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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Article | Genome-wide identification, genomic organization, and expression profiling of the CONSTANS-like (COL) gene family in petunia under multiple stresses | Background CONSTANS-like (CO-like, COL) are putative zinc-finger transcription factors known to play vital role in various plant biological processes such as control of flowering time, regulation of plant growth and development and responses to stresses. However, no systematic analysis of COL family gene regarding the plant development and stress response has been previously performed in any solanaceous crop. In the present study, a comprehensive genome-wide analysis of COL family genes in petunia has been conducted to figure out their roles in development of organs and stress response. Results A total of 33 COL genes, 15 PaCOL genes in P. axillaris and 18 PiCOL genes in P. inflata, were identified in petunia. Subsequently, a genome-wide systematic analysis was performed in 15 PaCOL genes. Considering the domain composition and sequence similarity the 15 PaCOL and 18 PiCOL genes were phylogenetically classified into three groups those are conserved among the flowering plants. Moreover, all of the 15 PaCOL proteins were localized in nucleus. Furthermore, differential expression patterns of PaCOL genes were observed at different developmental stages of petunia. Additionally, transcript expression of 15 PaCOL genes under various abiotic and phytohormone treatments showed their response against stresses. Moreover, several cis-elements related to stress, light-responsive, hormone signaling were also detected in different PaCOL genes. Conclusion The phylogenetic clustering, organ specific expression pattern and stress responsive expression profile of conserved petunia COL genes indicating their involvement in plant growth and development and stress response mechanism. This work provide a significant foundation for understanding the biological roles of petunia COL genes in plant growth, development and in stress response. | Khatun, Khadiza; Debnath, Sourav; Robin, Arif Hasan Khan; Wai, Antt Htet; Nath, Ujjal Kumar; Lee, Do-Jin; Kim, Chang-Kil; Chung, Mi-Young | Patuakhali Sci & Technol Univ, Dept Biotechnol, Patuakhali 8602, Bangladesh; Patuakhali Sci & Technol Univ, Dept Biochem & Food Anal, Patuakhali 8602, Bangladesh; Bangladesh Agr Univ, Dept Genet & Plant Breeding, Mymensingh 2202, Bangladesh; Yangon Univ Educ, Dept Biol, Yangon 11041, Yangon Region, Myanmar; Sunchon Natl Univ, Dept Agr Educ, 255 Jungangno, Sunchon 57922, Jeonnam, South Korea; Kyungpook Natl Univ, Dept Hort, Daegu, South Korea | Wai, Antt/AAG-9099-2021; Robin, Arif/W-9293-2019 | 57190219662; 57288841100; 56073603800; 57196010294; 56460413300; 7406659787; 7409880701; 24821361600 | ckkim@knu.ac.kr;queen@sunhon.ac.kr;queen@sunchon.ac.kr; | BMC GENOMICS | BMC GENOMICS | 1471-2164 | 22 | 1 | SCIE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY;GENETICS & HEREDITY | 2021 | 4.558 | 28.3 | 0.86 | 2025-07-30 | 16 | 15 | Petunia; Genome-wide analysis; Constans-like gene (COL); Expression patterns; Abiotic stresses | FLOWERING-TIME GENE; TRANSCRIPTION FACTOR; REGULATORY ELEMENTS; MOLECULAR-BASIS; ABSCISIC-ACID; TWIN-SISTER; ARABIDOPSIS; FT; TOLERANCE; MUTANT | Abiotic stresses; Constans-like gene (COL); Expression patterns; Genome-wide analysis; Petunia | Gene Expression Regulation, Plant; Genomics; Petunia; Phylogeny; Plant Proteins; Stress, Physiological; phytohormone; plant protein; abiotic stress; angiosperm; Article; COL gene; cold treatment; controlled study; developmental stage; differential gene expression; DNA synthesis; drought tolerance; gene cluster; gene expression profiling; gene function; gene identification; gene sequence; gene structure; genetic conservation; genetic organization; genetic transcription; genome-wide association study; nonhuman; PaCOL gene; Petunia; Petunia axillaris; Petunia inflata; phylogeny; physiological stress; PiCOL gene; plant development; plant gene; plant growth; plant stress; protein localization; real time polymerase chain reaction; salinity; signal transduction; waterlogging; gene expression regulation; genetics; genomics; metabolism; Petunia | English | 2021 | 2021-10-08 | 10.1186/s12864-021-08019-w | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Identification of Campylobacter jejuni and Chlamydia psittaci from cockatiel (Nymphicus hollandicus) using metagenomics | Background In July 2015, the carcasses of 11 cockatiels were submitted for disease diagnosis to the Avian Disease Division of the Animal and Plant Quarantine Agency of Korea. The cockatiels, which appeared dehydrated and underweight, had exhibited severe diarrhea and 22 % mortality over 2 weeks. Traditional diagnosis did not reveal the causes of these symptoms. Methods We conducted metagenomics analysis on intestines and livers from the dead cockatiels using Illumina high-throughput sequencing. To obtain more accurate and longer contigs, which are required for further genetic characterization, we compared the results of three de novo assembly tools (metaSPAdes, MEGAHIT, and IDBA-UD). Results Sequence reads of Campylobacter jejuni (C. jejuni) and Chlamydia psittaci (C. psittaci) were present in most of the cockatiel samples. Either of these bacteria could cause the reported symptoms in psittaciformes. metaSPAdes (ver.3.14.1) identified the 1152 bp flaA gene of C. jejuni and the 1096 bp ompA gene of C. psittaci. Genetic analysis revealed that flaA of C. jejuni was recombinant between C. jejuni and Campylobacter coli, and that ompA of C. psittaci isolated from cockatiel was closely related to strains isolated from humans. Conclusions C. jejuni and C. psittaci were detected in cockatiels in the Republic of Korea using metagenomic analysis. This approach is useful for understanding pathogens of pet birds. Three de novo assemblers were compared to obtain accurate contigs from large quantities of reads, and sequences of C. jejuni and C. psittaci generated by metaSPAdes were analyzed. | Kim, Si-Hyeon; Kwon, Yong-Kuk; Park, Choi-Kyu; Kim, Hye-Ryoung | Anim & Plant Quarantine Agcy, Avian Dis Div, 177 Hyeoksin 8 Ro, Gyeongsangbuk Do 39660, Gimcheon Si, South Korea; Kyungpook Natl Univ, Coll Vet Med, Anim Dis Intervent Ctr, Daegu 41566, South Korea | Kim, Hyun/V-7593-2017; Kim, HyeRyoung/KHV-3905-2024 | 57222134529; 55449326300; 24768064900; 23982368400 | dvmkim77@korea.kr; | BMC GENOMICS | BMC GENOMICS | 1471-2164 | 22 | 1 | SCIE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY;GENETICS & HEREDITY | 2021 | 4.558 | 28.3 | 0.2 | 2025-07-30 | 2 | 3 | Pet birds; Cockatiel; Metagenomics; Chlamydiosis; Campylobacteriosis; Recombination; MetaSPAdes | PET BIRDS; INFECTION; CELL | Campylobacteriosis; Chlamydiosis; Cockatiel; Metagenomics; MetaSPAdes; Pet birds; Recombination | Animals; Campylobacter jejuni; Chlamydophila psittaci; Cockatoos; Humans; Metagenomics; Psittacosis; contig; animal tissue; Article; bacterial gene; bacterial strain; bacterium identification; Campylobacter coli; Campylobacter jejuni; Chlamydia psittaci; cockatiel; controlled study; diarrhea; Escherichia coli; flaA gene; gene sequence; genetic analysis; high throughput sequencing; intermethod comparison; intestine; liver; metagenomics; nonhuman; nucleotide sequence; nucleotide sequence; ompA gene; phylogeny; South Korea; underweight; animal; cockatoo; genetics; human; metagenomics; ornithosis | English | 2021 | 2021-11-06 | 10.1186/s12864-021-08122-y | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Inhibition of Antiviral Innate Immunity by Foot-and-Mouth Disease Virus Lpro through Interaction with the N-Terminal Domain of Swine RNase L | Foot-and-mouth disease virus (FMDV) is the pathogen of foot-and-mouth disease (FMD), which is a highly contagious disease in cloven-hoofed animals. To survive in the host, FMDV has evolved multiple strategies to antagonize host innate immune responses. In this study, we showed that the leader protease (Lpro) of FMDV, a papain-like proteinase, promoted viral replication by evading the antiviral interferon response through counteracting the 2',5'-oligoadenylate synthetase (OAS)/RNase L system. Specifically, we observed that the titers of Lpro deletion virus were significantly lower than those of wild type FMDV (FMDV-WT) in cultured cells. Our mechanistic studies demonstrated that Lpro interfered with the OAS/RNase L pathway by interacting with the N-terminal domain of swine RNase L (sRNase L). Remarkably, Lpro of FMDV exhibited species-specific binding to RNase L in that the interaction was observed only in swine cells, not human, monkey, or canine cells. Lastly, we presented evidence that by interacting with sRNase L, FMDV Lpro inhibited cellular apoptosis. Taken together, these results demonstrate a novel mechanism that Lpro utilizes to escape the OAS/RNase L-mediated antiviral defense pathway. IMPORTANCE FMDV is a picornavirus that causes a significant disease in agricultural animals. FMDV has developed diverse strategies to escape the host interferon response. Here, we show that Lpro of FMDV antagonizes the OAS/RNase L pathway, an important interferon effector pathway, by interacting with the N-terminal domain of sRNase L. Interestingly, such a virus-host interaction is species-specific because the interaction is detected only in swine cells, not in human, monkey, or canine cells. Furthermore, Lpro inhibits apoptosis through interacting with sRNase L. This study demonstrates a novel mechanism by which FMDV has evolved to inhibit host innate immune responses. | Sui, Chao; Jiang, Dandan; Wu, Xiangju; Liu, Sidang; Li, Feng; Pan, Li; Cong, Xiaoyan; Li, Juntong; Yoo, Dongwan; Rock, Daniel L.; Miller, Laura C.; Lee, Changhee; Du, Yijun; Qi, Jing | Shandong Acad Agr Sci, Inst Anim Sci & Vet Med, Shandong Key Lab Anim Dis Control & Breeding, Jinan, Shandong, Peoples R China; Shandong Agr Univ, Coll Anim Sci & Technol, Shandong Prov Key Lab Anim Biotechnol & Dis Contr, Tai An, Shandong, Peoples R China; South Dakota State Univ, Dept Biol & Microbiol, Brookings, SD 57007 USA; South Dakota State Univ, Dept Vet & Biomed Sci, Brookings, SD 57007 USA; Chinese Acad Agr Sci, Lanzhou Vet Res Inst, State Key Lab Vet Etiol Biol,Minist Agr, Natl Foot & Mouth Dis Reference Lab,Key Lab Anim, Lanzhou, Gansu, Peoples R China; Univ Illinois, Dept Pathobiol, Urbana, IL USA; ARS, Virus & Prion Res Unit, Natl Anim Dis Ctr, USDA, Ames, IA USA; Kyungpook Natl Univ, Sch Life Sci, Anim Virol Lab, BK21 Plus KNU Creat BioRes Grp, Daegu, South Korea | Uprety, Tirth/HII-3097-2022; Yoo, Dongwan/AAG-8884-2021; Miller, Laura/B-2268-2017 | 57190139708; 57205183479; 56096222400; 35211053900; 56402077200; 55729420700; 54398455000; 57225920747; 7103242554; 7102591007; 57203263769; 55700560700; 7402893902; 54403585000 | duyijun0916@163.com;qj-happy2008@163.com; | JOURNAL OF VIROLOGY | J VIROL | 0022-538X | 1098-5514 | 95 | 15 | SCIE | VIROLOGY | 2021 | 6.549 | 28.4 | 0.45 | 2025-07-30 | 8 | 5 | FMDV; RNase L; L-pro; antagonistic mechanism; ISGs; foot-and-mouth disease virus | 2-5A/RNASE L PATHWAY; LEADER PROTEINASE; INFECTED-CELLS; IDENTIFICATION; PROTEASE; BINDING; ACTIVATION; EXPRESSION; APOPTOSIS; CLEAVAGE | Antagonistic mechanism; FMDV; Foot-and-mouth disease virus; ISGs; L<sup>pro</sup>; RNase L | 2',5'-Oligoadenylate Synthetase; Animals; Apoptosis; Cell Line; Cricetinae; Dogs; Endopeptidases; Endoribonucleases; Foot-and-Mouth Disease; Foot-and-Mouth Disease Virus; Haplorhini; HEK293 Cells; Humans; Immune Evasion; Immunity, Innate; Madin Darby Canine Kidney Cells; Protein Domains; Swine; benzylsulfonyl fluoride; eukaryotic translation initiation factor 4gi; flag antibody; hemagglutinin; horseradish peroxidase; immunoglobulin G antibody; interferon; leader protease; nucleoprotein; papain-like protease; penicillin derivative; proteinase; reagent; ribonuclease L; streptomycin; trizol; unclassified drug; viral protein; 2',5' oligoadenylate synthetase; 2-5A-dependent ribonuclease; leader proteinase, foot-and-mouth disease virus; proteinase; ribonuclease; amino terminal sequence; animal cell; antiviral activity; apoptosis; Article; BHK cell line; chemiluminescence immunoassay; controlled study; CRISPR Cas system; dimerization; foot and mouth disease; Foot and mouth disease virus; gene overexpression; genetic transfection; HeLa cell line; human; human cell; immune response; immunoprecipitation; innate immunity; luciferase assay; MARC-145 cell line; nonhuman; PK-1 cell line; polyacrylamide gel electrophoresis; protein expression; real time polymerase chain reaction; sequence analysis; TUNEL assay; virus cell interaction; virus replication; Western blotting; animal; cell line; dog; Foot and mouth disease virus; genetics; hamster; Haplorhini; HEK293 cell line; immune evasion; immunology; innate immunity; MDCK cell line; metabolism; pig; protein domain; virology | English | 2021 | 2021-08 | 10.1128/jvi.00361-21 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Comparison of the protective effect of cytosolic and mitochondrial Peroxiredoxin 5 against glutamate-induced neuronal cell death | Objectives: Although glutamate is an essential factor in the neuronal system, excess glutamate can produce excitotoxicity. We previously reported that Peroxiredoxin 5 (Prx5) protects neuronal cells from glutamate toxicity via its antioxidant effects. However, it is unclear whether cytosolic or mitochondrial Prx5 provides greater neuroprotection. Here, we investigated differences in the neuroprotective effects of cytosolic and mitochondrial Prx5. Methods: We analyzed patterns of cytosolic and mitochondrial H2O2 generation in glutamate toxicity using HyPer protein. And then, we confirmed the change of intracellular ROS level and apoptosis with respective methods. The mitochondrial dynamics was assessed with confocal microscope imaging and western blotting. Results: We found that the level of mitochondrial H2O2 greatly increased compared to cytosolic H2O2 and it affected cytosolic H2O2 generation after glutamate treatment. In addition, we confirmed that mitochondrial Prx5 provides more effective neuroprotection than cytosolic Prx5. Discussion: Overall, our study reveals the mechanisms of cytosolic and mitochondrial ROS in glutamate toxicity. Our findings suggest that mitochondrial ROS and Prx5 are attractive therapeutic targets and that controlling these factors be useful for the prevention of neurodegenerative diseases. | Kim, Mi Hye; Kim, Da Yeon; Lee, Hong Jun; Park, Young-Ho; Huh, Jae-Won; Lee, Dong-Seok | Kyungpook Natl Univ, BK21 Plus KNU Creat BioRes Grp, Sch Life Sci, Daegu, South Korea; Kyungpook Natl Univ, Coll Nat Sci, Daegu, South Korea; Pusan Natl Univ, Stem Cell Res Ctr, Dept Physiol, Sch Med, Yangsan, South Korea; Chungbuk Natl Univ, Coll Med, Cheongju, South Korea; E Biogen Inc, Res Inst, Seoul, South Korea; Korea Res Inst Biosci & Biotechnol KRIBB, Futurist Anim Resource & Res Ctr, Cheongju, South Korea; Natl Primate Res Ctr, Korea Res Inst Biosci & Biotechnol KRIBB, Cheongju, South Korea | lee, wj/JNR-4926-2023 | 57193994930; 57200941034; 35215736300; 56246852400; 16645802900; 57210068061 | lee1@knu.ac.kr; | REDOX REPORT | REDOX REP | 1351-0002 | 1743-2928 | 26 | 1 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY | 2021 | 5.696 | 28.5 | 0.17 | 2025-07-30 | 3 | 3 | Cytosolic ROS; mitochondrial ROS; apoptosis; Peroxiredoxin 5; glutamate; HT22; Hyper; Hydrogen peroxide | apoptosis; Cytosolic ROS; glutamate; HT22; Hydrogen peroxide; Hyper; mitochondrial ROS; Peroxiredoxin 5 | Apoptosis; Cell Death; Glutamic Acid; Hydrogen Peroxide; Neuroprotective Agents; Oxidative Stress; Peroxiredoxins; Reactive Oxygen Species; beta actin; calcineurin; caspase 3; dynamin I; glutamic acid; hydrogen peroxide; lentivirus vector; mitofusin 1; mitofusin 2; peroxiredoxin 5; pyroxylin; reactive oxygen metabolite; Taq polymerase; glutamic acid; hydrogen peroxide; neuroprotective agent; peroxiredoxin; reactive oxygen metabolite; animal cell; animal experiment; antioxidant activity; apoptosis; Article; cell protection; cell viability; clinical assessment; comparative study; confocal microscopy; controlled study; cytosol; drug efficacy; drug mechanism; flow cytometry; fluorometry; HT22 cell line; mitochondrial dynamics; mitochondrial targeting signal; mitochondrion; mouse; nerve cell necrosis; neuroprotection; nonhuman; priority journal; protein function; Western blotting; cell death; metabolism; oxidative stress | English | 2021 | 2021-01-01 | 10.1080/13510002.2021.1901028 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Multiphase Numerical Study of Meniscus Vortex Flows for Wide Range of Casting Speed in Water Model of Continuous Casting Mold Through Appropriate Modeling for Turbulence | Slag entrainments in a continuous casting mold result in serious defects in steel products. This slag entrainment is directly connected with the meniscus vortex accompanying a large meniscus deformation. To exactly evaluate the air or slag entrainments, it is critical that numerical studies can reproduce the meniscus vortex deformation. In our study, we found that Reynolds-averaged Navier-Stokes (RANS) turbulent models failed to reproduce the meniscus vortex deformation, and furthermore, the laminar model underestimated the meniscus vortex depth at high-casting conditions over 1.4 m/min. In this study, we proposed the hybrid and large eddy simulation models to correctly predict the distortion for real physics of the meniscus vortex. In contrast to the laminar and RANS turbulent models, the proposed models show strong agreement with the experiment even in high-casting conditions. | Lee, Jong Hui; Han, Sangwoo; Cho, Hyun-Jin; Park, Il Seouk | Kyungpook Natl Univ, Dept Mech Engn, 80 Daehakro, Daegu 41566, South Korea; Steelmaking Res Grp, Tech Res Labs Pohang Res Lab, POSCO, 6261 Donghaeanro, Pohang 37859, Gyeongbuk, South Korea; Kyungpook Natl Univ, Sch Mech Engn, 80 Daehakro, Daegu 41566, South Korea | Lee, Jong Hui/JFT-0292-2023 | 57204669495; 55356225500; 57203005367; 50262800000 | einstein@knu.ac.kr; | METALLURGICAL AND MATERIALS TRANSACTIONS B-PROCESS METALLURGY AND MATERIALS PROCESSING SCIENCE | METALL MATER TRANS B | 1073-5615 | 1543-1916 | 52 | 4 | SCIE | MATERIALS SCIENCE, MULTIDISCIPLINARY;METALLURGY & METALLURGICAL ENGINEERING | 2021 | 2.872 | 28.5 | 0.48 | 2025-07-30 | 8 | 9 | AIR-CORE PHENOMENON; STEEL; TRANSITION; DYNAMICS; AIRFOILS; HEAT; TANK | Continuous casting; Deformation; Large eddy simulation; Molds; Navier Stokes equations; Slags; Appropriate models; Casting conditions; Continuous casting mold; Meniscus deformation; Reynolds averaged; Slag entrainment; Steel products; Turbulent models; Vortex flow | English | 2021 | 2021-08 | 10.1007/s11663-021-02229-z | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Numerical and Experimental Study of the Meniscus Vortex Core in a Water Model of Continuous Casting Mold | Slag entrainments in a continuous casting mold result in serious defects in steel products. Most previous studies concentrated on the magnitude of meniscus velocity or transient roll cell motion to investigate the cause of slag entrainment. However, slag entrainment is more directly connected with the meniscus vortex, which accompanies a meniscus deformation (e.g., vortex dimple or core). Most previous numerical studies on the meniscus vortex were conducted using a single-phase flow analysis; thus, the effect of meniscus deformation was never examined. This study conducts a multiphase flow simulation by employing a free-surface-capturing technique, and succeeds in reproducing the meniscus vortex core in the mold. The core depth and onset condition for the meniscus vortex obtained by the present numerical study show good agreements with the experimental results. The vorticity distribution on the mold meniscus and meniscus vortex patterns according to flow asymmetry are also dealt with herein. | Lee, Jong Hui; Han, Sangwoo; Cho, Hyun-Jin; Park, Il Seouk | Kyungpook Natl Univ, Dept Mech Engn, 80 Daehakro, Daegu 41566, South Korea; POSCO, Tech Res Labs, Pohang Res Lab, Steelmaking Res Grp, 6261 Donghaeanro, Pohang 37859, Gyeongbuk, South Korea; Kyungpook Natl Univ, Sch Mech Engn, 80 Daehakro, Daegu 41566, South Korea | Lee, Jong Hui/JFT-0292-2023 | 57204669495; 55356225500; 57203005367; 50262800000 | einstein@knu.ac.kr; | METALLURGICAL AND MATERIALS TRANSACTIONS B-PROCESS METALLURGY AND MATERIALS PROCESSING SCIENCE | METALL MATER TRANS B | 1073-5615 | 1543-1916 | 52 | 1 | SCIE | MATERIALS SCIENCE, MULTIDISCIPLINARY;METALLURGY & METALLURGICAL ENGINEERING | 2021 | 2.872 | 28.5 | 1.36 | 2025-07-30 | 23 | 23 | FLOW PATTERNS; AIR-CORE; STEEL; SIMULATION; DYNAMICS; FIELD; HEAT | Continuous casting; Deformation; Molds; Slags; Continuous casting mold; Free surface capturing; Meniscus deformation; Meniscus velocities; Numerical and experimental study; Single-phase flow; Slag entrainment; Vorticity distribution; Vortex flow | English | 2021 | 2021-02 | 10.1007/s11663-020-02006-4 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | AI-Enabled Blockchain-Based Access Control for Malicious Attacks Detection and Mitigation in IoE | In Internet of Everything (IoE), malicious attacks detection and mitigation are important issues. These issues can be resolved through an access control framework where two entities first authenticate each other prior to establishing any secret key for their secure communication. The sensing data of various smart devices in an IoE environment are processed securely at the nearby fog servers and at the same time legitimate users can also access the real-time data directly from designated smart devices through access control mechanism. We first discuss various attack trends in an IoE environment. After that, we discuss evolution of the blockchain technology in the IoE. An artificial intelligence based blockchain-envisioned access control framework for malicious attacks detection and mitigation has been suggested to secure the IoE environment. Finally, a blockchain-based implementation has been conducted on the proposed blockchain-envisioned access control framework for measuring the computational time needed for varying number of blocks mined in the blockchain and also for varying number of transactions per block. | Bera, Basudeb; Das, Ashok Kumar; Obaidat, Mohammad S.; Vijayakumar, Pandi; Hsiao, Kuei-Fang; Park, YoungHo | Int Inst Informat Technol, Hyderabad, India; Int Inst Informat Technol, Ctr Secur Theory & Algorithm Res, Hyderabad, India; Univ Sharjah, Coll Comp & Informat, Sharjah, U Arab Emirates; Univ Coll Engn Tindivanam, Chennai, Tamil Nadu, India; Univ Sharjah, Dept Informat Syst, Sharjah, U Arab Emirates; Kyungpook Natl Univ, Sch Elect Engn, Daegu, South Korea | ; Pandi, Vijayakumar/Y-4636-2019; Obaidat, Life Fellow of IEEE, Mohammad/KBC-2747-2024; Bera, Basudeb/ACC-6233-2022; Das, Ashok Kumar/U-2790-2019 | 57214777647; 55450732800; 7005628795; 57189497709; 36088895500; 56962990300 | basudeb.bera@research.iiit.ac.in;iitkgp.akdas@gmail.com;msobaidat@gmail.com;vijibond2000@gmail.com;kfhsiao@mail.mcu.edu.tw;parkyh@knu.ac.kr; | IEEE CONSUMER ELECTRONICS MAGAZINE | IEEE CONSUM ELECTR M | 2162-2248 | 2162-2256 | 10 | 5 | SCIE | COMPUTER SCIENCE, HARDWARE & ARCHITECTURE;ENGINEERING, ELECTRICAL & ELECTRONIC;TELECOMMUNICATIONS | 2021 | 4.135 | 28.7 | 1.85 | 2025-07-30 | 20 | 33 | CONTROL SCHEME; SECURITY; INTERNET | Artificial intelligence; Blockchain; Access control mechanism; Computational time; Control framework; Legitimate users; Malicious attack; Number of blocks; Real-time data; Various attacks; Access control | English | 2021 | 2021-09-01 | 10.1109/mce.2020.3040541 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Generalized Killing-Ricci Tensor for Real Hypersurfaces in Complex Hyperbolic Two-Plane Grassmannians | In this paper, first we introduce a new notion of generalized Killing-Ricci tensor for a real hypersurface M in complex hyperbolic two-plane Grassmannians SU2,m/S(U2.Um). Next we give a complete classification for Hopf real hypersurfaces in complex hyperbolic two-plane Grassmannians SU2,m/S(U2.Um) with generalized Killing-Ricci tensor. | Suh, Young Jin | Kyungpook Natl Univ, Dept Math, Taegu 41566, South Korea; Kyungpook Natl Univ, RIRCM, Taegu 41566, South Korea | 7202260479 | yjsuh@knu.ac.kr; | MEDITERRANEAN JOURNAL OF MATHEMATICS | MEDITERR J MATH | 1660-5446 | 1660-5454 | 18 | 3 | SCIE | MATHEMATICS, APPLIED;MATHEMATICS | 2021 | 1.305 | 28.7 | 2.24 | 2025-07-30 | 9 | 10 | Generalized Killing-Ricci tensor; Ricci curvature; cyclic parallel Ricci tensor; geodesic Reeb flow; Hopf hypersurface; Primary 53C40; Secondary 53C55 | SPACES | cyclic parallel Ricci tensor; Generalized Killing–Ricci tensor; geodesic Reeb flow; Hopf hypersurface; Ricci curvature | English | 2021 | 2021-03-19 | 10.1007/s00009-021-01724-6 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Gradient Yamabe and Gradient m-Quasi Einstein Metrics on Three-dimensional Cosymplectic Manifolds | In this paper, we characterize the gradient Yamabe and the gradient m-quasi Einstein solitons within the framework of three-dimensional cosymplectic manifolds. | De, Uday Chand; Chaubey, Sudhakar K.; Suh, Young Jin | Univ Calcutta, Dept Pure Math, 35 Ballygaunge Circular Rd, Kolkata 700019, W Bengal, India; Univ Technol & Appl Sci Shinas, Dept Informat Technol, Sect Math, POB 77, Shinas 324, Oman; Kyungpook Natl Univ, Dept Math, Daegu 41566, South Korea; Kyungpook Natl Univ, RIRCM, Daegu 41566, South Korea | Chaubey, S./ABB-6952-2021 | 7007046738; 36117508600; 7202260479 | uc_de@yahoo.com;sudhakar.chaubey@shct.edu.om;yjsuh@knu.ac.kr; | MEDITERRANEAN JOURNAL OF MATHEMATICS | MEDITERR J MATH | 1660-5446 | 1660-5454 | 18 | 3 | SCIE | MATHEMATICS, APPLIED;MATHEMATICS | 2021 | 1.305 | 28.7 | 5.37 | 2025-07-30 | 31 | 32 | Three-dimensional cosymplectic manifolds; gradient Yamabe solitons; gradient m-quasi Einstein solitons; product structures; 53B30; 53B50; 53C15 | RICCI SOLITONS; COMPACT; CLASSIFICATION; TOPOLOGY; GEOMETRY | gradient m-quasi Einstein solitons; gradient Yamabe solitons; product structures; Three-dimensional cosymplectic manifolds | English | 2021 | 2021-03-18 | 10.1007/s00009-021-01720-w | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | Article | Costunolide suppresses melanoma growth via the AKT/mTOR pathway in vitro and in vivo | Melanoma is the most common type of skin cancer and its incidence is rapidly increasing. AKT, and its related signaling pathways, are highly activated in many cancers including lung, colon, and esophageal cancers. Costunolide (CTD) is a sesquiterpene lactone that has been reported to possess neuroprotective, anti-inflammatory, and anti-cancer properties. However, the target and mechanism underlying its efficacy in melanoma have not been identified. In this study, we elucidated the mechanism behind the anti-cancer effect of CTD in melanoma in vitro and in vivo by identifying CTD as an AKT inhibitor. We first verified that p-AKT and AKT are highly expressed in melanoma patient tissues and cell lines. CTD significantly inhibited the proliferation, migration, and invasion of melanoma cells including SK-MEL-5, SK-MEL-28, and A375 that are overexpressed p-AKT and AKT proteins. We investigated the mechanism of CTD using a computational docking modeling, pull-down, and site directed mutagenesis assay. CTD directly bound to AKT thereby arresting cell cycle at the G1 phase, and inducing the apoptosis of melanoma cells. In addition, CTD regulated the G1 phase and apoptosis biomarkers, and inhibited the expression of AKT/mTOR/GSK3b/p70S6K/4EBP cascade proteins. After reducing AKT expression in melanoma cells, cell growth was significantly decreased and CTD did not showed further inhibitory effects. Furthermore, CTD administration suppressed tumor growth and weight in cell-derived xenograft mice models in vivo without body weight loss and inhibited the expression of Ki-67, p-AKT, and p70S6K in tumor tissues. In summary, our study implied that CTD inhibited melanoma progression in vitro and in vivo. In this study, we reported that CTD could affect melanoma growth by targeting AKT. Therefore, CTD has considerable potential as a drug for melanoma therapy. | Huang, Hai; Yi, Junkoo; Park, Song; Zhang, Haibo; Kim, Eungyung; Park, Sijun; Kwon, Wookbong; Jang, Soyoung; Zhang, Xiujuan; Chen, Hanyong; Choi, Seong-Kyoon; Kim, Sung-hyun; Liu, Kangddong; Dong, Zigang; Lee, Mee-Hyun; Ryoo, Zaeyoung; Kim, Myoung Ok | Kyungpook Natl Univ, Dept Anim Sci & Biotechnol, Sangju Si 37224, Gyeongsang Buk, South Korea; Gyeongbuk Livestock Res Inst, Yeongju 36052, South Korea; Kyungpook Natl Univ, Shool Life Sci, Daegu, South Korea; DGIST, Core Prot Resources Ctr, Daegu, South Korea; DGIST, Dept Brian & Cognit Sci, Daegu, South Korea; Fudan Univ, Huashan Hosp, Dept Pulm & Crit Care Med, Shanghai 200040, Peoples R China; Univ Minnesota, Hormel Inst, 801 16th Ave NE, Austin, MN 55912 USA; DGIST, Div Biotechnol, Daegu, South Korea; Korea Polytech Coll, Dept Biomed Anal, Chungnam, South Korea; Zhengzhou Univ Zhengzhou, Basic Med Coll, Zhengzhou, Henan, Peoples R China; Dongshin Univ, Coll Korean Med, Naju, Jeollanamdo, South Korea | ; Yi, Junkoo/JBR-8507-2023 | jaewoong64@hanmail.net;ok4325@knu.ac.kr; | AMERICAN JOURNAL OF CANCER RESEARCH | AM J CANCER RES | 2156-6976 | 11 | 4 | SCIE | ONCOLOGY | 2021 | 5.942 | 28.8 | 7 | Costunolide; melanoma; AKT; mTOR pathway; proliferation; xenograft models | METASTATIC MELANOMA; ACQUIRED-RESISTANCE; CANCER STATISTICS; SIGNALING PATHWAY; BREAST-CANCER; BRAF; APOPTOSIS; KINASE; PROGRESSION; ACTIVATION | English | 2021 | 2021 | 바로가기 | 바로가기 | ||||||||||||
| ○ | ○ | Article | A New Type of Wireless Transmission Based on Digital Direct Modulation for Use in Partially Implantable Hearing Aids | In this study, we developed a new type of wireless transmission system for use in partially implantable hearing aids. This system was designed for miniaturization and low distortion, and features direct digital modulation. The sigma-delta output, which has a high SNR due to oversampling and noise shaping technology, is used as the data signal and is transmitted using a wireless transmission system to the implant unit through OOK without restoration as an audio signal, thus eliminating the need for additional circuits (i.e., LPF and a reference voltage supply circuit) and improving the ease of implantation and reliability of the circuit. We selected a carrier frequency of 27 MHz after analysis of carrier attenuation by human tissue, and designed the communication coil with reference to both the geometry and required communication distance. Circuit design and simulation for wireless transmission were performed using Multisim 13.0. The system was fabricated based on the circuit design; the size of the device board was 13 mm x 13 mm, the size of the implanted part was 9 mm x 9 mm, the diameter of the transmitting/receiving coil was 26 mm, and the thicknesses of these coils were 0.5 and 0.3 mm, respectively. The difference (error) between the detected and simulation waveforms was about 5%, and was thought to be due to the tolerances of the fabricated communication coil and elements (resistors, capacitors, etc.) used in the circuit configuration of the system. The number of windings was reduced more than 9-fold compared to the communication coil described by Taghavi et al. The measured THD was <1% in the frequency band from 100 Hz to 10 kHz, thus easily meeting the standard specification for hearing aids. | Kim, Jong-Hoon; Cho, Jin-Ho; Seong, Ki-Woong; Kim, Myoung-Nam | Kyungpook Natl Univ, Inst Biomed Engn Res, 680 Gukchaebosang Ro, Daegu 41944, South Korea; Kyungpook Natl Univ, Dept Biomed Engn, 130 Dongdeok Ro, Daegu 41944, South Korea; Kyungpook Natl Univ, Sch Med, Dept Biomed Engn, 680 Gukchaebosang Ro, Daegu 41944, South Korea | ; Kim, Sunghoon/Z-2981-2019 | 57201854156; 57388235200; 23968197900; 57212315655 | jh850526@naver.com;jhcho@ee.knu.ac.kr;seongkw@ee.knu.ac.kr;kimmn@knu.ac.kr; | SENSORS | SENSORS-BASEL | 1424-8220 | 21 | 8 | SCIE | CHEMISTRY, ANALYTICAL;ENGINEERING, ELECTRICAL & ELECTRONIC;INSTRUMENTS & INSTRUMENTATION | 2021 | 3.847 | 28.9 | 0.07 | 2025-07-30 | 0 | 1 | partially implantable hearing aids; inductive coupling; wireless transmission system; low distortion; sigma-delta modulation | ENERGY; DESIGN | Inductive coupling; Low distortion; Partially implantable hearing aids; Sigma-delta modulation; Wireless transmission system | Equipment Design; Hearing Aids; Humans; Miniaturization; Prostheses and Implants; Reproducibility of Results; Wireless Technology; Audio acoustics; Hearing aids; Integrated circuit manufacture; Modulation; Signal to noise ratio; Circuit configurations; Communication distance; Digital modulations; Direct modulation; Reference voltages; Standard specifications; Wireless transmission systems; Wireless transmissions; equipment design; hearing aid; human; miniaturization; prostheses and orthoses; reproducibility; wireless communication; Audition | English | 2021 | 2021-04 | 10.3390/s21082809 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | A Novel Simplified System to Estimate Lower-Limb Joint Moments during Sit-to-Stand | To provide effective diagnosis and rehabilitation, the evaluation of joint moments during sit-to-stand is essential. The conventional systems for the evaluation, which use motion capture cameras, are quite accurate. However, the systems are not widely used in clinics due to their high cost, inconvenience, and the fact they require lots of space. To solve these problems, some studies have attempted to use inertial sensors only, but they were still inconvenient and inaccurate with asymmetric weight-bearing. We propose a novel joint moment estimation system that can evaluate both symmetric and asymmetric sit-to-stands. To make a simplified system, the proposal is based on a kinematic model that estimates segment angles using a single inertial sensor attached to the shank and a force plate. The system was evaluated with 16 healthy people through symmetric and asymmetric weight-bearing sit-to-stand. The results showed that the proposed system (1) has good accuracy in estimating joint moments (root mean square error 0.99) and (2) is clinically relevant due to its simplicity and applicability of asymmetric sit-to-stand. | Hwang, Seoyoon; Choi, Seoyoung; Lee, Yang-Soo; Kim, Jonghyun | Sungkyunkwan Univ, Sch Mech Engn, Suwon 16419, South Korea; DGIST Daegu Gyeongbuk Inst Sci & Technol, Dept Robot Engn, Daegu 42988, South Korea; Kyungpook Natl Univ, Sch Med, Dept Rehabil Med, Daegu 41944, South Korea | 57213588682; 57192913526; 57202952463; 57196195220 | sy.hwang@skku.edu;sychoi@dgist.ac.kr;leeyangsoo@knu.ac.kr;jonghyunkim@skku.edu; | SENSORS | SENSORS-BASEL | 1424-8220 | 21 | 2 | SCIE | CHEMISTRY, ANALYTICAL;ENGINEERING, ELECTRICAL & ELECTRONIC;INSTRUMENTS & INSTRUMENTATION | 2021 | 3.847 | 28.9 | 0.29 | 2025-07-30 | 5 | 6 | asymmetric weight-bearing motion; inertial sensor; joint moment; kinematic model; segment angle; sit-to-stand | HIP-ARTHROPLASTY; SEAT HEIGHTS; MOVEMENT; ASYMMETRY; SYMMETRY; INDIVIDUALS; STRENGTH; PLATFORM; TORQUES; FORCES | Asymmetric weight-bearing motion; Inertial sensor; Joint moment; Kinematic model; Segment angle; Sit-to-stand | Adult; Biomechanical Phenomena; Humans; Joints; Knee Joint; Lower Extremity; Movement; Weight-Bearing; Inertial navigation systems; Kinematics; Mean square error; Conventional systems; Correlation coefficient; Healthy people; Inertial sensor; Kinematic model; Root mean square errors; Sit-to-stand; Weight bearing; adult; biomechanics; human; joint; knee; lower limb; movement (physiology); weight bearing; Joints (anatomy) | English | 2021 | 2021-01 | 10.3390/s21020521 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | A Novel Versatile Approach for Underwater Conformal Volumetric Array Design | In this study, we present a novel approach to the design of a conformal volumetric array composed of M x N convex subarrays in two orthogonal curvilinear directions for underwater acoustic imaging for mine detection. Our design targets require that the proposed array transducer has three-dimensional half-power beamwidths of 85 degrees and 25 degrees in either of its convex subarray parts, while also reaching a peak transmitting voltage response above 147 dB. The radiated sound pressure of the subarrays was independently derived as a function of their geometrical parameters. The resulting directional factors were then combined to analyze the beam profile of the entire array. The design was finally optimized to minimize the ripple level. To validate this theoretical design, the structure was modeled and analyzed using the finite element method. The comparison between the resulting beam pattern from the finite element analysis and the analytical computation showed an excellent compliance. The method advanced is a simple and systematic analytical model to facilitate the development of new conformal volumetric arrays for underwater mine detection. | Yusuf, Taofeek Ayotunde; Pyo, Seonghun; Roh, Yongrae | Kyungpook Natl Univ, Sch Mech Engn, Daegu 41556, South Korea | Yusuf, Taofeek/G-7512-2017 | 57192692590; 56715171600; 7102361870 | yustaofeekay@yahoo.com;nasgool@naver.com;yryong@knu.ac.kr; | SENSORS | SENSORS-BASEL | 1424-8220 | 21 | 11 | SCIE | CHEMISTRY, ANALYTICAL;ENGINEERING, ELECTRICAL & ELECTRONIC;INSTRUMENTS & INSTRUMENTATION | 2021 | 3.847 | 28.9 | 0.07 | 2025-07-30 | 1 | 1 | conformal volumetric array; optimization; beamwidth; ripple; FEA | CLASSIFICATION; ANTENNA | Beamwidth; Conformal volumetric array; FEA; Optimization; Ripple | Geometry; Underwater imaging; Array design; Array transducers; Beam widths; Conformal volumetric array; Half power beamwidth; Mine detections; Optimisations; Ripple; Subarray; Volumetric arrays; Finite element method | English | 2021 | 2021-06 | 10.3390/s21113591 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | A Prosthetic Socket with Active Volume Compensation for Amputated Lower Limb | Typically, the actual volume of the residual limb changes over time. This causes the prosthesis to not fit, and then pain and skin disease. In this study, a prosthetic socket was developed to compensate for the volume change of the residual limb. Using an inflatable air bladder, the proposed socket monitors the pressure in the socket and keeps the pressure distribution uniform and constant while walking. The socket has three air bladders on anterior and posterior tibia areas, a latching type 3-way pneumatic valve and a portable control device. In the paper, the mechanical properties of the air bladder were investigated, and the electromagnetic analysis was performed to design the pneumatic valve. The controller is based on a hysteresis control algorithm with a closed loop, which keeps the pressure in the socket close to the initial set point over a long period of time. In experiments, the proposed prosthesis was tested through the gait simulator that can imitate a human's gait cycle. The active volume compensation of the socket was successfully verified during repetitive gait cycle using the weight loads of 50, 70, and 90 kg and the residual limb model with a variety of volumes. It was confirmed that the pressure of the residual limb recovered to the initial state through the active control. The pressure inside the socket had a steady state error of less than 0.75% even if the volume of the residual limb was changed from -7% to +7%. | Seo, Ji-Hyeon; Lee, Hyuk-Jin; Seo, Dong-Wook; Lee, Dong-Kyu; Kwon, Oh-Won; Kwak, Moon-Kyu; Lee, Kang-Ho | Korea Inst Machinery & Mat, Daegu Res Ctr Med Devices, Daegu 42994, South Korea; Kyungpook Natl Univ, Sch Mech Engn, Coll Engn, Daegu 41566, South Korea; Korea Maritime & Ocean Univ, Dept Radio Commun Engn, Interdisciplinary Major Maritime AI Convergence, Busan 49112, South Korea | Kwak, Moon/AGQ-6058-2022; Seo, Dong-Wook/Y-9005-2018 | 57221389605; 59856410300; 35171443100; 8673376500; 57026875700; 57203947984; 56697620500 | gch02236@kimm.re.kr;machlhj@kimm.re.kr;dwseo@kmou.ac.kr;dongkyu@kimm.re.kr;owkwon@kimm.re.kr;mkkwak@knu.ac.kr;kangholee6@kimm.re.kr; | SENSORS | SENSORS-BASEL | 1424-8220 | 21 | 2 | SCIE | CHEMISTRY, ANALYTICAL;ENGINEERING, ELECTRICAL & ELECTRONIC;INSTRUMENTS & INSTRUMENTATION | 2021 | 3.847 | 28.9 | 0.81 | 2025-07-30 | 13 | 11 | lower limb prosthesis; prosthetic socket; active control; volume compensation; air bladder; air flow; 3-way pneumatic valve | 3-way pneumatic valve; Active control; Air bladder; Air flow; Lower limb prosthesis; Prosthetic socket; Volume compensation | Amputation Stumps; Artificial Limbs; Humans; Lower Extremity; Prosthesis Design; Tibia; Pneumatic equipment; Pneumatics; Pressure control; Valves (mechanical); Active volumes; Control device; Electromagnetic analysis; Gait simulators; Hysteresis control; Pneumatic valve; Prosthetic sockets; Steady state errors; amputation stump; human; limb prosthesis; lower limb; prosthesis design; tibia; Artificial limbs | English | 2021 | 2021-01 | 10.3390/s21020407 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | A Schottky-Type Metal-Semiconductor-Metal Al0.24Ga0.76N UV Sensor Prepared by Using Selective Annealing | Asymmetric metal-semiconductor-metal (MSM) aluminum gallium nitride (AlGaN) UV sensors with 24% Al were fabricated using a selective annealing technique that dramatically reduced the dark current density and improved the ohmic behavior and performance compared to a non-annealed sensor. Its dark current density at a bias of -2.0 V and UV-to-visible rejection ratio (UVRR) at a bias of -7.0 V were 8.5 x 10(-10) A/cm(2) and 672, respectively, which are significant improvements over a non-annealed sensor with a dark current density of 1.3 x 10(-7) A/cm(2) and UVRR of 84, respectively. The results of a transmission electron microscopy analysis demonstrate that the annealing process caused interdiffusion between the metal layers; the contact behavior between Ti/Al/Ni/Au and AlGaN changed from rectifying to ohmic behavior. The findings from an X-ray photoelectron spectroscopy analysis revealed that the O 1s binding energy peak intensity associated with Ga oxide, which causes current leakage from the AlGaN surface, decreased from around 846 to 598 counts/s after selective annealing. | Park, Byeong-Jun; Seol, Jeong-Hoon; Hahm, Sung-Ho | Kyungpook Natl Univ, Sch Elect & Elect Engn, Daegu 41566, South Korea | 58596544800; 57191055561; 7006791831 | qudwns27@knu.ac.kr;jeonghoonseol@knu.ac.kr;shhahm@knu.ac.kr; | SENSORS | SENSORS-BASEL | 1424-8220 | 21 | 12 | SCIE | CHEMISTRY, ANALYTICAL;ENGINEERING, ELECTRICAL & ELECTRONIC;INSTRUMENTS & INSTRUMENTATION | 2021 | 3.847 | 28.9 | 0.22 | 2025-07-30 | 3 | 3 | aluminum gallium nitride (AlGaN); UV; UV-to-visible rejection ratio (UVRR); local breakdown | OHMIC CONTACT FORMATION; P-I-N; GAN; PHOTODETECTOR; SURFACE; STATES; HEMT | Aluminum gallium nitride (AlGaN); Local breakdown; UV; UV-to-visible rejection ratio (UVRR) | Aluminum gallium nitride; Aluminum metallography; Annealing; Binding energy; Current density; Dark currents; Gold alloys; Gold metallography; High resolution transmission electron microscopy; III-V semiconductors; Metals; Nickel metallography; Semiconductor alloys; Titanium alloys; Titanium metallography; Ultraviolet devices; Uranium metallography; Vanadium metallography; Wide band gap semiconductors; X ray photoelectron spectroscopy; Annealing process; Annealing techniques; Contact behavior; Current leakage; Metal semiconductor metal; Ohmic behavior; Rejection ratios; Transmission electron; Metal analysis | English | 2021 | 2021-06 | 10.3390/s21124243 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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