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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Article | Characteristics of pediatric rhabdomyolysis and the associated risk factors for acute kidney injury: a retrospective multicenter study in Korea | Background: The clinical features of pediatric rhabdomyolysis differ from those of the adults with rhabdomyolysis; however, multicenter studies are lacking. This study aimed to investigate the characteristics of pediatric rhabdomyolysis and reveal the risk factors for acute kidney injury (AKI) in such cases. Methods: This retrospective study analyzed the medical records of children and adolescents diagnosed with rhabdomyolysis at 23 hospitals in South Korea between January 2007 and December 2016. Results: Among 880 patients, those aged 3 to 5 years old composed the largest subgroup (19.4%), and all age subgroups were predominantly male. The incidence of AKI was 11.3%. Neurological disorders (53.6%) and infection (39.0%) were the most common underlying disorder and cause of rhabdomyolysis, respectively. The median age at diagnosis in the AKI subgroup was older than that in the non-AKI subgroup (12.2 years vs. 8.0 years). There were no significant differences in body mass index, myalgia, dark-colored urine, or the number of causal factors between the two AKI-status subgroups. The multivariate logistic regression model indicated that the following factors were independently associated with AKI: multiorgan failure, presence of an underlying disorder, strong positive urine occult blood, increased aspartate aminotransferase and uric acid levels, and reduced calcium levels. Conclusion: Our study revealed characteristic clinical and laboratory features of rhabdomyolysis in a Korean pediatric population and highlighted the risk factors for AKI in these cases. Our findings will contribute to a greater understanding of pediatric rhabdomyolysis and may enable early intervention against rhabdomyolysis-induced AKI. | Yoo, Sukdong; Cho, Min Hyun; Baek, Hee Sun; Song, Ji Yeon; Lee, Hye Sun; Yang, Eun Mi; Yoo, Kee Hwan; Kim, Su Jin; Shin, Jae Il; Lee, Keum Hwa; Ha, Tae-Sun; Jang, Kyung Mi; Lee, Jung Won; Kim, Kee Hyuck; Cho, Heeyeon; Lee, Mee Jeong; Suh, Jin-Soon; Han, Kyoung Hee; Hyun, Hye Sun; Ha, Il-Soo; Cheong, Hae Il; Kang, Hee Gyung; Namgoong, Mee Kyung; Cho, Hye-Kyung; Oh, Jae-Hyuk; Lee, Sang Taek; Kim, Kyo Sun; Lee, Joo Hoon; Park, Young Seo; Kim, Seong Heon | Pusan Natl Univ, Dept Pediat, Sch Med, Busan, South Korea; Kyungpook Natl Univ, Sch Med, Dept Pediat, Daegu, South Korea; Natl Police Hosp, Dept Pediat, Seoul, South Korea; Chonnam Natl Univ Hosp, Dept Pediat, Gwangju, South Korea; Korea Univ, Dept Pediat, Coll Med, Seoul, South Korea; Inha Univ, Dept Pediat, Sch Med, Incheon, South Korea; Yonsei Univ, Dept Pediat, Coll Med, Seoul, South Korea; Chungbuk Natl Univ, Dept Pediat, Coll Med, Cheongju, South Korea; Yeungnam Univ, Dept Pediat, Coll Med, Daegu, South Korea; Ewha Womans Univ, Dept Pediat, Coll Med, Seoul, South Korea; Natl Hlth Insurance Corp Ilsan Hosp, Dept Pediat, Goyang, South Korea; Samsung Med Ctr, Dept Pediat, Seoul, South Korea; Dankook Univ, Dept Pediat, Coll Med, Cheonan, South Korea; Catholic Univ Korea, Dept Pediat, Bucheon St Marys Hosp, Bucheon, South Korea; Jeju Natl Univ, Dept Pediat, Sch Med, Jeju, South Korea; Catholic Univ Korea, Dept Pediat, St Vincents Hosp, Suwon, South Korea; Seoul Natl Univ, Dept Pediat, Coll Med, Seoul, South Korea; Hallym Univ Sacred Heart Hosp, Dept Pediat, Anyang, South Korea; Yonsei Univ, Dept Pediat, Wonju Coll Med, Wonju, South Korea; Gachon Univ, Dept Pediat, Gil Med Ctr, Incheon, South Korea; Ajou Univ, Dept Pediat, Sch Med, Suwon, South Korea; Samsung Changwon Hosp, Dept Pediat, Chang Won, South Korea; Konkuk Univ, Dept Pediat, Sch Med, Seoul, South Korea; Childrens Hosp, Asan Med Ctr, Dept Pediat, Seoul, South Korea | ; Lee, Yong Jae/GLR-4153-2022; Kim, Seong/AAD-8853-2020; Lee, Yong-Moon/ABD-9213-2021; Kim, Dong Ki/J-5389-2012; SHIN, JAE IL/J-6922-2017; Kim, Jeong/J-2748-2012; Suh, Jin-Soon/GNH-6543-2022; Lee, Hye/J-2154-2015; Lee, Seok/ABF-7548-2020 | 57022813800; 7401727726; 56689379700; 57204058871; 57387843400; 56665095200; 7202592702; 57203773231; 57964880100; 57193231590; 7203014522; 57203762745; 26028875500; 7409325956; 15724272900; 56080197500; 35222513700; 58389645900; 57204538255; 7005904938; 34567974000; 7404071546; 8605958900; 57037510300; 57246559600; 55894836400; 7409317338; 37112404100; 56701214400; 57213778393 | pedksh@gmail.com; | KIDNEY RESEARCH AND CLINICAL PRACTICE | KIDNEY RES CLIN PRAC | 2211-9132 | 2211-9140 | 40 | 4 | SCIE | UROLOGY & NEPHROLOGY | 2021 | 4.172 | 29.4 | 0.38 | 2025-07-30 | 5 | 4 | Creatine kinase; Etiology; Muscles; Renal insufficiency | CREATINE-KINASE; DIAGNOSIS; MORTALITY; SPECTRUM; OBESITY | Creatine kinase; Etiology; Muscles; Renal insufficiency | aspartate aminotransferase; calcium; creatine kinase; creatinine; lactate dehydrogenase; myoglobin; phosphorus; uric acid; acute kidney failure; adolescent; adult; Article; aspartate aminotransferase blood level; body mass; child; clinical feature; continuous renal replacement therapy; controlled study; diagnostic test accuracy study; disseminated intravascular clotting; electrolyte disturbance; female; height; hematuria; human; infant; major clinical study; male; multicenter study; multiple organ failure; muscle weakness; myalgia; occult blood; oliguria; peritoneal dialysis; preschool child; receiver operating characteristic; retrospective study; rhabdomyolysis; risk factor; school child; South Korea; urea nitrogen blood level; weight; young adult | English | 2021 | 2021-12 | 10.23876/j.krcp.21.051 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Executive Summary of the Korean Society of Nephrology 2021 Clinical Practice Guideline for Optimal Hemodialysis Treatment | The Korean Society of Nephrology (KSN) has published a clinical practice guideline (CPG) document for maintenance hemodialysis (HD). The document, 2021 Clinical Practice Guideline on Optimal HD Treatment, is based on an extensive evidence-oriented review of the benefits of preparation, initiation, and maintenance therapy for HD, with the participation of representative experts from the KSN under the methodologists' support for guideline development. It was intended to help clinicians participating in HD treatment make safer and more effective clinical decisions by providing user-friendly guidelines. We hope that this CPG will be meaningful as a recommendation in practice, but not on a regulatory rule basis, as different approaches and treatments may be used by health care providers depending on the individual patient's condition. This CPG consists of eight sections and 15 key questions. Each begins with statements that are graded by the strength of recommendations and quality of the evidence. Each statement is followed by a summary of the evidence supporting the recommendations. There is also a link to full-text documents and lists of the most important reports so that the readers can read further (most of this is available online). | Jung, Ji Yong; Yoo, Kyung Don; Kang, Eunjeong; Kang, Hee Gyung; Kim, Su Hyun; Kim, Hyoungnae; Kim, Hyo Jin; Park, Tae-Jin; Suh, Sang Heon; Jeong, Jong Cheol; Choi, Ji-Young; Hwang, Young-Hwan; Choi, Miyoung; Kim, Yae Lim; Oh, Kook-Hwan | Gachon Univ, Gil Med Ctr, Dept Internal Med, Div Nephrol,Coll Med, Incheon, South Korea; Univ Ulsan, Ulsan Univ Hosp, Dept Internal Med, Div Nephrol,Coll Med, Ulsan, South Korea; Ewha Womans Univ Seoul Hosp, Ewha Womans Coll Med, Dept Internal Med, Div Nephrol, Seoul, South Korea; Seoul Natl Univ Childrens Hosp, Dept Pediat, Div Pediat Nephrol, Seoul, South Korea; Chung Ang Univ Hosp, Dept Internal Med, Div Nephrol, Seoul, South Korea; Soonchunhyang Univ Seoul Hosp, Dept Internal Med, Div Nephrol, Seoul, South Korea; Pusan Natl Univ Hosp, Dept Internal Med, Div Nephrol, Busan, South Korea; Asan Jin Internal Med Clin, Seoul, South Korea; Chonnam Natl Univ Hosp, Dept Internal Med, Div Nephrol, Gwangju, South Korea; Seoul Natl Univ, Dept Internal Med, Div Nephrol, Bundang Hosp, Seongnam, South Korea; Kyungpook Natl Univ, Dept Internal Med, Div Nephrol, Chilgok Hosp, Daegu, South Korea; Truewords Dialysis Clin, Incheon, South Korea; Natl Evidence Based Healthcare Collaborating Agcy, Div Healthcare Technol Assessment Res, Seoul, South Korea; Korea Univ, Dept Biostat, Coll Med, Seoul, South Korea; Seoul Natl Univ Hosp, Dept Internal Med, Div Nephrol, Seoul, South Korea | ; Choi, Miyoung/HZH-8501-2023; Kim, Su Hyun/JPY-2079-2023; Yoo, Kyung/AAK-8096-2020; Oh, Kook-Hwan/MDS-5373-2025; Kim, Hyoungnae/JXN-1329-2024; Suh, Sang Heon/HPF-8024-2023 | 36183333400; 56603636300; 56577278700; 7404071546; 57196229394; 57191261788; 58366794000; 57228083300; 54789242500; 37761626800; 7501393222; 18835804300; 57129603200; 57284808100; 7402728369 | khoh@snu.ac.kr; | KIDNEY RESEARCH AND CLINICAL PRACTICE | KIDNEY RES CLIN PRAC | 2211-9132 | 2211-9140 | 40 | 4 | SCIE | UROLOGY & NEPHROLOGY | 2021 | 4.172 | 29.4 | 0.88 | 2025-07-30 | 6 | 9 | Evidence-based practice; GRADE approach; Hemodialysis units; Hospital; Practice guideline | MOLECULAR-WEIGHT HEPARIN; HIGH-FLUX HEMODIALYSIS; BLOOD-PRESSURE CONTROL; QUALITY-OF-LIFE; LEFT-VENTRICULAR HYPERTROPHY; RESIDUAL RENAL-FUNCTION; CHRONIC KIDNEY-DISEASE; UREA REDUCTION RATIO; ALL-CAUSE MORTALITY; ONLINE HEMODIAFILTRATION | Evidence-based practice; GRADE approach; Hemodialysis units; Hospital; Practice guideline | adult; article; GRADE approach; hemodialysis; human; maintenance therapy; nephrology; practice guideline | English | 2021 | 2021-12 | 10.23876/j.krcp.21.700 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Letter | Fighting COVID-19: The role of a COVID-19 Task Force Team | Park, Hayne Cho; Lee, Young-Ki; Cho, Jang-Hee; Lee, Sang-Ho; Kim, Dong Ki; Kim, Seong Nam; Yang, Chul-Woo | Hallym Univ, Dept Internal Med, Coll Med, 1 Singil Ro, Seoul 07441, South Korea; Kyungpook Natl Univ Hosp, Dept Internal Med, Daegu, South Korea; Kyung Hee Univ, Dept Internal Med, Coll Med, Seoul, South Korea; Seoul Natl Univ, Dept Internal Med, Coll Med, Seoul, South Korea; Kim Seong Nam Internal Med Clin, Seoul, South Korea; Catholic Univ Korea, Dept Internal Med, Coll Med, Seoul, South Korea | Kim, Dong Ki/J-5389-2012; Cho, Jang-hee/ABD-3534-2020 | 34771965700; 55716130600; 7403536291; 55890136000; 23479259100; 37031276200; 7407743404 | km2071@naver.com; | KIDNEY RESEARCH AND CLINICAL PRACTICE | KIDNEY RES CLIN PRAC | 2211-9132 | 2211-9140 | 40 | 3 | SCIE | UROLOGY & NEPHROLOGY | 2021 | 4.172 | 29.4 | 0.9 | 2025-07-30 | 2 | 2 | HEMODIALYSIS; TRANSMISSION | SARS-CoV-2 vaccine; burnout; coronavirus disease 2019; disease transmission; end stage renal disease; fever; government; health care personnel; hemodialysis; home quarantine; human; Korea; Letter; physician; polymerase chain reaction; practice guideline; Severe acute respiratory syndrome coronavirus 2; vaccination | English | 2021 | 2021-09 | 10.23876/j.krcp.21.162 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Histopathologic and clinicopathologic classifications of antineutrophil cytoplasmic antibody-associated glomerulonephritis: a validation study in a Korean cohort | Background: Antineutrophil cytoplasmic antibodies (ANCA)-associated glomerulonephritis (AAGN) is a common cause of rapidly progressive glomerulonephritis and requires prompt and proper immunosuppressive therapy to improve renal prognosis. This study aimed to evaluate the predictive value of two different classifications for renal outcomes in Korean AAGN patients. Methods: Ninety-two patients who were diagnosed with AAGN at two tertiary hospitals between 2004 and 2018 were retrospectively analyzed retrospectively. The histopathologic classification according to glomerular pathology and the clinicopathologic classification according to normal glomeruli ratio, degree of interstitial fibrosis/tubular atrophy, and baseline renal function were evaluated using the Cox proportional hazards model. Results: Forty-five patients (48.9%) progressed to end-stage kidney disease (ESKD) during the observation period. The mean age was 61.0 +/- 15.3 years, and most patients had myeloperoxidase-ANCA (93.5%). In the histopathologic classification, the best renal survival occurred in the focal class, whereas the sclerotic class had the worst renal survival (sclerotic class vs. focal class; adjusted hazard ratio [aHR], 5.05; 95% confidence interval [CI], 1.32-19.31; p = 0.018). The mixed class had intermediate renal outcomes (mixed class vs. focal class; aHR, 4.23; 95% CI, 1.23-14.58; p = 0.022). In the clinicopathologic classification, the high-risk group had poor renal outcomes compared with the low-risk group (aHR, 6.56; 95% CI, 1.25-34.26; p = 0.026), but renal outcomes did not differ between the low- and medium-risk groups. Conclusion: In Korean AAGN patients, histopathologic and clinicopathologic classifications had predictive value for renal outcomes, especially in the sclerotic class or the high-risk group with higher risk of progression to ESKD despite treatment. | Lim, Jeong-Hoon; Han, Man-Hoon; Kim, Yong-Jin; Jeon, Yena; Jung, Hee-Yeon; Choi, Ji-Young; Cho, Jang-Hee; Kim, Chan-Duck; Kim, Yong-Lim; Lee, Hajeong; Kim, Dong Ki; Moon, Kyung Chul; Park, Sun-Hee | Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu, South Korea; Kyungpook Natl Univ, Dept Internal Med, Chilgok Hosp, Daegu, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Pathol, Daegu, South Korea; Kyungpook Natl Univ, Dept Stat, Daegu, South Korea; Kyungpook Natl Univ Hosp, Dept Internal Med, Daegu, South Korea; Seoul Natl Univ, Dept Internal Med, Sch Med, Seoul, South Korea; Seoul Natl Univ Hosp, Dept Internal Med, Seoul, South Korea; Seoul Natl Univ, Dept Pathol, Coll Med, Seoul, South Korea | ; Lim, Jeong-Hoon/ABE-6003-2020; Kim, Dong Ki/J-5389-2012; Lee, Hyo/G-6299-2019; Kim, Yong-Lim/AGK-3172-2022; Park, Sun-Hee/LMN-0033-2024; Cho, Jang-hee/ABD-3534-2020; Kim, Yong-Jin/J-2745-2012 | 55360244300; 57194067936; 56150365500; 57209909350; 57196396467; 7501393222; 7403536291; 8558530700; 55633533600; 36554389800; 23479259100; 16025039700; 7501831741 | sh-park@knu.ac.kr; | KIDNEY RESEARCH AND CLINICAL PRACTICE | KIDNEY RES CLIN PRAC | 2211-9132 | 2211-9140 | 40 | 1 | SCIE | UROLOGY & NEPHROLOGY | 2021 | 4.172 | 29.4 | 0.76 | 2025-07-30 | 11 | 7 | Antibodies; Antineutrophil cytoplasmic; Classification; Glomerulonephritis; Kidney failure; Chronic; Pathology | ANCA-ASSOCIATED VASCULITIS; KIDNEY BIOPSY; DETERMINANTS; OUTCOMES; GN | Antibodies; Antineutrophil cytoplasmic; Chronic; Classification; Glomerulonephritis; Kidney failure; Pathology | azathioprine; cyclophosphamide; methylprednisolone; myeloperoxidase; neutrophil cytoplasmic antibody; prednisolone; proteinase activated receptor 3; rituximab; adult; ANCA-associated glomerulonephritis; Article; atrophy; blood pressure; cohort analysis; diabetes mellitus; drug megadose; end stage renal disease; estimated glomerular filtration rate; female; fibrosing alveolitis; follow up; glomerulonephritis; glomerulus; hemodialysis; histopathology; human; human tissue; hypertension; immunosuppressive treatment; kidney biopsy; kidney function; kidney transplantation; low drug dose; major clinical study; male; middle aged; pathology; peritoneal dialysis; protein creatinine ratio; retrospective study; serology; single blind procedure | English | 2021 | 2021-03 | 10.23876/j.krcp.20.184 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Hyperuricemia is a risk factor for the progression to end-stage renal disease in minimal change disease | Background: Minimal change disease (MCD) is one of the most common causes of nephrotic syndrome worldwide. Hyperuricemia increases the end-stage renal disease (ESRD) risk in glomerulonephritis. In this study, we aimed to determine the effect of high serum uric acid levels on the progression to ESRD in MCD. Methods: A total of 800 patients diagnosed with MCD by kidney biopsy were retrospectively analyzed. We determined the relationship of hyperuricemia with the progression to ESRD in MCD using the Cox proportional hazard model and Kaplan-Meier survival analysis. The primary outcome was defined as the initiation of dialysis or kidney transplantation. Results: A total of 42 patients (5.3%) progressed to ESRD during the follow-up period. In the restricted cubic spline curve, serum uric acid levels exhibited a positive correlation with ESRD progression in patients with MCD. In the fully adjusted model, the risk of MCD progression increased by 29% for every 1 mg/dL increase in the baseline serum uric acid level (hazard ratio [HR], 1.29; 95% confidence interval [CI], 1.09-1.54; p = 0.004). Falling into the high uric acid group (serum uric acid level > 7 mg/dL in men and > 6 mg/ dL in women) was also a risk factor for progression of MCD to ESRD (HR, 3.40; 95% CI, 1.59-7.31; p < 0.001). Conclusion: Our study shows that hyperuricemia is an independent risk factor for the progression to ESRD in patients with MCD. | Song, Su Hyun; Oh, Tae Ryom; Choi, Hong Sang; Kim, Chang Seong; Ryu, Dong Ryeol; Kim, Sung Gyun; Park, Sun-Hee; Ma, Seong Kwon; Kim, Soo Wan; Bae, Eun Hui | Chonnam Natl Univ, Dept Internal Med, Med Sch, 42 Jebong Ro, Gwangju 61469, South Korea; Ewha Womans Univ, Dept Internal Med, Coll Med, Seoul, South Korea; Hallym Univ, Dept Internal Med, Div Nephrol, Sacred Heart Hosp, Anyang, South Korea; Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu, South Korea | Kim, Soo-Yeon/ADR-9663-2022; Kim, Nan/T-8627-2019; Park, Sun-Hee/LMN-0033-2024 | 57208153154; 57104451500; 37057121100; 55938725900; 56669926200; 34770030300; 7501831741; 7403725280; 56108124300; 56463618300 | baedak76@gmail.com; | KIDNEY RESEARCH AND CLINICAL PRACTICE | KIDNEY RES CLIN PRAC | 2211-9132 | 2211-9140 | 40 | 3 | SCIE | UROLOGY & NEPHROLOGY | 2021 | 4.172 | 29.4 | 1.01 | 2025-07-30 | 8 | 10 | Chronic kidney disease; End-stage renal disease; Hyperuricemia; Minimal change disease | SERUM URIC-ACID; ACUTE KIDNEY INJURY; NEPHROTIC SYNDROME; HYPERTENSION; NEPHROPATHY; CELLS | Chronic kidney disease; End-stage renal disease; Hyperuricemia; Minimal change disease | albumin; cholesterol; hemoglobin; uric acid; adult; Article; body mass; chronic kidney failure; controlled study; creatinine blood level; diabetes mellitus; dialysis; diastolic blood pressure; disease exacerbation; end stage renal disease; estimated glomerular filtration rate; female; follow up; glomerulonephritis; human; hypertension; hyperuricemia; kidney biopsy; kidney disease; kidney transplantation; major clinical study; male; minimal change disease; prevalence; propensity score; protein blood level; protein creatinine ratio; retrospective study; risk factor; sensitivity analysis; smoking; survival analysis; systolic blood pressure; urea nitrogen blood level | English | 2021 | 2021-09 | 10.23876/j.krcp.20.220 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Metabolic risks in living kidney donors in South Korea | v Background: Considering the growing prevalence of Western lifestyles and related chronic diseases occurring in South Korea, this study aimed to explore the progression of metabolic risk factors in living kidney donors. Methods: This study enrolled living kidney donors from seven hospitals from 1982 to 2016. The controls were individuals that voluntarily received health check-ups from 1995 to 2016 that were matched with donors according to age, sex, diabetes status, baseline estimated glomerular filtration rate, and date of the medical record. Data on hyperuricemia, hypertension, hypercholesterolemia, and overweight/obesity were collected to determine metabolic risks. Logistic regressions with interaction terms between the medical record date and donor status were used to compare the trends in metabolic risks over time in the two groups. Results: A total of 2,018 living kidney donors and matched non-donors were included. The median age was 44.0 years and 54.0% were women. The living kidney donors showed a lower absolute prevalence for all metabolic risk factors, except for those that were overweight/obese, than the non-donors. The proportion of subjects that were overweight/obese was consistently higher over time in the donor group. The changes over time in the prevalence of each metabolic risk were not significantly different between groups, except for a lower prevalence of metabolic risk factors >= 3 in donors. Conclusion: Over time, metabolic risks in living kidney donors are generally the same as in non-donors, except for a lower prevalence of metabolic risk factors >= 3 in donors. | Kang, Eunjeong; Park, Jina; Kim, Hyo Jeong; Park, Sehoon; Park, Minsu; Kim, Yaerim; Kim, Kwangsoo; Park, Sang Min; Chae, Dong-Wan; Chin, Ho Jun; Lee, Jung Pyo; Lee, Sik; Kim, Soo Wan; Cho, Jang-Hee; Han, Miyeun; Kim, Yong Chul; Kim, Yon Su; Choi, Insun; Lee, Hajeong | Ewha Womans Univ, Ewha Womans Univ Seoul Hosp, Dept Internal Med, Coll Med, Seoul, South Korea; Korea Univ, Dept Biostat, Coll Med, Seoul, South Korea; Natl Evidence Based Healthcare Collaborating Agcy, Div Healthcare Technol Assessment Res, Seoul, South Korea; Seoul Natl Univ, Dept Biomed Sci, Coll Med, Seoul, South Korea; Keimyung Univ, Dept Stat, Daegu, South Korea; Keimyung Univ, Dept Internal Med, Dongsan Hosp, Daegu, South Korea; Seoul Natl Univ Hosp, Transdisciplinary Dept Med & Adv Technol, Seoul, South Korea; Seoul Natl Univ Hosp, Dept Family Med, Seoul, South Korea; Seoul Natl Univ, Dept Internal Med, Bundang Hosp, Seongnam, South Korea; SMG SNU Boramae Med Ctr, Dept Internal Med, Seoul, South Korea; Chonbuk Natl Univ Hosp, Dept Internal Med, Jeonju, South Korea; Chonnam Natl Univ Hosp, Dept Internal Med, Gwangju, South Korea; Kyungpook Natl Univ, Dept Internal Med, Daegu, South Korea; Hallym Univ, Dept Internal Med, Hangang Sacred Heart Hosp, Seoul, South Korea; Seoul Natl Univ Hosp, Dept Internal Med, 101 Daehak Ro, Seoul 03080, South Korea | Lee, Hyo/G-6299-2019; Han, Miyeun/AAE-7569-2022; Kim, Sang/J-5399-2012; Kim, Nan/T-8627-2019; Kim, Dae/AAJ-7518-2021; Cho, Jang-hee/ABD-3534-2020; Chin, Ho/J-5678-2012; Park, Sang/V-9194-2019; Kim, Yong/L-8653-2019; Chae, Dong-Wan/J-5681-2012 | 56577278700; 57221837324; 57476930200; 57210030734; 57201652582; 57202790600; 57210575084; 58509146900; 23471686900; 23495522400; 56028990400; 57192521521; 56108124300; 7403536291; 55899659500; 57026583000; 7410205767; 57311279600; 36554389800 | mdhjlee@gmail.com; | KIDNEY RESEARCH AND CLINICAL PRACTICE | KIDNEY RES CLIN PRAC | 2211-9132 | 2211-9140 | 40 | 4 | SCIE | UROLOGY & NEPHROLOGY | 2021 | 4.172 | 29.4 | 0.63 | 2025-07-30 | 6 | 7 | Hypercholesterolemia; Hyperuricemia; Kidney transplantation; Living donors; Risk factors | SERUM URIC-ACID; NATIONAL-HEALTH; PREVALENCE; ADULTS; TRANSPLANTATION; HYPERTENSION; MANAGEMENT; MORTALITY; DONATION | adult; Article; chronic disease; controlled study; diabetes mellitus; estimated glomerular filtration rate; female; human; hypercholesterolemia; hypertension; hyperuricemia; kidney donor; living donor; major clinical study; male; metabolic syndrome X; middle aged; multicenter study; nephrectomy; obesity; prevalence; retrospective study; risk factor; sensitivity analysis; systolic blood pressure; urea nitrogen blood level | English | 2021 | 2021-12 | 10.23876/j.krcp.20.271 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Physicochemical characterization of encapsulated sulfides in zeolite 4A | Sulfides encapsulated in zeolite 4A have been known to be stabilized by protection of the inorganic framework in spite of the possibility that they could be decomposed and eventually released into environment. This study focused on their release properties along with identification of the chemical species and location. At an optimized treatment condition, zeolite 4A encapsulated sulfides to be the total sulfur content up to a weight % of 10.61. Major encapsulated sulfides were identified to be S-6(2-) in alpha-cage and S-3(center dot-) in beta-cage, respectively. Extraction with deionized water revealed that 77% of the encapsulated sulfides was rapidly released within 3 days while the rest was gradually and completely released within 3 weeks. It was suggested in zeolite 4A that S-6(2) in a-cage was released rapidly whereas S-3(center dot-) in beta-cage slowly. This release behavior of encapsulated sulfides provides a new strategy to explore their potentials for advanced applications. | Jang, Jeong-Hun; Kim, Junhyung; Seo, Jae-Deok; Hwang, Seung-Han; Park, Man | Kyungpook Natl Univ, Sch Appl Biosci, Soil Sci Lab, 80 Daehakro, Daegu 41566, South Korea | 57198251792; 56178833600; 57216441278; 57254311800; 36871192900 | manpark@knu.ac.kr; | JOURNAL OF SOLID STATE CHEMISTRY | J SOLID STATE CHEM | 0022-4596 | 1095-726X | 304 | SCIE | CHEMISTRY, INORGANIC & NUCLEAR;CHEMISTRY, PHYSICAL | 2021 | 3.656 | 29.4 | 0.08 | 2025-07-30 | 2 | 2 | Zeolite; Encapsulation; Release behavior; Sulfide; Sulfur cluster | SULFUR; ADSORPTION; EFFICIENCY; REMOVAL; RAMAN | Encapsulation; Release behavior; Sulfide; Sulfur cluster; Zeolite | Deionized water; Zeolites; Advanced applications; Chemical species; Physico-chemical characterization; Release behaviors; Release property; Total sulfur; Treatment conditions; Zeolite 4A; Sulfur compounds | English | 2021 | 2021-12 | 10.1016/j.jssc.2021.122539 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Self-condensation route to Al13-magadiite complex for arsenate removal | Al polycations like epsilon-Al-13 Keggin cluster [AlO4Al12(OH)(24)(H2O)(12)(7+)] (referred to as Al-13) are promising for removal of arsenate from drinking-water. However, their practical applications are rather limited because mainly of difficulty in post-retrieving and of acute biotoxicity. Although complexation with clay minerals has been suggested to overcome these limitations, it led typically to appreciable inactivation of exposed OH groups. This study has attempted to fabricate Al-13-complexed magadiite by simple cation exchange reaction without any further treatments. Any noticeable back-release of Al-13 was not observed to confirm stable complexation between Al-13 and magadiite. Al-13-complexed magadiite exhibited maximum adsorption capacity of similar to 30.3 mu mol g(-1) for arsenate predominantly by chemisorption. Furthermore, it was revealed that Al-13-complexed magadiite removed arsenate completely in a concentration level below 1 mg L-1 (below detection limit of 0.52 mu g L-1). This study provides a new tailor-making approach to the adsorbents for complete removal of low-level aqueous arsenate. | Kim, Junhyung; Atulba, Sarah Louise S.; Jang, Jeong-Hun; Kang, Yun-Ju; Park, Man | Kyungpook Natl Univ, Sch Appl Biosci, Soil Sci Lab, 80 Daehakro, Daegu 41566, South Korea; Kyungpook Natl Univ, Dept Appl Biosci, 80 Daehakro, Daegu 41566, South Korea | 56178833600; 56001070600; 57198251792; 57216430845; 36871192900 | manpark@knu.ac.kr; | JOURNAL OF SOLID STATE CHEMISTRY | J SOLID STATE CHEM | 0022-4596 | 1095-726X | 300 | SCIE | CHEMISTRY, INORGANIC & NUCLEAR;CHEMISTRY, PHYSICAL | 2021 | 3.656 | 29.4 | 0.24 | 2025-07-30 | 4 | 4 | Arsenic; Al-13; Adsorbent; Layered silicate; Grafting; Cation exchange | MAGADIITE | Adsorbent; Al<sub>13</sub>; Arsenic; Cation exchange; Grafting; Layered silicate | Potable water; Adsorption capacities; Arsenate removal; Cation exchange reactions; Concentration levels; Detection limits; Further treatments; Polycations; Self-condensation; Aluminum compounds | English | 2021 | 2021-08 | 10.1016/j.jssc.2021.122225 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Trends in epidemiologic characteristics of end-stage renal disease from 2019 Korean Renal Data System (KORDS) | Background: The Korean Society of Nephrology (KSN) has maintained a nationwide end-stage renal disease (ESRD) registry data from Korean Renal Data System (KORDS) since 1985, as the representative registry of ESRD patients in Korea. This review is aimed to update the status of domestic ESRD and to provide evidence on the direction of dialysis therapy. Methods: The KORDS Committee of KSN has collected data on dialysis centers and patients through an online registry program, and the data from 1986 to 2019 were analyzed. Results: The incidence and prevalence of ESRD patients in Korea are increasing. The ESRD population numbered more than 100,000 in 2019, doubling during the 10 years since 2010. The proportion of diabetes mellitus as a major cause of ESRD seems to have reached a plateau. The increasing number of elderly dialysis patients is a constant trend, with more than half for the proportion of patients older than 65 years old in 2019. All-cause mortality decreased for the last approximately 20 years, regardless of sex, age, and cause of ESRD. The 5-year patient survival rate in both hemodialysis and peritoneal dialysis increased from 2001 to 2013. Since 2013, the patient survival rates in peritoneal dialysis were similar to those in hemodialysis. Cardiovascular complications were the leading cause of death in ESRD patients. Conclusion: The incidence and prevalence of Korean ESRD patients have increased over time, although patient survival has also steadily increased. The establishment of a surveillance method to address the major cause of mortality in ESRD patients will help improve outcomes. | Hong, Yu Ah; Ban, Tae Hyun; Kang, Chae-Yeong; Hwang, Sun Deuk; Choi, Sun Ryoung; Lee, Hajeong; Jung, Hee-Yeon; Kim, Kyeongmin; Kwon, Young Eun; Kim, Su Hyun; Kim, Tae Hee; Koo, Ho-Seok; Yoon, Chang-Yun; Kim, Kiwon; Park, Jongha; Kim, Yong Kyun | Catholic Univ Korea, Coll Med, Dept Internal Med, Seoul, South Korea; Korean Soc Nephrol, Seoul, South Korea; Inha Univ, Dept Internal Med, Coll Med, Incheon, South Korea; Hallym Univ, Dept Internal Med, Dongtan Sacred Heart Hosp, Hwaseong, South Korea; Seoul Natl Univ Hosp, Dept Internal Med, Seoul, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Internal Med, Daegu, South Korea; Eulji Univ, Daejeon Eulji Med Ctr, Dept Internal Med, Daejeon, South Korea; Hanyang Univ, Myongji Hosp, Dept Internal Med, Coll Med, Goyang, South Korea; Chung Ang Univ Hosp, Dept Internal Med, Seoul, South Korea; Inje Univ, Dept Internal Med, Coll Med, Busan, South Korea; Yoons Med Clin, Dialysis Ctr, Seoul, South Korea; Seoul One Clin, Anyang, South Korea; Univ Ulsan, Ulsan Univ Hosp, Dept Internal Med, Coll Med, Ulsan, South Korea | Lee, Hyo/G-6299-2019; Kim, Su Hyun/JPY-2079-2023; Kim, TaeHee/KHT-9235-2024; choi, sun ryoung/AGZ-1893-2022; Hong, Yu/AAB-7055-2020; Jung, Hee-Yeon/AFB-8578-2022 | 55125210000; 56119751700; 58037684600; 57145681000; 36994562600; 36554389800; 57196396467; 57199438486; 57204666157; 57196229394; 57191984775; 56888361500; 59577514300; 55710561400; 54786765100; 57218459728 | jonghaparkmd@gmail.com;drkimyk@catholic.ac.kr; | KIDNEY RESEARCH AND CLINICAL PRACTICE | KIDNEY RES CLIN PRAC | 2211-9132 | 2211-9140 | 40 | 1 | SCIE | UROLOGY & NEPHROLOGY | 2021 | 4.172 | 29.4 | 10.34 | 2025-07-30 | 100 | 104 | Chronic kidney failure; Incidence; Mortality; Prevalence | Chronic kidney failure; Incidence; Mortality; Prevalence | aged; all cause mortality; Article; cardiovascular disease; cause of death; cerebrovascular accident; chronic glomerulonephritis; coronary artery disease; diabetes mellitus; end stage renal disease; female; gastrointestinal hemorrhage; heart arrest; hemodialysis; human; hypertension; incidence; kidney disease; Korea; liver failure; lung embolism; male; malnutrition; peritoneal dialysis; peritonitis; pneumonia; prevalence; questionnaire; sepsis; suicide; survival rate; tuberculosis | English | 2021 | 2021-03 | 10.23876/j.krcp.20.202 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Humoral and cellular immune response to Plasmodium vivax VIR recombinant and synthetic antigens in individuals naturally exposed to P. vivax in the Republic of Korea | Background Plasmodium vivax proteins with variant interspersed repeats (VIR) are the key proteins used by the parasite to escape from the host immune system through the creation of antigenic variations. However, few studies have been done to elucidate their role as targets of immunity. Thus, this study evaluated the naturally-acquired immune response against VIR proteins in vivax malaria-infected individuals in the Republic of Korea (ROK). Methods Seven recombinant VIR proteins and two synthetic peptides previously studied in other countries that elicited a robust immune response were used to investigate the antibody and cellular immune response in 681 P. vivax-infected people in ROK. The expression of IgM, IgG, and IgG subclasses against each VIR antigen or against PvMSP1-19 was analysed by ELISA. PvMSP1-19, known as a promising vaccine candidate of P. vivax, was used as the positive control for immune response assessment. Furthermore, the cellular immune response to VIR antigens was evaluated by in vitro proliferative assay, cellular activation assay, and cytokine detection in mononuclear cells of the P. vivax-infected population. Results IgM or IgG were detected in 52.4% of the population. Among all the VIR antigens, VIR25 elicited the highest humoral immune response in the whole population with IgG and IgM prevalence of 27.8% and 29.2%, respectively, while PvMSP1-19 elicited even higher prevalence (92%) of IgG in the population. As for the cellular immune response, VIR-C2, PvLP2, and PvMSP1-19 induced high cell activation and secretion of IL-2, IL-6, IL-10, and G-CSF in mononuclear cells from the P. vivax-infected population, comparable with results from PvMSP1-19. However, no significant proliferation response to these antigens was observed between the malaria-infected and healthy groups. Conclusion Moderate natural acquisition of antibody and cellular responses in P. vivax-infected Korean malaria patients presented here are similar to that in other countries. It is interesting that the immune response to VIR antigens is conserved among malaria parasites in different countries, considering that VIR genes are highly polymorphic. This thus warrants further studies to elucidate molecular mechanisms by which human elicit immune response to the malaria parasite VIR antigens. | Lee, Sanghyun; Choi, Young-Ki; Goo, Youn-Kyoung | Chungbuk Natl Univ, Coll Med, Dept Microbiol, Cheongju 28644, South Korea; Chungbuk Natl Univ, Med Res Inst, Cheongju 28644, South Korea; Kyungpook Natl Univ, Sch Med, Dept Parasitol & Trop Med, Daegu 41944, South Korea; Korea Dis Control & Prevent Agcy, Korea Natl Inst Hlth, Dept Precis Med, Div Bio Bigdata, Cheongju 28159, Chungbuk, South Korea | 56272461500; 7404776658; 22937863200 | choiki55@chungbuk.ac.kr;kuku1819@knu.ac.kr; | MALARIA JOURNAL | MALARIA J | 1475-2875 | 20 | 1 | SCIE | INFECTIOUS DISEASES;PARASITOLOGY;TROPICAL MEDICINE | 2021 | 3.469 | 29.5 | 0.81 | 2025-07-30 | 10 | 9 | Plasmodium vivax; Variant interspersed repeats protein; Cellular immune response; Humoral immune response | MALARIA; SURFACE; GENES; ERYTHROCYTES; SUPERFAMILY; FALCIPARUM; PROTEINS; REGIONS | Cellular immune response; Humoral immune response; Plasmodium vivax; Variant interspersed repeats protein | Adolescent; Adult; Antigens, Protozoan; Female; Humans; Immunity, Cellular; Immunity, Humoral; Interspersed Repetitive Sequences; Malaria Vaccines; Malaria, Vivax; Male; Middle Aged; Plasmodium vivax; Republic of Korea; Vaccines, Synthetic; Young Adult; granulocyte colony stimulating factor; immunoglobulin G; immunoglobulin M; interleukin 10; interleukin 2; interleukin 6; MSP1 19; recombinant protein; unclassified drug; VIR protein; virus vaccine; malaria vaccine; parasite antigen; recombinant vaccine; adult; antibody production; Article; cell activation; cellular immunity; controlled study; enzyme linked immunosorbent assay; female; gene; human; human cell; humoral immunity; immune response; in vitro study; major clinical study; malaria; male; mononuclear cell; nonhuman; Plasmodium; Plasmodium vivax; prevalence; protein analysis; protein expression; protein function; protein secretion; South Korea; vaccination; VIR gene; adolescent; immunology; interspersed repeat; middle aged; Plasmodium vivax; Plasmodium vivax malaria; young adult | English | 2021 | 2021-06-28 | 10.1186/s12936-021-03810-2 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Jazf1 acts as a regulator of insulin-producing β-cell differentiation in induced pluripotent stem cells and glucose homeostasis in mice | Genetic susceptibility of type 2 diabetes and Juxtaposed with another zinc finger protein 1 (Jazf1) has been reported; however, the precise role of Jazf1 in metabolic processes remains elusive. In this study, using Jazf1-knockout (KO)-induced pluripotent stem cells (iPSC), pancreatic beta cell line MIN6 cells, and Jazf-1 heterozygous KO (Jazf1(+/-)) mice, the effect of Jazf1 on gradual differentiation was investigated. We checked the alterations of the genes related with beta-cell specification, maturation, and insulin release against glucose treatment by the gain and loss of the Jazf1 gene in the MIN6 cells. Because undifferentiated Jazf1-KO iPSC were not significantly different from wild-type (WT) iPSC, the size and endoderm marker expression after embryoid body (EB) and teratoma formation were investigated. Compared to EB and teratomas formed with WT iPSC, the EB and teratomas from with Jazf1-KO iPSC were smaller, and in teratomas, the expression of proliferation markers was reduced. Moreover, the expression of the gene sets for beta-cell differentiation and the levels of insulin and C-peptide secreted by insulin precursor cells were notably reduced in beta-cells differentiated from Jazf1-KO iPSC compared with those differentiated from WT iPSC. A comparison of Jazf1(+/-) and WT mice showed that Jazf1(+/-) mice had lower levels of serum insulin, pancreatic insulin expression, and decreased pancreatic beta-cell size, which resulted in defects in the glucose homeostasis. These findings suggest that Jazf1 plays a pivotal role in the differentiation of beta-cells and glucose homeostasis. | Park, Si Jun; Kwon, Wookbong; Park, Song; Jeong, Jain; Kim, Dongjun; Jang, Soyoung; Kim, Si-Yong; Sung, Yonghun; Kim, Myoung Ok; Choi, Seong-Kyoon; Ryoo, Zae Young | Kyungpook Natl Univ, Sch Life Sci, Plus KNU Creat BioRes Grp BK21, Daegu 41566, South Korea; Kyungpook Natl Univ, Inst Life Sci & Biotechnol, Daegu, South Korea; DGIST, Div Biotechnol, Daegu, South Korea; DGIST, Core Prot Resources Ctr, Daegu, South Korea; DGIST, Dept Brain & Cognit Sci, Daegu, South Korea; Yale Univ, Sch Med, Dept Internal Med, Sect Digest Dis, New Haven, CT 06510 USA; Daegu Gyeongbuk Med Innovat Fdn, Lab Anim Ctr, Daegu, South Korea; Kyungpook Natl Univ, Dept Anim Sci & Biotechnol, Sangju, South Korea | RYOO, ZAEYOUNG/AAQ-1573-2020 | 54682212300; 57139843600; 57139047900; 56009456100; 57212195756; 57139360300; 57212197751; 58903739800; 8934745900; 55505432500; 16937104900 | jaewoong64@knu.ac.kr; | FEBS JOURNAL | FEBS J | 1742-464X | 1742-4658 | 288 | 14 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY | 2021 | 5.622 | 29.5 | 0.55 | 2025-07-30 | 9 | 9 | diabetes; insulin homeostasis; iPSC; Jazf1; β ‐ cell differentiation | DIABETES-MELLITUS; SECRETORY DYSFUNCTION; HEPATIC STEATOSIS; RESISTANCE; PROLIFERATION; EXPRESSION; CHALLENGES; GENERATION; VARIANTS; GENES | diabetes; insulin homeostasis; iPSC; Jazf1; β-cell differentiation | Animals; Cell Differentiation; Cells, Cultured; Co-Repressor Proteins; DNA-Binding Proteins; Female; Glucose; Homeostasis; Induced Pluripotent Stem Cells; Insulin; Insulin-Secreting Cells; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Organogenesis; C peptide; glucose; insulin; juxtaposed with another zinc finger protein 1; messenger RNA; unclassified drug; zinc finger protein; corepressor protein; DNA binding protein; glucose; insulin; JAZF1 protein, mouse; animal cell; animal experiment; animal model; animal tissue; Article; bone metabolism; cell differentiation; cell proliferation; cell proliferation assay; cell size; colony formation; controlled study; Cytomegalovirus; diabetes mellitus; embryoid body; endoderm; enzyme linked immunosorbent assay; female; food intake; gene expression; genetic association; genetic transduction; genetic transfection; genotype; glucose blood level; glucose homeostasis; glucose tolerance test; heterozygosity; immunocytochemistry; immunofluorescence; immunohistochemistry; induced pluripotent stem cell; insulin blood level; insulin release; insulin sensitivity; insulin tolerance test; knockout gene; knockout mouse; male; MIN6 cell line; mouse; neural stem cell; nonhuman; nuclear reprogramming; pancreas islet beta cell; plasmid; pluripotent stem cell; protein blood level; protein expression; protein function; rat; real time polymerase chain reaction; reverse transcription polymerase chain reaction; RNA extraction; teratoma; tissue microarray; Western blotting; animal; C57BL mouse; cell culture; cytology; homeostasis; induced pluripotent stem cell; metabolism; organogenesis; pancreas islet beta cell; physiology | English | 2021 | 2021-07 | 10.1111/febs.15751 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Multiplex PCR assay for the identification of eight Anopheles species belonging to the Hyrcanus, Barbirostris and Lindesayi groups | Background Genus Anopheles mosquitoes are the primary vectors of human malaria, which is a serious threat to public health worldwide. To reduce the spread of malaria and identify the malaria infection rates in mosquitoes, accurate species identification is needed. Malaria re-emerged in 1993 in the Republic of Korea (ROK), with numbers peaking in 2004 before decreasing to current levels. Eight Anopheles species (Anopheles sinensis, Anopheles pullus, Anopheles belenrae, Anopheles lesteri, Anopheles kleini, Anopheles sineroides, Anopheles koreicus, Anopheles lindesayi) are distributed throughout Korea. Members of the Anopheles Hyrcanus group currently cannot be identified morphologically. The other species of Anopheles can be identified morphologically, except when specimens are damaged in traps. The purpose of this study was to develop a rapid and accurate method for simultaneous molecular identification of the eight Anopheles species present in the ROK. Methods Anopheles spp. used in this study were collected near/in the demilitarized zone in ROK, where most malaria cases are reported. DNA from 165 of the Anopheles specimens was used to develop a multiplex PCR assay. The internal transcribed spacer 2 (ITS2) region of each species was sequenced and analysed for molecular identification. Results DNA from a total of 165 Anopheles specimens was identified to species using a multiplex diagnostic system. These included: 20 An. sinensis, 21 An. koreicus, 17 An. lindesayi, 25 An. kleini, 11 An. lesteri, 22 An. sineroides, 23 An. belenrae, and 26 An. pullus. Each species was clearly distinguished by electrophoresis as follows: 1,112 bp for An. sinensis; 925 bp for An. koreicus; 650 bp for An. lindesayi; 527 bp for An. kleini; 436 bp for An. lesteri; 315 bp for An. sineroides; 260 bp for An. belenrae; and, 157 bp for An. pullus. Conclusion A multiplex PCR assay was developed to identify Anopheles spp. distributed in ROK. This method can be used to accurately identify Anopheles species that are difficult to identify morphologically to determine species distributions and malaria infection rates. | Bang, Woo Jun; Kim, Heung Chul; Ryu, Jihun; Lee, Hyeon Seung; Lee, So Youn; Kim, Myung Soon; Chong, Sung Tae; Klein, Terry A.; Choi, Kwang Shik | Kyungpook Natl Univ, FOUR KNU Creat BioRes Grp BK21, Sch Life Sci, Daegu 41566, South Korea; Kyungpook Natl Univ, Res Inst Dokdo & Ulleungdo Isl, Daegu 41566, South Korea; Force Hlth Protect & Prevent, Med Dept Activity Korea, Unit 15281, 65th Med Brigade, APO, AP 96271 USA; Kyungpook Natl Univ, Res Inst Phylogenom & Evolut, Daegu 41566, South Korea | Kim, Duk Hwan/AAC-5666-2022; Lee, Seunghyun/AAS-8066-2021; Lee, Seunghwan/E-4992-2011; Ryu, Jihun/MSY-6008-2025 | 57225182172; 8847173600; 57210884178; 57225171629; 57225174719; 55789464100; 11840251100; 7202313728; 36602283400 | ksc@knu.ac.kr; | MALARIA JOURNAL | MALARIA J | 1475-2875 | 20 | 1 | SCIE | INFECTIOUS DISEASES;PARASITOLOGY;TROPICAL MEDICINE | 2021 | 3.469 | 29.5 | 1.01 | 2025-07-30 | 13 | 13 | Anopheles; Multiplex PCR assay; Malaria; Korea | REPUBLIC-OF-KOREA; PLASMODIUM-VIVAX; MALARIA VECTORS; GAMBIAE COMPLEX; DIPTERA; CULICIDAE; MEMBERS; COMPETENCE; FUNESTUS; SINENSIS | Anopheles; Korea; Malaria; Multiplex PCR assay | Animals; Anopheles; Mosquito Vectors; Multiplex Polymerase Chain Reaction; Republic of Korea; animal; Anopheles; classification; mosquito vector; multiplex polymerase chain reaction; procedures; South Korea | English | 2021 | 2021-06-28 | 10.1186/s12936-021-03808-w | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Properties of ITO films deposited on paper sheets using a low-frequency (60 Hz) DC-pulsed magnetron sputtering method | Indium tin oxide (ITO) films were deposited on paper sheets using a low-frequency (60 Hz) DC-pulsed magnetron sputtering (LF-DPMS) with a modified sputtering gun. The deposited ITO films exhibited a cubic structure with a grain size of 20.5 nm. The work function of the films was 4.94 eV, and the surface was highly hydrophobic with a contact angle of 116?. The transmittance at a wavelength of 550 nm was 86.6% and the optical bandgap was 3.33 eV. The resistivity and the sheet resistance were 8.08 ? 10-3 ?cm and 40.4 ?/?. By the end of the deposition process, the fabric structure of the paper sheet remained in good condition, and the as-deposited paper sheet did not bend due to the residual stress of ITO films. From these results, LF-DPMS is considered a damagefree deposition technique, and is rather effective for film depositions on weak substrates including papers, polymers, and fibers. | Kim, Hong Tak; Jung, Sang Kooun; Lee, Sung-Youp | Yeungnam Univ, Sch Chem Engn, Gyongsan 38541, South Korea; Kyungpook Natl Univ, Dept Phys, Daegu 41566, South Korea; Econet Korea, Gumi 39170, South Korea | 7410138212; 7403677056; 14830491400 | physylee@knu.ac.kr; | VACUUM | VACUUM | 0042-207X | 1879-2715 | 187 | SCIE | MATERIALS SCIENCE, MULTIDISCIPLINARY;PHYSICS, APPLIED | 2021 | 4.11 | 29.5 | 1.05 | 2025-07-30 | 13 | 14 | DC-Pulsed; ITO; Low-frequency; Paper; Sputtering | THIN-FILMS; PYROLYSIS | DC-Pulsed; ITO; Low-frequency; Paper; Sputtering | Contact angle; Indium compounds; Magnetron sputtering; Paper products; Tin oxides; Cubic structure; Deposition process; Deposition technique; Fabric structures; Film deposition; Indium Tin Oxide films; Low-frequency; Pulsed magnetron sputtering; Oxide films | English | 2021 | 2021-05 | 10.1016/j.vacuum.2021.110056 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Collagen type VI-α1 and 2 repress the proliferation, migration and invasion of bladder cancer cells | The bladder cancer (BCa) microenvironment comprises heterogeneous tumor cell populations, the surrounding stroma and the extracellular matrix (ECM). Collagen, the scaffold of the tumor microenvironment, regulates ECM remodeling to promote tumor infiltration, angiogenesis, invasion and migration. The present study examined how collagen type VI-alpha (COL6A) 1 and 2 function during BCa pathogenesis and progression, with the aim of facilitating the development of precision therapeutics, risk stratification and molecular diagnosis. COL6A1 and COL6A2 mRNA expression in non-muscle invasive BCa (NMIBC) and MIBC tissue samples was measured using reverse transcription-quantitative PCR. In addition, the tumor-suppressive effects of COL6A1 and COL6A2 in human BCa EJ cells (MGH-U1) were assessed. Compared with normal controls, COL6A1 and COL6A2 mRNA expression was downregulated in both NMIBC and MIBC tissue samples (P<0.05, respectively). COL6A1 and COL6A2 effectively inhibited the proliferation of human BCa EJ cells (MGH-U1) and induced cell cycle arrest at the G(1) phase. Additionally, COL6A1 and COL6A2 served roles in MAPK and AKT signaling by increasing p38 MAPK phosphorylation and decreasing AKT phosphorylation. Finally, COL6A1 and COL6A2 inhibited wound healing and invasion by suppressing the activity of matrix metalloproteinase (MMP)-2 and MMP-9. In conclusion, COL6A1 and COL6A2 may act as classical collagens by forming a physical barrier to inhibit BCa tumor growth and invasion. | Piao, Xuan-Mei; Hwang, Byungdoo; Jeong, Pildu; Byun, Young Joon; Kang, Ho Won; Seo, Sung Phil; Kim, Won Tae; Lee, Jong-Young; Ha, Yun-Sok; Lee, Young-Suk; Kim, Isaac Y.; Choi, Yung Hyun; Cha, Eun-Jong; Moon, Sung-Kwon; Yun, Seok Joong; Kim, Wun-Jae | Chungbuk Natl Univ, Coll Med, Dept Urol, Cheongju 28644, Chungcheongbuk, South Korea; Chung Ang Univ, Dept Food Sci & Technol, Anseong 456756, Gyeonggi, South Korea; Chungbuk Natl Univ Hosp, Dept Urol, Cheongju 28644, Chungcheongbuk, South Korea; Oneom Inst, Seoul 04158, South Korea; Kyungpook Natl Univ, Sch Med, Dept Urol, Daegu, South Korea; Kyungpook Natl Univ Hosp, Dept Urol, Daegu 41566, South Korea; Sungkyunkwan Univ, Sch Med, Samsung Changwon Hosp, Dept Urol, Chang Won 51353, Gyeongsangnam, South Korea; Canc Inst New Jersey, Sect Urol Oncol, New Brunswick, NJ 08903 USA; Canc Inst New Jersey, Dean & Betty Gallo Prostate Canc Ctr, New Brunswick, NJ 08903 USA; Univ Med & Dent New Jersey, New Brunswick, NJ 08903 USA; Dong Eui Univ, Coll Oriental Med, Dept Biochem, Busan 614052, South Korea; Chungbuk Natl Univ, Coll Med, Dept Biomed Engn, Cheongju, South Korea; Inst Urotech, Chungdae Ro 1, Cheongju 28644, Chungcheongbuk, South Korea | Lee, Young-suk/JCD-8336-2023; Kim, Jae-hyung/J-8504-2012; Lee, Jong-Young/M-6319-2013; Piao, Xuan-Mei/ABI-6955-2020; Kim, Kyu/E-7814-2012 | 57188653344; 7201454006; 8890123500; 57188656800; 35757703900; 56115644100; 57203514393; 57820672500; 35487226400; 27168810200; 7404143831; 57211727369; 7003760756; 7401616572; 16302421300; 8081691400 | wjkim@chungbuk.ac.kr; | INTERNATIONAL JOURNAL OF ONCOLOGY | INT J ONCOL | 1019-6439 | 1791-2423 | 59 | 1 | SCIE | ONCOLOGY | 2021 | 5.884 | 29.6 | 1.86 | 2025-07-30 | 28 | 30 | COL6A; BCa; tumor suppressor; pathogenesis; progression | INDUCED PHOSPHORYLATION; PROSTATE-CANCER; EXPRESSION; COL6A1; PROGRESSION; GUIDELINES; PROGNOSIS; CARCINOMA; COMPONENT; PATHWAY | BCa; COL6A; Pathogenesis; Progression; Tumor suppressor | Adult; Aged; Aged, 80 and over; Cell Line, Tumor; Cell Movement; Cell Proliferation; Collagen Type VI; G1 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Humans; Middle Aged; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Transcription Factors; Urinary Bladder Neoplasms; collagen type 6; collagen type VI alpha1; collagen type VI alpha2; gelatinase A; gelatinase B; immunoglobulin enhancer binding protein; mitogen activated protein kinase; mitogen activated protein kinase p38; pregnancy specific beta1 glycoprotein; protein kinase B; transcription factor AP 1; unclassified drug; Col6a1 protein, human; COL6A2 protein, human; collagen type 6; mitogen activated protein kinase p38; protein kinase B; transcription factor; adult; aged; Akt signaling; Article; bladder cancer; bladder cancer cell line; cancer growth; cell invasion; cell migration; cell proliferation; COL6A1 gene; COL6A2 gene; controlled study; down regulation; enzyme activity; enzyme phosphorylation; female; G1 phase cell cycle checkpoint; gene; gene expression; gene function; human; human cell; human tissue; major clinical study; male; MAPK signaling; muscle invasive bladder cancer; non muscle invasive bladder cancer; pathogenesis; priority journal; protein function; real time reverse transcription polymerase chain reaction; wound healing; bladder tumor; cell motion; cell proliferation; gene expression regulation; genetics; metabolism; middle aged; pathology; phosphorylation; signal transduction; tumor cell line; very elderly | English | 2021 | 2021-07 | 10.3892/ijo.2021.5217 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Person-Centered Care Environment Associated With Care Staff Outcomes in Long-Term Care Facilities | Background Although a general implementation of person-centered care in Korean long-term care delivery systems would be challenging, person-centered care has the potential to improve resident and staff outcomes through changes in current care services. However, little empirical evidence currently supports a positive relationship between person-centered care environments and staff outcomes. Purpose This study was designed to examine the relationship between person-centered care environments and staff outcomes, including job satisfaction and turnover intention, among care staff in Korean long-term care facilities. Methods This descriptive, correlational study used data from 235 care staff (94 nursing staff and 141 personal care workers) in 13 long-term care facilities in Korea. Data were collected using structured survey questionnaires, including items related to the person-centered care environment, job satisfaction, and turnover intention. Multilevel linear and logistic regression analyses were performed using Mplus Version 7.0. Results After controlling for individual (age, education, monthly income, position, shift work, and job tenure) and organizational (type of facility, location, ownership, bed size, and staffing levels) characteristics, a significant relationship was found between the person-centered care environment and job satisfaction and turnover intention among staff in Korean long-term care facilities. Conclusions/Implications for Practice The study findings indicate that working in a person-centered care environment is key to higher job satisfaction, which is a significant predictor of turnover intention among staff in long-term care facilities. To recruit and retain qualified staff to provide high-quality person-centered care in long-term care facilities, a supportive work environment is crucial. Fostering a person-centered care environment will ultimately improve quality of care for residents. | Choi, Jisun; Kim, Da Eun; Yoon, Ju Young | Kyung Hee Univ, Coll Nursing Sci, Seoul, South Korea; Kyungpook Natl Univ, Res Inst Nursing Sci, Coll Nursing, Daegu, South Korea; Seoul Natl Univ, Res Inst Nursing Sci, Coll Nursing, Seoul, South Korea | 55586222900; 57197746076; 55363051400 | jchoi14@khu.ac.kr;siahealth@gmail.com;yoon26@snu.ac.kr; | JOURNAL OF NURSING RESEARCH | J NURS RES | 1682-3141 | 1948-965X | 29 | 1 | SCIE;SSCI | NURSING | 2021 | 2.517 | 29.7 | 2.18 | 2025-07-30 | 12 | 16 | intent to leave; job satisfaction; nursing home; nurse staffing; person-centered care | JOB-SATISFACTION; CULTURE-CHANGE; TURNOVER; RETENTION; DEMENTIA; WORKING; HOMES | intent to leave; job satisfaction; nurse staffing; nursing home; person-centered care | Adult; Attitude of Health Personnel; Correlation of Data; Female; Health Personnel; Humans; Intention; Job Satisfaction; Logistic Models; Long-Term Care; Male; Middle Aged; Nursing Homes; Patient-Centered Care; Personnel Turnover; Republic of Korea; Surveys and Questionnaires; adult; article; correlational study; education; female; human; human experiment; job satisfaction; Korea; male; nursing home; nursing staff; questionnaire; resident; shift work; turnover rate; work environment; worker; behavior; health care personnel; health personnel attitude; job satisfaction; long term care; middle aged; nursing home; organization and management; patient care; personnel management; procedures; psychology; South Korea; statistical model | English | 2021 | 2021-02 | 10.1097/jnr.0000000000000412 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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