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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Article | Investigating the Functional Role of the Cysteine Residue in Dehydrin from the Arctic Mouse-Ear Chickweed Cerastium arcticum | The stress-responsive, SK5 subclass, dehydrin gene, CaDHN, has been identified from the Arctic mouse-ear chickweed Cerastium arcticum. CaDHN contains an unusual single cysteine residue (Cys143), which can form intermolecular disulfide bonds. Mutational analysis and a redox experiment confirmed that the dimerization of CaDHN was the result of an intermolecular disulfide bond between the cysteine residues. The biochemical and physiological functions of the mutant C143A were also investigated by in vitro and in vivo assays using yeast cells, where it enhanced the scavenging of reactive oxygen species (ROS) by neutralizing hydrogen peroxide. Our results show that the cysteine residue in CaDHN helps to enhance C. arcticum tolerance to abiotic stress by regulating the dimerization of the intrinsically disordered CaDHN protein, which acts as a defense mechanism against extreme polar environments. | Kim, Il-Sup; Choi, Woong; Park, Ae Kyung; Kim, Hyun; Son, Jonghyeon; Lee, Jun Hyuck; Shin, Seung Chul; Kim, T. Doohun; Kim, Han-Woo | Kyungpook Natl Univ, Adv Bioresource R&D Ctr, Daegu 41566, South Korea; Korea Polar Res Inst, Res Unit Cryogen Novel Mat, Incheon 21990, South Korea; Korea Ctr Dis Control & Prevent, Ctr Lab Control Infect Dis, Div Bacterial Dis, Cheongju 28159, South Korea; Daegu Gyeongbuk Med Innovat Fdn, New Drug Dev Ctr, Daegu 41061, South Korea; Univ Sci & Technol, Dept Polar Sci, Incheon 21990, South Korea; Sookmyung Womens Univ, Grad Sch Gen Studies, Dept Chem, Seoul 04310, South Korea | ; Shin, Seung Chul/LIA-8245-2024; Choi, Woong/AAD-9084-2019; Park, Sue/J-2757-2012 | 55477678200; 57211508168; 57210753537; 57195101304; 55881098100; 57214247889; 55804630100; 7407120687; 22985057300 | 92kis@hanmail.net;woong@kopri.re.kr;parkak1003@gmail.com;insangkh@naver.com;tuutoo92@dgmif.re.kr;junhyucklee@kopri.re.kr;ssc@kopri.re.kr;doohunkim@sookmyung.ac.kr;hwkim@kopri.re.kr; | MOLECULES | MOLECULES | 1420-3049 | 27 | 9 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY;CHEMISTRY, MULTIDISCIPLINARY | 2022 | 4.6 | 33.9 | 0 | 2025-06-25 | 0 | 0 | dehydrin; Arctic mouse-ear chickweed; intermolecular disulfide bond; reactive oxygen species; dimerization; cysteine | EMBRYOGENESIS ABUNDANT PROTEIN; PLANT DEHYDRINS; CITRUS DEHYDRIN; ARABIDOPSIS-THALIANA; STRESS TOLERANCE; METAL-BINDING; WATER-STRESS; LEA PROTEIN; ION-BINDING; GENE | Arctic mouse-ear chickweed; cysteine; dehydrin; dimerization; intermolecular disulfide bond; reactive oxygen species | Animals; Caryophyllaceae; Cysteine; Disulfides; Hydrogen Peroxide; Mice; Oxidation-Reduction; cysteine; disulfide; hydrogen peroxide; animal; Caryophyllaceae; chemistry; mouse; oxidation reduction reaction | English | 2022 | 2022-05 | 10.3390/molecules27092934 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Magnesium and Zinc Oxide Nanoparticles from Datura alba Improve Cognitive Impairment and Blood Brain Barrier Leakage | Epilepsy is a neurological disorder involving persistent spontaneous seizures and uncontrolled neuronal excitability that leads to cognitive impairments and blood-brain barrier (BBB) disruption. Currently available antiepileptic drugs present side effects and researchers are trying to discover new agents with properties to overcome these drawbacks. The aim was to synthesize magnesium oxide (MgO) and zinc oxide (ZnO) nanoparticles from Datura alba fresh leaf extracts and evaluate their anti-epileptic potential in mice kindling or a repetitive seizures model. The phytoassisted synthesized nanoparticles were characterized using spectroscopy; FT-IR, XRD, SEM, and EDX. Analysis of the NPs confirmed the crystalline pleomorphic shape using the salts of both zinc and magnesium possibly stabilized, functionalized and reduced by bioactive molecules present in plant extract. By using several characterization techniques, NPs were confirmed. UV-Vis spectroscopy of biologically produced ZnO and MgO revealed distinctive peaks at 380 nm and 242 nm, respectively. Our findings categorically demonstrated the reductive role of biomolecules in the formation of ZnO and MgO NPs. The mice kindling model was induced using seven injections of Pentylenetetrazole (PTZ, 40 mg/kg, i.p) for 15 days alternatively. The results showed that mice post-treated with either ZnO or MgO nanoparticles (10 mg/kg, i.p) significantly improved in respect of behavior and memory as confirmed in the Morris water maze (MWM), open field (OF), novel object recognition (NOR) test compared with PTZ treated mice. Furthermore, the ZnO and MgO nanoparticle treatment also maintained the integrity of the BBB, reducing the leakage, as confirmed by Evans blue dye (EBD) compared with PTZ treated mice only. In summary, the current finding demonstrates that green synthesized ZnO and MgO nanoparticles have neuroprotective, ant-epileptic potential, molecular mechanisms, and clinical implications need to be further explored. | Ullah, Habib; Ullah, Ikram; Rehman, Gauhar; Hamayun, Muhammad; Ali, Sajid; Rahman, Abdur; Lee, In-Jung | Abdul Wali Khan Univ, Dept Zool, Mardan 23200, Pakistan; Int Islamic Univ, Fac Basic & Appl Sci, Sulaiman Bin Abdullah Aba Al Khail Ctr Interdisci, H-10, Islamabad 44000, Pakistan; Abdul Wali Khan Univ, Dept Bot, Mardan 23200, Pakistan; Yeungnam Univ, Dept Hort & Life Sci, Gyongsan 38541, South Korea; Kyungpook Natl Univ, Dept Appl Biosci, Sch Life Sci, Daegu 41566, South Korea | Lee, In-Jung/GLS-0432-2022; Rehman, Gauhar/AAW-9173-2020; ULLAH, IKRAM/KEI-0622-2024; Rahman, Abdur/JPK-2618-2023; Hamayun, Muhammad/B-1694-2010; Ali, Sajid/GLS-7322-2022 | 57531505500; 59722236700; 35734938700; 59297330100; 57214290889; 57669275500; 16425830900 | zoologist399@gmail.com;ikram.ullah@iiu.edu.pk;gauhar@awkum.edu.pk;hamayun@awkum.edu.pk;drsajid@yu.ac.kr;03149443357ar@gmail.com;ijlee@ku.ac.kr; | MOLECULES | MOLECULES | 1420-3049 | 27 | 15 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY;CHEMISTRY, MULTIDISCIPLINARY | 2022 | 4.6 | 33.9 | 2.03 | 2025-06-25 | 22 | 23 | magnesium oxide; nanoparticles; pentylenetetrazole; Datura alba; blood brain barrier; seizures | GREEN SYNTHESIS | blood brain barrier; Datura alba; magnesium oxide; nanoparticles; pentylenetetrazole; seizures | Animals; Anti-Bacterial Agents; Blood-Brain Barrier; Cognitive Dysfunction; Datura; Magnesium; Magnesium Oxide; Metal Nanoparticles; Mice; Nanoparticles; Plant Extracts; Seizures; Spectroscopy, Fourier Transform Infrared; Zinc Oxide; antiinfective agent; magnesium; magnesium oxide; metal nanoparticle; nanoparticle; plant extract; zinc oxide; animal; blood brain barrier; chemistry; cognitive defect; Datura; infrared spectroscopy; mouse; seizure | English | 2022 | 2022-08 | 10.3390/molecules27154753 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Metal-Induced Fluorescence Quenching of Photoconvertible Fluorescent Protein DendFP | Sensitive and accurate detection of specific metal ions is important for sensor development and can advance analytical science and support environmental and human medical examinations. Fluorescent proteins (FPs) can be quenched by specific metal ions and spectroscopically show a unique fluorescence-quenching sensitivity, suggesting their potential application as FP-based metal biosensors. Since the characteristics of the fluorescence quenching are difficult to predict, spectroscopic analysis of new FPs is important for the development of FP-based biosensors. Here we reported the spectroscopic and structural analysis of metal-induced fluorescence quenching of the photoconvertible fluorescent protein DendFP. The spectroscopic analysis showed that Fe2+, Fe3+, and Cu2+ significantly reduced the fluorescence emission of DendFP. The metal titration experiments showed that the dissociation constants (K-d) of Fe2+, Fe3+, and Cu2+ for DendFP were 24.59, 41.66, and 137.18 mu M, respectively. The tetrameric interface of DendFP, which the metal ions cannot bind to, was analyzed. Structural comparison of the metal-binding sites of DendFP with those of iq-mEmerald and Dronpa suggested that quenchable DendFP has a unique metal-binding site on the beta-barrel that does not utilize the histidine pair for metal binding. | Kim, In Jung; Xu, Yongbin; Nam, Ki Hyun | Korea Univ, Coll Life Sci & Biotechnol, Div Biotechnol, Seoul 02841, South Korea; Kyungpook Natl Univ, Res Inst Tailored Food Technol, Daegu 41566, South Korea; Dalian Minzu Univ, Coll Life Sci, Dept Bioengn, Dalian 116600, Peoples R China; Dalian Minzu Univ, Key Lab Biotechnol & Bioresources Utilizat Minist, Dalian 116024, Peoples R China; Pohang Univ Sci & Technol, Dept Life Sci, Pohang 37673, South Korea; Pohang Univ Sci & Technol, POSTECH Biotech Ctr, Pohang 37673, South Korea | Nam, Ki Hyun/N-6812-2019; Yongbin, Xu/AAS-8750-2020 | 57195531808; 23092421400; 13808340200 | ij0308@korea.ac.kr;yongbinxu@dlnu.edu.cn;structures@postech.ac.kr; | MOLECULES | MOLECULES | 1420-3049 | 27 | 9 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY;CHEMISTRY, MULTIDISCIPLINARY | 2022 | 4.6 | 33.9 | 1.64 | 2025-06-25 | 16 | 17 | metal biosensor; fluorescent protein; DendFP; fluorescence quenching; crystal structure | GREEN; BIOSENSOR | crystal structure; DendFP; fluorescence quenching; fluorescent protein; metal biosensor | English | 2022 | 2022-05 | 10.3390/molecules27092922 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Protective Effects of Orange Sweet Pepper Juices Prepared by High-Speed Blender and Low-Speed Masticating Juicer against UVB-induced Skin Damage in SKH-1 Hairless Mice | Sweet pepper fruits (Capsicum annuum L.) contain various nutrients and phytochemicals that enhance human health and prevent the pathogenesis of certain diseases. Here, we report that oral administration of orange sweet pepper juices prepared by a high-speed blender and low-speed masticating juicer reduces UVB-induced skin damage in SKH-1 hairless mice. Sweet pepper juices reduced UVB-induced skin photoaging by the regulation of genes involved in dermal matrix production and maintenance such as collagen type I alpha 1 and matrix metalloproteinase-2, 3, 9. Administration of sweet pepper juices also restored total collagen levels in UVB-exposed mice. In addition, sweet pepper juices downregulated the expression of pro-inflammatory proteins such as cyclooxygenase-2, interleukin (IL)-1 beta, IL-17, and IL-23, which was likely via inhibiting the NF-kappa B pathway. Moreover, primary antioxidant enzymes in the skin were enhanced by oral supplementation of sweet pepper juices, as evidenced by increased expression of catalase, glutathione peroxidase, and superoxide dismutase-2. Immunohistochemical staining showed that sweet pepper juices reduced UVB-induced DNA damage by preventing 8-OHdG formation. These results suggest that sweet pepper juices may offer a protective effect against photoaging by inhibiting the breakdown of dermal matrix, inflammatory response, and DNA damage as well as enhancing antioxidant defense, which leads to an overall reduction in skin damage. | Van-Long Truong; Rarison, Razanamanana H. G.; Jeong, Woo-Sik | Kyungpook Natl Univ, Coll Agr & Life Sci, Sch Food Sci & Biotechnol, Food & Bioind Res Inst, Daegu 41566, South Korea | Jeong, Woo-Sik/AAN-6885-2020 | 55925363400; 57930282700; 10440750200 | wsjeong@knu.ac.kr; | MOLECULES | MOLECULES | 1420-3049 | 27 | 19 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY;CHEMISTRY, MULTIDISCIPLINARY | 2022 | 4.6 | 33.9 | 0.96 | 2025-06-25 | 8 | 10 | high-speed blender; low-speed masticating juicer; skin health; sweet pepper juice; UVB radiation | NF-KAPPA-B; NORMAL HUMAN KERATINOCYTES; CAPSICUM-ANNUUM L.; ULTRAVIOLET-IRRADIATION; ANTIOXIDANT ACTIVITIES; BETA-CAROTENE; OXIDATIVE STRESS; LIGHT; ACTIVATION; EXPRESSION | high-speed blender; low-speed masticating juicer; skin health; sweet pepper juice; UVB radiation | Animals; Antioxidants; Capsicum; Catalase; Collagen Type I; Cyclooxygenase 2; Glutathione Peroxidase; Humans; Interleukin-17; Interleukin-23; Matrix Metalloproteinase 2; Mice; Mice, Hairless; NF-kappa B; Phytochemicals; Skin; Skin Aging; Ultraviolet Rays; antioxidant; catalase; collagen type 1; cyclooxygenase 2; gelatinase A; glutathione peroxidase; immunoglobulin enhancer binding protein; interleukin 17; interleukin 23; phytochemical; adverse event; animal; cutaneous parameters; hairless mouse; human; metabolism; mouse; pepper; skin; ultraviolet radiation | English | 2022 | 2022-10 | 10.3390/molecules27196394 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Seed Treatment with Illite Enhanced Yield and Nutritional Value of Soybean Sprouts | Soybean sprouts, a nutritional food product, can contribute to food security because they can be grown within a week and do not require sophisticated technology. The yield and quality of soybean sprouts are influenced by various factors, including seed priming and growing conditions. The objective of this study was to investigate the effects of seed soaking in different concentrations of illite, a clay mineral, on the yield and quality of soybean sprouts. Soybean seeds soaked in five concentrations (0.5%, 1%, 3%, 5%, and 10%, w/v) of illite or tap water for 8 h were named IP-0.5, IP-1, IP3, IP-5, IP-10, and control, respectively. The highest sprout yield was found in IP-3, followed by IP-1, and IP-5, which had 11.1%, 8.8%, and 7.4% increments, respectively, compared to the control. The content of vitamin C, mineral element, isoflavone, total polyphenol, and total flavonoid was higher in many of the illite-treated soybean sprouts than in the control. The overall results indicated that pre-soaking soybean seeds in lower concentrations (0.5-3%, w/v) of illite could be helpful to enhance the yield and nutritional value of soybean sprouts in an easy and inexpensive way. | Ha, Man-Chul; Im, Dong-Young; Park, Hung-Soo; Dhungana, Sanjeev Kumar; Kim, Il-Doo; Shin, Dong-Hyun | AOS Co Ltd, Yongsan Myeon 29108, Yeongdong Gun, South Korea; Yeongdong Cty Off, Yeongdong Eup 29140, Yeongdong Gun, South Korea; Rural Dev Adm, Natl Inst Crop Sci, Dept Southern Area Crop Sci, Miryang 50424, South Korea; Kyungpook Natl Univ, Int Inst Res & Dev, Daegu 41566, South Korea; Kyungpook Natl Univ, Sch Appl Biosci, Daegu 41566, South Korea | Dhungana, Sanjeev Kumar/O-4097-2017 | 57450976200; 57451151000; 57450077300; 56269940800; 56269995600; 7403352903 | gidoo11@korea.kr;sanjeevdhungana@yahoo.com;ildookim@hanmail.net;dhshin@knu.ac.kr; | MOLECULES | MOLECULES | 1420-3049 | 27 | 4 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY;CHEMISTRY, MULTIDISCIPLINARY | 2022 | 4.6 | 33.9 | 0.68 | 2025-06-25 | 8 | 7 | antioxidant potential; nutrient; illite powder; soybean sprout; yield | GERMINATED BROWN RICE; MAX L. MERRILL; ANTIOXIDANT ACTIVITY; SULFATE FORTIFICATION; CHEMICAL-COMPOSITION; BIOACTIVE COMPOUNDS; MINERAL ELEMENTS; POTASSIUM; QUALITY; GROWTH | Antioxidant potential; Illite powder; Nutrient; Soybean sprout; Yield | Food Analysis; Humans; Minerals; Nutritive Value; Seedlings; Seeds; Soybeans; illite; mineral; chemistry; food analysis; growth, development and aging; human; metabolism; nutritional value; plant seed; seedling; soybean | English | 2022 | 2022-02 | 10.3390/molecules27041152 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | The Luteolinidin and Petunidin 3-O-Glucoside: A Competitive Inhibitor of Tyrosinase | The enzyme tyrosinase plays a key role in the early stages of melanin biosynthesis. This study evaluated the inhibitory activity of anthocyanidin (1) and anthocyanins (2-6) on the catalytic reaction. Of the six derivatives examined, 1-3 showed inhibitory activity with IC50 values of 3.7 +/- 0.1, 10.3 +/- 1.0, and 41.3 +/- 3.2 mu M, respectively. Based on enzyme kinetics, 1-3 were confirmed to be competitive inhibitors with K-i values of 2.8, 9.0, and 51.9 mu M, respectively. Molecular docking analysis revealed the formation of a binary encounter complex between 1-3 and the tyrosinase catalytic site. Luteolinidin (1) and petunidin 3-O-glucoside (2) may serve as tyrosinase inhibitors to block melanin production. | Yang, Seo Young; Kim, Jang Hoon; Su, Xiangdong; Kim, Jeong Ah | Sangji Univ, Dept Pharmaceut Engn, 83 Sangjidae Gil, Wonju 26339, South Korea; Natl Inst Hort & Herbal Sci, Dept Herbal Crop Res, RDA, Eumseong 27709, South Korea; Sun Yat Sen Univ, Sch Pharmaceut Sci Shenzhen, Shenzhen Campus,66 Gongchang Rd, Shenzhen 518107, Peoples R China; Kyungpook Natl Univ, Coll Pharm, Vessel Organ Interact Res Ctr, VOICE MRC, Daegu 41566, South Korea; Kyungpook Natl Univ, Coll Pharm, BK21 FOUR Community Based Intelligent Novel Drug, Daegu 41566, South Korea; Kyungpook Natl Univ, Res Inst Pharmaceut Sci, Daegu 41566, South Korea | Kim, Jang Hoon/ABU-7953-2022 | 57215036954; 35189109900; 57197769442; 24722570900 | jkim6923@knu.ac.kr; | MOLECULES | MOLECULES | 1420-3049 | 27 | 17 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY;CHEMISTRY, MULTIDISCIPLINARY | 2022 | 4.6 | 33.9 | 0.96 | 2025-06-25 | 9 | 10 | tyrosinase; melanin; anthocyanins; competitive inhibitor; molecular docking | NIGRA L. FRUITS; IN-VITRO; ANTHOCYANINS; EXTRACTION; INSIGHTS | anthocyanins; competitive inhibitor; melanin; molecular docking; tyrosinase | English | 2022 | 2022-09 | 10.3390/molecules27175703 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | A Comparison of Barrier Factors between Hospitals with and without Cardiac Rehabilitation Programs in Korea: A Nation-Wide Survey Research | The percentage of patients undergoing cardiac rehabilitation programs (CRP) is very low (30-40%), and hospitals providing CRP are either insufficient or lacking, even in countries with advanced medical care; therefore, this study aims to investigate the barriers, as well as compare the differences between hospitals, with or without CRP. We conducted a survey, in which the questionnaire was distributed through post or email to 607 specialists who work at 164 hospitals performing percutaneous coronary interventions (PCI). The results were as follows: (1) of the 164 hospitals, 132 responded (response rate: 80.5%). While all 47 hospitals with CRP responded (100%), from among the 117 hospitals without CRP, 85 responded (72.7%). (2) Of the 607 specialists, 227 responded (response rate: 36.9%). The response rates according to specialties were as follows: cardiologists (28.9%), cardiac surgeons (24.5%), and physiatrists (64.1%). (3) While the specialists at hospitals with CRP identified patient referral, transportation, and cost as the major barriers, for those at hospitals without CRP, all items were considered barriers, especially the items related to equipment, space, workforce, and budget as being more serious barriers. Therefore, in order to actively promote CRP, it is suggested that governments consider the customized support system according to the performance of CRPs. | Kim, Chul; Sung, Jidong; Han, Jae-Young; Jee, Sungju; Lee, Jang Woo; Lee, Jong Hwa; Kim, Won-Seok; Bang, Heui Je; Baek, Sora; Joa, Kyung-Lim; Kim, Ae Ryoung; Lee, So Young; Kim, Jihee; Kim, Chung Reen; Kwon, Oh Pum | Inje Univ Sanggye Paik Hosp, Dept Rehabil Med, Seoul 01757, South Korea; Sungkyunkwan Univ, Div Cardiol, Dept Med, Sch Med, Seoul 06351, South Korea; Chonnam Natl Univ, Dept Phys Med & Rehabil, Med Sch & Hosp, Gwangju 61469, South Korea; Chungnam Natl Univ, Dept Rehabil Med, Coll Med, Daejeon 35015, South Korea; Natl Hlth Insurance Serv Ilsan Hosp, Dept Phys Med & Rehabil, Goyang 10444, South Korea; Dong A Univ, Dept Phys Med & Rehabil, Coll Med, Busan 49201, South Korea; Seoul Natl Univ, Dept Rehabil Med, Bundang Hosp, Seongnam 13620, South Korea; Chungbuk Natl Univ Hosp, Dept Rehabil Med, Cheongju 28644, South Korea; Kangwon Natl Univ, Dept Rehabil Med, Sch Med, Chunchon 24289, South Korea; Inha Univ Hosp, Dept Rehabil Med, Incheon 22332, South Korea; Kyungpook Natl Univ, Dept Rehabil Med, Sch Med, Daegu 41944, South Korea; Jeju Natl Univ, Dept Rehabil Med, Sch Med, Jeju 63241, South Korea; Wonkwang Univ, Dept Rehabil Med, Sch Med, Iksan 54538, South Korea; Ulsan Univ, Dept Rehabil Med, Coll Med, Ulsan 44033, South Korea | ; Lee, Jaewon/N-9064-2013; Joa, Kyung-Lim/ABB-3860-2020; Han, Jae-Young/AAV-1100-2021; , 김원석/AAJ-2334-2020 | 55936526100; 57221027209; 15765035600; 56487143900; 55999572900; 55690046100; 57028735900; 55246577800; 55875523200; 55245910100; 57196257330; 57202327370; 55822889900; 35848509700; 55822295300 | josephck@naver.com;jidong.sung@gmail.com;rmhanjy@hanmail.net;jeesungju@gmail.com;medipia@gmail.com;jhlee08@dau.ac.kr;wondol77@gmail.com;bang@chungbuk.ac.kr;sora.baek@kangwon.ac.kr;drjoakl@gmail.com;ryoung20@hanmail.net;bluelsy900@hanmail.net;gold82mouse@hanmail.net;crkim@uuh.ulsan.kr;pum78@naver.com; | JOURNAL OF CLINICAL MEDICINE | J CLIN MED | 2077-0383 | 11 | 9 | SCIE | MEDICINE, GENERAL & INTERNAL | 2022 | 3.9 | 34.0 | 0.64 | 2025-06-25 | 4 | 4 | cardiac rehabilitation; barriers; percutaneous coronary interventions; survey | PARTICIPATION | barriers; cardiac rehabilitation; percutaneous coronary interventions; survey | adult; article; budget; cardiac surgeon; cardiologist; controlled study; e-mail; government; heart rehabilitation; human; Korea; medical care; multicenter study; patient referral; percutaneous coronary intervention; physiatrist; workforce | English | 2022 | 2022-05 | 10.3390/jcm11092560 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Association between High Blood Pressure in the Emergency Department and Cryptogenic Hemoptysis | Hemoptysis is a common cause of emergency department (ED) visits. There is little data about the role of systemic hypertension as a cause of hemoptysis. The aim of this study was to evaluate the association between systemic blood pressure and the unknown etiology of hemoptysis. This retrospective study included consecutive patients who visited the ED owing to hemoptysis and underwent a chest computed tomography between January 2011 and June 2021. Details of the initial blood pressure at the ED visit were compared between two groups with identified and unidentified causes of hemoptysis. In total, 1105 adult patients were included. The etiology of hemoptysis was identified in 1042 patients (94.3%) and remained unidentified in 63 patients (5.7%). The percentage of patients with severe hypertension was significantly higher in patients with unidentified causes of hemoptysis than in those with identified causes (35% vs. 11%, p < 0.001). In multivariate analysis, age, ever-smoker, and initial systolic blood pressure were significantly associated with hemoptysis of unidentified causes. Although further studies are needed, our findings suggest a possible association between high blood pressure and cryptogenic hemoptysis. | Park, Ji Eun; Seo, Jin A.; Cha, Jung Guen; Lim, Jae Kwang; Park, Jongmin; Lee, Yong Hoon; Choi, Sun Ha; Seo, Hyewon; Yoo, Seung Soo; Lee, Shin Yup; Cha, Seung Ick; Park, Jae Yong; Kim, Chang Ho; Lee, Jaehee | Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu 41944, South Korea; Kyungpook Natl Univ, Sch Med, Dept Radiol, Daegu 41944, South Korea | ; Lee, Jun Young/CAI-2335-2022; Choi, Sun Ha/HPD-7234-2023; Lee, Jaehee/S-1697-2018 | 57195437358; 57555138700; 57206855971; 55515341400; 57216463879; 57199022948; 57199723585; 55612130200; 56479781600; 49863712700; 35227126400; 58360293800; 7409873555; 13805476000 | kimch@knu.ac.kr;jaelee@knu.ac.kr; | JOURNAL OF CLINICAL MEDICINE | J CLIN MED | 2077-0383 | 11 | 18 | SCIE | MEDICINE, GENERAL & INTERNAL | 2022 | 3.9 | 34.0 | 0.16 | 2025-06-25 | 0 | 1 | hemoptysis; cryptogenic; hypertension; smoking; etiology | BRONCHIAL ARTERY EMBOLIZATION; MALIGNANT HYPERTENSION; COMPUTED-TOMOGRAPHY; DIAGNOSIS; MANAGEMENT; RARE | cryptogenic; etiology; hemoptysis; hypertension; smoking | anticoagulant agent; antihypertensive agent; antithrombocytic agent; heparin; adult; anthracosis; anticoagulant therapy; aortic dissection; Article; aspergilloma; benign bronchial tumor; bleeding disorder; blood pressure; bronchiectasis; bronchitis; broncholithiasis; bronchoscopy; chronic bronchitis; clinical evaluation; comparative study; congenital blood vessel malformation; contrast enhancement; controlled study; diastolic blood pressure; disease association; disease severity; emergency ward; female; follow up; hemoptysis; human; hypertension; injury; lung abscess; lung cancer; lung disease; lung embolism; major clinical study; male; medical history; middle aged; pneumonia; pulmonary hypertension; radiation fibrosis; radiation pneumonia; retrospective study; smoking; systolic blood pressure; thorax; tuberculosis; vasculitis; x-ray computed tomography | English | 2022 | 2022-09 | 10.3390/jcm11185302 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Clinical Outcomes of Biodegradable versus Durable Polymer Drug Eluting Stents in Rotational Atherectomy: Results from ROCK Registry | Background: The aim of this study was to compare the clinical outcomes of biodegradable polymer (BP) versus durable polymer (DP) drug eluting stents (DES) in patients with calcified coronary lesions who underwent rotational atherectomy (RA) and percutaneous coronary intervention (PCI). Methods: This study was based on a multicenter registry which enrolled patients with calcified coronary artery disease who received PCI using RA during between January 2010 and October 2019 from 9 tertiary centers in Korea. The primary outcome was 3-year all-cause mortality, and the secondary outcomes were cardiovascular death and target-lesion failure. Results: A total of 540 patients who underwent PCI using RA were enrolled with a follow-up period of median 16.1 months. From this registry, 272 patients with PCI using DP-DES and 238 patients with BP-SGDES were selected for analysis. PCI with BP-DES was associated with decreased all-cause mortality after propensity score matching (HR 0.414, CI 0.174-0.988) and multivariate Cox regression analysis (HR 0.458, HR 0.224-0.940). BP-DES was also associated with decreased cardiovascular mortality, but there was no difference in TLF between the two groups. Conclusions: BP-DES were associated with favorable outcomes compared to DP-DES in patients undergoing PCI using RA for calcified coronary lesions. | Kim, Kyung An; Her, Sung-Ho; Lee, Kyusup; Choi, Ik Jun; Lee, Jae-Hwan; Lee, Jang Hoon; Lee, Sang Rok; Lee, Pil Hyung; Lee, Seung-Whan; Yoo, Ki Dong; Lee, Su Nam; Jang, Won Young; Moon, Donggyu; Moon, Keon-Woong; Yun, Kyeong Ho; Lee, Hyun-Jong | Catholic Univ Korea, Coll Med, Dept Cardiol, Seoul St Marys Hosp, Seoul 65091, South Korea; Catholic Univ Korea, Coll Med, Dept Cardiol, St Vincents Hosp, Seoul 65091, South Korea; Catholic Univ Korea, Coll Med, Dept Cardiol, Daejeon St Marys Hosp, Seoul 65091, South Korea; Catholic Univ Korea, Coll Med, Dept Cardiol, Incheon St Marys Hosp, Incheon 21431, South Korea; Chungnam Natl Univ, Sejong Hosp, Coll Med, Dept Cardiol, Sejong 34134, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Coll Med, Dept Internal Med, Daegu 41944, South Korea; Chonbuk Natl Univ Hosp, Dept Cardiol, Jeonju 54907, South Korea; Univ Ulsan, Coll Med, Asan Med Ctr, Dept Cardiol, Seoul 05505, South Korea; Wonkwang Univ Hosp, Reg Cardiocerebrovasc Ctr, Dept Cardiovasc Med, Iksan 54538, South Korea; Sejong Gen Hosp, Dept Internal Med, Bucheon 14754, South Korea | ; Lee, Kyoung/J-5570-2012; Yun, Kyeong Ho/IYS-8810-2023 | 57872084600; 12806475600; 57204923370; 55486997300; 36066387900; 54581258000; 55887032200; 35201186300; 17233718400; 35082999900; 57218696499; 57195753730; 56324177300; 7202376745; 14424664600; 57202973860 | hhhsungho@naver.com;untouchables00@hanmail.net; | JOURNAL OF CLINICAL MEDICINE | J CLIN MED | 2077-0383 | 11 | 21 | SCIE | MEDICINE, GENERAL & INTERNAL | 2022 | 3.9 | 34.0 | 0.16 | 2025-06-25 | 1 | 1 | calcified coronary lesion; rotational atherectomy; second generation drug eluting stent; biodegradable polymer; durable polymer | CORONARY-ARTERY-DISEASE; LONG-TERM OUTCOMES; SINGLE-CENTER; LESIONS; CALCIFICATION; IMPLANTATION; ANGIOPLASTY | biodegradable polymer; calcified coronary lesion; durable polymer; rotational atherectomy; second generation drug eluting stent | acetylsalicylic acid; angiotensin receptor antagonist; beta adrenergic receptor blocking agent; creatine kinase MB; hemoglobin; hydroxymethylglutaryl coenzyme A reductase inhibitor; polymer; purinergic P2Y receptor agonist; adult; age; aged; all cause mortality; Article; biodegradability; body mass; cardiovascular mortality; cause of death; cerebrovascular accident; clinical outcome; coronary artery calcification; coronary stenting; creatine kinase blood level; dyslipidemia; female; follow up; heart left ventricle ejection fraction; hemoglobin blood level; human; Korea; major clinical study; male; multicenter study; non ST segment elevation myocardial infarction; percutaneous coronary intervention; propensity score; rotational atherectomy; silent myocardial ischemia; target lesion revascularization | English | 2022 | 2022-11 | 10.3390/jcm11216251 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Comparison of FibroScan-Aspartate Aminotransferase (FAST) Score and Other Non-invasive Surrogates in Predicting High-Risk Non-alcoholic Steatohepatitis Criteria | Identification of non-alcoholic steatohepatitis (NASH) with high activity and fibrosis is a major priority in patients with non-alcoholic fatty liver disease. We validated the predictive value of the FibroScan-aspartate aminotransferase (FAST) score and other non-invasive fibrosis surrogates in predicting high-risk NASH criteria. This multicenter retrospective study recruited 251 biopsy-proven non-alcoholic fatty liver disease (NAFLD) patients (132 [52.6%] men) between 2011 and 2014. The FAST score was calculated using transient elastography data and aspartate aminotransferase (AST) levels. The NAFLD fibrosis score (NFS), fibrosis-4 index (FIB-4), and AST to platelet ratio index (APRI) were calculated using biochemical data. The area under the receiver operating characteristic curves (AUCs) of the FAST score, liver stiffness, NFS, FIB-4, and APRI were 0.752, 0.718, 0.609, 0.650, and 0.722 for NAFLD activity score (NAS) >= 5 (n = 117, 46.6%); 0.788, 0.754, 0.649, 0.701, and 0.747 for fatty liver inhibition of progression-NASH with histologic activity >= 3 (n = 202, 80.5%); 0.807, 0.806, 0.691, 0.732, and 0.760 for severe disease with activity >= 3 and/or fibrosis >= 3 (n = 132, 52.6%); and 0.714, 0.812, 0.748, 0.738, and 0.669 for NASH with NAS >= 4 and fibrosis >= 2 (n = 70, 27.9%), respectively. The FAST score had the highest AUC for the most high-risk NASH criteria, except for in predicting NAS >= 4 and fibrosis >= 2. The liver stiffness value showed consistently acceptable performance in predicting all high-risk NASH criteria. The FAST score has acceptable performance in identifying high-risk NASH. However, liver stiffness alone was not inferior to the FAST score. | Lee, Jae Seung; Lee, Hye Won; Kim, Beom Kyung; Park, Jun Yong; Kim, Do Young; Ahn, Sang Hoon; Jang, Jae Young; Park, Soo Young; Lee, Hyun Woong; Lee, Chun Kyon; Kim, Seung Up | Yonsei Univ, Dept Internal Med, Coll Med, Seoul, South Korea; Yonsei Univ, Inst Gastroenterol, Coll Med, Seoul, South Korea; Severance Hosp, Yonsei Liver Ctr, Seoul, South Korea; Soonchunhyang Univ, Dept Internal Med, Sch Med, Seoul, South Korea; Kyungpook Natl Univ Hosp, Dept Internal Med, Daegu, South Korea; Gangnam Severance Hosp, Dept Internal Med, Seoul, South Korea; Ilsan Hosp, Dept Internal Med, Natl Hlth Insurance Cooperat, Goyang, South Korea | ; Park, Jun/H-7127-2019; Ahn, Sang Hoon/AFM-2603-2022; Lee, Hye/D-9081-2016; Kim, Sung-Won/J-5409-2012; Kim, Sun/L-4239-2013; LEE, HYUN/ABC-6119-2021; SANG-HOON, AHN/AAV-2600-2020 | 57204060462; 57200110315; 35302925200; 47861376300; 56119929100; 7401989551; 57221679776; 57191674344; 57349302900; 8432467400; 54933821200 | ksukorea@yuhs.ac; | FRONTIERS IN MEDICINE | FRONT MED-LAUSANNE | 2296-858X | 9 | SCIE | MEDICINE, GENERAL & INTERNAL | 2022 | 3.9 | 34.0 | 2.55 | 2025-06-25 | 16 | 16 | fatty liver; non-alcoholic fatty liver disease; non-alcoholic steatohepatitis; liver function tests; fibrosis; elasticity imaging techniques | FATTY LIVER-DISEASE; HEPATOCELLULAR-CARCINOMA; FLIP ALGORITHM; SAF SCORE; VALIDATION; NAFLD; PROGRESSION; MORTALITY; INDEX | elasticity imaging techniques; fatty liver; fibrosis; liver function tests; non-alcoholic fatty liver disease; non-alcoholic steatohepatitis | aspartate aminotransferase; adult; Article; aspartate aminotransferase to platelet ratio index; cohort analysis; controlled study; diagnostic accuracy; diagnostic test accuracy study; female; Fibrosis-4 Index; high risk patient; histopathology; human; human tissue; liver biopsy; liver function test; liver stiffness; major clinical study; male; NAFLD Fibrosis Score; nonalcoholic fatty liver; Nonalcoholic Fatty Liver Disease Activity Score; nonalcoholic steatohepatitis; patient selection; prediction; predictive validity; predictive value; receiver operating characteristic; retrospective study; transient elastography; validation study | English | 2022 | 2022-04-14 | 10.3389/fmed.2022.869190 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Comparison of Graft Materials in Multilayer Reconstruction with Nasoseptal Flap for High-Flow CSF Leak during Endoscopic Skull Base Surgery | Cerebrospinal fluid (CSF) leak is a crucial complication after endoscopic skull base surgery. Therefore, multilayer reconstruction with grafts is as essential as a reconstruction with pedicled flaps. Although widely used, the multilayer technique with autologous fascia lata has drawbacks, such as additional wound and donor site complications. We compared acellular dermal graft and banked homologous fascia lata graft (alternative grafts) with autologous fascia lata graft for high-flow CSF leak repair. We retrospectively enrolled 193 subjects who underwent endoscopic skull base reconstruction with multilayer fascial grafts and nasoseptal flap for high-flow CSF leaks from November 2014 to February 2020 at a single institution. Acellular dermal matrix (ADM), banked homologous fascia lata, and autologous fascia lata were used in 48 (24.9%), 102 (52.8%), and 43 (22.3%) patients, respectively. Postoperative CSF leaks occurred in 23 (11.9%) patients and meningitis in 8 (4.1%). There was no significant difference in postoperative CSF leak (p = 0.36) and meningitis (p = 0.17) across the graft groups. Additionally, we could not find out contributing risk factors for postoperative CSF leak and meningitis. ADM and banked homologous fascia lata are non-inferior to autologous fascia lata for endoscopic skull base reconstruction in water-tight reconstruction or safety without additional donor site morbidities. | Kim, Byung Kil; Kong, Doo-Sik; Nam, Do-Hyun; Hong, Sang Duk | Kyungpook Natl Univ, Chilgok Hosp, Sch Med, Dept Otorhinolaryngol Head & Neck Surg, Daegu 41404, South Korea; Sungkyunkwan Univ, Samsung Med Ctr, Dept Neurosurg, Sch Med, Seoul 06351, South Korea; Sungkyunkwan Univ, Samsung Med Ctr, Dept Otorhinolaryngol Head & Neck Surg, Sch Med, Seoul 06351, South Korea | , Do Hyun Nam/C-9656-2011 | 57469397400; 10144905700; 57190971869; 24072844200 | kkam97@gmail.com; | JOURNAL OF CLINICAL MEDICINE | J CLIN MED | 2077-0383 | 11 | 22 | SCIE | MEDICINE, GENERAL & INTERNAL | 2022 | 3.9 | 34.0 | 1.28 | 2025-06-25 | 7 | 8 | acellular dermal matrix; cerebrospinal fluid leak; fascia lata; skull base; surgery | NASAL SEPTAL FLAP; TRANSSPHENOIDAL APPROACH; FASCIA LATA; SELLAR RECONSTRUCTION; REPAIR; DEFECTS; ANTERIOR; EXPERIENCE; ALLOGRAFT | acellular dermal matrix; cerebrospinal fluid leak; fascia lata; skull base; surgery | gelatin; polyvinyl alcohol sponge; adolescent; adult; aged; allograft; Article; body mass; cerebrospinal fluid flow; child; chondrosarcoma; chordoma; comparative study; controlled study; craniopharyngioma; cross linking; endoscopic surgery; epidermoid cyst; esthesioneuroblastoma; fascia lata; female; gamma knife radiosurgery; human; hypophysis adenoma; image reconstruction; informed consent; liquorrhea; major clinical study; male; malignant teratoma; mature teratoma; medulloblastoma; meningioma; meningitis; nasoseptal flap; olfactory groove meningioma; patient counseling; pedicled skin flap; posterior fossa; postoperative complication; retrospective study; sinonasal adenocarcinoma; sinonasal squamous cell carcinoma; skull surgery; surface property; tissue bank; tumor volume; xanthogranuloma | English | 2022 | 2022-11 | 10.3390/jcm11226711 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Comparison of Multi- and Single-Site Robotic Myomectomy Using the Da Vinci® SP Surgical System: A Propensity Score Matching Analysis | Objective: This study aimed to compare the surgical outcomes between robotic multi-site myomectomy (RMSM) and robotic single-site myomectomy (RSSM), using the da Vinci (R) SP surgical system and perform propensity score matching analysis to ensure inter-group comparability. Methods: This retrospective study included 105 patients who underwent either three-incision RMSM or RSSM using the da Vinci (R) SP surgical system. We retrospectively reviewed and compared surgical outcomes using 1:1 propensity score matching. Results: After 1:1 propensity score matching, there were no differences in the total operation time and estimated blood loss between the groups. The docking time (p < 0.0001) and duration of hospital stay (p = 0.0001) were significantly shorter in the RSSM group than in the RMSM group. Conclusions: The surgical outcomes of RSSM were comparable to those of RMSM. Moreover, compared to RMSM, RSSM using the da Vinci (R) SP surgical system has shorter docking and morcellation times, and duration of hospital stay. | Kim, Jong Mi; Lee, Yoon Hee; Chong, Gun Oh; Lee, Sae Rom; Hong, Dae Gy | Kyungpook Natl Univ, Sch Med, Dept Obstet & Gynecol, Daegu 41944, South Korea; Kyungpook Natl Univ, Dept Obstet & Gynecol, Chilgok Hosp, Daegu 41404, South Korea; Kyungpook Natl Univ, Clin Omics Res Ctr, Sch Med, Daegu 41566, South Korea | 57212764251; 37088851700; 23099068000; 57998635200; 26656670100 | yhlee1017@knu.ac.kr;gochong@knu.ac.kr; | JOURNAL OF CLINICAL MEDICINE | J CLIN MED | 2077-0383 | 11 | 23 | SCIE | MEDICINE, GENERAL & INTERNAL | 2022 | 3.9 | 34.0 | 1.12 | 2025-06-25 | 8 | 7 | robotic myomectomy; robotic multi-site myomectomy; robotic single-site myomectomy; da Vinci (R) SP surgical system; propensity score matching | LAPAROSCOPIC MYOMECTOMY; HYSTERECTOMY | da Vinci<sup>®</sup> SP surgical system; propensity score matching; robotic multi-site myomectomy; robotic myomectomy; robotic single-site myomectomy | adult; Article; clinical outcome; female; human; intermethod comparison; length of stay; major clinical study; male; medical record review; myomectomy; operation duration; operative blood loss; propensity score; retrospective study; robot assisted surgery; time | English | 2022 | 2022-12 | 10.3390/jcm11236905 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Comparison of the Malignant Predictors in Intrahepatic and Extrahepatic Intraductal Papillary Neoplasm of the Bile Duct | Background: Intraductal papillary neoplasm of the bile duct (IPNB) is a precancerous lesion of cholangiocarcinoma, for which surgical resection is the most effective treatment. We evaluated the predictors of malignancy in IPNB according to anatomical location and the prognosis without surgery. Methods: A total of 196 IPNB patients who underwent pathologic confirmation by surgical resection or endoscopic retrograde cholangiography or percutaneous transhepatic cholangioscopic biopsy were included. Clinicopathological findings of IPNB with invasive carcinoma or mucosal dysplasia were analyzed according to anatomical location. Results: Of the 116 patients with intrahepatic IPNB (I-IPNB) and 80 patients with extrahepatic IPNB (E-IPNB), 62 (53.4%) and 61 (76.3%) were diagnosed with invasive carcinoma, respectively. Multivariate analysis revealed that mural nodule > 12 mm (p = 0.043) in I-IPNB and enhancement of mural nodule (p = 0.044) in E-IPNB were predictive factors for malignancy. For pathologic discrepancy before and after surgery, IPNB has a 71.2% sensitivity and 82.3% specificity. In the non-surgical IPNB group, composed of nine I-IPNB and seven E-IPNB patients, 43.7% progressed to IPNB with invasive carcinoma within 876 days. Conclusions: E-IPNB has a higher rate of malignancy than I-IPNB. The predictive factor for malignancy is mural nodule > 12 mm in I-IPNB and mural nodule enhancement in E-IPNB. | Han, Sung Yong; Kim, Dong Uk; Nam, Hyeong Seok; Kang, Dae Hwan; Jang, Sung Ill; Lee, Dong Ki; Shin, Dong Woo; Cho, Kwang Bum; Yang, Min Jae; Hwang, Jae Chul; Kim, Jin Hong; So, Hoonsub; Bang, Sung Jo; Sung, Min Je; Chang-Il Kwon; Lee, Dong Wook; Cho, Chang-Min; Cho, Jae Hee | Pusan Natl Univ, Pusan Natl Univ Hosp, Biomed Res Inst, Dept Internal Med,Sch Med, Busan 49241, South Korea; Pusan Natl Univ, Yangsan Hosp, Res Inst Convergence Biomed Sci & Technol, Dept Internal Med,Sch Med, Yangsan 50612, South Korea; Yonsei Univ, Gangnam Severance Hosp, Dept Internal Med, Coll Med, Seoul 06230, South Korea; Keimyung Univ, Dongsan Med Ctr, Dept Internal Med, Sch Med, Daegu 42601, South Korea; Ajou Univ, Dept Gastroenterol, Sch Med, Suwon 16499, South Korea; Univ Ulsan, Ulsan Univ Hosp, Dept Internal Med, Coll Med, Ulsan 44033, South Korea; CHA Univ, Digest Dis Ctr, CHA Bundang Med Ctr, Sch Med, Seongnam 13497, South Korea; Kyungpook Natl Univ, Dept Internal Med, Sch Med, Daegu 42601, South Korea | Cho, Jae Hee/AAL-8192-2020; Kang, Dae/A-4703-2011; KIM, SUHWAN/GSE-0120-2022 | 57190127827; 55742956600; 56799876600; 23090971800; 43761242600; 26029189500; 56258304500; 7403956834; 55964785900; 7403897612; 56255862100; 56023799500; 8431257400; 57217149653; 14819477200; 57202974895; 57158287600; 58838319500 | mirsaint@hanmail.net;amlm3@hanmail.net;skyace27@hanmail.net;sulsulpul@naver.com;aerojsi88@gmail.com;dklee@yuhs.ac;delight0618@naver.com;chokb@dsmc.or.kr;creator1999@hanmail.net;cath07@naver.com;jinhkim@ajou.ac.kr;hoon3112@gmail.com;sjbang@uuh.ulsan.kr;mj1744@hanmail.net;mdkwon@naver.com;storm5333@naver.com;changmincho@gmail.com;jhcho9328@gmail.com; | JOURNAL OF CLINICAL MEDICINE | J CLIN MED | 2077-0383 | 11 | 7 | SCIE | MEDICINE, GENERAL & INTERNAL | 2022 | 3.9 | 34.0 | 0.8 | 2025-06-25 | 7 | 5 | intraductal papillary neoplasm of the bile duct; prognosis; natural course; cholangiocarcinoma; predictor | FEATURES | cholangiocarcinoma; intraductal papillary neoplasm of the bile duct; natural course; predictor; prognosis | alanine aminotransferase; alkaline phosphatase; bilirubin; C reactive protein; CA 19-9 antigen; carcinoembryonic antigen; gamma glutamyltransferase; abdominal pain; aged; alanine aminotransferase blood level; alkaline phosphatase blood level; anatomical location; Article; biliary tract endoscopy; bilirubin blood level; body mass; cancer growth; cancer patient; cancer prognosis; cholangitis; clinical feature; controlled study; diabetes mellitus; endoscopic retrograde cholangiopancreatography; extrahepatic cholangiocarcinoma; female; fever; follow up; gamma glutamyl transferase blood level; hepatitis B; hepatitis C; human; hypertension; intraductal papillary neoplasm of the bile duct; intrahepatic cholangiocarcinoma; jaundice; leukocyte count; liver cirrhosis; lymphadenopathy; major clinical study; male; malignant transformation; medical record review; percutaneous biopsy; percutaneous transhepatic cholangioscopic biopsy; predictive value; retrospective study; sensitivity and specificity; sex ratio; very elderly | English | 2022 | 2022-04 | 10.3390/jcm11071985 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | Erratum | Corrigendum: Customized Color Settings of Digitally Assisted Vitreoretinal Surgery to Enable Use of Lower Dye Concentrations During Macular Surgery (Front. Med., (2022), 8, (810070), 10.3389/fmed.2021.810070) | In the original article, we neglected to include the funder “Korea Health Industry Development Institute (KHIDI), Grant number: HI15C0001” in the Funding section. It should be “This work was supported by Biomedical Research Institute grant, Kyungpook National University Hospital (2018). This research was supported by a grant of the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI), funded by the Ministry of Health andWelfare, Republic of Korea (Grant number: HI15C0001).” In the published article, there was an error in affiliation 1. Instead of “Department of Ophthalmology, School of Medicine, Kyungpook National University Hospital, Kyungpook National University, Daegu, South Korea,” it should be “Department of Ophthalmology, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, South Korea.” The authors apologize for these errors and state that this does not change the scientific conclusions of the article in any way. The original article has been updated. Copyright © 2022 Park, Do, Shin and Park. | Park, Su Jin; Do, Jae Rock; Shin, Jae Pil; Park, Dong Ho | Department of Ophthalmology, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, South Korea; Department of Ophthalmology, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, South Korea; Department of Ophthalmology, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, South Korea; Department of Ophthalmology, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, South Korea, Kyungpook National University Bio-Medical Research Institute, Daegu, South Korea, Kyungpook National University Cell and Matrix Research Institute, Daegu, South Korea | 57194422330; 58600232100; 56517350400; 36676632900 | dongho_park@knu.ac.kr; | Frontiers in Medicine | FRONT MED-LAUSANNE | N/A | 2296-858X | 9 | SCIE | MEDICINE, GENERAL & INTERNAL | 2022 | 3.9 | 34.0 | 0 | 2025-06-25 | 0 | 25 gauge pars plana vitrectomy; epiretinal membrane (ERM); ILM peeling; macular surgery; vitrectomy | erratum | English | Final | 2022 | 10.3389/fmed.2022.901546 | 바로가기 | 바로가기 | 바로가기 | ||||||||
| ○ | ○ | Article | COVID-19 and related social distancing measures induce significant metabolic complications without prominent weight gain in Korean adults | BackgroundThis study using multi-center health examination data from Korean adults was conducted to confirm changes in weight, and their related cardiometabolic parameters, before and after strengthening of social distancing regulations. MethodsA retrospective cohort study was conducted using health check-up data from 13 university hospitals. The study period was from January 2018 to July 2020. To examine the effect of systematic social distancing measures, participants who underwent a health check-up (Visit 3) between July 2020 and July 2021 (during full scale social distancing), and had undergone two previous health check-ups (Visits 1 and 2) between January 2018 and June 2020 (before social distancing), were selected. In total, data from 7,875 participants were analyzed. Linear mixed-effect models were used to calculate estimates of anthropometric indices and metabolic markers measured on Visits 2 and 3, compared with measurements from Visit 1. ResultsThere were no significant differences in body weight, body mass index, waist circumference, and body composition on Visit 3 than on Visits 1 and 2. However, the odds of metabolic syndrome and its components, including hypertension, high glucose, diabetes, hypercholesterolemia, hypertriglyceridemia, hyper-non-high-density lipoprotein cholesterolemia, and dyslipidemia were significantly higher on Visit 3 than on Visits 1 and 2. The increase in metabolic complications was marked, particularly in relatively young adults who visited health check-up centers located in the capital area. ConclusionMetabolic syndrome and its components were significantly worse after high level social distancing, although there were no significant increases in anthropometric indices and body fat levels. Healthcare providers need to prevent and manage worsening of metabolic parameters in subpopulations prone to be more sedentary and eat unhealthy food during the COVID-19 pandemic and associated social distancing measures. | Ko, Hae-Jin; Cho, Yoon Jeong; Kim, Kyoung-Kon; Kang, Jee-Hyun; Kim, Young-Sang; Haam, Ji-Hee; Hur, Yang-Im; Choi, Hye-In; Lee, Kyu Rae; Park, Jung Ha; Cho, Soo Hyun; Kim, Jong-Koo; Lee, Taesic; Seo, Myung-Jae; Yoon, Yeong Sook; Seo, Yoobin; Nam, Ga Eun; Kim, Sun Hyun | Kyungpook Natl Univ Hosp, Sch Med, Dept Family Med, Daegu, South Korea; Daegu Catholic Univ, Dept Family Med, Sch Med, Daegu, South Korea; Gachon Univ, Gil Med Ctr, Dept Family Med, Coll Med, Incheon, South Korea; Konyang Univ, Dept Family Med, Coll Med, Daejeon, South Korea; CHA Univ, CHA Bundang Med Ctr, Dept Family Med, Seongnam, South Korea; CHA Univ, Chaum Life Ctr, Seoul, South Korea; Jeju Natl Univ Hosp, Dept Family Med, Jeju, South Korea; Chung Ang Univ Hosp, Coll Med, Dept Family Med, Seoul, South Korea; Yonsei Univ, Dept Family Med, Wonju Coll Med, Wonju, South Korea; Inje Univ, Dept Family Med, Ilsan Paik Hosp, Goyang, South Korea; Wonkwang Univ, Sanbon Med Ctr, Sch Med, Dept Family Med, Gunpo Si, South Korea; Korea Univ Guro Hosp, Korea Univ Coll Med, Dept Family Med, Seoul, South Korea; Catholic Kwandong Univ Coll Med, Int St Marys Hosp, Dept Family Med, Int St, Incheon, South Korea | Kim, Kyoung-Kon/GXV-1730-2022; Cho, Soo Hyun/AAZ-4770-2021; Seo, Yoobin/GXH-8953-2022; Nam, Ga Eun/AAU-6055-2020; Park, Jin-Young/HDN-0483-2022; Kim, Sun/C-2026-2011; Lee, Taesic/IQU-2971-2023; Lee, Kyurae/J-8766-2019 | 54393415700; 55676577200; 8385516200; 56283070200; 57196173327; 56685485400; 52363748600; 57202001023; 24472041300; 57219448110; 57225917692; 35215202400; 57193750794; 57279475100; 8659033200; 57814053700; 49561817000; 56042294700 | zaduplum@aim.com; | FRONTIERS IN MEDICINE | FRONT MED-LAUSANNE | 2296-858X | 9 | SCIE | MEDICINE, GENERAL & INTERNAL | 2022 | 3.9 | 34.0 | 0.48 | 2025-06-25 | 3 | 3 | body weight changes; COVID-19; metabolic syndrome; obesity; physical distancing; weight gain | LOCKDOWN | body weight changes; COVID-19; metabolic syndrome; obesity; physical distancing; weight gain | adult; Article; body composition; body fat percentage; body mass; body weight; body weight gain; cohort analysis; comorbidity; coronavirus disease 2019; diabetes mellitus; dyslipidemia; female; follow up; human; hypercholesterolemia; hypertension; hypertriglyceridemia; Korean (people); major clinical study; male; metabolic syndrome X; obesity; prevalence; retrospective study; social distancing; university hospital; waist circumference | English | 2022 | 2022-09-07 | 10.3389/fmed.2022.951793 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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