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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | Article | Long-term treatment of allogeneic adipose-derived stem cells in a dog with rheumatoid arthritis | Background: Although there are growing demands for stem cell-based therapy for companion animals in various diseases, a few clinical trials have been reported. Moreover, most of them are the results from only one or a few times of stem cell injection. Objectives: The aim of this study is to describe a long-term treatment with allogeneic adipose-derived stem cells (ASCs) in a dog with rheumatoid arthritis (RA), which is a rare canine disease. Methods: The dog with RA received intravascular injection of allogeneic ASCs derived from two healthy donors once a month for 11 months. To assess therapeutic effects of ASCs, orthopedic examination and clinical evaluation was performed. Cytokines of tumor necrosis factor-alpha and interleukin-6 in the plasma were measured using ELISA analysis. Results: Despite this repeated and long-term administration of allogeneic ASCs, there were no side effects such as immunorejection responses or cell toxicity. The orthopedic examination score for the dog decreased after ASCs treatment, and the clinical condition of the dog and owner's satisfaction were very good Conclusions: Although ASCs has been suggested as one of the options for RA treatment because of its anti-inflammatory and immunosuppressive functions, it has never been used to treat RA in dogs. The present report describes a case of canine RA treated with allogeneic ASCs for long-term in which the dog showed clinical improvement without adverse effects. | Seo, Min-Gyeong; Park, Seil; Han, Seonyoung; Kim, Ah-Young; Lee, Eun-Joo; Jeong, Kyu-Shik; Hong, Il-Hwa | Gyeongsang Natl Univ, Coll Vet Med, Dept Vet Pathol, Jinju 52828, South Korea; Yonsei Univ, Coll Med, Cardiovasc Prod Evaluat Ctr, Seoul 03722, South Korea; Kyungpook Natl Univ, Coll Vet Med, Dept Vet Pathol, 80 Daehak Ro, Daegu 41566, South Korea; Gyeongsang Natl Univ, Inst Anim Med, Jinju 52828, South Korea | ; Jeong, Kyu-Shik/D-6740-2011; park, seil/KLD-0847-2024 | ihhong@gnu.ac.kr; | JOURNAL OF VETERINARY SCIENCE | J VET SCI | 1229-845X | 1976-555X | 23 | 4 | SCIE | VETERINARY SCIENCES | 2022 | 1.8 | 34.4 | 6 | Dog; immune -mediated disease; immunomodulation; mesenchymal stem cell | IMMUNE-MEDIATED POLYARTHRITIS; MANAGEMENT; DIAGNOSIS; SAFETY | English | 2022 | 2022-07 | 10.4142/jvs.22069p | 바로가기 | 바로가기 | 바로가기 | |||||||||
| ○ | ○ | Article | Molecular characteristics of ESBL-producing Escherichia coli isolated from chickens with colibacillosis | Background: Avian pathogenic Escherichia coli (APEC) causes colibacillosis, resulting in significant economic losses in the poultry industry. Objectives: In this study, the molecular characteristics of two extended-spectrum beta-lactamase (ESBL)-producing APEC isolates were compared with previously reported ESBL-producing E. coli isolates. Methods: The molecular characteristics of E. coli isolates and the genetic environments of the ESBL genes were investigated using whole genome sequencing. Results: The two ESBL-producing APEC were classified into the phylogenetic groups C and B1 and ST410 and ST162, respectively. Moreover, the ESBL genes of the two isolates were harbored in different Inc plasmids. The EC1809182 strain, harboring the bla(CTX-M-)(55) gene on the plasmid, exhibited extensive homology to IncFIB (98.4%) and IncFIC(FII) (95.8%). The EC1809191 strain, harboring the bla(CTX-M-1) gene, was homologous to IncI1-I (Gamma) (99.3%). All chromosomes carried the multidrug transporter, mdf(A) gene. Mobile genetic elements, adjacent to CTX-M genes, facilitated the dissemination of genes in the two isolates, analogous to other ESBL-producing E. coli isolates. Conclusions: This study clarifies the transmission dynamics of CTX-M genes and supports strengthened surveillance to prevent the transmission of the antimicrobial-resistant genes to humans via the food chain. | Yoon, Sunghyun; Lee, Young Ju | Kyungpook Natl Univ, Coll Vet Med, 80 Daehak Ro, Daegu 41566, South Korea; Kyungpook Natl Univ, Zoo Noses Res Inst, 80 Daehak Ro, Daegu 41566, South Korea; USDA, Div Microbiol, Natl Ctr Toxicol Res, Jefferson, AR 72079 USA | ; Yoon, Sunghyun/AAL-4806-2021 | 57216037473; 56612134500 | youngju@knu.ac.kr; | JOURNAL OF VETERINARY SCIENCE | J VET SCI | 1229-845X | 1976-555X | 23 | 3 | SCIE | VETERINARY SCIENCES | 2022 | 1.8 | 34.4 | 3.26 | 2025-06-25 | 14 | 15 | Escherichia coli; Escherichia coli Infections; beta-lactamase CTX-M; E coli; beta-lactam resistance | ANTIBIOTIC-RESISTANCE; BETA-LACTAMASES; VIRULENCE; GENES; WORKERS; MEAT | beta-lactam resistance; beta-lactamase CTX-M; E coli; Escherichia coli; Escherichia coli Infections | Animals; Anti-Bacterial Agents; beta-Lactamases; Chickens; Escherichia coli; Escherichia coli Infections; Phylogeny; Plasmids; antiinfective agent; beta lactamase; Article; bacterial gene; bacterial strain; bacterium isolate; bacterium isolation; chicken; Escherichia coli infection; extended spectrum beta lactamase producing Escherichia coli; mobile genetic element; nonhuman; phylogeny; whole genome sequencing; animal; Escherichia coli; Escherichia coli infection; genetics; plasmid; veterinary medicine | English | 2022 | 2022-05 | 10.4142/jvs.21105 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Molecular characteristics of Escherichia coli from bulk tank milk in Korea | Background: Escherichia coli, which causes subclinical or clinical mastitis in cattle, is responsible for transmitting antimicrobial resistance via human consumption of raw milk or raw milk products. Objectives: The objective of this study was to investigate the molecular characteristics of 183 E. coli from bulk tank milk of five different dairy factories in Korea. Methods: The molecular characteristics of E. coli such as serogroup, virulence, antimicrobial resistance, and integron genes were detected using polymerase chain reaction and antimicrobial susceptibility were tested using the disk diffusion test. Results: In the distribution of phylogenetic groups, group D was the most prevalent (59.6%) and followed by group B1 (25.1%). The most predominant serogroup was O173 (15.3%), and a total of 46 different serotypes were detected. The virulence gene found most often was fimH (73.2%), and stx1, fimH, incC, fyuA, and iutA genes were significantly higher in isolates of phylogenetic group B1 compared to phylogenetic groups A, B2, and D (p < 0.05). Among 64 E. coli isolates that showed resistance to at least one antimicrobial, the highest resistance rate was observed for tetracyclines (37.5%). All 18 integron-positive E. coli carried the integron class I (int1) gene, and three different gene cassette arrangements, dfrA12+aadA2 (2 isolates), aac(6)'-Ib3+aac(6')-Ib-cr+aadA4 (2 isolates), and dfrA17+aadA5 (1 isolate) were detected. Conclusions: These data suggest that the E. coli from bulk tank milk can be an indicator for dissemination of antimicrobial resistance and virulence factors via cross-contamination. | Yoon, Sunghyun; Lee, Young Ju | Kyungpook Natl Univ, Coll Vet Med, Daegu 41566, South Korea; Kyungpook Natl Univ, Zoonoses Res Inst, Daegu 41566, South Korea; US FDA, Div Microbiol, Natl Ctr Toxicol Res, Jefferson, AR 72079 USA | Yoon, Sunghyun/AAL-4806-2021 | 57216037473; 56612134500 | youngju@knu.ac.kr; | JOURNAL OF VETERINARY SCIENCE | J VET SCI | 1229-845X | 1976-555X | 23 | 1 | SCIE | VETERINARY SCIENCES | 2022 | 1.8 | 34.4 | 1.95 | 2025-06-25 | 6 | 9 | Bulk tank milk; antimicrobial resistance; integron; virulence; Escherichia coli | CLASS 1 INTEGRONS; BETA-LACTAMASE; ANTIMICROBIAL SUSCEPTIBILITY; VIRULENCE FACTORS; BOVINE MASTITIS; RAW-MILK; RESISTANT; PREVALENCE; GENES; PHYLOGENY | antimicrobial resistance; Bulk tank milk; Escherichia coli; integron; virulence | Animals; Anti-Bacterial Agents; Cattle; Cattle Diseases; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Female; Integrons; Microbial Sensitivity Tests; Milk; Phylogeny; Republic of Korea; amoxicillin plus clavulanic acid; ampicillin; cefadroxil; cefalotin; cefazolin; cefepime; cefotaxime; cefoxitin; ceftazidime; cefuroxime; chloramphenicol; ciprofloxacin; colistin; cotrimoxazole; gentamicin; imipenem; nalidixic acid; tetracycline; antiinfective agent; antibiotic resistance; Article; bacterial virulence; bacterium isolate; bulk tank milk; class 1 integron; disk diffusion; Escherichia coli; fimH gene; fyuA gene; gene; gene cassette; incC gene; int1 gene; iutA gene; molecular genetics; nonhuman; phylogeny; polymerase chain reaction; raw milk; serotype; South Korea; stx1 gene; animal; bovine; cattle disease; classification; drug effect; Escherichia coli infection; female; genetics; integron; microbial sensitivity test; microbiology; milk; veterinary medicine | English | 2022 | 2022-01 | 10.4142/jvs.21084 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Safety Evaluation of Bacillus subtilis IDCC1101, Newly Isolated from Cheonggukjang, for Industrial Applications | The present study aimed to evaluate the safety of Bacillus subtilis (BS) IDCC1101, newly isolated from Cheonggukjang in Korea. Genome sequencing of BS IDCC1101 was performed to investigate the presence of secondary metabolites, virulence, antibiotic resistance, and mobile elements. Its phenotypic safety analyses included antibiotic susceptibility, enzyme activity, carbohydrate utilization, production of biogenic amines (BAs) and D-/L-lactate, hemolytic activity, and toxicities in HaCaT cells and rats. The genome of BS IDCC1101 consisted of 4,118,950 bp with 3077 functional genes. Among them, antimicrobial and antifungal secondary metabolites were found, such as fengycin, bacillibactin, and bacilysin. Antibiotic resistance and virulence genes did not exhibit transferability since they did not overlap with mobile elements in the genome. BS IDCC1101 was susceptible to almost all antibiotics suggested for assessment of BS's antibiotic susceptibility by EFSA guidelines, except for streptomycin. BS IDCC1101 showed the utilization of a wide range of 27 carbohydrates, as well as enzyme activities such as alkaline phosphatase, esterase, esterase lipase, naphthol-AS-BI-phosphohydrolase, alpha-galactosidase, beta-galactosidase, alpha-glucosidase, and beta-glucosidase activities. Additionally, BS IDCC1101 did not exhibit the production of D-/L-lactate and hemolytic activities. Its toxicity in HaCaT cells and rats was also not detected. Thus, these genotypic and phenotypic findings indicate that BS IDCC1101 can be safely used for industrial applications. | Kim, Su-Hyeon; Yehuala, Gashaw Assefa; Bang, Won Yeong; Yang, Jungwoo; Jung, Young Hoon; Park, Mi-Kyung | Kyungpook Natl Univ, Sch Food Sci & Biotechnol, Daegu 41566, South Korea; Kyungpook Natl Univ, Food & Bioind Res Inst, Daegu 41566, South Korea; Addis Ababa Sci & Technol Univ, Coll Biol & Chem Engn, Dept Food Engn, Addis Ababa 16417, Ethiopia; Ildong Biosci, Pyeongtaek Si 17957, South Korea | Park, Mi-Kyung/J-9643-2017; Jung, Young/F-1703-2013; Jung, Young Hoon/F-1703-2013 | 57217051011; 58029543700; 57208701768; 56076383700; 55550063700; 7404491155 | parkmik@knu.ac.kr; | MICROORGANISMS | MICROORGANISMS | 2076-2607 | 10 | 12 | SCIE | MICROBIOLOGY | 2022 | 4.5 | 34.4 | 1.9 | 2025-06-25 | 16 | 19 | Bacillus subtilis IDCC1101; safety evaluation; industrial application; probiotics; genomic analysis | BIOGENIC-AMINES; STRAINS; FOOD; PATHOGENESIS; MECHANISMS; CAPSULE | Bacillus subtilis IDCC1101; genomic analysis; industrial application; probiotics; safety evaluation | English | 2022 | 2022-12 | 10.3390/microorganisms10122494 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Serological evidence of Anaplasma spp., Borrelia burgdorferi and Ehrlichia canis in dogs from the Republic of Korea by rapid diagnostic test kits | Background: Emergent and re-emergent canine tick-borne infections are attracting increasing attention worldwide. The rise in pet ownership and the close relationship between dogs and their owners are the most concerning factors because dogs may act as competent reservoirs for human tick-transmitted infectious agents. Objectives: This study contributes to the epidemiological surveillance of canine tick transmitted infections with zoonotic risk in the Republic of Korea (ROK) by investigating the seroprevalence of the pathogens, Anaplasma spp., Borrelia burgdorferi, and Ehrlichia canis. Methods: Four hundred and thirty whole blood samples from domestic dogs were collected in seven metropolitan cities and nine provinces in the ROK and tested using SensPERT Ab test kits (VetAll Laboratories (R)) to detect seroreactive animals. Results: The seroprevalence rates identified were 9.8% (42/430) for Anaplasma spp., 2.8% (12/430) for B. burgdorferi, and 1.4% (6/430) for E. canis. The risk factors evaluated in this study that could be associated with the development of a humoral immune response, such as sex, age, and history of tick exposure, were similar. There was only one exception for dogs seroreactive to Anaplasma spp., where the risk factor "tick exposure" was statistically significant (p = 0.047). Conclusions: This serological survey exhibited the widespread presence of Anaplasma spp., B. burgdorferi, and E. canis throughout the ROK. Hence, dogs may play a key role as the sentinel animals of multiple zoonotic infectious agents in the country. | Miranda, Evelyn Alejandra; Han, Sun-Woo; Rim, Ji-Min; Cho, Yoon-Kyoung; Choi, Kyoung-Seong; Chae, Joon-Seok | Seoul Natl Univ, Res Inst Vet Sci, BK21 FOUR Future Vet Med Leading Educ & Res Ctr, Lab Vet Internal Med, 1 Gwanak Ro, Seoul 08826, South Korea; Seoul Natl Univ, Coll Vet Med, 1 Gwanak Ro, Seoul 08826, South Korea; Kyungpook Natl Univ, Coll Ecol & Environm Sci, Sangju 37224, South Korea | 57221444863; 57216636732; 57226753955; 57201634305; 7403949556; 7102478039 | jschae@snu.ac.kr; | JOURNAL OF VETERINARY SCIENCE | J VET SCI | 1229-845X | 1976-555X | 23 | 2 | SCIE | VETERINARY SCIENCES | 2022 | 1.8 | 34.4 | 1.09 | 2025-06-25 | 4 | 5 | Anaplasma; Borrelia burgdorferi; Ehrlichia canis; seroprevalence; dog | TICK-BORNE INFECTIONS; THROMBOCYTOPENIA SYNDROME VIRUS; GRANULOCYTIC ANAPLASMOSIS; SHELTER DOGS; SEVERE FEVER; PHAGOCYTOPHILUM; PREVALENCE; CHAFFEENSIS; DISEASES | Anaplasma; Borrelia burgdorferi; dog; Ehrlichia canis; seroprevalence | Anaplasma; Anaplasmosis; Animals; Antibodies, Bacterial; Borrelia burgdorferi; Dog Diseases; Dogs; Ehrlichia; Ehrlichia canis; Ehrlichiosis; Lyme Disease; Reagent Kits, Diagnostic; Seroepidemiologic Studies; bacterium antibody; aging; Anaplasma; anaplasmosis; Article; blood sampling; Borrelia burgdorferi; canine ehrlichiosis; disease transmission; dog; Ehrlichia canis; epidemiological surveillance; female; humoral immunity; infection risk; Lyme disease; male; medical history; nonhuman; serology; seroprevalence; sex ratio; South Korea; urban area; anaplasmosis; animal; Borrelia burgdorferi; diagnostic kit; dog disease; Ehrlichia; ehrlichiosis; Lyme disease; seroepidemiology; veterinary medicine | English | 2022 | 2022-03 | 10.4142/jvs.21215 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | The effect of serotonin and oxytocin on equine docility and friendliness to humans | Neurotransmitters play important roles in animal behaviors. Serotonin (5-HT) and oxytocin (OXT) are well-known neurotransmitters affecting animals' social behavior. Recently, we demonstrated the effect of OXT on horse docility and friendliness to humans. However, the correlation of 5-HT and OXT with horse docility and friendliness to humans remains to be elucidated. This study aims to (1) evaluate the effect of breed, age, and sex on 5-HT and OXT concentrations in horses, (2) examine the correlation between 5-HT and OXT, and (3) to test the effect of 5-HT on the docility and friendliness toward humans. Blood samples were collected from 29 horses at the Horse Industry Complex Center of Jeonju Kijeon College. The horse breeds comprised Thoroughbreds, ponies, Warmbloods, and Haflingers. There were 20 mares and 9 geldings. Based on age, the horses were grouped into postpubertal, adult, and aged horses. The plasma concentration of 5-HT or OXT was measured by ELISA. The temperament of each horse was evaluated by 3 professors who were familiar with all the horses. The mixed model through least significant difference posthoc analysis was conducted to analyze the effect of fixed factors (breed, age, and sex) and interaction factor (breed x age x sex) on random effect (neurotransmitter levels). The Student T-test was performed to analyze the effect of sex (geldings and mares) on 5-HT or OXT concentrations. The linear regression analysis was performed to test the correlation between (1) the plasma concentration of 5-HT and OXT and (2) the plasma concentration of 5-HT or OXT with the score of equine docility and friendliness toward humans. The 5-HT concentration of Warmbloods and OXT concentration of Warmbloods and Thoroughbreds were significantly higher than those of ponies. The concentration of OXT in the aged horse was considerably higher than that of postpubertal horses. Interestingly, there is a positive correlation between the concentrations of plasma 5-HT and OXT. Also, 5-HT showed a positive correlation with horses' docility and friendliness toward humans. In conclusion, the plasma concentration of 5-HT in combination with OXT can be used as a parameter to identify a horse's docility and friendliness to humans. (C) 2022 Elsevier Inc. All rights reserved. | Kim, Junyoung; Yoon, Minjung | Kyungpook Natl Univ, Dept Anim Sci & Biotechnol, Sangju 37224, South Korea | 57218494918; 22137296500 | mjyoonemail@gmail.com; | JOURNAL OF VETERINARY BEHAVIOR-CLINICAL APPLICATIONS AND RESEARCH | J VET BEHAV | 1558-7878 | 1878-7517 | 50 | SCIE | BEHAVIORAL SCIENCES;VETERINARY SCIENCES | 2022 | 1.8 | 34.4 | 1.09 | 2025-06-25 | 6 | 5 | Horses; Serotonin; Oxytocin; Docility; Friendliness | BRAIN-SEROTONIN; RELEASE; AGE; VASOPRESSIN; NEURONS; TEMPERAMENT | Docility; Friendliness; Horses; Oxytocin; Serotonin | neurotransmitter; oxytocin; serotonin; adult; animal behavior; Article; blood sampling; breeding; concentration (parameter); controlled study; enzyme linked immunosorbent assay; Equus; female; gelding; groups by age; haflinger; horse breed; human; human-animal interaction; male; mare; nonhuman; oxytocin blood level; ponies; serotonin blood level; sex difference; thoroughbred; warmblood | English | 2022 | 2022-04 | 10.1016/j.jveb.2022.01.004 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Review | Updates on Group B Streptococcus Infection in the Field of Obstetrics and Gynecology | Group B Streptococcus (GBS, Streptococcus agalactiae) is a Gram-positive bacterium that is commonly found in the gastrointestinal and urogenital tracts. However, its colonization during pregnancy is an important cause of maternal and neonatal morbidity and mortality worldwide. Herein, we specifically looked at GBS in relation to the field of Obstetrics (OB) along with the field of Gynecology (GY). In this review, based on the clinical significance of GBS in the field of OBGY, topics of how GBS is being detected, treated, and should be prevented are addressed. | Choi, Yeseul; Han, Hyung-Soo; Chong, Gun Oh; Le, Tan Minh; Nguyen, Hong Duc Thi; Lee, Olive E. M.; Lee, Donghyeon; Seong, Won Joon; Seo, Incheol; Cha, Hyun-Hwa | Kyungpook Natl Univ, Sch Med, Dept Biomed Sci, Grad Program, Daegu 41944, South Korea; Kyungpook Natl Univ, Sch Med, BK21 Four Program, Daegu 41944, South Korea; Kyungpook Natl Univ, Sch Med, Dept Physiol, Daegu 41944, South Korea; Kyungpook Natl Univ, Clin Omics Inst, Daegu 41405, South Korea; Kyungpook Natl Univ, Dept Obstet & Gynecol, Chilgok Hosp, Daegu 41404, South Korea; Kyungpook Natl Univ, Sch Med, Dept Immunol, Daegu 41944, South Korea | ; Le, Tan/ITT-2150-2023 | 57226123444; 7401969388; 23099068000; 57870749600; 57870555300; 58029901300; 57870503500; 26656946000; 56022683900; 37033517800 | iseo@knu.ac.kr;chh9861@knu.ac.kr; | MICROORGANISMS | MICROORGANISMS | 2076-2607 | 10 | 12 | SCIE | MICROBIOLOGY | 2022 | 4.5 | 34.4 | 0.44 | 2025-06-25 | 13 | 11 | Group B Streptococcus; obstetrics; gynecology; early-onset disease; late-onset disease; vaginosis; detection; intrapartum antibiotic prophylaxis; GBS vaccine; microbial therapy | CERVICAL INTRAEPITHELIAL NEOPLASIA; LOW-BIRTH-WEIGHT; BACTERIAL VAGINOSIS; VAGINAL MICROBIOME; PRETERM DELIVERY; PREGNANT-WOMEN; MATERNAL COLONIZATION; AEROBIC VAGINITIS; OVARIAN-CANCER; RISK-FACTOR | detection; early-onset disease; GBS vaccine; Group B Streptococcus; gynecology; intrapartum antibiotic prophylaxis; late-onset disease; microbial therapy; obstetrics; vaginosis | English | 2022 | 2022-12 | 10.3390/microorganisms10122398 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Review | Vivax Malaria and the Potential Role of the Subtelomeric Multigene vir Superfamily | Vivax malaria, caused by Plasmodium vivax, remains a public health concern in Central and Southeast Asia and South America, with more than two billion people at risk of infection. Compared to Plasmodium falciparum, P. vivax is considered a benign infection. However, in recent decades, incidences of severe vivax malaria have been confirmed. The P. falciparum erythrocyte membrane protein 1 family encoded by var genes is known as a mediator of severe falciparum malaria by cytoadherence property. Correspondingly, the vir multigene superfamily has been identified as the largest multigene family in P. vivax and is implicated in cytoadherence to endothelial cells and immune response activation. In this review, the functions of vir genes are reviewed in the context of their potential roles in severe vivax malaria. | Goo, Youn-Kyoung | Kyungpook Natl Univ, Sch Med, Dept Parasitol & Trop Med, Daegu 41944, South Korea | 22937863200 | kuku1819@knu.ac.kr; | MICROORGANISMS | MICROORGANISMS | 2076-2607 | 10 | 6 | SCIE | MICROBIOLOGY | 2022 | 4.5 | 34.4 | 0.12 | 2025-06-25 | 4 | 3 | Plasmodium vivax; vir gene; severe vivax malaria; cytoadherence; immune response | PLASMODIUM-VIVAX; GENES; FALCIPARUM; PROTEINS; ANTIGENS; CELLS; AREA | cytoadherence; immune response; Plasmodium vivax; severe vivax malaria; vir gene | English | 2022 | 2022-06 | 10.3390/microorganisms10061083 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Assessment of nitrogen interaction with temperature on the growth and toxin production of mat-forming toxin-producing Anagnostidinema carotinosum | Aims Global warming and eutrophication contribute to the severity of cyanobacteria blooms. However, it is unclear how these factors influence the growth and toxin production of Anagnostidinema carotinosum. Methods and Results Based on morphological and molecular analysis, this is the first time A. carotinosum was identified in South Korea. The interactive effect of temperature (25, 30 or 34 degrees C) and nitrogen (2.5, 3.5 or 4.5 mg NO3-N l(-1)) on A. carotinosum growth and toxin production was studied. Increasing nitrogen limitation reflects reduced growth and chlorophyll-a content at all temperatures. However, the growth was effective under nitrogen limitation when temperatures exceeded 25 degrees C. The maximum growth was found at 30 degrees C, followed by 34 degrees C under higher nitrate levels (3.5 and 4.5 mg l(-1)). In addition, the cell microcystin and anatoxin-a quota increased significantly at 25 degrees C with increasing nitrate limitation, decreasing considerably at 30 degrees C in the same nitrate gradient. Conclusion These results suggested temperatures stimulate A. carotinosum growth at 30 and 34 degrees C and cellular toxin quota at 25 and 34 degrees C with increasing NO3-N levels. Significance and Impact of the Study These findings imply that limiting nitrogen input alone can effectively reduce biomass; however, controlling A. carotinosum and its toxins at higher temperatures under nitrate limitation is necessary for water quality. | Anam, Giridhar Babu; Muthusamy, Govarthanan; Ahn, Young-Ho | Yeungnam Univ, Dept Civil Engn, Gyongsan 38541, Gyeongbuk, South Korea; Kyungpook Natl Univ, Dept Environm Engn, Deagu, South Korea; Saveetha Dent Coll & Hosp, Saveetha Inst Med & Tech Sci, Dept Biomat, Chennai, Tamil Nadu, India | Govarthanan, Muthusamy/C-1491-2014; Anam, Giridhar Babu/P-4009-2016; Muthusamy, Govarthanan/C-1491-2014; Anam, Giridhar/P-4009-2016 | 57194436957; 54881927600; 24586951200 | yhahn@ynu.ac.kr; | JOURNAL OF APPLIED MICROBIOLOGY | J APPL MICROBIOL | 1364-5072 | 1365-2672 | 133 | 5 | SCIE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY;MICROBIOLOGY | 2022 | 4 | 34.5 | 0.3 | 2025-06-25 | 2 | 3 | Anagnostidinema; cyanobacteria; cyanotoxins; nitrogen; temperature | CYANOBACTERIUM MICROCYSTIS-AERUGINOSA; CYLINDROSPERMOPSIS-RACIBORSKII; NAKDONG RIVER; GEITLERINEMA; EUTROPHICATION; PHOTOSYNTHESIS; IDENTIFICATION; STRESS; SYSTEM; BLOOMS | Anagnostidinema; cyanobacteria; cyanotoxins; nitrogen; temperature | Chlorophyll; Cyanobacteria; Microcystins; Nitrates; Nitrogen; Temperature; South Korea; Eutrophication; Global warming; Nitrates; Toxic materials; Water quality; anatoxin a; chlorophyll a; cycloheximide; microcystin; nitrate; nitrogen; superoxide dismutase; toxin; chlorophyll; microcystin; nitric acid derivative; nitrogen; Anagnostidinema; Cyanobacteria blooms; Cyanobacterium; Cyanotoxins; Mat forming; Molecular analysis; Morphological analysis; Nitrogen limitation; South Korea; Toxin production; biomass; cell; cyanobacterium; growth response; nitrogen; toxin; algal growth; Anagnostidinema carotinosum; Article; controlled study; cyanobacterium; enzyme activity; growth period; incubation time; nitrogen concentration; nonhuman; nucleotide sequence; phylogeny; South Korea; temperature; water quality; temperature; Nitrogen | English | 2022 | 2022-11 | 10.1111/jam.15784 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Improved Tunneling Property of p plus Si Nanomembrane/n plus GaAs Heterostructures through Ultraviolet/Ozone Interface Treatment | Here, heterostructures composed of p+Si nanomembranes (NM)/n+GaAs were fabricated by ultraviolet/ozone (UV/O-3, UVO) treatment, and their tunneling properties were investigated. The hydrogen (H)-terminated Si NM was bonded to the oxygen (O)-terminated GaAs substrate, leading to Si/GaAs tunnel junctions (TJs). The atomic-scale features of the H-O-terminated Si/GaAs TJ were analyzed and compared to those of Si/GaAs heterojunctions with no UVO treatment. The electrical characteristics demonstrated the emergence of negative differential resistance, with an average peak-to-valley current ratio of 3.49, which was examined based on the band-to-band tunneling and thermionic emission theories. | Kim, Kwangeun; Jang, Jaewon | Korea Aerosp Univ, Sch Elect & Informat Engn, Goyang 10540, South Korea; Kyungpook Natl Univ, Sch Elect Engn, Daegu 41566, South Korea | 36004977500; 57194107504 | kke@kau.ac.kr;j1jang@knu.ac.kr; | INORGANICS | INORGANICS | 2304-6740 | 10 | 12 | SCIE | CHEMISTRY, INORGANIC & NUCLEAR | 2022 | 2.9 | 34.5 | 0.1 | 2025-06-25 | 1 | 1 | inorganic semiconductor; compound semiconductor; nanomembrane; heterostructure; ultraviolet; ozone treatment | ESAKI DIODES | compound semiconductor; heterostructure; inorganic semiconductor; nanomembrane; ultraviolet/ozone treatment | English | 2022 | 2022-12 | 10.3390/inorganics10120228 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Review | Role of the JNK Pathway in Bladder Cancer | Bladder cancer, one of the most frequently diagnosed cancers worldwide, is associated with high morbidity and mortality and a poor prognosis. The bladder cancer types include 1) non-muscle invasive bladder cancer (NMIBC) and 2) muscle invasive bladder cancer (MIBC). Metastases and chemoresistance in MIBC patients are the leading causes of the high death rate. c-Jun N-terminal kinase (JNK) is an important factor for the undifferentiated state of cancer cells. JNK belongs to the mitogen-activated protein kinases (MAPKs) family; it is activated by various extracellular stimuli, such as stress, radiation, and growth factors and mediates diverse cellular functions, such as apoptosis, autophagy, proliferation, invasion, and migration by mediating AKT (Ak strain transforming), ATG (Autophagy related), mTOR (Mammalian target of rapamycin), and caspases 3, 8, and 9. This review describes the JNK-related functions, mechanisms, and signaling in bladder cancer. | Lee, Eun Hye; Kim, Hyun Tae; Chun, So Young; Chung, Jae-Wook; Choi, Seock Hwan; Lee, Jun Nyung; Kim, Bum Soo; Yoo, Eun Sang; Kwon, Tae Gyun; Kim, Tae-Hwan; Ha, Yun-Sok | Kyungpook Natl Univ, Joint Inst Regenerat Med, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Urol, Daegu, South Korea; Kyungpook Natl Univ Hosp, BioMed Res Inst, Daegu, South Korea | Kim, Soo-Yeon/ADR-9663-2022; Lee, Yun-Soo/AAA-7364-2022; Kim, Young-Bo/AAR-8052-2021; Kim, Tae/B-9921-2013 | 57189661699; 55739531300; 8688166900; 35204798500; 9742645500; 16301364600; 57202817150; 7006609239; 15073765400; 57797823600; 35487226400 | doctork@knu.ac.kr;yunsokha@gmail.com; | ONCOTARGETS AND THERAPY | ONCOTARGETS THER | 1178-6930 | 15 | SCIE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY;ONCOLOGY | 2022 | 4 | 34.5 | 0.69 | 2025-06-25 | 10 | 13 | bladder cancer; JNK; proliferation; apoptosis; metastasis; chemoresistance; autophagy | N-TERMINAL KINASE; SIGNAL-TRANSDUCTION; APOPTOSIS; AUTOPHAGY; INVASION; CELLS; ACTIVATION; METASTASIS; EXPRESSION; CARCINOMA | apoptosis; autophagy; bladder cancer; chemoresistance; JNK; metastasis; proliferation | cisplatin; mitomycin; stress activated protein kinase; antigenic escape; apoptosis; autophagy (cellular); bladder cancer; carcinogenesis; cell metabolism; cell proliferation; cell survival; drug resistance; enzyme mechanism; human; JNK signaling; lipid metabolism; metastasis; Review; tumor cell | English | 2022 | 2022 | 10.2147/ott.s374908 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Sequential Afatinib and Osimertinib in Asian Patients with EGFR Mutation-Positive Non-Small Cell Lung Cancer and Acquired T790M: Combined Analysis of Two Global Non-Interventional Studies | Objective: Two recent non-interventional trials, GioTag and UpSwinG, demonstrated encouraging time-to-treatment failure (TTF) and overall survival (OS) in patients with epidermal growth factor receptor (EGFR) mutation-positive non-small cell lung cancer (NSCLC) (Del19 or L858R) who received sequential afatinib/osimertinib, especially in Asians. Here, we have undertaken a combined analysis of Asian patients from both studies. Materials and Methods: Existing medical/electronic records were identified for consecutive EGFR-tyrosine kinase inhibitor (TKI)-naive patients who received first-line afatinib/second-line osimertinib in "real-world" practice (all T790M-positive). Patients with active brain metastases were excluded. The primary objective was TTF. OS was a key secondary objective. Results: One hundred and sixty-eight patients were analyzed. Most patients were recruited from South Korea or Japan (52/21%). At the start of afatinib, median age (range) was 61.5 years (35-88), 58% were female, Eastern Cooperative Oncology Group Performance Status (ECOG PS) (0/1/>= 2) was 29/62/9%, 17% had brain metastases, and EGFR mutation status (Del19/L858R) was 65/35%. At the start of osimertinib, ECOG PS (0/1/>= 2) was 22/61/17% and 14% had brain metastases. Median TTF and OS were 30.0 months (95% CI: 24.5-32.5) and 45.2 months (95% CI: 41.7-71.1), respectively. Median OS was 63.5 months in patients with a Del19 mutation. Median OS in patients with brain metastases or ECOG PS >= 2 was 26.4 and 33.1 months, respectively. Conclusion: Sequential afatinib/osimertinib showed encouraging activity in Asian patients with EGFR mutation-positive NSCLC and T790M-mediated acquired resistance, especially those with Del19-positive disease. Activity was observed across "real-world" patients including those with poor ECOG PS and/or brain metastases. ECOG PS and incidence of brain metastases remained stable prior to, and after, afatinib. | Miura, Satoru; Jung, Hyun Ae; Lee, Shin Yup; Lee, Seung Hyeun; Lee, Min Ki; Lee, Yong Chul; Hochmair, Maximilian J.; Yang, Cheng-Ta; Marten, Angela; Yang, James Chih-Hsin; Popat, Sanjay | Niigata Canc Ctr Hosp, Dept Internal Med, Niigata, Japan; Sungkyunkwan Univ, Samsung Med Ctr, Dept Med, Div Hematol Oncol,Sch Med, Seoul, South Korea; Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu, South Korea; Kyung Hee Univ, Sch Med, Dept Internal Med, Div Pulm & Crit Care Med,Med Ctr, Seoul, South Korea; Pusan Natl Univ, Dept Internal Med, Sch Med, Busan, South Korea; Jeonbuk Natl Univ, Res Ctr Pulm Disorders, Dept Internal Med, Med Sch, Jeonju, South Korea; Karl Landsteiner Inst Lung Res & Pulm Oncol, Dept Resp & Crit Care Med, Vienna, Austria; Chang Gung Mem Hosp, Dept Thorac Med, Taoyuan, Taiwan; Ingelheim Rhein, Boehringer Ingelheim Int GmbH, Ingelheim, Germany; Natl Taiwan Univ, Canc Ctr, Dept Med Oncol, Taipei, Taiwan; Natl Taiwan Univ Hosp, Dept Oncol, Taipei, Taiwan; Royal Marsden Natl Hlth Serv Fdn Trust, Lung Unit, London SW3 6JJ, England; Inst Canc Res, London, England | ; Yang, James/W-1587-2019; Lee, Seung Hyeun/P-5566-2018; Popat, Sanjay/AAO-1634-2021 | 22934797200; 35272249400; 49863712700; 57208400366; 16433227400; 57191489788; 14032862400; 8201458000; 7003348582; 56949914100; 6701774598 | sanjay.popat@rmh.nhs.uk; | ONCOTARGETS AND THERAPY | ONCOTARGETS THER | 1178-6930 | 15 | SCIE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY;ONCOLOGY | 2022 | 4 | 34.5 | 1.01 | 2025-06-25 | 8 | 8 | EGFR; afatinib; osimertinib; sequential; T790M | 1ST-LINE TREATMENT; OPEN-LABEL; GEFITINIB; RESISTANCE; THERAPY; NSCLC | afatinib; EGFR; osimertinib; sequential; T790M | afatinib; osimertinib; adult; aged; Article; Asian; brain metastasis; clinical effectiveness; drug effect; drug efficacy; drug response; ECOG Performance Status; EGFR gene; female; gene; gene mutation; genetic association; human; Japan; major clinical study; male; non small cell lung cancer; South Korea; survival rate; treatment failure; treatment outcome | English | 2022 | 2022 | 10.2147/ott.s362535 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Review | The role of plant-associated rhizobacteria in plant growth, biocontrol and abiotic stress management | The rhizosphere is the region around the plant roots where maximum microbial activities occur. In the rhizosphere, microorganisms' beneficial and harmful activities affect plant growth and development. The mutualistic rhizospheric bacteria which improve plant growth and health are known as plant growth-promoting rhizobacteria (PGPR). They are very important due to their ability to help the plant in diverse ways. PGPR such as Pseudomonas, Bacillus, Azospirillum, Azotobacter, Arthrobacter, Achromobacter, Micrococcus, Enterobacter, Rhizobium, Agrobacterium, Pantoea and Serratia are now very well known. Rhizomicrobiome plays critical roles in nutrient acquisition and assimilation, improved soil texture, secreting and modulating extracellular molecules such as hormones, secondary metabolites, antibiotics and various signal compounds, all leading to the enhancement of plant growth and development. The microbes and compounds they secrete constitute valuable biostimulants and play pivotal roles in modulating plant stress responses. In this review, we highlight the rhizobacteria diversity and cutting-edge findings focusing on the role of a PGPR in plant growth and development. We also discussed the role of PGPR in resisting the adverse effects arising from various abiotic (drought, salinity, heat, heavy metals) stresses. | Bhat, Basharat Ahmad; Tariq, Lubna; Nissar, Showkat; Islam, Sheikh Tajamul; Ul Islam, Shahid; Mangral, Zahid; Ilyas, Noshin; Sayyed, Riyaz Z.; Muthusamy, Govarthanan; Kim, Woong; Dar, Tanvir Ul Hasan | Univ Kashmir, Sch Biol Sci, Dept Bioresources, Srinagar, India; BGSB Univ, Sch Biosci & Biotechnol, Dept Biotechnol, Rajouri 185234, India; Univ Kashmir, Sch Biol Sci, Dept Bot, Srinagar, India; PMAS Arid Agr Univ, Dept Bot, Rawalpindi, Pakistan; Asian PGPR Soc, Auburn Ventures, Auburn, AL 36830 USA; Kyungpook Natl Univ, Dept Environm Engn, Daegu, South Korea | ; Govarthanan, Muthusamy/C-1491-2014; Tariq, Lubna/AAC-6294-2022; Muthusamy, Govarthanan/C-1491-2014; Ilyas, Noshin/G-2803-2018; Sayyed, Riyaz/Q-4313-2016 | 59545147000; 57222631326; 57742255400; 37101640300; 57222639989; 57222639747; 26023278300; 55403640000; 54881927600; 55581636400; 26433325100 | sayyedrz@gmail.com;tanvirulhasan@gmail.com; | JOURNAL OF APPLIED MICROBIOLOGY | J APPL MICROBIOL | 1364-5072 | 1365-2672 | 133 | 5 | SCIE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY;MICROBIOLOGY | 2022 | 4 | 34.5 | 3.47 | 2025-06-25 | 92 | 96 | abiotic stress; inorganic fertilizers; PGPR; rhizosphere; sustainable agriculture | PROMOTING RHIZOBACTERIA; NITROGEN-FIXATION; DROUGHT STRESS; SUSTAINABLE AGRICULTURE; FLUORESCENT PSEUDOMONAS; RHIZOSPHERE BACTERIA; BACILLUS-SUBTILIS; SALINITY-STRESS; SPHINGOMONAS SP; IONIC BALANCE | abiotic stress; inorganic fertilizers; PGPR; rhizosphere; sustainable agriculture | Anti-Bacterial Agents; Hormones; Metals, Heavy; Pantoea; Plant Development; Plant Roots; Rhizosphere; Soil; Soil Microbiology; Stress, Physiological; Bacteria; Bacteriology; Fertilizers; Heavy metals; Metabolites; Soils; antibiotic agent; fertilizer; heavy metal; hormone; antiinfective agent; heavy metal; Abiotic stress; Growth and development; Growth stress; Inorganic fertilizers; Plant development; Plant growth; Plant growth-promoting rhizobacteria; Rhizobacteria; Rhizosphere; Sustainable agriculture; alternative agriculture; antibiotics; fertilizer application; growth response; hormone; microbial activity; rhizobacterium; rhizosphere; secondary metabolite; secretion; soil texture; abiotic stress; Achromobacter; Agrobacterium; Arthrobacter; Azospirillum; Azotobacter; Bacillus; bacterial growth; biological control agent; biological pest control; drought; drought stress; Enterobacter; heat; heat tolerance; microbial activity; Micrococcus; microorganism; nonhuman; nutrient; osmotic stress; Pantoea; plant development; plant growth; plant root; Pseudomonas; Review; Rhizobium; rhizosphere bacterium; salinity; salt stress; Serratia; Sesbania; soil texture; Streptomyces; sustainable agriculture; microbiology; Pantoea; physiological stress; rhizosphere; soil; Textures | English | 2022 | 2022-11 | 10.1111/jam.15796 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Knockdown of Maged1 inhibits cell cycle progression and causes cell death in mouse embryonic stem cells | Mouse embryonic stem cells (mESCs) are characterized by self-renewal and pluripotency and can undergo differentiation into the three germ layers (ectoderm, mesoderm, and endoderm). Melanoma-associated antigen D1 (Maged1), which is expressed in all developing and adult tissues, modulates tissue regeneration and development. In the present study, we examined the expression and function of Maged1 in mESCs. Maged1 protein and mRNA expression increased during mESC differentiation. The pluripotency of mESCs was significantly reduced through extracellular signal-regulated kinase 1/2 phosphorylation upon knockdown of Maged1, and through G(1) cell cycle arrest during cell division, resulting in significantly reduced mESC proliferation. Moreover, the diameter of the embryoid bodies was significantly reduced, accompanied by increased levels of ectodermal differentiation markers and decreased levels of mesodermal and endodermal differentiation markers. Maged1-knockdown mESC lines showed significantly reduced teratoma volumes and inhibition of teratoma formation in nude mice. Additionally, we observed increased ectodermal markers but decreased mesodermal and endodermal markers in teratoma tissues. These findings show that Maged1 affects mESC pluripotency, proliferation, cell cycle, and differentiation, thereby contributing to our understanding of the basic molecular biological mechanisms and potential roles of Maged1 as a regulator of various mESC properties. | Park, Song; Kwon, Wookbong; Kim, Hee-Yeon; Ji, Young Rae; Kim, Daehwan; Kim, Wansoo; Han, Jee Eun; Cho, Gil-Jae; Yun, Sungho; Kim, Myoung Ok; Ryoo, Zae Young; Han, Se-Hyeon; Park, Jin-Kyu; Choi, Seong-Kyoon | DGIST, Div Biotechnol, Daegu, South Korea; DGIST, Core Prot Resources Ctr, Daegu, South Korea; DGIST, Dept Brain Sci, Daegu, South Korea; Kyungpook Natl Univ, BK21 Four KNU Creat Biores Grp, Sch Life Sci, Daegu, South Korea; Kyungpook Natl Univ, Coll Vet Med, Daegu 41566, South Korea; Hanyang Univ, Sch Media Commun, Wangsimni Ro 222, Seoul, South Korea; SBS Seoul Broadcasting Syst, Dept News Team, Mokdongseo Ro 161, Seoul, South Korea; Kyungpook Natl Univ, Dept Anim Sci & Biotechnol, ITRD, Sangju 37224, South Korea | Ji, Youngrae/AAK-9724-2021; RYOO, ZAEYOUNG/AAQ-1573-2020 | 57139047900; 57139843600; 58368914700; 36672985800; 57212363780; 57352897900; 57214671240; 7201438083; 57201366734; 8934745900; 16937104900; 57210915063; 35213723500; 55505432500 | jinkyu820@knu.ac.kr;cskbest@dgist.ac.kr; | DIFFERENTIATION | DIFFERENTIATION | 0301-4681 | 1432-0436 | 125 | SCIE | CELL BIOLOGY;DEVELOPMENTAL BIOLOGY | 2022 | 2.9 | 34.6 | 0.29 | 2025-06-25 | 3 | 3 | Maged1; Pluripotency; Cell cycle; Differentiation; Erk1/2 | IN-VITRO DIFFERENTIATION; SELF-RENEWAL; PROTEIN; NRAGE; ACTIVATION; APOPTOSIS; STAT3; PROLIFERATION; EXPRESSION; REGULATOR | Cell cycle; Differentiation; Erk1/2; Maged1; Pluripotency | Animals; Antigens, Differentiation; Cell Cycle; Cell Death; Cell Differentiation; Cell Division; Mice; Mice, Nude; Mouse Embryonic Stem Cells; Neoplasm Proteins; Teratoma; mitogen activated protein kinase 1; mitogen activated protein kinase 3; differentiation antigen; Maged1 protein, mouse; tumor protein; animal cell; apoptosis; Article; cell death; cell division; cell proliferation; controlled study; embryoid body; embryonic stem cell; G1 phase cell cycle checkpoint; gene; gene expression; gene knockdown; in vitro study; in vivo study; Maged1 gene; male; mouse; nonhuman; protein phosphorylation; real time polymerase chain reaction; Western blotting; animal; cell cycle; cell death; cell differentiation; genetics; metabolism; mouse embryonic stem cell; nude mouse; teratoma | English | 2022 | 2022 (MAY-JUN) | 10.1016/j.diff.2022.03.003 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Chromosome and ploidy analysis of winter hardy Hibiscus species by FISH and flow cytometry | Determination of nuclear DNA content, genome size, and ploidy level and, information on cytogenetic characteristics are all prerequisite of modern plant breeding. However, identification of individual chromosomes of Hibiscus species is extremely difficult due to high number, small size and similar shape of mitotic chromosomes. The goal of the study was to ascertain the chromosome number, karyomorphology, distribution of 5S and 18S rDNA signals, chromosome length, and centromere positions as well as the ploidy level, genome sizes, 2C - DNA content of winter-hardy Hibiscus (H. syriacus 'Saejamyung', H. sinosyriacus 'Seobong', H. moscheutos 'Luna Red' and, H. paramutabilis). 5S rDNA and 18S rDNA signals were detected by fluorescence in situ hybridization (FISH). According to the FISH results, there are two 5S rDNA signals (green) in H. syriacus, H. sinosyriacus, and H. moscheutos, and four 5S rDNA signals in H. paramutabilis. The range in length of somatic chromosomes in H. syriacus, H. sinosyriacus, H. moscheutos, and H. paramutabilis is 2.66-7.06, 3.18-7.31, 2.91-5.23, and 4.75-7.60, respectively. The 2C - DNA content of H. syriacus, H. sinosyriacus, and H. paramutabilis are very similar, the amount was 4.06, 4.11, and 4.18 pg, respectively whereas, H. moscheutos has nearly half and that amount was 2.06 pg. These findings will contribute to the detailed cytogenetic assessment of Hibiscus and thus benefit plant breeding in this genus. | Deepo, Deen Mohammad; Mazharul, Islam Md; Hwang, Yoon-Jung; Kim, Hong-Yul; Kim, Chang Kil; Lim, Ki-Byung | Kyungpook Natl Univ, Dept Hort Sci, Daegu 41566, South Korea; Sahmyook Univ, Dept Life Sci, Seoul 01795, South Korea; Kyungpook Natl Univ, Inst Agr Sci & Technol, Daegu 41566, South Korea | Islam, Md Mazharul/AFS-6460-2022; park, jun yeon/GPX-5293-2022; Islam, Mazharul/AFS-6460-2022 | 57216909682; 57219091958; 50061210800; 56941037200; 7409880701; 7403175915 | kblim@knu.ac.kr; | EUPHYTICA | EUPHYTICA | 0014-2336 | 1573-5060 | 218 | 6 | SCIE | AGRONOMY;HORTICULTURE;PLANT SCIENCES | 2022 | 1.9 | 34.7 | 0.65 | 2025-06-25 | 5 | 6 | Hibiscus; Cytogenetics; Fluorescence in situ hybridization; 5S rDNA; 18S rDNA | IN-SITU HYBRIDIZATION; KARYOTYPE ANALYSIS; GENOME SIZE; HYBRIDS; EVOLUTION; SYRIACUS | 18S rDNA; 5S rDNA; Cytogenetics; Fluorescence in situ hybridization; Hibiscus | English | 2022 | 2022-06 | 10.1007/s10681-022-02977-2 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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