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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Article | Protein kinase CK2 activates Nrf2 via autophagic degradation of Keap1 and activation of AMPK in human cancer cells | Protein kinase CK2 downregulation induces premature senescence in various human cell types via activation of the reactive oxygen species (ROS)-p53-p21(Cip1/)(WAF1) pathway. The transcription factor "nuclear factor erythroid 2-related factor 2 '' (Nrf2) plays an important role in maintaining intracellular redox homeostasis. In this study, Nrf2 overexpression attenuated CK2 downregulation-induced ROS production and senescence markers including SA-beta-gal staining and activation of p53-p21(Cip1/)(WAF1) in human breast (MCF-7) and colon (HCT116) cancer cells. CK2 downregulation reduced the transcription of Nrf2 target genes, such as glutathione S transferase, glutathione peroxidase 2, and glutathione reductase 1. Furthermore, CK2 downregulation destabilized Nrf2 protein via inhibiting autophagic degradation of Kelch-like ECH-associated protein 1 (Keap1). Finally, CK2 downregulation decreased the nuclear import of Nrf2 by deactivating AMP-activated protein kinase (AMPK). Collectively, our data suggest that both Keap1 stabilization and AMPK inactivation are associated with decreased activity of Nrf2 in CK2 downregulation-induced cellular senescence. | Jang, Da Eun; Song, Junbin; Park, Jeong-Woo; Yoon, Soo-Hyun; Bae, Young-Seuk | Kyungpook Natl Univ, Sch Life Sci, BK2 Plus KNU Creat BioRes Grp, Daegu 41566, South Korea; Kyungpook Natl Univ, Coll Pharm, Res Inst Pharmaceut Sci, Daegu 41566, South Korea | 57216972169; 57216972249; 57202928272; 34968837000; 8230659600 | ysbae@knu.ac.kr; | BMB REPORTS | BMB REP | 1976-6696 | 1976-670X | 53 | 5 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY | 2020 | 4.778 | 33.1 | 0.8 | 2025-06-25 | 17 | 15 | AMPK; Antioxidants; CK2; Keap1; Nrf2 | REGULATION-MEDIATED SENESCENCE; TRANSCRIPTION FACTOR NRF2; HUMAN COLON-CANCER; DOWN-REGULATION; CELLULAR SENESCENCE; INACTIVATION; ACCUMULATION; MECHANISMS; NUTRIENT; STRESS | AMPK; Antioxidants; CK2; Keap1; Nrf2 | AMP-Activated Protein Kinases; Autophagy; Casein Kinase II; Humans; Kelch-Like ECH-Associated Protein 1; NF-E2-Related Factor 2; Tumor Cells, Cultured; casein kinase II; hydroxymethylglutaryl coenzyme A reductase kinase; KEAP1 protein, human; kelch like ECH associated protein 1; NFE2L2 protein, human; transcription factor Nrf2; autophagy; human; metabolism; tumor cell culture | English | 2020 | 2020-05-31 | 10.5483/bmbrep.2020.53.5.044 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Regulation of alternative macrophage activation by MSCs derived hypoxic conditioned medium, via the TGF-β1/Smad3 pathway | Macrophages are re-educated and polarized in response to myocardial infarction (MI). The M2 anti-inflammatory phenotype is a known dominator of late stage MI. Mesenchymal stem cells (MSCs) represent a promising tool for cell therapy, particularly heart related diseases. In general, MSCs induce alteration of the macrophage subtype from M1 to M2, both in vitro and in vivo. We conjectured that hypoxic conditions can promote secretome productivity of MSCs. Hypoxia induces TGF-beta 1 expression, and TGF-beta 1 mediates M2 macrophage polarization for anti-inflammation and angiogenesis in infarcted areas. We hypothesized that macrophages undergo advanced M2 polarization after exposure to MSCs in hypoxia. Treatment of MSCs derived hypoxic conditioned medium (hypo-CM) promoted M2 phenotype and neovascularization through the TGF-beta 1/Smad3 pathway. In addition, hypo-CM derived from MSCs improved restoration of ischemic heart, such as attenuating cell apoptosis and fibrosis, and ameliorating microvessel density. Based on our results, we propose a new therapeutic method for effective MI treatment using regulation of macrophage polarization. | Kim, Ran; Song, Byeong-Wook; Kim, Minji; Kim, Won Jung; Lee, Hee Won; Lee, Min Young; Kim, Jongmin; Chang, Woochul | Pusan Natl Univ, Coll Educ, Dept Biol Educ, Busan 46241, South Korea; Catholic Kwandong Univ, Coll Med, Dept Med Sci, Kangnung 25601, South Korea; Kyungpook Natl Univ, Coll Pharm, Dept Mol Physiol, Daegu 41566, South Korea; Sookmyung Womens Univ, Dept Life Syst, Seoul 04310, South Korea | Kim, Jinsoo/G-6348-2012; kim, minji/GRX-9996-2022; Song, Byeong-Wook/R-1077-2019 | 55859511600; 24345452200; 58365007200; 57204267974; 57204267330; 15119890400; 57007739600; 12797539700 | wchang1975@pusan.ac.kr; | BMB REPORTS | BMB REP | 1976-6696 | 1976-670X | 53 | 11 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY | 2020 | 4.778 | 33.1 | 0.86 | 2025-06-25 | 15 | 14 | Hypoxic conditioned medium; M2 macrophage; Macrophage polarization; Mesenchymal stem cells; Myocardial infarction therapy | POLARIZATION | Hypoxic conditioned medium; M2 macrophage; Macrophage polarization; Mesenchymal stem cells; Myocardial infarction therapy | Animals; Cell Differentiation; Cells, Cultured; Culture Media, Conditioned; Gene Expression; Gene Expression Regulation; Humans; Hypoxia; Inflammation; Macrophage Activation; Macrophages; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Myocardial Infarction; Transforming Growth Factor beta1; transforming growth factor beta1; animal; C57BL mouse; cell culture; cell differentiation; conditioned medium; gene expression; gene expression regulation; genetics; heart infarction; human; hypoxia; inflammation; macrophage; macrophage activation; male; mesenchymal stem cell; mesenchymal stem cell transplantation; metabolism; mouse; pathophysiology; pharmacology; physiology; procedures | English | 2020 | 2020-11-30 | 10.5483/bmbrep.2020.53.11.177 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Review | Sphingolipids in neuroinflammation: a potential target for diagnosis and therapy | Sphingolipids are ubiquitous building blocks of eukaryotic cell membranes that function as signaling molecules for regulating a diverse range of cellular processes, including cell proliferation, growth, survival, immune-cell trafficking, vascular and epithelial integrity, and inflammation. Recently, several studies have highlighted the pivotal role of sphingolipids in neuroinflammatory regulation. Sphingolipids have multiple functions, including induction of the expression of various inflammatory mediators and regulation of neuroinflammation by directly effecting the cells of the central nervous system. Accumulating evidence points to sphingolipid engagement in neuroinflammatory disorders, including Alzheimer's and Parkinson's diseases. Abnormal sphingolipid alterations, which involves an increase in ceramide and a decrease in sphingosine kinase, are observed during neuroinflammatory disease. These trends are observed early during disease development, and thus highlight the potential of sphingolipids as a new therapeutic and diagnostic target for neuroinflammatory diseases. | Lee, Ju Youn; Jin, Hee Kyung; Bae, Jae-Sung | Kyungpook Natl Univ, Alzheimers Dis Res Inst, Daegu 41566, South Korea; Kyungpook Natl Univ, Sch Med, Dept Physiol, Daegu 41944, South Korea; Kyungpook Natl Univ, Dept Biomed Sci, BK21 Plus KNU Biomed Convergence Program, Daegu 41944, South Korea; Kyungpook Natl Univ, Coll Vet Med, Dept Lab Anim Med, Daegu 41566, South Korea | Bae, Jae-sung/AAM-8663-2021; Kim, Young/T-8521-2019 | 56715493500; 8088145800; 35209510400 | hkjin@knu.ac.kr;jsbae@knu.ac.kr; | BMB REPORTS | BMB REP | 1976-6696 | 1976-670X | 53 | 1 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY | 2020 | 4.778 | 33.1 | 2.42 | 2025-06-25 | 52 | 52 | Alzheimer's disease; Ceramide; Neuroinflammation; Parkinson's disease; Sphingosine kinase; Sphingosine-1-phosphate | RESOLVING LIPID MEDIATORS; CNS INFLAMMATION; SPHINGOSINE 1-PHOSPHATE; CERAMIDE; MECHANISMS; RESOLUTION; SUPPRESSION; METABOLITES; ASPIRIN; BRAIN | Alzheimer's disease; Ceramide; Neuroinflammation; Parkinson's disease; Sphingosine kinase; Sphingosine-1-phosphate | Alzheimer Disease; Central Nervous System; Ceramides; Humans; Inflammation; Lysophospholipids; Microglia; Parkinson Disease; Phosphotransferases (Alcohol Group Acceptor); Signal Transduction; Sphingolipids; Sphingosine; ceramide; lysophospholipid; phosphotransferase; sphingolipid; sphingosine; sphingosine 1-phosphate; sphingosine kinase; Alzheimer disease; central nervous system; cytology; genetics; human; inflammation; metabolism; microglia; Parkinson disease; signal transduction | English | 2020 | 2020-01-31 | 10.5483/bmbrep.2020.53.1.278 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Change of groundwater inflow by cutoff grouting thickness and permeability coefficient | The groundwater during tunnel excavation not only affects the stability of the tunnel and constructability but also causes the subsidence of the upper ground due to the lowering of groundwater. Generally, the cutoff grouting is applied as a countermeasure to reduce the groundwater inflow during tunnel excavation, and the cutoff grouting is often applied in the range of plastic zone around the tunnel. However, grouting in the plastic zone is only appropriate for ground reinforcement purposes, and guidelines for the application range of cutoff grouting and the targeted permeability coefficient of the grouting zone are required. In this study, the relationship between groundwater inflow into tunnel and application range of cutoff grouting and permeability coefficient is proposed and compared with numerical analysis results. It was found that grouting with tunnel radius thickness is appropriate to reduce the groundwater inflows effectively. More than 90% reduction in groundwater inflow can be achieved when the annular area of the tunnel radius thickness is grouted with a permeability reduction ratio of 1/50 similar to 1/200. | Kim, Youngsang; Moon, Joon-Shik | Chonnam Natl Univ, Dept Civil Engn, Gwangju 61186, South Korea; Kyungpook Natl Univ, Dept Civil Engn, Daegu 41566, South Korea | Kim, Young-Sang/D-5083-2014 | 55699617000; 57149572000 | j.moon@knu.ac.kr; | GEOMECHANICS AND ENGINEERING | GEOMECH ENG | 2005-307X | 21 | 2 | SCIE | ENGINEERING, CIVIL;ENGINEERING, GEOLOGICAL | 2020 | 3.223 | 33.2 | 0.65 | 2025-06-25 | 13 | 14 | cutoff grouting; grouting zone; groundwater inflow; tunnel | Cutoff grouting; Groundwater inflow; Grouting zone; Tunnel | Concrete construction; Excavation; Groundwater; Grouting; Application range; Constructability; Ground reinforcement; Ground water inflow; Groundwater inflow into tunnel; Permeability reduction; Plastic zones; Tunnel excavation; Mortar | English | 2020 | 2020-04-25 | 10.12989/gae.2020.21.2.165 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Synthesis of Pd-Pt Ultrathin Assembled Nanosheets as Highly Efficient Electrocatalysts for Ethanol Oxidation | Control over composition and morphology of nanocrystals (NCs) is significant to develop advanced catalysts applicable to polymer electrolyte membrane fuel cells and further overcome the performance limitations. Here, we present a facile synthesis of Pd-Pt alloy ultrathin assembled nanosheets (UANs) by regulating the growth behavior of Pd-Pt nanostructures. Iodide ions supplied from KI play as capping agents for the {111} plane to promote 2-dimensional (2D) growth of Pd and Pt, and the optimal concentrations of cetyltrimethylammonium chloride and ascorbic acid result in the generation of Pd-Pt alloy UANs in high yield. The prepared Pd-Pt alloy UANs exhibited the remarkable enhancement of the catalytic activity and stability toward ethanol oxidation reaction compared to irregular-shaped Pd-Pt alloy NCs, commercial Pd/C, and commercial Pt/C. Our results confirm that the Pd-Pt alloy composition and ultrathin 2D morphology offer high accessible active sites and favorable electronic structure for enhancing electrocatalytic activity. | Han, Yeji; Kim, Jeonghyeon; Lee, Su-Un; Choi, Sang-Il; Hong, Jong Wook | Univ Ulsan, Dept Chem, Ulsan 44776, South Korea; Kyungpook Natl Univ, Dept Chem, Daegu 41566, South Korea; Kyungpook Natl Univ, Green Nano Mat Res Ctr, Daegu 41566, South Korea; Korea Res Inst Chem Technol, Chem & Proc Technol Div, 141 Gajeong Ro, Daejeon 34114, South Korea | Choi, Sang-Il/N-7571-2013; Choi, Sang-Il/AGR-1133-2022 | 57195486318; 57194560892; 55277969800; 56167600800; 57215820078 | sulee@krict.re.kr;sichoi@knu.ac.kr;jwhong@ulsan.ac.kr; | CHEMISTRY-AN ASIAN JOURNAL | CHEM-ASIAN J | 1861-4728 | 1861-471X | 15 | 8 | SCIE | CHEMISTRY, MULTIDISCIPLINARY | 2020 | 4.568 | 33.4 | 0.68 | 2025-06-25 | 16 | 17 | Pd-Pt bimetallic; Nanosheet assembly; Ethanol oxidation reaction | METAL NANOCRYSTALS; ALLOY NANOCRYSTALS; PALLADIUM; NANOSTRUCTURES; EVOLUTION; CATALYSIS; FACETS | Ethanol oxidation reaction; Nanosheet assembly; Pd−Pt bimetallic | Ascorbic acid; Binary alloys; Catalyst activity; Catalytic oxidation; Chlorine compounds; Electrocatalysts; Electronic structure; Ethanol; Morphology; Nanosheets; Oxidation; Palladium alloys; Platinum compounds; Polyelectrolytes; Proton exchange membrane fuel cells (PEMFC); Cetyltrimethylammonium chloride; Electrocatalytic activity; Ethanol oxidation; Ethanol oxidation reaction; Facile synthesis; Nanocrystal (NCs); Optimal concentration; Performance limitations; Platinum alloys | English | 2020 | 2020-04-17 | 10.1002/asia.202000041 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Nonlinear obstacle problems with double phase in the borderline case | In this paper we study a double phase problem with an irregular obstacle. The energy functional under consideration is characterized by the fact that both ellipticity and growth switch between a type of polynomial and a type of logarithm, which can be regarded as a borderline case of the double phase functional with (p,q)-growth. We obtain an optimal global Calderon-Zygmund type estimate for the obstacle problem with double phase in the borderline case. | Byun, Sun-Sig; Cho, Yumi; Oh, Jehan | Seoul Natl Univ, Dept Math Sci, Seoul 08826, South Korea; Seoul Natl Univ, Res Inst Math, Seoul 08826, South Korea; Kyungpook Natl Univ, Dept Math, Daegu 41566, South Korea | 8350569400; 55355811000; 56673305300 | jehan.oh@knu.ac.kr; | MATHEMATISCHE NACHRICHTEN | MATH NACHR | 0025-584X | 1522-2616 | 293 | 4 | SCIE | MATHEMATICS | 2020 | 1.228 | 33.5 | 0.69 | 2025-06-25 | 4 | 4 | BMO coefficient; Calderon-Zygmund estimate; double phase problem; obstacle problem; Reifenberg flat domain | ELLIPTIC-EQUATIONS; REGULARITY; GRADIENT; MINIMIZERS; FUNCTIONALS; INTEGRALS; EXISTENCE; CALCULUS; THEOREM; SPACES | 35B65; 35J87; BMO coefficient; Calderón–Zygmund estimate; double phase problem; obstacle problem; Reifenberg flat domain | English | 2020 | 2020-04 | 10.1002/mana.201800277 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article; Proceedings Paper | Characterization of Silver-Doped LiF Crystal Grown by Czochralski Technique for Dark Matter Search Application | In this article, the growth, luminescence, and scintillation properties of a silver-doped LiF crystal grown by the Czochralski technique are studied. The absorption spectrum of the crystal is measured at room temperature and optical energy bandgap of the crystal is calculated as similar to 5.2 eV. The luminescence and scintillation properties of the crystal are studied at different temperatures (10-550 K) under the excitations with X-ray, 266-nm laser, 280-nm light emitting diode (LED), and Sr-90 beta source. The crystal shows a violet emission (similar to 405 nm) under the excitation of a 280-nm LED source. The luminescence decay time of the crystal is measured from room temperature (300 K) to 10 K under the excitation of the 266-nm laser source. The decay time curves are fit with 2-exponential (300-200 K) and 3-exponential (175-10 K) decay functions. The shortest (27.2 mu s) and the longest decay time (42.8 mu s) of the crystal are obtained at 300 and 75 K, respectively. Thermoluminescence (TL) measurements were carried out from 10 to 300 K and 325 to 550 K in order to investigate the presence of trap centers. The different kinematic parameters such as order of kinematics, trap depth, and frequency factor are calculated for the observed TL peaks. The scintillation light yield of the crystal is measured with a continuous single photon counting technique using a Sr-90 beta source in the temperature range from 300 to 10 K. In this article, we will emphasize the potentiality of a Li-based crystal for dark matter search applications. | Pandey, Indra Raj; Daniel, D. Joseph; Kim, H. J.; Kim, Y. D.; Lee, M. H.; Khan, Sajid | Inst for Basic Sci Korea, Ctr Underground Phys, Daejeon 34126, South Korea; Kyungpook Natl Univ, Ctr High Energy Phys, Daegu 41566, South Korea; Kohat Univ Sci & Technol, Dept Phys, Kohat 26000, Pakistan | Kim, Hong Joo/AAE-1178-2022; khan, sajid/HGE-2406-2022; Lee, Moo/AAK-4266-2020 | 57188976474; 35319662800; 59051568100; 7410207253; 57198252980; 56266707900 | mhlee@ibs.re.kr; | IEEE TRANSACTIONS ON NUCLEAR SCIENCE | IEEE T NUCL SCI | 0018-9499 | 1558-1578 | 67 | 6 | SCIE | ENGINEERING, ELECTRICAL & ELECTRONIC;NUCLEAR SCIENCE & TECHNOLOGY | 2020 | 1.679 | 33.8 | 0 | 2025-06-25 | 0 | 0 | Continuous single photon counting; Czochralski technique; LiF crystal; luminescence and scintillation properties; thermoluminescence (TL) | LUMINESCENCE; LIMITS | Continuous single photon counting; Czochralski technique; LiF crystal; luminescence and scintillation properties; thermoluminescence (TL) | Absorption spectroscopy; Chromium compounds; Crystals; Dark Matter; Galaxies; Kinematics; Laser excitation; Light; Light emitting diodes; Lithium compounds; Particle beams; Scintillation; Silver; Thermoluminescence; Czochralski technique; Dark matter searches; Kinematic parameters; Luminescence decay time; Scintillation light yield; Scintillation properties; Single photon counting techniques; Temperature range; Fluorine compounds | English | 2020 | 2020-06 | 10.1109/tns.2020.2974517 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article; Proceedings Paper | Development of Tin-Based Single Crystal Scintillator for Double-Beta Decay Experiments | Sn-124 is one of the potential candidate isotopes for the study of 2 nu beta beta and 0 nu beta beta decay having a Q(beta beta) value of 2.228 MeV and natural isotopic abundance of 5.8%. Sn-124-loaded-liquid scintillator has been investigated for 2 nu beta beta and 0 nu beta beta decay search. Since 2 nu beta beta has not been experimentally observed from Sn-124 isotope, unlike some of the isotopes subject to double-beta decay (DBD), it is necessary to study this element. However, lower light yield, chemical instability, and lower Sn-loading capability are some of the limitations of the liquid and plastic scintillators. The current investigation has been carried out to develop a single crystal of tetraphenyltin (TPSn) for the 2 nu beta beta and 0 nu beta beta decay search experiments. The TPSn powder for crystal growing was purified by recrystallization. The single crystals were grown using two-zone vertical Bridgman and slow solvent-evaporation techniques. Purified powder, diphenyloxazole (PPO), 1, 4-bis(2-methylstyryl) benzene (bis-MSB), and anthracene-doped Bridgman-grown crystal and anthracene-doped solvent-evaporation grown crystals showed X-ray induced emission peaking at 475 nm. The anthracene-doped crystal grown by solvent evaporation method showed scintillation under alpha-particles excitation from Am-241 source. Two decay components, 16 ns with 68.7% and 132 ns with 31.3% relative contributions, were observed under alpha-particles excitation. This article suggests that after crystal growth optimization, TPSn can be a promising candidate for the DBD search of Sn-124. | Aryal, P.; Khan, A.; Kim, H. J.; Vuong, P. Q.; Kaewkhao, J.; Kothan, S.; Kaewjaeng, S. | Kyungpook Natl Univ, Dept Phys, Daegu 41566, South Korea; Nakhon Pathom Rajabhat Univ, Ctr Excellence Glass Technol & Mat Sci, Muang 73000, Nakhon Pathom, Thailand; Chiang Mai Univ, Fac Associated Med Sci, Dept Radiol Technol, Ctr Radiat Res & Med Imaging, Chiang Mai 50200, Thailand | ; Khan, Arshad/ABB-1566-2021; Kim, Hong Joo/AAE-1178-2022 | 57196222852; 56017063700; 59051568100; 57207618553; 23974520300; 6507017165; 55871868200 | hongjoo@knu.ac.kr; | IEEE TRANSACTIONS ON NUCLEAR SCIENCE | IEEE T NUCL SCI | 0018-9499 | 1558-1578 | 67 | 6 | SCIE | ENGINEERING, ELECTRICAL & ELECTRONIC;NUCLEAR SCIENCE & TECHNOLOGY | 2020 | 1.679 | 33.8 | 0 | 2025-06-25 | 0 | 0 | Double-beta decay (DBD); single crystal scintillator; tetraphenyltin (TPSn) | RESOLUTION X-RAY; LIQUID SCINTILLATOR; SEARCH; BENZIMIDAZOLE | Double-beta decay (DBD); single crystal scintillator; tetraphenyltin (TPSn) | Alpha particles; Anthracene; Evaporation; Isotopes; Purification; Scintillation counters; Solvents; Tin; Bridgman grown crystals; Chemical instability; Crystal scintillators; Growth optimization; Plastic scintillator; Relative contribution; Solvent evaporation method; Solvent evaporation techniques; Single crystals | English | 2020 | 2020-06 | 10.1109/tns.2020.2978903 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article; Proceedings Paper | Scintillation Properties of Tetrafluoroaluminate Crystal | In this article, single crystals of a new nonhygroscopic scintillating material of tetrafluoroaluminate (TlAlF4) were grown using the Bridgman-Stockbarger technique. The diffraction pattern obtained from powder X-ray diffraction was found to be in good agreement with the reference data. The X-ray-induced luminescence measurements of the grown crystal sample exhibit a very strong intrinsic emission band in the wavelength range from 300 to 450 nm, with a peak maximum at 390 nm. Scintillation properties, such as pulse height spectra and decay time of the grown crystals, were investigated using gamma-rays from the Cs-137 radiation source. The scintillation light yield was found to be similar to 11 800 ph/MeV. At room temperature, the measured decay time profile was fitted with three exponential functions; the result showed a fast component of 194 ns (13.1%), a medium component of 992 ns (84.6%), and a slow component of 3.5 mu s (2.3%). Trap centers were studied using the results obtained from thermally stimulated luminescence. The temperature dependence of the scintillation light yield and decay time was also studied. The results showed that TlAlF4 is a promising scintillator crystal, and thus, a potential candidate for X-ray and gamma-ray detection. | Daniel, D. Joseph; Khan, Arshad; Tyagi, Mohit; Kim, H. J. | Kyungpook Natl Univ, Dept Phys, Daegu 41566, South Korea; Bhabha Atom Res Ctr, Tech Phys Div, Mumbai 400085, Maharashtra, India | Khan, Arshad/ABB-1566-2021; Kim, Hong Joo/AAE-1178-2022; Tyagi, Mohit/T-2735-2019 | 35319662800; 56017063700; 21234397100; 59051568100 | hongjoo@knu.ac.kr; | IEEE TRANSACTIONS ON NUCLEAR SCIENCE | IEEE T NUCL SCI | 0018-9499 | 1558-1578 | 67 | 6 | SCIE | ENGINEERING, ELECTRICAL & ELECTRONIC;NUCLEAR SCIENCE & TECHNOLOGY | 2020 | 1.679 | 33.8 | 0.6 | 2025-06-25 | 5 | 8 | Crystals; fluorine compounds; luminescence; scintillators | HALIDE SCINTILLATOR; CURVE DECONVOLUTION; PERFORMANCE; LUMINESCENCE; RESOLUTION; THALLIUM; CE3+ | Crystals; fluorine compounds; luminescence; scintillators | Aluminum compounds; Exponential functions; Fluorine compounds; Light; Scintillation; Temperature distribution; Bridgman-Stockbarger Techniques; Luminescence measurements; Powder X ray diffraction; Scintillation light yield; Scintillation properties; Temperature dependence; Thermally stimulated luminescence; X-ray and gamma-ray detections; Gamma rays | English | 2020 | 2020-06 | 10.1109/tns.2020.2986004 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Silver-Doped LiI Crystal: A Sensitive Thermal Neutron Detector With Pulse Shape Discrimination | Single crystals of LiI with different Ag concentrations are investigated for dual-mode thermal neutron and gamma-ray detection. The crystal growth and scintillation properties of these crystals have been studied and reported in our recent communication. On the other hand, a LiI crystal with Eu2+ dopant was used for thermal neutron detection using pulse height discrimination (PHD). However, the LiI:Eu crystal has a disadvantage in the case of high-energetic gamma background which is usually accompanied with neutrons in practical applications. In this case, LiI:Ag might be a better option since it can distinguish neutrons and gamma-signals by both pulse shape discrimination (PSD) and PHD. The PSD capability of LiI:Ag was checked for alpha and gamma signals. The figure-of-merit (FOM) value was estimated to be 1.7 using the charge comparison method. LiI:Ag crystals were encapsulated for neutron measurements using Cf-252 and Am-Be sources. The best FOM value was obtained to be 1.5 for the LiI:0.1%Ag crystal. The current investigation reveals that LiI:Ag can be a promising candidate for the dual-mode thermal neutron and gamma-ray spectroscopy applications. | Vuong, Phan Quoc; Kim, H. J.; Khan, Arshad; Khan, Sajid; Kim, S. H.; Park, Hyeonseo; Kim, Jungho | Kyungpook Natl Univ, Dept Phys, Daegu 41566, South Korea; Kohat Univ Sci & Technol, Dept Phys, Kohat 26000, Pakistan; Cheongju Univ, Dept Radiol Sci, Cheongju 28503, South Korea; Korea Res Inst Stand & Sci KRISS, Daejeon 305340, South Korea | khan, sajid/HGE-2406-2022; Kim, Hong Joo/AAE-1178-2022; Khan, Arshad/ABB-1566-2021 | 57207618553; 59051568100; 56017063700; 56266707900; 36165569900; 57216599536; 56784564000 | hongjoo@knu.ac.kr; | IEEE TRANSACTIONS ON NUCLEAR SCIENCE | IEEE T NUCL SCI | 0018-9499 | 1558-1578 | 67 | 10 | SCIE | ENGINEERING, ELECTRICAL & ELECTRONIC;NUCLEAR SCIENCE & TECHNOLOGY | 2020 | 1.679 | 33.8 | 0.77 | 2025-06-25 | 13 | 14 | LiI(Ag) crystals; neutron detector; pulse shape discrimination (PSD); scintillator | LITHIUM IODIDE; INORGANIC SCINTILLATORS; SPECTROMETRY; ACTIVATION | LiI(Ag) crystals; neutron detector; pulse shape discrimination (PSD); scintillator | Beryllium alloys; Beryllium metallography; Chromium compounds; Europium compounds; Gamma rays; Neutron detectors; Neutrons; Silver; Silver metallography; Charge comparison methods; Figure of merit (FOM); Neutron measurements; Pulse shape discrimination; Scintillation properties; Spectroscopy applications; Thermal neutron detectors; Thermal-neutron detection; Lithium compounds | English | 2020 | 2020-10 | 10.1109/tns.2020.3004936 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Methods of weighted moments for the relay feedback autotuning of conservative PI controllers | First order plus time delay (FOPTD) models obtained from the cyclic steady state of the relay feedback oscillations can suffer from poor performances for some processes such as first and second order processes with fast parasitic dynamics. Poor FOPTD models are due to high frequency oscillations that activate parasitic dynamics. Dynamic elements such as hysteresis and integrator added in the feedback loop can reduce the oscillation frequencies but they increase the experimental times. Here, to relieve these problems without increasing the experimental time and computational complexity, relay feedback auto-tuning methods that apply the method of weighted moments to relay feedback transients are proposed. The proposed methods use the same relay feedback tests as the conventional relay feedback methods and are simple to use computationally, providing conservative PI controllers for all the test batch processes and the above first and second order processes with fast parasitic dynamics. (C) 2020 Published by Elsevier Ltd. | Lee, Jietae; Lee, Friedrich Y.; Baldea, Michael; Edgar, Thomas F. | Kyungpook Natl Univ, Dept Chem Engn, Daegu 41566, South Korea; Univ Texas Austin, Dept Chem Engn, Austin, TX 78712 USA | Lee, Si/ABH-1408-2020 | 7601455194; 57211367408; 7801529672; 35569277000 | jtlee@knu.ac.kr; | COMPUTERS & CHEMICAL ENGINEERING | COMPUT CHEM ENG | 0098-1354 | 1873-4375 | 136 | SCIE | COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS;ENGINEERING, CHEMICAL | 2020 | 3.845 | 33.9 | 0.13 | 2025-06-25 | 4 | 4 | Relay feedback autotuning; Method of weighted moments; Variable transformations; FOPTD model; PID controllers | TUNING RULES; IDENTIFICATION; RESPONSES | FOPTD model; Method of weighted moments; PID controllers; Relay feedback autotuning; Variable transformations | Batch data processing; Controllers; Dynamics; Relay control systems; Three term control systems; Autotuning; FOPTD model; Method of weighted moments; PID controllers; Variable transformation; Feedback | English | 2020 | 2020-05-08 | 10.1016/j.compchemeng.2020.106797 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | Article | A facile and rapid fabrication of multifunctional color-tuned titanium | In this article, a strategy for the fabrication of color-tuned titanium using a torch was developed. The torch was used to manufacture a layer of titanium dioxide on titanium substrates. The reaction time and requirements were reduced compared to the anodization process. Various colors appeared depending on the time of torch heating, and this torched-titanium substrate was treated with octadecyltriethoxylsilane (ODTS) to gain superhydrophobic properties for self-cleaning. Scanning Electron Microscope (SEM), Raman spectroscopy, and Atomic Force Microscope (AFM) were used for surface analysis. Besides, the mechanical and ODTS stability of the surface were evaluated through a cross-cut adhesion tape test and water contact angle measurement, proving that the torch is a suitable fabrication process for multifunctional color-tuned titanium. © 2020 by the author. Licensee MDPI, Basel, Switzerland. | Choi, Jihun; Park, Soyeon; Jeon, Sangmin; Yim, Changyong | Department of Chemical Engineering, Pohang University of Science and Technology (POSTECH), Pohang, 37674, South Korea; School of Nano and Materials Science and Engineering, Kyungpook National University (KNU), Sangju, 37224, South Korea; Department of Chemical Engineering, Pohang University of Science and Technology (POSTECH), Pohang, 37674, South Korea; School of Nano and Materials Science and Engineering, Kyungpook National University (KNU), Sangju, 37224, South Korea, Department of Advanced Science and Technology Convergence, Kyungpook National University (KNU), Sangju, 37224, South Korea | 57218190310; 57220120941; 7203005726; 36877182000 | cy.yim@knu.ac.kr; | Crystals | CRYSTALS | 2073-4352 | 2073-4352 | 10 | 11 | SCIE | CRYSTALLOGRAPHY;MATERIALS SCIENCE, MULTIDISCIPLINARY | 2020 | 2.589 | 34.0 | 0.07 | 2025-06-25 | 2 | Color-tuned titanium; Electropolishing; Sandpaper; Superhydrophobicity; Titanium oxide; Torch | English | Final | 2020 | 10.3390/cryst10111065 | 바로가기 | 바로가기 | 바로가기 | ||||||||
| ○ | ○ | Article | Cisplatin nephrotoxicity is induced via poly(ADP-ribose) polymerase activation in adult zebrafish and mice | Cisplatin is a well-known chemotherapy medication used to treat numerous cancers. However, treatment with cisplatin in cancer therapy has major side effects, such as nephrotoxic acute kidney injury. Adult vertebrate kidneys are commonly used as models of cisplatin-induced nephrotoxic acute kidney injury. Embryonic zebrafish kidney is more simplified and is composed simply of two nephrons and thus is an excellent model for the investigation of cisplatin nephrotoxicity. Here, we developed a novel model to induce cisplatin nephrotoxicity in adult zebrafish and demonstrated that intraperitoneal injection of cisplatin caused a decline in kidney proximal tubular function based on fluorescein-labeled dextran uptake and alkaline phosphatase staining. We also showed that cisplatin induced histological injury of the kidney tubules, quantified by tubular injury scores on the periodic acid-Schiff-stained kidney sections. As shown in a mouse model of cisplatin-induced nephrotoxicity, the activation of poly(ADP-ribose) polymerase (PARP), an enzyme implicated in cisplatin-induced cell death. was markedly increased after cisplatin injection in adult zebrafish. Furthermore, pharmacological inhibition of PARP using a specific PARP inhibitor PJ 34 hydrochloride (PJ34) or 3-aminobenzamide ameliorated kidney proximal tubular functional and histological damages in cisplatin-injected adult zebrafish kidneys. Administration of a combination of PARP inhibitors PJ34 and 3-aminobenzamide additively protected renal function and histology in zebrafish and mouse models of cisplatin nephrotoxicity. In conclusion. these data suggest that adult zebrafish are not only suitable for drug screening and genetic manipulation but also useful as a simplified but powerful model to study the pathophysiology of cisplatin nephrotoxicity and establish new therapies for treating human kidney diseases. | Kim, Myoung-Jin; Moon, Daeun; Jung, Sumi; Lee, Jehee; Kim, Jinu | Jeju Natl Univ, Dept Marine Life Sci, Jeju, South Korea; Jeju Natl Univ, Fish Vaccine Res Ctr, Jeju, South Korea; Kyungpook Natl Univ, Sch Appl Biosci, Daegu, South Korea; Jeju Natl Univ, Interdisciplinary Grad Program Adv Convergence Te, Jeju, South Korea; Jeju Natl Univ, Dept Anat, Sch Med, Jeju, Self Governing, South Korea | Lee, Jehee/AAS-3229-2021 | 57191626729; 57211064581; 57200687597; 7601467203; 16316045800 | jehee@jejunu.ac.kr;jinu.kim@jejunu.ac.kr; | AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY | AM J PHYSIOL-REG I | 0363-6119 | 1522-1490 | 318 | 5 | SCIE | PHYSIOLOGY | 2020 | 3.619 | 34.0 | 0.88 | 2025-06-25 | 15 | 19 | cisplatin; PARP; proximal tubule; toxicity; zebrafish | NECROTIC CELL-DEATH; ACUTE-RENAL-FAILURE; REPERFUSION INJURY; KIDNEY INJURY; STEM-CELLS; MECHANISMS; SPERMIDINE; ISCHEMIA; NECROSIS | Cisplatin; PARP; Proximal tubule; Toxicity; Zebrafish | Animals; Benzamides; Cisplatin; Disease Models, Animal; DNA Damage; Kidney Diseases; Kidney Tubules; Male; Mice, Inbred C57BL; Phenanthrenes; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Signal Transduction; Zebrafish; Zebrafish Proteins; 3 aminobenzamide; alkaline phosphatase; cisplatin; fluorescein isothiocyanate dextran; n (5,6 dihydro 6 oxo 2 phenanthridinyl) 2 dimethylaminoacetamide; nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase; 3-aminobenzamide; benzamide derivative; cisplatin; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride; nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase; nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase inhibitor; phenanthrene derivative; zebrafish protein; adult; animal cell; animal experiment; animal model; animal tissue; Article; cell death; controlled study; drug screening; enzyme activation; enzyme inhibition; genetic manipulation; histology; human; kidney function; kidney proximal tubule; kidney tubule damage; male; mouse; nephrotoxicity; nonhuman; pathophysiology; periodic acid Schiff stain; priority journal; renal protection; zebra fish; animal; C57BL mouse; disease model; DNA damage; drug effect; enzymology; kidney disease; kidney tubule; metabolism; pathology; signal transduction | English | 2020 | 2020-05 | 10.1152/ajpregu.00130.2019 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Effects of Experimental Configuration on the Morphology of Two-Dimensional ZnO Nanostructures Synthesized by Thermal Chemical-Vapor Deposition | Using two experimental configurations, self-assembled zinc oxide (ZnO) nanostructures including nanoplates, nanosaws, and nanobelts were synthesized by thermal chemical-vapor deposition (CVD), and their morphological properties were investigated. ZnO nanostructures grown on Au-coated Si substrates in a parallel setup revealed highly defined ZnO nanoplates and branched nanowires. ZnO nanostructures grown in a perpendicular setup using Si substrates with and without the Au catalyst exhibited vertically oriented ZnO nanosaws and randomly aligned nanobelts, respectively. In the thermal CVD method, experiment conditions such as oxygen-flow rate, growth temperature, and catalyst, and experimental configurations (i.e., parallel and perpendicular setups) were important parameters to control the morphologies of two-dimensional ZnO nanostructures showing platelike, sawlike, and beltlike shapes. | Choi, Seok Cheol; Lee, Do Kyung; Sohn, Sang Ho | LG Elect, Dept Proc Dev, Gumi 3938, Gyeongsangbuk D, South Korea; Daegu Catholic Univ, Sch Adv Mat Sci & Chem Engn, Gyongsan 38430, Gyeongsangbuk D, South Korea; Kyungpook Natl Univ, Dept Phys, Daegu 41566, South Korea | 59102851900; 55941000700; 7101646506 | jomi119@hanmail.net;dokyung@cu.ac.kr;shsohn@knu.ac.kr; | CRYSTALS | CRYSTALS | 2073-4352 | 10 | 6 | SCIE | CRYSTALLOGRAPHY;MATERIALS SCIENCE, MULTIDISCIPLINARY | 2020 | 2.589 | 34.0 | 0.75 | 2025-06-25 | 13 | 15 | experimental configuration; ZnO nanoplates; ZnO nanosaws; ZnO nanobelts; thermal chemical-vapor deposition; two-dimensional nanostructures | NANOWIRES; GROWTH; PHOTOLUMINESCENCE; FABRICATION; NANOBELTS; MECHANISM; NANORODS; ARRAYS | Experimental configuration; Thermal chemical-vapor deposition; Two-dimensional nanostructures; ZnO nanobelts; ZnO nanoplates; ZnO nanosaws | English | 2020 | 2020-06 | 10.3390/cryst10060517 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Efficient Design Method for Plasmonic Filter for Tuning Spectral Selectivity | Nano-structure-based color technologies have been reported as alternatives for conventional pigment- or dye-based color filters due to their simple design methods and durable characteristics. Since structure-based optical resonances accompany multiple resonance modes, spectral selectivity could be degraded. In this work, a simple and effective design of a plasmonic color filter that combines the plasmonic filter with one-dimensional photonic crystals. The introduced photonic crystal provides a photonic band gap, and it helps in suppressing the undesirable transmission peaks of the plasmonic color filter that originates from higher order resonance modes. Finally, the proposed design achieves high color purity. In addition, the simplicity of the design makes it both suitable for large-area fabrication and cost effective. This work is expected to provide a practical alternative to traditional color filters. | Do, Yun Seon | Kyungpook Natl Univ, Coll IT Engn, Sch Elect Engn, Daegu 41566, South Korea | 24338060500 | yuns.do@knu.ac.kr; | CRYSTALS | CRYSTALS | 2073-4352 | 10 | 6 | SCIE | CRYSTALLOGRAPHY;MATERIALS SCIENCE, MULTIDISCIPLINARY | 2020 | 2.589 | 34.0 | 0.15 | 2025-06-25 | 1 | 2 | plasmonic filter; photonic bandgap; spectral selectivity | COLOR FILTERS; OPTICAL-TRANSMISSION; CRYSTAL-STRUCTURES; HOLE ARRAYS; CROSS-TALK; BAND | Photonic bandgap; Plasmonic filter; Spectral selectivity | English | 2020 | 2020-06 | 10.3390/cryst10060531 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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