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WoS SCOPUS Document Type Document Title Abstract Authors Affiliation ResearcherID (WoS) AuthorsID (SCOPUS) Author Email(s) Journal Name JCR Abbreviation ISSN eISSN Volume Issue WoS Edition WoS Category JCR Year IF JCR (%) FWCI FWCI Update Date WoS Citation SCOPUS Citation Keywords (WoS) KeywordsPlus (WoS) Keywords (SCOPUS) KeywordsPlus (SCOPUS) Language Publication Stage Publication Year Publication Date DOI JCR Link DOI Link WOS Link SCOPUS Link
Article Comparison of three risk stratification models for non-clear cell renal cell carcinoma patients treated with temsirolimus as first-line therapy Background/Aims: For metastatic renal cell carcinoma (RCC), various prognostic scoring systems have been developed. However, owing to the low prevalence of non-clear cell RCC, the three most commonly used tools were mainly developed based on patients with clear cell histology. Accordingly, this study applied three prognostic models to Korean non-clear cell RCC patients treated with first-line temsirolimus. Methods: This study analyzed data for 74 patients with non-clear cell RCC who were treated with temsirolimus as the first-line therapy at eight medical centers between 2011 and 2016. The receiver-operating characteristic (ROC) curves for the different prognostic models were analyzed. Results: Twenty-seven (36.5%), 24 (32.4%), and 44 patients (59.5%) were assigned to the poor prognosis groups of the Memorial Sloan-Kettering Cancer Center (MSKCC), International Metastatic RCC Database Consortium (IMDC), and Advanced Renal Cell Carcinoma (ARCC) risk stratification models, respectively. All three prognostic models reliably discriminated the risk groups to predict progression-free survival and overall survival (p < 0.001.). The area under the ROC curve (AUC) for progression and survival was highest for the ARCC model (0.777; 0.734), followed by the IMDC (0.756; 0.724) and the MSKCC (0.742; 0.712) models. Furthermore, the sensitivity and specificity for predicting progression were highest with the ARCC model (sensitivity 63.6%, specificity 85.7%), followed by the MSKCC (sensitivity 58.2%, specificity 86.5%) and the IMDC models (sensitivity 56.4%, specificity 85.7%). Conclusions: All three prognostic models accurately predicted the survival of the non-clear cell RCC patients treated with temsirolimus as the first-line therapy. Furthermore, the ARCC risk model performed better than the other risk models in predicting survival. Lee, In Hee; Kang, Byung Woog; Kim, Jong Gwang; Bae, Woo Kyun; Ki, Myung Seo; Park, Inkeun; Jo, Jae-Cheol; Kim, Jin Young; Koh, Sung Ae; Lee, Kyung Hee; Cho, Yoon Young; Ryoo, Hun Mo; Kwak, Sang Gyu; Lee, Jung Lim; Lee, Sun Ah Kyungpook Natl Univ, Kyungpook Natl Univ Chilgok Hosp, Sch Med, Dept Oncol Hematol, Daegu, South Korea; Chonnam Natl Univ, Dept Internal Med, Med Sch, Gwangju, South Korea; Gachon Univ, Dept Internal Med, Div Med Oncol, Gil Med Ctr, 21 Namdong Daero 774beon Gil, Incheon 21565, South Korea; Ulsan Univ Hosp, Dept Hematol & Oncol, Ulsan, South Korea; Keimyung Univ, Dept Internal Med, Div Hematol Oncol, Dongsan Med Ctr, Daegu, South Korea; Yeungnam Univ, Dept Hematol Oncol, Coll Med, Daegu, South Korea; Daegu Catholic Univ, Dept Hematol Oncol, Med Ctr, Daegu, South Korea; Daegu Catholic Univ, Dept Med Stat, Med Ctr, Daegu, South Korea; Daegu Fatima Hosp, Dept Oncol Hematol, Daegu, South Korea; Daegu Catholic Univ, Dept Internal Med, Div Hematol Oncol, Sch Med, Daegu, South Korea Kim, Sung-Bae/JXL-8219-2024; Kim, Kyu-Sik/V-9262-2017; Jo, Jae-Cheol/CAE-9453-2022; Kim, Ji/AAO-7560-2021; Kwak, Sang Gyu/AAG-4341-2021 57191881516; 28567838500; 34771414000; 14028001300; 56478592900; 25947690900; 35818309200; 57196169650; 54383374000; 57196250869; 57203522631; 19738174500; 56645812600; 16203096000; 57192516061 bwkang@knu.ac.kr;bwkang@knu.ac.krInkeun; KOREAN JOURNAL OF INTERNAL MEDICINE KOREAN J INTERN MED 1226-3303 2005-6648 35 1 SCIE MEDICINE, GENERAL & INTERNAL 2020 2.884 35.6 0.07 2025-06-25 1 1 Non-clear cell renal cell carcinoma; Temsirolimus; Prognostic model; Survival PROGNOSTIC-FACTORS; TARGETED THERAPY; INTERFERON-ALPHA; SURVIVAL; CANCER; TUMORS; CLASSIFICATION; VALIDATION Non-clear cell renal cell carcinoma; Prognostic model; Survival; Temsirolimus Carcinoma, Renal Cell; Humans; Kidney Neoplasms; Prognosis; Retrospective Studies; Risk Assessment; Sirolimus; temsirolimus; rapamycin; temsirolimus; adult; Advanced Renal Cell Carcinoma score; aged; Article; cancer growth; cancer patient; cancer prognosis; comparative study; controlled study; female; human; International Metastatic RCC Database Consortium score; Korean (people); major clinical study; male; Memorial Sloan Kettering Cancer Center score; multiple cycle treatment; nephrectomy; neutrophilia; non clear cell renal cell carcinoma; overall survival; prognostic assessment; progression free survival; renal cell carcinoma; retrospective study; risk assessment; sensitivity and specificity; thrombocytosis; kidney tumor; prognosis; renal cell carcinoma English 2020 2020-01 10.3904/kjim.2018.064 바로가기 바로가기 바로가기 바로가기
Article Consensus statement on coronary intervention during the coronavirus disease 19 pandemic: from the Korean Society of Interventional Cardiology Coronavirus disease 2019 (COVID-19) is a highly contagious disease caused by the novel virus severe acute respiratory syndrome coronavirus 2. The first case developed in December, 2019 in Wuhan, China; several months later, COVID-19 has become pandemic, and there is no end in sight. This disaster is also causing serious health problems in the area of cardiovascular intervention. In response, the Korean Society of Interventional Cardiology formed a COVID-19 task force to develop practice guidelines. This special article introduces clinical practice guidelines to prevent secondary transmission of COVID-19 within facilities; the guidelines were developed to protect patients and healthcare workers from this highly contagious virus. We hope these guidelines help healthcare workers and cardiovascular disease patients around the world cope with the COVID-19 pandemic. Lee, Kwan Yong; Lee, Bong-Ki; Kim, Won-Jang; Kang, Se Hun; Park, Taek Kyu; Kim, Song-Yi; Suh, Jung-Won; Yoon, Chang-Hwan; Yang, Dong Heon; Ryu, Sung Kee; Kim, Sang-Hyun; Lee, Sung Yun; Chae, In-Ho Catholic Univ Korea, Incheon St Marys Hosp, Coll Med, Dept Cardiol, Incheon, South Korea; Kangwon Natl Univ Hosp, Dept Internal Med, Div Cardiol, Chunchon, South Korea; CHA Univ, CHA Bundang Med Ctr, Dept Cardiol, Seongnam, South Korea; Sungkyunkwan Univ, Samsung Med Ctr, Sch Med, Heart Vasc & Stroke Inst,Div Cardiol,Dept Med, Seoul, South Korea; Jeju Natl Univ Hosp, Dept Internal Med, Div Cardiol, Jeju, South Korea; Seoul Natl Univ, Bundang Hosp, Cardiovasc Ctr, 82 Gumi Ro 173beon Gil, Seongnam 13620, South Korea; Kyungpook Natl Univ Hosp, Dept Internal Med, Div Cardiol, Daegu, South Korea; Nowon Eulji Med Ctr, Dept Internal Med, Div Cardiol, Seoul, South Korea; Seoul Natl Univ, Boramae Med Ctr, Dept Internal Med, Div Cardiol,Seoul Metropolitan Govt, Seoul, South Korea; Inje Univ, Ilsan Paik Hosp, Cardiac & Vasc Ctr, Goyang, South Korea Yoon, Changhwan/MXM-0567-2025; Kim, Sang-Hyun/J-5402-2012; Kim, Song-Yi/JAC-5358-2023; Chae, In-Ho/J-5682-2012; Kang, Se Hun/HDO-2406-2022 57203317356; 7405442104; 37070117400; 25421794000; 55750570800; 35740671300; 35273808100; 7202882965; 35277423400; 15736269700; 49663680000; 25623542700; 35274374100 ihchae@snu.ac.kr; KOREAN JOURNAL OF INTERNAL MEDICINE KOREAN J INTERN MED 1226-3303 2005-6648 35 4 SCIE MEDICINE, GENERAL & INTERNAL 2020 2.884 35.6 0.13 2025-06-25 2 2 COVID-19; Cardiovascular diseases; Coronary angiography; Percutaneous coronary intervention; Practice guideline PNEUMONIA; WUHAN Cardiovascular diseases; Coronary angiography; COVID-19; Percutaneous coronary intervention; Practice guideline Air Conditioning; Betacoronavirus; Clinical Laboratory Techniques; Coronavirus Infections; Disinfection; Humans; Myocardial Ischemia; Pandemics; Patient Transfer; Percutaneous Coronary Intervention; Personal Protective Equipment; Pneumonia, Viral; Triage; air conditioning; Article; cardiac patient; cardiogenic shock; cardiovascular disease; clinical protocol; consensus; coping behavior; coronavirus disease 2019; diagnostic test; disinfection; emergency health service; health care facility; health care personnel; heart arrest; human; interventional cardiovascular procedure; intubation; medical society; non ST segment elevation myocardial infarction; nonhuman; pandemic; patient safety; patient selection; patient transport; percutaneous coronary intervention; practice guideline; Severe acute respiratory syndrome coronavirus 2; South Korea; ST segment elevation myocardial infarction; virus transmission; Betacoronavirus; Coronavirus infection; heart muscle ischemia; laboratory technique; pandemic; protective equipment; virus pneumonia English 2020 2020-07 10.3904/kjim.2020.290 바로가기 바로가기 바로가기 바로가기
Article J-curve relationship between corrected QT interval and mortality in acute heart failure patients Background/Aims: This study investigated the prognostic power of corrected QT (QTc) interval in patients with acute heart failure (AHF) according to sex. Methods: We analyzed multicenter Korean Acute Heart Failure registry with patients with AHF admitted from 2011 to 2014. Among them, we analyzed 4,990 patients who were followed up to 5 years. Regarding QTc interval based on 12 lead electrocardiogram, patients were classified into quartiles according to sex. Results: During follow-up with median 43.7 months, 2 , 2 43 (44.9%) patients died. The relationship between corrected QT interval and all-cause mortality followed a J-curve relationship. In Kaplan-Meier analysis, both sex had lowest mortality in the second QTc quartile. There were significant prognostic differences between the second and the fourth quartiles in male (log-rank p = 0.002), but not in female (log-rank p = 0.338). After adjusting covariates, the third (hazard ratio [HR], 1.185; 95% confidence interval [CI], 1.001 to 1.404; p = 0.049) and the fourth (HR, 1.404; 95% CI, 1.091 to 1.535; p = 0.003) quartiles demonstrated increased risk of mortality compared to the second quartile in male. In female, however, there was no significant difference across quartiles. QTc interval was associated with 5-year all-cause mortality in J-shape with nadir of 440 to 450 ms in male and 470 to 480 ms in female. Conclusions: QTc interval was an independent predictor of overall death in male, but its significance decreased in female. The relationship between QTc interval and all-cause mortality was J-shaped in both sex. Park, Chan Soon; Cho, Hyun-Jai; Choi, Eue-Keun; Lee, Sang Eun; Kim, Min-Seok; Kim, Jae-Joong; Choi, Jin-Oh; Jeon, Eun-Seok; Hwang, Kyung-Kuk; Chae, Shung Chull; Baek, Sang Hong; Kang, Seok-Min; Yoo, Byungsu; Choi, Dong-Ju; Ahn, Youngkeun; Kim, Kye-Hoon; Cho, Myeong-Chan; Oh, Byung-Hee; Lee, Hae-Young Korea Adv Inst Sci & Technol, Grad Sch Med Sci & Engn, Daejeon, South Korea; Seoul Natl Univ Hosp, Dept Internal Med, Seoul, South Korea; Univ Ulsan, Asan Med Ctr, Dept Internal Med, Div Cardiol,Coll Med, Seoul, South Korea; Sungkyunkwan Univ, Dept Internal Med, Coll Med, Seoul, South Korea; Chungbuk Natl Univ, Dept Internal Med, Coll Med, Cheongju, South Korea; Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu, South Korea; Catholic Univ Korea, Coll Med, Dept Internal Med, Seoul, South Korea; Yonsei Univ, Dept Internal Med, Coll Med, Seoul, South Korea; Yonsei Univ, Dept Internal Med, Wonju Coll Med, Wonju, South Korea; Seoul Natl Univ, Cardiovasc Ctr, Div Cardiol, Bundang Hosp, Seongnam, South Korea; Chonnam Natl Univ, Heart Res Ctr, Gwangju, South Korea; Mediplex Sejong Hosp, Dept Internal Med, Incheon, South Korea ; Choi, Eue-Keun/J-5968-2014; LEE, JI/L-6920-2013; Choi, Dong-Ju/J-5686-2012; Kim, Soo-Yeon/ADR-9663-2022; Jeong, Gi/AAB-2830-2021; Choi, Joon/D-6140-2017; Oh, Byung-Hee/G-9875-2011 57198830480; 35285421400; 35558194200; 57207065107; 57212315719; 36065764100; 15848011800; 7004279641; 7402426370; 7101962036; 7201371594; 7405685375; 7102851884; 35274349200; 56937721300; 57203567544; 7401727518; 57216293873; 56151235500 hylee612@snu.ac.kr; KOREAN JOURNAL OF INTERNAL MEDICINE KOREAN J INTERN MED 1226-3303 2005-6648 35 6 SCIE MEDICINE, GENERAL & INTERNAL 2020 2.884 35.6 0.33 2025-06-25 7 7 Heart failure; QTc interval; Sex; Mortality; Prognosis LONG-TERM MORTALITY; CARDIOVASCULAR MORTALITY; SEX-DIFFERENCES; ALL-CAUSE; RISK; DISPERSION; PROLONGATION; POPULATION; ASSOCIATION; PREDICTION Heart failure; Mortality; Prognosis; QTc interval; Sex Aged; Alcohol Drinking; Electrocardiography; Female; Heart Failure; Heart Rate; Humans; Male; Middle Aged; Prognosis; Proportional Hazards Models; Risk Factors; acute heart failure; aged; all cause mortality; Article; cardiovascular mortality; disease classification; electrocardiography; female; follow up; hospital admission; human; Korea; major clinical study; male; mortality risk; outcome assessment; prognosis; QT interval; sex difference; clinical trial; drinking behavior; heart failure; heart rate; middle aged; multicenter study; proportional hazards model; risk factor English 2020 2020-11 10.3904/kjim.2019.030 바로가기 바로가기 바로가기 바로가기
Article Low parathyroid hormone level predicts infection-related mortality in incident dialysis patients: a prospective cohort study Background/Aims: Parathyroid hormone (PTH) is an important factor influencing immunologic dysfunction, but the effect of PTH level on infection-related outcomes remains unclear in incident dialysis. Methods: We evaluated a multicenter prospective cohort study of 1,771 incident dialysis patients (1,260 hemodialysis and 511 peritoneal dialysis) in Korea. Patients were divided into three groups based on serum intact PTH (iPTH) level. The primary outcomes were all-cause and infection-related mortality and multivariate Cox regression analysis was performed to evaluate the role of iPTH in all-cause and infection-related mortality. Results: During the follow-up period of 27.3 months, 175 patients (9.9%) died, and infection-related death represented 20% of all-cause mortality. Both all-cause mortality and infection-related mortality rates (p < 0.001 and p = 0.003, by log-rank) were markedly higher in patients with serum iPTH < 1.50 pg/mL than in the other groups. Multivariate Cox regression analysis revealed that patients with serum iPTH < 150 pg/mL remained at higher risk for infection-related mortality than patients in the target range of 150 <= iPTH < 300 pg/mL, after adjusting for confounding variables (hazard ratio [HR], 2.52; 95% confidence interval, 1.06 to 5.99; p = 0.04). The HR of infection-related mortality in patients with serum iPTH < 150 pg/mL was significantly higher in patients with low serum phosphorus, low Ca x P product, low serum alkaline phosphatase and those older than 65 years. Conclusions: Low serum iPTH level is an independent predictor of infection-related mortality in incident dialysis patients. Hong, Yu Ah; Kim, Jeong Ho; Kim, Yong Kyun; Chang, Yoon Kyung; Park, Cheol Whee; Kim, Suk Young; Kim, Yon Su; Kang, Shin-Wook; Kim, Nam-Ho; Kim, Yong-Lim; Yang, Chul Woo Catholic Univ Korea, Coll Med, Dept Internal Med, Seoul, South Korea; Seoul Natl Univ, Dept Internal Med, Coll Med, Seoul, South Korea; Clin Res Ctr End Stage Renal Dis, Daegu, South Korea; Yonsei Univ, Dept Internal Med, Coll Med, Seoul, South Korea; Chonnam Natl Univ, Dept Internal Med, Med Sch, Gwangju, South Korea; Kyungpook Natl Univ Hosp, Dept Internal Med, Daegu, South Korea Hong, Yu/AAB-7055-2020; Kim, Yong-Lim/AGK-3172-2022 55125210000; 56438214000; 57218459728; 55501371200; 34880445500; 56666974200; 7410205767; 34768359700; 56605215700; 55633533600; 7407743404 yangch@catholic.ac.kr; KOREAN JOURNAL OF INTERNAL MEDICINE KOREAN J INTERN MED 1226-3303 2005-6648 35 1 SCIE MEDICINE, GENERAL & INTERNAL 2020 2.884 35.6 0.99 2025-06-25 22 20 Parathyroid hormone; Infection; Mortality; Dialysis ADYNAMIC BONE-DISEASE; HEMODIALYSIS-PATIENTS; MINERAL METABOLISM; ALKALINE-PHOSPHATASE; SURVIVAL; CALCIUM; RISK; PREDICTABILITY; ASSOCIATION; MORBIDITY Dialysis; Infection; Mortality; Parathyroid hormone Calcium; Humans; Parathyroid Hormone; Peritoneal Dialysis; Prospective Studies; Renal Dialysis; Republic of Korea; alkaline phosphatase; parathyroid hormone; phosphate; calcium; parathyroid hormone; adult; alkaline phosphatase blood level; all cause mortality; Article; blood sampling; Charlson Comorbidity Index; cohort analysis; controlled study; female; follow up; hemodialysis; hemodialysis patient; human; infection; major clinical study; male; mortality rate; multicenter study; multivariate analysis; observational study; outcome assessment; parathyroid hormone blood level; peritoneal dialysis; phosphate blood level; prospective study; regression analysis; South Korea; adverse event; clinical trial; hemodialysis; peritoneal dialysis English 2020 2020-01 10.3904/kjim.2018.264 바로가기 바로가기 바로가기 바로가기
Article Pre-hospital delay and emergency medical services in acute myocardial infarction Background/Aims: Minimising total ischemic time (TIT) is important for improving clinical outcomes in patients with ST-segment elevation myocardial infarction who have undergone percutaneous coronary intervention (PCI). TIT has not shown a significant improvement due to persistent pre-hospital delay. This study aimed to investigate the risk factors associated with pre-hospital delay. Methods: Individuals enrolled in the Korea Acute Myocardial Infarction Registry-National Institutes of Health between 2011 and 2015 were included in this study. The study population was analyzed according to the symptomto-door time (STDT; within 60 or > 60 minutes), and according to the type of hospital visit (emergency medical services [EMS], non-PCI center, or PCI center). Results: A total of 4,874 patients were included in the analysis, of whom 28.4% arrived at the hospital within 60 minutes of symptom-onset. Old age (> 65 years), female gender, and renewed ischemia were independent predictors of delayed STDT. Utilising EMS was the only factor shown to reduce STDT within 60 minutes, even when cardiogenic shock was evident. The overall frequency of EMS utilisation was low (21.7%). Female gender was associated with not utilising EMS, whereas cardiogenic shock, previous myocardial infarction, familial history of ischemic heart disease, and off-hour visits were associated with utilising EMS. Conclusions: Factors associated with delayed STDT and not utilising EMS could be targets for preventive intervention to improve STDT and TIT. Lee, Seung Hun; Kim, Hyun Kuk; Jeong, Myung Ho; Lee, Joo Myung; Gwon, Hyeon-Cheol; Chae, Shung Chull; Seong, In-Whan; Park, Jong-Seon; Chae, Jei Keon; Hur, Seung-Ho; Cha, Kwang Soo; Kim, Hyo-Soo; Seung, Ki-Bae; Rha, Seung-Woon; Ahn, Tae Hoon; Kim, Chong-Jin; Hwang, Jin-Yong; Choi, Dong-Ju; Yoon, Junghan; Joo, Seung-Jae; Hwang, Kyung-Kuk; Kim, Doo-Il; Oh, Seok Kyu Chonnam Natl Univ Hosp, Dept Cardiol, 42 Jebong Ro, Gwangju 61469, South Korea; Sungkyunkwan Univ, Samsung Med Ctr, Heart Vasc & Stroke Inst, Sch Med, Seoul, South Korea; Chosun Univ Hosp, Dept Cardiol, Gwangju, South Korea; Kyungpook Natl Univ Hosp, Dept Internal Med, Daegu, South Korea; Chungnam Natl Univ Hosp, Dept Internal Med, Daejeon, South Korea; Yeungnam Univ, Div Cardiol, Med Ctr, Daegu, South Korea; Chonbuk Natl Univ, Dept Internal Med, Div Cardiol, Med Sch, Jeonju, South Korea; Keimyung Univ, Dept Cardiovasc Med, Dongsan Med Ctr, Daegu, South Korea; Pusan Natl Univ Hosp, Dept Cardiol, Busan, South Korea; Seoul Natl Univ Hosp, Cardiovasc Ctr, Dept Internal Med, Seoul, South Korea; Catholic Univ Korea, Coll Med, Dept Internal Med, Div Cardiol, Seoul, South Korea; Korea Univ, Cardiovasc Ctr, Guro Hosp, Seoul, South Korea; Gachon Univ, Dept Cardiol, Gil Med Ctr, Incheon, South Korea; Kyung Hee Univ Hosp Gangdong, Dept Cardiol, Seoul, South Korea; Gyeongsang Natl Univ Hosp, Dept Internal Med, Jinju, South Korea; Seoul Natl Univ, Cardiovasc Ctr, Bundang Hosp, Seongnam, South Korea; Yonsei Univ, Wonju Severance Christian Hosp, Dept Internal Med, Div Cardiol,Wonju Coll Med, Wonju, South Korea; Jeju Natl Univ, Dept Internal Med, Sch Med, Jeju, South Korea; Chungbuk Natl Univ, Dept Internal Med, Coll Med, Cheongju, South Korea; Inje Univ, Dept Internal Med, Haeundae Paik Hosp, Busan, South Korea; Wonkwang Univ, Dept Internal Med, Div Cardiol, Sch Med, Iksan, South Korea Kim, Jin Sug/AAY-6890-2021; Choi, Dong-Ju/J-5686-2012; Lee, Seung/AAW-6430-2021; 안, 태훈/GON-9067-2022; Lee, Jae/J-5597-2012; Kim, Hyo/J-2753-2012; Rha, Seung-Woon/AGE-5810-2022; Jeong, Young-Hoon/F-3476-2015 57203597270; 57206210646; 56485157500; 54894745500; 6603262426; 7101962036; 35254371300; 15763054600; 26029709000; 34570274500; 7102837700; 33567809200; 7003964208; 8569030400; 57202554645; 35229511500; 55892914700; 35274349200; 35760728900; 9236504200; 7402426370; 8635545900; 24734336000 myungho@chollian.net; KOREAN JOURNAL OF INTERNAL MEDICINE KOREAN J INTERN MED 1226-3303 2005-6648 35 1 SCIE MEDICINE, GENERAL & INTERNAL 2020 2.884 35.6 1.05 2025-06-25 23 24 Time factors; Emergency medical services; Myocardial infarction; Cardiogenic shock; Prognosis ST-SEGMENT-ELEVATION; PERCUTANEOUS CORONARY INTERVENTION; PRIMARY ANGIOPLASTY; SYMPTOM ONSET; TIME-DELAY; PREDICTORS; IMPACT; GUIDELINES; MANAGEMENT; MORTALITY Cardiogenic shock; Emergency medical services; Myocardial infarction; Prognosis; Time factors Aged; Emergency Medical Services; Female; Hospitals; Humans; Myocardial Infarction; Percutaneous Coronary Intervention; Republic of Korea; acetylsalicylic acid; angiotensin receptor antagonist; beta adrenergic receptor blocking agent; clopidogrel; dipeptidyl carboxypeptidase inhibitor; fibrinogen receptor antagonist; hydroxymethylglutaryl coenzyme A reductase inhibitor; prasugrel; ticagrelor; acute heart infarction; adult; aged; Article; cardiogenic shock; controlled study; disease marker; disease registry; emergency health service; family history; female; gender; health care utilization; heart muscle ischemia; human; ischemic heart disease; major clinical study; male; population research; prediction; risk assessment; risk factor; South Korea; therapy delay; time to treatment; adverse event; heart infarction; hospital; percutaneous coronary intervention English 2020 2020-01 10.3904/kjim.2019.123 바로가기 바로가기 바로가기 바로가기
Article The clinical and economic burden of community-onset complicated skin and skin structure infections in Korea Background/Aims: To investigate epidemiologic characteristics, clinical and economic burdens, and factors associated with mortality in complicated skin and skin structure infection (cSSSI) patients in Korea. Methods: A retrospective, observational, nationwide study was conducted between April to July 2012 at 14 tertiary-hospitals in Korea. Eligible patients were hospitalized adults with community acquired cSSSI, who underwent surgical intervention and completed treatment between November 2009 and October 2011. Data on demography, clinical characteristics, outcomes and medical resource utilization were collected through medical record review. Direct medical costs were calculated by multiplying quantities of resources utilized by each unit price in Korea. Results: Of 473 patients enrolled, 449 patients (except 24 patients with no record on surgical intervention) were eligible for analysis. Microbiological testing was performed on 66.1% of patients and 8.2% had multiple pathogens. Among culture confirmed pathogens (n = 297 patients, 34o episodes), 76.2% were gram-positive (Staphylococcus aureus; 41.2%) and 23.8% were gram-negative. The median duration of hospital stay was 16 days. Among treated patients, 3.3% experienced recurrence and 4.2% died in-hospital. The mean direct medical costs amounted to $4,195/person, with the greatest expenses for hospitalization and antibiotics. The in-hospital mortality and total medical costs were higher in combined antibiotics therapy than monotherapy (p = 3, standardized early warning scoring >= 4, sub-fascia infections and combined initial therapy, were all found to be associated with higher mortality. Conclusions: Korean patients with community-onset cSSSI suffer from considerable clinical and economic burden. Efforts should be made to reduce this burden through appropriate initial treatment. Cho, Yong Kyun; Woo, Heung Jeong; Kim, Shin Woo; Bae, In-Gyu; Song, Young Goo; Cheong, Hee Jin; Lee, Hyuck; Han, Sang Hoon; Choi, Hee Jung; Moon, Chisook; Ryu, Seong Yeol; Hur, Jian; Lee, Ja Cob; Jo, Yu Mi; Kim, Young Joo Gachon Univ, Dept Internal Med, Coll Med, Incheon, South Korea; Hallym Univ, Dept Internal Med, Coll Med, Chunchon, South Korea; Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu, South Korea; Gyeongsang Natl Univ, Dept Internal Med, Coll Med, Jinju, South Korea; Yonsei Univ, Dept Internal Med, Coll Med, Seoul, South Korea; Korea Univ, Dept Internal Med, Coll Med, Seoul, South Korea; Dong A Univ, Dept Internal Med, Coll Med, Busan, South Korea; Ewha Womans Univ, Dept Internal Med, Coll Med, Seoul, South Korea; Inje Univ, Dept Internal Med, Coll Med, Busan, South Korea; Keimyung Univ, Dept Internal Med, Coll Med, Daegu, South Korea; Yeungnam Univ, Dept Internal Med, Coll Med, Daegu, South Korea; Pfizer Pharmaceut Korea Ltd, Seoul, South Korea Kim, Hyunho/GQH-5608-2022; Song, Young Goo/AGV-5104-2022; Kim, Woo/D-2733-2015 57222306801; 57201778265; 8710731500; 7004882611; 25951692300; 7102495865; 35076225200; 24168229300; 57217262202; 22980995800; 9733513600; 19934047300; 13406664300; 18634063300; 57207443255 karmacho@gmail.com; KOREAN JOURNAL OF INTERNAL MEDICINE KOREAN J INTERN MED 1226-3303 2005-6648 35 6 SCIE MEDICINE, GENERAL & INTERNAL 2020 2.884 35.6 0.07 2025-06-25 2 2 Complicated skin and skin structure infection; Economic; Clinical burden; Initial antibiotics SOFT-TISSUE INFECTIONS; MANAGEMENT; PATTERNS Clinical burden; Complicated skin and skin structure infection; Economic; Initial antibiotics Adult; Anti-Bacterial Agents; Cost of Illness; Female; Hospitalization; Humans; Length of Stay; Male; Republic of Korea; Retrospective Studies; Skin Diseases; antibiotic agent; antiinfective agent; adult; aged; Article; Charlson Comorbidity Index; clinical feature; community acquired infection; complicated skin and skin structure infection; controlled study; demography; disease burden; economics; female; Gram negative bacterium; Gram positive bacterium; health care utilization; hospital cost; hospital patient; hospitalization; human; length of stay; major clinical study; male; medical record review; microbiological examination; monotherapy; mortality; nonhuman; observational study; recurrent disease; retrospective study; skin infection; skin structure; skin surgery; South Korea; Staphylococcus aureus; tertiary care center; cost of illness; economics; epidemiology; skin disease English 2020 2020-11 10.3904/kjim.2018.374 바로가기 바로가기 바로가기 바로가기
Article The effect of susceptibility variants, identified in never-smoking female lung cancer cases, on male smokers Background/Aims: Genome wide and candidate gene association studies have identified polymorphisms associated with the risk of lung cancer in never-smokers. This study was conducted to evaluate the association between 11 polymorphisms identified in female never smokers and the lung cancer risk in male smokers. Methods: This study included 714 lung cancer patients and 626 healthy controls. The polymorphisms were genotyped using SEQUENOM MassARRAY iPLEX assay or Taq-Man assay. Results: Two polymorphisms were associated with the risk of lung cancer in male smokers, as in female never smokers. Male smokers carrying the rs4975616 variant allele had a significantly decreased risk of lung cancer (in a codominant model: odds ratio, 0.77; 95% confidence interval, 0.61 to 0.96; p = 0.02). The rs9387478 polymorphism also reduced lung cancer risk in male smokers (in a codominant model: odds ratio, 0.85; 95% confidence interval, 0.73 to 0.997; p = 0.046). In a stratified analysis, the association between these polymorphisms and the risk of lung cancer was predominant in lighter smokers and for cases of adenocarcinoma. Conclusions: These results suggest that a subset of polymorphisms known to be associated with the risk of lung cancer in female never smokers is also associated with the risk of lung cancer in male smokers. Yoo, Seung Soo; Kang, Hyo-Gyoung; Choi, Jin Eun; Hong, Mi Jeong; Do, Sook Kyung; Lee, Jang Hyuck; Lee, Won Kee; Lee, Shin Yup; Lee, Jaehee; Cha, Seung Ick; Kim, Chang Ho; Lee, Eung Bae; Park, Jae Yong Kyungpook Natl Univ Hosp, Dept Internal Med, Daegu, South Korea; Kyungpook Natl Univ, Lung Canc Ctr, Chilgok Hosp, 807 Hoguk Ro, Daegu 41404, South Korea; Kyungpook Natl Univ, Dept Biochem & Cell Biol, Sch Med, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Cell & Matrix Res Inst, Daegu, South Korea; Kyungpook Natl Univ, Dept Biomed Sci, BK21 Plus KNU Biomed Convergence Program, Daegu, South Korea; Kyungpook Natl Univ, Med Res Collaborat Ctr, Biostat, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Thorac Surg, Daegu, South Korea Lee, Yoojin/AAB-9799-2022; Lee, Jaehee/S-1697-2018 56479781600; 8573181300; 37107028100; 55613917100; 56333658000; 57161223200; 22953484700; 49863712700; 13805476000; 35227126400; 7409873555; 55664096100; 58360293800 jaeyong@knu.ac.kr; KOREAN JOURNAL OF INTERNAL MEDICINE KOREAN J INTERN MED 1226-3303 2005-6648 35 4 SCIE MEDICINE, GENERAL & INTERNAL 2020 2.884 35.6 0.13 2025-06-25 2 3 Lung neoplasms; Smokers; Non-smokers; Risk; Polymorphism GENOME-WIDE ASSOCIATION; RISK; POLYMORPHISM; LOCUS; GENE Lung neoplasms; Non-smokers; Polymorphism; Risk; Smokers Case-Control Studies; Female; Genetic Predisposition to Disease; Genotype; Humans; Lung Neoplasms; Male; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Risk Factors; Smokers; Smoking; telomerase reverse transcriptase; adult; allele; Article; cancer patient; cancer risk; cancer staging; CLPTM1L gene; codominance; controlled study; DCBLD1 gene; disease association; DNA polymorphism; female; gender; gene; genetic association; genetic susceptibility; genotype; heterozygote; human; human tissue; lung adenocarcinoma; lung cancer; major clinical study; male; never smoker; risk reduction; ROS1 gene; smoking; South Korea; TERT gene; adverse event; case control study; genetic polymorphism; genetic predisposition; genetics; lung tumor; risk factor; single nucleotide polymorphism English 2020 2020-07 10.3904/kjim.2018.417 바로가기 바로가기 바로가기 바로가기
Article What should we prepare for the next coronavirus disease 2019 outbreak? A survey on the opinions of infectious diseases specialists in South Korea Background/Aims: This study aimed to collect information on the opinions of Korean infectious disease (ID) experts on coronavirus disease 2019 (COVID-19) and related issues in preparation for a future outbreak. Methods: A survey was conducted over the course of 5 days (from April 21 to 25, 2020), targeting all adult ID specialists currently in the medical field in South Korea (n = 265). An online-based survey was forwarded via text message and e-mail. Only one response was accepted from each participant. Results: Of these 265 ID specialists gotten to, 132 (49.8%) responded. The highest proportion of the respondents envisaged the current COVID-19 outbreak to end after December 2020 (47.7% for the domestic Korean outbreak and 70.5% for the global pandemic); moreover, 60.7% of them stated that a second nationwide wave is likely to occur between September and December zozo in South Korea. N95 respirators were considered to be the most important item in hospitals in preparation for a second wave. The most important policy to be implemented at the national level was securing national hospitals designated for the treatment of ID (67.4%). Conclusions: ID experts in South Korea believe that the COVID-19 pandemic may not be easily controlled and that a second nationwide wave is likely to occur in South Korea. Our results indicate that Korean ID specialists believe that a high level of preparation is needed in various aspects, including the procurement of personal protective equipment, to respond efficiently to a second outbreak. Kim, Bongyoung; Park, Se Yoon; Jung, Dong Sik; Jung, Sook In; Oh, Won Sup; Kim, Shin-Woo; Peck, Kyong Ran; Chang, Hyun-Ha Hanyang Univ, Coll Med, Dept Internal Med, Seoul, South Korea; Soonchunhyang Univ, Seoul Hosp, Dept Internal Med, Div Infect Dis, Seoul, South Korea; Dong A Univ, Coll Med, Dept Internal Med, Div Infect Dis, Busan, South Korea; Chonnam Natl Univ, Med Sch, Dept Infect Dis, Gwangju, South Korea; Kangwon Natl Univ Hosp, Dept Internal Med, Div Infect Dis, Chunchon, South Korea; Kyungpook Natl Univ, Sch Med, Dept Internal Med, Div Infect Dis, 130 Dongdeok Ro, Daegu 41944, South Korea; Sungkyunkwan Univ, Samsung Med Ctr, Sch Med, Div Infect Dis, Seoul, South Korea Peck, Kyong Ran/AGV-5205-2022; JUNG, SOOK IN/AGO-2862-2022; Kim, Woo/AAG-1822-2019; Jung, Dong Sik/HOH-5826-2023; Kim, Wonhee/AAA-1074-2021 55622077200; 55259986400; 14023089600; 7403676835; 24778642500; 8710731500; 55664295200; 7407521688 changhha@knu.ac.kr; KOREAN JOURNAL OF INTERNAL MEDICINE KOREAN J INTERN MED 1226-3303 2005-6648 35 6 SCIE MEDICINE, GENERAL & INTERNAL 2020 2.884 35.6 0.2 2025-06-25 4 4 COVID-19; Communicable diseases; Korea Communicable diseases; COVID-19; Korea adult; Article; coronavirus disease 2019; e-mail; epidemic; female; health care policy; human; infection control; infection prevention; major clinical study; male; South Korea; text messaging; treatment indication English 2020 2020-11 10.3904/kjim.2020.222 바로가기 바로가기 바로가기 바로가기
Article MRI Assessment of Complete Response to Preoperative Chemoradiation Therapy for Rectal Cancer: 2020 Guide for Practice from the Korean Society of Abdominal Radiology Objective: To provide an evidence-based guide for the MRI interpretation of complete tumor response after neoadjuvant chemoradiation therapy (CRT) for rectal cancer using visual assessment on T2-weighted imaging (T2) and diffusion-weighted imaging (DWI). Materials and Methods: PubMed MEDLINE, EMBASE, and Cochrane Library were searched on November 28, 2019 to identify articles on the following issues: 1) sensitivity and specificity of T2 or DWI for diagnosing pathologic complete response (pCR) and the criteria for MRI diagnosis; 2) MRI alone vs. MRI combined with other test(s) in sensitivity and specificity for pCR; and 3) tests to select patients for the watch-and-wait management. Eligible articles were selected according to meticulous criteria and were synthesized. Results: Of 1615 article candidates, 55 eligible articles (for all three issues combined) were identified. Combined T2 and DWI performed better than T2 alone, with a meta-analytic summary sensitivity of 0.62 (95% confidence interval [CI], 0.43-0.77; I-2 = 80.60) and summary specificity of 0.89 (95% CI, 0.80-0.94; I-2 = 92.61) for diagnosing pCR. The criteria for the complete response on T2 in most studies had the commonality of remarkable tumor decrease to the absence of mass-like or nodular intermediate signal, although somewhat varied, as follows: (near) normalization of the wall; regular, thin, hypointense scar in the luminal side with (near) normal-appearance or homogeneous intermediate signal in the underlying wall; and hypointense thickening of the wall. The criteria on DWI were the absence of a hyperintense signal at high b-value (>= 800 sec/mm(2)) in most studies. The specific algorithm to combine T2 and DWI was obscure in half of the studies. MRI combined with endoscopy was the most utilized means to select patients for the watch-and-wait management despite a lack of strong evidence to guide and support a multi-test approach. Conclusion: This systematic review and meta-analysis provide an evidence-based practical guide for MRI assessment of complete tumor response after CRT for rectal cancer. Park, Seong Ho; Cho, Seung Hyun; Choi, Sang Hyun; Jang, Jong Keon; Kim, Min Ju; Kim, Seung Ho; Lim, Joon Seok; Moon, Sung Kyoung; Park, Ji Hoon; Seo, Nieun Univ Ulsan, Asan Med Ctr, Coll Med, Dept Radiol, 88 Olymp Ro 43 Gil, Seoul 05505, South Korea; Univ Ulsan, Asan Med Ctr, Coll Med, Res Inst Radiol, 88 Olymp Ro 43 Gil, Seoul 05505, South Korea; Kyungpook Natl Univ, Med Ctr, Sch Med, Dept Radiol, Daegu, South Korea; Ewha Womans Univ, Dept Radiol, Seoul Hosp, Seoul, South Korea; Inje Univ, Haeundae Paik Hosp, Dept Radiol, Coll Med, Busan, South Korea; Yonsei Univ, Severance Hosp, Dept Radiol, Coll Med, Seoul, South Korea; Kyung Hee Univ Hosp, Dept Radiol, Seoul, South Korea; Seoul Natl Univ, Bundang Hosp, Coll Med, Dept Radiol, Seongnam, South Korea Park, Seong Ho/E-2271-2014; Park, Ju Ok/GWQ-9476-2022; Park, Seong/J-5488-2012; Kim, Jwa/AAH-9915-2021; Lim, Joon Seok/R-7753-2019; Kim, Hyung/J-5451-2012; Choi, Sang Hyun/MXL-4605-2025 57049729900; 55686242700; 57207282569; 49661843500; 57222306871; 57201923781; 7403453992; 35798730300; 57022562700; 54387409200 parksh.radiology@gmail.com; KOREAN JOURNAL OF RADIOLOGY KOREAN J RADIOL 1229-6929 2005-8330 21 7 SCIE RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING 2020 3.5 35.7 2.52 2025-06-25 43 40 Rectal cancer; Adenocarcinoma; Chemoradiotherapy; Chemoradiation; Response; Remission; Regression; CR; Magnetic resonance imaging; Watch and wait; Wait and see; Organ preservation; Surveillance; Evidence; Guideline; Recommendation CLINICAL COMPLETE RESPONSE; WAIT-AND-SEE; EXTENDED NEOADJUVANT CHEMORADIATION; DIAGNOSTIC-TEST ACCURACY; TUMOR-REGRESSION GRADE; DIFFUSION-WEIGHTED MRI; NONOPERATIVE MANAGEMENT; EUROPEAN-SOCIETY; RADICAL SURGERY; FOLLOW-UP Adenocarcinoma; Chemoradiation; Chemoradiotherapy; CR; Evidence; Guideline; Magnetic resonance imaging; Organ preservation; Recommendation; Rectal cancer; Regression; Remission; Response; Surveillance; Wait and see; Watch and wait Algorithms; Chemoradiotherapy; Humans; Magnetic Resonance Imaging; Neoplasm Staging; Practice Guidelines as Topic; Preoperative Period; Rectal Neoplasms; Remission Induction; Republic of Korea; Article; cancer regression; chemoradiotherapy; comparative study; controlled study; diagnostic test accuracy study; diffusion weighted imaging; evidence based medicine; human; Korean medicine; major clinical study; meta analysis; nuclear magnetic resonance imaging; practice guideline; radiology; rectum cancer; reference database; sensitivity and specificity; systematic review; T2 weighted imaging; treatment response; watchful waiting; algorithm; cancer staging; chemoradiotherapy; diagnostic imaging; nuclear magnetic resonance imaging; pathology; preoperative period; rectum tumor; remission; South Korea English 2020 2020-07 10.3348/kjr.2020.0483 바로가기 바로가기 바로가기 바로가기
Article Multi-objective sustainable design model for integrating CO2 emissions and costs for slabs in office buildings Composite beams comprising concrete slabs supported by steel beams typically constitute more than 70% of the total volume of the structure of an office building. Little, if any, research has been conducted regarding the design and construction of a floor system that successfully accounts for eco-friendliness. To remedy this, an optimal sustainable design model for composite beams (OSDMCB) has been developed. The proposed OSDMCB was used to analyse the relationship between CO2 emissions and costs required for the construction of concrete slabs supported by steel beams composed of four different materials: concrete, steel frame, rebar, and a shear connector. To verify the performance of the OSDMCB, it was applied to the design and construction of composite beams in a 30-story office building. When both costs and CO2 emissions are simultaneously minimised, the composite beam of the OSDMCB, compared with a composite beam without the OSDMCB, reduces the costs and CO2 emissions by 6.23% and 4.07%, respectively. Lee, Min Gyu; An, Jung Hwan; Bae, Sang Geun; Oh, Hyung Seok; Choi, Jewoo; Yun, Da Yo; Hong, Taehoon; Lee, Dong-Eun; Park, Hyo Seon Yonsei Univ, Dept Architectural Engn, Seoul 120749, South Korea; Kyungpook Natl Univ, Sch Architecture & Civil & Architectural Engn, Daegu, South Korea ; Yun, Da Yo/JGL-9452-2023; Hong, Taehoon/E-9169-2012; Choi, Jewoo/MGT-4857-2025 57214536773; 57205458246; 57205453285; 57205459566; 57205453819; 57205454679; 57969349700; 56605563300; 55669886900 hspark@yonsei.ac.kr; STRUCTURE AND INFRASTRUCTURE ENGINEERING STRUCT INFRASTRUCT E 1573-2479 1744-8980 16 8 SCIE ENGINEERING, CIVIL;ENGINEERING, MECHANICAL 2020 3.087 35.7 0.58 2025-06-25 11 12 Multi-objective optimisation; slab system; sustainable structural design; office buildings; CO2 emissions CONCRETE FRAMES; EMBODIED ENERGY; SEISMIC DESIGN; CONSTRUCTION; OPTIMIZATION CO2 emissions; Multi-objective optimisation; office buildings; slab system; sustainable structural design Architectural design; Carbon dioxide; Composite beams and girders; Concrete beams and girders; Concrete slabs; Ecodesign; Multiobjective optimization; Office buildings; Steel beams and girders; Sustainable development; CO2 emissions; Composite beam; Design and construction; Floor systems; Multi objective; Shear connector; Slab systems; Steel frame; Structural design English 2020 2020-08-02 10.1080/15732479.2019.1683590 바로가기 바로가기 바로가기 바로가기
Article Numerical simulation of water content dependent undrained shear strength of clays A nonlinear mathematical model for estimating the water content dependent undrained shear strength of clayey soils was developed. Three types of clay mixtures (kaolinite, bentonite, and kaolinite-bentonite) were considered. The shear strength of the given soil samples was determined via torvane tests. Experimental results were compared with three numerical results: (i) the analytical function fit, (ii) modeling without the water content effect, and (iii) modeling with the water content effect using the Mohr-Coulomb (M-C) model. There was good agreement among the experimental, analytical, and numerical results with and without the water content effect in the fully softening zone. However, there was a large difference between the numerical results obtained from the developed model with and without the water content effect in the flow zone with a high liquidity index, because the shear strength may decrease significantly to low value in the case of an abrupt increase of the water content. The greatest advantage of the developed model is that it can simulate the reduction of the shear strength and shear band development under the high water content condition, which may trigger a large mobile mass movement. Park, Sung-Sik; Doan, Nhat-Phi; Jeong, Sueng Won Kyungpook Natl Univ, Dept Civil Engn, Daegu, South Korea; Korea Inst Geosci & Mineral Resources, Geol Environm Div, Daejeon, South Korea Doan, Nhat-Phi/IAM-1883-2023; DOAN, NHAT-PHI/IAM-1883-2023 36241850300; 58095587400; 35069425600 suengwon@hotmail.com; MARINE GEORESOURCES & GEOTECHNOLOGY MAR GEORESOUR GEOTEC 1064-119X 1521-0618 38 5 SCIE ENGINEERING, GEOLOGICAL;ENGINEERING, OCEAN;MINING & MINERAL PROCESSING;OCEANOGRAPHY 2020 2.673 35.7 0.68 2025-06-25 10 10 Undrained shear strength; clay; water content effect; modified Mohr-Coulomb model; torvane test FINITE-ELEMENT-ANALYSIS; SUBMARINE LANDSLIDES; PROPAGATION; SEDIMENT; BEHAVIOR; MODEL clay; modified Mohr-Coulomb model; torvane test; Undrained shear strength; water content effect Bentonite; Clay; Kaolinite; Shear strength; Analytical functions; Content dependent; High water content; Liquidity indices; Mohr Coulomb model; Nonlinear mathematical model; Numerical results; Undrained shear strength; clay soil; Coulomb criterion; experimental study; Mohr theory; numerical method; shear strength; undrained test; water content; Shear flow English 2020 2020-05-27 10.1080/1064119x.2019.1608604 바로가기 바로가기 바로가기 바로가기
Article Prognostic Implication of Volumetric Quantitative CT Analysis in Patients with COVID-19: A Multicenter Study in Daegu, Korea Objective: Lung segmentation using volumetric quantitative computed tomography (CT) analysis may help predict outcomes of patients with coronavirus disease (COVID-19). The aim of this study was to investigate the relationship between CT volumetric quantitative analysis and prognosis in patients with COVID-19. Materials and Methods: CT images from patients diagnosed with COVID-19 from February 18 to April 15, 2020 were retrospectively analyzed. CT with a negative finding, failure of quantitative analysis, or poor image quality was excluded. CT volumetric quantitative analysis was performed by automated volumetric methods. Patients were stratified into two risk groups according to CURB-65: mild (score of 0-1) and severe (2-5) pneumonia. Outcomes were evaluated according to the critical event-free survival (CEFS). The critical events were defined as mechanical ventilator care, ICU admission, or death. Multivariable Cox proportional hazards analyses were used to evaluate the relationship between the variables and prognosis. Results: Eighty-two patients (mean age, 63.1 +/- 14.5 years; 42 females) were included. In the total cohort, male sex (hazard ratio [Fin 9.264; 95% confidence interval [CI], 2.021-42.457; p = 0.004), C-reactive protein (CRP) (HR, 1.080 per mg/dL; 95% CI, 1.010-1.156; p = 0.025), and COVID-affected lung proportion (CALP) (HR, 1.067 per percentage; 95% CI, 1.033-1.101; p < 0.001) were significantly associated with CEFS. CRP (HR, 1.164 per mg/dL; 95% CI, 1.006-1.347; p = 0.041) was independently associated with CEFS in the mild pneumonia group (n = 54). Normally aerated lung proportion (NALP) (HR, 0.872 per percentage; 95% CI, 0.794-0.957; p = 0.004) and NALP volume (NALPV) (HR, 1.002 per mL; 95% CI, 1.000-1.004; p = 0.019) were associated with a lower risk of critical events in the severe pneumonia group (n = 28). Conclusion: CRP in the mild pneumonia group; NALP and NALPV in the severe pneumonia group; and sex, CRP, and CALP in the total cohort were independently associated with CEFS in patients with COVID-19. Park, Byunggeon; Park, Jongmin; Lim, Jae-Kwang; Shin, Kyung Min; Lee, Jaehee; Seo, Hyewon; Lee, Yong Hoon; Heo, Jun; Lee, Won Kee; Kim, Jin Young; Kim, Ki Beom; Moon, Sungjun; Choi, Sooyoung Kyungpook Natl Univ, Sch Med, Dept Radiol, 680 Gukchaebosang Ro, Daegu 41944, South Korea; Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Kyungpook Natl Univ Hosp, Med Res Collaborat Ctr, Daegu, South Korea; Keimyung Univ, Dept Radiol, Dongsan Hosp, Daegu, South Korea; Daegu Fatima Hosp, Dept Radiol, Daegu, South Korea; Yeungnam Univ, Coll Med, Dept Radiol, Daegu, South Korea; Yeungnam Univ, Dept Radiol, Med Ctr, Daegu, South Korea ; Lee, Jaehee/S-1697-2018; Kim, Juhee/KFS-3069-2024; Lee, Yoojin/AAB-9799-2022 57211532915; 57216463879; 55515341400; 7402410737; 13805476000; 55612130200; 57199022948; 36448170600; 22953484700; 55862597800; 59080545400; 57189891980; 57218715563 limjk@knu.ac.kr; KOREAN JOURNAL OF RADIOLOGY KOREAN J RADIOL 1229-6929 2005-8330 21 11 SCIE RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING 2020 3.5 35.7 1.56 2025-06-25 21 20 Volumetric quantitative analysis; Severe acute respiratory syndrome coronavirus 2; Coronavirus disease; Prognostic implication COMPUTED-TOMOGRAPHY Coronavirus disease; Prognostic implication; Severe acute respiratory syndrome coronavirus 2; Volumetric quantitative analysis Adult; Aged; Betacoronavirus; C-Reactive Protein; Coronavirus Infections; Female; Humans; Lung; Male; Middle Aged; Pandemics; Pneumonia, Viral; Prognosis; Proportional Hazards Models; Republic of Korea; Retrospective Studies; Severity of Illness Index; Tomography, X-Ray Computed; C reactive protein; C reactive protein; adult; aged; Article; cohort analysis; cone beam computed tomography; coronavirus disease 2019; covid affected lung proportion; covid affected lung proportion volume; CURB 65; densitometry; disease severity; erythrocyte sedimentation rate; female; follow up; human; image quality; image segmentation; Korea; leukocyte count; lung emphysema; lung volume; major clinical study; male; middle aged; mortality rate; multicenter study; normally aerated lung proportion; normally aerated lung proportion volume; pleura effusion; pneumonia; prognosis; quantitative analysis; radiation dose; retrospective study; reverse transcription polymerase chain reaction; sex difference; total lung capacity; virus pneumonia; Betacoronavirus; Coronavirus infection; diagnostic imaging; isolation and purification; lung; pandemic; prognosis; proportional hazards model; severity of illness index; South Korea; virology; virus pneumonia; x-ray computed tomography English 2020 2020-11 10.3348/kjr.2020.0567 바로가기 바로가기 바로가기 바로가기
Article Psychological distress among infectious disease physicians during the response to the COVID-19 outbreak in the Republic of Korea BackgroundThis study aimed to investigate psychological distress among infectious disease (ID) physicians during the coronavirus disease 2019 (COVID-19) outbreak in the Republic of Korea.MethodsUsing an online-based survey link sent via text message and email, we conducted a survey from April 21 to 25, 2020, targeting all ID physicians currently working in ID (n=265). The questionnaire was based on the Maslach Burnout Inventory-Human Services Survey and the Depression, Anxiety, and Stress Scales, and information was collected on factors protecting against psychological distress and difficulties in relation to COVID-19.ResultsOf 265 ID physicians, 115 (43.3%) responded, showing burnout (97, 90.4%), depression (20, 17.4%), anxiety (23, 20.0%), and stress (5, 4.3%). There were no differences in terms of distress between ID physicians who were directly involved in the care of patients with COVID-19 or not. Greater than 50% of physicians valued their work and felt recognized by others, whereas <10% indicated that sufficient human and financial support and private time had been provided during the outbreak. The most challenging issues concerned a lack of attending physicians caring for COVID-19 patients or infection control practitioners, a shortage of personal protective equipment or airborne infection isolation rooms, pressure for research, and lack of guidelines for COVID-19 management.ConclusionsDuring the COVID-19 outbreak in the Republic of Korea, most respondents reported psychological distress. Preparing strategies to secure human resources are crucial to prepare effectively for future epidemics and pandemics. Park, Se Yoon; Kim, Bongyoung; Jung, Dong Sik; Jung, Sook In; Oh, Won Sup; Kim, Shin-Woo; Peck, Kyong Ran; Chang, Hyun-Ha Soonchunhyang Univ, Coll Med, Seoul Hosp, Div Infect Dis,Dept Internal Med, Seoul, South Korea; Hanyang Univ, Coll Med, Dept Internal Med, Seoul, South Korea; Dong A Univ, Dept Internal Med, Coll Med, Div Infect Dis, Busan, South Korea; Chonnam Natl Univ, Med Sch, Dept Infect Dis, Gwangju, South Korea; Kangwon Natl Univ, Kangwon Natl Univ Hosp, Sch Med, Div Infect Dis,Dept Internal Med, Chunchon, South Korea; Kyungpook Natl Univ, Sch Med, Dept Internal Med, Div Infect Dis, 130 Dongdeok Ro, Daegu 41944, South Korea; Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Div Infect Dis, Seoul, South Korea ; JUNG, SOOK IN/AGO-2862-2022; Kim, Woo/AAG-1822-2019; Peck, Kyong Ran/AGV-5205-2022; OH, WON/AAK-8734-2021; Kim, Wonhee/AAA-1074-2021; Jung, Dong Sik/HOH-5826-2023 55259986400; 55622077200; 14023089600; 7403676835; 24778642500; 8710731500; 55664295200; 7407521688 changhha@knu.ac.kr; BMC PUBLIC HEALTH BMC PUBLIC HEALTH 1471-2458 20 1 SCIE PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH 2020 3.295 35.7 2.49 2025-06-25 24 30 COVID-19; Infectious diseases medicine; Burnout; Psychological; Psychological distress; South Korea BURNOUT Burnout; COVID-19; Infectious diseases medicine; Psychological; Psychological distress; South Korea Adult; Coronavirus Infections; Disease Outbreaks; Female; Humans; Infectious Disease Medicine; Male; Middle Aged; Pandemics; Physicians; Pneumonia, Viral; Psychological Distress; Republic of Korea; adult; Coronavirus infection; distress syndrome; epidemic; female; human; infectious disease medicine; male; middle aged; pandemic; physician; psychology; South Korea; virus pneumonia English 2020 2020-12-27 10.1186/s12889-020-09886-w 바로가기 바로가기 바로가기 바로가기
Correction Structural and Functional Features on Quantitative Chest Computed Tomography in the Korean Asian versus the White American Healthy Non-Smokers (vol 20, pg 1236, 2019) Cho, Hyun Bin; Chae, Kum Ju; Jin, Gong Yong; Choi, Jiwoong; Lin, Ching-Long; Hoffman, Eric A.; Wenzel, Sally E.; Castro, Mario; Fain, Sean B.; Jarjour, Nizar N.; Schiebler, Mark L.; Barr, R. Graham; Hansel, Nadia; Cooper, Christopher B.; Kleerup, Eric C.; Han, MeiLan K.; Woodruff, Prescott G.; Kanner, Richard E.; Bleecker, Eugene R.; Peters, Stephen P.; Moore, Wendy C.; Lee, Chang Hyun; Choi, Sanghun Kyungpook Natl Univ, Sch Mech Engn, Daegu, South Korea; Chonbuk Natl Univ, Chonbuk Natl Univ Hosp, Dept Radiol, Biomed Res Inst,Res Inst Clin Med, Jeonju, South Korea; Univ Iowa, Dept Mech Engn, Iowa City, IA 52242 USA; Univ Iowa, Dept Biomed Engn, Iowa City, IA 52242 USA; Univ Iowa, IIHR Hydrosci & Engn, Iowa City, IA 52242 USA; Univ Iowa, Coll Med, Dept Radiol, Iowa City, IA 52242 USA; Univ Pittsburgh, Div Pulm Allergy & Crit Care Med, Pittsburgh, PA USA; Washington Univ, Sch Med, Dept Internal Med, St Louis, MO 63110 USA; Washington Univ, Sch Med, Dept Pediat, St Louis, MO 63110 USA; Univ Wisconsin, Dept Radiol, Sch Med & Publ Hlth, Madison, WI 53706 USA; Univ Wisconsin, Dept Med, Sch Med & Publ Hlth, Madison, WI USA; Univ Wisconsin, Dept Med Phys & Biomed Engn, Madison, WI USA; Columbia Univ, Dept Med, Med Ctr, New York, NY USA; Columbia Univ, Dept Epidemiol, Med Ctr, New York, NY USA; Johns Hopkins Univ, Sch Med, Baltimore, MD USA; Univ Calif Los Angeles, Dept Physiol, Los Angeles, CA 90024 USA; Univ Calif Los Angeles, Dept Med, Los Angeles, CA 90024 USA; Univ Michigan, Dept Internal Med, Ann Arbor, MI 48109 USA; Univ Calif San Francisco, Sch Med, San Francisco, CA USA; Univ Utah, Sch Med, Salt Lake City, UT USA; Univ Arizona Hlth Sci, Dept Genet & Genom, Tucson, AZ USA; Univ Arizona Hlth Sci, Dept Precis Med, Tucson, AZ USA; Wake Forest Univ, Bowman Gray Sch Med, Dept Internal Med, Winston Salem, NC 27103 USA; Seoul Natl Univ Hosp, Dept Radiol, Seoul, South Korea ; Schiebler, Mark/V-5201-2019; Fain, Sean/K-4260-2016; Wenzel, Sally/ABY-1380-2022; Arınç, Sibel/ADP-9208-2022; Lee, Chang-Hoon/AAC-7650-2021; Choi, Sanghun/AGS-7430-2022; Castro, Mario/ABD-7776-2021; Fahy, John/ABS-1213-2022 57210022122; 57195310676; 55663719500; 55749525100; 8923593300; 58000586800; 7101833061; 7402292535; 7007034729; 7003501462; 7003277933; 23477164100; 58533627100; 7403318967; 6701488832; 12786822400; 35418932500; 7005898262; 7004832308; 7201537159; 7403101064; 57196253438; 55847101000 KOREAN JOURNAL OF RADIOLOGY KOREAN J RADIOL 1229-6929 2005-8330 21 1 SCIE RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING 2020 3.5 35.7 0 2025-06-25 0 0 erratum English 2020 2020-01 10.3348/kjr.2019.0912 바로가기 바로가기 바로가기 바로가기
Article Cure kinetics of low-molar-ratio urea-formaldehyde resins reinforced with modified nanoclay using different kinetic analysis methods This study reports on low-molar-ratio urea-formaldehyde (UF) resins modified with transition-metal-ion-modified bentonite (TMI-BNT) nanoclay assessed using different kinetic analysis methods in order to understand the effect of TMI-BNT on the cure kinetics of these modified resins. Differential scanning calorimetry was used to determine the kinetic parameters using two types of cure kinetic analysis: 1) model-fitting (MFT) methods, which include the Kissinger and nth-order approaches, and 2) model-free kinetics (MFK) methods, including the Friedman (FR), Flynn-Wall-Ozawa (FWO), and Kissinger-Akahira-Sunose (KAS) approaches. Of these kinetic methods, the Kissinger, FWO, and KAS approaches exhibited the best fit in terms of explaining the resins' curing behavior, showing that, in general, the apparent activation energy (E-a) decreased as TMI-BNT levels increased, which indicates that the curing process is accelerated by the addition of TMI-BNT. These results suggest that TMI-BNT is a potential additive for the effective acceleration of the curing of low-molar-ratio UF resins and may possibly improve their adhesion as well. In addition, according to the Malek method, it is found that UF resins curing behavior are likely to follow the autocatalytic nature of reaction. Wibowo, Eko Setio; Park, Byung-Dae Kyungpook Natl Univ, Dept Wood & Paper Sci, Daegu 41566, South Korea Wibowo, Eko/AAL-5888-2021; Park, Byung-Dae/ABB-1934-2020 57214910272; 7402834820 byungdae@knu.ac.kr; THERMOCHIMICA ACTA THERMOCHIM ACTA 0040-6031 1872-762X 686 SCIE CHEMISTRY, ANALYTICAL;CHEMISTRY, PHYSICAL;THERMODYNAMICS 2020 3.115 35.8 2.1 2025-06-25 37 38 Cure kinetics; UF resins; Modified nanoclay; Analysis method; Cure acceleration THERMAL CURING BEHAVIOR; WOOD; PARAMETERS; EMISSION; UF; ADHESIVES; PMDI Analysis method; Cure acceleration; Cure kinetics; Modified nanoclay; UF resins Activation Energy; Curing; Formaldehyde; Kinetics; Metabolism; Transition Metals; Activation energy; Curing; Differential scanning calorimetry; Formaldehyde; Kinetics; Metabolism; Metal ions; Molar ratio; Nanocomposites; Polymer blends; Resins; Transition metal compounds; Transition metals; Urea; Analysis method; Apparent activation energy; Cure kinetics; Flynn-Wall-Ozawa; Model free kinetics; Modified bentonites; Nano clays; Urea formaldehyde; Urea formaldehyde resins English 2020 2020-04 10.1016/j.tca.2020.178552 바로가기 바로가기 바로가기 바로가기
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