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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Article | Exploring Volatility Properties of Discrete Secondary Organic Aerosol Constituents of α-Pinene and Polycyclic Aromatic Hydrocarbons | Limited experimental data are available on the volatility parameters of saturation vapor pressure, vaporization enthalpy, and melting temperature of secondary organic aerosol (SOA) constituents. In this study, we aimed to determine the volatility of individual components of typical biogenic and anthropogenic SOA. The volatility profiles of four synthesized and two commercial SOA constituents were generated using a thermal denuder coupled with a scanning particle sizer. For the volatility measurement, four constituents of alpha-pinene SOA were synthesized in the laboratory because of the lack of commercial reagents. For each of the SOA species, a volatility profile was measured by changing the thermal denuder temperature below its melting point measured using thermal gravimetric analysis and differential scanning calorimetry. Saturation pressure (P-sat(0)) and vaporization enthalpy (del H-v) at 25 degrees C of the SOA constituents were determined by applying the integrated volume method to the measured volatility profiles. The determined P-sat(0) values of 3-methylbutane-1,2,3-tricarboxylic acid (3-MBTCA), terpenylic acid, diaterpenylic acid acetate (DTAA), sodium-(1R,2R,3S,5R)-2-hydroxy-2,6,6-trimethylbicyclo[3.1.1]heptan-3-yl sulfate (Na-2-OH-2,6,6-TMBHS), 1,2,4,5-benzenetetracarboxylic acid (1,2,4,5-B4CA), and 1,2,4-benzenetricarboxylic acid (1,2,4-B3CA) were 3.4 +/- 0.6 x 10(-5), 1.7 +/- 0.3 x 10(-4), 1.8 +/- 0.2 x 10(-5), 3.4 +/- 0.4 x 10(-5), 7.7 +/- 0.7 x 10(-5), and 2.1 +/- 0.3 x 10(-6) Pa, respectively. The estimated values of del H-v for 3-MBTCA, terpenylic acid, DTAA, Na-2-OH-2,6,6-TMBHS, 1,2,4,5-B4CA, and 1,2,4-B3CA were 128.4 +/- 4.7, 88.4 +/- 3.5 135.4 +/- 3.7, 38.4 +/- 1.7, 42.8 +/- 2.1, and 108.1 +/- 4.1 kJ mol(-1), respectively. These data will improve the knowledge of the formation and fate of SOA. | Bin Babar, Zaeem; Ashraf, Fawad; Park, Jun-Hyun; Pham Duy Quang Dao; Cho, Chan Sik; Lim, Ho-Jin | Kyungpook Natl Univ, Dept Environm Engn, Daegu 41566, South Korea; Univ Punjab, Inst Energy & Environm Engn, Lahore 54590, Pakistan; COMSATS Inst Informat Technol, Dept Chem Engn, Lahore 54000, Pakistan; Kyungpook Natl Univ, Dept Appl Chem, Daegu 41566, South Korea | Ashraf, Fawad/MHR-0219-2025; Dao, P. D. Quang/AAR-9880-2021; Bin Babar, Zaeem/T-1026-2019 | 56106569100; 57190007797; 57192248319; 57194217171; 7403100019; 56883100200 | hjlim@knu.ac.kr; | ACS EARTH AND SPACE CHEMISTRY | ACS EARTH SPACE CHEM | 2472-3452 | 4 | 12 | SCIE | CHEMISTRY, MULTIDISCIPLINARY;GEOCHEMISTRY & GEOPHYSICS | 2020 | 3.475 | 35.8 | 0.31 | 2025-06-25 | 4 | 4 | thermal denuder; volatility; saturation pressure; enthalpy of vaporization; melting temperature; synthesized secondary organic aerosol (SOA); thermal gravimetric analysis; differential scanning calorimetry | PURE-COMPONENT PROPERTIES; PRESSURE ESTIMATION METHODS; DIATERPENYLIC ACID ACETATE; EQUILIBRATION TIME SCALES; PHASE OH OXIDATION; VAPOR-PRESSURE; ATMOSPHERIC AEROSOLS; BOILING-POINT; AIR-QUALITY; 3-METHYL-1,2,3-BUTANETRICARBOXYLIC ACID | differential scanning calorimetry; enthalpy of vaporization; melting temperature; saturation pressure; synthesized secondary organic aerosol (SOA); thermal denuder; thermal gravimetric analysis; volatility | aerosol composition; calorimetry; enthalpy; formation mechanism; melting; P-T conditions; PAH; saturation; thermogravimetry; vaporization | English | 2020 | 2020-12-17 | 10.1021/acsearthspacechem.0c00210 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Petrogenesis of subduction-related lavas from the southern Tonga arc | We present new whole-rock geochemical data for volcanic rocks dredged from active submarine volcanoes TA15, TA16, and TA19 that mark the southern part of the Tonga Arc near Ata island. The lava samples show a wide range of compositions from basalt to dacite within the low-K tholeiitic series, and geochemical data indicate fractional crystallization of olivine, orthopyroxene, clinopyroxene, and plagioclase. The origin of magmas in the southern Tonga Arc can be explained by the mixing of three components: a depleted mantle wedge, a melt derived from the partial melting of subducted pelagic sediments (PS) and sediments of the subducted Louisville Seamount Chain (LSC), and a fluid produced during subduction by the dehydration of altered oceanic crust (AOC). Our geochemical modeling suggests that mafic magmas in the study area can be generated by 10%-25% partial melting of a depleted mantle that had been metasomatized by similar to 1% AOC fluids as well as similar to 1% melts derived from a 40:60 mixture of LSC and PS sedimentary components. On the other hand, volcanoes V, U, and Monowai, located farther south near the present LSC-Tonga Trench intersection, can be generated by 15%-25% partial melting of a depleted mantle that had been metasomatized by similar to 0.5% AOC fluids as well as similar to 1.5% sediment-derived melts (a 90:10 mixture of LSC and PS). These results are consistent with previous proposals that the influence of the LSC-derived components was stronger in the southerly volcanoes V, U, and Monowai than in the volcanoes near Ata. | Myeong, Bora; Kim, Jonguk; Kim, Jung Hoon; Jang, Yun Deuk | KIOST, Deep Sea & Seabed Mineral Resources Res Ctr, Busan 49111, South Korea; Kyungpook Natl Univ, Dept Geol, Daegu 41566, South Korea; Div Environm Policy, Andong 36759, South Korea | Kim, Jonguk/L-4464-2019 | 57201401851; 55719992100; 57204884378; 7201869003 | jukim@kiost.ac.kr; | JOURNAL OF ASIAN EARTH SCIENCES | J ASIAN EARTH SCI | 1367-9120 | 1878-5786 | 188 | SCIE | GEOSCIENCES, MULTIDISCIPLINARY | 2020 | 3.449 | 35.8 | 0.41 | 2025-06-25 | 4 | 4 | Southern Tonga Arc; Mantle source; Subduction component; Louisville Seamount Chain; Pelagic sediment; Altered oceanic crust | TRACE-ELEMENT; ISLAND-ARC; BACK-ARC; KERMADEC ARC; U-SERIES; MANTLE DYNAMICS; MAGMA GENESIS; HIGH-PRESSURE; HAVRE TROUGH; ISOTOPE DATA | Altered oceanic crust; Louisville Seamount Chain; Mantle source; Pelagic sediment; Southern Tonga Arc; Subduction component | Louisville Seamount Chain; Pacific Ocean; fractional crystallization; lava flow; mantle source; partial melting; pelagic deposit; petrogenesis; subduction; submarine volcano; volcanic rock | English | 2020 | 2020-02 | 10.1016/j.jseaes.2019.104089 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Epidemiology and risk factors of coccyx fracture: A study using national claim database in South Korea | Introduction: Coccyx fracture usually is a low-energy trauma caused by a backward fall onto a slippery floor of ice. The exact epidemiology of the coccyx fracture is not known. Moreover, the effects of seasonality and weather on the fracture incidence have not been reported. The purpose of this study was to evaluate the annual incidence, gender-preponderance, age-distribution, seasonal variation and climatic risk factors of the coccyx fracture. Methods: We identified coccyx fractures, which occurred in South Korea from 2010 to 2018, using nationwide data of Korean Health Insurance Review and Assessment Service (HIRA). International Classification of Diseases-10th Revision (ICD-10) code 5322 was used for the identification. Annual incidence of the coccyx fracture was calculated, and the fractures were correlated with gender, age, month of diagnosis and climatic factors. Results: A total of 238,906 patients were diagnosed with coccyx fracture with an average of 26,545 patients at year. Male to female ratio was 1:2.6. The annual incidence of coccyx fracture was 119.75/100,000 persons in 2018; 33.44/100,000 in male and 86.30/100,000 in female. The incidence rate was the highest at puberty (age of 10-14 years) in male, and at menopause (age of 50-54 years) in female. The incidence was frequent in winter followed by summer. The incidence of coccyx fracture was negatively correlated with the temperature (Pearson correlation factor= -0.67, P<0.01) in winter, while it was positively correlated with the temperature in summer (Pearson correlation coefficient = 0.66, p<0.01). In generalized linear model, old age, female gender, recent year, summer and winter, low temperature and high amount of precipitation appeared as risk factors for coccyx fracture. Conclusions: The epidemiologic patterns of coccyx fracture were comparable to other osteoporotic fractures. Findings of our study can be used for epidemiological awareness and prevention campaigns of coccyx fracture. (C) 2020 Elsevier Ltd. All rights reserved. | Won, Heejae; Moon, Sun-Young; Park, Jae Hyun; Kim, Jin-Kak; Kim, Hong Seok; Baek, Seung-Hoon; Kim, Shin-Yoon; Lee, Young-Kyun; Koo, Kyung-Hoi | Kyungpook Natl Univ Hosp, Dept Orthopaed Surg, Daegu, South Korea; Seoul Natl Univ, Sch Publ Hlth, Dept Publ Hlth Sci, Complex Dis & Genome Epidemiol Branch, Seoul, South Korea; Seoul Natl Univ, Dept Orthopaed Surg, Bundang Hosp, 82 Gumi Ro,173 Beon Gil, Seongnam 13620, Gyeonggido, South Korea; Seoul Natl Univ, Dept Orthopaed Surg, Coll Med, 82 Gumi Ro,173 Beon Gil, Seongnam 13620, Gyeonggido, South Korea | Kim, Soo/J-5411-2012; Lee, Young-Kyun/D-6175-2012; Koo, Kyung-Hoi/D-7053-2012; Kim, Hyeun-Sung/H-3400-2018 | 57209207044; 57217872805; 57217866443; 57195109165; 57026504200; 56232924900; 26663842900; 15044971000; 23488849400 | INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED | INJURY | 0020-1383 | 1879-0267 | 51 | 10 | SCIE | CRITICAL CARE MEDICINE;EMERGENCY MEDICINE;ORTHOPEDICS;SURGERY | 2020 | 2.586 | 35.9 | 0.13 | 2025-06-25 | 6 | 4 | Coccyx fracture; Incidence; Epidemiology; Risk factors | COCCYGODYNIA; MORPHOLOGY; COCCYDYNIA | Coccyx fracture; Epidemiology; Incidence; Risk factors | Adolescent; Child; Coccyx; Female; Humans; Incidence; Male; Middle Aged; Osteoporotic Fractures; Republic of Korea; Risk Factors; Spinal Fractures; adolescent; adult; age distribution; Article; child; coccyx; female; fracture; health insurance; human; humidity; ICD-10; incidence; low temperature; major clinical study; male; menopause; precipitation; priority journal; risk factor; seasonal variation; South Korea; summer; temperature; wind speed; winter; coccyx; epidemiology; fragility fracture; middle aged; risk factor; spine fracture | English | 2020 | 2020-10 | 10.1016/j.injury.2020.07.019 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Intraoperative assessment of reduction quality during nail fixation of intertrochanteric fractures | Background: The quality of intertrochanteric fracture reduction has traditionally been evaluated using simple radiographs. However, subjective intraoperative evaluation and efforts to achieve a perfect reduction are essential for optimal outcomes. This study aimed to establish criteria for the intraoperative assessment of the quality of intertrochanteric fracture reduction and also analyzed postoperative outcomes in terms of reduction quality. Methods: This study included 106 patients who received cephalo-medullary nailing for the treatment of intertrochanteric fractures between March 2012 and May 2016 and were followed-up for at least 1 year. An image intensifier was used intraoperatively to evaluate reduction quality by examining the restoration of anteromedial cortex continuity, and neck-shaft angle and anteversion. Based on the reduction quality, the patients were classified into optimal, acceptable, and unacceptable groups, with intervention provided for the unacceptable group. The need for revision surgery and the degree of blade sliding were assessed, and postoperative outcomes related to implant position were analyzed. Results: Over 50% of patients with Arbeitsgemeinschaft fur Osteosynthesefragen/Orthopaedic Trauma Association (AO/OTA) type 31A2 and A3 fractures were assigned to the unacceptable group after closed reduction (P= 0.006), and 60 cases required additional reduction. Approximately 40% of cases classified as clinically unacceptable required revision, and the rate of sliding was >= 2-fold higher in the unacceptable group than those in the optimal and acceptable groups (P = 0.015), with an average excessive sliding of 9.85 mm. Regarding implant position, cut-out or penetration were observed in cases with superiorly-located blades (P = 0.039). Conclusions: Good outcomes cannot be achieved with traction alone for femoral intertrochanteric fractures. Active management is required because accurate anteromedial cortex reduction, and restoration of neck-shaft angle and anteversion are essential in femoral intertrochanteric fractures. (C) 2019 Elsevier Ltd. All rights reserved. | Yoon, Yong-Cheol; Oh, Chang-Wug; Sim, Jae-Ang; Oh, Jong-Keon | Gachon Univ, Trauma Ctr, Orthoped Trauma Div, Coll Med, Incheon, South Korea; Kyungpook Natl Univ Hosp, Dept Orthopaed Surg, Daegu, South Korea; Gachon Univ, Dept Orthopaed Surg, Coll Med, Incheon, South Korea; Korea Univ, Guro Hosp, Dept Orthopaed Surg, Coll Med, Seoul, South Korea | ; Oh, Chang-Wug/AAO-4602-2021; Yong-Cheol, Yoon/HPD-8077-2023 | 37082544400; 22135834200; 7202819253; 7402155046 | jkoh@korea.ac.kr; | INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED | INJURY | 0020-1383 | 1879-0267 | 51 | 2 | SCIE | CRITICAL CARE MEDICINE;EMERGENCY MEDICINE;ORTHOPEDICS;SURGERY | 2020 | 2.586 | 35.9 | 2.54 | 2025-06-25 | 29 | 35 | Intraoperative reduction assessment; Intertrochanteric fracture; Image intensifier | HIP-FRACTURES; INTRAMEDULLARY; PFNA; DHS | Image intensifier; Intertrochanteric fracture; Intraoperative reduction assessment | Accidental Falls; Accidents, Traffic; Aged; Aged, 80 and over; Bone Nails; Female; Fracture Fixation, Intramedullary; Fracture Healing; Hip Fractures; Humans; Injury Severity Score; Male; Postoperative Complications; Radiography; Retrospective Studies; Treatment Outcome; aged; Article; clinical outcome; closed fracture reduction; female; femur intertrochanteric fracture; hip radiography; human; intramedullary nailing; intraoperative period; major clinical study; male; postoperative period; priority journal; quality control; reoperation; retrospective study; surgical technique; adverse event; bone nail; diagnostic imaging; falling; fracture healing; hip fracture; injury scale; intramedullary nailing; pathology; postoperative complication; procedures; radiography; traffic accident; treatment outcome; very elderly | English | 2020 | 2020-02 | 10.1016/j.injury.2019.10.087 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Review | Miniplate osteosynthesis in fracture surgeries: Case series with review of concepts | Purpose: Miniplates were initially developed as targets for foot and hand fractures, but they have been used in the treatment of fixation of small bone fragments, reduction of long bone fractures and nonunion treatment, which have been difficult to treat. In this study, the authors used miniplates to treat fractures of the upper extremities, lower extremities, and pelvis obtained good outcomes. Herein, the authors report these good outcomes and review the current concept of miniplates. Patients and methods: Forty-two patients treated with miniplates between March 2012 and March 2017 who attended follow-up for > 1 year were included in this retrospective study. Miniplates were selected according to purpose, which was classified into three categories: fixation, reduction, and stability enhancement. For fixation, miniplates were used to fix distal fibular fractures occurring distal to the syndesmosis and treat patellar and olecranon fractures with severe comminution. For reduction, miniplates were used to reduce the tibia during intramedullary nailing in tibiofibular shaft fractures, while reduction was performed in advance of definitive plating fixation in patients with humeral and pelvic fractures. To enhance stability, the miniplate was inserted after autobone graft for atrophic nonunion at the humeral shaft following nail insertion. The validity of a miniplate was analyzed by reviewing the published literature on the use of miniplates in orthopedic fracture surgeries. Results: Bony union was achieved in all cases. No specific postoperative complications were observed; however, mild pain and limited range of motion observed in two patients were resolved after implant removal. Sixteen studies on fracture treatment using miniplates reported clinically fair outcomes. Conclusion: Miniplates are not just small metal plates. Depending on the location and treatment of the fracture, the miniplate can effectively fix small bone fragments, help the main plate to maintain the reduction of large bone fragments, and increase the fixation force for nonunion treatment. (C) 2020 Elsevier Ltd. All rights reserved. | Yoon, Yong-Cheol; Oh, Chang-Wug; Lee, Dong-Whan; Sim, Jae-Ang; Oh, Jong-Keon | Gachon Univ, Trauma Ctr, Orthoped Trauma Div, Coll Med, Incheon, South Korea; Kyungpook Natl Univ Hosp, Dept Orthopaed Surg, Daegu, South Korea; Gachon Univ, Dept Orthopaed Surg, Coll Med, Incheon, South Korea; Korea Univ, Guro Hosp, Dept Orthopaed Surg, Coll Med, 97 Guro Gu, Seoul 08308, South Korea | Yong-Cheol, Yoon/HPD-8077-2023; Oh, Chang-Wug/AAO-4602-2021 | 37082544400; 22135834200; 57215198564; 7202819253; 7402155046 | jkoh@korea.ac.kr; | INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED | INJURY | 0020-1383 | 1879-0267 | 51 | 4 | SCIE | CRITICAL CARE MEDICINE;EMERGENCY MEDICINE;ORTHOPEDICS;SURGERY | 2020 | 2.586 | 35.9 | 0.4 | 2025-06-25 | 6 | 6 | Miniplate; Fixation; Reduction; Stability | INTERNAL-FIXATION; OPEN REDUCTION; OPERATIVE TREATMENT; LOCKING PLATE; BIOMECHANICS; MANAGEMENT; OLECRANON; NONUNIONS | Fixation; Miniplate; Reduction; Stability | Adult; Aged; Aged, 80 and over; Bone Plates; Female; Fracture Fixation, Internal; Fractures, Bone; Humans; Male; Middle Aged; Postoperative Complications; Radiography; Retrospective Studies; Review Literature as Topic; acetabulum fracture; adult; aged; Article; bone graft; clinical article; clinical outcome; device removal; female; fibula fracture; follow up; fracture; fracture fixation; fracture nonunion; fracture reduction; human; humeral shaft; humerus fracture; humerus shaft fracture; intramedullary nailing; male; olecranon fracture; osteosynthesis; patella fracture; pelvis fracture; plate fixation; postoperative complication; postoperative pain; priority journal; range of motion; tibia shaft fracture; bone plate; devices; fracture; literature; middle aged; osteosynthesis; procedures; radiography; retrospective study; very elderly | English | 2020 | 2020-04 | 10.1016/j.injury.2020.02.044 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Preoperative "Computed tomography capsular sign" for the detection of occult ipsilateral femoral neck fractures associated with femoral shaft fractures | Aim: We scrutinised the computed tomography (CT) capsular sign, which refers to the anterior capsular distension of the hip, to determine whether we can use it as an additional clue for detecting occult ipsilateral femoral neck fracture (IFNF) before operation. Patients and Methods: We retrospectively examined 79 patients who suffered high-energy femoral shaft fracture and were evaluated with preoperative CT for occult IFNF. The occult IFNF was defined as a fracture that was not diagnosed confirmatively during preoperative evaluation. Thirteen patients were included in the occult IFNF group and 66 were included in the femoral neck intact group. A side-to-side difference of more than 1 mm of capsular distension was considered a positive CT capsular sign. Results: Among 13 patients in the occult IFNF group, 6 had a hairline fracture (bony window images) and 12 had a positive CT capsular sign (soft tissue window images) on preoperative CT scans. The presence of IFNF was more significantly associated with the CT capsular sign than with the hairline fracture (p = 0.031). Among the 66 patients in the femoral neck intact group, the CT capsular sign was false positive in 4. Conclusion: The CT capsular sign can be used to detect the presence of occult IFNF in high-energy trauma patients with femoral shaft fractures. During the preoperative evaluation of IFNF, surgeons must pay extra attention to the presence of occult IFNF when the CT capsular sign is positive. (C) 2020 Elsevier Ltd. All rights reserved. | Park, Young-Chang; Um, Kyu-Sub; Hong, Seung-Pyo; Oh, Chang-Wug; Kim, Sungjun; Yang, Kyu-Hyun | Catholic Kwandong Univ, Int ST Marys Hosp, Dept Orthoped Surg, Coll Med, Incheon, South Korea; Yonsei Univ, Gangnam Severance Hosp, Dept Orthoped Surg, Coll Med, 211 Eonju Ro, Seoul 135720, South Korea; Kyungpook Natl Univ, Sch Med, Dept Orthoped Surg, 130 Dongdeok Ro, Daegu, South Korea; Yonsei Univ, Gangnam Severance Hosp, Dept Radiol, Coll Med, 211 Eonju Ro, Seoul, South Korea | Oh, Chang-Wug/AAO-4602-2021; Hong, Raymond/R-6915-2019 | 57189715798; 56485493700; 57246937800; 22135834200; 57197815473; 37044135400 | kyang@yuhs.ac; | INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED | INJURY | 0020-1383 | 1879-0267 | 51 | 4 | SCIE | CRITICAL CARE MEDICINE;EMERGENCY MEDICINE;ORTHOPEDICS;SURGERY | 2020 | 2.586 | 35.9 | 1.34 | 2025-06-25 | 9 | 14 | Femoral shaft fracture; Ipsilateral femoral neck fracture; Occult fracture; Computed tomography; Preoperative evaluation | DIAGNOSIS; HIP; CT; FEMUR; LIPOHEMARTHROSIS; HEMARTHROSIS | Computed tomography; Femoral shaft fracture; Ipsilateral femoral neck fracture; Occult fracture; Preoperative evaluation | Adult; Aged; Female; Femoral Fractures; Femoral Neck Fractures; Fractures, Closed; Fractures, Stress; Humans; Male; Middle Aged; Preoperative Care; Republic of Korea; Retrospective Studies; Tomography, X-Ray Computed; Young Adult; adult; aged; Article; computer assisted tomography; disease association; false positive result; female; femoral neck; femoral neck fracture; femur shaft fracture; human; major clinical study; male; preoperative evaluation; priority journal; retrospective study; young adult; diagnostic imaging; femoral neck fracture; femur fracture; fracture; middle aged; preoperative care; South Korea; stress fracture; x-ray computed tomography | English | 2020 | 2020-04 | 10.1016/j.injury.2020.02.067 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Antibacterial activities of and biofilm removal by Ablysin, an endogenous lysozyme-like protein originated from Acinetobacter baumannii 1656-2 | Objectives: Multidrug-resistant (MDR) Acinetobacter baumannii as well as MDR Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Pseudomonas aeruginosa and other Enterobacteriaceae ('ESIKAPE' pathogens) currently present a major public-health problem. These bacteria are associated with opportunistic infections in intensive care units as well as in immunocompromised patients. There is an urgent need for new alternative antibacterials to control these MDR bacteria. Here we describe the antibacterial action of a novel peptidoglycan hydrolase that targets the bacterial cell wall, identified in the genome of clinical isolate A. baumannii 1656-2. Methods: We generated a recombinant protein from a sequence encoding a lysozyme-like protein identified in the genome of A. baumannii 1656-2. We named it Ablysin and tested its antibacterial activity and biofilm removal ability targeting ESKAPE pathogens. Results: In vitro application of Ablysin resulted in growth inhibition of the six aforementioned bacterial species, with a highest activity against A. baumannii. Electron microscopy revealed the concentration-dependent (250-2000 mu g/mL) rupture of A. baumannii bacterial cells accompanied by elimination of the associated biofilm. Conclusions: Ablysin represents a potential new class of antibacterial proteins that can be used to target MDR A. baumannii as well as other bacterial species. (C) 2020 The Author(s). Published by Elsevier Ltd on behalf of International Society for Antimicrobial Chemotherapy. | Kim, Shukho; Jin, Jong-Sook; Lee, Won; Kim, Jungmin | Kyungpook Natl Univ, Dept Microbiol, Sch Med, 680 Gukchaebosang Ro, Daegu 41944, South Korea | Kim, Jungmin/AAX-6484-2021; Kim, Shukho/AGG-1087-2022 | 24341187900; 22950662200; 57217049077; 57211297681 | shukhokim@knu.ac.kr;in75724@hanmail.net;dwdwdw0123@naver.com;minkim@knu.ac.kr; | JOURNAL OF GLOBAL ANTIMICROBIAL RESISTANCE | J GLOB ANTIMICROB RE | 2213-7165 | 2213-7173 | 23 | SCIE | INFECTIOUS DISEASES;PHARMACOLOGY & PHARMACY | 2020 | 4.035 | 36.0 | 0.35 | 2025-06-25 | 11 | 9 | Antibacterial activity; Antibiofilm activity; Lysozyme; Multidrug resistance; Acinetobacter baumannii | MOLECULAR EPIDEMIOLOGY; ANTIMICROBIAL ACTIVITY; RESISTANCE | Acinetobacter baumannii; Antibacterial activity; Antibiofilm activity; Lysozyme; Multidrug resistance | Acinetobacter baumannii; Anti-Bacterial Agents; Biofilms; Drug Resistance, Multiple, Bacterial; Humans; Muramidase; ablysin; antibiotic agent; carbapenem; cephalosporin; lysozyme; peptidoglycan; recombinant protein; unclassified drug; antiinfective agent; lysozyme; Acinetobacter baumannii; antibacterial activity; antibiofilm activity; Article; bacterial cell wall; bacterial genome; bacterium isolate; concentration process; electron microscopy; Enterococcus faecium; gene identification; gene sequence; genome analysis; growth inhibition; in vitro study; infectious agent; Klebsiella pneumoniae; nonhuman; priority journal; protein structure; Pseudomonas aeruginosa; Staphylococcus aureus; biofilm; genetics; human; multidrug resistance | English | 2020 | 2020-12 | 10.1016/j.jgar.2020.09.017 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Antimicrobial activity of LysSS, a novel phage endolysin, against Acinetobacter baumannii and Pseudomonas aeruginosa | Objectives: Multidrug-resistant (MDR) bacteria are a major public-health concern. Bacteriophage endolysins (lysins) can be used as novel antimicrobial agents against bacterial infections. In this study, a novel endolysin (LysSS) containing a lysozyme-like domain was evaluated for its antibacterial activity against various species of bacteria. Methods: The LysSS-encoding gene was analyzed and cloned and the LysSS recombinant protein was expressed and purified. Purified LysSS was used to determine its antimicrobial activity against various bacterial species in vitro and to measure its protection rate against Acinetobacter baumannii systemic infection in an in vivo murine model. Results: Recombinant LysSS showed activity against MDR A. baumannii, MDR Escherichia coli, MDR Klebsiella pneumoniae, MDR Pseudomonas aeruginosa and Salmonella sp. without pre-treatment with an outer membrane permeabiliser. Moreover, LysSS inhibited the growth of methicillin-resistant Staphylococcus aureus (MRSA). The minimum inhibitory concentration (MIC) of LysSS against 16 MDR A. baumannii strains ranged from 0.063-0.25 mg/mL. LysSS had no cytotoxic effect on A549 human lung cells below 250 mu g/mL. In an animal model, mice infected with A. baumannii were protected (40% survival rate with 125 mu g LysSS) by intraperitoneal injection of LysSS. Conclusion: The current results demonstrate that LysSS may be a novel and promising antimicrobial agent against MRSA and MDR Gram-negative bacteria, including A. baumannii and P. aeruginosa. (C) 2020 The Author(s). Published by Elsevier Ltd on behalf of International Society for Antimicrobial Chemotherapy. | Kim, Shukho; Lee, Da-Won; Jin, Jong-Sook; Kim, Jungmin | Kyungpook Natl Univ, Sch Med, Dept Microbiol, 680 Gukchaebosang Ro, Daegu 41944, South Korea | Kim, Shukho/AGG-1087-2022; Kim, Jungmin/AAX-6484-2021 | 24341187900; 57217049077; 22950662200; 57211297681 | minkim@knu.ac.kr; | JOURNAL OF GLOBAL ANTIMICROBIAL RESISTANCE | J GLOB ANTIMICROB RE | 2213-7165 | 2213-7173 | 22 | SCIE | INFECTIOUS DISEASES;PHARMACOLOGY & PHARMACY | 2020 | 4.035 | 36.0 | 3.05 | 2025-06-25 | 98 | 98 | Multidrug-resistant; Endolysin; Antimicrobial agent; Phage endolysin | ESCHERICHIA-COLI; BACTERIOPHAGE; SEQUENCE; RESISTANCE; INFECTION; ALIGNMENT; LYSIN | Antimicrobial agent; Endolysin; Multidrug-resistant; Phage endolysin | Acinetobacter baumannii; Animals; Anti-Infective Agents; Bacteriophages; Endopeptidases; Methicillin-Resistant Staphylococcus aureus; Mice; Pseudomonas aeruginosa; antibiotic agent; endolysin; recombinant protein; unclassified drug; antiinfective agent; endolysin; proteinase; Acinetobacter infection; animal experiment; animal model; antibacterial activity; antibiotic resistance; Article; bacterial growth; bacterial strain; bacteriophage; controlled study; cytotoxicity; female; growth inhibition; human; human cell; in vitro study; in vivo study; methicillin resistant Staphylococcus aureus; mouse; multidrug resistant Acinetobacter baumannii; multidrug resistant bacterium; multidrug resistant Escherichia coli; multidrug resistant Klebsiella pneumoniae; multidrug resistant Pseudomonas aeruginosa; nonhuman; priority journal; protein expression; protein purification; Salmonella; Salmonella enterica serovar Enteritidis; Salmonella enterica serovar Typhimurium; Staphylococcus aureus; Acinetobacter baumannii; animal; genetics; methicillin resistant Staphylococcus aureus; Pseudomonas aeruginosa | English | 2020 | 2020-09 | 10.1016/j.jgar.2020.01.005 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Modulation of sugar and nitrogen in callus induction media alter PAL pathway, SA and biomass accumulation in rice callus | In this study, the effect of varying nitrogen and sucrose concentrations in culture media was evaluated with respect to biomass production, accumulation of flavonoids, anthocyanin, and associated gene expression in rice callus. The callus was induced on control MS (M1), sugar-deficient (M2), sugar-excessive (M3), nitrogen-deficient (M4), and nitrogen-excessive (M5) media. The results indicated that the callus induction percentage (CIP) as well as the size and fresh weight of the callus were inhibited by all types of media compared with control media. Varying the sucrose and nitrogen concentration significantly affected callus morphology and caused a browning effect. Genes related to flavonoid biosynthesis (CHS, CHI, F3H, FLSandDFR) were upregulated in the callus cultured in all four media types compared with control media. Likewise, flavonoid and anthocyanin accumulation were higher in callus grown in excessive sugar- and nitrogen-containing media compared with control media. Unlike flavonoids, salicylic acid (SA) regulation was significantly higher in callus grown in sugar- and nitrogen-deficient media compared with control media. Sugar content was significantly higher in callus cultured in sugar-excessive media, whereas it was reduced in the callus cultured in the other media types compared with control media. Finally, chlorophyll was reduced in all callus media compared with the control media. Key message The current study concluded that, varying concentration of sugar and nitrogen inhibit callus development and morphology via alteration of secondary metabolites and their related genes. | Jan, Rahmatullah; Khan, Muhammad Aaqil; Asaf, Sajjad; Lee, In-Jung; Kim, Kyung-Min | Kyungpook Natl Univ, Div Plant Biosci, Sch Appl Biosci, Coll Agr & Life Sci, 80 Daehak Ro, Daegu 41566, South Korea; Univ Nizwa, Nat & Med Sci Res Ctr, Nizwa 616, Oman | ; Asaf, Sajjad/ABA-3647-2021; Kim, Kyung-Min Kim/C-7007-2014; Khan, Muhammad/ABB-9797-2021; Jan, Rahmatullah/AIC-3439-2022; Lee, In-Jung/GLS-0432-2022 | 57201981969; 57188585606; 56595059900; 16425830900; 34868260300 | kkm@knu.ac.kr; | PLANT CELL TISSUE AND ORGAN CULTURE | PLANT CELL TISS ORG | 0167-6857 | 1573-5044 | 143 | 3 | SCIE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY;PLANT SCIENCES | 2020 | 2.711 | 36.0 | 0.65 | 2025-06-25 | 10 | 9 | Flavonoids; Anthocyanin; Nitrogen; Callus induction; Chlorophyll | EFFICIENT PLANT-REGENERATION; SALICYLIC-ACID; NUTRIENT BALANCE; GENE-EXPRESSION; SOMATIC EMBRYOGENESIS; ANTHOCYANIN SYNTHESIS; NITRATE REDUCTASE; ROOTING MEDIUM; AMINO-ACIDS; GROWTH | Anthocyanin; Callus induction; Chlorophyll; Flavonoids; Nitrogen | Anthocyanins; Biochemistry; Callus; Control Systems; Culture Media; Nitrogen; Salicylic Acid; Sugar; Anthocyanins; Biochemistry; Gene expression; Salicylic acid; Sugar (sucrose); Anthocyanin accumulation; Biomass accumulation; Biomass productions; Callus induction; Culture media; Nitrogen concentrations; Sucrose concentration; Sugar content; Nitrogen | English | 2020 | 2020-12 | 10.1007/s11240-020-01938-8 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Protoplast isolation and shoot regeneration from protoplast-derived calli of Chrysanthemum cv. White ND | Key message The regeneration of chrysanthemum protoplasts into whole plants is difficult due to the recalcitrant nature of these plants and because of their genotype-dependent response. This study is appropriate for protoplast isolation and callus formation of Chrysanthemum cv. White ND, and it also achieved regenerating chrysanthemum protoplasts-derived calli into whole plants. In this study, we sought to optimize the isolation of protoplasts from chrysanthemums by manipulating the mannitol and cellulase levels, the incubation period, and the purification method, followed by the conversion of the protoplasts into calli and shoots. A high protoplast yield was achieved using 0.5 M mannitol, 1.5% cellulase, and a 4 h incubation period. Cell wall regeneration was observed after 3 days, with the first cell division occurring approximately 4-5 days after culturing. The addition of sucrose to the culture media was more beneficial than glucose; in sucrose media the protoplasts grew more rapidly and successfully reached the colony and microcalli stage. The addition of activated charcoal to the culture improved colony and microcalli formation. Greater proliferation of microcalli was also achieved using solid Murashige & Skoog (MS) media supplemented with 1 mg l(-1) 6-Benzylaminopurine (BA) and 2 mg l(-1) Naphthaleneacetic acid (NAA). The calli produced shoots THE on media supplemented with 2 mg l(- 1) BA and 0.5 mg l(-1) NAA. These findings could facilitate further chrysanthemum protoplast-based research. | Adedeji, Oluwaseun Suleimon; Naing, Aung Htay; Kim, Chang Kil | Kyungpook Natl Univ, Dept Hort Sci, Daegu 41566, South Korea | ; Adedeji, Oluwaseun/IUN-2788-2023; Naing, Aung Htay/AAF-4277-2019 | 57216153720; 37112768100; 7409880701 | aunghtaynaing2005@gmail.com;ckkim@knu.ac.kr; | PLANT CELL TISSUE AND ORGAN CULTURE | PLANT CELL TISS ORG | 0167-6857 | 1573-5044 | 141 | 3 | SCIE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY;PLANT SCIENCES | 2020 | 2.711 | 36.0 | 3.49 | 2025-06-25 | 34 | 32 | Chrysanthemum; Protoplast isolation; Shoot regeneration; Colony formation; Activated charcoal; Plant growth regulators | MEDIATED GENETIC-TRANSFORMATION; GRANDIFLORUM RAMAT. KITAMURA; PLANT-REGENERATION; ACTIVATED-CHARCOAL; SOMATIC HYBRIDS; EXPLANT SOURCE; CULTURE; SELECTION; SYSTEM; GROWTH | Activated charcoal; Chrysanthemum; Colony formation; Plant growth regulators; Protoplast isolation; Shoot regeneration | Activated Carbon; Cellulase; Culture Media; Growth Regulators; Mannitol; Polyols; Protoplasm; Shoots; Activated carbon; Cell proliferation; Growth kinetics; Polyols; Sugar (sucrose); Chrysanthemum; Colony formation; Plant growth regulators; Protoplast isolation; Shoot regeneration; Plants (botany) | English | 2020 | 2020-06 | 10.1007/s11240-020-01816-3 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | 3D structural analysis of PI blend/BN composite film with FTIR spectro-microtomography | A Fourier transform infrared (FTIR) spectro-microtomography system was used to conduct a 3-dimensional (3D) structural analysis of a Polyimide (PI) blend/boron nitride (BN) composite film, and the system was optimized by measuring materials with complex shapes, including a micrometer-sized loop and commercial PAN fiber. The results of the 3D reconstruction of the microloop and PAN fiber are in good agreement with optical and chemical images. In addition, the FTIR spectro-microtomography successfully described the phase separation behaviors of the PI blend/BN composite film in a 3D representation. Thereby, we could observe the internal structure of the blend film, which improves the thermal conduction in the out-of-plane direction. | Kim, Jiho; Park, Jae Yeon; Kim, Hye Ji; Lee, Sangsul; Shin, Yoseob; Lee, Seung Woo; Chae, Boknam | POSTECH, Pohang Accelerator Lab, Pohang 37673, South Korea; Korea Atom Energy Res Inst, Radiat Equipment Res Div, Jeongup 56212, South Korea; Kyungpook Natl Univ, Dept Polymer Sicence & Engn, Daegu 41566, South Korea; Yeungnam Univ, Sch Chem Engn, Gyongsan 38541, South Korea | ; Lee, Sangsul/AAA-1088-2022; kim, hye/AAF-8671-2019 | 56997818500; 57214313665; 57214326896; 15925429900; 57212486735; 57211365101; 7005986114 | leesw1212@ynu.ac.kr;cbn@postech.ac.kr; | VIBRATIONAL SPECTROSCOPY | VIB SPECTROSC | 0924-2031 | 1873-3697 | 110 | SCIE | CHEMISTRY, ANALYTICAL;CHEMISTRY, PHYSICAL;SPECTROSCOPY | 2020 | 2.507 | 36.1 | 0 | 2025-06-25 | 1 | 1 | Polyimide; Boron nitride; Phase separation; FTIR spectro-microtomography | HEXAGONAL BORON-NITRIDE; ENHANCED THERMAL-CONDUCTIVITY; POLYMER COMPOSITES; POLYIMIDE FILMS; THIN-FILMS; ALIGNMENT; NANOCOMPOSITES; ORIENTATION; PERFORMANCE; STABILITY | Boron nitride; FTIR spectro-microtomography; Phase separation; Polyimide | Blending; Composite films; Phase separation; Structural analysis; Tomography; 3D reconstruction; 3d representations; 3D structural analysis; Fourier transform infrared; Internal structure; Out-of-plane direction; Phase separation behavior; Thermal conduction; Fourier transform infrared spectroscopy | English | 2020 | 2020-09 | 10.1016/j.vibspec.2020.103144 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | The inhibitory effect of curcumin via fascin suppression through JAK/STAT3 pathway on metastasis and recurrence of ovary cancer cells | Background Fascin is an actin-binding protein and highly expressed in ovarian cancer cells. It is associated with metastasis of cancer and may be a useful prognostic factor. Anticancer activity of curcumin is related to its effect on several signaling mechanisms. Although there have been many reports regarding the anticancer properties of curcumin, its inhibitory effects on migration and invasion of ovarian cancer cells, particularly in the context of fascin expression, have not been reported. The purpose of this study was to investigate the effect of curcumin on fascin expression in ovarian cancer cells and to propose a possible mechanism for the anticancer activity of curcumin through reduced fascin expression. Methods SKOV3, human epithelial ovary cancer cell line, was cultured with curcumin at various dose and duration. The fascin was quantified using cell viability test and Western blot. To determine the effect of curcumin on the upstream pathway of fascin expression, the signal transducer and activator of transcription 3 (STAT3) was analyzed by sandwich-ELISA. Attachment assay, migration assay and invasion assay were analyzed to approve the change of cellular invasiveness of ovary cancer after curcumin. To determine the morphological changes of ovarian cancer cells by curcumin, immunofluorescence was performed. Results MTS assays showed that cell viability was different at various concentration of curcumin, and as concentration increased, cell viability tended to decrease. Curcumin appears to suppress fascin expression, even with a minimal concentration and short exposure time. Also, curcumin may suppress fascin expression in ovarian cancer cells through STAT3 downregulation. The attachment assay, migration assay and invasion assay of the ovarian cancer cells exhibited a statistically significant decrease. Immunofluorescence revealed a change of cell shape from a typical form of uninfluenced cells to a more polygonal appearance, with a significant reduction in filopodia formation. Conclusions Curcumin reduces fascin expression through JAK/STAT3 pathway inhibition, which interferes with the cellular interactions essential for the metastasis and recurrence of ovarian cancer cells. Higher curcumin concentrations and longer exposure times concomitantly decreased fascin expression. | Kim, Mi Ju; Park, Ki-Su; Kim, Kyoung-Tae; Gil, Eun Young | Kyungpook Natl Univ, Sch Med, Kyungpook Natl Univ Hosp, Dept Obstet & Gynecol, 130 Dongdeok Ro, Daegu 41944, South Korea; Kyungpook Natl Univ, Sch Med, Dept Neurosurg, Daegu, South Korea | Kim, Mi Ju/HGU-8470-2022 | 55908927600; 55932363100; 57201369790; 57211061205 | ties1004@naver.com; | BMC WOMENS HEALTH | BMC WOMENS HEALTH | 1472-6874 | 20 | 1 | SCIE;SSCI | OBSTETRICS & GYNECOLOGY;PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | 2020 | 2.809 | 36.1 | 1.68 | 2025-06-25 | 22 | 24 | Ovary cancer; Curcumin; Fascin; JAK; STAT3 pathway | GROWTH-FACTOR; ANTICANCER; APOPTOSIS; MIGRATION; INVASION | Curcumin; Fascin; JAK/STAT3 pathway; Ovary cancer | Carrier Proteins; Curcumin; Female; Humans; Janus Kinases; Microfilament Proteins; Neoplasm Metastasis; Neoplasm Recurrence, Local; Ovarian Neoplasms; Signal Transduction; STAT3 Transcription Factor; curcumin; fascin; Janus kinase; STAT3 protein; actin binding protein; carrier protein; fascin; Janus kinase; STAT3 protein; antineoplastic activity; Article; cancer inhibition; cancer recurrence; cell adhesion assay; cell invasion assay; cell migration assay; cell shape; cell structure; cell viability; cell viability assay; concentration (parameter); concentration response; controlled study; down regulation; drug exposure; drug mechanism; filopodium; human; human cell; immunofluorescence; metastasis inhibition; protein expression; sandwich ELISA; signal transduction; SK-OV-3 cell line; tumor invasion; Western blotting; drug effect; female; metabolism; metastasis; ovary tumor; pathology; signal transduction; tumor recurrence | English | 2020 | 2020-12-19 | 10.1186/s12905-020-01122-2 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | Letter | Development of Crohn's disease in a child with SLC26A3-related congenital chloride diarrhea: Report of the first case in East Asia and a novel missense variant | [No abstract available] | Kim, Eun Sil; Song, Ju Sun; Ki, Chang-Seok; Choe, Yon Ho; Kang, Ben | Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; GC Genome, Yongin, South Korea, Department of Laboratory Medicine, Green Cross Laboratories, Yongin, South Korea; GC Genome, Yongin, South Korea; Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; Department of Pediatrics, School of Medicine, Kyungpook National University, Daegu, South Korea | 57205500267; 59873189700; 56800160200; 21333712100; 57194823199 | Annals of Laboratory Medicine | ANN LAB MED | 2234-3806 | 2234-3814 | 41 | 2 | SCIE | MEDICAL LABORATORY TECHNOLOGY | 2020 | 3.464 | 36.2 | 0.12 | 2025-06-25 | 2 | Child; Chloride-Bicarbonate Antiporters; Crohn Disease; Diarrhea; Far East; Humans; Metabolism, Inborn Errors; Sulfate Transporters; bicarbonate chloride antiporter; SLC26A3 protein, human; case report; child; Crohn disease; diarrhea; Far East; human; inborn error of metabolism | English | Final | 2020 | 10.3343/alm.2021.41.2.255 | 바로가기 | 바로가기 | 바로가기 | |||||||||
| ○ | ○ | Article | Prevalence, Mortality, and Cause of Death in Charcot-Marie-Tooth Disease in Korea: A Nationwide, Population-Based Study | Background: Charcot-Marie-Tooth disease (CMT) is a group of clinically and genetically heterogeneous disorders that primarily affect the peripheral nervous system. Epidemiological studies of CMT have not yet been performed in Korea. Objectives: This study was performed to estimate the prevalence of CMT in Korea and the socioeconomic status, mortality, and causes of death of Korean patients with CMT. Methods: Data on patients with CMT were obtained from the rare intractable disease registry and the National Health Insurance Service for the years 2005-2018. Results: During the study period, 2,885 CMT patients were enrolled. The prevalence per 100,000 persons in 2018 was 5.2 (6.1 for men and 4.4 for women), peaking at ages 15-39 years, with almost twice as many men (n = 714) as women (n = 402) in this age group. Of the CMT patients, 226 (7.8%) were receiving medical aid, a public assistance program targeting poor individuals, at the time of diagnosis and 253 (8.8%) at last follow-up or death. From 2005 to 2017, 170 patients died, including 118 men and 52 women. The standardized mortality ratio (SMR) was 1.57 (95% CI 1.34-1.83) for all patients and did not differ in men and women. Age-specific SMR was highest in patients aged under 9 years, gradually declining thereafter. Neurologic disease as a cause of death was significantly more frequent in CMT patients than in the general population. Conclusions: This was the first nationwide epidemiologic study of CMT patients in Korea. This study confirmed the characteristics associated with the prevalence of and mortality from CMT by age and is the first to report the socioeconomic status and causes of death of CMT patients. | Park, HyungJun; Choi, Young-Chul; Oh, JiWon; Yi, Sang-Wook | Univ Ulsan, Coll Med, Gangneung Asan Hosp, Dept Neurol, Kangnung, South Korea; Yonsei Univ, Coll Med, Dept Neurol, Seoul, South Korea; Kyungpook Natl Univ, Sch Med, Dept Anat, Daegu, South Korea; Catholic Kwandong Univ, Coll Med, Dept Prevent Med & Publ Hlth, Bumil Ro 579 Beon Gil 24, Kangnung 25601, Gangwon Do, South Korea | ; Oh, Ji/AAZ-3153-2020 | 55989522800; 7404776179; 36093206200; 7201404261 | flyhigh@cku.ac.kr; | NEUROEPIDEMIOLOGY | NEUROEPIDEMIOLOGY | 0251-5350 | 1423-0208 | 54 | 4 | SCIE | CLINICAL NEUROLOGY;PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | 2020 | 3.282 | 36.2 | 0.52 | 2025-06-25 | 7 | 9 | Charcot-Marie-Tooth disease; Prevalence; Mortality; Cause of death; Epidemiology | NEUROPATHIES; MOTOR | Cause of death; Charcot-Marie-Tooth disease; Epidemiology; Mortality; Prevalence | Adolescent; Adult; Aged; Aged, 80 and over; Cause of Death; Charcot-Marie-Tooth Disease; Child; Female; Humans; Male; Middle Aged; Prevalence; Registries; Republic of Korea; Social Class; Young Adult; adolescent; adult; aged; cause of death; child; female; hereditary motor sensory neuropathy; human; male; middle aged; mortality; prevalence; register; social class; South Korea; very elderly; young adult | English | 2020 | 2020-07 | 10.1159/000505815 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | Article | Prospective cohort data quality assurance and quality control strategy and method: Korea HIV/AIDS Cohort Study | OBJECTIVES: The aim of effective data quality control and management is to minimize the impact of errors on study results by identifying and correcting them. This study presents the results of a data quality control system for the Korea HIV/AIDS Cohort Study that took into account the characteristics of the data. METHODS: The HIV/AIDS Cohort Study in Korea conducts repeated measurements every 6 months using an electronic survey administered to voluntarily consenting participants and collects data from 21 hospitals. In total, 5,795 sets of data from 1,442 participants were collected from the first investigation in 2006 to 2016. The data refining results of 2015 and 2019 were converted into the data refining rate and compared. RESULTS: The quality control system involved 3 steps at different points in the process, and each step contributed to data quality management and results. By improving data quality control in the pre-phase and the data collection phase, the estimated error value in 2019 was 1,803, reflecting a 53.9% reduction from 2015. Due to improvements in the stage after data collection, the data refining rate was 92.7% in 2019, a 24.21%p increase from 2015. CONCLUSIONS: Despite this quality management strategy, errors may still exist at each stage. Logically possible errors for the post-review refining of downloaded data should be actively identified with appropriate consideration of the purpose and epidemiological characteristics of the study data. To improve data quality and reliability, data management strategies should be systematically implemented. | Kim, Soo Min; Choi, Yunsu; Choi, Bo Youl; Kim, Minjeong; Kim, Sang Il; Choi, Jun Young; Kim, Shin-Woo; Song, Joon Young; Kim, Youn Jeong; Kee, Mee-Kyung; Yoo, Myeongsu; Lee, Jeong Gyu; Park, Bo Young | Yonsei Univ, Dept Appl Stat, Coll Commerce & Econ, Seoul, South Korea; Yonsei Univ, Dept Stat & Data Sci, Coll Commerce & Econ, Seoul, South Korea; Hanyang Univ, Inst Hlth & Soc, Seoul, South Korea; Hanyang Univ, Dept Prevent Med, Coll Med, 222 Wangsimni Ro, Seoul 04763, South Korea; Catholic Univ Korea, Coll Med, Dept Internal Med, Div Infect Dis,Seoul St Marys Hosp, Seoul, South Korea; Yonsei Univ, Dept Internal Med, Coll Med, Seoul, South Korea; Yonsei Univ, AIDS Res Inst, Coll Med, Seoul, South Korea; Kyungpook Natl Univ, Dept Internal Med, Sch Med, Daegu, South Korea; Korea Univ, Dept Internal Med, Div Infect Dis, Coll Med, Seoul, South Korea; Catholic Univ Korea, Coll Med, Dept Internal Med, Div Infect Dis,Incheon St Marys Hosp, Incheon, South Korea; Korea Natl Inst Hlth, Div Viral Dis, Res Ctr Infect Dis Res, Cheongju, South Korea | ; Choi, Yunsu/AAH-1260-2021; Kim, Sooyeon/AAA-8521-2022; Choi, Jah/AAA-4835-2022; Kim, Sun/G-3451-2013 | bychoi@hanyang.ac.kr; | EPIDEMIOLOGY AND HEALTH | EPIDEMIOL HEALTH | 2092-7193 | 42 | SCIE | PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH | 2020 | 3.282 | 36.2 | 3 | HIV/AIDS; Quality control; Cohort studies; Data adjustment; Data quality; Data accuracy | English | 2020 | 2020-09-04 | 10.4178/epih.e2020063 | 바로가기 | 바로가기 | 바로가기 |
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