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WoS SCOPUS Document Type Document Title Abstract Authors Affiliation ResearcherID (WoS) AuthorsID (SCOPUS) Author Email(s) Journal Name JCR Abbreviation ISSN eISSN Volume Issue WoS Edition WoS Category JCR Year IF JCR (%) FWCI FWCI Update Date WoS Citation SCOPUS Citation Keywords (WoS) KeywordsPlus (WoS) Keywords (SCOPUS) KeywordsPlus (SCOPUS) Language Publication Stage Publication Year Publication Date DOI JCR Link DOI Link WOS Link SCOPUS Link
Article Cu-ion-actuated three-terminal neuromorphic synaptic devices based on binary metal-oxide electrolyte and channel An analogous change in lateral channel current from source to drain in three-terminal synaptic devices actuated by mobile ions vertically provided from a gate can enhance neuromorphic computing performances. We demonstrate a gradually tuned channel current in a fully complementary metal-oxide-semiconductor compatible HfOx/WOx stack with Cu ions. By examining each layer in the three-terminal device, such as the channel, electrolyte, and mobile ion supplier, we identify which device structure can modulate the channel current effectively using mobile ions. Our findings reveal that the gate-tunable channel current response can be solely achieved when the Cu ions are not locally formed but migrate throughout the HfOx electrolyte. The linear dependence of the analog current operation on the channel width further proves the area-switching mechanism. The importance of ion movement can be indirectly verified from the uncontrollable channel currents using either Ag ions with faster mobility than Cu ions or a local path is created because of the thinned HfOx electrolyte. Kang, Heebum; Woo, Jiyong Kyungpook Natl Univ, Sch Elect Engn, Daegu 41566, South Korea; Kyungpook Natl Univ, Sch Elect & Elect Engn, Daegu 41566, South Korea 57232405900; 53985749100 jiyong.woo@knu.ac.kr; APPLIED PHYSICS LETTERS APPL PHYS LETT 0003-6951 1077-3118 119 7 SCIE PHYSICS, APPLIED 2021 3.971 30.8 1.4 2025-07-30 19 16 RESISTIVE MEMORY CMOS integrated circuits; Copper; Drain current; Hafnium compounds; Heavy ions; Ionic conduction; MOS devices; Oxide semiconductors; Binary metal oxides; Channel currents; Channel widths; Complementary metal-oxide-semiconductor compatible; Linear dependence; Neuromorphic computing; Switching mechanism; Three-terminal devices; Electrolytes English 2021 2021-08-16 10.1063/5.0059697 바로가기 바로가기 바로가기 바로가기
Article Effect of defect interactions with interstitial Ag in the lattice of BixSb2-xTe3 alloys and their thermoelectric properties In this study, the effect of Ag defects on the lattice and thermoelectric properties of Ag-doped BixSb2-xTe3 (BST) alloys are systematically investigated. Using density-functional calculations, we reveal that Ag impurity defects occupying interstitial sites in the BST affect the formation of intrinsic defects in the host materials. Ag interstitial defects, which are responsible for increasing the lattice parameter of the c axis, lower the formation energies of Bi-Te and Sb-Te acceptor defects more effectively in the Bi-rich BST than in the Bi-poor BST. In addition, these Ag interstitials induce the formation of Ag-Bi and Ag-Sb in BixSb2-xTe3. Therefore, Ag-induced defect interactions can be used to finely optimize the defects and doping density by varying the Bi content. Furthermore, the phonon thermal conductivity is reduced with the formation of nanoscale twin structures with various stacking faults. Finally, a high figure of merit of 1.4 at 423K is achieved for p-type BST alloys. Lee, Jae Ki; Park, Sungjin; Ryu, Byungki; Lee, Ho Seong; Park, Jongho; Park, SuDong Korea Elect Res Inst, Energy Convers Res Ctr, Chang Won 51543, South Korea; Kyungpook Natl Univ, Sch Mat Sci & Engn, Daegu 41566, South Korea Lee, Jae Ki/GPX-5184-2022; Park, Sungjin/D-7977-2011; Ryu, Byungki/F-7050-2010 35303113300; 57210251132; 16242305700; 55706810400; 59699976400; 12800088700 jackyrhy@keri.re.kr;sjinpark@keri.re.kr; APPLIED PHYSICS LETTERS APPL PHYS LETT 0003-6951 1077-3118 118 5 SCIE PHYSICS, APPLIED 2021 3.971 30.8 1.2 2025-07-30 13 13 PERFORMANCE; FIGURE; MERIT; VASP; PBTE Binary alloys; Silver; Thermoelectric equipment; Thermoelectricity; Defect interactions; Formation energies; Interstitial defects; Interstitial sites; Intrinsic defects; Nano-scale twins; Phonon thermal conductivity; Thermoelectric properties; Bismuth alloys English 2021 2021-02-01 10.1063/5.0040808 바로가기 바로가기 바로가기 바로가기
Article Hormone Receptor Subtype in Ductal Carcinoma in Situ: Prognostic and Predictive Roles of the Progesterone Receptor Background We investigated the prognostic and predictive roles of the hormone receptor (HRc) subtype in patients with ductal carcinoma in situ (DCIS). We focused on identifying the roles of the progesterone receptor (PR) independent of estrogen receptor (ER) status. Methods Nationwide data of 12,508 female patients diagnosed with DCIS with a mean follow-up period of 60.7 months were analyzed. HRc subtypes were classified as ER-/PR-, ER-/PR+, ER+/PR-, and ER+/PR+ based on ER and PR statuses. The Cox proportional hazards model was used to calculate hazard ratios (HRs) and 95% confidence intervals (CIs). Results The ER+/PR+ group showed better prognoses than the ER+/PR- and ER-/PR- groups in the patients who received tamoxifen therapy (p = .001 and p = .031, respectively). HRc subtype was an independent prognostic factor (p = .028). The tamoxifen therapy group showed better survival than the patients who did not receive tamoxifen, but only in the ER+/PR+ subgroup (p = .002). Tamoxifen therapy was an independent prognostic factor (HR, 0.619; 95% CI, 0.423 - 0.907; p = .014). PR status was a favorable prognostic factor in patients with DCIS who received tamoxifen therapy (p < .001), and it remained a prognostic factor independent of ER status (HR, 0.576; 95% CI, 0.349 - 0.951; p = .031). Conclusion The HRc subtype can be used as both a prognostic and predictive marker in patients with newly diagnosed DCIS. Tamoxifen therapy can improve overall survival in the ER+/PR+ subtype. PR status has significant prognostic and predictive roles independent of ER status. Testing for the PR status in addition to the ER status is routinely recommended in patients with DCIS to determine the HRc subtype in clinical settings. Implications for Practice The hormone receptor (HRc) subtype was an independent prognostic factor, and the estrogen receptor (ER)+/progesterone receptor (PR) + subtype showed a better survival in patients with ductal carcinoma in situ (DCIS) who received tamoxifen therapy. PR was an independent prognostic factor independent of ER, and PR was a favorable prognostic factor in patients with DCIS who received tamoxifen therapy. The HRc subtype could be used as both a prognostic and predictive marker in patients with newly diagnosed DCIS. Testing of PR status in addition to ER status is routinely recommended for patients with DCIS to determine the HRc subtype in clinical settings. Hwang, Ki-Tae; Suh, Young Jin; Park, Chan-Heun; Lee, Young Joo; Kim, Jee Ye; Jung, Jin Hyang; Kim, Seeyeong; Min, Junwon Seoul Natl Univ, Seoul Metropolitan Govt, Dept Surg, Coll Med, Seoul, South Korea; Catholic Univ Korea, Dept Surg, St Vincents Hosp, Seoul, South Korea; Sungkyunkwan Univ, Dept Surg, Sch Med, Seoul, South Korea; Asan Med Ctr, Dept Surg, Seoul, South Korea; Yonsei Univ, Dept Surg, Coll Med, Seoul, South Korea; Kyungpook Natl Univ, Dept Surg, Sch Med, Daegu, South Korea; SaeGyaeRo Hosp, Dept Surg, Busan, South Korea; Dankook Univ, Dept Surg, Coll Med, Cheonan, South Korea ; SUH, YOUNG JIN/N-9046-2016; KIM, SEON-OK/HGC-7012-2022; Lee, Jong-Mok/KVY-9550-2024 57197884861; 57202964270; 57200867768; 58019185800; 56666476900; 57209310173; 57389148600; 36182527600 kiterius@snu.ac.kr; ONCOLOGIST ONCOLOGIST 1083-7159 1549-490X 26 11 SCIE ONCOLOGY 2021 5.837 30.8 0.34 2025-07-30 4 4 Breast neoplasms; Ductal carcinoma in situ; Estrogen receptor; Hormone receptor subtype; Progesterone receptor INVASIVE BREAST-CANCER; SURGICAL ADJUVANT BREAST; AMERICAN SOCIETY; CLINICAL ONCOLOGY/COLLEGE; ESTROGEN; WOMEN; TAMOXIFEN; THERAPY; DCIS; RECOMMENDATIONS Breast neoplasms; Ductal carcinoma in situ; Estrogen receptor; Hormone receptor subtype; Progesterone receptor Carcinoma, Intraductal, Noninfiltrating; Female; Hormones; Humans; Prognosis; Receptors, Progesterone; epidermal growth factor receptor; estrogen receptor; hormone receptor; progesterone receptor; tamoxifen; hormone; progesterone receptor; adolescent; adult; aged; Article; body mass; cancer patient; cancer prognosis; cancer radiotherapy; cancer staging; child; controlled study; cox proportional hazard; data base; ductal breast carcinoma in situ; evaluation and follow up; female; follow up; hazard ratio; human; immunohistochemistry; Kaplan Meier method; Korean Breast Cancer Registry database; lumpectomy; lymph node dissection; major clinical study; mastectomy; middle aged; mortality; multivariate analysis; overall survival; pathology; practice guideline; predictive value; preschool child; prognostic assessment; proportional hazards model; survival analysis; univariate analysis; very elderly; genetics; intraductal carcinoma; prognosis English 2021 2021-11 10.1002/onco.13938 바로가기 바로가기 바로가기 바로가기
Article Hybrid memory characteristics of NbOx threshold switching devices By exploiting NbOx, we demonstrate its hybrid memory characteristics, indicating that resistive switching is unified with selector behavior. First, we identify that the 50-nm-thick amorphous NbOx inherently shows volatile threshold switching (TS). To enable memory switching (MS) in NbOx, device environments are configured that can supply oxygen vacancies or cations constituting a conductive filament (CF). In the Al/NbOx/TiN stack, oxygen vacancies can be internally generated from an interfacial oxide layer formed by the chemical reaction between a highly reactive Al electrode and NbOx, which is confirmed via multiple physical analyses. When the effect of the extrinsic vacancies becomes comparable to the intrinsic properties of the NbOx, the hybrid memory characteristics are observed. While the TS prevents leakage current, the MS is driven by oxygen vacancy CF, allowing multilevel cell operation. Furthermore, hybrid switching can be obtained using the Cu/NbOx/TiN stack. However, the effect of a Cu CF is dominant, because the Cu electrode can externally provide ions infinitely in this case; therefore, hybrid memory behavior is achieved after MS is performed. Lee, Sangmin; Hwang, Hyunsang; Woo, Jiyong Pohang Univ Sci & Technol, Dept Mat Sci & Engn, Pohang 37673, South Korea; Kyungpook Natl Univ, Sch Elect Engn, Daegu 41566, South Korea 57254918800; 7403258319; 53985749100 hwanghs@postech.ac.kr;jiyong.woo@knu.ac.kr; APPLIED PHYSICS LETTERS APPL PHYS LETT 0003-6951 1077-3118 119 9 SCIE PHYSICS, APPLIED 2021 3.971 30.8 0.7 2025-07-30 6 7 SELECTOR; ARRAYS Chemical analysis; Copper; Electrodes; Niobium compounds; Oxygen supply; Switching; Conductive filaments; Hybrid-switching; Interfacial oxide layers; Intrinsic property; Physical analysis; Resistive switching; Switching devices; Threshold switching; Oxygen vacancies English 2021 2021-08-30 10.1063/5.0061435 바로가기 바로가기 바로가기 바로가기
Article Low thermal conductivity in GeTe-based thermoelectric materials with additional activated carbon In order to improve the performance of thermoelectric materials, nanoinclusions are often used to enhance phonon scattering. In this study, activated carbon, which is porous and thus has a large surface area, was incorporated in GeTe-based materials to cause increased boundary phonon scattering. Carbon dispersed in grain boundaries resulted in improved thermal properties without significant deterioration in electrical properties. Due to the extrinsic addition of activated carbon, the lattice thermal conductivity decreased by 13.8% on average. A maximum dimensionless figure of merit of 1.66 was achieved at 723K for the Ge0.9Sb0.1Te composition with additional activated carbon. Youn, Jimin; Ryu, Juhee; Kim, Hyunji; Kihoi, Samuel Kimani; Son, In-Sik; Chun, Sang-Eun; Yi, Seonghoon; Lee, Ho Seong Kyungpook Natl Univ, Sch Mat Sci & Engn, 80 Daehak Ro, Daegu 41566, South Korea Kihoi, Samuel Kimani/IUM-8515-2023; Yi, Seonghoon/HGC-6912-2022 57221833089; 57221836336; 57208408040; 57208396874; 57212529007; 36801080300; 14008383000; 55706810400 hs.lee@knu.ac.kr; APPLIED PHYSICS LETTERS APPL PHYS LETT 0003-6951 1077-3118 118 5 SCIE PHYSICS, APPLIED 2021 3.971 30.8 1.2 2025-07-30 15 15 Activated carbon; Antimony compounds; Deterioration; Germanium compounds; Grain boundaries; Phonon scattering; Phonons; Tellurium compounds; Thermoelectric equipment; Thermoelectricity; Dimensionless figure of merit; Large surface area; Lattice thermal conductivity; Low thermal conductivity; Nano inclusion; Significant deteriorations; Thermo-Electric materials; Thermal conductivity English 2021 2021-02-01 10.1063/5.0039883 바로가기 바로가기 바로가기 바로가기
Article 2021 Roadmap: electrocatalysts for green catalytic processes Serious challenges in energy and the environment require us to find solutions that use sustainable processes. There are many sustainable electrocatalytic processes that might provide the answers to the above-mentioned challenges, such as the oxygen reduction reaction (ORR), water splitting, the carbon dioxide reduction reaction (CO2RR), and the nitrogen reduction reaction (NRR). These reactions can enhance the value added by producing hydrogen energy through water splitting or convert useless CO2 and N-2 into fuels and NH3. These electrocatalytic reactions can be driven by high-performance catalysts. Therefore, the exploration of novel electrocatalysts is one of the important electrocatalytic fields. In this paper, we aim to systematically discuss a variety of electrocatalysts used for sustainable processes and to give further insights into their status and associated challenges. We invited many famous research groups to write this roadmap with topics including platinum (Pt) and its alloys for ORR, oxides for ORR, chalcogenides for ORR, carbon-based hollow electrocatalysts for ORR, carbides for ORR, atomically dispersed Fe-N-C catalysts for ORR, metal-free catalysts for ORR, single-atom catalysts (SACs) for ORR, metal boride (MB) electrocatalysts for water splitting, transitional metal carbides (TMCs) for water splitting, transition metal (TM) phosphides for water splitting, oxides for water splitting, sulfides for water splitting, layered double hydroxides for water splitting, carbon-based electrocatalysts for water splitting, Ru-based electrocatalysts for water splitting, metal oxides for CO2RR, metal sulfides for CO2RR, metals for CO2RR, carbon for CO2RR, SACs for CO2RR, heterogeneous molecular catalysts for CO2RR, oxides for NRR, chalcogenides for NRR, C3N4 for NRR, SACs for NRR, etc. Their contributions enabled us to compile this 2020 roadmap on electrocatalysts for green catalytic processes and provide some suggestions for future researchers. Liu, Jiandong; Ma, Jianmin; Zhang, Zhicheng; Qin, Yuchen; Wang, Yan-Jie; Wang, Yao; Tan, Rou; Duan, Xiaochuan; Tian, Tong Zhen; Zhang, Cai Hong; Xie, Wen Wen; Li, Nian-Wu; Yu, Le; Yang, Chenhuai; Zhao, Yanyan; Zia, Hamna; Nosheen, Farhat; Zheng, Guangchao; Gupta, Suraj; Wu, Xianhong; Wang, Zhiyu; Qiu, Jieshan; Zhou, Guangyao; Xu, Lin; Liu, Kang; Fu, Junwei; Liu, Min; Choi, Sang-Il; Xie, Junfeng; Peng, Xinwen; Li, Tingzhen; Lin, Gaoxin; Wang, Jiacheng; Han, Jingrui; Liang, Hongyan; Li, Shuyu; Zhang, Xiaotao; Zhu, Yating; He, Ting; Cui, Xiaoya; Wang, Haiqing; Wei, Zengxi; Liu, Quanhui; Fan, Guangyin; Liu, Qian; Sun, Xuping; Feng, Yuezhan; Liu, Yaping; Chu, Ke; Qiu, Yuan; Liu, Xijun Hunan Univ, Sch Phys & Elect, Changsha 410082, Peoples R China; Tianjin Univ, Sch Sci, Dept Chem, Tianjin Key Lab Mol Optoelect Sci, Tianjin 300072, Peoples R China; Collaborat Innovat Ctr Chem Sci & Engn, Tianjin 300072, Peoples R China; Henan Agr Univ, Coll Sci, Zhengzhou 450000, Peoples R China; Dongguan Univ Technol, Sch Mat Sci & Engn, 1 Daxue Rd, Dongguan 523808, Guangdong, Peoples R China; China Univ Petr, Coll Chem Engn & Environm, State Key Lab Heavy Oil Proc, Beijing 102249, Peoples R China; Xiamen Univ, Pen Tung Sah Inst Micronano Sci & Technol, Xiamen 361005, Peoples R China; Beijing Univ Chem Technol, State Key Lab Organ Inorgan Composites, Beijing 100029, Peoples R China; Boston Coll, Merkert Chem Ctr, Dept Chem, 2609 Beacon St, Chestnut Hill, MA 02467 USA; Int Islamic Univ Islamabad, SA CIRBS, Islamabad, Pakistan; Univ Educ, Dept Chem, Div Sci & Technol, Lahore, Pakistan; Zhengzhou Univ, Sch Phys & Microelect, Zhengzhou 450001, Henan, Peoples R China; Univ Liverpool, Sch Engn, Liverpool L69 3GH, Merseyside, England; Dalian Univ Technol, State Key Lab Fine Chem, Liaoning Key Lab Energy Mat & Chem Engn, Dalian 116024, Peoples R China; Nanjing Normal Univ, Sch Chem & Mat Sci, Jiangsu Key Lab New Power Batteries, Nanjing 210023, Peoples R China; Cent South Univ, Sch Phys & Elect, Changsha 410083, Peoples R China; Kyungpook Natl Univ, Dept Chem, Daegu 41566, South Korea; Kyungpook Natl Univ, Green Nano Mat Res Ctr, Daegu 41566, South Korea; Shandong Normal Univ, Coll Chem Chem Engn & Mat Sci, Jinan 250014, Peoples R China; South China Univ Technol, State Key Lab Pulp & Paper Engn, Guangzhou 510641, Peoples R China; Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, Shanghai 200050, Peoples R China; Tianjin Univ, Sch Mat Sci & Engn, Tianjin 300350, Peoples R China; Nanyang Technol Univ, Ctr Programmable Mat, Sch Mat Sci & Engn, 50 Nanyang Ave, Singapore 639798, Singapore; Univ Jinan, Collaborat Innovat Ctr Technol & Equipment Biol D, Inst Adv Interdisciplinary Res iAIR, Jinan 250022, Peoples R China; Univ Elect Sci & Technol China, Inst Fundamental & Frontier Sci, Chengdu 610054, Peoples R China; Sichuan Normal Univ, Coll Chem & Mat Sci, Chengdu 610068, Sichuan, Peoples R China; Zhengzhou Univ, Minist Educt, Key Lab Mat Proc & Mold, Zhengzhou 450002, Peoples R China; Lanzhou Jiaotong Univ, Sch Mat Sci & Engn, Lanzhou 730070, Peoples R China; Tianjin Univ Technol, Sch Mat Sci & Engn, Inst New Energy Mat & Low Carbon Technol, Tianjin Key Lab Adv Funct Porous Mat, Tianjin 300384, Peoples R China ; Duan, Xiaochuan/S-1026-2018; Fan, Guangyin/EOD-4512-2022; Zhu, Yating/MFI-2511-2025; lin, gaoxin/ABC-6762-2022; Fu, Junwei/KFB-7060-2024; Wang, Zhiyu/G-3762-2014; Ting, He/HJI-1623-2023; liu, xijun/AGY-4250-2022; Li, Nian-Wu/AAM-8788-2021; Nosheen, Farhat/IUP-8552-2023; Wang, Haiqing/ABD-5775-2021; Liu, Qian/ABB-4651-2020; Zhou, Guangyao/AAH-7519-2019; Choi, Sang-Il/AGR-1133-2022; YU, LE/B-7784-2013; Liang, Hongyan/D-7087-2016; Liang, Hongyan/B-4884-2019; Liu, Min/ABI-4990-2020; Feng, Yuezhan/JOZ-4614-2023; Ma, Jianmin/M-5217-2013; Zheng, Guangchao/AAR-5940-2020; Gupta, Suraj/K-7774-2016; Zhang, Zhicheng/AAQ-2833-2020; wang, Jiacheng/A-8458-2008; Sun, Xuping/T-7163-2018; Xie, Junfeng/A-9215-2010; Chu, Ke/I-7418-2012; Qiu, Jieshan/C-6276-2013; LIU, XIJUN/AGY-4250-2022; xiaotao, zhang/HGC-2346-2022 57204016823; 57203906041; 56174456600; 56522128000; 56084250800; 58973564600; 57207307233; 35310280900; 57220169493; 57220963429; 57220960286; 35424297400; 54783931300; 57217092810; 36678621500; 57223026750; 37561760200; 56591264700; 57209265343; 57194106710; 36519779200; 55479331800; 57201700034; 57207871363; 59601579700; 56185888400; 56484902300; 57223027673; 55478252600; 36133724200; 15020864100; 56949614800; 7701316612; 57203488921; 59287824500; 57217096271; 37113534600; 57214466386; 57199841597; 57196716940; 57211368206; 57194636099; 26642992200; 10243872200; 57204325124; 22939817400; 55975338500; 57203555692; 14033009300; 57208922700; 36834235700 nanoelechem@hnu.edu.cn;zczhang19@tju.edu.cn; JOURNAL OF PHYSICS-MATERIALS J PHYS-MATER 2515-7639 4 2 SCIE MATERIALS SCIENCE, MULTIDISCIPLINARY 2021 5.847 30.9 1.88 2025-07-30 84 81 oxygen reduction reaction; water splitting; nitrogen reduction reaction; carbon oxide reduction reaction; oxides; sulfides; metals OXYGEN REDUCTION REACTION; LAYERED DOUBLE HYDROXIDES; SINGLE-ATOM CATALYSTS; N-DOPED CARBON; STABLE BIFUNCTIONAL ELECTROCATALYST; ELECTROCHEMICAL CO2 REDUCTION; HYDROGEN EVOLUTION; NITROGEN REDUCTION; HIGH-PERFORMANCE; N-2 REDUCTION carbon oxide reduction reaction; metals; nitrogen reduction reaction; oxides; oxygen reduction reaction; sulfides; water splitting Ammonia; Carbides; Carbon Dioxide; Electrolysis; Phosphorus Compounds; Precious Metals; Ammonia; Carbides; Carbon dioxide; Carbon dioxide process; Chalcogenides; Electrocatalysis; Electrocatalysts; Electrolysis; Electrolytic reduction; Hydrogen fuels; Hydrogen production; Phosphorus compounds; Platinum alloys; Platinum metals; Pollution control; Sulfur compounds; Transition metal compounds; Transition metals; Carbon dioxide reduction; Electrocatalytic process; Electrocatalytic reactions; Energy and the environment; Layered double hydroxides; Metal-free catalysts; Molecular catalysts; Transitional metal carbides; Oxygen reduction reaction English 2021 2021-04 10.1088/2515-7639/abd596 바로가기 바로가기 바로가기 바로가기
Article Biased self-estimation of maths competence and subsequent motivation and achievement: differential effects for high- and low-achieving students The present study investigated whether self-estimation bias in maths competence was associated with motivational costs or benefits, concurrently and prospectively, and whether these associations depended on students' achievement levels. Participants were 2,807 seventh grade students who were reassessed after 2 years to examine the longitudinal effects on motivation and achievement attributable to overestimation of their own competence. It was found that high-achieving students experienced short-term as well as long-term benefits with overestimation, although motivational benefits flattened out and no further benefit was observed after an optimal level of overestimation. However, low-achieving students experienced short-term motivational benefits even with extreme overestimation, but these short-term benefits resulting from extreme overestimation turned out to be a 'poisoned chalice' without the skills and knowledge to bolster the inflated self-confidence. Lee, Eunju J. Kyungpook Natl Univ, Dept Educ, Daegu 702701, South Korea 55491752300 elee@knu.ac.kr; EDUCATIONAL PSYCHOLOGY EDUC PSYCHOL-UK 0144-3410 1469-5820 41 4 SSCI EDUCATION & EDUCATIONAL RESEARCH;PSYCHOLOGY, EDUCATIONAL 2021 3.117 30.9 0.43 2025-07-30 5 5 Self-estimation biases; positive illusion; overestimation; interest; engagement POSITIVE ILLUSIONS; EFFICACY BELIEFS; DARK SIDE; INDIVIDUAL-DIFFERENCES; SOCIAL COMPETENCE; ENHANCEMENT; SCHOOL; ACCURACY; MATHEMATICS; CONSEQUENCES engagement; interest; overestimation; positive illusion; Self-estimation biases English 2021 2021-04-21 10.1080/01443410.2020.1821869 바로가기 바로가기 바로가기 바로가기
Article A Comprehensive Study of Dynamic Recrystallization Behavior of Mg Alloy with 3 wt.% Bi Addition The effect of the addition of bismuth on the dynamic recrystallization (DRX) behavior of the matrix has been investigated by comparing coarse grain pure Mg with the addition of 3 wt.% Bi, using a uniaxial compression test in the temperature range of 473-623 K and the strain rate of 0.01-10 s(-1). The constitutive equation, processing map, microstructure, and texture evolution of the Mg-3Bi alloy were systematically investigated. The results showed that the Bi addition could refine the grain size and accelerate the DRX process. The DRX kinetics is discussed in detail, accompanied by extensive characterization employing EBSD analysis. The DRX of the Mg-3Bi alloy depended on the deformation temperature rather than the strain rate. The {10-12} tensile twin appeared at 573 K/0.01-0.1 s(-1), and discontinuous DRX (DDRX), continuous DRX (CDRX) as the main mechanism in the case of 573 K/0.01 s(-1), while the dominant mechanism was DDRX when deformation temperature and strain rate increased. Particle-stimulated nucleation (PSN) was also involved in the DRX of this new RE-free Mg alloy. Yu, Hui; Liu, Hao; Jiang, Binan; Yu, Wei; Kang, Shaoming; Cheng, Weili; Park, Sunghyuk; Chen, Dong; Yin, Fuxing; Shin, Kwangseon; Mu, Jinyao; Cui, Xiongwei; Li, Jianghai Hebei Univ Technol, Sch Mat Sci & Engn, Tianjin 300130, Peoples R China; PLA AAAAD, Hefei 230031, Peoples R China; Hefei Univ Technol, Sch Mat Sci & Engn, Hefei 200039, Peoples R China; Taiyuan Univ Technol, Sch Mat Sci & Engn, Taiyuan 030024, Peoples R China; Kyungpook Natl Univ, Sch Mat Sci & Engn, Daegu 41566, South Korea; Seoul Natl Univ, Magnesium Technol Innovat Ctr, Seoul 08826, South Korea; Tianjin Dongyi Magnesium Prod Co Ltd, Tianjin 301700, Peoples R China yu, hui/H-8481-2012; Shin, Kwang Seon/AAE-6177-2021; Yu, Wei/HHR-9148-2022; Yin, Fuxing/AAE-4626-2020; Yu, Hui/H-8481-2012 7405855938; 57218675781; 57061440600; 57221964647; 56877955700; 36466087600; 54786002500; 57226048361; 7202679517; 26430446200; 57223808339; 57223814741; 57223839695 huiyu@vip.126.com;18447071543@163.com;sympathy1988@163.com;yuwei52213@163.com;kangdashao@163.com;chengweili7@126.com;shpark@kims.re.kr;chendong19832021@163.com;yinfuxing@hebutedu.cn;ksshin@snu.ac.kr;jinyao@dongyimg.com;pm01@dongyimg.com;rdc11@dongyimg.com; METALS METALS-BASEL 2075-4701 11 5 SCIE MATERIALS SCIENCE, MULTIDISCIPLINARY;METALLURGY & METALLURGICAL ENGINEERING 2021 2.695 31.0 0.66 2025-07-30 13 14 Mg alloy; Bi addition; dynamic recrystallization; microstructure HOT DEFORMATION-BEHAVIOR; HIGH-TEMPERATURE DEFORMATION; MICROSTRUCTURAL EVOLUTION; CONSTITUTIVE ANALYSIS; MAGNESIUM ALLOYS; PROCESSING MAP; WORKABILITY; DISLOCATIONS; SEGREGATION; AZ31 Bi addition; Dynamic recrystallization; Mg alloy; Microstructure English 2021 2021-05 10.3390/met11050838 바로가기 바로가기 바로가기 바로가기
Article Deep-learning for predicting C-shaped canals in mandibular second molars on panoramic radiographs Objective: The aim of this study was to evaluate the use of a convolutional neural network (CNN) system for predicting C-shaped canals in mandibular second molars on panoramic radiographs. Methods: Panoramic and cone beam CT (CBCT) images obtained from June 2018 to May 2020 were screened and 1020 patients were selected. Our dataset of 2040 sound mandibular second molars comprised 887 C-shaped canals and 1153 non-C-shaped canals. To confirm the presence of a C-shaped canal, CBCT images were analyzed by a radiologist and set as the gold standard. A CNN-based deep-learning model for predicting C-shaped canals was built using Xception. The training and test sets were set to 80 to 20%, respectively. Diagnostic performance was evaluated using accuracy, sensitivity, specificity, and precision. Receiver-operating characteristics (ROC) curves were drawn, and the area under the curve (AUC) values were calculated. Further, gradient-weighted class activation maps (Grad-CAM) were generated to localize the anatomy that contributed to the predictions. Results: The accuracy, sensitivity, specificity, and precision of the CNN model were 95.1, 92.7, 97.0, and 95.9%, respectively. Grad-CAM analysis showed that the CNN model mainly identified root canal shapes converging into the apex to predict the C-shaped canals, while the root furcation was predominantly used for predicting the non-C-shaped canals. Conclusions: The deep-learning system had significant accuracy in predicting C-shaped canals of mandibular second molars on panoramic radiographs. Jeon, Su-Jin; Yun, Jong-Pil; Yeom, Han-Gyeol; Shin, Woo-Sang; Lee, Jong-Hyun; Jeong, Seung-Hyun; Seo, Min-Seock Wonkwang Univ, Dept Conservat Dent, Daejeon Dent Hosp, Daejeon, South Korea; Korea Inst Ind Technol KITECH, Safety Syst Res Grp, Gyongsan, South Korea; Wonkwang Univ, Dept Oral & Maxillofacial Radiol, Daejeon Dent Hosp, Daejeon, South Korea; Kyungpook Natl Univ, Coll IT Engn, Sch Elect Engn, Daegu, South Korea Lee, jaeho/ABE-6242-2020 57225020258; 16644164300; 57208645237; 57221727628; 57221622970; 57219224526; 17339394800 profee@naver.com; DENTOMAXILLOFACIAL RADIOLOGY DENTOMAXILLOFAC RAD 0250-832X 1476-542X 50 5 SCIE DENTISTRY, ORAL SURGERY & MEDICINE;RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING 2021 3.525 31.0 5.56 2025-07-30 42 47 Deep learning; Convolutional neural network; C-shaped canal; Diagnostic imaging; Panoramic radiograph PART I; 2ND-MOLARS; POPULATION; SYSTEMS C-shaped canal; Convolutional neural network; Deep learning; Diagnostic imaging; Panoramic radiograph Cone-Beam Computed Tomography; Deep Learning; Dental Pulp Cavity; Humans; Mandible; Molar; Radiography, Panoramic; Tooth Root; cone beam computed tomography; dental pulp cavity; diagnostic imaging; human; mandible; molar tooth; panoramic radiography; tooth root English 2021 2021 10.1259/dmfr.20200513 바로가기 바로가기 바로가기 바로가기
Article Environmentally Benign Organic Dye Conversion under UV Light through TiO2-ZnO Nanocomposite In this work, we developed a very simple and novel approach for synthesizing TiO2-ZnO nanocomposites via the urea-assisted thermal decomposition of titanium oxysulphate and zinc acetate at different weight ratios. The synthesized nanocomposite samples were studied by means of HR-TEM, XRD, STEM, UV-Vis DRS, PL and EDS. The observed results demonstrate that the TiO2-ZnO nanocomposite consists of an anatase crystal phase of TiO2 with a crystallite size of 10-15 nm. Combined characterization, including UV-Vis DRS, STEM, EDS and HR-TEM, revealed the successful formation of a heterojunction between TiO2 and ZnO and an improvement in UV spectrum absorption. The photocatalytic activity was explored using MO degradation under ultraviolet light illumination. The results of the optimized TiO2-ZnO nanocomposite show excellent photocatalytic activity and photostability over a number of degradation reaction cycles. In addition, the current approach has immense potential to be used as a proficient method for synthesizing mixed metal oxide nanocomposites. Deshmukh, Sandip M.; Arbuj, Sudhir S.; Babar, Santosh B.; Shaikh, Shoyebmohamad F.; Tamboli, Asiya M.; Nguyen Truong, Nguyen Tam; Kim, Chang-Duk; Khetre, Sanjay M.; Tamboli, Mohaseen S.; Bamane, Sambhaji R. VNBN Mahavidyalaya, Dept Chem, Shirala 415408, Maharashtra, India; Ctr Mat Elect Technol, Mat Renewable Energy & Sensor Div, Panchawati Off Pahsan Rd, Pune 411008, Maharashtra, India; King Saud Univ, Coll Sci, Dept Chem, Riyadh 11451, Saudi Arabia; Yeungnam Univ, Sch Chem Engn, 280 Daehak Ro, Gyongsan 38541, South Korea; Kyungpook Natl Univ, Dept Phys, 80 Daehakro, Daegu 41566, South Korea; Dahiwadi Coll, Dept Chem, Nanomat Res Lab, Dahiwadi 415508, Maharashtra, India; Sushila Shankarrao Gadhave Mahavidyalaya, Dept Chem, Khandala 412802, Maharashtra, India Nguyen, Anh Tuan/GXF-6089-2022; Shaikh, Shoyebmohamad/ABC-6005-2020; Khetre, S/AAF-6943-2020 57221917673; 15822047300; 57193343943; 56386846700; 57223215588; 25958384000; 57200982445; 36069381200; 6506784566; 14053593800 sandip.deshmukh555@gmail.com;sudhir1305@gmail.com;santosh87babar@gmail.com;shoyeb.chemist@gmail.com;asiyashaikh2020@gmail.com;tamnguyentn@ynu.ac.kr;duks@knu.ac.kr;sanjaykhetre@gmail.com;tamboli.mohseen@gmail.com;sambhajibamane@yahoo.com; METALS METALS-BASEL 2075-4701 11 11 SCIE MATERIALS SCIENCE, MULTIDISCIPLINARY;METALLURGY & METALLURGICAL ENGINEERING 2021 2.695 31.0 0.44 2025-07-30 4 6 TiO2-ZnO; urea; nanocomposite; combustion; photocatalysis IN-SITU SYNTHESIS; HETEROSTRUCTURES; NANOPARTICLES; DEGRADATION; FABRICATION; PARTICLES; FILMS Combustion; Nanocomposite; Photocatalysis; TiO<sub>2</sub>-ZnO; Urea English 2021 2021-11 10.3390/met11111787 바로가기 바로가기 바로가기 바로가기
Article Global regulator DksA modulates virulence of Acinetobacter baumannii DksA with (p)ppGpp regulates a wide range of gene transcriptions during the stringent response. The aim of this study was to identify a DksA ortholog in Acinetobacter baumannii and clarify the roles of DksA in bacterial physiology and virulence. The increment dksA mutant and its complemented strains were constructed using A. baumannii ATCC 17978. The AlS₀₂₄₈ in A. baumannii ATCC 17978 was identified to dksA using sequence homology, protein structure prediction, and gene expression patterns under different culture conditions. The increment dksA mutant strain showed a filamentous morphology compared with the wild-type (WT) strain. Bacterial growth was decreased in the increment dksA mutant strain under static conditions. Surface motility was decreased in the increment dksA mutant strain compared with the WT strain. In contrast, biofilm formation was increased and biofilm-associated genes, such as bfmR/S and csuC/D/E, were upregulated in the increment dksA mutant strain. The increment dksA mutant strain produced less autoinducers than the WT strain. The expression of abaI and abaR was significantly decreased in the increment dksA mutant strain. Furthermore, the increment dksA mutant strain showed less bacterial burden and milder histopathological changes in the lungs of mice than the WT strain. Mice survival was also significantly different between the increment dksA mutant and WT strains. Conclusively, DksA is directly or indirectly involved in regulating a wide range of genes associated with bacterial physiology and virulence, which contributes to the pathogenesis of A. baumannii. Thus, DksA is a potential anti-virulence target for A. baumannii infection. Kim, Nayeong; Son, Joo Hee; Kim, Kyeongmin; Kim, Hyo Jeong; Kim, Yoo Jeong; Shin, Minsang; Lee, Je Chul Kyungpook Natl Univ, Sch Med, Dept Microbiol, Daegu, South Korea 57211500281; 57201721443; 57216604095; 57221772924; 57145413200; 7401536650; 25930392000 leejc@knu.ac.kr; VIRULENCE VIRULENCE 2150-5594 2150-5608 12 1 SCIE IMMUNOLOGY;INFECTIOUS DISEASES;MICROBIOLOGY 2021 5.428 31.0 0.57 2025-07-30 9 9 Acinetobacter baumannii; DksA; virulence; quorum sensing system; biofilm formation BIOFILM FORMATION; TRANSCRIPTION INITIATION; CRITICAL COMPONENT; PPGPP; (P)PPGPP; GENES; PROMOTERS; PATHOGEN; DELETION; SURFACE Acinetobacter baumannii; biofilm formation; DksA; quorum sensing system; virulence Acinetobacter baumannii; Animals; Bacterial Proteins; Biofilms; Gene Expression Regulation, Bacterial; Mice; Virulence; chloramphenicol; kanamycin; RNA 16S; bacterial protein; Acinetobacter baumannii; animal experiment; animal model; animal tissue; Article; bacterial growth; bacterial load; bacterial strain; bacterial virulence; bacterium culture; bioassay; cell culture; colony forming unit; controlled study; female; gene deletion; gene expression; gene overexpression; genetic susceptibility; histopathology; luciferase assay; minimum bactericidal concentration; minimum inhibitory concentration; morphology; nonhuman; prediction; protein structure; quorum sensing; real time reverse transcription polymerase chain reaction; RNA isolation; sequence homology; surface motility assay; animal; biofilm; gene expression regulation; genetics; metabolism; mouse; virulence English 2021 2021-12-31 10.1080/21505594.2021.1995253 바로가기 바로가기 바로가기 바로가기
Article Identification of Novel Biomarker for Early Detection of Diabetic Nephropathy Diabetic nephropathy (DN) is one of the most common complications of diabetes mellitus. After development of DN, patients will progress to end-stage renal disease, which is associated with high morbidity and mortality. Here, we developed early-stage diagnostic biomarkers to detect DN as a strategy for DN intervention. For the DN model, Zucker diabetic fatty rats were used for DN phenotyping. The results revealed that DN rats showed significantly increased blood glucose, blood urea nitrogen (BUN), and serum creatinine levels, accompanied by severe kidney injury, fibrosis and microstructural changes. In addition, DN rats showed significantly increased urinary excretion of kidney injury molecule-1 (KIM-1) and neutrophil gelatinase-associated lipocalin (NGAL). Transcriptome analysis revealed that new DN biomarkers, such as complementary component 4b (C4b), complementary factor D (CFD), C-X-C motif chemokine receptor 6 (CXCR6), and leukemia inhibitory factor (LIF) were identified. Furthermore, they were found in the urine of patients with DN. Since these biomarkers were detected in the urine and kidney of DN rats and urine of diabetic patients, the selected markers could be used as early diagnosis biomarkers for chronic diabetic nephropathy. Kim, Kyeong-Seok; Lee, Jin-Sol; Park, Jae-Hyeon; Lee, Eun-Young; Moon, Jong-Seok; Lee, Sang-Kyu; Lee, Jong-Sil; Kim, Jung-Hwan; Kim, Hyung-Sik Sungkyunkwan Univ, Sch Pharm, Suwon 16419, South Korea; Gyeongsang Natl Univ, Inst Hlth Sci, Dept Pharmacol, Coll Med, Jinju 52727, South Korea; Soonchunhyang Univ, Cheonan Hosp, Dept Internal Med, Cheonan 31151, South Korea; Soonchunhyang Univ, Coll Med, BK21 4 Project, Cheonan 31151, South Korea; Soonchunhyang Univ, Inst Tissue Regenerat, Coll Med, Cheonan 31151, South Korea; Soonchunhyang Univ, Soonchunhyang Inst Medibio Sci, Dept Integrated Biomed Sci, Cheonan 31151, South Korea; Kyungpook Natl Univ, Coll Pharm, BK21 Plus KNU Multiom Based Creat Drug Res Team, Daegu 41566, South Korea; Gyeongsang Natl Univ Hosp, Coll Med, Inst Hlth Sci, Dept Pathol, Jinju 52727, South Korea; Gyeongsang Natl Univ, Dept Convergence Med Sci, Jinju 52727, South Korea Lee, Jin-Sol/ABI-6950-2020; Kim, Jinwoong/G-6289-2013; Lee, Eun/Q-6592-2019; Kim, Jinsoo/G-6348-2012 57100249700; 57821679000; 57208078540; 57203206532; 56501155900; 57209046767; 26650571400; 57203325580; 57344052900 caion123@nate.com;jinsol3361@skku.edu;sky3640@skku.edu;eylee@sch.ac.kr;jongseok81@sch.ac.kr;sangkyu@knu.ac.kr;jongsil25@gnu.ac.kr;junghwan.kim@gnu.ac.kr;hkims@skku.edu; BIOMEDICINES BIOMEDICINES 2227-9059 9 5 SCIE BIOCHEMISTRY & MOLECULAR BIOLOGY;MEDICINE, RESEARCH & EXPERIMENTAL;PHARMACOLOGY & PHARMACY 2021 4.757 31.0 1.95 2025-07-30 28 30 RNA-sequencing; biomarker; urine; CFD; CXCR6; C4b; LIF; diabetic nephropathy TRANSMEMBRANE CXC-CHEMOKINE; LEUKEMIA INHIBITORY FACTOR; STAGE RENAL-DISEASE; VASCULAR COMPLICATIONS; MOLECULAR BIOMARKERS; KIDNEY-DISEASE; COMPLEMENT; PROTEIN; EXPRESSION; EPIDEMIOLOGY Biomarker; C4b; CFD; CXCR6; Diabetic nephropathy; LIF; RNA-sequencing; Urine English 2021 2021-05 10.3390/biomedicines9050457 바로가기 바로가기 바로가기 바로가기
Article ppGpp signaling plays a critical role in virulence of Acinetobacter baumannii Acinetobacter baumannii, a major nosocomial pathogen, survives in diverse hospital environments, and its multidrug resistance is a major concern. The ppGpp-dependent stringent response mediates the reprogramming of genes with diverse functions in several bacteria. We investigated whether ppGpp is involved in A. baumannii's pathogenesis by examining biofilm formation, surface motility, adhesion, invasion, and mouse infection studies. Transcriptome analysis of early stationary phase cultures revealed 498 differentially-expressed genes (>= 2-fold change) in a ppGpp-deficient A. baumannii strain; 220 and 278 genes were up and downregulated, respectively. Csu operon expression, important in pilus biosynthesis during early biofilm formation, was significantly reduced in the ppGpp-deficient strain. Our findings suggest that ppGpp signaling influences A. baumannii biofilm formation, surface motility, adherence, and virulence. We showed the association between ppGpp and pathogenicity in A. baumannii for the first time; ppGpp may be a novel antivirulence target in A. baumannii. Kim, Kyeongmin; Islam, Maidul; Jung, Hye-won; Lim, Daejin; Kim, Kwangsoo; Lee, Sung-Gwon; Park, Chungoo; Lee, Je Chul; Shin, Minsang Kyungpook Natl Univ, Sch Med, Dept Microbiol, Daegu, South Korea; Chonnam Natl Univ, Dept Microbiol, Med Sch, Gwangju, South Korea; Chonnam Natl Univ, Sch Biol Sci & Technol, Gwangju, South Korea ; Islam, Md. Maidul/AAX-1696-2021 57216604095; 57216605059; 57216604654; 55634007200; 59334849100; 57194872606; 56060870500; 25930392000; 7401536650 shinms@knu.ac.kr; VIRULENCE VIRULENCE 2150-5594 2150-5608 12 1 SCIE IMMUNOLOGY;INFECTIOUS DISEASES;MICROBIOLOGY 2021 5.428 31.0 0.82 2025-07-30 13 13 Acinetobacter baumannii; ppGpp; transcriptome; biofilm; virulence C-DI-GMP; BIOFILM FORMATION; ESCHERICHIA-COLI; ABIOTIC SURFACES; (P)PPGPP; EXPRESSION; STRAIN; GENE; RELA; CONTRIBUTES Acinetobacter baumannii; biofilm; ppGpp; transcriptome; virulence Acinetobacter baumannii; Animals; Biofilms; Fimbriae, Bacterial; Gene Expression Regulation, Bacterial; Guanosine Tetraphosphate; Mice; Operon; Transcriptome; Virulence; cyclophosphamide; finasteride; long untranslated RNA; RNA 16S; tetracycline; transcriptome; guanosine 3' diphosphate 5' diphosphate; Acinetobacter baumannii; animal experiment; animal model; animal tissue; Article; bacterial gene; bacterial load; bacterial virulence; bacterium culture; biofilm; biosynthesis; brain ischemia; cell invasion; cell invasion assay; colony forming unit; confocal microscopy; controlled study; down regulation; electroporation; gene expression; gene sequence; genetic transcription; genetic transfection; methicillin resistant Staphylococcus aureus infection; minimum inhibitory concentration; mouse; multidrug resistance; nonhuman; operon; pathogenicity; phagocytosis; quality control; reverse transcription polymerase chain reaction; RNA sequence; signal transduction; upregulation; animal; fimbria; gene expression regulation; genetics; metabolism; virulence English 2021 2021-01-01 10.1080/21505594.2021.1961660 바로가기 바로가기 바로가기 바로가기
Article Removal of organochlorine insecticide endosulfan in water and soil by Fenton reaction with ascorbic acid and various iron resources An assortment of Fenton (or Fenton-like) reaction treatment systems using various iron resources such as ferrous sulfate, ferric nitrate, commercial zerovalent iron (mZVI), or self-made ZVI (Fe-nanowire) were evaluated to effectively remove alpha- and beta-isomers of endosulfan (ED) from contaminated water and soil. Ascorbic acid (AA) was added as a chelation reagent to maintain the aqueous reaction of soluble iron. In the aqueous experiment, a combined treatment of 1% mZVI, 0.01 M AA, and 0.1 M H2O2 was determined to be the most effective method, showing 98-100% of ED removal within 24 h. The mZVI/AA/H2O2 treatment method was finally applied to ED-contaminated soil samples, and the application removed significant ED residues from both soil slurries (65-73%) and immobile soils containing small amount of moisture (64-66.2%). Overall results showed that the mZVI/AA/H2O2 treatment can be utilized as a potential technique to remediate both water and soil contaminated with ED. Hwang, Jeong-In; Kim, Jang-Eok Univ Arkansas, Dept Crop Soil & Environm Sci, Fayetteville, AR 72701 USA; Kyungpook Natl Univ, Coll Agr & Life Sci, Sch Appl Biosci, Daegu 41566, South Korea 55620449700; 7601387161 jekim@knu.ac.kr; ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH ENVIRON SCI POLLUT R 0944-1344 1614-7499 28 22 SCIE ENVIRONMENTAL SCIENCES 2021 5.19 31.0 0.46 2025-07-30 8 10 Ascorbic acid; Endosulfan; Fenton reaction; Remediation; Zerovalent iron Ascorbic acid; Endosulfan; Fenton reaction; Remediation; Zerovalent iron Ascorbic Acid; Endosulfan; Hydrogen Peroxide; Insecticides; Iron; Soil; Soil Pollutants; Water; ascorbic acid; endosulfan; hydrogen peroxide; insecticide; iron; water; ascorbic acid; chemical reaction; detection method; endosulfan; endosymbiont; organochlorine; organochlorine pesticide; pollutant removal; water treatment; soil; soil pollutant English 2021 2021-06 10.1007/s11356-021-12439-2 바로가기 바로가기 바로가기 바로가기
Article Serum-Derived Neuronal Exosomal microRNAs as Stress-Related Biomarkers in an Atopic Dermatitis Model Chronic allergic inflammatory skin disease-atopic dermatitis (AD)-is characterized by eczema, pruritus, xeroderma, and lichenification. Psychological stress is one cause of this disease; however, psychological stress will also result from the presence of AD symptoms. Previous studies have shown that psychological stress triggers neuroinflammation in the brain, where microRNAs (miRNAs) in the neuronal exosomes (nEVs) were analyzed to identify the composition of the miRNAs in the nEVs and how they were altered by AD. In this study, the AD model was induced by treatment with 2,4-dinitrochlorobenzene (DNCB). The expression patterns of neuroinflammation markers, such as brain-derived neurotrophic factor, cyclooxygenase-2, and glial fibrillary acidic protein, were subsequently evaluated over time. Among these groups, there was a significant difference in DNCB 14 days expression compared with the control; therefore, nEVs were isolated from serum and next-generation sequencing was performed. The results demonstrate that 9 miRNAs were upregulated and 16 were downregulated in the DNCB 14 days compared with the control. Previous studies have shown that some of these miRNAs are associated with stress and stress-induced depression, which suggests that the miRNAs in nEVs may also be stress-related biomarkers. Sung, Minkyoung; Sung, Soo-Eun; Kang, Kyung-Ku; Choi, Joo-Hee; Lee, Sijoon; Kim, KilSoo; Lim, Ju-Hyeon; Lee, Gun Woo; Rim, Hyo-Deog; Won, Seunghee; Kim, Byung-Soo; Kim, Kyungmin; Jang, Seoyoung; Kwak, Sang Gyu; Woo, Jungmin; Seo, Min-Soo Daegu Gyeongbuk Med Innovat Fdn DGMIF, Lab Anim Ctr, Daegu 41061, South Korea; Kyungpook Natl Univ, Sch Med, Dept Psychiat, Daegu 41944, South Korea; Kyungpook Natl Univ, Coll Vet Med, 80 Daehakro, Daegu 41566, South Korea; Osong Med Innovat Fdn, New Drug Dev Ctr, Cheongju 28160, South Korea; Yeungnam Univ, Dept Orthoped Surg, Med Ctr, Coll Med, 170 Hyonchung Ro, Daegu 42415, South Korea; Catholic Univ Daegu, Sch Med, Dept Med Stat, Daegu 42472, South Korea ; Lee, Sijoon/LIC-1291-2024; Kwak, Sang Gyu/AAG-4341-2021 57256838000; 56051194000; 57215079376; 55882556800; 57219164019; 35272034300; 57218821150; 55599978600; 15768078500; 35278955600; 57214661242; 57201480192; 57258167000; 56645812600; 56241307600; 35254332100 sgkwak@cu.ac.kr;woojm3@hanmail.net;msseo@dgmif.re.kr; BIOMEDICINES BIOMEDICINES 2227-9059 9 12 SCIE BIOCHEMISTRY & MOLECULAR BIOLOGY;MEDICINE, RESEARCH & EXPERIMENTAL;PHARMACOLOGY & PHARMACY 2021 4.757 31.0 0.22 2025-07-30 4 3 atopic dermatitis; stress; exosomes; miRNA; biomarkers HPA AXIS; BRAIN; NEUROINFLAMMATION; RESILIENCE; MICROGLIA; RESPONSES; SEX Atopic dermatitis; Biomarkers; Exosomes; MiRNA; Stress English 2021 2021-12 10.3390/biomedicines9121764 바로가기 바로가기 바로가기 바로가기
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Affiliation 저자들의 소속 기관 정보입니다. 대학, 연구소, 기업 등 저자가 소속된 기관명이 표시됩니다.
ResearcherID (WoS) Web of Science의 고유 연구자 식별번호입니다. 동명이인을 구분하고 연구자의 업적을 정확하게 추적할 수 있습니다.
AuthorsID (SCOPUS) SCOPUS의 고유 저자 식별번호입니다. 연구자의 모든 출판물을 추적하고 관리하는 데 사용됩니다.
Journal 논문이 게재된 학술지의 정식 명칭입니다.
JCR Abbreviation Journal Citation Reports에서 사용하는 저널의 공식 약어입니다. 저널을 간략하게 표기할 때 사용됩니다.
ISSN International Standard Serial Number. 국제표준연속간행물번호로, 인쇄본 저널에 부여되는 고유 식별번호입니다.
eISSN Electronic ISSN. 전자 버전 저널에 부여되는 고유 식별번호입니다.
Volume 저널의 권(Volume) 번호입니다. 보통 연도별로 하나의 권이 부여됩니다.
Issue 저널의 호(Issue) 번호입니다. 한 권 내에서 여러 호로 나누어 출판되는 경우가 많습니다.
WoS Edition Web of Science의 에디션입니다. SCIE(Science Citation Index Expanded), SSCI(Social Sciences Citation Index), AHCI(Arts & Humanities Citation Index) 등으로 구분됩니다.
WoS Category Web of Science의 주제 분류 카테고리입니다. 저널과 논문이 속한 학문 분야를 나타냅니다.
JCR Year 해당 저널의 JCR(Journal Citation Reports) 지표가 산출된 연도입니다.
IF (Impact Factor) 저널 영향력 지수. 최근 2년간 발표된 논문이 해당 연도에 평균적으로 인용된 횟수를 나타냅니다. 저널의 학술적 영향력을 나타내는 대표적인 지표입니다.
JCR (%) 해당 카테고리에서 저널이 위치하는 상위 백분율입니다. 값이 낮을수록 우수한 저널임을 의미합니다 (예: 5%는 상위 5%를 의미).
FWCI Field-Weighted Citation Impact. 분야별 가중 인용 영향력 지수입니다. 논문이 받은 인용을 동일 분야, 동일 연도, 동일 문헌 유형의 평균과 비교한 값입니다. 1.0이 평균이며, 1.0보다 높으면 평균 이상의 인용을 받았음을 의미합니다.
FWCI UpdateDate FWCI 값이 마지막으로 업데이트된 날짜입니다. FWCI는 인용이 누적됨에 따라 주기적으로 업데이트됩니다.
WOS Citation Web of Science에서 집계된 해당 논문의 총 인용 횟수입니다.
SCOPUS Citation SCOPUS에서 집계된 해당 논문의 총 인용 횟수입니다.
Keywords (WoS) 저자가 논문에서 직접 지정한 키워드입니다. Web of Science에 등록된 저자 키워드 목록입니다.
KeywordsPlus (WoS) Web of Science에서 자동으로 추출한 추가 키워드입니다. 논문의 참고문헌 제목에서 자주 등장하는 단어들로 생성됩니다.
Keywords (SCOPUS) 저자가 논문에서 직접 지정한 키워드입니다. SCOPUS에 등록된 저자 키워드 목록입니다.
KeywordsPlus (SCOPUS) SCOPUS에서 자동으로 추출하거나 추가한 색인 키워드입니다.
Language 논문이 작성된 언어입니다. 대부분 English이며, 그 외 다양한 언어로 작성된 논문이 포함될 수 있습니다.
Publication Year 논문이 출판된 연도입니다.
Publication Date 논문의 정확한 출판 날짜입니다 (년-월-일 형식).
DOI Digital Object Identifier. 디지털 객체 식별자로, 논문을 고유하게 식별하는 영구적인 식별번호입니다. 이를 통해 논문의 온라인 위치를 찾을 수 있습니다.