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WoS SCOPUS Document Type Document Title Abstract Authors Affiliation ResearcherID (WoS) AuthorsID (SCOPUS) Author Email(s) Journal Name JCR Abbreviation ISSN eISSN Volume Issue WoS Edition WoS Category JCR Year IF JCR (%) FWCI FWCI Update Date WoS Citation SCOPUS Citation Keywords (WoS) KeywordsPlus (WoS) Keywords (SCOPUS) KeywordsPlus (SCOPUS) Language Publication Stage Publication Year Publication Date DOI JCR Link DOI Link WOS Link SCOPUS Link
Article A 1-Year Prospective Comparative Study of Sutureless Flanged Intraocular Lens Fixation and Conventional Sutured Scleral Fixation in Intraocular Lens Dislocation Purpose: To compare surgical outcomes of sutureless flanged intraocular lens (IOL) fixation and conventional sutured scleral fixation (SF) for secondary IOL implantation in patients with IOL dislocation. Methods: This is a prospective, comparative cohort study on 103 consecutive patients (103 eyes) with IOL dislocation who underwent vitrectomy with IOL removal and sutured SF (53 eyes) or flanged IOL fixation (50 eyes). Operating time, best-corrected visual acuity (BCVA), refractive difference, IOL tilt and decentration using swept-source anterior segment OCT, and postoperative complications were measured for 12 months. Results: Operating time was significantly shorter for the flanged IOL fixation than for sutured SF (19.4 +/- 4.6 vs. 48.9 +/- 5.2 min, p < 0.001). BCVA in both groups improved at 1, 3, 6, and 12 months postoperatively (p < 0.05). BCVA in the 2 groups was similar during the 12 months of observation. The refractive difference, IOL tilt, IOL decentration, and incidence of postoperative complications were also not different in the 2 groups. Conclusion: Sutured SF and flanged IOL fixation had similar visual outcomes and IOL stability in patients with IOL dislocation. However, the operating time for flanged IOL fixation was less than half that of the sutured SF. This technique is an efficient alternative for treating IOL dislocation. Do, Jae Rock; Park, Su Jin; Mukai, Ryo; Kim, Hong Kyun; Shin, Jae Pil; Park, Dong Ho Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Ophthalmol, 130 Dongdeok Ro, Daegu 41944, South Korea; Sungkyunkwan Univ, Dept Ophthalmol, Sch Med, Samsung Changwon Hosp, Chang Won, South Korea; Gunma Univ, Grad Sch Med, Dept Ophthalmol, Maebashi, Gumma, Japan Kim, Hong Kyun/ITT-7758-2023 58600232100; 57194422330; 13402728800; 57218260940; 56517350400; 36676632900 DongHo_Park@knu.ac.kr; OPHTHALMOLOGICA OPHTHALMOLOGICA 0030-3755 1423-0267 244 1 SCIE OPHTHALMOLOGY 2021 3.757 34.7 4.01 2025-07-30 31 33 Intraocular lens dislocation; Sutureless flanged fixation; Vitrectomy; Vitreoretinal surgery Intraocular lens dislocation; Sutureless flanged fixation; Vitrectomy; Vitreoretinal surgery Cohort Studies; Humans; Lens Subluxation; Lenses, Intraocular; Postoperative Complications; Prospective Studies; Retrospective Studies; Sclera; Suture Techniques; Visual Acuity; adult; anterior eye segment; Article; best corrected visual acuity; clinical outcome; cohort analysis; comparative study; conventional sutured scleral fixation; female; flanged intraocular lens fixation; human; incidence; macular edema; major clinical study; male; muscle hypotonia; operation duration; optical coherence tomography; postoperative complication; prospective study; surgical technique; sutureless technique; vitreous hemorrhage; lens implant; lens subluxation; postoperative complication; retrospective study; sclera; surgery; suture technique; visual acuity English 2021 2021-02 10.1159/000507713 바로가기 바로가기 바로가기 바로가기
Article Consistency of Helicobacter pylori eradication rates of first-line concomitant and sequential therapies in Korea: A nationwide multicenter retrospective study for the last 10 years Background Eradication rate of standard triple therapy for H. pylori has declined to unacceptable level, and alternative regimens such as concomitant and sequential therapy have been introduced. We aimed to assess the consistency of eradication rates of concomitant and sequential therapies as for the first-line H. pylori eradication in Korea. Methods A nationwide multicenter retrospective study was conducted including 18 medical centers from January 2008 to December 2017. We included 3,800 adults who had test to confirm H. pylori eradication within 1 year after concomitant or sequential therapy. Results Concomitant and sequential therapy were prescribed for 2508 and 1292 patients, respectively. The overall eradication rate of concomitant therapy was significantly higher than that of sequential therapy (91.8% vs. 86.1%, p < .001). In time trend analysis, the eradication rates of concomitant therapy were 90.2%, 88.2%, 92.1%, 94.3%, 91.1%, and 93.4% for each year from 2012 to 2017 with an increasing trend (p = .0146), while those of ST showed no significant trend (p = .0873). Among 263 patients with second-line therapy, bismuth quadruple therapy showed significantly higher eradication rate than quinolone-based triple therapy (73.9% vs. 51.5% in ITT analysis, p = .001; 82.7% vs. 63.0% in PP analysis, p = .002). Conclusion Concomitant therapy is the best regimen for the first-line H. pylori eradication showing consistently higher eradication rate with an increasing trend for the last 10 years in Korea. Bismuth quadruple therapy should be considered for second-line therapy after eradication failure using non-bismuth quadruple therapy. Lee, Bong Eun; Kim, Joon Sung; Kim, Byung-Wook; Kim, Jie-Hyun; Kim, Jin Il; Chung, Jun-Won; Jeon, Seong Woo; Lee, Jeong Hoon; Kim, Ji Hyun; Kim, Nayoung; Lee, Ju Yup; Seo, Seung Young; Park, Seon-Young; Kim, Sung Eun; Joo, Moon Kyung; Song, Hyun Joo; Kim, Ki Bae; Bang, Chang Seok; Kim, Hyun Jin Pusan Natl Univ, Dept Internal Med, Sch Med, Busan, South Korea; Catholic Univ Korea, Coll Med, Dept Internal Med, Incheon St Marys Hosp, Incheon, South Korea; Yonsei Univ, Gangnam Severance Hosp, Dept Internal Med, Coll Med, Seoul, South Korea; Catholic Univ Korea, Coll Med, Dept Internal Med, Yeouido St Marys Hosp, Incheon, South Korea; Gachon Univ, Dept Internal Med, Coll Med, Incheon, South Korea; Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu, South Korea; Univ Ulsan, Asan Med Ctr, Dept Internal Med, Coll Med, Seoul, South Korea; Inje Univ, Busan Paik Hosp, Dept Internal Med, Coll Med, Busan, South Korea; Seoul Natl Univ, Dept Internal Med, Coll Med, Seoul, South Korea; Seoul Natl Univ, Liver Res Inst, Coll Med, Seoul, South Korea; Keimyung Univ, Dept Internal Med, Sch Med, Dongsan Med Ctr, Daegu, South Korea; Chonbuk Natl Univ, Chonbuk Natl Univ Hosp, Dept Internal Med, Med Sch, Jeonju, South Korea; Chonnam Natl Univ, Dept Internal Med, Sch Med, Gwangju, South Korea; Kosin Univ, Dept Internal Med, Coll Med, Busan, South Korea; Korea Univ, Dept Internal Med, Coll Med, Guro Hosp, Seoul, South Korea; Jeju Natl Univ, Dept Internal Med, Sch Med, Jeju, South Korea; Chungbuk Natl Univ, Dept Internal Med, Coll Med, Cheongju, South Korea; Hallym Univ, Dept Internal Med, Coll Med, Chunchon, South Korea; Gyeongsang Natl Univ Hosp, Dept Internal Med, Jinju, South Korea Kim, Nayoung/J-5387-2012; Lee, Jae/AAD-3704-2019; KIM, SUNG/ADF-8559-2022; Kim, Woo/D-2733-2015; Kim, Ki Bae/KYQ-0127-2024; Kim, Jie-Hyun/Q-9061-2019; Jeon, Seongwoo/AAU-4618-2020; Bang, Chang SEOK/I-9689-2019; Lee, In/J-9324-2013; Chung, Jun-Won/AAX-4365-2021; Song, hyunjoo/GWC-1292-2022; Kim, Hyungjin/ABC-6057-2021 36461131900; 25932931200; 57216356690; 49461401400; 58252089900; 14065855500; 9733636500; 57219957826; 57218494603; 57201181440; 55891683700; 56883674300; 7501833800; 58848142900; 35313509000; 57217466923; 56106965700; 55935614800; 57201620344 gastro@catholic.as.kr; HELICOBACTER HELICOBACTER 1083-4389 1523-5378 26 2 SCIE GASTROENTEROLOGY & HEPATOLOGY;MICROBIOLOGY 2021 5.182 34.7 0.63 2025-07-30 6 7 concomitant therapy; Helicobacter pylori; sequential therapy; time trend analysis TRIPLE THERAPY; INFECTION concomitant therapy; Helicobacter pylori; sequential therapy; time trend analysis Adult; Amoxicillin; Anti-Bacterial Agents; Drug Therapy, Combination; Helicobacter Infections; Helicobacter pylori; Humans; Proton Pump Inhibitors; Republic of Korea; Retrospective Studies; amoxicillin; bismuth; esomeprazole; lansoprazole; metronidazole; omeprazole; pantoprazole; quinoline derived antiinfective agent; rabeprazole; tetracycline; amoxicillin; antiinfective agent; proton pump inhibitor; abdominal pain; adult; Article; bitter taste; comorbidity; controlled study; diarrhea; disease eradication; drug efficacy; drug safety; female; follow up; Helicobacter infection; Helicobacter pylori; human; intention to treat analysis; major clinical study; male; nausea; nonhuman; retrospective study; side effect; South Korea; treatment outcome; trend study; vomiting; clinical trial; combination drug therapy; Helicobacter pylori; multicenter study English 2021 2021-04 10.1111/hel.12780 바로가기 바로가기 바로가기 바로가기
Article Effects of 1-methylcyclopropene and aminoethoxyvinylglycine treatments on fruit quality and antioxidant metabolites in cold-stored 'Sangjudungsi' persimmons After harvest, 'Sangjudungsi' persimmon (Diospyros kaki Thunb.) fruit quickly soften and develop physiological disorders during cold storage. The objective of this study was to evaluate the effectiveness of 1-methylcyclopropene (1-MCP) and aminoethoxyvinylglycine (AVG) treatments on fruit quality attributes and antioxidant metabolites in 'Sangjudungsi' persimmon fruit stored at 0.5 degrees C and 95% relative humidity over a 3-month period. The treatments caused a reduction in weight loss; in the middle of the cold storage, the soluble solids content was higher with the AVG treatment than with the 1-MCP treatment. Both treatments reduced the incidence and severity of peel blackening and fruit softening, whereas fruit decay was only affected by AVG. The content of total phenolic compounds was lower with AVG than with 1-MCP or in the untreated control during the same period. At the end of cold storage, the AVG treatment resulted in a greater total flavonoid and total antioxidant activity and a higher reduced glutathione level than with 1-MCP or in the untreated control. AVG likely evoked the least physiological and biochemical responses in persimmons, according to the results of a normalized heatmap matrix system. Correlation coefficient networking results showed that 1-MCP and AVG caused differential correlation responses between the fruit quality variables and targeted metabolites during cold storage. Overall, the results indicated that treatment of cold-stored persimmons with 1-MCP and AVG likely reduced the incidence of physiological disorders, although antioxidant metabolites were relatively less affected by both regulators. Win, Nay Myo; Yoo, Jingi; Lwin, Hnin Phyu; Lee, Eun Jin; Kang, In-Kyu; Lee, Jinwook Kyungpook Natl Univ, Dept Hort Sci, Daegu 41566, South Korea; RDA, Apple Res Inst, Natl Inst Hort & Herbal Sci, Gunwi 39000, South Korea; Washington State Univ, Tree Fruit Res Extens Ctr, Wenatchee, WA 98801 USA; Chung Ang Univ, Dept Plant Sci & Technol, Anseong 17546, South Korea; Seoul Natl Univ, Dept Agr Forestry & Bioresources, Coll Agr & Life Sci, Seoul 08826, South Korea; Seoul Natl Univ, Res Inst Agr & Life Sci, Seoul 08826, South Korea 42462548000; 56818324500; 57212822109; 57468998800; 56577308800; 57201971350 JL425@cau.ac.kr; HORTICULTURE ENVIRONMENT AND BIOTECHNOLOGY HORTIC ENVIRON BIOTE 2211-3452 2211-3460 62 6 SCIE HORTICULTURE 2021 2.138 34.7 1.93 2025-07-30 20 21 Ascorbic acid; Decay; Glutathione; Peel blackening; Phenolic compounds; Weight loss CONTROLLED-ATMOSPHERE STORAGE; CHILLING INJURY SYMPTOMS; ETHYLENE RESPONSE GENES; ASCORBIC-ACID CONTENT; MALUS-X-DOMESTICA; OXIDATIVE STRESS; PHYSIOLOGICAL DISORDERS; ROJO BRILLANTE; EMPIRE APPLES; 1-MCP Ascorbic acid; Decay; Glutathione; Peel blackening; Phenolic compounds; Weight loss English 2021 2021-12 10.1007/s13580-021-00360-z 바로가기 바로가기 바로가기 바로가기
Article Morphological and rDNA fluorescence in situ hybridization analyses of chrysanthemum cultivars from Korea Chrysanthemum is a globally important crop associated with a variety of ornamental products including cut flowers, potted plants, and garden varieties, and high demand for such products has facilitated the development of higher-performing varieties that better meet customer and market requirements. However, chrysanthemum breeding is challenging owing to its complex genetic background and limited knowledge of its genetics and ploidy. To provide more information for breeding material identification in chrysanthemum, we performed both morphological and cytogenetic analysis of 11 chrysanthemum cultivars from Korea. Morphological evaluation of the 11 cultivars revealed that cultivar 'Green Diamond' had the tallest plants, 'Orange Pangpang' produced the longest cauline leaves, 'Woonbaek' had the broadest inflorescences, and 'Snow Pop' produced the highest number of ligulate flowers. Cytogenetic investigation suggested that seven of the cultivars (63.6%) were hexaploid (2n = 6x = 54), and the remaining four cultivars (36.4%) were hexaploid-based aneuploids. The cultivars also differed in total chromosome length and in the number 18S rDNA signals, which were located at terminal sites of the short arms. However, all 11 cultivars possessed three pairs of 5S rDNA loci, and those signals were located at interstitial locations of the long arms. These findings will be useful for breeding stock selection, cultivar identification, global communication of new cultivars, and germplasm enhancement. Wang, Yan; Jung, Jae A.; Kim, Won Hee; Lim, Ki-Byung; Hwang, Yoon-Jung Sahmyook Univ, Dept Convergence Sci, Seoul 01795, South Korea; Natl Inst Hort & Herbal Sci, Floriculture Res Div, Wonju 55365, South Korea; Kyungpook Natl Univ, Dept Hort Sci, Daegu 41566, South Korea park, jun yeon/GPX-5293-2022; kim, juhee/HKV-6163-2023 57216450943; 57711123400; 55694081600; 7403175915; 50061210800 hyj@syu.ac.kr; HORTICULTURE ENVIRONMENT AND BIOTECHNOLOGY HORTIC ENVIRON BIOTE 2211-3452 2211-3460 62 6 SCIE HORTICULTURE 2021 2.138 34.7 0.29 2025-07-30 4 4 Aneuploidy; Chrysanthemum; Crop improvement; Hexaploid; Polyploidy 45S RDNA; 5S RDNA; DIVERSITY; FISH; CHROMOSOMES; ASTERACEAE; KARYOTYPE; CLASSIFICATION; LOCALIZATION; ANTHEMIDEAE Aneuploidy; Chrysanthemum; Crop improvement; Hexaploid; Polyploidy English 2021 2021-12 10.1007/s13580-021-00361-y 바로가기 바로가기 바로가기 바로가기
Article Using cytogenetic analysis to identify the genetic diversity in Lilium hansonii (Liliaceae), an endemic species of Ulleung Island, Korea In section Martagon of genus Lilium, L. hansonii is an endemic species of Ulleung island, Korea. Deep golden yellow flowers and two to four whorls of leaves distinguish L. hansonii from other Martagon species. This species is declining in population due to destruction of the wild habitat. Here, we report comprehensive cytogenetic research on 37 individuals of L. hansonii using fluorescence in situ hybridization (FISH). Results of the FISH analysis showed that the distribution of 5S ribosomal DNAs was identical among all individuals of L. hansonii, but numbers of loci of 45S rDNA varied from 13 to 17 and 11 45S rDNA patterns were detected. Based on population level, 45S rDNA loci 13 and 17 were only detected in Seonginbong and Nariryeong, respectively. In addition, certain types of 14 and 15 45S rDNAs loci were found only in Seonginbong and Nariryeong, respectively. In contrast to 45S rDNA, a pair of 5S rDNAs on chromosome 3 was detected in all individuals consistently. The results revealed high genetic diversity in L. hansonii and will help establish a conservation strategy for this species. Choi, Yu-Hyeon; Ramzan, Fahad; Hwang, Yoon-Jung; Younis, Adnan; Kim, Chang-Kil; Lim, Ki-Byung Kyungpook Natl Univ, Dept Hort Sci, Daegu 41566, South Korea; Sahmyook Univ, Dept Life Sci, Seoul 01795, South Korea; Univ Agr Faisalabad, Inst Hort Sci, Faisalabad 38040, Pakistan park, jun yeon/GPX-5293-2022; Younis, Adnan/J-6669-2013 57201334966; 56483068500; 50061210800; 59222988900; 7409880701; 7403175915 kblim@knu.ac.kr; HORTICULTURE ENVIRONMENT AND BIOTECHNOLOGY HORTIC ENVIRON BIOTE 2211-3452 2211-3460 62 5 SCIE HORTICULTURE 2021 2.138 34.7 0.29 2025-07-30 5 4 Chromosome; Fluorescence in situ hybridization; Genetic variation; Lilium hansonii; Species KARYOTYPE ANALYSIS; HYBRIDIZATION; EVOLUTION; EVENTS; LOCI Chromosome; Fluorescence in situ hybridization; Genetic variation; Lilium hansonii; Species English 2021 2021-10 10.1007/s13580-021-00350-1 바로가기 바로가기 바로가기 바로가기
Article Validation of an air temperature gradient using computational fluid dynamics in a semi-open type greenhouse and determination of kimchi cabbage physiological responses to temperature differences Vegetable crops production in the field and changes in physiological aspects of crops during the growing season may be affected by the increased temperatures associated with climate change. The objectives of this research were to evaluate the performance of an air temperature gradient using the computational fluid dynamics (CFD) technique and validation of performance throughout Kimchi cabbage growth and physiological responses to air temperature in a greenhouse temperature gradient (GTG). We simulated temperature differences with CFD in a semi-closed plastic tunnel, which is a GTG. The accuracy of CFD improved by vertical and horizontal temperature profiles was evaluated for the performances of a GTG. The growth of Kimchi cabbage was examined and validated using a temperature gradient within a GTG. Correlation coefficients of measured heights were 1.120, 0.597, and 0.459. Root mean square error was below 0.103, which means the CFD simulation values were highly accurate. The error analysis showed that it was possible to accurately predict temperature gradient changes within a GTG using CFD techniques. CFD results showed an average error of 0.597 degrees C compared to field monitoring results. The maximum temperature difference of the GTG was 5.7 degrees C, suggesting a well-controlled set point (6 degrees C difference between outside conditions and inside conditions of the GTG). On a cloudy day, the GTG set differential temperature (dT) was well maintained, while the accuracy of the GTG's dT was degraded on sunny days because of interference by solar radiation. There was a significant difference in the growth, net photosynthetic rate, transpiration rate, and intercellular CO2 concentration along with temperature differences in the GTG. CFD can simulate temperature gradient distribution in a GTG and predict the temperature difference for equipment with different specifications. These facilities can be used in climate change-related studies, such as assessment of crop production area optimization, crop physiological response to temperature, vulnerability assessment of crop production under increasing temperatures, or extreme weather. Seo, Il-Hwan; Lee, Hee Ju; Wi, Seung Hwan; Lee, Seong-Won; Kim, Sung Kyeom Jeonbuk Natl Univ, Dept Rural Construct Engn, Jeonju 54896, South Korea; Natl Inst Hort & Herbal Sci, Vegetable Res Div, Wonju 55365, South Korea; Kyungpook Natl Univ, Dept Hort Sci, Coll Agr & Life Sci, Daegu 41566, South Korea Lee, Seong-Won/KIH-5115-2024; SEO, ILHWAN/JVZ-7567-2024; Kim, Sung Kyeom/AAD-9230-2019 15078058600; 59106640900; 58607882100; 57224862768; 50262290200 skkim76@knu.ac.kr; HORTICULTURE ENVIRONMENT AND BIOTECHNOLOGY HORTIC ENVIRON BIOTE 2211-3452 2211-3460 62 5 SCIE HORTICULTURE 2021 2.138 34.7 1.16 2025-07-30 11 12 Climate change; Computational fluid dynamics; Extreme weather; Physiological responses; Temperature gradient greenhouse CHANGE ELEVATED CO2; CLIMATE-CHANGE; CHINESE-CABBAGE; WATER-DEFICIT; PHOTOSYNTHETIC ACCLIMATION; CARBON-DIOXIDE; PLANT-GROWTH; GRAPEVINE; YIELD; CFD Climate change; Computational fluid dynamics; Extreme weather; Physiological responses; Temperature gradient greenhouse English 2021 2021-10 10.1007/s13580-021-00378-3 바로가기 바로가기 바로가기 바로가기
Article A large-scale metagenomic study for enzyme profiles using the focused identification of the NGS-based definitive enzyme research (FINDER) strategy Excavating the molecular details of many diverse enzymes from metagenomes remains challenging in agriculture, food, health, and environmental fields. We present a versatile method that accelerates metabolic enzyme discovery for highly selective gene capture in metagenomes using next-generation sequencing. Culture-independent enzyme mining of environmental DNA is based on a set of short identifying degenerate sequences specific for a wide range of enzyme superfamilies, followed by multiplexed DNA barcode sequencing. A strategy of 'focused identification of next-generation sequencing-based definitive enzyme research' enabled us to generate targeted enzyme datasets from metagenomes, resulting in minimal hands-on obtention of high-throughput biological diversity and potential function profiles, without being time-consuming. This method also provided a targeted inventory of predicted proteins and molecular features of metabolic activities from several metagenomic samples. We suggest that the efficiency and sensitivity of this method will accelerate the decryption of microbial diversity and the signature of proteins and their metabolism from environmental samples. Sung, Jae-Yoon; Lee, Yong-Jik; Cho, Yong-Joon; Shin, Myeong-Na; Lee, Sang-Jae; Lee, Han-Seung; Koh, Hong; Bae, Jin-Woo; Shin, Jae-Ho; Kim, Hyun Jung; Lee, Dong-Woo Yonsei Univ, Dept Biotechnol, Seoul 03722, South Korea; Seowon Univ, Dept Biocosmet, Chungju, South Korea; Seoul Natl Univ, Dept Biol Sci, Seoul, South Korea; Seoul Natl Univ, Res Inst Basic Sci, Seoul, South Korea; RDA, NICS, Dept Cent Area Crop Sci, Suwon, South Korea; Silla Univ, Major Food Biotechnol, Busan, South Korea; Yonsei Univ, Dept Pediat, Seoul, South Korea; Kyung Hee Univ, Dept Biol, Seoul, South Korea; Kyungpook Natl Univ, Dept Appl Biosci, Daegu, South Korea; Univ Texas Austin, Dept Biomed Engn, Austin, TX 02115 USA Lee, HanSeung/E-9087-2013; Kim, Hyun Jung/V-7593-2017; Lee, Jeong-Hoon/Q-1055-2018; Bae, Jin-Woo/S-1955-2017; Lee, Sang-Jae/IQU-9591-2023; Kim, Hyun Jung/GQP-3241-2022 57211241011; 57209343349; 55472204400; 57226530043; 55716365300; 54682047600; 35789948700; 8052688000; 57224125922; 57037642400; 57195068659 hyunjung.kim@utexas.edu;leehicam@yonsei.ac.kr; BIOTECHNOLOGY AND BIOENGINEERING BIOTECHNOL BIOENG 0006-3592 1097-0290 118 11 SCIE BIOTECHNOLOGY & APPLIED MICROBIOLOGY 2021 4.395 34.9 0.46 2025-07-30 8 8 enzyme profiling; FINDER; metabolic activity; metagenome; next-generation sequencing SURFACE DISPLAY; ACCURATE; EVOLUTION; ALIGNMENT; GENES enzyme profiling; FINDER; metabolic activity; metagenome; next-generation sequencing DNA Barcoding, Taxonomic; Enzymes; High-Throughput Nucleotide Sequencing; Metagenomics; Agricultural robots; DNA sequences; Gene encoding; Metabolism; environmental DNA; enzyme; Degenerate sequences; Environmental fields; Environmental sample; Enzyme superfamilies; Metabolic activity; Microbial diversity; Next-generation sequencing; Potential function; amplicon; Article; DNA barcoding; DNA sequence; enzyme analysis; high throughput sequencing; metagenome; metagenomics; microbial diversity; nonhuman; protein fingerprinting; species diversity; DNA barcoding; genetics; Enzymes English 2021 2021-11 10.1002/bit.27904 바로가기 바로가기 바로가기 바로가기
Article Nucleocapsid and Spike Proteins of SARS-CoV-2 Drive Neutrophil Extracellular Trap Formation Patients with severe coronavirus disease 2019 (COVID-19) demonstrate dysregulated immune responses including exacerbated neutrophil functions. Massive neutrophil infiltrations accompanying neutrophil extracellular trap (NET) formations are also observed in patients with severe COVID-19. However, the mechanism underlying severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-induced NET formation has not yet been elucidated. Here we show that 2 viral proteins encoded by SARS- CoV-2, the nucleocapsid protein and the whole spike protein, induce NET formation from neutrophils. NET formation was ROSindependent and was completely inhibited by the spleen tyrosine kinase inhibition. The inhibition of p38 MAPK, protein kinase C, and JNK signaling pathways also inhibited viral protein-induced NET formation. Our findings demonstrate one method by which SARSCoV-2 evades innate immunity and provide a potential target for therapeutics to treat patients with severe COVID-19. Youn, Young-Jin; Lee, Yu-Bin; Kim, Sun-Hwa; Jin, Hee Kyung; Bae, Jae-sung; Hong, Chang-Won Kyungpook Natl Univ, Sch Med, Dept Physiol, 680 Gukchaebosang Ro, Daegu 41944, South Korea; Kyungpook Natl Univ, Coll Vet Med, Dept Lab Anim Med, Daegu 41944, South Korea; Kyungpook Natl Univ, Sch Med, KNU Alzheimers Dis Res Inst, Daege 41566, South Korea Kim, Young/T-8521-2019; Youn, Young Jin/KQU-0973-2024; Hong, Chang-Won/L-1272-2015; Bae, Jae-sung/AAM-8663-2021 57195676656; 57219808197; 57219815385; 8088145800; 35209510400; 55567018400 cwhong@knu.ac.kr; IMMUNE NETWORK IMMUNE NETW 1598-2629 2092-6685 21 2 SCIE IMMUNOLOGY 2021 5.851 34.9 1.26 2025-07-30 21 18 Severe acute respiratory syndrome coronavirus 2; Neutrophils; Neutrophil extracellular traps; Viral protein; C-type lectin receptor; Spleen tyrosine kinase LECTIN RECEPTORS; SYK; RECOGNITION; KINASE C-type lectin receptor; Neutrophil extracellular traps; Neutrophils; Severe acute respiratory syndrome coronavirus 2; Spleen tyrosine kinase; Viral protein mitogen activated protein kinase p38; protein kinase C; reactive oxygen metabolite; virus spike protein; Article; controlled study; extracellular trap; human; human cell; immune evasion; innate immunity; JNK signaling; neutrophil chemotaxis; nonhuman; Severe acute respiratory syndrome coronavirus 2; virus nucleocapsid English 2021 2021-04 10.4110/in.2021.21.e16 바로가기 바로가기 바로가기 바로가기
Article Correction of secondary unilateral cleft lip nasal deformity in adults using lower lateral cartilage repositioning, columellar strut, and onlay cartilage graft on the nasal tip with open rhinoplasty combined with reverse-U incision A rhinoplasty technique involving lower lateral cartilage (LLC) repositioning and grafting of ear cartilage allows for nasal lengthening and nasal tip mobility. For better esthetic outcomes in patients with cleft lip nasal deformity (CLND), we combined cosmetic nasal tip plasty with standard techniques. We performed open rhinoplasty combined with reverse-U incision and V-Y plasty in 62 patients with secondary unilateral CLND from October 2013 to June 2018. Both LLCs were isolated, repositioned, approximated medially, and advanced with a Medpor strut, followed by tip suture technique. To further project and enhance the nasal tip and columella, application of ear cartilage onlay graft was used. As adjunctive procedures, septoplasty or osteotomy was carried out for correction of septal or nasal bone deviations, respectively. Photogrammetric evaluations of patients and statistical analyses were performed. Average age at operation was 23.5 years (range: 18-42 years). Of the 62 patients, 15 underwent dorsal augmentation with silicone implant. Two-layer conchal cartilage onlay grafting was performed to manage tip height. Outcomes in 34 patients were analyzed with pre- and postoperative photography. Nasal tip projection increased, alar base width index decreased, and alar and columellar symmetry significantly improved. No Medpor implant exposure or other adverse outcomes occurred. The proposed technique is effective for correcting secondary unilateral CLND and achieving a satisfying nasal appearance in adults. (C) 2020 Published by Elsevier Ltd on behalf of British Association of Plastic, Reconstructive and Aesthetic Surgeons. Cho, Byung Chae; Lee, Jeong Woo; Lee, Joon Seok; Lee, Jong Ho; Ryu, Jeong Yeop; Tian, Lulu; Choi, Kang Young; Yang, Jung Dug; Chung, Ho Yun Kyungpook Natl Univ, Sch Med, Dept Plast & Reconstruct Surg, 130 Dongdeok Ro, Daegu 41944, South Korea Yang, Jung/R-7806-2019; Ryu, Jeong Yeop/GLQ-9419-2022; Lee, Woo Hyuk/HTT-3694-2023; LEE, JIN/Q-3108-2018 55662871100; 55892173700; 56496041000; 57212661146; 56366349400; 57205625623; 57203745682; 55171704700; 7404007181 bccho@knu.ac.kr;jeongwoo@daum.net;leejspo@naver.com;clerk0823@naver.com;rjyflying@naver.com;2013467033@knu.ac.kr;kychoi@knu.ac.kr;lambyang@knu.ac.kr;hy-chung@knu.ac.kr; JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY J PLAST RECONSTR AES 1748-6815 1878-0539 74 5 SCIE SURGERY 2021 3.022 35.0 2.32 2025-07-30 18 16 Cleft lip nasal deformity; Lower lateral cartilage; Columellar strut; Onlay graft SEPTAL EXTENSION GRAFT; PLASTY; NOSE; REPAIR Cleft lip nasal deformity; Columellar strut; Lower lateral cartilage; Onlay graft Adolescent; Adult; Cleft Lip; Ear Cartilage; Esthetics; Female; Humans; Male; Nasal Cartilages; Nose; Osteotomy; Rhinoplasty; epinephrine; lidocaine; adult; anatomical variation; Article; cartilage graft; cleft lip nose; clinical article; clinical effectiveness; ear cartilage; female; follow up; height; human; length; lip reconstruction; male; nasal bone; nose cartilage; nose malformation; nose mucosa; nose surgery; open surgery; osteotomy; patient satisfaction; photogrammetry; photography; postoperative period; preoperative evaluation; priority journal; rhinoplasty; septoplasty; sinus floor augmentation; size; skin incision; surgical technique; suture technique; unilateral cleft lip; young adult; adolescent; cleft lip; esthetics; nose; procedures; transplantation English 2021 2021-05 10.1016/j.bjps.2020.10.060 바로가기 바로가기 바로가기 바로가기
Article Inhibitory effects of cudratricusxanthone O on particulate matter-induced pulmonary injury Particulate matter 2.5 (PM2.5), aerodynamic diameter <= 2.5 mu m, is the primary air pollutant that plays the key role for lung injury resulted from the loss of vascular barrier integrity. Cudratricusxanthone O (CTXO) is a novel xanthone compound isolated from the root of Cudrania tricuspidata Bureau. Here, we investigated the beneficial effects of CTXO against PM-induced lung endothelial cell (EC) barrier disruption and pulmonary inflammation. Permeability, leukocyte migration, activation of proinflammatory proteins, generation of reactive oxygen species (ROS), and histology were examined in PM2.5-treated ECs and mice. CTXO significantly scavenged PM2.5-induced ROS and inhibited the ROS-induced activation of p38 mitogen-activated protein kinase (MAPK). Concurrently, CTXO activated Akt, which helped maintain endothelial integrity. Furthermore, CTXO reduced vascular protein leakage, leukocyte infiltration, and proinflammatory cytokine release in the bronchoalveolar lavage fluid in PM-induced lung tissues. These results indicated that CTXO may exhibit protective effects against PM-induced inflammatory lung injury and vascular hyperpermeability. Lee, Wonhwa; Ku, Sae-Kwang; Kim, Tae In; Kim, Eun-Nam; Park, Eui Kyun; Jeong, Gil-Saeng; Bae, Jong-Sup Korea Res Inst Biosci & Biotechnol, Aging Res Ctr, Deajeon, South Korea; Kyungpook Natl Univ, Coll Pharm, Res Inst Pharmaceut Sci, CMRI,BK21 Plus KNU Multiom Based Creat Drug Res T, Daegu, South Korea; Daegu Haany Univ, Coll Korean Med, Dept Histol & Anat, Gyongsan, South Korea; Keimyung Univ, Coll Pharm, Daegu, South Korea; Korea Inst Oriental Med, Korean Med KM Applicat Ctr, Daegu, South Korea; Kyungpook Natl Univ, Sch Dent, Dept Pathol & Regenerat Med, Daegu, South Korea ; Bae, Jong-Sup/AAU-9724-2020; Lee, Wonhwa/GLQ-6506-2022 50161632800; 7006331005; 57210557554; 57201655294; 37071072400; 57204396456; 16021543200 baejs@knu.ac.kr;gsjeong@kmu.ac.kr; INTERNATIONAL JOURNAL OF ENVIRONMENTAL HEALTH RESEARCH INT J ENVIRON HEAL R 0960-3123 1369-1619 31 3 SCIE ENVIRONMENTAL SCIENCES;PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH 2021 4.477 35.0 0.14 2025-07-30 8 3 Cudratricusxanthone O; particulate matter; vascular permeability; Akt LUNG INJURY; ULTRAFINE PARTICLES; OXIDATIVE STRESS; PM2.5 EXPOSURE; CELLS; CONSTITUENTS; INFLAMMATION; POLLUTION; HYPERRESPONSIVENESS; TRANSCRIPTION Akt; Cudratricusxanthone O; particulate matter; vascular permeability Air Pollutants; Animals; Endothelial Cells; Lung Injury; Male; Mice; Mice, Inbred BALB C; Moraceae; Particulate Matter; Pneumonia; Protective Agents; Xanthones; Maclura tricuspidata; antiinflammatory agent; antioxidant; cudratricusxanthone O; herbaceous agent; interleukin 6; mitogen activated protein kinase p38; protective agent; protein kinase B; reactive oxygen metabolite; tumor necrosis factor; unclassified drug; xanthone derivative; protective agent; xanthone derivative; aerodynamics; atmospheric pollution; cell component; histology; inhibitor; injury; protein; reactive oxygen species; respiratory disease; animal cell; animal experiment; animal model; animal tissue; antiinflammatory activity; antioxidant activity; Article; blood vessel permeability; capillary endothelial cell; cell disruption; cell infiltration; cell membrane permeability; controlled study; cytokine release; drug efficacy; drug mechanism; endothelial dysfunction; enzyme activation; histopathology; inflammation; leukocyte migration; lung alveolus cell; lung capillary; lung injury; lung lavage; lung microvascular endothelial cell; lung parenchyma; male; mouse; nonhuman; oxidative stress; PM2.5 exposure; pneumonia; protein phosphorylation; structure activity relation; adverse event; air pollutant; animal; Bagg albino mouse; chemistry; drug effect; endothelium cell; lung injury; Moraceae; particulate matter; pneumonia English 2021 2021-04-03 10.1080/09603123.2019.1652252 바로가기 바로가기 바로가기 바로가기
Article PLF-VINS: Real-Time Monocular Visual-Inertial SLAM With Point-Line Fusion and Parallel-Line Fusion This letter presents a real-time monocular visual-inertial simultaneous localization and mapping with point-line fusion and parallel-line fusion. The corner and line features provide plenty of information about object structures. In the 2D image plane, such corner and line features have a positional similarity. The corner feature represents an endpoint of an object's edge, and the line feature represents a straight edge. We propose two novel methods for fusing corner and line features to improve localization accuracy. The first method is for fusing corner and line features. Using the positional similarity of corner and line features, we search the relationship between two features by utilizing the proposed point-line coupled residual. The second method is for fusing parallel 3D lines. First, we search for line features clustered based on a vanishing point. Then, the outliers in the parallel 3D lines are removed using the proposed consistency check during the multi-view line clustering. Finally, the parallel 3D lines are used in the proposed parallel 3D line residual. Experimental results show that real-time localization accuracy is improved when two proposed residuals are integrated with the sliding-window optimization. The proposed PLF-VINS is compared with other state-of-the-art algorithms using the public EuRoC dataset. Lee, Junesuk; Park, Soon-Yong Kyungpook Natl Univ, Sch Elect & Elect Engn, Daegu 41566, South Korea ; Park, Soon-Yong/HGV-2374-2022 57210786619; 7501834063 ljs2352@gmail.com;sypark@knu.ac.kr; IEEE ROBOTICS AND AUTOMATION LETTERS IEEE ROBOT AUTOM LET 2377-3766 6 4 SCIE ROBOTICS 2021 4.321 35.0 3.93 2025-07-30 64 71 Simultaneous localization and mapping; sensor fusion; monocular visual-inertial SLAM; localization KALMAN FILTER; ODOMETRY; ROBUST localization; monocular visual-inertial SLAM; sensor fusion; Simultaneous localization and mapping Consistency checks; Localization accuracy; Object structure; Real-time localization; Simultaneous localization and mapping; Sliding Window; State-of-the-art algorithms; Vanishing point; Agricultural robots English 2021 2021-10 10.1109/lra.2021.3095518 바로가기 바로가기 바로가기 바로가기
Article Spiritual leadership and work-family conflict: mediating effects of employee well-being Purpose This study examines how employee well-being, in combination with spiritual leadership, helps mitigate the negative effects of work-family conflict. Design/methodology/approach This study followed an explanatory research design to explain the relationship between spiritual leadership and work-family conflict. The approach was based on a cross-sectional survey of 278 workers from diverse industries and functional roles in South Korea's manufacturing and service sectors. Structural equation modeling and hierarchical regression analysis were used to test hypothesized relationships. Findings Results confirmed that spiritual leadership and employee well-being inversely influenced work-family conflict, in terms of work-to-family and family-to-work role interference. Furthermore, employee well-being fully mediated both of these relationships. Originality/value This study expands the scope of our current understanding of how employee well-being is an effective mechanism in helping employees cope with work-family role conflict. Moreover, the study demonstrates the role that leadership practices, beyond the narrow interpretation of perceived supervisor support, play in helping employees cope with role conflict. Finally, this study enhances the field of workplace spirituality by examining the influence of spiritual leadership on employees' spiritual well-being and work-family conflict, which has not been currently addressed in the workplace spirituality field. Hunsaker, William D. Kyungpook Natl Univ, Sch Business Adm, Daegu, South Korea Hunsaker, William/E-9696-2017 55974245100 hunsaker@knu.ac.kr; PERSONNEL REVIEW PERS REV 0048-3486 1758-6933 50 1 SSCI INDUSTRIAL RELATIONS & LABOR;MANAGEMENT;PSYCHOLOGY, APPLIED 2021 3.228 35.0 1.34 2025-07-30 28 26 Quantitative; Supervisor support; Work-family conflict; Workplace spirituality; Employee well-being; Spiritual leadership; Family-friendly culture TRANSFORMATIONAL LEADERSHIP; WORKPLACE SPIRITUALITY; SUPERVISOR SUPPORT; SOCIAL SUPPORT; ENVIRONMENTS; VALIDATION; RESOURCES; BEHAVIOR; BALANCE; MODEL Employee well-being; Family-friendly culture; Quantitative; Spiritual leadership; Supervisor support; Workplace spirituality; Work–family conflict English 2021 2021-01-13 10.1108/pr-04-2019-0143 바로가기 바로가기 바로가기 바로가기
Article U-Pb Age Dating and Geochemistry of Soft-Sediment Deformation Structure-Bearing Late Cretaceous Volcano-Sedimentary Basins in the SW Korean Peninsula and Their Tectonic Implications Cretaceous volcano-sedimentary basins and successions in the Korean Peninsula are located along NE-SW- and NNE-SSW-trending sinistral strike-slip fault systems. Soft-sediment deformation structures (SSDS) of lacustrine sedimentary strata occur in the Wido, Buan, and Haenam areas of the southwestern Korean Peninsula. In this study, systematic geological, geochronological, and geochemical investigations of the volcanic-sedimentary successions were conducted to constrain the origin and timing of SSDS-bearing lacustrine strata. The SSDS-bearing strata is conformably underlain and overlain by volcanic rocks, and it contains much volcaniclastic sediment and is interbedded with tuffs. The studied SSDSs were interpreted to have formed by ground shaking during syndepositional earthquakes. U-Pb zircon ages of volcanic and volcaniclastic rocks within the studied volcano-sedimentary successions were ca. 87-84 Ma, indicating that active volcanism was concurrent with lacustrine sedimentation. Geochemical characteristics indicate that these mostly rhyolitic rocks are similar to subduction-related calc-alkaline volcanic rocks from an active continental margin. This suggests that the SSDSs in the study area were formed by earthquakes related to proximal volcanic activity due to the oblique subduction of the Paleo-Pacific Plate during the Late Cretaceous. Ko, Kyoungtae; Kim, Sungwon; Gihm, Yongsik Korea Inst Geosci & Mineral Resources, Geol Div, 124 Gwahang No, Daejeon 34132, South Korea; Kyungpook Natl Univ, Sch Earth Syst Sci, Daegu 41566, South Korea 56652511400; 50561745800; 56025805300 kkt@kigam.re.kr;sungwon@kigam.re.kr;naress@knu.ac.kr; MINERALS MINERALS-BASEL 2075-163X 11 5 SCIE GEOCHEMISTRY & GEOPHYSICS;MINERALOGY;MINING & MINERAL PROCESSING 2021 2.818 35.0 0.19 2025-07-30 2 2 late Cretaceous; soft sediment deformation; Korean Peninsula; basin; volcanic activity UHANGRI-FORMATION; SOUTHWEST KOREA; GYEONGSANG BASIN; WIDO VOLCANICS; EVOLUTION; DEPOSITS; ENVIRONMENTS; OCCURRENCES; FACIES; SYSTEM Basin; Korean Peninsula; Late Cretaceous; Soft sediment deformation; Volcanic activity English 2021 2021-05 10.3390/min11050520 바로가기 바로가기 바로가기 바로가기
Article Biocompatibility of Ni-Cr alloys, with the same composition, prepared by two new digital manufacturing techniques This study evaluated the in vitro biocompatibility of nickel-chromium (Ni-Cr) alloys produced via three different manufacturing techniques (casting, selective laser melting [SLM], and soft milling [SM]) from a single alloy with the same elemental composition. The microstructure, ion release, and cell viability of the alloys were studied. The Ni-based gamma phase was identified for the three alloys. A segregation of the Cr and molybdenum (Mo) was observed in the cast alloy. The SLM and SM alloys exhibited a more homogeneous elemental dispersion and a finer grain formation than the cast one. Extensive porosity as well as (Mo,Cr)C carbide were generated in the SM alloy. The SLM alloy showed the lowest release of Ni ion, followed by the SM alloy (p < 0.001) and then the cast alloy (p < 0.05). The SLM alloy also exhibited the greatest density and viability of L929 mouse fibroblasts, followed by the SM alloy (p < 0.05) and lastly the cast alloy (p < 0.001). It was concluded that the SLM alloy had superior biocompatibility, cell viability of the SM alloy being slightly less but still greater than that of cast alloy. Yun, Chang-Su; Hanawa, Takao; Hong, Min-Ho; Min, Bong Ki; Kwon, Tae-Yub Kyungpook Natl Univ, Grad Sch, Dept Dent Sci, Daegu, South Korea; Tokyo Med & Dent Univ, Inst Biomat & Bioengn, Dept Metall Mat, Tokyo, Japan; Catholic Univ Pusan, Coll Hlth Sci, Dept Dent Lab Sci, Busan, South Korea; Yeungnam Univ, Ctr Res Facil, Gyongsan, South Korea; Kyungpook Natl Univ, Sch Dent, Dept Dent Biomat, Daegu, South Korea; Kyungpook Natl Univ, Inst Biomat Res & Dev, Daegu, South Korea; 57 Oryundae Ro, Busan 46252, South Korea; 2177 Dalgubeol Daem, Daegu 41940, South Korea 57241370900; 55532801000; 57192705343; 57211058922; 7202206084 mhhong@cup.ac.kr;tykwon@knu.ac.kr; MATERIALS LETTERS MATER LETT 0167-577X 1873-4979 305 SCIE MATERIALS SCIENCE, MULTIDISCIPLINARY;PHYSICS, APPLIED 2021 3.574 35.1 0.88 2025-07-30 12 13 Ni-Cr alloy; Selective laser melting; Soft milling; Microstructure; Biomaterials Biomaterials; Microstructure; Ni–Cr alloy; Selective laser melting; Soft milling Biocompatibility; Carbides; Cell culture; Chromium compounds; Melting; Microstructure; Milling (machining); Molybdenum alloys; Selective laser melting; Cast alloys; Cell viability; Digital manufacturing; In-vitro; Manufacturing techniques; Melting alloys; Nickel-Chromium alloys; Selective laser melting; Soft milling; Vitro biocompatibilities; Chromium alloys English 2021 2021-12-15 10.1016/j.matlet.2021.130761 바로가기 바로가기 바로가기 바로가기
Article Loading-direction dependence of fatigue behavior of rolled Mg alloy containing {10-12} twins This study demonstrates that unlike a twin-free rolled Mg alloy, a {10-12}-twin-containing rolled Mg alloy exhibits considerably different low-cycle fatigue characteristics depending on the loading direction on the rolling plane. In situ electron backscatter diffraction results reveal that the contribution of the initial {10-12} twins to strain accommodation during cyclic deformation in different loading directions follows the order of rolling direction (RD) > 45 degrees to the RD (45RD) > transverse direction (TD). This result is attributed to the angle difference between the RD-oriented twinned region and the applied loading direction. An increase in the relative twinning (or detwinning) activity causes a decrease in the mean stress. Consequently, the fatigue life of the pre-twinned alloy varies with the loading direction and follows the order of RD > 45RD > TD. (c) 2021 Elsevier B.V. All rights reserved. Lee, Jeong Hun; Kim, Ye Jin; Park, Sung Hyuk Korea Inst Ind Technol, Adv Forming Proc R&D Grp, Ulsan 44413, South Korea; Kyungpook Natl Univ, Sch Mat Sci & Engn, Daegu 41566, South Korea Lee, Jeong Hun/KFS-8195-2024; Park, Sung-Hyuk/AAE-6726-2022 54785958500; 59052467200; 54786002500 sh.park@knu.ac.kr; MATERIALS LETTERS MATER LETT 0167-577X 1873-4979 295 SCIE MATERIALS SCIENCE, MULTIDISCIPLINARY;PHYSICS, APPLIED 2021 3.574 35.1 0.44 2025-07-30 7 7 Magnesium; {10-12} twin; Low-cycle fatigue; Loading direction; In situ EBSD DEFORMATION-BEHAVIOR; MAGNESIUM ALLOYS In situ EBSD; Loading direction; Low-cycle fatigue; Magnesium; {1 0 −1 2} twin Magnesium; Magnesium alloys; Rolling; Stress analysis; Direction dependence; Fatigue behaviour; Fatigue characteristics; In situ EBSD; Loading direction; Low cycle fatigues; Mg alloy; Rolling direction; Twin-free; {1 0 −1 2} twin; Fatigue of materials English 2021 2021-07-15 10.1016/j.matlet.2021.129835 바로가기 바로가기 바로가기 바로가기
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KeywordsPlus (SCOPUS) SCOPUS에서 자동으로 추출하거나 추가한 색인 키워드입니다.
Language 논문이 작성된 언어입니다. 대부분 English이며, 그 외 다양한 언어로 작성된 논문이 포함될 수 있습니다.
Publication Year 논문이 출판된 연도입니다.
Publication Date 논문의 정확한 출판 날짜입니다 (년-월-일 형식).
DOI Digital Object Identifier. 디지털 객체 식별자로, 논문을 고유하게 식별하는 영구적인 식별번호입니다. 이를 통해 논문의 온라인 위치를 찾을 수 있습니다.