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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Article | KMTNet Nearby Galaxy Survey: Overview and Survey Description | Recently, there has been increasing demand for deep imaging surveys to investigate the history of the mass assembly of galaxies in detail by examining the remnants of mergers and accretions, both of which have very low surface brightness (LSB). In addition, the nature of star formation in LSB regions, such as galaxy outer disks, is also an intriguing topic in terms of understanding the physical mechanisms of disk evolution. To address these issues, this study conducted a survey project, called the Korea Microlensing Telescope Network Nearby Galaxy Survey, to construct a deep imaging data set of nearby galaxies in the southern hemisphere. It provides deep and wide-field images with a field of view of similar to 12 deg(2) for 13 nearby galaxies drawn from the Carnegie-Irvine Galaxy Survey catalog in optical broad bands (BRI) and an H alpha narrow band. Through a dedicated data reduction, the surface brightness limit in 10 '' x 10 '' boxes was found to reach as deep as mu (1 sigma ) similar to 29-31 mag arcsec(-2) in the optical broad bands and f (1 sigma ) similar to 1-2 x 10(-18) erg s(-1) cm(-2) arcsec(-2) in the H alpha narrow band. To conclude the paper, several possible scientific applications for this data set are described. | Byun, Woowon; Sheen, Yun-Kyeong; Seon, Kwang-, II; Ho, Luis C.; Lee, Joon Hyeop; Jeong, Hyunjin; Kim, Sang Chul; Park, Byeong-Gon; Lee, Yongseok; Cha, Sang-Mok; Kim, Minjin | Korea Astron & Space Sci Inst, Daejeon 34055, South Korea; Univ Sci & Technol, Daejeon 34113, South Korea; Peking Univ, Kavli Inst Astron & Astrophys, Beijing 100871, Peoples R China; Peking Univ, Sch Phys, Dept Astron, Beijing 100871, Peoples R China; Kyung Hee Univ, Sch Space Res, Yongin 17104, Kyeonggi, South Korea; Kyungpook Natl Univ, Dept Astron & Atmospher Sci, Daegu 41566, South Korea | LEE, YONGSEOK/AAF-3965-2020; Kim, Minjin/AAU-9910-2020 | 57216758314; 23568407100; 6603554666; 57225302746; 57214829257; 16202920600; 26659735200; 7402834628; 36068040300; 13610036800; 56898213300 | mkim@knu.ac.kr; | PUBLICATIONS OF THE ASTRONOMICAL SOCIETY OF THE PACIFIC | PUBL ASTRON SOC PAC | 0004-6280 | 1538-3873 | 134 | 1039 | SCIE | ASTRONOMY & ASTROPHYSICS | 2022 | 3.5 | 31.2 | 0.17 | 2025-06-25 | 2 | 2 | EXTENDED ULTRAVIOLET DISK; STAR-FORMATION RATE; INITIAL MASS FUNCTION; EXTREME OUTER DISK; H-ALPHA; FORMING GALAXIES; DWARF GALAXIES; STELLAR HALOS; LOCAL VOLUME; DEEP | English | 2022 | 2022-09-01 | 10.1088/1538-3873/ac8ed4 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Optically Isotropic Liquid Crystal Mode Templated by Nanoporous Breath Figure Membrane | In this study, a printing-based scalable method is proposed for the higher density of a liquid crystal (LC) nanodroplet structure suitable for the optically isotropic LC mode where the LC nanodomains are accurately templated by a nanoporous breath figure (BF) membrane. The highly porous BF polymeric template structure is reliably obtained by utilizing self-structured packing effects of the silica nanospheres achieved by doctor blade coating. A nanocomposite film with densely packed silica nanospheres encapsulated by the UV-crosslinked polymer matrix is made by controlling the blade coating velocity and blade gap conditions. This provides a higher LC fill-factor condition of the optically isotropic nanodroplet LC (OI-NDLC) mode with filling the LCs into the nanopores obtained after selective silica etching. The OI-NDLC structure templated by the nanoporous BF membrane made with the silica nanospheres of 300 nm can effectively resolve the scattering-induced optical loss and depolarization issues observable in the OI-NDLC mode prepared by conventional phase separation approaches due to the sufficiently reduced LC droplet size. The structure exhibits a much-improved light leakage level in the field-off optically isotropic state, a higher transmittance level as the field-induced Kerr operation, and resultant improved contrast ratio properties. | Shin, Young-Chul; Park, Ji-Sub; Joo, Kyung-Il; Kim, Hyun Gyu; Manda, Ramesh; Choi, Jun-Chan; Kim, Hak-Rin | Kyungpook Natl Univ, Sch Elect & Elect Engn, Daegu 41566, South Korea; LG Display Co Ltd, Paju 10845, Gyeonggi Do, South Korea; Kyungpook Natl Univ, Sch Elect Engn, Daegu 41566, South Korea; Korea Photon Technol Inst, Spatial Opt Informat Res Ctr, Gwangju 61007, South Korea | Manda, Ramesh/D-7315-2015; Kim, Hak-Rin/T-1897-2019 | 57195222983; 39262218000; 36680185400; 57191720622; 57194193627; 57033068900; 7410124944 | rineey@knu.ac.kr; | ADVANCED MATERIALS INTERFACES | ADV MATER INTERFACES | 2196-7350 | 9 | 7 | SCIE | CHEMISTRY, MULTIDISCIPLINARY;MATERIALS SCIENCE, MULTIDISCIPLINARY | 2022 | 5.4 | 31.2 | 0.58 | 2025-06-25 | 7 | 7 | depolarization effects; displays; liquid crystals; nanodroplet liquid crystals; optically isotropic mode | INDUCED PHASE-SEPARATION; HIGH-PERFORMANCE; VIEWING-ANGLE; MICROLENS ARRAYS; PRETILT ANGLE; BLUE-PHASE; POLARIZATION; DROPLETS; FILM; DEPOLARIZATION | depolarization effects; displays; liquid crystals; nanodroplet liquid crystals; optically isotropic mode | Coatings; Crystal structure; Liquid crystals; Nanocomposite films; Nanospheres; Phase separation; Polymer matrix composites; Scalability; Breath figures; Isotropics; Liquid-crystals; Nano-droplets; Nano-porous; Nanodomain; Optically isotropic liquid crystal; Scalable methods; Silica nanospheres; Templated; Silica | English | 2022 | 2022-03 | 10.1002/admi.202101919 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Overexpression of acdS in Petunia hybrida Improved Flower Longevity and Cadmium-Stress Tolerance by Reducing Ethylene Production in Floral and Vegetative Tissues | The role of acdS, which encodes the 1-aminocyclopropane-1-carboxylic acid (ACC) deaminase enzyme, in extending flower longevity and improving tolerance to cadmium (Cd) stress was assessed using transgenic Petunia hybrida cv. 'Mirage Rose' overexpressing acdS and wild-type (WT) plants. The overexpression of acdS reduced ethylene production in floral tissue via suppression of ethylene-related genes and improved flower longevity, approximately 2 to 4 days longer than WT flowers. Under Cd stress, acdS significantly reduced Cd-induced ethylene production in vegetable tissues of transgenic plants through suppression of ethylene-related genes. This resulted in a lower accumulation of ethylene-induced reactive oxygen species (ROS) in the transgenic plants than in WT plants. In addition, expression of the genes involved in the activities of antioxidant and proline synthesis as well as the metal chelation process was also higher in the former than in the latter. Moreover, Cd accumulation was significantly higher in WT plants than in the transgenic plants. These results are linked to the greater tolerance of transgenic plants to Cd stress than the WT plants, which was determined based on plant growth and physiological performance. These results highlight the potential applicability of using acdS to extend flower longevity of ornamental bedding plants and also reveal the mechanism by which acdS improves Cd-stress tolerance. We suggest that acdS overexpression in plants can extend flower longevity and also help reduce the negative impact of Cd-induced ethylene on plant growth when the plants are unavoidably cultivated in Cd-contaminated soil. | Naing, Aung Htay; Campol, Jova Riza; Chung, Mi Young; Kim, Chang Kil | Kyungpook Natl Univ, Dept Hort Sci, Daegu 41566, South Korea; Sunchon Natl Univ, Dept Agr Educ, 413 Jungangno, Sunchon 540950, Jeonnam, South Korea | ; Naing, Aung Htay/AAF-4277-2019 | 37112768100; 57486378900; 24821361600; 7409880701 | aunghtaynaing2005@gmail.com;ckkim@knu.ac.kr;ahnaing@knu.ac.kr; | CELLS | CELLS-BASEL | 2073-4409 | 11 | 20 | SCIE | CELL BIOLOGY | 2022 | 6 | 31.2 | 0.44 | 2025-06-25 | 7 | 7 | ACC deaminase; cadmium (Cd) stress; flower longevity; ethylene production; gene expression; plant growth; reactive oxygen species | 1-AMINOCYCLOPROPANE-1-CARBOXYLIC ACID DEAMINASE; ARABIDOPSIS PHYTOCHELATIN SYNTHASE; INDUCED OXIDATIVE STRESS; ACC DEAMINASE; PLANT-GROWTH; TRANSGENIC CANOLA; BACTERIAL ENZYME; ROOT ELONGATION; EXPRESSION; RESPONSES | ACC deaminase; cadmium (Cd) stress; ethylene production; flower longevity; gene expression; plant growth; reactive oxygen species | Antioxidants; Cadmium; Ethylenes; Flowers; Petunia; Plants, Genetically Modified; Proline; Reactive Oxygen Species; Soil; 1 aminocyclopropanecarboxylic acid; cadmium; ethylene; hydrogen peroxide; reactive oxygen metabolite; antioxidant; cadmium; ethylene; ethylene derivative; proline; Article; bioaccumulation; flower; gas chromatography; gene expression; nonhuman; Petunia; phenotype; physiological stress; plant growth; soil pollution; vegetative stage; flower; genetics; metabolism; soil; transgenic plant | English | 2022 | 2022-10 | 10.3390/cells11203197 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Performance Assessment of the KASI-Deep Rolling Imaging Fast-optics Telescope Pathfinder | In a ?CDM universe, most galaxies evolve by mergers and accretions, leaving faint and/or diffuse structures, such as tidal streams and stellar halos. Although these structures are a good indicator of galaxies' recent mass assembly history, they have the disadvantage of being difficult to observe due to their low surface brightness (LSB). To recover these LSB features by minimizing the photometric uncertainties introduced by the optical system, we developed a new optimized telescope named K-DRIFT pathfinder, adopting a linear astigmatism free-three mirror system. Thanks to the off-axis design, it is expected to avoid the loss and scattering of light on the optical path within the telescope. To assess the performance of this prototype telescope, we investigate the photometric depth and capability to identify LSB features. We find that the surface brightness limit reaches down to mu ( r,1 sigma ) similar to 28.5 mag arcsec(-2) in 10 '' x 10 '' boxes, enabling us to identify a single stellar stream to the east of NGC 5907. We also examine the characteristics of the point-spread function (PSF) and find that the PSF wing reaches a very low level. Still, however, some internal reflections appear within a radius of similar to 6 ' from the center of sources. Despite a relatively small aperture (0.3 m) and short integration time (2 hr), this result demonstrates that our telescope is highly efficient in LSB detection. | Byun, Woowon; Ko, Jongwan; Kim, Yunjong; Seon, Kwang-Il; Chang, Seunghyuk; Kim, Dohoon; Choi, Changsu; Chun, Sang-Hyun; Jeon, Young-Beom; Kim, Jae-Woo; Lee, Chung-Uk; Lee, Yongseok; Park, Hong Soo; Sung, Eon-Chang; Yoo, Jaewon; Lee, Gayoung; Lee, Hyoungkwon | Korea Astron & Space Sci Inst, Daejeon 34055, South Korea; Univ Sci & Technol, Daejeon 34113, South Korea; Ctr Integrated Smart Sensors, Daejeon 34141, South Korea; Green Opt Co Ltd, Cheongju 28126, South Korea; Kyung Hee Univ, Sch Space Res, Yongin 17104, Kyeonggi, South Korea; Kyungpook Natl Univ, Daegu 41566, South Korea; LeO SPACE Inc, Daejeon 34014, South Korea | Yoo, Jaewon/LMO-3911-2024; LEE, YONGSEOK/AAF-3965-2020 | 57216758314; 18434193800; 57203310827; 6603554666; 12759772300; 57295662700; 18433745100; 24823822200; 7201888508; 55983723600; 25723619800; 36068040300; 57203771728; 7006254254; 57289167300; 57846551600; 57219768348 | wbyun87@gmail.com;jwko@kasi.re.kr; | PUBLICATIONS OF THE ASTRONOMICAL SOCIETY OF THE PACIFIC | PUBL ASTRON SOC PAC | 0004-6280 | 1538-3873 | 134 | 1038 | SCIE | ASTRONOMY & ASTROPHYSICS | 2022 | 3.5 | 31.2 | 0.75 | 2025-06-25 | 4 | 9 | HIERARCHICAL GALAXY FORMATION; POINT-SPREAD FUNCTION; INTRACLUSTER LIGHT; ELLIPTIC GALAXIES; STELLAR; SUBSTRUCTURE; HALO; ACCRETION; FEATURES; ASTROPY | English | 2022 | 2022-08-01 | 10.1088/1538-3873/ac8500 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Review | Post-Translational Modifications of ATG4B in the Regulation of Autophagy | Autophagy plays a key role in eliminating and recycling cellular components in response to stress, including starvation. Dysregulation of autophagy is observed in various diseases, including neurodegenerative diseases, cancer, and diabetes. Autophagy is tightly regulated by autophagy-related (ATG) proteins. Autophagy-related 4 (ATG4) is the sole cysteine protease, and four homologs (ATG4A-D) have been identified in mammals. These proteins have two domains: catalytic and short fingers. ATG4 facilitates autophagy by promoting autophagosome maturation through reversible lipidation and delipidation of seven autophagy-related 8 (ATG8) homologs, including microtubule-associated protein 1-light chain 3 (LC3) and GABA type A receptor-associated protein (GABARAP). Each ATG4 homolog shows a preference for a specific ATG8 homolog. Post-translational modifications of ATG4, including phosphorylation/dephosphorylation, O-GlcNAcylation, oxidation, S-nitrosylation, ubiquitination, and proteolytic cleavage, regulate its activity and ATG8 processing, thus modulating its autophagic activity. We reviewed recent advances in our understanding of the effect of post-translational modification on the regulation, activity, and function of ATG4, the main protease that controls autophagy. | Park, Na Yeon; Jo, Doo Sin; Cho, Dong-Hyung | Kyungpook Natl Univ, Sch Life Sci, BK21 FOUR KNU Creat BioRes Grp, Daegu 41566, South Korea | ; Choi, Hye Rin/JDV-9065-2023 | 57190609826; 56335489800; 35093684400 | yeonie5613@gmail.com;doosinjo@gmail.com;dhcho@knu.ac.kr; | CELLS | CELLS-BASEL | 2073-4409 | 11 | 8 | SCIE | CELL BIOLOGY | 2022 | 6 | 31.2 | 1.69 | 2025-06-25 | 28 | 27 | ATG4; autophagy; post-translational modification | CASPASE CLEAVAGE; PHOSPHORYLATION; PROTEINS; DELIPIDATION; LC3 | ATG4; autophagy; post-translational modification | Animals; Autophagy; Autophagy-Related Protein 8 Family; Autophagy-Related Proteins; Mammals; Microtubule-Associated Proteins; Peptide Hydrolases; Protein Processing, Post-Translational; 6 phosphofructokinase; autophagy related 4b cysteine peptidase; autophagy related protein; autophagy related protein 4; autophagy related protein 8 family; calpain 1; caspase 3; phosphatidylethanolamine; sequestosome 1; serine threonine protein kinase ULK1; ubiquitin protein ligase E3; unclassified drug; autophagy related protein; autophagy related protein 8 family; microtubule associated protein; peptide hydrolase; Article; autophagosome; autophagy (cellular); cell maturation; dephosphorylation; diabetes mellitus; endoplasmic reticulum; endoplasmic reticulum stress; gene overexpression; glioblastoma; high throughput screening; human; innate immunity; liquid chromatography-mass spectrometry; luciferase assay; malignant neoplasm; nerve degeneration; nitrosylation; nonhuman; oxidative stress; physiological stress; protein degradation; protein dephosphorylation; protein expression; protein phosphorylation; protein processing; protein stability; ubiquitination; animal; autophagy; mammal; metabolism; physiology; protein processing | English | 2022 | 2022-04 | 10.3390/cells11081330 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Pragmatic role of microbial plant biostimulants in abiotic stress relief in crop plants | Abiotic stresses lead to excessive crop yield losses and are a major threat to agriculture. It is essential to equip crops with multi-stress tolerance to mitigate the adverse effects of abiotic stressors and meet the demands of the increasing global population. The association between plants and symbiotic microorganisms is involved in key functions at the ecosystem and plant levels, and the application of microbial plant biostimulants (MPBs) is a sustainable strategy to augment plant growth and productivity, even under abiotic stress conditions. Several different microorganisms can be used as MPBs to enhance plant growth and produce progressive and reproducible effects on crops. In the present review, we assessed the current knowledge on the use of MPBs, discuss the diversity and characteristics of MPBs, and provide a meticulous assessment of the possible applications of MPBs in abiotic stress relief in crops. | Ali, Sajid; Moon, Yong-Sun; Hamayun, Muhammad; Khan, Muhammad Aaqil; Bibi, Kalsoom; Lee, In-Jung | Yeungnam Univ, Dept Hort & Life Sci, Gyongsan, South Korea; Kyungpook Natl Univ, Dept Appl Biosci, Daegu, South Korea; Abdul Wali Khan Univ Mardan, Dept Bot, Mardan, Pakistan | ; Khan, Muhammad/ABB-9797-2021; Lee, In-Jung/GLS-0432-2022; Ali, Sajid/GLS-7322-2022; Hamayun, Muhammad/B-1694-2010 | 57214290889; 7203054923; 59297330100; 57188585606; 58447383500; 16425830900 | hangulmys@ynu.ac.kr;ijlee@knu.ac.kr; | JOURNAL OF PLANT INTERACTIONS | J PLANT INTERACT | 1742-9145 | 1742-9153 | 17 | 1 | SCIE | PLANT SCIENCES | 2022 | 3.2 | 31.2 | 2.88 | 2025-06-25 | 62 | 73 | Plant biostimulants; microbial biostimulants; abiotic stress; crops; sustainable agriculture | GROWTH-PROMOTING RHIZOBACTERIA; TOLERANCE; EXPRESSION; EXOPOLYSACCHARIDE; BACTERIA; FUNGI; ROOT | abiotic stress; crops; microbial biostimulants; Plant biostimulants; sustainable agriculture | English | 2022 | 2022-12-31 | 10.1080/17429145.2022.2091801 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Review | Regulation of Conidiogenesis in Aspergillus flavus | Aspergillus flavus is a representative fungal species in the Aspergillus section Flavi and has been used as a model system to gain insights into fungal development and toxin production. A. flavus has several adverse effects on humans, including the production of the most carcinogenic mycotoxin aflatoxins and causing aspergillosis in immune-compromised patients. In addition, A. flavus infection of crops results in economic losses due to yield loss and aflatoxin contamination. A. flavus is a saprophytic fungus that disperses in the ecosystem mainly by producing asexual spores (conidia), which also provide long-term survival in the harsh environmental conditions. Conidia are composed of the rodlet layer, cell wall, and melanin and are produced from an asexual specialized structure called the conidiophore. The production of conidiophores is tightly regulated by various regulators, including the central regulatory cascade composed of BrlA-AbaA-WetA, the fungi-specific velvet regulators, upstream regulators, and developmental repressors. In this review, we summarize the findings of a series of recent studies related to asexual development in A. flavus and provide insights for a better understanding of other fungal species in the section Flavi. | Cho, He-Jin; Son, Sung-Hun; Chen, Wanping; Son, Ye-Eun; Lee, Inhyung; Yu, Jae-Hyuk; Park, Hee-Soo | Kyungpook Natl Univ, Sch Food Sci & Biotechnol, Daegu 41566, South Korea; Univ Gottingen, Dept Mol Microbiol & Genet, D-37077 Gottingen, Germany; Kookmin Univ, Dept Bio & Fermentat Convergence Technol, Seoul 02707, South Korea; Univ Wisconsin, Dept Bacteriol, Madison, WI 53706 USA; Konkuk Univ, Dept Syst Biotechnol, Seoul 05029, South Korea; Kyungpook Natl Univ, Dept Integrat Biol, Daegu 41566, South Korea | ; Yu, Jae-Hyuk/A-2343-2008; Park, Hee-Soo/AAC-6422-2019 | 57214721558; 57214091244; 55715932300; 57200513491; 55182595100; 7405531243; 15751448400 | phsoo97@knu.ac.kr; | CELLS | CELLS-BASEL | 2073-4409 | 11 | 18 | SCIE | CELL BIOLOGY | 2022 | 6 | 31.2 | 1.87 | 2025-06-25 | 48 | 51 | velvet; asexual development; BrlA; AbaA; WetA; Aspergillus flavus | CARBON CATABOLITE REPRESSION; TRANSCRIPTION FACTOR; ASEXUAL DEVELOPMENT; SEXUAL DEVELOPMENT; CONIDIOPHORE DEVELOPMENT; SECONDARY METABOLISM; CONIDIAL DEVELOPMENT; STRESS RESPONSES; GENE CLUSTERS; HYPHAL GROWTH | AbaA; asexual development; Aspergillus flavus; BrlA; velvet; WetA | Aflatoxins; Aspergillus flavus; Ecosystem; Fungal Proteins; Gene Expression Regulation, Fungal; Humans; Melanins; Spores, Fungal; aflatoxin B1; aflatoxin; fungal protein; melanin; aspergillosis; Aspergillus flavus; bacterial spore; biofilm; catabolite repression; cell wall; Conidiogenesis; conidium; contamination; DNA sequence; fungal development; fungus growth; gene expression; gene regulatory network; long term survival; metagenomics; mutational analysis; nonhuman; osmotic stress; oxidative stress; phenotype; repressor gene; Review; scanning electron microscopy; site directed mutagenesis; thin layer chromatography; transcription regulation; zinc finger motif; ecosystem; fungus spore; gene expression regulation; human; metabolism | English | 2022 | 2022-09 | 10.3390/cells11182796 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Review | RUNX Family in Hypoxic Microenvironment and Angiogenesis in Cancers | The tumor microenvironment (TME) is broadly implicated in tumorigenesis, as tumor cells interact with surrounding cells to influence the development and progression of the tumor. Blood vessels are a major component of the TME and are attributed to the creation of a hypoxic microenvironment, which is a common feature of advanced cancers and inflamed premalignant tissues. Runt-related transcription factor (RUNX) proteins, a transcription factor family of developmental master regulators, are involved in vital cellular processes such as differentiation, proliferation, cell lineage specification, and apoptosis. Furthermore, the RUNX family is involved in the regulation of various oncogenic processes and signaling pathways as well as tumor suppressive functions, suggesting that the RUNX family plays a strategic role in tumorigenesis. In this review, we have discussed the relevant findings that describe the crosstalk of the RUNX family with the hypoxic TME and tumor angiogenesis or with their signaling molecules in cancer development and progression. | Lee, You Mie | Kyungpook Natl Univ, Vessel Organ Interact Res Ctr, VOICE MRC, 80 Daehak Ro, Daegu 41566, South Korea; Kyungpook Natl Univ, Coll Pharm, Lab Mol Pathophysiol, 80 Daehak Ro, Daegu 41566, South Korea | Lee, Kyung-Soo/C-9016-2011 | 8230508600 | lym@knu.ac.kr; | CELLS | CELLS-BASEL | 2073-4409 | 11 | 19 | SCIE | CELL BIOLOGY | 2022 | 6 | 31.2 | 0.29 | 2025-06-25 | 7 | 8 | RUNX1; RUNX2; RUNX3; hypoxia; angiogenesis; tumor microenvironment; HIF | ENDOTHELIAL GROWTH-FACTOR; HEMATOPOIETIC STEM-CELLS; ACUTE MYELOID-LEUKEMIA; GASTRIC-CANCER; TRANSCRIPTION FACTOR; INDUCIBLE FACTOR-1-ALPHA; TUMOR-SUPPRESSOR; PROMOTES ANGIOGENESIS; FACTOR EXPRESSION; OXYGEN-TENSION | angiogenesis; HIF; hypoxia; RUNX1; RUNX2; RUNX3; tumor microenvironment | Carcinogenesis; Core Binding Factor alpha Subunits; Humans; Hypoxia; Morphogenesis; Neoplasms; Neovascularization, Pathologic; Transcription Factors; Tumor Microenvironment; baculoviral IAP repeat containing protein 5; bone sialoprotein; histone deacetylase 3; histone deacetylase 4; hypoxia inducible factor 1alpha; long untranslated RNA; nitric oxide; protein p53; small interfering RNA; transcription factor RUNX; transcription factor RUNX1; transcription factor RUNX2; vasculotropin; von Willebrand factor; transcription factor; transcription factor RUNX; angiogenesis; apoptosis; binding affinity; bone destruction; bone marrow cell; bone metastasis; cancer growth; cancer stem cell; carcinogenesis; cell cycle progression; cell differentiation; cell function; cell lineage; cell proliferation; chromatin immunoprecipitation; controlled study; DNA methylation; enchondral ossification; endothelial progenitor cell; epithelial mesenchymal transition; gene expression; gene overexpression; genetic transcription; glioblastoma; hemangioblast; histone acetylation; histone modification; human; hypoxia; immunoprecipitation; leukemogenesis; liver cell carcinoma; microarray analysis; protein expression; protein function; Review; signal transduction; transcription regulation; tumor associated leukocyte; tumor growth; tumor microenvironment; ubiquitination; carcinogenesis; genetics; metabolism; morphogenesis; neoplasm; neovascularization (pathology); physiology; tumor microenvironment | English | 2022 | 2022-10 | 10.3390/cells11193098 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Study on NaI(Tl) crystal at-35°C for dark matter detection | We present the response of a NaI(Tl) crystal in terms of the light yield and pulse shape characteristics at two different temperatures: 22 degrees C (room temperature) and -35 degrees C (low temperature). The light yield is measured using 59.54 keV gamma-rays from a Am-241 source relative to the mean charge of single photoelectrons. At the low temperature, we measure a 4.7 +/- 1.3% increase in the light yield compared to that at room temperature. A significantly increased decay time is also observed at the low temperature. The responses to nuclear recoil events are measured using neutrons from a Cf-252 source and compared to those to electron recoil events. The measured pulse shape discrimination (PSD) power of the NaI(Tl) crystal at the low temperature is found to be improved in the entire energy range studied because of the increased light yield and the different scintillation characteristics. We also find a 9.23 +/- 0.26% increased quenching factor of alpha-induced events, which is the light yield ratio of alpha recoil to electron recoil, at the low temperature. This supports the possibility of an increased quenching factor of the nuclear recoil events that are known to have similar processes of dark matter interaction. The increased light yield and the improved PSD power of nuclear recoil events enhance the sensitivity for dark matter detection via dark matter-nuclei interactions. | Lee, S. H.; Kim, G. S.; Kim, H. J.; Kim, K. W.; Lee, J. Y.; Lee, H. S. | Univ Sci & Technol UST, Daejeon 34113, South Korea; Inst Basic Sci IBS, Ctr Underground Phys, Daejeon 34126, South Korea; Kyungpook Natl Univ, Dept Phys, Daegu 41566, South Korea | Lee, Jooyoung/HTN-0335-2023; Kim, Dong Jin/JMR-1090-2023; Lee, Seunghyun/AAS-8066-2021; Kim, Hong Joo/AAE-1178-2022 | 57257129200; 57208178031; 59051568100; 57209988432; 57204797944; 56113238600 | kwkim@ibs.re.kr;hyunsulee@ibs.re.kr; | ASTROPARTICLE PHYSICS | ASTROPART PHYS | 0927-6505 | 1873-2852 | 141 | SCIE | ASTRONOMY & ASTROPHYSICS;PHYSICS, PARTICLES & FIELDS | 2022 | 3.5 | 31.2 | 0.65 | 2025-06-25 | 9 | 9 | Dark matter; NaI(Tl); Low temperature measurement | Dark matter; Low temperature measurement; NaI(Tl) | Crystals; Dark Matter; Galaxies; Gamma rays; Iodine compounds; Low temperature effects; Quenching; Sodium Iodide; Temperature measurement; Dark matter; Dark matter detection; Light pulse; Light yield; Low-temperature measurements; Lows-temperatures; Nuclear recoil; Power; Pulse shape discrimination; Quenching factors; Temperature | English | 2022 | 2022-08 | 10.1016/j.astropartphys.2022.102709 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Editorial Material | The Function of Glial Cells in the Neuroinflammatory and Neuroimmunological Responses | Afridi, Ruqayya; Tsuda, Makoto; Ryu, Hoon; Suk, Kyoungho | Kyungpook Natl Univ, Sch Med, Dept Pharmacol, Daegu 41944, South Korea; Kyungpook Natl Univ, Sch Med, Dept Biomed Sci, BK21 Plus KNU Biomed Convergence Program, Daegu 41944, South Korea; Kyushu Univ, Grad Sch Pharmaceut Sci, Dept Mol & Syst Pharmacol, Fukuoka 8128582, Japan; Korea Inst Sci & Technol KIST, Brain Sci Inst, Ctr Neurosci, Seoul 02792, South Korea; Kyungpook Natl Univ, Brain Sci & Engn Inst, Daegu 41944, South Korea | ; Ryu, Hoon/MCJ-9411-2025 | 57200759784; 35425824100; 7202277209; 7005114595 | r.afridi36@gmail.com;tsuda@phar.kyushu-u.ac.jp;hoonryu@kist.re.kr;ksuk@knu.ac.kr; | CELLS | CELLS-BASEL | 2073-4409 | 11 | 4 | SCIE | CELL BIOLOGY | 2022 | 6 | 31.2 | 4.2 | 2025-06-25 | 6 | 9 | Brain; Neuroglia; Neuroimmunomodulation; analgesic agent; lipopolysaccharide; succinate dehydrogenase; amyotrophic lateral sclerosis; astrocyte; cortical dysplasia; Editorial; frontotemporal dementia; gene interaction; glia cell; homeostasis; human; mass spectrometry; nerve degeneration; nervous system inflammation; pathology; spinal cord injury; synaptic transmission; brain; glia; immunomodulation; physiology | English | 2022 | 2022-02 | 10.3390/cells11040659 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||||
| ○ | ○ | Article | The Putative C2H2 Transcription Factor VadH Governs Development, Osmotic Stress Response, and Sterigmatocystin Production in Aspergillus nidulans | The VosA-VelB hetero-dimeric complex plays a pivotal role in regulating development and secondary metabolism in Aspergillus nidulans. In this work, we characterize a new VosA/VelB-activated gene called vadH, which is predicted to encode a 457-amino acid length protein containing four adjacent C2H2 zinc-finger domains. Mutational inactivation of vosA or velB led to reduced mRNA levels of vadH throughout the lifecycle, suggesting that VosA and VelB have a positive regulatory effect on the expression of vadH. The deletion of vadH resulted in decreased asexual development (conidiation) but elevated production of sexual fruiting bodies (cleistothecia), indicating that VadH balances asexual and sexual development in A. nidulans. Moreover, the vadH deletion mutant exhibited elevated susceptibility to hyperosmotic stress compared to wild type and showed elevated production of the mycotoxin sterigmatocystin (ST). Genome-wide expression analyses employing RNA-Seq have revealed that VadH is likely involved in regulating more genes and biological pathways in the developmental stages than those in the vegetative growth stage. The brlA, abaA, and wetA genes of the central regulatory pathway for conidiation are downregulated significantly in the vadH null mutant during asexual development. VadH also participates in regulating the genes, mat2, ppgA and lsdA, etc., related to sexual development, and some of the genes in the ST biosynthetic gene cluster. In summary, VadH is a putative transcription factor with four C2H2 finger domains and is involved in regulating asexual/sexual development, osmotic stress response, and ST production in A. nidulans. | Li, Xiaoyu; Zhao, Yanxia; Moon, Heungyun; Lim, Jieyin; Park, Hee-Soo; Liu, Zhiqiang; Yu, Jae-Hyuk | Univ Wisconsin, Dept Bacteriol, Madison, WI 53706 USA; Hainan Univ, Sch Life Sci, Haikou 570228, Peoples R China; Hainan Univ, Hlth Inst 1, Haikou 570228, Peoples R China; Jiangsu Normal Univ, Dept Life Sci, Key Lab Biotechnol Med Plants Jiangsu Prov, Xuzhou 221116, Peoples R China; Kyungpook Natl Univ, Sch Food Sci & Biotechnol, Daegu 41566, South Korea; Konkuk Univ, Dept Syst Biotechnol, Seoul 05029, South Korea | ; Park, Hee-Soo/AAC-6422-2019; Yu, Jae-Hyuk/A-2343-2008; Li, Xiaoyu/HSE-9827-2023; zhao, Yanxia/AAV-8756-2021 | 58026600200; 57218490027; 57204464970; 57214751656; 15751448400; 57191689712; 7405531243 | liuzhiqiang@hainanu.edu.cn;jyu1@wisc.edu; | CELLS | CELLS-BASEL | 2073-4409 | 11 | 24 | SCIE | CELL BIOLOGY | 2022 | 6 | 31.2 | 0.19 | 2025-06-25 | 3 | 3 | Aspergillus nidulans; velvet regulators; C2H2 transcription factors; development; sterigmatocystin; stress response | ASEXUAL SPORULATION; GENE; ENCODES; PCR | Aspergillus nidulans; C<sub>2</sub>H<sub>2</sub> transcription factors; development; sterigmatocystin; stress response; velvet regulators | Aspergillus nidulans; Fungal Proteins; Gene Expression Regulation, Fungal; Osmoregulation; Sterigmatocystin; Transcription Factors; messenger RNA; mycotoxin; sterigmatocystin; transcription factor; fungal protein; transcription factor; accuracy; adult; angiogenesis; apparent diffusion coefficient; Article; artificial neural network; astrocyte; astrocytoma; brain tumor; cell proliferation; chromoendoscopy; clinical outcome; controlled study; deep learning; developmental stage; diffusion weighted imaging; echo planar imaging; female; follow up; gene deletion; gene expression; glioblastoma; glioma; human; image analysis; image processing; immunohistochemistry; loss of function mutation; male; middle aged; multiparametric magnetic resonance imaging; neuroimaging; non invasive procedure; oligodendroglioma; osmotic stress; promoter region; quantitative analysis; retrospective study; RNA sequencing; T1 weighted imaging; T2 weighted imaging; transfer of learning; tumor growth; vegetative growth; Aspergillus nidulans; gene expression regulation; genetics; metabolism; osmoregulation | English | 2022 | 2022-12 | 10.3390/cells11243998 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Review | Transcriptional Regulation of Hepatic Autophagy by Nuclear Receptors | Autophagy is an adaptive self-eating process involved in degradation of various cellular components such as carbohydrates, lipids, proteins, and organelles. Its activity plays an essential role in tissue homeostasis and systemic metabolism in response to diverse challenges, including nutrient depletion, pathogen invasion, and accumulations of toxic materials. Therefore, autophagy dysfunctions are intimately associated with many human diseases such as cancer, neurodegeneration, obesity, diabetes, infection, and aging. Although its acute post-translational regulation is well described, recent studies have also shown that autophagy can be controlled at the transcriptional and post-transcriptional levels. Nuclear receptors (NRs) are in general ligand-dependent transcription factors consisting of 48 members in humans. These receptors extensively control transcription of a variety of genes involved in development, metabolism, and inflammation. In this review, we discuss the roles and mechanisms of NRs in an aspect of transcriptional regulation of hepatic autophagy, and how the NR-driven autophagy pathway can be harnessed to treat various liver diseases. | Kim, Eun Young; Lee, Jae Man | Kyungpook Natl Univ, Sch Med, Cell & Matrix Res Inst, Dept Biochem & Cell Biol, Daegu 41944, South Korea; Kyungpook Natl Univ, Dept Biomed Sci, BK21 4 KNU Biomed Convergence Program, Daegu 41944, South Korea | Lee, Jae/KFF-5361-2024; Kim, YoungHwan/B-2395-2013 | 57194632567; 47461355200 | key11@knu.ac.kr;jaemanlee@knu.ac.kr; | CELLS | CELLS-BASEL | 2073-4409 | 11 | 4 | SCIE | CELL BIOLOGY | 2022 | 6 | 31.2 | 0.4 | 2025-06-25 | 12 | 11 | autophagy; macroautophagy; nuclear receptor; liver | PROLIFERATOR-ACTIVATED RECEPTOR; FARNESOID X RECEPTOR; REV-ERB-ALPHA; NONALCOHOLIC FATTY LIVER; NEGATIVE FEEDBACK-REGULATION; BILE-ACID METABOLISM; VITAMIN-D-RECEPTOR; THYROID-HORMONE; PPAR-ALPHA; STELLATE CELLS | Autophagy; Liver; Macroautophagy; Nuclear receptor | Autophagy; Gene Expression Regulation; Homeostasis; Humans; Liver; Receptors, Cytoplasmic and Nuclear; adenosine triphosphate; autophagy related 13; beclin 1; cell nucleus receptor; death associated protein kinase 2; estrogen receptor alpha; farnesoid X receptor; fibroblast growth factor 19; fibroblast growth factor 21; glucocorticoid receptor; heat shock protein 90; hexokinase 2; hypoxia inducible factor 1alpha; mammalian target of rapamycin complex 1; peroxisome proliferator activated receptor alpha; phosphatidylinositol 3 phosphate; protein; sirtuin 1; unc 51 like kinase 1; unclassified drug; vacuolar protein sorting 15; cell receptor; adipogenesis; aging; amino acid metabolism; AMPK signaling; autophagosome; chromatin immunoprecipitation; degenerative disease; diabetes mellitus; drug metabolism; endoplasmic reticulum stress; genetic transcription; human; immunoprecipitation; inflammation; lipid oxidation; liver disease; liver fibrosis; macroautophagy; nerve degeneration; nonhuman; obesity; oxidative stress; protein synthesis; Review; upregulation; autophagy; gene expression regulation; homeostasis; liver; metabolism; physiology | English | 2022 | 2022-02 | 10.3390/cells11040620 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | X-ray computed tomography, electron microscopy, and energy-dispersive X-ray spectroscopy of severed Zelkova serrata roots (Japanese elm tree) | X-ray computed tomography (XCT), field emission scanning electron microscopy (FESEM), and energy-dispersive X-ray spectroscopy (EDS) were evaluated for imaging and element identification of woody plant roots. Lateral roots of Japanese zelkova (Zelkova serrata) were severed in spring and maintained in soil for six months. The lateral roots were observed using XCT without maceration and sectioning. The general wood characteristics were discernible to reveal the bark and xylem structures in contrast-inverted tomograms. Virtual sections showed a newly formed ring of woundwood encircling the severed lateral roots. FESEM exhibited secondary xylem structures in which tyloses, fungal hyphae, and aggregates were present. While silicon was dispersed in and around the fungal hyphae, calcium was localized as distinct aggregates using EDS. These results suggest that the combined use of XCT, FESEM, and EDS has merit into the morphological assessment of tree health care, providing virtual sections, high-resolution images, and element composition from an entire woodblock. | Park, Junhyung; Seo, Dahye; Kim, Ki Woo | Kyungpook Natl Univ, Dept Ecol & Environm Syst, Sangju 37224, South Korea; Kyungpook Natl Univ, Tree Diagnost Ctr, Sangju 37224, South Korea | Kim, Ki Woo/AAW-9645-2021 | 57202928407; 57218319875; 57201369889 | kiwoo@knu.ac.kr; | MICRON | MICRON | 0968-4328 | 1878-4291 | 156 | SCIE | MICROSCOPY | 2022 | 2.4 | 31.2 | 0.31 | 2025-06-25 | 2 | 4 | Calcium; Hyphae; Occlusion; Silicon; Xylem | XYLEM; CALCIUM; SILICON; SYSTEMS; VISUALIZATION; ACCUMULATION; OCCLUSIONS; ENDOPHYTES; PATHOGEN; LEAVES | Calcium; Hyphae; Occlusion; Silicon; Xylem | Japan; Microscopy, Electron, Scanning; Plant Roots; Spectrometry, X-Ray Emission; Tomography, X-Ray Computed; Ulmaceae; Ulmus; X-Rays; Aggregates; Calcium; Computerized tomography; Energy dispersive spectroscopy; Field emission microscopes; Forestry; Scanning electron microscopy; Electrons energy; Energy dispersive X ray spectroscopy; Field emission scanning electron microscopy; Fungal hyphae; Hypha; Lateral roots; Occlusion; Woody plants; X-ray computed tomography; Xylem; elm; Japan; plant root; scanning electron microscopy; spectroscopy; Ulmaceae; X ray; x-ray computed tomography; Silicon | English | 2022 | 2022-05 | 10.1016/j.micron.2022.103231 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Perturbation-based pH control systems for buffer and equivalence points | The dynamics of the pH process is well-described by the Wiener model, in which a nonlinear static function follows a linear dynamic subsystem. Gain scheduling applied to the process output, or equivalently to the controller gain, has to be used to keep the pH process at a given set point under the severe static nonlinearity of the titration curve. The present study investigates two control problems of keeping the pH process on the buffer and equivalence points. The proposed method uses extremum seeking control techniques to find the first and second derivatives with continuous process input perturbations. It finds and maintains process operating points where the second derivatives of pH with respect to the process input changes are zero, the local points of minimum and maximum slopes. The performances of the proposed method are verified with simulation and experiment. | Lim, Sanghun; Heo, Jea Pil; Ahn, Gwangnoh; Ryu, Kyung Hwan; Sung, Su Whan; Lee, Jietae | Kyungpook Natl Univ, Dept Chem Engn, 80 Daehak Ro, Daegu 41566, South Korea; Sunchon Natl Univ, Dept Chem Engn, 225 Jungang Ro, Sunchon 57922, South Korea | Lee, Si/ABH-1408-2020 | 57218849821; 57189221315; 57210798725; 55376077100; 7202731867; 7601455194 | suwhansung@knu.ac.kr;jtlee@knu.ac.kr; | COMPUTERS & CHEMICAL ENGINEERING | COMPUT CHEM ENG | 0098-1354 | 1873-4375 | 168 | SCIE | COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS;ENGINEERING, CHEMICAL | 2022 | 4.3 | 31.3 | 0 | 2025-06-25 | 0 | 0 | pH control; Buffer point; Equivalence point; Extremum seeking control; Continuous perturbation | EXTREMUM-SEEKING CONTROL; BIOHYDROGEN PRODUCTION; FEEDBACK; IDENTIFICATION; STABILITY; WATER; DARK | Buffer point; Continuous perturbation; Equivalence point; Extremum seeking control; pH control | Control theory; Buffer point; Continuous perturbation; Equivalence point; Extremum seeking control; PH control; pH control systems; pH process; Process inputs; Second derivatives; Wiener models; Functions | English | 2022 | 2022-12 | 10.1016/j.compchemeng.2022.108065 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Evaluation of recent changes in genetic variability in Thoroughbred horses based on microsatellite markers parentage panel in Korea | Objective: In this study, we aimed to investigate the recent changes such as allele frequencies and total probability of exclusion (PE) in Thoroughbred horses in Korea using short tandem repeat (STR) parentage panels between 2006 and 2016. Methods: The genotype was provided for 5,988 horse samples with 15 microsatellite markers (AHT4, AHT5, ASB2, ASB17, ASB23, CA425, HMS1, HMS2, HMS3, HMS6, HMS7, HTG4, HTG10, LEX3 and VHL20). Results: In our study, the observed number of alleles per locus ranged from 3 (HMS1) to 9 (ASB17) in 2006 and 4 (HMS1) to 9 (ASB2) in 2016, with a mean value of 6.28 and 6.40, respectively. Of the 15 markers, HMS2, HTG4, and CA425 loci had relatively low polymorphism information content (<0.5000) in the Thoroughbred population. Mean levels of genetic variation in 2006 and 2016 were observed heterozygosity (HO) = 0.708, and expected heterozygosity (HE) = 0.685, as well as and HO = 0.699 and HE = 0.682, respectively. The PE was calculated for each group based on the allele frequencies of 14 or 15 STRs. The 2006 survey analyzed that PE was 0.9998, but it increased to 0.9999 in 2016 after the HMS2 marker was added in 2011. The current STR panel is still a powerful tool for parentage verification that contributes to the maintenance of integrity in the Thoroughbred population. Conclusion: The current STR panel is still a powerful tool for parentage verification that contributes to the maintenance of integrity in the Thoroughbred horses. However, continuous monitoring genetic variability is necessary. | Park, Chul Sung; Lee, Sun Young; Cho, Gil Jae | Kyungpook Natl Univ, Coll Vet Med, Daegu 41566, South Korea; Kyungpook Natl Univ, Inst Equine Med, Daegu 41566, South Korea; Korea Racing Assoc, Racing Lab, Gwacheon 13822, South Korea | 57194528075; 12779346300; 7201438083 | chogj@knu.ac.kr; | ANIMAL BIOSCIENCE | ANIM BIOSCI | 2765-0189 | 2765-0235 | 35 | 4 | SCIE | AGRICULTURE, DAIRY & ANIMAL SCIENCE | 2022 | 2.2 | 31.5 | 0.41 | 2025-06-25 | 5 | 4 | Individual Identification; Microsatellite Marker; Parentage Verification; South Korea; Thoroughbred Horse | PIG BREEDS; VALIDATION; POPULATION | Individual Identification; Microsatellite Marker; Parentage Verification; South Korea; Thoroughbred Horse | English | 2022 | 2022-04 | 10.5713/ab.21.0272 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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