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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | Article | Transcranial focused ultrasound stimulation of cortical and thalamic somatosensory areas in human | The effects of transcranial focused ultrasound (FUS) stimulation of the primary somatosensory cortex and its thalamic projection (i.e., ventral posterolateral nucleus) on the generation of electroencephalographic (EEG) responses were evaluated in healthy human volunteers. Stimulation of the unilateral somatosensory circuits corresponding to the non-dominant hand generated EEG evoked potentials across all participants; however, not all perceived stimulation-mediated tactile sensations of the hand. These FUS-evoked EEG potentials (FEP) were observed from both brain hemispheres and shared similarities with somatosensory evoked potentials (SSEP) from median nerve stimulation. Use of a 0.5 ms pulse duration (PD) sonication given at 70% duty cycle, compared to the use of 1 and 2 ms PD, elicited more distinctive FEP peak features from the hemisphere ipsilateral to sonication. Although several participants reported hearing tones associated with FUS stimulation, the observed FEP were not likely to be confounded by the auditory sensation based on a separate measurement of auditory evoked potentials (AEP) to tonal stimulation (mimicking the same repetition frequency as the FUS stimulation). Off-line changes in resting-state functional connectivity (FC) associated with thalamic stimulation revealed that the FUS stimulation enhanced connectivity in a network of sensorimotor and sensory integration areas, which lasted for at least more than an hour. Clinical neurological evaluations, EEG, and neuroanatomical MRI did not reveal any adverse or unintended effects of sonication, attesting its safety. These results suggest that FUS stimulation may induce long-term neuroplasticity in humans, indicating its neurotherapeutic potential for various neurological and neuropsychiatric conditions. | Kim, Hyun-Chul; Lee, Wonhye; Weisholtz, Daniel; Yoo, Seung-Schik | Harvard Med Sch, Brigham & Womens Hosp, Dept Radiol, Boston, MA 02115 USA; Harvard Med Sch, Brigham & Womens Hosp, Dept Neurol, Boston, MA USA; Kyungpook Natl Univ, Dept Artificial Intelligence, Daegu, South Korea | Kim, Leehyung/AAN-6760-2020; Lee, Wonhye/J-5166-2016 | yoo@bwh.harvard.edu; | PLOS ONE | PLOS ONE | 1932-6203 | 18 | 7 | SCIE | MULTIDISCIPLINARY SCIENCES | 2023 | 2.9 | 23.5 | 11 | STATE FUNCTIONAL CONNECTIVITY; ANTERIOR CINGULATE; MAGNETIC STIMULATION; BRAIN-STIMULATION; MOTOR; NEUROMODULATION; THRESHOLDS; HANDEDNESS; DISORDERS; PHOSPHENE | English | 2023 | 2023-07-21 | 10.1371/journal.pone.0288654 | 바로가기 | 바로가기 | 바로가기 | |||||||||||
| ○ | ○ | Article | Transcriptome profiling for developmental stages Protaetia brevitarsis seulensis with focus on wing development and metamorphosis | A white-spotted flower chafer Protaetia brevitarsis seulensis widely distributed in Asian countries is traditionally used in oriental medicine. This study explored gene expression abundance with respect to wing development and metamorphosis in P. b. seulensis based on the large-scale RNA-seq data. The transcriptome assembly consists of 23,551 high-quality transcripts which are approximately 96.7% covered. We found 265 wing development genes, 19 metamorphosis genes, and 1,314 candidates. Of the 1,598 genes, 1,594 are included exclusively in cluster 4 with similar gene co-expression patterns. The network centrality analyses showed that wing development- and metamorphosis-related genes have a high degree of betweenness centrality and are expressed most highly in eggs, moderately in pupa and adults, and lowest in larva. This study provides some meaningful clues for elucidating the genetic modulation mechanism of wing development and metamorphosis in P. b. seulensis. | Hwang, Jihye; Choi, Eun Hwa; Park, Bia; Kim, Gyeongmin; Shin, Chorong; Lee, Joon Ha; Hwang, Jae Sam; Hwang, Ui Wook | Kyungpook Natl Univ, Teachers Coll, Dept Biol Educ, Daegu, South Korea; Kyungpook Natl Univ, Inst Phylogen & Evolut, Dept Biol Educ, Daegu, South Korea; Phylomics Inc, Daegu, South Korea; Kyungpook Natl Univ, Sch Life Sci, Grad Sch, Daegu, South Korea; Kyungpook Natl Univ, Sch Ind Technol Adv, Daegu, South Korea; Natl Inst Agr Sci, Dept Agr Biol, Rural Dev Adm, Wonju, South Korea; Kyungpook Natl Univ, Inst Korean Herb Bio Convergence Promot, Daegu, South Korea | Choi, Eun Hwa/HTN-1610-2023 | 57219609298; 57203556599; 57191834404; 57211378109; 57222521654; 37960965000; 16637012100; 35074015800 | uwhwang1@gmail.com; | PLOS ONE | PLOS ONE | 1932-6203 | 18 | 3 | SCIE | MULTIDISCIPLINARY SCIENCES | 2023 | 2.9 | 23.5 | 0.35 | 2025-06-25 | 3 | 3 | WHOLE-GENOME; INSIGHTS; GROWTH; GENE; ANNOTATION; DROSOPHILA; EVOLUTION | Animals; Coleoptera; Gene Expression Profiling; Larva; RNA-Seq; Transcriptome; complementary DNA; double stranded DNA; messenger RNA; transcriptome; transcriptome; adult; Article; beetle; controlled study; developmental stage; differential gene expression; DNA binding; DNA fragmentation; DNA synthesis; down regulation; endoplasmic reticulum; gene expression level; gene interaction; genome size; illumina sequencing; larva; metamorphosis; nonhuman; phylogenetic tree; phylogeny; Protaetia brevitarsis seulensis; protein processing; protein protein interaction; pupa; ribosome; RNA extraction; RNA fingerprinting; RNA isolation; RNA sequence; RNA sequencing; RNA transport; sequence alignment; spliceosome; trend study; upregulation; wing; animal; gene expression profiling | English | 2023 | 2023-03-01 | 10.1371/journal.pone.0277815 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Origin of Topological Hall-Like Feature in Epitaxial SrRuO3 Thin Films | The discovery of topological Hall effect (THE) has important implications for next-generation high-density nonvolatile memories, energy-efficient nanoelectronics, and spintronic devices. Both real-space topological spin configurations and two anomalous Hall effects (AHE) with opposite polarity due to two magnetic phases have been proposed for THE-like feature in SrRuO3 (SRO) films. In this work, SRO thin films with and without THE-like features are systematically Investigated to decipher the origin of the THE feature. Magnetic measurement reveals the coexistence of two magnetic phases of different coercivity (H-c) in both the films, but the hump feature cannot be explained by the two channel AHE model based on these two magnetic phases. In fact, the AHE is mainly governed by the magnetic phase with higher H-c. A diffusive Berry phase transition model is proposed to explain the THE feature. The coexistence of two Berry phases with opposite signs over a narrow temperature range in the high Hc magnetic phase can explain the THE like feature. Such a coexistence of two Berry phases is due to the strong local structural tilt and microstructure variation in the thinner films. This work provides an insight between structure/micro structure and THE like features in SRO epitaxial thin films. | Roy, Pinku; Carr, Adra; Zhou, Tao; Paudel, Binod; Wang, Xuejing; Chen, Di; Kang, Kyeong Tae; Pateras, Anastasios; Corey, Zachary; Lin, Shizeng; Zhu, Jian-Xin; Holt, Martin V.; Yoo, Jinkyoung; Zapf, Vivien; Zeng, Hao; Ronning, Filip; Jia, Quanxi; Chen, Aiping | Univ Buffalo, State Univ New York, Dept Mat Design & Innovat, Buffalo, NY 14260 USA; Los Alamos Natl Lab, Ctr Integrated Nanotechnol CINT, Los Alamos, NM 87545 USA; Argonne Natl Lab, Ctr Nanoscale Mat, Lemont, IL 60439 USA; Univ Houston, Ctr Superconduct, Dept Phys & Texas, Houston, TX 77204 USA; Kyungpook Natl Univ, Dept Phys, Daegu 41566, South Korea; Carnegie Mellon Univ, Dept Mat Sci & Engn, Pittsburgh, PA 15213 USA; T 4 Alamos Natl Lab, T 4 & Ctr Integrated Nanotechnol CINT, Los Alamos, NM 87545 USA; Alamos Natl Lab, Natl High Magnet Field Lab, Los Alamos, NM 87545 USA; Univ Buffalo, State Univ New York, Dept Phys, Buffalo, NY 14260 USA; Alamos Natl Lab, MPA Q, Los Alamos, NM 87545 USA | ; Zhu, Jianxin/H-9763-2018; Yoo, Jinkyoung/B-5291-2008; Zeng, Hao/AAD-8060-2021; Zhou, Tao/MBV-8202-2025; Jia, Quanxi/Q-5614-2019; Lin, Shi-Zeng/B-2906-2008; Chen, Aiping/F-3212-2011; Zapf, Vivien/K-5645-2013 | 57199145396; 36707259900; 57193234906; 57208564825; 57202370307; 56905024600; 56002123900; 56451191100; 57423635300; 23470230600; 55508216700; 10144638300; 8561080400; 6603629385; 7401472212; 7004185634; 7102029237; 55265473100 | qxjia@buffalo.edu;apchen@lanl.gov; | ADVANCED ELECTRONIC MATERIALS | ADV ELECTRON MATER | 2199-160X | 9 | 6 | SCIE | MATERIALS SCIENCE, MULTIDISCIPLINARY;NANOSCIENCE & NANOTECHNOLOGY;PHYSICS, APPLIED | 2023 | 5.3 | 23.7 | 0.99 | 2025-06-25 | 8 | 9 | anomalous hall effect; epitaxial; SrRuO3; thin films; topological hall effect | WEYL | anomalous hall effect; epitaxial; SrRuO<sub>3</sub>; thin films; topological hall effect | Energy efficiency; Fruits; Ruthenium compounds; Strontium compounds; Topology; Anomalous hall effects; Berry's phase; Epitaxial; Magnetic phase; Memory energies; Non-volatile memory; Nonvolatile memory; SrRuO 3; Thin-films; Topological hall effect; Thin films | English | 2023 | 2023-06 | 10.1002/aelm.202300020 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Predicting the Refrigerant Amounts Across Air Conditioners With a Domain Adaptive Lightweight Transformer | Air conditioner consumers expect their products to work well without any problem. Consumers encounter problems if the amount of refrigerant in the air conditioner is insufficient. Therefore, we propose a novel deep learning approach that predicts the amount of refrigerant in advance. Our approach differs from others, as it is not limited to specific types of air conditioners and is applicable to all types. We propose a domain adaptive Transformer (DAT) that determines the amount of refrigerant using a Transformer encoder and domain adversarial training of neural networks. The proposed DAT reduces the model parameters by using a modified lightweight Transformer encoder and adds a domain classifier to build a universal model that is not limited to a specific type of air conditioner. We conduct the experiments by collecting data on the amount of refrigerant operating in the real fields. As a result, the proposed DAT achieves higher prediction performance. It is also significant that the results predicted by DAT are more accurate than those predicted by experts dealing with air conditioner refrigerant problems. As a result, DAT-based air conditioners are commercialized in real life. Hence, consumers can prevent the shortage of refrigerant without experts. | Hwang, Kyoungho; Lee, Junwon; Jalali, Amin; Lee, Minho | Kyungpook Natl Univ, Grad Sch Artificial Intelligence, Daegu 41566, South Korea; Kyungpook Natl Univ, AI Inst Technol, KNU LG Elect Convergence Res Ctr, Daegu 41566, South Korea; Kyungpook Natl Univ, AI Inst Technol, Grad Sch Artificial Intelligence, Daegu 41566, South Korea; Kyungpook Natl Univ, AI Inst Technol, KNU LG Elect Convergence Res Ctr, Daegu 41566, South Korea | Lee, Min-Ho/ABE-5735-2021; Jalali, Amin/AAH-6921-2019 | 58002214700; 57641592200; 57022190400; 57191730119 | ririz.papa@gmail.com;zini9405@gmail.com;max.jalali@gmail.com;mholee@gmail.com; | IEEE TRANSACTIONS ON CONSUMER ELECTRONICS | IEEE T CONSUM ELECTR | 0098-3063 | 1558-4127 | 69 | 3 | SCIE | ENGINEERING, ELECTRICAL & ELECTRONIC;TELECOMMUNICATIONS | 2023 | 4.3 | 23.7 | 0.54 | 2025-06-25 | 4 | 5 | Air conditioner; domain adaptation; deep learning; transformer | ADAPTATION; ATTENTION | Air conditioner; deep learning; domain adaptation; transformer | Air conditioning; Deep learning; Domestic appliances; Signal encoding; Adaptation models; Air conditioner; Atmospheric modeling; Deep learning; Domain adaptation; Learning approach; Predictive models; Transformer; Refrigerants | English | 2023 | 2023-08 | 10.1109/tce.2023.3278283 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Rational Design Strategy for Triboelectric Nanogenerators Based on Electron Back Flow and Ionic Defects: The Case of Polytetrafluoroethylene | The lack of theoretical understanding of triboelectrification has hindered the development of energy harvesting technologies like triboelectric nanogenerators. Focusing on polytetrafluoroethylene, a material with a strong triboelectric output, a model predictive of its triboelectric behavior, driving the development of improved nanogenerators are formulated. With a combined computational-experimental approach it is shown that defluorination enhances polytetrafluoroethylene nanoscale triboelectric charging. Then a model, explaining the macroscale triboelectric output as determined by the competition of two mechanisms is developed. Defluorination enhances charging while also reducing the interface gap, favoring the backflow of electrons, and possibly reducing charging. However, numerical analysis shows that backflow is negligible, aligning with the prediction of increased triboelectric output. By building triboelectric nanogenerators with defluorinated polytetrafluoroethylene samples, achieved by X-ray irradiation, a one-order-of-magnitude output increase is demonstrated. The predictive models, supported by experiments, lead to an improved strategy for designing effective energy harvesting devices and new applicative breakthroughs. Density functional theory calculations and theoretical modeling show that polytetrafluoroethylene (PTFE) triboelectric properties can be highly enhanced by defluorination, which can be experimentally obtained by X-ray irradiation. Triboelectric measurements validate the prediction and prove its generality by pairing PTFE with both metals and polymers, demonstrating the power of theoretical modeling to facilitate applicative breakthroughs.image | Fatti, Giulio; Ciniero, Alessandra; Ko, Hyunseok; Lee, Han Uk; Na, Yujin; Jeong, Chang Kyu; Lee, Sang-Geul; Kwak, Dongyub; Park, Kwi-Il; Cho, Sung Beom; Dini, Daniele | Imperial Coll London, Dept Mech Engn, Tribol Grp, London SW7 2BX, England; Korea Inst Ceram Engn & Technol KICET, Ctr Mat Digitalizat, Jinju 52851, Gyeongsangnam D, South Korea; Korea Inst Ceram Engn & Technol KICET, Mat Digitalizat Ctr, Jinju 52851, Gyeongsangnam D, South Korea; Ajou Univ, Dept Energy Syst Res, Suwon 16499, Gyeonggi Do, South Korea; Kyungpook Natl Univ, Sch Mat Sci & Engn, Daegu 41566, South Korea; Jeonbuk Natl Univ, Hydrogen & Fuel Cell Res Ctr, Convers Engn Grad Sch, Dept Energy Storage, Jeonju 54896, Jeonbuk, South Korea; Daegu Ctr, Korea Basic Sci Inst, Daegu 41566, South Korea; Ajou Univ, Dept Mat Sci & Engn, Suwon 16499, Gyeonggi Do, South Korea | Fatti, Giulio/ABE-4757-2020; Park, Kwiil/LKN-9445-2024; Jeong, Chang Kyu/ADT-8127-2022; Dini, Daniele/H-8335-2013; Na, Yujin/LFT-4103-2024 | 57203416107; 57193010824; 56924395400; 57188594346; 57566141800; 55961876600; 58565882000; 57217094858; 35280874200; 48461004400; 9043849700 | g.fatti18@imperial.ac.uk;hko@kicet.re.kr;kipark@knu.ac.kr;csb@ajou.ac.kr; | ADVANCED ELECTRONIC MATERIALS | ADV ELECTRON MATER | 2199-160X | 9 | 11 | SCIE | MATERIALS SCIENCE, MULTIDISCIPLINARY;NANOSCIENCE & NANOTECHNOLOGY;PHYSICS, APPLIED | 2023 | 5.3 | 23.7 | 0.74 | 2025-06-25 | 4 | 6 | DFT calculations; energy harvesting; polytetrafluoroethylene; triboelectrification; triboelectric nanogenerators | AB-INITIO; DEFLUORINATION; PERFORMANCE; POLYMERS; CHARGES | DFT calculations; energy harvesting; polytetrafluoroethylene; triboelectric nanogenerators; triboelectrification | Design for testability; Polytetrafluoroethylenes; Triboelectricity; Back flow; Defluorination; Design strategies; DFT calculation; Ionic defects; Model predictive; Nanogenerators; Rational design; Triboelectric nanogenerator; Triboelectrification; Nanogenerators | English | 2023 | 2023-11 | 10.1002/aelm.202300333 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Conditionally positive definite unilateral weighted shifts | In a recent paper [15], Hilbert space operators T with the property that each sequence of the form {IITnhII2}infinity n=0 is con-ditionally positive definite in a semigroup sense were intro-duced. In the present paper, this line of research is continued in depth in the case of unilateral weighted shifts. The condi-tional positive definiteness of unilateral weighted shifts is char-acterized in terms of formal moment sequences. The descrip-tion of the representing triplet, the main object canonically associated with such operators, is provided. The backward ex-tension problem for conditionally positive definite unilateral weighted shifts is solved, revealing a new feature that does not appear in the case of other operator classes. Finally, the flatness problem in this context is discussed with emphases on unexpected differences from the analogous problem for sub-normal unilateral weighted shifts. (c) 2023 Elsevier Inc. All rights reserved. | Jablonski, Zenon Jan; Jung, Il Bong; Lee, Eun Young; Stochel, Jan | Uniwersytet Jagiellonski, Inst Matemat, Ul Lojasiewicza 6, PL-30348 Krakow, Poland; Kyungpook Natl Univ, Dept Math, Daegu 41566, South Korea | 6602624635; 7102964485; 55371789400; 6602273956 | Zenon.Jablonski@im.uj.edu.pl;ibjung@knu.ac.kr;eunyounglee@knu.ac.kr;Jan.Stochel@im.uj.edu.pl; | LINEAR ALGEBRA AND ITS APPLICATIONS | LINEAR ALGEBRA APPL | 0024-3795 | 1873-1856 | 671 | SCIE | MATHEMATICS, APPLIED;MATHEMATICS | 2023 | 1 | 23.8 | 0.85 | 2025-06-25 | 2 | 2 | Weighted shift operator; Conditionally positive definite operator; Backward extension; Flatness | M-ISOMETRIC TRANSFORMATIONS | Backward extension; Conditionally positive definite operator; Flatness; Weighted shift operator | Backward extension; Conditionally positive definite operator; Flatness; Positive definite; Positive definiteness; Property; Semigroups; Shift operators; Space operators; Weighted shift operator; Linear algebra | English | 2023 | 2023-08-15 | 10.1016/j.laa.2023.04.014 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Cyclic structure Jacobi semi-symmetric real hypersurfaces in the complex quadric | First we introduce the notion of cyclic structure Jacobi semi-symmetric real hypersurfaces in the complex quadric Q(m) = SOm+2/SOmSO2. Next we give a classification of real hypersurfaces in the complex quadric Qm = SOm+2/SOmSO2 with cyclic structure Jacobi semi-symmetric tensor according to the (sic)-principal or (sic)-isotropic unit normal vector field. | Suh, Young Jin | Kyungpook Natl Univ, Dept Math, Daegu 41566, South Korea; Kyungpook Natl Univ, RIRCM, Daegu 41566, South Korea | 7202260479 | yjsuh@knu.ac.kr; | MATHEMATISCHE ZEITSCHRIFT | MATH Z | 0025-5874 | 1432-1823 | 303 | 2 | SCIE | MATHEMATICS | 2023 | 1 | 23.8 | 0.4 | 2025-06-25 | 0 | 1 | Cyclic structure Jacobi semi-symmetric; (sic)-isotropic; (sic)-principal; Kahler structure; Complex conjugation; complex quadric | PROJECTIVE-SPACE; OPERATOR | A-isotropic; A-principal; Complex conjugation; complex quadric; Cyclic structure Jacobi semi-symmetric; Kähler structure | English | 2023 | 2023-02 | 10.1007/s00209-022-03201-6 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Sharp spectral bounds for the edge-connectivity of regular graphs | Let ),2(G) and K '(G) be the second largest eigenvalue and the edge-connectivity of a graph G, respectively. Let r be a positive integer at least 3. For t = 1 or 2, Cioaba gave sharp upper bounds for ),2(G) in an r-regular simple graph G to guarantee that K '(G) > t+1. In this paper, we resolve this question for all t > 3; if G is an r-regular simple graph with ),2(G) t + 1, and for odd t, if G is an r-regular simple , then K '(G) > t + 1. 2 (c) 2023 Elsevier Ltd. All rights reserved. | Suil, O.; Park, Jeong Rye; Park, Jongyook; Zhang, Wenqian | State Univ New York Korea, Dept Appl Math & Stat, Incheon 21985, South Korea; Kyungpook Natl Univ, Dept Math, Daegu 41566, South Korea; Shandong Univ Technol, Sch Math & Stat, Zibo 255049, Peoples R China | Park, Jeong Rye/MDS-8129-2025; O, Suil/AGE-3425-2022 | 57957000500; 56471031400; 36091826300; 57207736642 | suil.o@sunykorea.ac.kr;parkjr@knu.ac.kr;jongyook@knu.ac.kr;zhangwq@pku.edu.cn; | EUROPEAN JOURNAL OF COMBINATORICS | EUR J COMBIN | 0195-6698 | 1095-9971 | 110 | SCIE | MATHEMATICS | 2023 | 1 | 23.8 | 2.08 | 2025-06-25 | 4 | 5 | ALGEBRAIC CONNECTIVITY | English | 2023 | 2023-05 | 10.1016/j.ejc.2023.103713 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||||
| ○ | ○ | Article | Some identities of degenerate higher-order Daehee polynomials based on A-umbral calculus | The degenerate versions of special polynomials and numbers, initiated by Carlitz, have regained the attention of some mathematicians by replacing the usual exponential function in the generating function of special polynomials with the degenerate exponential function. To study the relations between degenerate special polynomials, A-umbral calculus, an analogue of umbral calculus, is intensively applied to obtain related formulas for expressing one A-Sheffer polynomial in terms of other A-Sheffer polynomials. In this paper, we study the connection between degenerate higher-order Daehee polynomials and other degenerate type of special polynomials. We present explicit formulas for representations of the polynomials using A-umbral calculus and confirm the presented formulas between the degenerate higher-order Daehee polynomials and the degenerate Bernoulli polynomials, for example. Additionally, we investigate the pattern of the root distribution of these polynomials. | Kim, Dojin; Park, Sangbeom; Kwon, Jongkyum | Dongguk Univ, Dept Math, Seoul 04620, South Korea; Kyungpook Natl Univ, Dept Math, Daegu 41566, South Korea; Gyeongsang Natl Univ, Dept Math Educ, Jinju 52828, South Korea | Lee, Jun Young/CAI-2335-2022 | 57206696832; 57374873000; 55000770500 | mathkjk26@gnu.ac.kr; | ELECTRONIC RESEARCH ARCHIVE | ELECTRON RES ARCH | 2688-1594 | 31 | 6 | SCIE | MATHEMATICS | 2023 | 1 | 23.8 | 0 | 2025-06-25 | 0 | 0 | generating function; A-umbral calculus; A-Sheffer polynomial; special polynomial; degenerate higher-order Daehee polynomial | (Formula presented)-Sheffer polynomial; (Formula presented)-umbral calculus; degenerate higher-order Daehee polynomial; generating function; special polynomial | English | 2023 | 2023 | 10.3934/era.2023155 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Some identities of degenerate multi-poly-Changhee polynomials and numbers | Recently, many researchers studied the degenerate multi-special polynomials as degenerate versions of the multi-special polynomials and obtained some identities and properties of the those polynomials. The aim of this paper was to introduce the degenerate multi-poly-Changhee polynomials arising from multiple logarithms and investigate some interesting identities and properties of these polynomials that determine the relationship between multi-poly-Changhee polynomials, the Stirling numbers of the second kind, degenerate Stirling numbers of the first kind and falling factorial sequences. In addition, we investigated the phenomenon of scattering the zeros of these polynomials. | Yun, Sang Jo; Park, Sangbeom; Park, Jin-Woo; Kwon, Jongkyum | Dong A Univ, Dept Math, Busan 604714, South Korea; Kyungpook Natl Univ, Dept Math, Daegu 41566, South Korea; Daegu Univ, Dept Math Educ, Gyongsan 38453, South Korea; Gyeongsang Natl Univ, Dept Math Educ, Jinju 52828, South Korea | Lee, Jun Young/CAI-2335-2022 | 55261263100; 57374873000; 56135574800; 55000770500 | a0417001@daegu.ac.kr;mathkjk26@gnu.ac.kr; | ELECTRONIC RESEARCH ARCHIVE | ELECTRON RES ARCH | 2688-1594 | 31 | 12 | SCIE | MATHEMATICS | 2023 | 1 | 23.8 | 0 | 2025-06-25 | 0 | 0 | degenerate multi-poly-Changhee polynomials; multiple logarithm; the zeros of polynomials | degenerate multi-poly-Changhee polynomials; multiple logarithm; the zeros of polynomials | English | 2023 | 2023 | 10.3934/era.2023367 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | AST-001 Improves Social Deficits and Restores Dopamine Neuron Activity in a Mouse Model of Autism | Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder characterized by impaired social communication and social interaction, restricted and repetitive behavior, and interests. The core symptoms of ASD are associated with deficits in mesocorticolimbic dopamine pathways that project from the ventral tegmental area (VTA) to the nucleus accumbens (NAc) and medial prefrontal cortex (mPFC). AST-001 is an investigational product currently in a phase 3 clinical trial for treating the core symptoms of ASD, with L-serine as the API (active pharmaceutical ingredient). Because the causes of ASD are extremely heterogeneous, a single genetic ASD model cannot represent all autism models. In this paper, we used the VPA-exposed model, which is more general and widely used than a single genetic model, but this is also one of the animal models of autism. Herein, we conducted experiments to demonstrate the efficacy of AST-001 as L-Serine that alters the regulation of the firing rate in dopamine neurons by inhibiting small conductance Ca2+-activated K+ channels (SK channels). Through these actions, AST-001 improved sociability and social novelty by rescuing the intrinsic excitabilities of dopamine neurons in VPA-exposed ASD mouse models that showed ASD-related behavioral abnormalities. It is thought that this effect of improving social deficits in VPA-exposed ASD mouse models is due to AST-001 normalizing aberrant SK channel activities that slowed VTA dopamine neuron firing. Overall, these findings suggest that AST-001 may be a potential therapeutic agent for ASD patients, and that its mechanism of action may involve the regulation of dopamine neuron activity and the improvement of social interaction. | Um, Ki Bum; Kwak, Soyoung; Cheon, Sun-Ha; Kim, JuHyun; Hwang, Su-Kyeong | Astrogen Inc, 440 Hyeoksin Daero, Daegu 41072, South Korea; Kyungpook Natl Univ, Sch Med, Dept Pediat, Daegu 41944, South Korea | 42361831700; 59436376500; 58776377800; 58776963500; 37761570400 | kb_um@astrogen.co.kr;ksy1432@astrogen.co.kr;skhwang@astrogen.co.kr; | BIOMEDICINES | BIOMEDICINES | 2227-9059 | 11 | 12 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY;MEDICINE, RESEARCH & EXPERIMENTAL;PHARMACOLOGY & PHARMACY | 2023 | 3.9 | 23.9 | 0.5 | 2025-06-25 | 4 | 3 | ASD; social interaction; dopaminergic neuron; pacemaking; calcium-activated potassium channel; valproic acid | L-SERINE; SPECTRUM DISORDER; ANXIETY | ASD; calcium-activated potassium channel; dopaminergic neuron; pacemaking; social interaction; valproic acid | English | 2023 | 2023-12 | 10.3390/biomedicines11123283 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Differential Regulation of Intracisternally Injected Angiotensin II-Induced Mechanical Allodynia and Thermal Hyperalgesia in Rats | The present study examined the underlying mechanisms of mechanical allodynia and thermal hyperalgesia induced by the intracisternal injection of angiotensin (Ang) II. Intracisternal Ang II injection decreased the air puff threshold and head withdrawal latency. To determine the operative receptors for each distinct type of pain behavior, we intracisternally injected Ang II receptor antagonists 2 h after Ang II injection. Losartan, an Ang II type 1 receptor (AT1R) antagonist, alleviated mechanical allodynia. Conversely, PD123319, an Ang II type 1 receptor (AT2R) antagonist, blocked only thermal hyperalgesia. Immunofluorescence analyses revealed the co-localization of AT1R with the astrocyte marker GFAP in the trigeminal subnucleus caudalis and co-localization of AT2R with CGRP-positive neurons in the trigeminal ganglion. Intracisternal pretreatment with minocycline, a microglial inhibitor, did not affect Ang II-induced mechanical allodynia, whereas L-alpha-aminoadipate, an astrocyte inhibitor, significantly inhibited Ang II-induced mechanical allodynia. Furthermore, subcutaneous pretreatment with botulinum toxin type A significantly alleviated Ang II-induced thermal hyperalgesia, but not Ang II-induced mechanical allodynia. These results indicate that central Ang II-induced nociception is differentially regulated by AT1R and AT2R. Thus, distinct therapeutic targets must be regulated to overcome pain symptoms caused by multiple underlying mechanisms. | Park, Ki-Don; Son, Jo-Young; Kim, Hak-Kyun; Kim, Yu-Mi; Ju, Jin-Sook; Jo, Min-Jeong; Park, Min-Kyoung; Lee, Min-Kyung; Ahn, Dong-Kuk | Kyungpook Natl Univ, Sch Dent, Dept Oral Physiol, Daegu 41940, South Korea; Kyung Woon Univ, Dept Dent Hyg, Gumi 39160, South Korea; Dong Eui Univ, Dept Dent Hyg, Busan 47340, South Korea | 56420803100; 57201998311; 58777369200; 57816812300; 7202751199; 58777770200; 36185933400; 57157512400; 7202706889 | turtles1@hanmail.net;n-violetjy@nate.com;hakyuna@hanmail.net;boboatom@naver.com;jsju@knu.ac.kr;dmvvv3@naver.com;bukimin@hanmail.net;lmk849@deu.ac.kr;dkahn@knu.ac.kr; | BIOMEDICINES | BIOMEDICINES | 2227-9059 | 11 | 12 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY;MEDICINE, RESEARCH & EXPERIMENTAL;PHARMACOLOGY & PHARMACY | 2023 | 3.9 | 23.9 | 0 | 2025-06-25 | 0 | 0 | angiotensin II; angiotensin II type 1 receptor; angiotensin II type 2 receptor; astrocytes; botulinum toxin type A; mechanical allodynia; thermal hyperalgesia | PERIAQUEDUCTAL GRAY-MATTER; TYPE-2 RECEPTOR; NEUROPATHIC PAIN; SYSTEM; ANTAGONIST; ACTIVATION; MODEL; INVOLVEMENT; ASTROCYTES; BLOCKADE | angiotensin II; angiotensin II type 1 receptor; angiotensin II type 2 receptor; astrocytes; botulinum toxin type A; mechanical allodynia; thermal hyperalgesia | English | 2023 | 2023-12 | 10.3390/biomedicines11123279 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Efficacy of Combined Initial Treatment of Methotrexate with Infliximab in Pediatric Crohn's Disease: A Pilot Study | Background: The combination of antitumor necrosis factor-alpha (TNF-& alpha;) agents with immunomodulators (IMMs) is a common treatment for pediatric Crohn's disease (CD). Although methotrexate (MTX) can be a first-line medication as an IMM, most clinicians in real-life practice, especially in South Korea, are more familiar with thiopurines. This study aimed to compare the efficacy and immunogenicity of MTX and azathioprine (AZA) as concurrent therapies for pediatric CD. Methods: In this pilot study, 29 newly diagnosed pediatric patients with moderate-to-severe CD were randomized to receive either MTX (n = 15) (15 mg/body surface area (BSA) per week) or oral AZA (n = 14) (0.5 mg/kg per day) in combination with Infliximab (IFX). The primary outcomes were the proportion of patients in endoscopic, biochemical, and transmural remission after 14 and 54 weeks of IFX therapy. The trough levels (TLs) of IFX and anti-drug antibody (ADA) levels were also compared. Results: Among the 29 patients, there were no significant differences in the biochemical (p = 1.0 at week 14, p = 0.45 at week 54), endoscopic (p = 0.968 at week 14, p = 0.05 at week 54), or transmural (p = 0.103 at week 54) remission rates between the two medications during the concurrent therapy. Additionally, the trends in the IFX trough and ADA levels over time during the treatments were similar for both medications, with no significant differences (p = 0.686, p = 0.389, respectively). Conclusion: The MTX showed comparable efficacy to the AZA in pediatric CD patients with moderate-to-severe disease. This effectively maintained adequate IFX levels and reduced ADA production. Therefore, although additional large-scale clinical trials are needed, this study demonstrated that either MTX or AZA can be selected as IMMs in the concurrent treatment of pediatric CD, depending on individual medical institutions' circumstances. | Kim, Yoon-Zi; Kang, Ben; Kim, Eun-Sil; Kwon, Yiyoung; Choe, Yon-Ho; Kim, Mi-Jin | Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Pediat, Seoul 06351, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Sch Med, Dept Pediat, Daegu 41944, South Korea; Sungkyunkwan Univ, Dept Pediat, Samsung Med Ctr, Sch Med, Seoul 03181, South Korea; Inha Univ, Inha Univ Hosp, Dept Pediat, Sch Med, Incheon 22188, South Korea | ; Kim, Mi Jin/GXH-9639-2022; 康, 奔/JMQ-0812-2023 | 57942981200; 57194823199; 57205500267; 57211905573; 21333712100; 56638815200 | na202@inha.ac.kr;yonho.choe@samsung.com;mijin1217.kim@samsung.com; | BIOMEDICINES | BIOMEDICINES | 2227-9059 | 11 | 9 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY;MEDICINE, RESEARCH & EXPERIMENTAL;PHARMACOLOGY & PHARMACY | 2023 | 3.9 | 23.9 | 0.5 | 2025-06-25 | 2 | 3 | pediatric Crohn's disease; immunogenicity; azathioprine; methotrexate; trough level of anti-TNF agent; anti-drug antibody; immunomodulatory | INFLAMMATORY-BOWEL-DISEASE; LOW-DOSE AZATHIOPRINE; ANTI-DRUG ANTIBODIES; MAINTAINING REMISSION; COMBINATION THERAPY; SERUM INFLIXIMAB; CHINESE PATIENTS; PRIOR FAILURE; IBD; IMMUNOMODULATOR | anti-drug antibody; azathioprine; immunogenicity; immunomodulatory; methotrexate; pediatric Crohn’s disease; trough level of anti-TNF agent | English | 2023 | 2023-09 | 10.3390/biomedicines11092575 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Microwave-assisted rapid synthesize of cadmium-thallium mixed fluoride hydrate complex and its physiochemical properties | Herein we report a facile and rapid, cost-effective microwave-assisted synthesis of mixed cadmium-thallium fluoride hydrate compound using a homemade vessel with a special protective outer container. The physico-chemical properties of the prepared compound were investigated by several characterization techniques. Single crystal X-ray diffraction measurement was performed to investigate the crystal structure of the prepared com-pound. The XEOL intensity shows a good linear response as a function of the delivered X-ray dose, which in-dicates that this material can be highly desirable for radiation detection applications. The fitting of scintillation decay kinetic from a241Am & alpha;-radiation source, shows the fastest decay time constant of 40 ns (16%) with medium and slow components of 380 ns (72%) and 1.5 & mu;s (12%) at room temperature. The pulse height spectrum shows the photopeak of & alpha;-particles produced by the 241Am radiation source at 5.48 MeV. | Daniel, D. Joseph; Prabhu, Subbaiah Muthu; Kim, H. J. | Kyungpook Natl Univ, Ctr High energy Phys, Daegu 41566, South Korea; VIT AP Univ, Sch Adv Sci, Dept Chem, Vijayawada 522237, Andhra Prades, India | Kim, Hong Joo/AAE-1178-2022; Subbaiah, Muthu/E-3347-2016 | 35319662800; 7101753878; 59051568100 | hongjoo@knu.ac.kr; | OPTICAL MATERIALS | OPT MATER | 0925-3467 | 1873-1252 | 141 | SCIE | MATERIALS SCIENCE, MULTIDISCIPLINARY;OPTICS | 2023 | 3.8 | 23.9 | 0.15 | 2025-06-25 | 1 | 1 | Mixed fluorides; Microwave synthesis; X-ray luminescence; Decay time | CRYSTAL-STRUCTURE; COORDINATION POLYMER; HYDROGEN; PHASE; GROWTH; NANOPARTICLES; TRANSITION; CHEMISTRY | Decay time; Microwave synthesis; Mixed fluorides; X-ray luminescence | Cadmium compounds; Cost effectiveness; Crystal structure; Fluorine compounds; Hydrates; Physicochemical properties; Single crystals; Thallium compounds; Cost effective; Decay time; Hydrate complexes; Microwave assisted synthesis; Microwave synthesis; Microwave-assisted; Mixed fluoride; Physio-chemical properties; Radiation source; X ray luminescence; Hydration | English | 2023 | 2023-07 | 10.1016/j.optmat.2023.113942 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Review | Pathophysiological Role of Microglial Activation Induced by Blood-Borne Proteins in Alzheimer's Disease | The blood-brain barrier (BBB) restricts entry of neurotoxic plasma components, blood cells, and pathogens into the brain, leading to proper neuronal functioning. BBB impairment leads to blood-borne protein infiltration such as prothrombin, thrombin, prothrombin kringle-2, fibrinogen, fibrin, and other harmful substances. Thus, microglial activation and release of pro-inflammatory mediators commence, resulting in neuronal damage and leading to impaired cognition via neuroinflammatory responses, which are important features observed in the brain of Alzheimer's disease (AD) patients. Moreover, these blood-borne proteins cluster with the amyloid beta plaque in the brain, exacerbating microglial activation, neuroinflammation, tau phosphorylation, and oxidative stress. These mechanisms work in concert and reinforce each other, contributing to the typical pathological changes in AD in the brain. Therefore, the identification of blood-borne proteins and the mechanisms involved in microglial activation and neuroinflammatory damage can be a promising therapeutic strategy for AD prevention. In this article, we review the current knowledge regarding the mechanisms of microglial activation-mediated neuroinflammation caused by the influx of blood-borne proteins into the brain via BBB disruption. Subsequently, the mechanisms of drugs that inhibit blood-borne proteins, as a potential therapeutic approach for AD, along with the limitations and potential challenges of these approaches, are also summarized. | Kim, Sehwan; Sharma, Chanchal; Jung, Un Ju; Kim, Sang Ryong | Kyungpook Natl Univ, Sch Life Sci, Daegu 41566, South Korea; Kyungpook Natl Univ, Brain Sci & Engn Inst, Daegu 41944, South Korea; Kyungpook Natl Univ, BK21 FOUR KNU Creat Biores Grp, Daegu 41566, South Korea; Pukyong Natl Univ, Dept Food Sci & Nutr, Busan 48513, South Korea | 57193232250; 57193577728; 7007119425; 56486163800 | arputa@naver.com;chanchalmrt@gmail.com;jungunju@naver.com;srk75@knu.ac.kr; | BIOMEDICINES | BIOMEDICINES | 2227-9059 | 11 | 5 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY;MEDICINE, RESEARCH & EXPERIMENTAL;PHARMACOLOGY & PHARMACY | 2023 | 3.9 | 23.9 | 0.81 | 2025-06-25 | 9 | 13 | Alzheimer's disease; microglia; neuroinflammation; neurodegeneration; blood-brain barrier; blood-borne protein | BRAIN-BARRIER PERMEABILITY; NEURONS IN-VIVO; AMYLOID-BETA; DOPAMINERGIC-NEURONS; CEREBROSPINAL-FLUID; KRINGLE-2 DOMAIN; OXIDATIVE STRESS; TIGHT JUNCTIONS; UP-REGULATION; MOUSE MODEL | Alzheimer’s disease; blood-borne protein; blood–brain barrier; microglia; neurodegeneration; neuroinflammation | English | 2023 | 2023-05-07 | 10.3390/biomedicines11051383 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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