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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Article | Copper-Catalyzed Synthesis of Trinuclear N-Fused Hybrid Scaffolds by Double C(sp²)-N Bond Formation between 2-(2-Bromoaryl)indoles and 2-Aminoazoles | 2-(2-Bromoaryl)indoles react with 2-aminoazoles by microwave irradiation in DMF in the presence of a catalytic amount of CuI and a base to produce trinuclear N-fused hybrid scaffolds, benzo[4,5]imidazo[1,2-a]indolo[1,2-c]quinazolines and imidazo[1,2-a]indolo[1,2-c]quinazolines in moderate to good yields. The reaction seems to proceed via copper-catalyzed C(sp(2))-N coupling and subsequent intramolecular cyclocondensation accompanied by ammonia evolution. Complete regioselective C-N cyclization is observed with the reaction of 2-(2-bromophenyl)indole with 2-aminoazoles. | Diep, Thi Duyen; Duy Quang Dao, Pham; Ho, Son Long; Cho, Chan Sik | Kyungpook Natl Univ, Dept Appl Chem, 80 Daehakro, Daegu 41566, South Korea | ; Ho, Son Long/P-3183-2015; Dao, P. D. Quang/AAR-9880-2021 | 57209421320; 57194217171; 55659242700; 7403100019 | cscho@knu.ac.kr; | EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | EUR J ORG CHEM | 1434-193X | 1099-0690 | 2020 | 19 | SCIE | CHEMISTRY, ORGANIC | 2020 | 3.021 | 37.7 | 1.06 | 2025-06-25 | 14 | 14 | Cyclization; Nitrogen heterocycles; C-N bond formation; 2-Aminoazoles; Homogeneous catalysis | BENZIMIDAZOLE-4,7-DIONES; COUPLING/CYCLIZATION; HYDRODEHALOGENATION; CYCLIZATION; ARYLATION | 2-Aminoazoles; Cyclization; C–N bond formation; Homogeneous catalysis; Nitrogen heterocycles | English | 2020 | 2020-05-22 | 10.1002/ejoc.202000238 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Synthesis of 2-Aminoquinazoline- and 2-Aminopyrimidine-Fused Hybrid Scaffolds by Copper-Catalyzed C(sp²)-N Coupling and Cyclization Followed by Oxidation | 2-(2-Bromoaryl)- and 2-(2-bromovinyl)-4,7-dimethoxybenzimidazoles are coupled and cyclized with cyanamide as a building block in dimethylformamide in the presence of a catalytic amount of a copper catalyst along with a base to give the corresponding 2-aminoquinazoline- and 2-aminopyrimidine-fused 4,7-dimethoxybenzimidazoles in good yields. Subsequent oxidation of such N-fused hybrid scaffolds by treatment of ceric ammonium nitrate in acetonitrile/H2O affords unprecedented 2-aminoquinazoline- and 2-aminopyrimidine-fused benzimidazolequinones. | Kwak, Jung Pyo; Dao, Pham Duy Quang; Cho, Chan Sik | Kyungpook Natl Univ, Dept Appl Chem, 80 Daehakro, Daegu 41566, South Korea | Dao, P. D. Quang/AAR-9880-2021 | 57216922222; 57194217171; 7403100019 | cscho@knu.ac.kr; | EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | EUR J ORG CHEM | 1434-193X | 1099-0690 | 2020 | 23 | SCIE | CHEMISTRY, ORGANIC | 2020 | 3.021 | 37.7 | 0.98 | 2025-06-25 | 10 | 13 | Copper; Cross-coupling; Cyclization; Nitrogen heterocycles; Oxidation | ARYLBORONIC ACIDS SYNTHESIS; FUSED BENZIMIDAZOLE-4,7-DIONES; C-C; HETEROCYCLIC QUINONES; BIOLOGICAL EVALUATION; POTENTIAL ANTITUMOR; EFFICIENT SYNTHESIS; CASCADE REACTIONS; DOMINO SYNTHESIS; TANDEM REACTION | Copper; Cross-coupling; Cyclization; Nitrogen heterocycles; Oxidation | English | 2020 | 2020-06-23 | 10.1002/ejoc.202000427 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Inhibition of MAGEA2 regulates pluripotency, proliferation, apoptosis, and differentiation in mouse embryonic stem cells | Mouse embryonic stem cells (mESCs) exhibit self-renewal and pluripotency, can differentiate into all three germ layers, and serve as an essential model in stem cell research and for potential clinical application in regenerative medicine. Melanoma-associated antigen A2 (MAGEA2) is not expressed in normal somatic cells but rather in different types of cancer, especially in undifferentiated cells, such as in the testis, differentiating cells, and ESCs. However, the role of MAGEA2 in mESCs remains to be clarified. Accordingly, in this study, we examined the expression and functions of MAGEA2 in mESCs. MAGEA2 messenger RNA (mRNA) expression was decreased during mESCs differentiation. MAGEA2 function was then evaluated in knockdown mESC. MAGEA2 knockdown resulted in decreased pluripotency marker gene expression in mESCs consequent to increased Erk1/2 phosphorylation. Decreased MAGEA2 expression inhibited mESC proliferation via S phase cell cycle arrest with a subsequent decrease in cell cycle-associated genes Cdk1, Cdk2, Cyclin A1, Cyclin D1, and Cdc25a. Apoptotic mESCs markedly increased along with cleaved forms of caspases 3, 6, and 7 and PARP expression, confirming caspase-dependent apoptosis. MAGEA2 knockdown significantly decreased embryoid body size in vitro when cells were differentiated naturally and teratoma size in vivo, concomitant with decreased ectoderm marker gene expression. These findings suggested that MAGEA2 regulates ESC pluripotency, proliferation, cell cycle, apoptosis, and differentiation. The enhanced understanding of the regulatory mechanisms underlying diverse mESC characteristics will facilitate the clinical application of mESCs. | Park, Song; Han, Jee Eun; Kim, Hyeon-Gyeom; Kim, Hee-Yeon; Kim, Min-Gi; Park, Jin-Kyu; Cho, Gil-Jae; Huang, Hai; Kim, Myoung Ok; Ryoo, Zae Young; Han, Se-Hyeon; Choi, Seong-Kyoon | DGIST, Core Prot Resources Ctr, Daegu, South Korea; Kyungpook Natl Univ, Coll Vet Med, Daegu, South Korea; Kyungpook Natl Univ, Sch Life Sci, BK21 Plus KNU Creat BioRes Grp, Daegu, South Korea; Kyungpook Natl Univ, Sch Anim BT Sci, Sangju Si, Gyeongsangbuk D, South Korea; Hanyang Univ, Sch Media Commun, Wangsibri Ro 222, Seoul 04763, South Korea; DGIST, Div Biotechnol, Daegu 42988, South Korea | RYOO, ZAEYOUNG/AAQ-1573-2020 | 57139047900; 57214671240; 57210911747; 58368914700; 59075131900; 35213723500; 7201438083; 57215021952; 8934745900; 16937104900; 57210915063; 55505432500 | han382@daum.net;cskbest@dgist.ac.kr; | JOURNAL OF CELLULAR BIOCHEMISTRY | J CELL BIOCHEM | 0730-2312 | 1097-4644 | 121 | 11 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY;CELL BIOLOGY | 2020 | 4.429 | 37.8 | 0.19 | 2025-06-25 | 3 | 3 | apoptosis; differentiation; MAGEA2; pluripotency; proliferation | SELF-RENEWAL; SMALL MOLECULES; EXPRESSION; ROLES; NANOG; IDENTIFICATION; MAINTENANCE; ACTIVATION; PATHWAYS; PROTEINS | apoptosis; differentiation; MAGEA2; pluripotency; proliferation | Animals; Apoptosis; Cell Cycle; Cell Differentiation; Cell Proliferation; Cells, Cultured; Humans; Male; Melanoma-Specific Antigens; Mice; Mice, Inbred BALB C; Mice, Nude; Mouse Embryonic Stem Cells; Pluripotent Stem Cells; Teratoma; alkaline phosphatase; beta actin; caspase 3; caspase 6; caspase 7; cyclin A1; cyclin D1; cyclin dependent kinase 1; cyclin dependent kinase 2; cyclin dependent kinase 4; cyclin dependent kinase 6; hepatocyte nuclear factor 3beta; liver receptor homolog 1; melanoma antigen; melanoma associated antigen A10; melanoma associated antigen A2; melanoma associated antigen A4; melanoma associated antigen A6; melanoma associated antigen A8; messenger RNA; mitogen activated protein kinase 1; mitogen activated protein kinase 3; nerve cell adhesion molecule; neurogenic differentiation factor; noggin; octamer transcription factor 4; transcription factor GATA 4; transcription factor PAX6; transcription factor Sox17; transcription factor Sox2; unclassified drug; melanoma antigen; animal cell; animal experiment; animal model; apoptosis; Article; cell differentiation; cell proliferation; cell self-renewal; controlled study; ectoderm; embryo; embryoid body; embryonic stem cell; flow cytometry; gene; gene expression; gene knockdown; in vitro study; male; marker gene; mouse; mRNA expression level; nonhuman; priority journal; protein expression; protein function; protein phosphorylation; S phase cell cycle checkpoint; signal transduction; animal; Bagg albino mouse; cell culture; cell cycle; cell differentiation; cytology; genetics; human; metabolism; mouse embryonic stem cell; nude mouse; pathology; pluripotent stem cell; teratoma | English | 2020 | 2020-11 | 10.1002/jcb.29692 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | A novel class based searching algorithm in small world internet of drone network | Internet of Drones (IoD) is a new area which is based on incorporation of social networks into Internet of Things (IoT). In near future the social network of IoT devices is expected to be highly convoluted due to the exponential growth of heterogeneous smart devices. Searching the right objects and services in optimal time through best path will be a challenging task. Information searching techniques in IoD need efficient schemes and innovative research. The Small World phenomenon reveals some alluring facts and has been motivating many researchers to understand the behavior of social networks. Inspired by information searching mechanisms in drone networks, an information searching algorithm which exploits rating of services in IoD, is proposed in this work. Results show that the proposed information searching algorithm proves to be efficient with its mean execution time not over than 2.5 ms on two different machines. | Rehman, Abdul; Paul, Anand; Ahmad, Awais; Jeon, Gwanggil | Kyungpook Natl Univ, Daegu, South Korea; Univ Milan, Milan, Italy; Incheon Natl Univ, Incheon, South Korea | Paul, Anand/V-6724-2017; Ahmad, Awais/AAA-4504-2019; Rehman, Abdul/D-5630-2019 | 57200894071; 56650522400; 57224336715; 15022497800 | paul.editor@gmail.com; | COMPUTER COMMUNICATIONS | COMPUT COMMUN | 0140-3664 | 1873-703X | 157 | SCIE | COMPUTER SCIENCE, INFORMATION SYSTEMS;ENGINEERING, ELECTRICAL & ELECTRONIC;TELECOMMUNICATIONS | 2020 | 3.167 | 37.9 | 0.87 | 2025-06-25 | 11 | 17 | Information search; Class based search; IoD; Small world; Drone assistant | BIG DATA; SMART CITY; THINGS; COMMUNICATION | Class based search; Drone assistant; Information search; IoD; Small world | Drones; Information retrieval; Social networking (online); Efficient schemes; Exponential growth; Information searching; Innovative research; Internet of Things (IOT); Searching algorithms; Small World Phenomenon; Smart devices; Internet of things | English | 2020 | 2020-05-01 | 10.1016/j.comcom.2020.03.040 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | A Query based Information search in an Individual's Small World of Social Internet of Things | Recently, the consolidation of Social Network and the Internet of Things (IoT) acquiring appreciation and consideration among researchers due to its immense and adaptable behavior. Social Internet of Things (SIoT) comprehends the adequacy to support the inventive applications and network services with adept and persuasive demeanors. The author's exertion for this research provides the subsistence to the SIoT amelioration Currently, the SIoT technique proven to be competent, but the exponential growth of heterogeneous smart devices may arise a challenging scenario. Searching the right object, service, or best path to the informative nodes in such highly convoluted networks is always a challenging task. This research strengthen the SIoT paradigm by consolidating the properties of the individual's Small World. In addition, this research also advises a Smart Social Agent (SSA) to minimize the human intervention. The absolute objective of this paper is twofold, (i) transformation of SIoT network into Individual's Small World SIoT network, (ii) searching the right information efficiently by exploiting SSA. To accomplish the goal we have proposed an efficient Query based Searching algorithm which exploits Service Oriented properties of Individual's Small World SIoT network and searches information. First result shows the significant alleviation in the network complexity, reduces the average path length, and network diameter. Eventually, it improves the network scalability and navigability. While second result shows that the proposed Query based searching algorithm proves to be efficient with its mean execution time not more than 2.66 ms for complete network on two different machines. Whereas, for Individual's small world network the mean execution time is not more than 2.47 ms for both machine. | Rehman, Abdul; Paul, Anand; Ahmad, Awais | Kyungpook Natl Univ, Daegu, South Korea; Univ Milan, Milan, Italy | Ahmad, Awais/AAA-4504-2019; Rehman, Abdul/D-5630-2019; Paul, Anand/V-6724-2017 | 57200894071; 56650522400; 57224336715 | anand@knu.ac.kr; | COMPUTER COMMUNICATIONS | COMPUT COMMUN | 0140-3664 | 1873-703X | 163 | SCIE | COMPUTER SCIENCE, INFORMATION SYSTEMS;ENGINEERING, ELECTRICAL & ELECTRONIC;TELECOMMUNICATIONS | 2020 | 3.167 | 37.9 | 0.69 | 2025-06-25 | 14 | 18 | Information search; Query based search; SIoT; Small world; Smart Social Agent (SSA); Social network | SMART CITY; IOT; COMMUNICATION; NETWORKS | Information search; Query based search; SIoT; Small world; Smart Social Agent (SSA); Social network | Small-world networks; Average path length; Exponential growth; Human intervention; Information search; Internet of thing (IOT); Network complexity; Network scalability; Searching algorithms; Internet of things | English | 2020 | 2020-11-01 | 10.1016/j.comcom.2020.08.027 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Complete Genome Sequence of Pseudomonas psychrotolerans CS51, a Plant Growth-Promoting Bacterium, Under Heavy Metal Stress Conditions | In the current study, we aimed to elucidate the plant growth-promoting characteristics of Pseudomonas psychrotolerans CS51 under heavy metal stress conditions (Zn, Cu, and Cd) and determine the genetic makeup of the CS51 genome using the single-molecule real-time (SMRT) sequencing technology of Pacific Biosciences. The results revealed that inoculation with CS51 induced endogenous indole-3-acetic acid (IAA) and gibberellins (GAs), which significantly enhanced cucumber growth (root shoot length) and increased the heavy metal tolerance of cucumber plants. Moreover, genomic analysis revealed that the CS51 genome consisted of a circular chromosome of 5,364,174 base pairs with an average G+C content of 64.71%. There were around 4774 predicted protein-coding sequences (CDSs) in 4859 genes, 15 rRNA genes, and 67 tRNA genes. Around 3950 protein-coding genes with function prediction and 733 genes without function prediction were identified. Furthermore, functional analyses predicted that the CS51 genome could encode genes required for auxin biosynthesis, nitrate and nitrite ammonification, the phosphate-specific transport system, and the sulfate transport system, which are beneficial for plant growth promotion. The heavy metal resistance of CS51 was confirmed by the presence of genes responsible for cobalt-zinc-cadmium resistance, nickel transport, and copper homeostasis in the CS51 genome. The extrapolation of the curve showed that the core genome contained a minimum of 2122 genes (95% confidence interval = 2034.24 to 2080.215). Our findings indicated that the genome sequence of CS51 may be used as an eco-friendly bioresource to promote plant growth in heavy metal-contaminated areas. | Kang, Sang-Mo; Asaf, Sajjad; Khan, Abdul Latif; Lubna; Khan, Adil; Mun, Bong-Gyu; Khan, Muhammad Aaqil; Gul, Humaira; Lee, In-Jung | Kyungpook Natl Univ, Sch Appl Biosci, Daegu 41566, South Korea; Univ Nizwa, Nat & Med Sci Res Ctr, Nizwa 616, Oman; Abdul Wali Khan Univ Mardan, Dept Bot, Garden Campus, Mardan 23200, Pakistan | Mun, BongGyu/GYD-6010-2022; Asaf, Sajjad/ABA-3647-2021; Khan, Adil/AAC-5160-2022; Khan, Abdul/H-5910-2011; Kang, Sang-Mo/MBG-7823-2025; Lee, In-Jung/GLS-0432-2022; Khan, Muhammad/ABB-9797-2021 | 56189696900; 56595059900; 26639372800; 57200621537; 57200917937; 57147241300; 57188585606; 7003592765; 16425830900 | kmoya@hanmail.net;sajadasif2000@gmail.com;latifepm78@yahoo.co.uk;lubnabila168@gmail.com;adilsafi122333@gmail.com;mun0301@naver.com;agil_bacha@yahoo.com;gulhumaira@awkum.edu.pk;ijlee@knu.ac.kr; | MICROORGANISMS | MICROORGANISMS | 2076-2607 | 8 | 3 | SCIE | MICROBIOLOGY | 2020 | 4.128 | 37.9 | 2.42 | 2025-06-25 | 59 | 64 | Pseudomonas psychrotolerans; genome sequencing; plant growth promotion; gibberellin biosynthesis; heavy metal resistance; pan-genome | COPPER RESISTANCE GENES; LEIFSONIA-XYLI SE134; SP NOV.; XANTHOMONAS-CAMPESTRIS; SALMONELLA-TYPHIMURIUM; MAGNESIUM TRANSPORT; RHIZOBACTERIA PGPR; INDOLEACETIC-ACID; BACILLUS-SUBTILIS; SPHINGOMONAS SP | Genome sequencing; Gibberellin biosynthesis; Heavy metal resistance; Pan-genome; Plant growth promotion; Pseudomonas psychrotolerans | English | 2020 | 2020-03 | 10.3390/microorganisms8030382 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Flexible functional split for cost-efficient C-RAN | In this paper, we propose flexible functional split schemes for a multi-tier C-RAN architecture based on the concept of virtual remote radio heads (V-RRHs), aiming at optimizing the resource utilization while reducing the overall cost of BBU pool. A V-RRH consists of a digital unit (DU) that hosts a few baseband (BB) processing functionalities and a radio unit (RU) with RF functionality. Specifically, three types of V-RRHs differing in the number of BB processing function slices are considered in three functional split options. We aim at finding the optimal functional split option for each task and thus allocate the appropriate function slice block (FSB) of BBU pool for it. The issue of optimally allocating FSBs to tasks is normalized as a zero-one (0-1) packing problem which is NP-complete. To solve the 0-1 packing problem, we divide it into three stages and solve them by a pure integer non-linear programming (PINLP) model. Numerical results show that the proposed flexible functional split strategies comprehensively outperform the existing C-RAN and D-RAN schemes in terms of the overall cost. | Mei, Haoran; Peng, Limei | Kyungpook Natl Univ, Sch Comp Sci & Engn, Deagu 41566, South Korea | 57208655106; 7201574271 | meihaoran@knu.ac.kr;auroraplm@knu.ac.kr; | COMPUTER COMMUNICATIONS | COMPUT COMMUN | 0140-3664 | 1873-703X | 161 | SCIE | COMPUTER SCIENCE, INFORMATION SYSTEMS;ENGINEERING, ELECTRICAL & ELECTRONIC;TELECOMMUNICATIONS | 2020 | 3.167 | 37.9 | 0.44 | 2025-06-25 | 9 | 11 | C-RAN; Flexible functional split; 5G network | 5G network; C-RAN; Flexible functional split | Integer programming; Nonlinear programming; Cost-efficient; Numerical results; Overall costs; Packing problems; Processing functionality; RAN architecture; Remote radio heads; Resource utilizations; Digital radio | English | 2020 | 2020-09-01 | 10.1016/j.comcom.2020.07.029 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Genome Wide Analysis Reveals the Role of VadA in Stress Response, Germination, and Sterigmatocystin Production in Aspergillus nidulans Conidia | In the Aspergillus species, conidia are asexual spores that are infectious particles responsible for propagation. Conidia contain various mycotoxins that can have detrimental effects in humans. Previous study demonstrated that VadA is required for fungal development and spore viability in the model fungus Aspergillus nidulans. In the present study, vadA transcriptomic analysis revealed that VadA affects the mRNA expression of a variety of genes in A. nidulans conidia. The genes that were primarily affected in conidia were associated with trehalose biosynthesis, cell-wall integrity, stress response, and secondary metabolism. Genetic changes caused by deletion of vadA were related to phenotypes of the vadA deletion mutant conidia. The deletion of vadA resulted in increased conidial sensitivity against ultraviolet stress and induced germ tube formation in the presence and absence of glucose. In addition, most genes in the secondary metabolism gene clusters of sterigmatocystin, asperfuranone, monodictyphenone, and asperthecin were upregulated in the mutant conidia with vadA deletion. The deletion of vadA led to an increase in the amount of sterigmatocystin in the conidia, suggesting that VadA is essential for the repression of sterigmatocystin production in conidia. These results suggest that VadA coordinates conidia maturation, stress response, and secondary metabolism in A. nidulans conidia. | Son, Ye-Eun; Park, Hee-Soo | Kyungpook Natl Univ, Sch Food Sci & Biotechnol, Daegu 41566, South Korea; Kyungpook Natl Univ, Dept Integrat Biol, Daegu 41566, South Korea | Park, Hee-Soo/AAC-6422-2019 | 57200513491; 15751448400 | thsdpdms0407@naver.com;phsoo97@knu.ac.kr; | MICROORGANISMS | MICROORGANISMS | 2076-2607 | 8 | 9 | SCIE | MICROBIOLOGY | 2020 | 4.128 | 37.9 | 0.46 | 2025-06-25 | 12 | 12 | VadA; conidia; RNA-seq; ultraviolet stress; sterigmatocystin; germination; Aspergillus nidulans | CELL-WALL; GENE; ORGANIZATION; FUMIGATUS; RESOURCE | Aspergillus nidulans; Conidia; Germination; RNA-seq; Sterigmatocystin; Ultraviolet stress; VadA | English | 2020 | 2020-09 | 10.3390/microorganisms8091319 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Genotypic Analysis of Piroplasms and Associated Pathogens from Ticks Infesting Cattle in Korea | Tick-borne pathogens (TBPs) impose an important limitation to livestock production worldwide, especially in subtropical and tropical areas. Earlier studies in Korea have examined TBPs residing in ticks and animals; however, information on multiple TBPs in ticks infesting cattle is lacking. This study assessed the prevalence of TBPs in ticks parasitizing cattle. A total of 576 ticks, including 340 adults and 236 nymphs, were collected from cattle in Korea between 2014 and 2018. All ticks collected were identified as Haemaphysalis longicornis based on their morphological and molecular characteristics. Among piroplasms and other tick-associated pathogens, seven TBP genes, namely Theileria orientalis (5.0%), Anaplasma bovis (2.3%), Anaplasma capra (4.7%), Anaplasma phagocytophilum-like Anaplasma spp. (APL) clades A (1.9%) and B (0.5%), Ehrlichia canis (1.6%), and Candidatus Rickettsia longicornii (17.5%), were detected. Bartonella spp. and severe fever with thrombocytopenia syndrome virus were not found. To our knowledge, this is the first study to report the presence of the pathogens T. orientalis major piroplasm surface protein genotypes 3 and 7, A. capra, and APL in ticks from Korea. Cattle ticks may be maintenance hosts for many TBPs, and veterinary and medical clinicians should be aware of their high probability of infection and clinical complexity in humans. | Seo, Min-Goo; Kwon, Oh-Deog; Kwak, Dongmi | Anim & Plant Quarantine Agcy, Vet Drugs & Biol Div, 177 Hyeoksin 8 Ro, Gimcheon 39660, Gyeongbuk, South Korea; Kyungpook Natl Univ, Coll Vet Med, Dept Vet Med, 80 Daehak Ro, Daegu 41566, South Korea; Kyungpook Natl Univ, Cardiovasc Res Inst, 680 Gukchaebosang Ro, Daegu 41944, South Korea | ; Seo, Min-Goo/NQF-4335-2025 | 53982155300; 7402195886; 7007148758 | koreasmg@korea.kr;odkwon@knu.ac.kr;dmkwak@knu.ac.kr; | MICROORGANISMS | MICROORGANISMS | 2076-2607 | 8 | 5 | SCIE | MICROBIOLOGY | 2020 | 4.128 | 37.9 | 0.92 | 2025-06-25 | 19 | 21 | tick-borne pathogens; phylogeny; Theileria; Anaplasma; Ehrlichia; Rickettsia; Haemaphysalis longicornis | ANAPLASMA-PHAGOCYTOPHILUM; MOLECULAR-DETECTION; PHYLOGENETIC ANALYSIS; THEILERIA-ORIENTALIS; BORNE RICKETTSIOSES; SURFACE PROTEIN; HUMAN INFECTION; GRAZING CATTLE; EHRLICHIA; DISEASES | Anaplasma; Ehrlichia; Haemaphysalis longicornis; Phylogeny; Rickettsia; Theileria; Tick-borne pathogens | English | 2020 | 2020-05 | 10.3390/microorganisms8050728 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Isolation and Investigation of Potential Non-Saccharomyces Yeasts to Improve the Volatile Terpene Compounds in Korean Muscat Bailey A Wine | The Muscat Bailey A (MBA) grape, one of the most prominent grape cultivars in Korea, contains considerable amounts of monoterpene alcohols that have very low odor thresholds and significantly affect the perception of wine aroma. To develop a potential wine starter for Korean MBA wine, nine types of non-Saccharomyces yeasts were isolated from various Korean food materials, including nuruk, Semillon grapes, persimmons, and Muscat Bailey A grapes, and their physiological, biochemical, and enzymatic properties were investigated and compared to the conventional wine fermentation strain, Saccharomyces cerevisiae W-3. Through API ZYM analysis, Wickerhamomyces anomalus JK04, Hanseniaspora vineae S7, Hanseniaspora uvarum S8, Candida railenensis S18, and Metschnikowia pulcherrima S36 were revealed to have beta-glucosidase activity. Their activities were quantified by culturing in growth medium composed of different carbon sources: 2% glucose, 1% glucose + 1% cellobiose, and 2% cellobiose. W. anomalus JK04 and M. pulcherrima S36 showed the highest beta-glucosidase activities in all growth media; thus, they were selected and utilized for MBA wine fermentation. MBA wines co-fermented with non-Saccharomyces yeasts (W. anomalus JK04 or M. pulcherrima S36) and S. cerevisiae W-3 showed significantly increased levels of linalool, citronellol, and geraniol compared to MBA wine fermented with S. cerevisiae W-3 (control). In a sensory evaluation, the flavor, taste, and overall preference scores of the co-fermented wines were higher than those for the control wine, suggesting that W. anomalus JK04 and M. pulcherrima S36 are favorable wine starters for improving Korean MBA wine quality. | Lee, Sae-Byuk; Park, Heui-Dong | Kyungpook Natl Univ, Sch Food Sci & Biotechnol, 80 Daehakro, Daegu 41566, South Korea; Kyungpook Natl Univ, Inst Fermentat Biotechnol, 80 Daehakro, Daegu 41566, South Korea | 57188742752; 7601568590 | lsbyuck@nate.com;hpark@knu.ac.kr; | MICROORGANISMS | MICROORGANISMS | 2076-2607 | 8 | 10 | SCIE | MICROBIOLOGY | 2020 | 4.128 | 37.9 | 1.38 | 2025-06-25 | 34 | 38 | non-Saccharomyces yeasts; MBA wine; Fermentation; β -glucosidase; volatile aromatic compound | AROMA-ENHANCING CAPABILITIES; BETA-GLUCOSIDASE; PICHIA-ANOMALA; CO-FERMENTATION; GRAPE JUICE; CEREVISIAE; TOLERANCE; DIVERSITY; STARTER; QUALITY | Fermentation; MBA wine; Non-Saccharomyces yeasts; Volatile aromatic compound; β-glucosidase | English | 2020 | 2020-10 | 10.3390/microorganisms8101552 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Link quality and energy utilization based preferable next hop selection routing for wireless body area networks | The rising population and cost of medical services triggered the new technologies including Wireless Body Area Networks (WBANs) based on smart and intelligent biosensors nodes for sensing and monitoring the patient vital signs. The biosensor nodes have implanted inside or outside the human body to send the medical information to medical centers. For data dissemination in these services, different types of solutions and model have been designed to address the interference, body movement, disconnection quality of services issues in the network. This paper presents an Energy Aware Routing (EAR) protocol to minimize energy utilization and select preferable next hop by evaluating the link quality of sensor nodes. The proposed protocol evaluates the energy level, link quality, and remaining energy level to balance the load, minimize the energy utilization, and enhance the data transmission. Various simulations have conducted to evaluate the proposed protocols performance in terms of energy consumption, data delivery, delay, and data throughput. Experimental results indicated that the proposed protocol has a better mechanism for date routing and better solution to minimize the energy of sensor nodes in WBANs. | Qureshi, Kashif Naseer; Din, Sadia; Jeon, Gwanggil; Piccialli, Francesco | Bahria Univ, Dept Comp Sci, Islamabad, Pakistan; Kyungpook Natl Univ, Sch Comp Sci & Engn, Daegu, South Korea; Xidian Univ, Sch Elect Engn, Xian 710071, Shaanxi, Peoples R China; Incheon Natl Univ, Dept Embedded Syst Engn, Incheon 22012, South Korea | ; Din, Sadia/ADU-4679-2022; Piccialli, Francesco/ABC-2457-2020; Qureshi, Kashif/AAJ-1052-2020 | 55781386200; 57188997144; 15022497800; 42762051900 | kashifnq@gmail.com;saadia.deen@gmail.com;ggjeon@gmail.com;francesco.piccialli@unina.it; | COMPUTER COMMUNICATIONS | COMPUT COMMUN | 0140-3664 | 1873-703X | 149 | SCIE | COMPUTER SCIENCE, INFORMATION SYSTEMS;ENGINEERING, ELECTRICAL & ELECTRONIC;TELECOMMUNICATIONS | 2020 | 3.167 | 37.9 | 4.49 | 2025-06-25 | 72 | 101 | Energy efficiency; Routing; Link quality; Interference; Energy consumption; Data delivery | COMMUNICATION; INTERNET | Data delivery; Energy consumption; Energy efficiency; Interference; Link quality; Routing | Biosensors; Energy efficiency; Energy utilization; Quality control; Sensor nodes; Wave interference; Wireless local area networks (WLAN); Data delivery; Data dissemination; Energy-aware routing; Link quality; Medical information; Remaining energies; Routing; Wireless body area network; Power management (telecommunication) | English | 2020 | 2020-01 | 10.1016/j.comcom.2019.10.030 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Correction | Link quality and energy utilization based preferable next hop selection routing for wireless body area networks (vol 149, pg 382, 2020) | Qureshi, K. N.; Din, S.; Jeon, G.; Piccialli, F. | Bahria Univ, Dept Comp Sci, Islamabad, Pakistan; Kyungpook Natl Univ, Sch Comp Sci & Engn, Daegu, South Korea; Xidian Univ, Sch Elect Engn, Xian 710071, Peoples R China; Univ Naples Federico II, Dept Math & Applicat R Caccioppoli, Naples, Italy | Qureshi, Kashif/AAJ-1052-2020; Din, Sadia/ADU-4679-2022; Piccialli, Francesco/ABC-2457-2020 | 55781386200; 57188997144; 15022497800; 42762051900 | knaseer.buic@bahria.edu.pk;gjeon@gmail.com; | COMPUTER COMMUNICATIONS | COMPUT COMMUN | 0140-3664 | 1873-703X | 155 | SCIE | COMPUTER SCIENCE, INFORMATION SYSTEMS;ENGINEERING, ELECTRICAL & ELECTRONIC;TELECOMMUNICATIONS | 2020 | 3.167 | 37.9 | 0 | 2025-06-25 | 0 | 0 | English | 2020 | 2020-04-01 | 10.1016/j.comcom.2019.12.031 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||||||
| ○ | ○ | Article | Metabolic Changes Induced by Deletion of Transcriptional Regulator GCR2 in Xylose-Fermenting Saccharomyces cerevisiae | Glucose repression has been extensively studied in Saccharomyces cerevisiae, including the regulatory systems responsible for efficient catabolism of glucose, the preferred carbon source. However, how these regulatory systems would alter central metabolism if new foreign pathways are introduced is unknown, and the regulatory networks between glycolysis and the pentose phosphate pathway, the two major pathways in central carbon metabolism, have not been systematically investigated. Here we disrupted gcr2, a key transcriptional regulator, in S. cerevisiae strain SR7 engineered to heterologously express the xylose-assimilating pathway, activating genes involved in glycolysis, and evaluated the global metabolic changes. gcr2 deletion reduced cellular growth in glucose but significantly increased growth when xylose was the sole carbon source. Global metabolite profiling revealed differential regulation of yeast metabolism in SR7-gcr2 Delta, especially carbohydrate and nucleotide metabolism, depending on the carbon source. In glucose, the SR7-gcr2 Delta mutant showed overall decreased abundance of metabolites, such as pyruvate and sedoheptulose-7-phosphate, associated with central carbon metabolism including glycolysis and the pentose phosphate pathway. However, SR7-gcr2 Delta showed an increase in metabolites abundance (ribulose-5-phosphate, sedoheptulose-7-phosphate, and erythrose-4-phosphate) notably from the pentose phosphate pathway, as well as alteration in global metabolism when compared to SR7. These results provide insights into how the regulatory system GCR2 coordinates the transcription of glycolytic genes and associated metabolic pathways. | Shin, Minhye; Kim, Soo Rin | Seoul Natl Univ, Dept Agr Biotechnol, Res Inst Agr & Life Sci, Seoul 08826, South Korea; Kyungpook Natl Univ, Sch Food Sci & Biotechnol, Daegu 41566, South Korea | Kim, Soo Rin/X-2192-2019 | 57208401604; 36659584200 | mhshin1984@snu.ac.kr;soorinkim@knu.ac.kr; | MICROORGANISMS | MICROORGANISMS | 2076-2607 | 8 | 10 | SCIE | MICROBIOLOGY | 2020 | 4.128 | 37.9 | 0.23 | 2025-06-25 | 2 | 5 | GCR2; glycolysis; pentose phosphate pathway; xylose; metabolomics | MASS-SPECTROMETRY; EXPRESSION; ACTIVATION; FERMENTATION; ACCUMULATION; PATHWAY; GENES; PHO13 | GCR2; Glycolysis; Metabolomics; Pentose phosphate pathway; Xylose | English | 2020 | 2020-10 | 10.3390/microorganisms8101499 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Modulation of Gut Microbiota in Korean Navy Trainees following a Healthy Lifestyle Change | Environmental factors can influence the composition of gut microbiota, but understanding the combined effect of lifestyle factors on adult gut microbiota is limited. Here, we investigated whether changes in the modifiable lifestyle factors, such as cigarette smoking, alcohol consumption, sleep duration, physical exercise, and body mass index affected the gut microbiota of Korean navy trainees. The navy trainees were instructed to stop smoking and alcohol consumption and follow a sleep schedule and physical exercise regime for eight weeks. For comparison, healthy Korean civilians, who had no significant change in lifestyles for eight weeks were included in this study. A total of 208 fecal samples were collected from navy trainees (n = 66) and civilians (n = 38) at baseline and week eight. Gut flora was assessed by sequencing the highly variable region of the 16S rRNA gene. The alpha-and beta -diversity of gut flora of both the test and control groups were not significantly changed after eight weeks. However, there was a significant difference among individuals. Smoking had a significant impact in altering alpha-diversity. Our study showed that a healthy lifestyle, particularly cessation of smoking, even in short periods, can affect the gut microbiome by enhancing the abundance of beneficial taxa and reducing that of harmful taxa. | Jung, YeonGyun; Tagele, Setu Bazie; Son, HyunWoo; Ibal, Jerald Conrad; Kerfahi, Dorsaf; Yun, Hyunju; Lee, Bora; Park, Clara Yongjoo; Kim, Eun Soo; Kim, Sang-Jun; Shin, Jae-Ho | Kyungpook Natl Univ, Sch Appl Biosci, Daegu 41566, South Korea; Univ Gondar, Dept Appl Plant Sci, Gondar 196, Ethiopia; Keimyung Univ, Dept Biol Sci, Daegu 42601, South Korea; Chonnam Natl Univ, Dept Food & Nutr, Gwangju 61186, South Korea; Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu 41944, South Korea; Republ Korea Naval Acad, Dept Nat Sci, Chang Won 51702, South Korea | ; Tagele, Setu Bazie/IYJ-1959-2023; Ibal, Jerald/JYQ-0493-2024; Kim, Sang/J-5398-2012 | 57197833801; 57202007103; 57218872919; 57196117664; 55893822900; 57218872276; 57218872497; 56566950900; 57203086704; 55547081800; 57224125922 | jyg1076@knu.ac.kr;setubazie@gmail.com;thsgusdn2@knu.ac.kr;jerald.ibal@gmail.com;kerfahi.dorsaf@gmail.com;virt0323@naver.com;lbr1074@naver.com;parkcy@jnu.ac.kr;dandy813@hanmail.net;sjkim1963@navy.mil.kr;jhshin@knu.ac.kr; | MICROORGANISMS | MICROORGANISMS | 2076-2607 | 8 | 9 | SCIE | MICROBIOLOGY | 2020 | 4.128 | 37.9 | 0.63 | 2025-06-25 | 13 | 12 | gut microbiome; lifestyle; smoking cessation; alpha-diversity; beta-diversity; Bifidobacterium | PRIMARY PREVENTION; STABILITY; BIFIDOBACTERIUM; LACTOBACILLUS; INFLAMMATION; CONSEQUENCES; ASSOCIATION; MICROFLORA; EXPRESSION; DYSBIOSIS | Alpha-diversity; Beta-diversity; Bifidobacterium; Gut microbiome; Lifestyle; Smoking cessation | English | 2020 | 2020-09 | 10.3390/microorganisms8091265 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Molecular Identification of Borrelia afzelii from Ticks Parasitizing Domestic and Wild Animals in South Korea | Lyme borreliosis is one of the most prevalent tick-borne infectious zoonotic diseases caused by spirochetes of the Borrelia burgdorferi sensu lato group. The present study assessed the risk factors and prevalence of Lyme borreliosis in ticks parasitizing domestic and wild animals. A total of 589 ticks (329 tick pools) collected from animals were identified as Haemaphysalis longicornis, (85.7%), H. flava (10.0%), and Ixodes nipponensis (4.3%) using morphological and molecular methods in South Korea. In this study, the 5S-23S gene sequences of B. afzelii (6/329, 1.8%) were detected in ticks taken from mammals, including ticks from horses (2/147 pools, 1.4%), wild boar (1/19 pools, 5.3%), native Korean goats (NKG, 2/34 pools, 5.9%), and Korean water deer (1/129 pools, 0.8%). Unfortunately, ospA, pyrG, and flagellin genes were not able to be amplified in the present study. To our knowledge, our results are the first inclusive data available for B. afzelii circulation in several tick species taken from NKG, horses, and wild boar in South Korea. We believe that the current findings extend our knowledge of the distribution and possible vector spectrum of Borrelia spp. We recommend continuous evaluation of the potential public health threat posed by Borrelia infected ticks. | Seo, Min-Goo; Kwon, Oh-Deog; Kwak, Dongmi | Anim & Plant Quarantine Agcy, Vet Drugs & Biol Div, 177 Hyeoksin 8 Ro, Gimcheon 39660, Gyeongbuk, South Korea; Kyungpook Natl Univ, Coll Vet Med, 80 Daehak Ro, Daegu 41566, South Korea; Kyungpook Natl Univ, Cardiovasc Res Inst, 680 Gukchaebosang Ro, Daegu 41944, South Korea | Seo, Min-Goo/NQF-4335-2025 | 53982155300; 7402195886; 7007148758 | koreasmg@korea.kr;odkwon@knu.ac.kr;dmkwak@knu.ac.kr; | MICROORGANISMS | MICROORGANISMS | 2076-2607 | 8 | 5 | SCIE | MICROBIOLOGY | 2020 | 4.128 | 37.9 | 0.35 | 2025-06-25 | 12 | 12 | Borrelia afzelii; phylogeny; tick; domestic and wild animals | BURGDORFERI SENSU-LATO; FRAGMENT-LENGTH-POLYMORPHISM; JAPONICA SP-NOV; LYME-DISEASE; RELAPSING FEVER; BORNE PATHOGENS; RIBOSOMAL-RNA; GYEONGGI-DO; HORSES; DNA | Borrelia afzelii; Domestic and wild animals; Phylogeny; Tick | English | 2020 | 2020-05 | 10.3390/microorganisms8050649 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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