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WoS SCOPUS Document Type Document Title Abstract Authors Affiliation ResearcherID (WoS) AuthorsID (SCOPUS) Author Email(s) Journal Name JCR Abbreviation ISSN eISSN Volume Issue WoS Edition WoS Category JCR Year IF JCR (%) FWCI FWCI Update Date WoS Citation SCOPUS Citation Keywords (WoS) KeywordsPlus (WoS) Keywords (SCOPUS) KeywordsPlus (SCOPUS) Language Publication Stage Publication Year Publication Date DOI JCR Link DOI Link WOS Link SCOPUS Link
Article Expression of insulinoma-associated protein 1 (INSM1) in gastric neuroendocrine and non-neuroendocrine neoplasms Aims Insulinoma-associated protein 1 (INSM1) is a recently added nuclear marker for neuroendocrine differentiation. However, INSM1 expression in gastric neuroendocrine and non-neuroendocrine neoplasms has not been thoroughly investigated. Methods We examined INSM1 expression in 72 gastric tumors, including 22 gastric neuroendocrine tumors and 50 gastric non-neuroendocrine neoplasms. Synaptophysin and chromogranin immunostaining were also performed for all cases. Results For gastric neuroendocrine neoplasms, INSM1 immunostaining demonstrated excellent sensitivity (21/22, 95.5%), comparable to synaptophysin (22/22, 100.0%), but had lower specificity (32/50, 64.0%) compared with traditional neuroendocrine markers (synaptophysin (36/50, 72.0%) and chromogranin (42/50, 84.0%)). However, decreased expression of INSM1, measured by H-score, was frequently found among neuroendocrine carcinoma cases. Gastric non-neuroendocrine neoplasms frequently exhibited INSM1 positivity (18/50, 36.0%); however, in most cases (16/18, 88.9%), staining was focal (involving < 10% of tumor cells). Tumor histologic subtype and grade may be associated with INSM1 expression. Conclusions INSM1 nuclear positivity in gastric neoplasms should be interpreted with caution. INSM1 should not be used as a stand-alone marker for determining neuroendocrine differentiation in gastric tumors. Histologic evaluation with concurrent use of traditional neuroendocrine markers is warranted to accurately demonstrate neuroendocrine differentiation and minimize false positivity and false negativity. Kim, Sujeong; Seo, Jisu; Shin, Youjung; Kim, Moonsik Kyungpook Natl Univ, Sch Med, Daegu, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Sch Med, Dept Pathol, Daegu 41405, South Korea 59894071500; 59893884600; 59893699900; 57195918515 teiroa83@knu.ac.kr; DISCOVER ONCOLOGY DISCOV ONCOL 2730-6011 16 1 SCIE ENDOCRINOLOGY & METABOLISM;ONCOLOGY 2024 2.9 46.8 0 2025-06-11 0 0 INSM1; Neuroendocrine neoplasm; Stomach cancer; Immunohistochemistry DIFFERENTIATION; MARKER; IA-1 Immunohistochemistry; INSM1; Neuroendocrine neoplasm; Stomach cancer chromogranin; insulinoma associated protein 1; peptides and proteins; synaptophysin; unclassified drug; adult; aged; area under the curve; Article; cancer prognosis; cancer staging; cohort analysis; controlled study; diagnostic test accuracy study; false negative result; false positive result; female; gastric neuroendocrine tumor; histology; human; human tissue; immunohistochemistry; male; neuroendocrine carcinoma; receiver operating characteristic; retrospective study; stomach cancer English 2025 2025-05-13 10.1007/s12672-025-02576-2 바로가기 바로가기 바로가기 바로가기
Article Impact of Modifying Lazertinib Doses on Effectiveness and Safety in Patients With EGFR-Positive Advanced Lung Cancer: A Multicenter, Prospective Observational Cohort Study IntroductionThe clinical application of lazertinib, a third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, has extended to the treatment of EGFR-mutant non-small-cell lung cancer (NSCLC); however, the effects of its dose modification on its efficacy and safety have not yet been adequately established.MethodsThis prospective, multicenter, observational cohort study aims to evaluate the clinical implications of adjusting the lazertinib dose. Patients will be categorized into two groups based on the lazertinib dose administered during the initial 12 weeks of treatment in routine clinical practice: 160 and 240 mg groups. The primary endpoints are progression-free survival in the 160 mg group and identifying risk factors associated with dose modification during the 12-week period.DiscussionThe findings from the present study will provide real-world insights into the clinical factors leading to lazertinib dose adjustments and deepen our understanding of the efficacy and safety of lazertinib in patients with NSCLC. Our research will contribute toward optimizing medical strategies for NSCLC treatment and aid clinicians in making accurate clinical decisions regarding dose modifications in routine practice. Kim, Mi-Hyun; Lee, Min Ki; Park, Ji Eun; Park, Sun Hyo; Jang, Tae Won; Jung, Chi Young; Kim, Insu; Yoon, Seong Hoon; Ahn, June Hong; Lee, Hyun-Kyung; Park, Jin Han; Choi, Sun Ha; Eom, Jung Seop Pusan Natl Univ, Sch Med, Dept Internal Med, Busan, South Korea; Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu, South Korea; Keimyung Univ, Sch Med, Div Pulmonol, Dongsan Hosp,Resp Ctr, Daegu, South Korea; Kosin Univ, Med Coll, Dept Internal Med, Busan, South Korea; Catholic Univ Daegu, Sch Med, Dept Internal Med, Daegu, South Korea; Dong A Univ, Coll Med, Dept Internal Med, Busan, South Korea; Pusan Natl Univ, Yangsan Hosp, Dept Internal Med, Yangsan, South Korea; Yeungnam Univ, Coll Med, Dept Internal Med, Daegu, South Korea; Inje Univ, Coll Med, Dept Internal Med, Div Pulm Allergy & Crit Care Med,Busan Paik Hosp, Busan, South Korea; Inje Univ, Haeundae Paik Hosp, Dept Internal Med, Div Pulmonol & Crit Care Med,Coll Med, Busan, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Sch Med, Dept Internal Med, Daegu, South Korea Ahn, June/AAB-3093-2019 59910489600; 59910175000; 57195437358; 57191525804; 59909552500; 57223991305; 57191965736; 55479240500; 56645445800; 59910489700; 57043777100; 57199723585; 57201262394 ejspulm@gmail.com; THORACIC CANCER THORAC CANCER 1759-7706 1759-7714 16 10 SCIE ONCOLOGY;RESPIRATORY SYSTEM 2024 2.3 46.8 0 2025-06-11 0 0 dose modification; epidermal growth factor receptor; lazertinib; treatment outcome dose modification; epidermal growth factor receptor; lazertinib; treatment outcome Aged; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Female; Humans; Lung Neoplasms; Male; Middle Aged; Prospective Studies; Protein Kinase Inhibitors; epidermal growth factor receptor; lazertinib; EGFR protein, human; epidermal growth factor receptor; protein kinase inhibitor; adult; advanced cancer; Article; brain metastasis; cancer radiotherapy; cancer staging; cancer surgery; clinical practice; cohort analysis; computer assisted tomography; controlled study; disease control; drug efficacy; drug safety; ECOG Performance Status; female; gene deletion; gene mutation; human; lung cancer; major clinical study; male; multicenter study; non small cell lung cancer; observational study; proportional hazards model; prospective study; risk factor; smoking; substitution mutation; tumor shrinkage; aged; clinical trial; drug therapy; genetics; lung tumor; middle aged; non small cell lung cancer; pathology English 2025 2025-05 10.1111/1759-7714.70083 바로가기 바로가기 바로가기 바로가기
Article Impact of tumor-to-nipple distance on outcomes in robotic nipple-sparing mastectomy and reconstruction Background Nipple-sparing mastectomy (NSM) has become a preferred surgical option for breast cancer patients due to its oncologic safety and aesthetic benefits. Robotic NSM (RNSM) offers enhanced precision and minimally invasive access, yet its feasibility in cases with a tumor-to-nipple distance (TND) 1 cm and conventional NSM (CNSM) in patients with TND 1 cm, RNSM and TND 1 cm RNSM groups. Similarly, no significant differences were found in oncologic or surgical outcomes between RNSM and CNSM in patients with TND 1 cm. These findings suggest that TND <= 1 cm should not be a contraindication for RNSM. Further prospective studies with long-term follow-up are necessary to validate these results. Moon, Joon Suk; Lee, Young Jin; Yoo, Tae Kyung; Kim, Jisun; Chung, Il Yong; Ko, Beom Seok; Kim, Hee Jeong; Lee, Jong Won; Son, Byung Ho; Lee, Sae Byul Kyungpook Natl Univ, Chilgok Hosp, Sch Med, Dept Surg, Daegu, South Korea; Univ Ulsan, Asan Med Ctr, Dept Surg, Div Breast Surg,Coll Med, 88 Olymp Ro 43 Gil, Seoul 05505, South Korea 55172800300; 57219667204; 59907829700; 55913243600; 59707757100; 59707524000; 57205135299; 59676912300; 59677470000; 59676348000 newstar153@hanmail.net; DISCOVER ONCOLOGY DISCOV ONCOL 2730-6011 16 1 SCIE ENDOCRINOLOGY & METABOLISM;ONCOLOGY 2024 2.9 46.8 0 2025-06-11 0 0 Nipple-sparing mastectomy; Robotic nipple-sparing mastectomy; Conventional nipple-sparing mastectomy; Tumor-to-nipple distance INVOLVEMENT; SYSTEM Conventional nipple-sparing mastectomy; Nipple-sparing mastectomy; Robotic nipple-sparing mastectomy; Tumor-to-nipple distance adult; Article; biopsy; body mass; breast areola; breast cancer; breast reconstruction; cancer patient; cancer staging; cancer surgery; clinical outcome; cohort analysis; controlled study; female; human; human tissue; incidence; major clinical study; mammography; middle aged; neoadjuvant chemotherapy; nipple areolar complex necrosis; nipple-sparing mastectomy; nuclear magnetic resonance imaging; oncological parameters; postoperative complication; propensity score; prospective study; retrospective study; robotic nipple sparing mastectomy; subareolar resection margin; surgical margin; tumor to nipple distance; ultrasound English 2025 2025-05-23 10.1007/s12672-025-02736-4 바로가기 바로가기 바로가기 바로가기
Article Study Protocol of the Korean EGFR Registry: A Multicenter Prospective and Retrospective Cohort Study in Nonsmall Cell Lung Cancer Patients With EGFR Mutation IntroductionThe provision of treatment for epidermal growth factor receptor (EGFR)-mutated nonsmall cell lung cancer (NSCLC) patients has increased in Korea. However, multicenter studies on the clinicopathologic dataset and treatment outcomes, using a large-scale dataset, have not been conducted. The current study is a prospective and retrospective multicenter observational cohort study that registers all stages of EGFR-mutated NSCLC patients.MethodsThe Korean EGFR Registry was designed to enroll 2000 patients with all stages of EGFR-mutated NSCLC from 40 university hospitals across Korea. This study, encompassing both retrospective and prospective cohorts, aims to analyze clinical characteristics, treatment modalities, and outcomes in these patients. Data collection will include patient demographics, smoking history, quality of life assessments, pathological data, and treatment outcomes, with follow-up until December 2026. The primary endpoint is disease-free survival in patients who have undergone radical therapy (surgery and radiotherapy) or progression-free survival in those receiving targeted therapy (first, second, and subsequent lines), chemotherapy (first and subsequent lines), combination therapy, and palliative/maintenance therapy according to stages of EGFR-mutated NSCLC. The study will explore the diagnostic methods for EGFR mutations, clinical outcomes based on treatment modalities, and metastatic patterns in EGFR-mutated NSCLC patients. Moreover, it will investigate various aspects, including the safety and efficacy of a new third-generation EGFR tyrosine kinase inhibitor (TKI), lazertinib, approved for both first- and second-line treatments.DiscussionThis study is expected to provide valuable insights into the epidemiology, risk factors, progression, and treatment outcomes of EGFR-mutated NSCLC in Korea. The Korean EGFR Registry will contribute significantly to the understanding of the complex dynamics of EGFR-mutated NSCLC, aiding in the development of more effective and personalized treatment strategies. Yeo, Chang Dong; Park, Dong Won; Yoon, Seong Hoon; Kim, Eun Young; Lee, Jeong Eun; Lee, Shin Yup; Choi, Chang-Min; Oh, In-Jae; Kim, Do Jin; Ryu, Jeong Seon; Lee, Jae Cheol; Kim, Young-Chul; Jang, Tae Won; Lee, Kye Young; Jang, Seung Hun; Kim, Seung Joon Catholic Univ Korea, Eunpyeong St Marys Hosp, Coll Med, Div Pulm Crit Care & Sleep Med,Dept Internal Med, Seoul, South Korea; Hanyang Univ, Hanyang Med Ctr, Dept Internal Med, Div Pulm Med & Allergy,Coll Med, Seoul, South Korea; Pusan Natl Univ, Yangsan Hosp, Dept Internal Med, Yangsan, South Korea; Yonsei Univ, Severance Hosp, Dept Internal Med, Div Pulmonol,Coll Med, Seoul, South Korea; Chungnam Natl Univ, Coll Med, Dept Internal Med, Div Pulmonol, Daejeon, South Korea; Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu, South Korea; Univ Ulsan, Coll Med, Asan Med Ctr, Div Pulm & Crit Care Med, Seoul, South Korea; Chonnam Natl Univ, Med Sch, Dept Internal Med, Hwasun, South Korea; Hwasun Hosp, Hwasun, South Korea; Soonchunhyang Univ, Coll Med, Bucheon Hosp, Div Resp Allergy,Dept Internal Med, Bucheon, South Korea; Inha Univ Hosp, Dept Internal Med, Incheon, South Korea; Univ Ulsan, Coll Med, Asan Med Ctr, Dept Oncol, Seoul, South Korea; Kosin Univ, Med Coll, Dept Internal Med, Pusan, South Korea; Konkuk Univ, Sch Med, Dept Pulm Med, Seoul, South Korea; Hallym Univ, Sacred Heart Hosp, Dept Internal Med, Div Pulm Allergy & Crit Care Med,Coll Med, Anyang, South Korea; Catholic Univ Korea, Seoul St Marys Hosp, Dept Internal Med, Div Pulmonol, Seoul, South Korea Lee, Jeong Eun/R-8689-2019; Kim, Eun-young/AAI-8613-2020; Kim, Yong-Joo/AAK-1840-2021; PARK, DONG WON/V-7939-2017 55233857000; 55746540800; 55479240500; 57361264500; 57209104622; 49863712700; 14024046800; 58754601500; 55742878200; 7401868634; 24825051600; 35201246200; 7102426031; 8720534800; 7402219050; 59716109700; 57043630300; 57203375020; 57217473793; 57208400366; 57191525804; 59505921500; 56734650000; 57223991305; 26323727500; 57835046800; 58802153100; 57221608757; 57225930594; 54898316800; 58304571900; 56645445800; 57218205687; 7406950928; 57484738300; 57196170749; 56563350500; 57214084476; 59506992100; 56561312800; 57188733427; 57193095178; 57203056002; 57043777100; 7102840401; 57203643076; 7005044020 chestor@hallym.or.kr; cmcksj@catholic.ac.kr; CLINICAL RESPIRATORY JOURNAL CLIN RESPIR J 1752-6981 1752-699X 19 1 SCIE RESPIRATORY SYSTEM 2024 2.3 46.8 0 2025-05-07 0 0 EGFR; Korean; lung cancer; registry study RESISTANCE EGFR; Korean; lung cancer; registry study Adult; Aged; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Female; Humans; Lung Neoplasms; Male; Middle Aged; Mutation; Prospective Studies; Quality of Life; Registries; Republic of Korea; Retrospective Studies; epidermal growth factor receptor; lazertinib; EGFR protein, human; epidermal growth factor receptor; adult; Article; cancer chemotherapy; cancer growth; cancer palliative therapy; cancer radiotherapy; cancer staging; cancer surgery; clinical outcome; cohort analysis; combination drug therapy; demographics; diagnostic procedure; disease free survival; drug approval; drug efficacy; drug safety; EGFR gene; epidemiology; first-line treatment; follow up; gene mutation; human; Korean EGFR registry; maintenance therapy; major clinical study; metastasis; molecularly targeted therapy; non small cell lung cancer; observational study; pathology; patient registry; personalized cancer therapy; progression free survival; prospective study; quality of life assessment; retrospective study; risk factor; second-line treatment; smoking; South Korea; South Korean; university hospital; young adult; aged; clinical trial; drug therapy; female; genetics; lung tumor; male; middle aged; mortality; multicenter study; mutation; non small cell lung cancer; quality of life; register; therapy English 2025 2025-01 10.1111/crj.70043 바로가기 바로가기 바로가기 바로가기
Article Treatment of Premature Ovarian Failure Mouse Model Using Granulosa-Like Cells Derived from Wharton’s Jelly-Mesenchymal Stem Cells Premature ovarian failure (POF) is a significant reproductive disorder characterized by the loss of ovarian function, leading to infertility and endocrine disruption. Hormone replacement therapy (HRT) remains the most commonly used clinical treatment for POF. However, in patients with a history of ovarian or breast cancer, HRT poses significant risks, necessitating the development of alternative approaches. Stem cell-based therapy has emerged as a promising option for treating female infertility disorders such as POF. This study aimed to evaluate the therapeutic effects of ovarian granulosa-like cells (OGLCs) derived from Wharton’s jelly-mesenchymal stem cells (WJ-MSCs) in a POF mouse model. WJ-MSCs were successfully differentiated into OGLCs using combination with a growth factor cocktails, as confirmed by the significant upregulation of granulosa cell-specific markers (P < 0.01). To assess their therapeutic potential, POF was induced in female mice using cyclophosphamide and busulfan, and OGLCs were injected into the ovaries. After 3 weeks, vaginal smear analysis revealed restoration of estrus cycle in OGLC-treated mice. Enzyme-linked immunosorbent assay analysis demonstrated the recovery of serum 17β-estradiol and follicle-stimulating hormone levels (P < 0.05), while histological staining confirmed increased follicular development and restoration of ovarian structure. Furthermore, real-time quantitative polymerase chain reaction analysis showed a significant upregulation of genes related to follicular development and primordial follicle activation, including downstream molecules of the mTOR/PI3K pathway, following OGLCs treatment. These findings suggest that OGLCs possess a strong potential for restoring ovarian function in POF. This study provides evidence supporting the use of OGLCs as a novel cell-based therapeutic approach for female reproductive diseases. Copyright 2025, Mary Ann Liebert, Inc., publishers. Lee, Sang-Yun; Bharti, Dinesh; Lee, Won-Jae; Son, Young-Bum; Jin, Yeung Bae; Lee, Hyeon-Jeong; Jo, Chan-Hee; Oh, Seong-Ju; Hong, Chae-Yeon; Kang, Seo-Yoon; Park, Sanghyeon; Choe, Yong-Ho; Lee, Sung-Lim College of Veterinary Medicine, Gyeongsang National University, Jinju, South Korea; Division of Pulmonary, Critical Care, Sleeping and Occupational Medicine, School of Medicine, Indiana University, Indianapolis, IN, United States; College of Veterinary Medicine, Kyungpook National University, Daegu, South Korea; Department of Obstetrics, College of Veterinary Medicine, Chonnam National University, Gwangju, South Korea; College of Veterinary Medicine, Gyeongsang National University, Jinju, South Korea; College of Veterinary Medicine, Gyeongsang National University, Jinju, South Korea; College of Veterinary Medicine, Gyeongsang National University, Jinju, South Korea; College of Veterinary Medicine, Gyeongsang National University, Jinju, South Korea; College of Veterinary Medicine, Gyeongsang National University, Jinju, South Korea; College of Veterinary Medicine, Gyeongsang National University, Jinju, South Korea; College of Veterinary Medicine, Gyeongsang National University, Jinju, South Korea; College of Veterinary Medicine, Gyeongsang National University, Jinju, South Korea, Research Institute of Life Sciences, Gyeongsang National University, Jinju, South Korea; College of Veterinary Medicine, Gyeongsang National University, Jinju, South Korea, Research Institute of Life Sciences, Gyeongsang National University, Jinju, South Korea 57216913305; 56946650400; 57205486455; 57197735518; 59681564200; 57202973938; 57221808828; 57220159013; 58411924300; 59681304900; 59772824800; 57202927556; 16678898100 yhchoe@gnu.ac.kr; sllee@gnu.ac.kr; Stem Cells and Development STEM CELLS DEV 1547-3287 1557-8534 34 9-10 SCIE CELL & TISSUE ENGINEERING;HEMATOLOGY;MEDICINE, RESEARCH & EXPERIMENTAL;TRANSPLANTATION 2024 2 46.8 N/A 0 differentiation; granulosa-like cells; premature ovarian failure; stem cell therapy; Wharton’s jelly-mesenchymal stem cells Animals; Cell Differentiation; Disease Models, Animal; Female; Granulosa Cells; Humans; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Primary Ovarian Insufficiency; Wharton Jelly; busulfan; cell surface marker; cyclophosphamide; estradiol; fat droplet; follitropin; growth factor; mammalian target of rapamycin; animal cell; animal experiment; animal model; animal tissue; Article; bone development; breast cancer; cell differentiation; controlled study; early menopause; enzyme immunoassay; enzyme linked immunosorbent assay; estradiol blood level; estrus cycle; female; female infertility; flow cytometry; gene expression; gene expression profiling; granulosa cell; histology; hormone substitution; human; human cell; immunofluorescence assay; mesenchymal stem cell; mouse; mTOR signaling; nonhuman; ovary cancer; ovary follicle development; ovary function; Pi3K/Akt signaling; premature ovarian failure; primordial follicle; reaction analysis; real time polymerase chain reaction; RNA extraction; stem cell transplantation; umbilical cord; upregulation; uterus tissue; Wharton jelly; animal; cell differentiation; cytology; disease model; mesenchymal stem cell transplantation; metabolism; pathology; premature ovarian failure; therapy; transplantation English Final 2025 10.1089/scd.2025.0027 바로가기 바로가기 바로가기
Article A Coordination Layer for Time Synchronization in Level-4 Multi-vECU Simulation In automotive software development, testing and validation workloads are often concentrated at the end of the development cycle, leading to delays and late-stage issue discovery. To address this, virtual Electronic Control Units (vECUs) have gained attention for enabling earlier-stage verification. In our previous work, we developed a Level-4 vECU using a hardware-level emulator. However, when simulating multiple vECUs with independent clocks across distributed emulators, we observed poor timing reproducibility due to the lack of explicit synchronization. To solve this, we implemented an integration layer compliant with the functional mock-up interface (FMI), a widely used standard for simulation tool interoperability. The layer enables synchronized simulation between a centralized simulation master and independently running vECUs. We also developed a virtual CAN bus model to simulate message arbitration and validate inter-vECU communication behavior. Simulation results show that our framework correctly reproduces CAN arbitration logic and significantly improves timing reproducibility compared to conventional Linux-based interfaces. To improve simulation performance, the FMI master algorithm was parallelized, resulting in up to 85.2% reduction in simulation time with eight vECUs. These contributions offer a practical solution for synchronizing distributed Level-4 vECUs and lay the groundwork for future cloud-native simulation of automotive systems. Kim, Hyeongrae; Lee, Harim; Cho, Jeonghun Kyungpook Natl Univ, Sch Elect & Elect Engn, Daegu 41566, South Korea 57203064517; 58875678400; 7403536198 hrsin95@knu.ac.kr; hw05165@knu.ac.kr; jcho@knu.ac.kr; ELECTRONICS ELECTRONICS-SWITZ 2079-9292 14 8 SCIE ENGINEERING, ELECTRICAL & ELECTRONIC;PHYSICS, APPLIED;COMPUTER SCIENCE, INFORMATION SYSTEMS 2024 2.6 46.9 0 2025-05-07 0 0 virtual electronic control unit (vECU); AUTOSAR; Renode; functional mock-up interface (FMI) AUTOSAR; functional mock-up interface (FMI); Renode; virtual electronic control unit (vECU) Electronic guidance systems; Mockups; Model checking; Testbeds; AutoSAR; Coordination layer; Electronics control unit; Functional mock-up interface; Functionals; Level 4; Mock up; Renode; Reproducibilities; Virtual electronic control unit; UNIX English 2025 2025-04-21 10.3390/electronics14081690 바로가기 바로가기 바로가기 바로가기
Article A Privacy-Preserving Authentication Scheme Using PUF and Biometrics for IoT-Enabled Smart Cities With the advancement of communication technology, smart cities can provide remote services to users using mobile devices and Internet of Things (IoT) sensors in real time. However, the collected data in smart cities include sensitive personal information and data transmitted over public wireless channels, leaving the network vulnerable to security attacks. Thus, robust and secure authentication is critical to verify legitimate users and prevent malicious attacks. This paper reviews a recent authentication scheme for smart cities and identifies its susceptibilities to attacks, including insider attacks, sensor node capture, user impersonation, and random number leakage. We propose a secure and privacy-preserving authentication scheme for smart cities to resolve these security weaknesses. The scheme enables mutual authentication by incorporating biometric features to verify identity and using the physical unclonable function to prevent physical attacks. We evaluate the security of the proposed scheme via informal and formal analyses, including Burrows-Abadi-Needham logic, the real-or-random model, and the Automated Validation of Internet Security Protocols and Applications simulation tool. Finally, we compare the performance, demonstrating that the proposed scheme has better efficiency and security than existing schemes. Consequently, the proposed scheme is suitable for resource-constrained IoT-enabled smart cities. Kim, Chaeeon; Son, Seunghwan; Park, Youngho Kyungpook Natl Univ, Sch Elect & Elect Engn, Daegu 41566, South Korea 59469213900; 57221744477; 56962990300 chaeon@knu.ac.kr; sonshawn@knu.ac.kr; parkyh@knu.ac.kr; ELECTRONICS ELECTRONICS-SWITZ 2079-9292 14 10 SCIE ENGINEERING, ELECTRICAL & ELECTRONIC;PHYSICS, APPLIED;COMPUTER SCIENCE, INFORMATION SYSTEMS 2024 2.6 46.9 0 2025-06-11 1 1 authentication; internet of things (IoT); smart city; fuzzy extractor; physically unclonable function; privacy preserving KEY EXCHANGE; CITY; SECURITY; PROTOCOL; INTERNET; CHALLENGES; DESIGN authentication; fuzzy extractor; internet of things (IoT); physically unclonable function; privacy preserving; smart city Authentication; Digital arithmetic; Privacy by design; Privacy-preserving techniques; Authentication scheme; Communicationtechnology; Fuzzy extractors; Internet of thing; Personal information; Physically unclonable functions; Privacy preserving; Privacy-preserving authentication; Real- time; Remote services; Sensitive data English 2025 2025-05-11 10.3390/electronics14101953 바로가기 바로가기 바로가기 바로가기
Article A Seamless Authentication Scheme for Edge-Assisted Internet of Vehicles Environments Using Chaotic Maps Internet of Vehicles (IoV) is a concept that combines IoT and vehicular ad hoc networks. In IoV environments, vehicles constantly move and communicate with other roadside units (edge servers). Due to the vehicles' insufficient computing power, repetitive authentication procedures can be burdensome for automobiles. In recent years, numerous authentication protocols for IoV environments have been proposed. However, there is no study that considers both re-authentication and handover authentication situations, which are essential for seamless communication in vehicular networks. In this study, we propose a chaotic map-based seamless authentication scheme for edge-assisted IoV environments. We propose authentication protocols for initial, handover, and re-authentication situations and analyze the security of our scheme using informal methods, the real-or-random (RoR) model, and the Scyther tool. We also compare the proposed scheme with existing schemes and show that our scheme has superior performance and provides more security features. To our knowledge, This paper is the first attempt to design an authentication scheme considering both handover and re-authentication in the IoV environment. Son, Seunghwan; Kwon, Deokkyu; Park, Youngho Kyungpook Natl Univ, Sch Elect & Elect Engn, Daegu 41566, South Korea 57221744477; 57221739597; 56962990300 sonshawn@knu.ac.kr; kdk145@knu.ac.kr; parkyh@knu.ac.kr; ELECTRONICS ELECTRONICS-SWITZ 2079-9292 14 4 SCIE ENGINEERING, ELECTRICAL & ELECTRONIC;PHYSICS, APPLIED;COMPUTER SCIENCE, INFORMATION SYSTEMS 2024 2.6 46.9 0 2025-05-07 0 0 chaotic map; internet of vehicles; mutual authentication; seamless authentication; Scyther tool chaotic map; internet of vehicles; mutual authentication; Scyther tool; seamless authentication English 2025 2025-02 10.3390/electronics14040672 바로가기 바로가기 바로가기 바로가기
Article Design Strategies for BCAT Structures: Enhancing DRAM Reliability and Mitigating Row Hammer Effect This study investigates the impact of four parameters-gate angles, fin height controlled through gate overlaps and the distance from fin to source/drain, and substrate bottom doping concentration-on the row hammer effect (RHE) in DRAM cells. The influence of adjacent and passing gates on the DRAM cell body potential was identified as a key factor in D0 and D1 failures. The tolerance for D1 and D0 failures was analyzed, defined as the threshold number of pulses required to induce a 0.6 V change in the storage node voltage (from 1.2 V to 0.6 V for a D1 failure or from 0 V to 0.6 V for a D0 failure). D1 (D0) failure tolerances with the slope from the top of the top gate (theta angle) of 3 degrees, the height of the TiN gate covering the fin (Hfinₒᵥₑᵣₗₐₚ) of 12.5 nm, and the height of the fin (Hfin) of 12.5 nm are 1.26 x 106 (4.8 x 106), 1.14 x 106 (4 x 107), and 7.5 x 105 (4.8 x 105), respectively. Higher theta angles and smaller fin heights generally result in higher RHE tolerances. Although decreasing the fin height reduced the RHE, it also decreased the on-current and resulted in an increase in the threshold voltage (VT) and the subthreshold swing (SS). In addition, by increasing the substrate bottom doping concentration (Pdopbₒₜ), we improve RHE tolerance twice its original level without reducing the on-current. Therefore, designing a buried channel array transistor (BCAT) structure requires careful consideration of these trade-offs, and a thorough understanding of the underlying mechanism is crucial to devising strategies that reduce RHE tolerance. The findings of this study are expected to contribute significantly to the development of next-generation DRAM architectures, enhancing stability and performance. By addressing the reliability challenges posed by advanced scaling, this study paves the way for the ongoing advancement of DRAM technology for high-density and high-performance applications. Im, Jisung; Kim, Hansol; Kim, Hyungjin; Woo, Sung Yun Kyungpook Natl Univ, Sch Elect & Elect Engn, Daegu 41566, South Korea; Hanyang Univ, Div Mat Sci & Engn, Seoul 04763, South Korea 59325078500; 58542537300; 57218447834; 57212495752 hkim12@hanyang.ac.kr; sywoo@knu.ac.kr; ELECTRONICS ELECTRONICS-SWITZ 2079-9292 14 3 SCIE ENGINEERING, ELECTRICAL & ELECTRONIC;PHYSICS, APPLIED;COMPUTER SCIENCE, INFORMATION SYSTEMS 2024 2.6 46.9 0 2025-05-07 0 0 DRAM; buried channel array transistor (BCAT); TCAD simulation; row hammer effect (RHE); D0 failure; D1 failure ROWHAMMER buried channel array transistor (BCAT); D0 failure; D1 failure; DRAM; row hammer effect (RHE); TCAD simulation English 2025 2025-02 10.3390/electronics14030499 바로가기 바로가기 바로가기 바로가기
Article REO: Revisiting Erase Operation for Improving Lifetime and Performance of Modern NAND Flash-Based SSDs This work investigates a new erase scheme in NAND flash memory to improve the lifetime and performance of modern solid-state drives (SSDs). In NAND flash memory, an erase operation applies a high voltage (e.g., >20 V) to flash cells for a long time (e.g., >3.5 ms), which degrades cell endurance and potentially delays user I/O requests. While a large body of prior work has proposed various techniques to mitigate the negative impact of erase operations, no work has yet investigated how erase latency and voltage should be set to fully exploit the potential of NAND flash memory; most existing techniques use a fixed latency and voltage for every erase operation, which is set to cover the worst-case operating conditions. To address this, we propose Revisiting Erase Operation, (REO) a new erase scheme that dynamically adjusts erase latency and voltage depending on the cells' current erase characteristics. We design REO by two key apporaches. First, REO accurately predicts such near-optimal erase latency based on the number of fail bits during an erase operation. To maximize its benefits, REO aggressively yet safely reduces erase latency by leveraging a large reliability margin present in modern SSDs. Second, REO applies near-optimal erase voltage to each WL based on its unique erase characteristics. We demonstrate the feasibility and reliability of REO using 160 real 3D NAND flash chips, showing that it enhances SSD lifetime over the conventional erase scheme by 43% without change to existing NAND flash chips. Our system-level evaluation using eleven real-world workloads shows that an REO-enabled SSD reduces average I/O performance and read tail latency by 12% and 38%, respectivley, on average over a state-of-the-art technique. Kim, Beomjun; Kim, Myungsuk Kyungpook Natl Univ, Sch Comp Sci & Engn, Daegu 37224, South Korea 57743131700; 57194859467 beomjun0816@knu.ac.kr; ms.kim@knu.ac.kr; ELECTRONICS ELECTRONICS-SWITZ 2079-9292 14 4 SCIE ENGINEERING, ELECTRICAL & ELECTRONIC;PHYSICS, APPLIED;COMPUTER SCIENCE, INFORMATION SYSTEMS 2024 2.6 46.9 0 2025-05-07 0 0 solid-state drives (SSDs); NAND flash memory; erase operation; SSD lifetime; I/O performance MITIGATION erase operation; I/O performance; NAND flash memory; solid-state drives (SSDs); SSD lifetime English 2025 2025-02 10.3390/electronics14040738 바로가기 바로가기 바로가기 바로가기
Article Test for conditional Poissonity in integer-valued conditional autoregressive models The Poisson distribution is a representative distribution for discrete data, much like the normal distribution is for continuous data. Many time series models for count data have been developed based on the Poisson distribution. However, studies examining the validity of the Poisson assumption in these time series models have been relatively scarce. This study addresses the problem of testing for conditional Poissonity in integer-valued conditional autoregressive models. For this purpose, we introduce a test statistic based on the information matrix of the likelihood function. Under regularity conditions, it is shown that the proposed test has an asymptotic null distribution following a chi-square distribution. Simulation results demonstrate the validity of the proposed test. Additionally, a real data analysis is provided for illustration. Kang, Jiwon; Song, Junmo Jeju Natl Univ, Dept Data Sci, Jeju, South Korea; Kyungpook Natl Univ, Dept Stat, Daegu, South Korea 56123620200; 23470710200 jsong@knu.ac.kr; JOURNAL OF STATISTICAL COMPUTATION AND SIMULATION J STAT COMPUT SIM 0094-9655 1563-5163 95 2 SCIE COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS;STATISTICS & PROBABILITY 2024 1.2 47.0 0 2025-05-07 0 0 Integer-valued conditional autoregressive models; Poisson autoregressive models; test for Poissonity; information matrix test PARAMETER CHANGE; TIME-SERIES information matrix test; Integer-valued conditional autoregressive models; Poisson autoregressive models; test for Poissonity English 2025 2025-01-22 10.1080/00949655.2024.2431097 바로가기 바로가기 바로가기 바로가기
Article Flocking dynamics of agents moving with a constant speed and a randomly switching topology In this paper, we present a sufficient framework to exhibit the sample path-wise asymptotic flocking dynamics of the Cucker-Smale model with unit-speed constraint and the randomly switching network topology. We employ a matrix formulation of the given equation, which allows us to evaluate the diameter of velocities with respect to the adjacency matrix of the network. Unlike the previous result on the randomly switching Cucker-Smale model, the unit-speed constraint disallows the system to be considered as a nonautonomous linear ordinary differential equation on velocity vector, which forces us to get a weaker form of the flocking estimate than the result for the original Cucker-Smale model. Ahn, Hyunjin; Shim, Woojoo Myongji Univ, Dept Math, Seoul, Gyeonggi Do, South Korea; Kyungpook Natl Univ, Dept Math Educ, Daegu, South Korea ; Shim, Woojoo/GYJ-0778-2022 57222812591; 57204943631 wjshim@knu.ac.kr; EUROPEAN JOURNAL OF APPLIED MATHEMATICS EUR J APPL MATH 0956-7925 1469-4425 36 2 SCIE MATHEMATICS, APPLIED 2024 1.1 47.1 0 2025-05-07 0 0 asymptotic flocking; Cucker-Smale; directed graph; multi-agent system; randomly switching topology; unit-speed constraint CUCKER-SMALE FLOCKING; BI-CLUSTER FLOCKING; ROOTED LEADERSHIP; MODEL; EMERGENCE; SYNCHRONIZATION; CONSENSUS; NETWORKS; BEHAVIOR; SYSTEM asymptotic flocking; Cucker-Smale; directed graph; multi-agent system; randomly switching topology; unit-speed constraint Multi agent systems; Ordinary differential equations; Asymptotic flocking; Asymptotics; Constant speed; Cucke-smale; Network topology; Randomly switching topologies; Sample path; Smale model; Speed constraints; Unit-speed constraint; Directed graphs English 2025 2025-04 10.1017/s0956792524000214 바로가기 바로가기 바로가기 바로가기
Article Minimal codewords over finite fields derived from certain graphs Throughout this paper, we explore the number of non-equivalent minimal codewords of linear codes derived from certain graphs. We propose a lower bound on the number of non-equivalent minimal codewords over Fq associated with graphs of diameter 2. Beyond diameter 2, we also determine the number of non-equivalent minimal codewords over Fq for graphs with arbitrary diameter. To achieve this, we study n-cycles and the row spaces generated by some rows from the generator matrix of linear codes. Primarily, our focus is on the number of non-equivalent minimal codewords, and we also provide precise construction methods for identifying minimal codewords in linear codes. To support our results, we present some examples in this work. © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2025. Kim, Boran Department of Mathematics Education, Kyungpook National University, Daegu, 41566, South Korea 56909090000 bkim21@knu.ac.kr; Cryptography and Communications CRYPTOGR COMMUN 1936-2447 1936-2455 SCIE COMPUTER SCIENCE, THEORY & METHODS;MATHEMATICS, APPLIED 2024 1.1 47.1 0 2025-05-07 0 Graphs; Linear codes; Minimal codewords Code-words; Construction method; Finite fields; Generator matrix; Graph; Linear codes; Low bound; Minimal codeword; N cycles; Turbo codes English Article in press 2025 10.1007/s12095-025-00793-8 바로가기 바로가기 바로가기
Article Can the subject reliably reproduce maximum voluntary contraction of temporalis and masseter muscles in surface EMG? Objective: To evaluate the repeatability of the surface EMG variables of myoelectric signals from the masseter and temporalis muscles according to three methods to induce maximum voluntary contraction (MVC) in healthy adults. Methods: Thirty healthy young subjects performed the following three MVC tasks three times each in three sessions on the same day without replacing surface electrodes: clenching the teeth (MVCIC) and biting down on two cotton rolls bilaterally with the posterior teeth (MVCBP) or first molars (MVCB6). Results: The intra-class correlation coefficient (ICC) of the amplitudes during the three MVC tasks ranged from 65 to 79%. The ICCs of the spectral variables ranged from 78 to 86%. The ICCs of the asymmetry index of the masseter ranged from 77 to 86%, and those of the activity index ranged from 68 to 90%. Conclusion: The surface EMG measurements according to the three MVC methods exhibited good to excellent reproducibility. © 2022 Taylor & Francis Group, LLC. Jung, Jae-Kwang; Im, Yeong-Gwan Department of Oral Medicine, School of Dentistry, IHBR, Kyungpook National University, Daegu, South Korea; Department of Oral Medicine, Dental Science Research Institute, School of Dentistry, Chonnam National University, Gwangju, South Korea 55970994400; 56197647300 imygwise@jnu.ac.kr; Cranio - Journal of Craniomandibular and Sleep Practice CRANIO 0886-9634 2151-0903 43 3 SCIE DENTISTRY, ORAL SURGERY & MEDICINE 2024 1.9 47.2 0 2025-05-07 5 Electromyography; masseter; reproducibility; temporalis Adult; Electromyography; Female; Humans; Male; Masseter Muscle; Muscle Contraction; Reproducibility of Results; Temporal Muscle; Young Adult; adult; electromyography; female; human; male; masseter muscle; muscle contraction; physiology; procedures; reproducibility; temporalis muscle; young adult English Final 2025 10.1080/08869634.2022.2142234 바로가기 바로가기 바로가기
Article A radar-based investigation of precipitation growth and decay in South Korea Understanding precipitation growth and decay (GD) is necessary to improve the predictability of precipitation. Investigating the precipitation GD has been mostly based on an Eulerian approach, which examines the physical characteristics in a fixed coordinate system. In contrast, a Lagrangian approach provides a way to monitor the temporal evolution following the motion of the precipitation system. In this study, we employ a semi-Lagrangian advection framework to quantitatively retrieve radar-based GD of precipitation in South Korea. Additionally, we explore the dependence of GD on the following factors: flow direction, flow speed, and relative geographical location to the topography and land–ocean boundary. Our findings reveal that the flow direction significantly influences the spatial distribution of GD. The growth generally tends to occur on the windward side of the mountain range and vice versa on the lee side. The flow speed affects the intensity of GD. Furthermore, we examine the diurnal variability of GD. Due to strong orographic forcing on the diurnal variation, the unique geographical features of South Korea created diurnal patterns near Seoul by land–ocean breeze circulation and on the windward side of the mountain ranges (inland) by solar heating. The GD in South Korea exhibits two diurnal peaks of growth: an early morning peak over the ocean and an afternoon peak on the land. A monthly variation is also observed, with the most intense growth taking place in August. The findings of this study will aid in improving nowcasting algorithms that account for growth and decay, while also supporting forecasters in their predictive efforts. © 2025 The Author(s). Quarterly Journal of the Royal Meteorological Society published by John Wiley & Sons Ltd on behalf of Royal Meteorological Society. Kim, Kwonil; Tsai, Chia-Lun; Lee, GyuWon BK21 Weather Extremes Education & Research Team, Department of Atmospheric Sciences, Center for Atmospheric REmote Sensing (CARE), Kyungpook National University, Daegu, South Korea, School of Marine and Atmospheric Sciences, Stony Brook University, Stony Brook, NY, United States; Department of Atmospheric Sciences, Chinese Culture University, Taipei, Taiwan; BK21 Weather Extremes Education & Research Team, Department of Atmospheric Sciences, Center for Atmospheric REmote Sensing (CARE), Kyungpook National University, Daegu, South Korea 57191964318; 55474132500; 7404852271 gyuwon@knu.ac.kr; Quarterly Journal of the Royal Meteorological Society Q J ROY METEOR SOC 0035-9009 1477-870X SCIE METEOROLOGY & ATMOSPHERIC SCIENCES 2024 2.9 47.3 0 2025-05-07 0 diurnal variation; Lagrangian precipitation development; mesoscale flow; orographic effect English Article in press 2025 10.1002/qj.4988 바로가기 바로가기 바로가기
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