal cell; animal experiment; animal model; animal tissue; Article; cancer cell; cancer resistance; cancer size; confocal microscopy; controlled study; ex vivo study; female; genetic engineering; human; human cell; melanoma; melanoma cell; molecular size; molecular weight; mouse; multidrug resistance; nonhuman; particle size; phage display; phase transition; photon correlation spectroscopy; priority journal; protein expression; protein purification; synthesis; transition temperature; animal; genetics; melanoma; Dermatology | English | 2020 | 2020-09 | 10.1021/acsbiomaterials.0c00599 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Selective antibacterial and apoptosis-inducing effects of hybrid gold nanoparticles - A green approach | The development of novel approaches in the biosynthesis of gold nanoparticles has significantly gained tremendous attention in the medical field. In the present study, an aqueous seaweed extract of the marine brown algae S. ilicifolium has been used for the synthesis of hybrid gold nanoparticles. The gold nanoparticles were found to be near-spherical in shape and size of 20-25 nm. Altogether, phytoconstituents such as polyols, proteins, and aromatic compounds play an important role in capping and stabilizing the hybrid gold nanoparticles. The hybrid gold nanoparticles were found to be crystalline as evidence by X-ray diffraction studies. We also demonstrated that synthesized hybrid gold nanoparticles exert antibacterial activity at 48 +/- 1.36 mu g mL(-1) and cause selective cell death of Staphylococcus aureus by generating an enhanced level of intracellular ROS. Further, upon treatment with hybrid gold nanoparticles (24 +/- 1.94 mu gmL(-1)), the breast cancer cell lines showed more apoptotic features such as loss of membrane integrity and chromatin condensation when compared to the control groups. The biocompatibility assessment of hybrid gold nanoparticles in Artemia sauna revealed that it does not elicit any lethal effect even at 250 mu gmL(-1). Taken together, these findings suggest that a hybrid nanoparticle from S. illicifolium is eco-friendly, has selective antibacterial activity, and effectively kills breast cancer cells by inducing apoptosis. | Xavier, Helen Fathima Manuel; Nadar, Vinita Manimaran; Patel, Puja; Umapathy, Devan; Joseph, Antony Velanganni; Manivannan, Selvambigai; Santhiyagu, Prakash; Pandi, Boomi; Muthusamy, Govarthanan; Rathinam, Yuvakkumar; Ponnuchamy, Kumar | Alagappa Univ, Dept Anim Hlth & Management, Food Chem & Mol Canc Biol Lab, Karaikkudi 630003, Tamil Nadu, India; Bharathidasan Univ, Dept Biochem, Tiruchirappalli 620024, Tamil Nadu, India; Univ Sheffield, Dept Biomed Sci, Western Bank, Sheffield S10 2TN, S Yorkshire, England; Univ Sheffield, Ctr Membrane Interact & Dynam CMIAD, Western Bank, Sheffield S10 2TN, S Yorkshire, England; Tamil Nadu Dr J Jayalalithaa Fisheries Univ, Fac Basic Sci, Inst Fisheries Postgrad Studies, OMR Campus, Chennai 603103, Tamil Nadu, India; Alagappa Univ, Dept Bioinformat, Karaikkudi 630003, Tamil Nadu, India; Kyungpook Natl Univ, Dept Environm Engn, Daegu 41566, South Korea; Alagappa Univ, Dept Phys, Nanomat Lab, Sci Campus, Karaikkudi 630003, Tamil Nadu, India | Muthusamy, Govarthanan/C-1491-2014; Manivannan, Selvambigai/IUQ-7979-2023; PRAKASH, SANTHIYAGU/J-8033-2014; Govarthanan, Muthusamy/C-1491-2014; Ponnuchamy, Kumar/D-3470-2013; santhiyagu, prakash/J-8033-2014 | 57218292579; 57218289837; 57204854762; 57209735096; 56545842800; 55806687300; 55020136900; 55191343000; 54881927600; 32267723400; 55173720800 | kumarp@alagappauniversity.ac.in; | JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY | J DRUG DELIV SCI TEC | 1773-2247 | 2588-8943 | 59 | SCIE | PHARMACOLOGY & PHARMACY | 2020 | 3.981 | 40.4 | 1.98 | 2025-06-25 | 24 | 24 | Sargassum illicifolium; Hybrid gold nanoparticles; Apoptosis; Antibacterial; Cell viability | SILVER NANOPARTICLES; SEAWEED; BIOSYNTHESIS; ANTIBIOFILM; TOXICITY | Antibacterial; Apoptosis; Cell viability; Hybrid gold nanoparticles; Sargassum illicifolium | algal extract; gold nanoparticle; reactive oxygen metabolite; animal experiment; antibacterial activity; antineoplastic activity; apoptosis; Artemia salina; Article; biochemical composition; biocompatibility; cell death; chromatin condensation; controlled study; crystal structure; green chemistry; hybrid; nonhuman; particle size; proapoptotic activity; Sargassum; Sargassum illicifolium; X ray diffraction | English | 2020 | 2020-10 | 10.1016/j.jddst.2020.101890 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Pediatric head computed tomography with advanced modeled iterative reconstruction: focus on image quality and reduction of radiation dose | Background Iterative reconstruction has become the standard method for reconstructing computed tomography (CT) scans and needs to be verified for adaptation. Objective To assess the image quality after adapting advanced modeled iterative reconstruction (ADMIRE) for pediatric head CT. Materials and methods We included image sets with filtered back projection reconstruction (the cFBP group, n=105) and both filtered back projection and ADMIRE reconstruction (the lower-dose group, n=109) after dose reduction. All five strength levels of ADMIRE and filtered back projection were adapted for the lower-dose group and compared with the cFBP group. Quantitative parameters including noise, signal-to-noise ratio and contrast-to-noise ratio and qualitative parameters including noise, white matter and gray matter differentiation of the supra- and infratentorial levels, sharpness, artifact, and diagnostic accuracy were also evaluated and compared with interobserver agreement. Results There was a mean dose reduction of 30.6% in CT dose index volume, 32.1% in dose length product, and 32.1% in effective dose after tube current reduction. There was gradual reduction of noise in air, cerebrospinal fluid and white matter with strength levels of ADMIRE from 1 to 5 (P<0.001). Signal-to-noise ratio and contrast-to-noise ratio in all age groups increased among strength levels of ADMIRE, in sequence from 1 to 5, with statistical significance (P<0.001). Gradual reduction of qualitative parameters was noted among strength levels of ADMIRE in sequence from 1 to 5 (P<0.001). Conclusion Use of ADMIRE for pediatric head CT can reduce radiation dose without degrading image quality. | Cho, Hyun-Hae; Lee, So Mi; You, Sun Kyoung | Ewha Womans Univ, Dept Radiol, Mokdong Hosp, 1071 Anyangcheon Ro, Seoul 07985, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Radiol, Daegu, South Korea; Chungnam Natl Univ Hosp, Dept Radiol, Daejeon, South Korea | 56544900900; 56824903400; 56710939300 | picoai@yahoo.co.kr; | PEDIATRIC RADIOLOGY | PEDIATR RADIOL | 0301-0449 | 1432-1998 | 50 | 2 | SCIE | PEDIATRICS;RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | 2020 | 2.505 | 40.7 | 1.38 | 2025-06-25 | 16 | 16 | Brain; Children; Computed tomography; Image quality; Iterative reconstruction; Radiation dose | FILTERED BACK-PROJECTION; ABDOMINAL CT; YOUNG-CHILDREN; PROTOCOLS; ANGIOGRAPHY; ALGORITHM; ROUTINE | Brain; Children; Computed tomography; Image quality; Iterative reconstruction; Radiation dose | Adolescent; Brain; Brain Diseases; Child; Child, Preschool; Female; Humans; Infant; Male; Neuroimaging; Observer Variation; Radiation Dosage; Radiographic Image Interpretation, Computer-Assisted; Reproducibility of Results; Signal-To-Noise Ratio; Tomography, X-Ray Computed; advanced modeled iterative reconstruction; article; artifact; cerebrospinal fluid; child; computer assisted tomography; contrast to noise ratio; controlled study; diagnostic accuracy; diagnostic test accuracy study; filtered back projection; gray matter; groups by age; human; image quality; interrater reliability; low drug dose; major clinical study; quantitative analysis; radiation dose; signal noise ratio; statistical significance; white matter; adolescent; brain; brain disease; computer assisted diagnosis; diagnostic imaging; female; infant; male; neuroimaging; observer variation; preschool child; procedures; reproducibility; x-ray computed tomography | English | 2020 | 2020-02 | 10.1007/s00247-019-04532-z | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Detection of infectious hypodermal and hematopoietic necrosis virus and white spot syndrome virus in whiteleg shrimp (Penaeus vannamei) imported from Vietnam to South Korea | In this study, whiteleg shrimp (Penaeus vannamei) imported from Vietnam were collected from South Korean markets, and examined for 2 viruses: infectious hypodermal and hematopoietic necrosis virus (IHHNV, recently classified as decapod penstyldensovirus-1), and white spot syndrome virus (WSSV). Among 58 samples, we detected IHHNV in 23 samples and WSSV in 2 samples, using polymerase chain reaction and sequencing analyses. This is the first report of IHHNV and WSSV detection in imported shrimp, suggesting that greater awareness and stricter quarantine policies regarding viruses infecting shrimp imported to South Korea are required. | Park, Seul Chan; Choi, Seong-Kyoon; Han, Se-Hyeon; Park, Song; Jeon, Hye Jin; Lee, Seung Chan; Kim, Kyeong Yeon; Lee, Young Seo; Kim, Ji Hyung; Han, Jee Eun | Kyungpook Natl Univ, Coll Vet Med, Lab Aquat Biomed, 80 Daehak Ro, Daegu 41566, South Korea; DGIST, Core Prot Resources Ctr, Daegu 42988, South Korea; DGIST, Div Biotechnol, Daegu 42988, South Korea; Seoul Broadcasting Stn, Dept News Team, Seoul 07574, South Korea; Korea Res Inst Biosci & Biotechnol, Infect Dis Res Ctr, 125 Gwahak Ro, Daejeon 34141, South Korea | ; Kim, Ji Hyung/B-7321-2011 | 57212190350; 55505432500; 57210915063; 57139047900; 57212193058; 57212199348; 57212195103; 57212200636; 57225000204; 57214671240 | kzh81@kribb.re.kr;jehan@knu.ac.kr; | JOURNAL OF VETERINARY SCIENCE | J VET SCI | 1229-845X | 1976-555X | 21 | 2 | SCIE | VETERINARY SCIENCES | 2020 | 1.672 | 40.8 | 1.29 | 2025-06-25 | 13 | 11 | Infectious hypodermal and hematopoietic necrosis virus; white spot syndrome virus; South Korea; quarantine; Vietnam | LITOPENAEUS-VANNAMEI; DISEASE | Infectious hypodermal and hematopoietic necrosis virus; Quarantine; South Korea; Vietnam; White spot syndrome virus | Animals; Densovirinae; Food Microbiology; Penaeidae; Republic of Korea; Seafood; Sequence Analysis, DNA; Vietnam; White spot syndrome virus 1; nonstructural protein 1; nucleic acid; amino acid sequence; Article; classification; geographic origin; Infectious hematopoietic necrosis virus; infectious hypodermal and hematopoietic necrosis virus; nonhuman; nucleic acid analysis; nucleotide sequence; Penaeus vannamei; phylogeny; polymerase chain reaction; sequence analysis; South Korea; Viet Nam; virus detection; White spot syndrome virus; animal; Densovirinae; DNA sequence; food control; isolation and purification; Penaeidae; sea food; veterinary medicine; virology; White spot syndrome virus | English | 2020 | 2020-03 | 10.4142/jvs.2020.21.e31 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Effects of Contact Potential and Sidewall Surface Plane on the Performance of GaN Vertical Nanowire MOSFETs for Low-Voltage Operation | GaN-based materials are expected to show excellent immunity against short-channel effects because they have relatively lower permittivity and higher electron effective mass, compared to other materials such as Si, Ge, and In(Ga)As. To further reduce the short-channel effects, it is important to enhance the gate controllability of the device by utilizing a gate-all-around (GAA) structure. In this article, GaN vertical GAA nanowire MOSFETs with various diameters of 120, 75, and 45 nm have been fabricated. The device with a diameter of 120 nm shows a threshold voltage of 0.7 V, drain saturation voltage of 0.5 V, and subthreshold swing of 70 mV/decade, which would be suitable for low-voltage/power applications. However, the devices with smaller diameters of 75 and 45 nm show peculiar characteristics, such as a second rise of the drain current in output characteristics and a negative transconductance. | Son, Dong-Hyeok; Thingujam, Terirama; Kim, Jeong-Gil; Kim, Dae-Hyun; Kang, In Man; Im, Ki-Sik; Theodorou, Christoforos; Ghibaudo, Gerard; Cristoloveanu, Sorin; Lee, Jung-Hee | Kyungpook Natl Univ, Sch Elect Engn & Comp Sci, Daegu 41566, South Korea; Kumoh Natl Inst Technol, Adv Mat Res Ctr, Gumi 39177, South Korea; Grenoble Polytech Inst, Inst Microelect Electromagnetism & Photon, F-38016 Grenoble, France | Ghibaudo, Gerard/AAF-5820-2021; ghibaudo, gerard/E-9959-2010; Kim, Junghwan/AAQ-9204-2021 | 56681422800; 57194828103; 57203324876; 57212363794; 7203062678; 8679677600; 36023009000; 36048011700; 15076615300; 57196140713 | dhson@ee.knu.ac.kr;trthingujam@gmail.com;jgkims2@ee.knu.ac.kr;dae-hyun.kim@ee.knu.ac.kr;imkang@ee.knu.ac.kr;ksim@kumoh.ac.kr;theodoch@minatec.grenoble-inp.fr;ghibaudo@minatec.inpg.fr;sorin@minatec.grenoble-inp.fr;jlee@ee.knu.ac.kr; | IEEE TRANSACTIONS ON ELECTRON DEVICES | IEEE T ELECTRON DEV | 0018-9383 | 1557-9646 | 67 | 4 | SCIE | ENGINEERING, ELECTRICAL & ELECTRONIC;PHYSICS, APPLIED | 2020 | 2.917 | 40.8 | 0.46 | 2025-06-25 | 8 | 7 | Contact potential; GaN vertical nanowire MOSFET (VNW-MOSFET); low-voltage application; nanowire diameter; negative transconductance (NT) | LOW-FREQUENCY NOISE; CHANNEL | Contact potential; GaN vertical nanowire MOSFET (VNW-MOSFET); Low-voltage application; Nanowire diameter; Negative transconductance (NT) | Drain current; III-V semiconductors; MOSFET devices; Nanowires; Threshold voltage; Transconductance; Contact potential; Electron effective mass; Low voltage operation; Low-voltage applications; MOS-FET; Negative transconductance; Output characteristics; Short-channel effect; Gallium nitride | English | 2020 | 2020-04 | 10.1109/ted.2020.2975599 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Effects of Interface Traps and Self-Heating on the Performance of GAA GaN Vertical Nanowire MOSFET | In the past couple of years, GaN-based vertical FETs have been explored to complement their potential logic applicability along with its well-known advantages in high-power and RF applications. In this article, the performances of short-channel gate-all-around (GAA) GaN vertical nanowire MOSFETs, fabricated for a possible low-voltage logic application, have been investigated via simulation, assuming the multilevel trapping effects at the gate interface and the self-heating effects. The simulation results reveal that shallow traps at the interface increase the OFF-state current, the subthreshold swing, and the drain-induced barrier lowering, while deep traps at the interface lower the ON-state current and cause the threshold voltage instability. When the gate voltage is higher than the flat-band voltage of the nanowire channel in the saturation region of operation, the mobility degradation, related to the self-heating, becomes significant due to the increased incorporation of the optical phonon scattering. | Thingujam, Terirama; Son, Dong-Hyeok; Kim, Jeong-Gil; Cristoloveanu, Sorin; Lee, Jung-Hee | Kyungpook Natl Univ, Sch Elect Engn, Daegu 41566, South Korea; Grenoble Inst Technol, Inst Microelect Electromagnetism & Photon, F-38016 Grenoble, France | 57194828103; 56681422800; 57203324876; 15076615300; 57196140713 | trthingujam@gmail.com;dhson@ee.knu.ac.kr;jgkims2@ee.knu.ac.kr;sorin@minatec.grenoble-inp.fr;jlee@ee.knu.ac.kr; | IEEE TRANSACTIONS ON ELECTRON DEVICES | IEEE T ELECTRON DEV | 0018-9383 | 1557-9646 | 67 | 3 | SCIE | ENGINEERING, ELECTRICAL & ELECTRONIC;PHYSICS, APPLIED | 2020 | 2.917 | 40.8 | 0.68 | 2025-06-25 | 21 | 20 | Gate-all-around (GAA); GaN; interface traps; mobility degradation; TCAD | SILICON | GaN; Gate-all-around (GAA); interface traps; mobility degradation; TCAD | Computer circuits; Drain current; Gallium nitride; III-V semiconductors; MOSFET devices; Nanowires; Threshold voltage; Drain-induced barrier lowering; Gate-all-around; Interface traps; Mobility degradation; Optical phonon scattering; Self-heating effect; TCAD; Threshold-voltage instabilities; Interface states | English | 2020 | 2020-03 | 10.1109/ted.2019.2963427 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Effects of nitrous oxide on glycinergic transmission in rat spinal neurons | We investigated the effects of nitrous oxide (N2O) on glycinergic inhibitory whole-cell and synaptic responses using a "synapse bouton preparation," dissociated mechanically from rat spinal sacral dorsal commissural nucleus (SDCN) neurons. This technique can evaluate pure single- or multi-synaptic responses from native functional nerve endings and enable us to accurately quantify how N2O influences pre- and postsynaptic transmission. We found that 70 % N2O enhanced exogenous glycine-induced whole-cell currents (I-Gly) at glycine concentrations lower than 3 x 10(-5) M, but did not affect IGly at glycine concentrations higher than 10(-4) M. N2O did not affect the amplitude and 1/e decay-time of both spontaneous and miniature glycinergic inhibitory postsynaptic currents recorded in the absence and presence of tetrodotoxin (sIPSCs and mIPSCs, respectively). The decrease in frequency induced by N2O was observed in sIPSCs but not in mIPSCs, which was recorded in the presence of both tetrodotoxin and Cd2+, which block voltage-gated Na+ and Ca2+ channels, respectively. N2O also decreased the amplitude and increased the failure rate and paired-pulse ratio of action potential-evoked glycinergic inhibitory postsynaptic currents. N2O slightly decreased the Ba2+ currents mediated by voltage-gated Ca2+ channels in SDCN neurons. We found that (NO)-O-2 suppresses glycinergic responses at synaptic levels with presynaptic effect having much more predominant role. The difference between glycinergic whole-cell and synaptic responses suggests that extrasynaptic responses seriously modulate whole-cell currents. Our results strongly suggest that these responses may thus in part explain analgesic effects of N2O via marked glutamatergic inhibition by glycinergic responses in the spinal cord. | Nakamura, Michiko; Jang, Il-Sung; Yamaga, Toshitaka; Kotani, Naoki; Akaike, Norio | Kyungpook Natl Univ, Sch Dent, Dept Pharmacol, 2177 Dalgubeol Daero, Daegu 700412, South Korea; Kumamoto Hlth Sci Univ, Res Div Life Sci, Kita Ku, 325 Izumi Machi, Kumamoto 8615598, Japan; Kitamoto Hosp, Res Div Neurophysiol, 3-7-6 Kawarasone, Koshigaya, Saitama 3430821, Japan; Kumamoto Kinoh Hosp, Res Div Clin Pharmacol, Juryo Grp,Med Corp, Kita Ku, 6-8-1 Yamamuro, Kumamoto 8608518, Japan | 36051866000; 7102177910; 35304266700; 56708285400; 57194502749 | akaike.sachin715@juryo.or.jp; | BRAIN RESEARCH BULLETIN | BRAIN RES BULL | 0361-9230 | 1873-2747 | 162 | SCIE | NEUROSCIENCES | 2020 | 4.079 | 40.8 | 0.07 | 2025-06-25 | 1 | 1 | Spinal neurons; Glycinergic transmission; Nitrous oxide; Nerve-bouton preparation; Focal stimulation | DORSAL-HORN NEURONS; D-ASPARTATE RECEPTOR; PRESYNAPTIC INHIBITION; GLUTAMATERGIC TRANSMISSION; COMPETITIVE-INHIBITION; PYRAMIDAL NEURONS; NERVE-TERMINALS; PROPOFOL; CORD; RELEASE | Focal stimulation; Glycinergic transmission; Nerve-bouton preparation; Nitrous oxide; Spinal neurons | Analgesics, Non-Narcotic; Animals; Dose-Response Relationship, Drug; Glycine; Inhibitory Postsynaptic Potentials; Nitrous Oxide; Organ Culture Techniques; Posterior Horn Cells; Rats; Rats, Wistar; Spinal Cord; Synaptic Transmission; barium; glycine; nitrous oxide; tetrodotoxin; voltage gated calcium channel; voltage gated sodium channel; analgesic agent; glycine; nitrous oxide; action potential; animal cell; Article; controlled study; neurotransmission; nonhuman; priority journal; rat; spinal cord nerve cell; whole cell; animal; dose response; drug effect; inhibitory postsynaptic potential; metabolism; organ culture technique; physiology; posterior horn cell; spinal cord; synaptic transmission; Wistar rat | English | 2020 | 2020-09 | 10.1016/j.brainresbull.2020.06.014 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Potential urinary extracellular vesicle protein biomarkers of chronic active antibody-mediated rejection in kidney transplant recipients | The aim of this study was to identify potential proteomic biomarkers for chronic active antibody-mediated rejection (CAMR) in kidney transplant recipients (KTRs). Among 385 KTRs enrolled in a cross-sectional multi center study, 26 KTRs with biopsy-proven CAMR, 57 KTRs with long-term graft survival (LGS), and 10 rejection- free matched KTRs were included. A proteomic approach was employed to measure urinary extracellular vesicle (EV) changes in the KTRs. The urinary EVs were trypsin-digested using a gel-assisted protocol and quantified by label-free liquid chromatography with tandem mass spectrometry, using a data-dependent acquisition (DDA) mode. Western blot analysis was performed to confirm the protein levels for each candidate biomarker. Analysis of the isolated EV proteins revealed 93 and 97 proteins in the CAMR and LGS patients, respectively. Proteins that were identical in both groups were excluded and only high-significance proteins with a fold change of at least 1.5 were selected as candidate biomarkers. Six proteins (APOA1, TTR, PIGR, HPX, AZGP1, and CP) that were distinguishable between CAMR and LGS were selected. The proteins were confirmed by immunoblot analyses using independently acquired urinary EV samples. AZGP1 in particular was found to be a CAMR-specific proteomic biomarker that was distinguishable from the rejection-free control group with matching kidney function, duration of transplantation, and age. We identified and validated six proteomic biomarkers for CAMR and clarified one CAMR-specific proteomic biomarker in KTRs. Further clinical trials are needed before these rejection-specific biomarkers can be applied for the early prediction, diagnosis, and monitoring of the clinical response of KTRs to the treatment of CAMR. | Jung, Hee-Yeon; Lee, Chan-Hyeong; Choi, Ji-Young; Cho, Jang-Hee; Park, Sun-Hee; Kim, Yong -Lim; Moon, Pyong-Gon; Baek, Moon -Chang; Park, Jae Berm; Kim, Yeong Hoon; Chung, Byung Ha; Lee, Sang-Ho; Kim, Chan-Duck | Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Internal Med, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Mol Med, Daegu, South Korea; Samsung Med Ctr, Dept Surg, Seoul, South Korea; Inje Univ, Coll Med, Dept Internal Med, Busan, South Korea; Catholic Univ Korea, Coll Med, St Marys Hosp, Dept Internal Med, Seoul, South Korea; Kyung Hee Univ, Coll Med, Dept Internal Med, Seoul, South Korea | Kim, Yong-Lim/AGK-3172-2022; Kim, Tae-Hee/AAN-9079-2021; Cho, Jang-hee/ABD-3534-2020; Jung, Hee-Yeon/AFB-8578-2022 | 57196396467; 57189904697; 7501393222; 7403536291; 7501831741; 55633533600; 36455020800; 7006013097; 13605451500; 57212676847; 57201863822; 55890136000; 8558530700 | drcdkim@knu.ac.kr; | JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES | J CHROMATOGR B | 1570-0232 | 1873-376X | 1138 | SCIE | BIOCHEMICAL RESEARCH METHODS;CHEMISTRY, ANALYTICAL | 2020 | 3.205 | 40.8 | 1.88 | 2025-06-25 | 42 | 40 | Extracellular vesicle; Biomarkers; Proteomics; Chronic active antibody-mediated rejection; Kidney transplantation | IDENTIFICATION; EXOSOMES; RECEPTOR; PROLIFERATION; NEPHROPATHY; EXPRESSION; PROTEOMICS; SURVIVAL; IGA | Biomarkers; Chronic active antibody-mediated rejection; Extracellular vesicle; Kidney transplantation; Proteomics | Adult; Aged; Biomarkers; Chronic Disease; Cross-Sectional Studies; Extracellular Vesicles; Female; Graft Rejection; Humans; Kidney Transplantation; Male; Middle Aged; Protein Interaction Mapping; Protein Interaction Maps; Proteinuria; Proteome; Proteomics; Antibodies; Diagnosis; Electrophoresis; Liquid chromatography; Mass spectrometry; Molecular biology; apolipoprotein A1; biological marker; ceruloplasmin; hemopexin; secretory component; transthyretin; unclassified drug; zinc alpha 2 glycoprotein 1; biological marker; proteome; Chronic active antibody-mediated rejection; Extracellular; Kidney transplantation; Liquid chromatography with tandem mass spectrometries; Proteomic approaches; Proteomic biomarkers; Proteomics; Western-blot analysis; adult; antibody mediated rejection; Article; controlled study; cross-sectional study; exosome; female; graft recipient; graft survival; human; immunoblotting; kidney graft; liquid chromatography; major clinical study; male; middle aged; multicenter study (topic); priority journal; protein urine level; proteomics; tandem mass spectrometry; Western blotting; adverse event; aged; chemistry; chronic disease; clinical trial; exosome; genetics; graft rejection; kidney transplantation; metabolism; multicenter study; procedures; protein analysis; proteinuria; urine; Biomarkers | English | 2020 | 2020-02-01 | 10.1016/j.jchromb.2019.121958 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
페이지 이동: