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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Article | Lower albumin level and longer disease duration are risk factors of acute kidney injury in hospitalized children with nephrotic syndrome | Background: Children with nephrotic syndrome (NS) are at an increased risk of acute kidney injury (AKI) and the incidence of AKI in this population is reportedly increasing. This study aimed to investigate the incidence, clinical profiles, and risk factors of AKI in hospitalized children with NS through a nationwide study. Methods: This retrospective multicenter study included 14 pediatric nephrology centers in Korea. From 2013 to 2017, a total of 814 patients with idiopathic NS were cared for at participating centers. Among them, 363 patients were hospitalized for NS and investigated in this study. Results: A total of 363 children with NS were hospitalized 574 times. AKI occurred in 93 admissions (16.2%) of 89 patients: 30 (32.3%) stage 1; 24 (25.8%) stage 2; and 39 (41.9%) stage 3. Multivariate logistic regression analysis showed that longer disease duration, lower albumin level, and methylprednisolone pulse treatment were significantly associated with AKI development in hospitalized children with NS. AKI was associated with a longer hospital stay than non-AKI (median 10 vs. 7 days, P= 0.001). Among 93 admissions, 85 (91.4%) episodes recovered from AKI without complication, whereas 6 (6.5%) progressed to advanced chronic kidney disease (CKD). Conclusions: AKI is not uncommon in hospitalized children with NS, and its incidence in this nationwide study was 16.2%. Risk factors for AKI in hospitalized children with NS include longer disease duration, lower albumin level, and methylprednisolone pulse therapy. Pediatric NS patients with these characteristics should be under more strict scrutiny for the occurrence of AKI. | Yang, Eun Mi; Yoo, Kee Hwan; Ahn, Yo Han; Kim, Seong Heon; Lee, Jung Won; Chung, Woo Yeong; Cho, Min Hyun; Kim, Kee Hyuck; Cho, Heeyeon; Lee, Mee Jeong; Suh, Jin-Soon; Hyun, Hye Sun; Lee, Jiwon M.; Cho, Myung Hyun; Kim, Ji Hyun; Ha, Il-Soo; Cheong, Hae Il; Kang, Hee Gyung | Chonnam Natl Univ Hosp, Dept Pediat, Gwangju, South Korea; Korea Univ, Guro Hosp, Seoul, South Korea; Seoul Natl Univ, Childrens Hosp, 101 Daehak Ro, Seoul 03080, South Korea; Seoul Natl Univ, Coll Med, 101 Daehak Ro, Seoul 03080, South Korea; Pusan Natl Univ, Childrens Hosp, Yangsan, South Korea; Ewha Womans Univ, Coll Med, Seoul, South Korea; Inje Univ, Busan Paik Hosp, Busan, South Korea; Kyungpook Natl Univ, Sch Med, Daegu, South Korea; NHIC Ilsan Hosp, Goyang, South Korea; Sungkyunkwan Univ, Samsung Med Ctr, Seoul, South Korea; Dankook Univ, Coll Med, Cheonan, South Korea; Catholic Univ Korea, Coll Med, Bucheon St Marys Hosp, Seoul, South Korea; Catholic Univ, Coll Med, St Vincents Hosp, Suwon, South Korea; Chungnam Natl Univ Hosp, Daejeon, South Korea; Hallym Univ, Sacred Heart Hosp, Anyang, South Korea; Seoul Natl Univ, Bundang Hosp, Seongnam, South Korea; Seoul Natl Univ, Med Res Ctr, Kidney Res Inst, Coll Med, Seoul, South Korea; Seoul Natl Univ, Wide River Inst Immunol, Hongcheon, South Korea | Kim, Seong/AAD-8853-2020; Lee, Yong Jae/GLR-4153-2022; Suh, Jin-Soon/GNH-6543-2022; cho, myung hyun/AEB-7941-2022 | 56665095200; 7202592702; 57219957477; 57213778393; 26028875500; 8605959600; 7401727726; 7409325956; 15724272900; 56080197500; 35222513700; 57204538255; 57209882209; 57203276948; 58607599100; 7005904938; 34567974000; 7404071546 | kanghg@snu.ac.kr; | PEDIATRIC NEPHROLOGY | PEDIATR NEPHROL | 0931-041X | 1432-198X | 36 | 3 | SCIE | PEDIATRICS;UROLOGY & NEPHROLOGY | 2021 | 3.652 | 27.3 | 0.91 | 2025-07-30 | 6 | 7 | Nephrotic syndrome; Acute kidney injury; Children; Hospitalization; Risk factors | METHYLPREDNISOLONE PULSE THERAPY; RENAL-FAILURE; CHILDHOOD; KDIGO; AKIN; MANAGEMENT; CRITERIA; RIFLE | Acute kidney injury; Children; Hospitalization; Nephrotic syndrome; Risk factors | Acute Kidney Injury; Albumins; Child; Child, Hospitalized; Humans; Incidence; Methylprednisolone; Nephrotic Syndrome; Retrospective Studies; Risk Factors; albumin; methylprednisolone; albuminoid; methylprednisolone; acute kidney failure; adolescent; albumin blood level; Article; child; chronic kidney failure; clinical feature; clinical outcome; controlled study; disease assessment; disease association; disease duration; disease exacerbation; drug pulse therapy; female; hospital admission; hospitalization; human; incidence; Korea; major clinical study; male; multicenter study; nephrotic syndrome; priority journal; retrospective study; risk factor; acute kidney failure; clinical trial; complication; hospitalized child; nephrotic syndrome | English | 2021 | 2021-03 | 10.1007/s00467-020-04740-y | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | Article | Piezoelectric polymer energy harvesting system fluctuating in a high speed wind-flow around a running electric vehicle | The battery of electric vehicles (EVs) is the only power source for the operation of an electric motor, heating and cooling devices, and many other auxiliaries. Therefore, the EV may be vulnerable to electricity shortage during running. It may be good if turbulent flow or vortex induced vibrations occurring around a vehicle body can be transformed into electricity by a piezoelectric energy harvester. In this study, an electric energy harvester has been developed in the forms of thin piezoelectric polymer beams and plates in order to supply auxiliary electric power for EV. The piezoelectric thin beam and plate can be installed as a grill structure or on the surface of a car while two edges of the harvesting structures are fixed and they fluctuate due to the various high-speed airflow-induced vibrations during running of the vehicle. The vortex shedding pressures around the piezoelectric systems and a whole car are computed on the basis of computational fluid dynamic transient analyses with FLUENT. The displacements and resulting voltages of energy harvesting structures are computed by using ANSYS piezoelectric finite element analyses which use the input loadings of the transient vortex shedding pressures obtained from CFD. As results of analyses, a reasonable amount of electric power applicable for the charge of an EV battery can be harvested from the passing wind around a vehicle. The 0.12 mm-thin PVDF beam-type (260 mm x 10 mm) and the plate-type (75 mm x 30 mm) generated the maximum 61.43 volt and 21.5 mW power and 4.77 volt and 0.191 mW at the air-speed of 90 km h(-1) in the wind tunnel tests, respectively. The two types of harvesting systems installed on a car were also tested while driving the real car. The test results showed the good agreements with numerical predictions and wind tunnel test results. | Kim, Cheol; Park, Chang-min; Yoon, Jin-young; Park, Sang-young | Kyungpook Natl Univ, Dept Mech Engn, 80 Daehak Ro, Daegu 702701, South Korea; Hyundai Motor Co, R&D Div, 150 Hyundaiyeonguso Ro, Hwaseong Si 18280, Gyeonggi Do, South Korea; Hyundai NGV, 314 Dong,1 Gwanak Ro, Seoul 08826, South Korea | Park, Chang/J-8409-2016; Yoon, Jin-Young/JAX-4858-2023; Park, Sang-Young/F-5989-2013 | kimchul@knu.ac.kr; | SMART MATERIALS AND STRUCTURES | SMART MATER STRUCT | 0964-1726 | 1361-665X | 30 | 1 | SCIE | INSTRUMENTS & INSTRUMENTATION;MATERIALS SCIENCE, MULTIDISCIPLINARY | 2021 | 4.131 | 27.3 | 12 | energy harvesting; piezoelectric polymer; high speed flow; flutter; real car test | PERFORMANCE | English | 2021 | 2021-01 | 10.1088/1361-665x/abb98a | 바로가기 | 바로가기 | 바로가기 | |||||||||
| ○ | ○ | Article | Development of Korean Indigenous Low-Temperature-Tolerant Yeast for Enhancing the Flavor of Yakju | Yakju, a traditional fermented beverage in Korea, is prepared using various raw materials and methods, and, hence, exhibits various characteristics. Low-temperature-fermented yakju can inhibit the growth of undesirable bacteria and is known for its unique flavor and refreshing taste. To increase the production of volatile aromatic compounds in yakju, strains with strong resistance to low temperatures and excellent production of volatile aromatic compounds were screened from indigenous fruits (grape, persimmon, plum, aronia, wild grape) and nuruk in Korea. One Saccharomyces cerevisiae and three non-Saccharomyces strains were finally screened, and yakju was fermented at 15 degrees C through mono/co-culture. The analysis of volatile aromatic compounds showed that S. cerevisiae W153 produced 1.5 times more isoamyl alcohol than the control strain and reduced the production of 2,3-butanediol by a third. Similarly, a single culture of Pichia kudriavzevii N373 also produced 237.7 mg/L of ethyl acetate, whereas Hanseniaspora vineae G818 produced ~11 times greater levels of 2-phenethyl acetate than the control. Alternatively, Wickerhamomyces anomalus A159 produced 95.88 mg/L of ethyl hexadecanoate. During principal component analysis, we also observed that the co-culture sample exhibited characteristics of both volatile aroma compounds of the single cultured sample of each strain. Our results suggest that yakju with unique properties can be prepared using various non-Saccharomyces strains. | Park, Jong-Beom; Choi, Jun-Su; Park, Hye-Won; Lee, Sae-Byuk; Park, Heui-Dong | Kyungpook Natl Univ, Sch Food Sci & Biotechnol, 80 Daehakro, Daegu 41566, South Korea; Kyungpook Natl Univ, Inst Fermentat Biotechnol, 80 Daehakro, Daegu 41566, South Korea | ; Choi, Jun-Su/MVY-2121-2025 | 57223133187; 57195937178; 57339551900; 57188742752; 7601568590 | whdqja5743@naver.com;gigs6@naver.com;seraphicwon@naver.com;lsbyuck@nate.com;hpark@knu.ac.kr; | FERMENTATION-BASEL | FERMENTATION-BASEL | 2311-5637 | 7 | 4 | SCIE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | 2021 | 5.123 | 27.4 | 0.44 | 2025-07-30 | 4 | 5 | yakju; low-temperature fermentation; non-Saccharomyces; co-culture; volatile aromatic compound | NON-SACCHAROMYCES YEASTS; FERMENTATION TEMPERATURE; TORULASPORA-DELBRUECKII; WINE; AROMA; CEREVISIAE; ALCOHOL; 2,3-BUTANEDIOL; RELEASE; ACETOIN | Co-culture; Low-temperature fermentation; Non-Saccharomyces; Volatile aromatic compound; Yakju | English | 2021 | 2021-12 | 10.3390/fermentation7040260 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Utilizing Coffee Pulp and Mucilage for Producing Alcohol-Based Beverage | Coffee pulp, mucilage, and beans with mucilage were used to develop alcoholic beverages. The pulp of 45.3% pulp, 54.7% mucilage with seed, and 9.4% mucilage only were obtained during the wet processing of coffee. Musts were prepared for all to TSS (Total soluble solid) 18 degrees Bx and fermentation was carried out for 12-16 days until TSS decreased to 5 degrees Bx at 30 degrees C. Phenolic characteristics, chromatic structures, chemical parameters, and sensory characteristics were analyzed for the prepared alcoholic beverages. Methanol content, ester content, aldehyde, alcohol, total acidity, caffeine, polyphenols, flavonoids, chromatic structure, and hue of the alcoholic beverage from the pulp was 335 mg/L, 70.58 ppm, 9.15 ppm, 8.86 ABV%, 0.41%, 30.94 ppm, 845.7 mg GAE/g dry extract, 440.7 mg QE/g dry extract, 0.41, and 1.71, respectively. An alcoholic beverage from the pulp was found superior to an alcoholic beverage from mucilage with beans and a beverage from mucilage in sensory analysis. There is the possibility of developing fermented alcoholic beverages from coffee pulp and mucilage. However, further research is necessary for quality of the beans that were obtained from the fermentation with the mucilage. | Yadav, K. C.; Subba, Raju; Shiwakoti, Lila Devi; Dhungana, Pramesh Kumar; Bajagain, Rishikesh; Chaudhary, Dhiraj Kumar; Pant, Bhoj Raj; Bajgai, Tirtha Raj; Lamichhane, Janardan; Timilsina, Sampada; Upadhyaya, Jitendra; Dahal, Ram Hari | Tribhuvan Univ, Cent Campus Technol, Dharan 56700, Nepal; Natl Tea & Coffee Dev Board, Hile 56806, Dhankuta, Nepal; Univ Queensland, Sch Agr & Food Sci, Brisbane, Qld 4072, Australia; Kunsan Natl Univ, Dept Environm Engn, Kunsan 54150, South Korea; Korea Univ, Dept Environm Engn, Sejong Campus,2511 Sejong Ro, Sejong City 30019, South Korea; Nepal Acad Sci & Technol, Khumaltar 44700, Lalitpur, Nepal; Minhas Microbrewery Distillery & Winery, 1314 44 Ave NE, Calgary, AB T2E 6L6, Canada; Kathmandu Univ, Dept Biotechnol, Dhulikhel 45200, Nepal; McGill Univ, Dept Bioresource Engn, Macdonald Campus,Lakeshore Rd, Ste Anne De Bellevue, PQ 21111, Canada; Kyungpook Natl Univ, Sch Med, Dept Microbiol, Daegu 41944, South Korea | K C, Yadav/AAV-2675-2020; Dahal, Ram Hari/H-8673-2016; Chaudhary, Dhiraj Kumar/S-7772-2016; Chaudhary, Dhiraj/S-7772-2016; Bajagain, Rishikesh/ABB-2253-2020 | 57217390738; 57224070461; 57217380088; 56272137700; 57201025243; 57191257432; 35933590800; 6505844656; 13003212000; 57224090802; 56723750400; 57110097800 | ykcdng504@gmail.com;ft.subba@gmail.com;leela504s@gmail.com;prameshdhungana@gmail.com;rbajagain@gmail.com;dhirajchaudhary2042@gmail.com;environmentnast@gmail.com;tirraj@yahoo.com;ljanardan@ku.edu.np;sampadatimilsina118@gmail.com;jitu.upadhyaya@gmail.com;ramhari.dahal@gmail.com; | FERMENTATION-BASEL | FERMENTATION-BASEL | 2311-5637 | 7 | 2 | SCIE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | 2021 | 5.123 | 27.4 | 1.4 | 2025-07-30 | 17 | 20 | coffee pulp and mucilage; mucilage with beans; alcoholic beverage; sensory analysis | BIOETHANOL PRODUCTION; BY-PRODUCTS; FERMENTATION; CAFFEINE; ETHANOL; OPTIMIZATION; METHANOL; QUALITY; ACIDS; PH | Alcoholic beverage; Coffee pulp and mucilage; Mucilage with beans; Sensory analysis | English | 2021 | 2021-06 | 10.3390/fermentation7020053 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | A new classification on parallel Ricci tensor for real hypersurfaces in the complex quadric | First we introduce the notion of parallel Ricci tensor del Ric = 0 for real hypersurfaces in the complex quadric Q(m) = SOm+2/SOmSO2 and show that the unit normal vector field N is singular. Next we give a new classification of real hypersurfaces in the complex quadric Q(m) = SOm+2/SOmSO2 with parallel Ricci tensor. | Lee, Hyunjin; Suh, Young Jin | Kyungpook Natl Univ, Res Inst Real & Complex Manifolds RIRCM, Daegu 41566, South Korea; Kyungpook Natl Univ, Coll Nat Sci, Dept Math, Daegu 41566, South Korea; Kyungpook Natl Univ, Coll Nat Sci, Res Inst Real & Complex Manifolds, Daegu 41566, South Korea | 55706812200; 7202260479 | lhjibis@hanmail.net;yjsuh@knu.ac.kr; | PROCEEDINGS OF THE ROYAL SOCIETY OF EDINBURGH SECTION A-MATHEMATICS | P ROY SOC EDINB A | 0308-2105 | 1473-7124 | 151 | 6 | SCIE | MATHEMATICS, APPLIED;MATHEMATICS | 2021 | 1.327 | 27.5 | 2.24 | 2025-07-30 | 10 | 11 | Parallel Ricci tensor; A-isotropic; A-principal; Kahler structure; complex conjugation; complex quadric | ISOMETRIC REEB FLOW | complex conjugation; complex quadric; isotropic; Kahler structure; Parallel Ricci tensor; principal | English | 2021 | 2021-12 | 10.1017/prm.2020.83 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Molecular characterization and RNA interference responses of the lethal giant larvae gene in Diabrotica virgifera virgifera adults | High specificity for silencing target genes and single-copy target genes that yield clear phenotypes are two important factors for the success of RNA interference (RNAi). The lethal giant larvae (Lgl) gene appears to be an ideal gene for RNAi because RNAi can effectively suppress its expression and results in molting defects and mortality in Tribolium castaneum. To investigate the suitability of this gene for RNAi in other insects, we identified and characterized DvLgl from the western corn rootworm, Diabrotica virgifera virgifera, a species exhibiting high RNAi efficiency. DvLgl was expressed in all developmental stages and tissues investigated. The deduced DvLgl protein showed high amino-acid sequence identities and similar domain architecture to Lgls from other insect species. Despite many similarities among insect Lgls, RNAi-mediated suppression of DvLgl failed to produce a phenotype in D. v. virgifera adults. The difference in developing phenotypes could be attributed greatly to the level of gene suppression and the insect developmental stages for RNAi. These results highlight the variability in RNAi response among insects and showcase the importance of screening multiple target genes when conducting RNAi studies. Our findings are expected to help the design of future RNAi studies and future investigations of Lgl in insects. | Cooper, Anastasia M. W.; Song, Huifang; Shi, Xuekai; Yu, Zhitao; Kim, Young Ho; Silver, Kristopher; Zhang, Jianzhen; Zhu, Kun Yan | Kansas State Univ, Dept Entomol, 123 Waters Hall, Manhattan, KS 66506 USA; Shanxi Univ, Inst Appl Biol, Taiyuan, Shanxi, Peoples R China; Kyungpook Natl Univ, Dept Appl Biol, Sangju, Gyeongbuk, South Korea | ; liu, xiang/JED-7878-2023 | 56479855400; 57189370019; 57194102347; 59848241200; 58516491300; 8585652200; 23029273800; 7201425614 | anacooper@ksu.edu;kzhu@ksu.edu; | ARCHIVES OF INSECT BIOCHEMISTRY AND PHYSIOLOGY | ARCH INSECT BIOCHEM | 0739-4462 | 1520-6327 | 107 | 2 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY;ENTOMOLOGY;PHYSIOLOGY | 2021 | 2.454 | 27.5 | 0.3 | 2025-07-30 | 2 | 3 | European corn borer; lethal giant larvae; RNA interference; target gene selection; western corn rootworm | European corn borer; lethal giant larvae; RNA interference; target gene selection; western corn rootworm | Animals; Coleoptera; Genes, Insect; Genes, Lethal; RNA Interference; animal; beetle; gene; genetics; lethal gene; RNA interference | English | 2021 | 2021-06 | 10.1002/arch.21787 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Analysis of Factors Affecting Emergency Physicians' Attitudes toward Deceased Organ & Tissue Donation | Background: This study aimed to investigate differences in knowledge, and attitudes toward deceased organ and tissue donation of emergency physicians. Additionally, we analyzed factors affecting the attitudes toward deceased organ and tissue donation. Methods: We conducted a survey of specialists and residents registered with the Korean Society of Emergency Medicine in December 2020. The respondents' sex, age, position, personal registration for organ donation, experience of soliciting organ donation, participation in related education, knowledge, and attitude about brain death organ donation, and attitude toward stopping life-sustaining treatments were investigated. According to the characteristics of the respondents (specialists or residents, experience and education on organ and tissue donation), their knowledge and attitude toward deceased organ donation were compared. Stepwise hierarchical multiple regression analysis was used to investigate the factors affecting the attitudes toward deceased organ and tissue donation. Results: Of the total 428 respondents, there were 292 emergency medicine specialists and 136 medical residents. Specialists and those who registered or wished to donate organs had higher knowledge and attitude scores regarding deceased organ and tissue donation. Those who had experience recommending organ and tissue donation more than 6 times had higher knowledge scores on deceased organ and tissue donation and higher overall scores in attitude. Those who received education from the Korean Organ Donation Agency had higher knowledge scores. Specialists, and those who wished to donate or had registered as organ donors and had a higher life-sustaining treatment attitude score and knowledge about deceased organ and tissue donation, had more positive attitudes toward deceased organ and tissue donation. Conclusion: For more potential deceased organ and tissue donors to be referred for donation, there should be continuous education for emergency physicians on brain-dead organ and tissue donation-related knowledge and procedures. In addition, institutional or systematic improvements that can lead to organ donation when deciding on the withdrawal of life-sustaining treatment should be considered. | Lee, Dong Eun; Kim, Hyun; Park, Kwi Hwa; Park, Song Yi; Park, Seung Min; Jung, Yong Hun; Jeong, Wonjoon; Park, Kyung Hye | Kyungpook Natl Univ, Dept Emergency Med, Chilgok Hosp, Sch Med, Daegu, South Korea; Yonsei Univ, Dept Emergency Med, Wonju Coll Med, 20 Ilsan Ro, Wonju 26426, South Korea; Gachon Univ, Dept Med Educ, Coll Med, Incheon, South Korea; Dong A Univ, Dept Emergency Med, Coll Med, Busan, South Korea; Dong A Univ, Dept Med Educ, Coll Med, Busan, South Korea; Seoul Natl Univ, Bundang Hosp, Dept Emergency Med, Coll Med, Seoul, South Korea; Chonnam Natl Univ, Dept Emergency Med, Gwangju, South Korea; Chungnam Natl Univ Hosp, Dept Emergency Med, Daejeon, South Korea; Yonsei Univ, Wonju Coll Med, Dept Med Educ, 20 Ilsan Ro, Wonju 26426, South Korea; Wonju Severance Christian Hosp, Dept Emergency Med, Wonju, South Korea | Lee, Byung/M-2236-2018; Park, Kyung Hye/AFL-3938-2022; Kang, Hyun/AAE-7872-2020; 박, 귀화/KHZ-1779-2024; Lee, Dong Eun/HTN-4501-2023 | 57202299238; 54420209700; 56518563300; 57203725848; 54411205900; 36126257100; 56159113900; 55999334800 | khyun@yonsei.ac.kr;erdoc@yonsei.ac.kr; | JOURNAL OF KOREAN MEDICAL SCIENCE | J KOREAN MED SCI | 1011-8934 | 1598-6357 | 36 | 49 | SCIE | MEDICINE, GENERAL & INTERNAL | 2021 | 5.354 | 27.6 | 0.23 | 2025-07-30 | 2 | 2 | Brain Death; Tissue and Organ Procurement; Organ Transplantation; Emergency Medicine | DONORS; CARE | Brain Death; Emergency Medicine; Organ Transplantation; Tissue and Organ Procurement | Adult; Attitude of Health Personnel; Cross-Sectional Studies; Female; Health Knowledge, Attitudes, Practice; Humans; Male; Middle Aged; Physicians; Surveys and Questionnaires; Tissue and Organ Procurement; adult; attitude to health; cross-sectional study; female; health personnel attitude; human; male; middle aged; physician; psychology; questionnaire; transplantation | English | 2021 | 2021-12-20 | 10.3346/jkms.2021.36.e329 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Review | ARCO Consensus on the Pathogenesis of Non-traumatic Osteonecrosis of the Femoral Head | Osteonecrosis of the femoral head (ONFH) is a devastating disease frequently leading to femoral head collapse and hip arthritis. Specifically, non-traumatic ONFH primarily affects young and middle-aged adults. Although compromised local circulation of the femoral head seems to be pathognomonic for the disease, the pathogenesis is perplexing and continues to be an area of scrutiny and research. Comprehension of the pathogenesis is of crucial importance for developing and guiding treatments for the disease. Therefore, we provide an up-to-date consensus on the pathogenesis of non-traumatic ONFH. | Cui, Quanjun; Jo, Woo-Lam; Koo, Kyung-Hoi; Cheng, Edward Y.; Drescher, Wolf; Goodman, Stuart B.; Ha, Yong-Chan; Hernigou, Phillippe; Jones, Lynne C.; Kim, Shin-Yoon; Lee, Kyu Sang; Lee, Mel S.; Lee, Yun Jong; Mont, Michael A.; Sugano, Nobuhiko; Taliaferro, John; Yamamoto, Takuaki; Zhao, Dewei | Univ Virginia, Dept Orthopaed Surg, Sch Med, Charlottesville, VA USA; Catholic Univ Korea, Coll Med, Dept Orthopaed Surg, Seoul St Marys Hosp, 222 Banpo Daero, Seoul 06591, South Korea; Seoul Natl Univ, Dept Orthopaed Surg, Bundang Hosp, Seongnam, South Korea; Seoul Natl Univ, Med Coll, Seongnam, South Korea; Univ Minnesota, Dept Orthopaed Surg, Med Sch, Minneapolis, MN USA; RWTH Univ Hosp, Dept Orthoped Surg, Aachen, Germany; Stanford Univ, Dept Orthopaed Surg, Sch Med, Redwood City, CA USA; Chung Ang Univ, Dept Orthopaed Surg, Coll Med, Seoul, South Korea; Hop Henri Mondor, Creteil, France; Johns Hopkins Univ, Dept Orthopaed Surg, Sch Med, Baltimore, MD USA; Kyungpook Natl Univ, Grad Sch Med, Dept Orthoped Surg, Daegu, South Korea; Seoul Natl Univ, Dept Pathol, Bundang Hosp, Seongnam, South Korea; Kaohsiung Chang Gung Mem Hosp, Dept Orthopaed Surg, Kaohsiung, Taiwan; Seoul Natl Univ, Dept Internal Med, Bundang Hosp, Seongnam, Taiwan; Northwell Hlth, Dept Orthopaed Surg, Lenox Hill Hosp, New York, NY USA; Osaka Univ, Dept Orthopaed Surg, Grad Sch Med, Osaka, Japan; Fukuoka Univ, Fac Med, Dept Orthopaed Surg, Fukuoka, Japan; Dalian Univ, Dept Orthoped, Affiliated Zhongshan Hosp, Dalian, Peoples R China | ; Koo, Kyung-Hoi/D-7053-2012; Goodman, Stuart/AAZ-7499-2020; Kim, Soo/J-5411-2012; Zhao, Dewei/G-8369-2016 | 7103080108; 57040633000; 23488849400; 7201743350; 7004289286; 7402115472; 7102444576; 7005153893; 25625068200; 26663842900; 57189704116; 34971445900; 56584775600; 7005154075; 7101688414; 57222481259; 8069263600; 13104086400 | jis25@naver.com; | JOURNAL OF KOREAN MEDICAL SCIENCE | J KOREAN MED SCI | 1011-8934 | 1598-6357 | 36 | 10 | SCIE | MEDICINE, GENERAL & INTERNAL | 2021 | 5.354 | 27.6 | 7.11 | 2025-07-30 | 64 | 75 | Pathogenesis; Osteonecrosis; Osteonecrosis of the Femoral Head | CLINICAL IMPLICATIONS; BONE; HYPOFIBRINOLYSIS; NECROSIS; THROMBOPHILIA; BIOLOGY; GENE | Osteonecrosis; Osteonecrosis of the Femoral Head; Pathogenesis | Angiography; Consensus; Disease Progression; Femur Head; Femur Head Necrosis; Societies, Medical; angiography; consensus; disease exacerbation; femoral head; femur head necrosis; medical society; pathology; pathophysiology | English | 2021 | 2021-03-15 | 10.3346/jkms.2021.36.e65 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Can Environmental Pollutants Be a Factor Linking Obesity and COVID-19? | Lee, Duk-Hee | Kyungpook Natl Univ, Sch Med, Dept Prevent Med, 680 Gukchaebosang Ro, Daegu 41944, South Korea | 57211851121 | lee_dh@knu.ac.kr; | JOURNAL OF KOREAN MEDICAL SCIENCE | J KOREAN MED SCI | 1011-8934 | 1598-6357 | 36 | 43 | SCIE | MEDICINE, GENERAL & INTERNAL | 2021 | 5.354 | 27.6 | 0.11 | 2025-07-30 | 1 | 1 | PERSISTENT ORGANIC POLLUTANTS; ADIPOSE-TISSUE; POLYCHLORINATED-BIPHENYLS; IMMUNOTOXICITY; RISK; PESTICIDES; LIPOLYSIS | Air Pollutants; Air Pollution; COVID-19; Environmental Pollutants; Humans; Obesity; Pandemics; Particulate Matter; SARS-CoV-2; adverse event; air pollutant; air pollution; complication; human; obesity; pandemic; particulate matter; pathophysiology; pollutant | English | 2021 | 2021-11-08 | 10.3346/jkms.2021.36.e305 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||||
| ○ | ○ | Article | Clinical and Virologic Effectiveness of Remdesivir Treatment for Severe Coronavirus Disease 2019 (COVID-19) in Korea: a Nationwide Multicenter Retrospective Cohort Study | Background: Remdesivir is widely used for the treatment of coronavirus disease 2019 (COVID-19), but controversies regarding its efficacy still remain. Methods: A retrospective cohort study was conducted to evaluate the effect of remdesivir on clinical and virologic outcomes of severe COVID-19 patients from June to July 2020. Primary clinical endpoints included clinical recovery, additional mechanical ventilator (MV) support, and duration of oxygen or MV support. Viral load reduction by hospital day (HD) 15 was evaluated by calculating changes in cycle threshold (Ct) values. Results: A total of 86 severe COVID-19 patients were evaluated including 48 remdesivir-treated patients. Baseline characteristics were not significantly different between the two groups. Remdesivir was administered an average of 7.42 days from symptom onset. The proportions of clinical recovery of the remdesivir and supportive care group at HD 14 (56.3% and 39.5%) and HD 28 (87.5% and 78.9%) were not statistically different. The proportion of patients requiring MV support by HD 28 was significantly lower in the remdesivir group than in the supportive care group (22.9% vs. 44.7%, P= 0.032), and MV duration was significantly shorter in the remdesivir group (average, 1.97 vs. 5.37 days; P= 0.017). Analysis of upper respiratory tract specimens demonstrated that increases of Ct value from HD 1-5 to 11-15 were significantly greater in the remdesivir group than the supportive care group (average, 10.19 vs. 5.36; P= 0.007), and the slope of the Ct value increase was also significantly steeper in the remdesivir group (average, 5.10 vs. 2.68; P= 0.007). Conclusion: The remdesivir group showed clinical and virologic benefit in terms of MV requirement and viral load reduction, supporting remdesivir treatment for severe COVID-19. | Joo, Eun-Jeong; Ko, Jae-Hoon; Kim, Seong Eun; Kang, Seung-Ji; Baek, Ji Hyeon; Heo, Eun Young; Shi, Hye Jin; Eom, Joong Sik; Choe, Pyoeng Gyun; Bae, Seongman; Ra, Sang Hyun; Kim, Da Young; Kim, Baek-Nam; Kang, Yu Min; Kim, Ji Yeon; Chung, Jin-Won; Chang, Hyun-Ha; Bae, Sohyun; Cheon, Shinhyea; Park, Yoonseon; Choi, Heun; Lee, Eunjung; Lee, Bo Young; Park, Jung Wan; Sohn, Yujin; Heo, Jung Yeon; Kim, Sung-Han; Peck, Kyong Ran | Sungkyunkwan Univ, Kangbuk Samsung Hosp, Dept Med, Div Infect Dis,Sch Med, Seoul, South Korea; Sungkyunkwan Univ, Samsung Med Ctr, Dept Med, Div Infect Dis,Sch Med, 81 Irwon Ro, Seoul 06351, South Korea; Chonnam Natl Univ Hosp, Dept Internal Med, Div Infect Dis, Gwangju, South Korea; Inha Univ, Dept Internal Med, Sch Med, Incheon, South Korea; Seoul Natl Univ, Dept Internal Med, Div Pulm & Crit Care, Boramae Med Ctr,Seoul Metropolitan Govt, Seoul, South Korea; Gachon Univ, Gil Med Ctr, Dept Internal Med, Div Infect Dis,Coll Med, Incheon, South Korea; Seoul Natl Univ, Dept Internal Med, Coll Med, Seoul, South Korea; Univ Ulsan, Asan Med Ctr, Dept Infect Dis, Coll Med, 88 Olymp Ro 43 Gil, Seoul 05505, South Korea; Chosun Univ, Sch Med, Dept Internal Med, Gwangju, South Korea; Inje Univ, Dept Internal Med, Sanggye Paik Hosp, Seoul, South Korea; Hanyang Univ, Myongji Hosp, Dept Infect Dis, Coll Med, Goyang, South Korea; Seongnam Citizens Med Ctr, Dept Med, Div Infect Dis, Seongnam, South Korea; Chung Ang Univ, Chung Ang Univ Hosp, Dept Internal Med, Div Infect Dis,Coll Med, Seoul, South Korea; Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu, South Korea; Chungnam Natl Univ, Dept Internal Med, Div Infect Dis, Sch Med, Daejeon, South Korea; Ilsan Hosp, Dept Infect Dis, Natl Hlth Insurance Serv, Goyang, South Korea; Soonchunhyang Univ, Seoul Hosp, Dept Internal Med, Coll Med, Cheonan, South Korea; Soonchunhyang Univ, Coll Med, Dept Internal Med, Cheonan Hosp, Cheonan, South Korea; Yonsei Univ, Severance Hosp, Dept Internal Med, Div Infect Dis,Coll Med, Seoul, South Korea; Ajou Univ, Dept Infect Dis, Sch Med, Suwon, South Korea | Peck, Kyong Ran/AGV-5205-2022; Kim, Baek-Nam/AGO-0326-2022; Kim, Seog/J-5403-2012; Kim, Sang Hyuk/AFE-5646-2022 | 57246553800; 55804188300; 57226683401; 37072777000; 26644740900; 55640179600; 57204566540; 8312280800; 15070608400; 57189690904; 57212114516; 57222540199; 7501566646; 55267459000; 59910950100; 54892853700; 7407521688; 57219699506; 54790749100; 55494377800; 55940398500; 57203206523; 57215105497; 57192071755; 57216369805; 24587525000; 55133790400; 55664295200 | kimsunghanmd@hotmail.com;krpeck@skku.edu; | JOURNAL OF KOREAN MEDICAL SCIENCE | J KOREAN MED SCI | 1011-8934 | 1598-6357 | 36 | 11 | SCIE | MEDICINE, GENERAL & INTERNAL | 2021 | 5.354 | 27.6 | 2.87 | 2025-07-30 | 28 | 26 | Remdesivir; Severe; COVID-19; Clinical; Virologic | CONVALESCENT PLASMA THERAPY; ACUTE RESPIRATORY SYNDROME; RIBAVIRIN | Clinical; COVID-19; Remdesivir; Severe; Virologic | Adenosine Monophosphate; Aged; Aged, 80 and over; Alanine; Antiviral Agents; COVID-19; Female; Humans; Male; Middle Aged; Real-Time Polymerase Chain Reaction; Respiration, Artificial; Retrospective Studies; SARS-CoV-2; Viral Load; adenosine phosphate; alanine; antivirus agent; remdesivir; aged; artificial ventilation; clinical trial; drug therapy; female; human; male; middle aged; multicenter study; real time polymerase chain reaction; retrospective study; very elderly; virology; virus load | English | 2021 | 2021-03-22 | 10.3346/jkms.2021.36.e83 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Clinical Characteristics and Outcomes of COVID-19 Cohort Patients in Daegu Metropolitan City Outbreak in 2020 | Background: A coronavirus disease 2019 (COVID-19) outbreak started in February 2020 and was controlled at the end of March 2020 in Daegu, the epicenter of the coronavirus outbreak in Korea. The aim of this study was to describe the clinical course and outcomes of patients with COVID-19 in Daegu. Methods: In collaboration with Daegu Metropolitan City and Korean Center for Diseases Control, we conducted a retrospective, multicenter cohort study. Demographic, clinical, treatment, and laboratory data, including viral RNA detection, were obtained from the electronic medical records and cohort database and compared between survivors and non-survivors. We used univariate and multi-variable logistic regression methods and Cox regression model and performed Kaplan-Meier analysis to determine the risk factors associated with the 28-day mortality and release from isolation among the patients. Results: In this study, 7,057 laboratory-confirmed patients with COVID-19 (total cohort) who had been diagnosed from February 18 to July 10, 2020 were included. Of the total cohort, 5,467 were asymptomatic to mild patients (77.4%) (asymptomatic 30.6% and mild 46.8%), 985 moderate (14.0%), 380 severe (5.4%), and 225 critical (3.2%). The mortality of the patients was 2.5% (179/7,057). The Cox regression hazard model for the patients with available clinical information (core cohort) (n = 2,254) showed the risk factors for 28-day mortality: age > 70 (hazard ratio [HR], 4.219, P= 0.002), need for O-2 supply at admission (HR, 2.995; P= 0.001), fever (> 37.5 degrees C) (HR, 2.808; P= 0.001), diabetes (HR, 2.119; P = 0.008), cancer (HR, 3.043; P= 0.011), dementia (HR, 5.252; P= 0.008), neurological disease (HR, 2.084; P= 0.039), heart failure (HR, 3.234; P= 0.012), and hypertension (HR, 2.160; P= 0.017). The median duration for release from isolation was 33 days (interquartile range, 24.0-46.0) in survivors. The Cox proportional hazard model for the long duration of isolation included severity, age > 70, and dementia. Conclusion: Overall, asymptomatic to mild patients were approximately 77% of the total cohort (asymptomatic, 30.6%). The case fatality rate was 2.5%. Risk factors, including older age, need for O-2 supply, dementia, and neurological disorder at admission, could help clinicians to identify COVID-19 patients with poor prognosis at an early stage. | Kim, Shin-Woo; Kim, Seung-Mee; Kim, Yu Kyung; Kim, Jong-yeon; Lee, Yu-Mi; Kim, Bong-Ok; Hwangbo, Suhyun; Park, Taesung | Kyungpook Natl Univ, Sch Med, Dept Internal Med, 130 Dongdeok Ro, Daegu 41944, South Korea; Daegu Med Ctr, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Clin Pathol, Daegu, South Korea; Kyungpook Natl Univ Hosp, Dept Publ Hlth, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Prevent Med, Daegu, South Korea; Korea Workers Compensat & Welf Serv Daegu Hosp, Daegu, South Korea; Seoul Natl Univ, Interdisciplinary Program Bioinformat, Seoul, South Korea; Seoul Natl Univ, Dept Stat, Coll Nat Sci, Seoul, South Korea | ; Kim, Sun/G-3451-2013; Kim, Young-Il/ISS-7678-2023 | 8710731500; 57221518120; 9237571900; 58382951500; 57075191600; 35324778400; 57208262466; 34668299500 | ksw2kms@knu.ac.kr; | JOURNAL OF KOREAN MEDICAL SCIENCE | J KOREAN MED SCI | 1011-8934 | 1598-6357 | 36 | 1 | SCIE | MEDICINE, GENERAL & INTERNAL | 2021 | 5.354 | 27.6 | 5.39 | 2025-07-30 | 48 | 49 | COVID-19; Outcome; Outbreak; Mortality; Case Fatality Rate | CORONAVIRUS DISEASE 2019 | Case Fatality Rate; COVID-19; Mortality; Outbreak; Outcome | Adolescent; Adult; Aged; Aged, 80 and over; Asymptomatic Infections; Child; Child, Preschool; COVID-19; Disease Outbreaks; Female; Humans; Infant; Infant, Newborn; Male; Middle Aged; Proportional Hazards Models; Republic of Korea; Retrospective Studies; SARS-CoV-2; Young Adult; adolescent; adult; aged; asymptomatic infection; child; clinical trial; epidemic; female; human; infant; male; middle aged; mortality; multicenter study; newborn; preschool child; proportional hazards model; retrospective study; South Korea; very elderly; young adult | English | 2021 | 2021-01-04 | 10.3346/jkms.2021.36.e12 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Development and Verification of an Internet Game Literacy Scale | Background: Education on internet games for parents and internet game literacy are needed to prevent problematic internet game playing in Korea. We created an 18-item Internet Game Literacy Scale (IGLS). It is a valuable tool for assessing the positive and negative aspects of internet game play. We aimed to determine the validity of the IGLS and the cut-off for the tendency for internet gameplay. Methods: An online research company gathered data from 300 participants. Factor analysis, including Cronbach's a and consistency coefficient, exploratory factor analysis, and confirmatory factor analysis were conducted to verify the 18 items of the IGLS. Additionally, a K-means cluster analysis was performed to determine the cut-off values for positive and negative IGLS scores. Results: The 18 items of the IGLS were proven to be reliable, as evidenced by a high Cronbach's alpha (alpha = 0.892). The Kaiser-Meyer-Olkin measure of sampling adequacy was 0.903, and Bartlett's test of sphericity was good (chi(2) = 1,623.314, P 0.4. In the analysis of the validity of the 18-item IGLS with confirmatory factor analysis (CFA) (maximum likelihood estimation, with an oblique method), the fit indices of the standard three-factor model reached acceptable standards. The cut-off point of the total score between the low positive and average positive groups was 23, and the cut-off point of the total score between the average positive and high positive groups was 30. The cut-off point of the total score between the low negative and the average negative groups was 24. The cut-off point of the total score between the average negative group and the high negative group was 32. Conclusion: The study assessed the reliability and validity of the IGLS and suggested a cut-off for low, average, and high Internet game literacy degree with 300 Korean adults aged 21-49 years. The current results suggest that the IGLS has good internal consistency and a proper cut-off for positive and negative internet game literacy degrees. | Chung, UnSun; Kim, Soyeon; Jin, Jaechan; Han, Doug Hyun | Kyungpook Natl Univ, Sch Med, Dept Psychiat, Daegu, South Korea; Chung Ang Univ, Dept Psychiat, Sch Med, 84 Heukseok Ro, Seoul 06974, South Korea; Soongsil Univ, Sch Social Welf, Seoul, South Korea | Jin, Jaechan/JYP-6192-2024 | 24477437300; 57228323200; 57215089447; 8774251600 | hduk70@gmail.com; | JOURNAL OF KOREAN MEDICAL SCIENCE | J KOREAN MED SCI | 1011-8934 | 1598-6357 | 36 | 35 | SCIE | MEDICINE, GENERAL & INTERNAL | 2021 | 5.354 | 27.6 | 0.34 | 2025-07-30 | 4 | 4 | Internet Game Literacy Scales; Exploratory Factor Analysis; Confirmatory Factor Analysis; K-Means Cluster Analysis | CONFIRMATORY FACTOR-ANALYSIS; OF-FIT INDEXES; ADDICTION; PREVENTION; PARENTS | Confirmatory Factor Analysis; Exploratory Factor Analysis; Internet Game Literacy Scales; K-Means Cluster Analysis | Adult; Female; Humans; Internet; Male; Middle Aged; Parents; Perception; Psychometrics; Republic of Korea; Surveys and Questionnaires; Video Games; Young Adult; adult; child parent relation; female; human; Internet; male; middle aged; perception; procedures; psychology; psychometry; questionnaire; South Korea; video game; young adult | English | 2021 | 2021-09-06 | 10.3346/jkms.2021.36.e216 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Discrepancy between Cytology and Histology in Cervical Cancer Screening: a Multicenter Retrospective Study (KGOG 1040) | Background: Cervical cancer is the fourth common cancer in women worldwide. The Papanicolau test is the primary screening procedure to detect abnormal cervical cells. Colposcopy is the main procedure for discriminating high-grade cervical lesions. The study aimed at clarifying the discrepancy between cervical cytology and colposcopic biopsy histology as well as confounding factors. Methods: Eligible patients visited thirteen tertiary hospitals for colposcopic biopsy following cervical cytology and human papillomavirus (HPV) genotypes between January and December 2018. Baseline characteristics including age, body mass index (BMI), and parity were collected. Results: In our study, 3,798 eligible patients were included. Mean age of patients was 42.7 (19-88) years and mean BMI was 22.5 (16.9-34.1) kg/m(2). The referred cervical cytologic findings consisted of 495 normal, 1,390 atypical squamous cells of undetermined significance, 380 atypical squamous cells cannot exclude high-grade squamous intraepithelial lesion, 792 low-grade squamous intraepithelial lesion, 593 high-grade squamous intraepithelial lesion, 79 atypical glandular cells, 46 squamous cell carcinoma, and 23 adenocarcinoma. HPV-positive findings were found in 3,008 (79.2%) patients and were not detected in 914 (24.1%) cases. The risk of unexpected low-grade lesions from histology was higher in patients > 45 years (odds ratio [OR], 2.137; 95% confidence intervals [CIs], 1.475-3.096). In contrast, the risk of unexpected high-grade lesions from colposcopic biopsy was lower in patients >= 45 years (OR, 0.530; 95% CI, 0.367-0.747) and HPV 16/18 infection was higher than other HPV (OR, 1.848; 95% CI, 1.385-2.469). Conclusion: Age and HPV genotypes were responsible for the discrepancies between cytology and histology. Precautions should be taken for women over the age of 45 in triage for colposcopy in order to avoid unnecessary testing. | Ouh, Yung-Taek; Park, Ji Jeong; Kang, Minjoo; Kim, Miseon; Song, Jae Yun; Shin, So Jin; Shim, Seung-Hyuk; Yoo, Heon Jong; Lee, Maria; Lee, Sung-Jong; Shin, Whan; Chong, Gun Oh; Choi, Min Chul; Choi, Chel Hun; Min, Kyung-Jin | Korea Univ, Dept Obstet & Gynecol, Guro Hosp, Seoul, South Korea; Kangwon Natl Univ, Grad Sch Med, Dept Obstet & Gynecol, Chunchon, South Korea; Natl Evidence Based Healthcare Collaborating Agcy, Seoul, South Korea; CHA Gangnam Med Ctr, Dept Obstet & Gynecol, Seoul, South Korea; Korea Univ, Dept Obstet & Gynecol, Anam Hosp, Seoul, South Korea; Keimyung Univ, Dept Obstet & Gynecol, Dongsan Med Ctr, Daegu, South Korea; Konkuk Univ Hosp, Dept Obstet & Gynecol, Seoul, South Korea; Chungnam Natl Univ Hosp, Dept Obstet & Gynecol, Daejeon, South Korea; Seoul Natl Univ Hosp, Dept Obstet & Gynecol, Seoul, South Korea; Catholic Univ Korea, Coll Med, Dept Obstet & Gynecol, Seoul St Marys Hosp, Seoul, South Korea; Yonsei Univ, Dept Obstet & Gynecol, Severance Hosp, Seoul, South Korea; Dankook Univ, Dankook Univ Hosp, Dept Obstet & Gynecol, Cheonan, South Korea; Kyungpook Natl Univ, Dept Obstet & Gynecol, Chilgok Hosp, Daegu, South Korea; CHA Bundang Med Ctr, Comprehens Gynecol Canc Ctr, Seongnam, South Korea; Samsung Med Ctr, Dept Obstet & Gynecol, Seoul, South Korea; Korea Univ, Dept Obstet & Gynecol, Ansan Hosp, 123 Jeokgeum Ro, Ansan 15355, South Korea | Ouh, Yung-Taek/HNC-0103-2023; Min, Kyung/AAK-8261-2020; Lee, Maria/AGX-4688-2022 | 55387186000; 57224993584; 57208156856; 57191902386; 19536667200; 23006860000; 55652813100; 39362841900; 36760964100; 37056885000; 57216374977; 23099068000; 57192236842; 11939248200; 55650428400 | mikji78@gmail.com; | JOURNAL OF KOREAN MEDICAL SCIENCE | J KOREAN MED SCI | 1011-8934 | 1598-6357 | 36 | 24 | SCIE | MEDICINE, GENERAL & INTERNAL | 2021 | 5.354 | 27.6 | 0.8 | 2025-07-30 | 9 | 9 | HPV; Cervical Cytology; Colposcopy; Discrepancy; Histology | II HPV HR; WOMEN; MANAGEMENT; COLPOSCOPY; LESIONS; GUIDELINES; QUALITY | Cervical Cytology; Colposcopy; Discrepancy; Histology; HPV | Adult; Aged; Aged, 80 and over; Biopsy; Cervical Intraepithelial Neoplasia; Cervix Uteri; Colposcopy; DNA, Viral; Early Detection of Cancer; Female; Human papillomavirus 16; Human papillomavirus 18; Humans; Mass Screening; Middle Aged; Predictive Value of Tests; Retrospective Studies; Sensitivity and Specificity; Uterine Cervical Neoplasms; Vaginal Smears; virus DNA; adult; aged; biopsy; clinical trial; colposcopy; early cancer diagnosis; female; genetics; human; Human papillomavirus type 16; Human papillomavirus type 18; mass screening; middle aged; multicenter study; pathology; predictive value; procedures; retrospective study; sensitivity and specificity; uterine cervix; uterine cervix carcinoma in situ; uterine cervix tumor; vagina smear; very elderly; virology | English | 2021 | 2021-06-21 | 10.3346/jkms.2021.36.e164 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Effect of Sedatives on In-hospital and Long-term Mortality of Critically Ill Patients Requiring Extended Mechanical Ventilation for ≥ 48 Hours | Background: The purpose of this study was to assess the correlation between sedatives and mortality in critically ill patients who required mechanical ventilation (MV) for >= 48 hours from 2008 to 2016. Methods: We conducted a nationwide retrospective cohort study using population-based healthcare reimbursement claims database. Data from adult patients (aged >= 18) who underwent MV for >= 48 hours between 2008 and 2016 were identified and extracted from the National Health Insurance Service database. The benzodiazepine group consisted of patients who were administered benzodiazepines for sedation during MV. All other patients were assigned to the non-benzodiazepine group. Results: A total of 158,712 patients requiring MV for >= 48 hours were admitted in 55 centers in Korea from 2008 to 2016. The benzodiazepine group had significantly higher in-hospital and one-year mortality compared to the non-benzodiazepine group (37.0% vs. 34.3%, 55.0% vs. 54.4%, respectively). Benzodiazepine use decreased from 2008 to 2016, after adjusting for age, sex, and mean Elixhauser comorbidity index in the Poisson regression analysis (incidence rate ratio, 0.968; 95% confident interval, 0.954-0.983; P = 48 hour, the use of benzodiazepines for sedation, older age, and chronic kidney disease were associated with higher in-hospital mortality and one-year mortality. Further studies are needed to evaluate the impact of benzodiazepines on the mortality in elderly patients with chronic kidney disease requiring MV for >= 48 hours. | Lee, Hannah; Choi, Seongmi; Jang, Eun Jin; Lee, Juhee; Kim, Dalho; Yoo, Seokha; Oh, Seung-Young; Ryu, Ho Geol | Seoul Natl Univ, Seoul Natl Univ Hosp, Dept Anesthesiol & Pain Med, Coll Med, 101 Daehak Ro, Seoul 03080, South Korea; Hlth Insurance Policy Res Inst, Natl Hlth Insurance Serv, Wonju, South Korea; Andong Natl Univ, Dept Informat Stat, Andong, South Korea; Kyungpook Natl Univ, Dept Stat, Daegu, South Korea; Seoul Natl Univ, Seoul Natl Univ Hosp, Dept Surg, Coll Med, Seoul, South Korea | ; Ryu, Ho/J-5463-2012; Yoo, Seokha/H-1638-2018 | 55634905800; 57211676692; 37861741600; 57210897006; 57198636658; 55883558900; 55930541200; 7202277246 | hogeol@gmail.com; | JOURNAL OF KOREAN MEDICAL SCIENCE | J KOREAN MED SCI | 1011-8934 | 1598-6357 | 36 | 34 | SCIE | MEDICINE, GENERAL & INTERNAL | 2021 | 5.354 | 27.6 | 0.8 | 2025-07-30 | 6 | 8 | Sedative; Dexmedetomidine; Mortality; Benzodiazepine; Propofol | INTENSIVE-CARE-UNIT; CLINICAL-PRACTICE GUIDELINES; ADULT PATIENTS; DELIRIUM; PREVENTION; PROPOFOL; PROTOCOL; OUTCOMES; BENZODIAZEPINES; DEXMEDETOMIDINE | Benzodiazepine; Dexmedetomidine; Mortality; Propofol; Sedative | Aged; Aged, 80 and over; Benzodiazepines; Critical Care; Critical Illness; Dexmedetomidine; Female; Hospital Mortality; Humans; Hypnotics and Sedatives; Intensive Care Units; Length of Stay; Male; Middle Aged; Propofol; Republic of Korea; Respiration, Artificial; Retrospective Studies; Time Factors; benzodiazepine derivative; dexmedetomidine; hypnotic sedative agent; propofol; aged; artificial ventilation; critical illness; female; hospital mortality; human; intensive care; intensive care unit; length of stay; male; middle aged; mortality; retrospective study; South Korea; time factor; very elderly | English | 2021 | 2021-08-30 | 10.3346/jkms.2021.36.e221 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Etiological Distribution and Morphological Patterns of Granulomatous Pleurisy in a Tuberculosis-prevalent Country | The cause of epithelioid granulomatous inflammation varies widely depending on the affected organ, geographic region, and whether the granulomas morphologically contain necrosis. Compared with other organs, the etiological distribution and morphological patterns of pleural epithelioid granulomas have rarely been investigated. We evaluated the final etiologies and morphological patterns of pleural epithelioid granulomatous inflammation in a tuberculosis (TB)-prevalent country. Of 83 patients with pleural granulomas, 50 (60.2%) had confirmed TB pleurisy (TB-P) and 29 (34.9%) had probable TBP. Four patients (4.8%) with non-TB-P were diagnosed. With the exception of microbiological results, there was no significant difference in clinical characteristics and granuloma patterns between the confirmed TB-P and non-TB-P groups, or between patients with confirmed and probable TB-Ps. These findings suggest that most pleural granulomatous inflammation (95.2%) was attributable to TB-P in TB-endemic areas and that the granuloma patterns contributed little to the prediction of final diagnosis compared with other organs. | Lee, Jaehee; Park, Sunji; Park, Ji Eun; Choi, Sun Ha; Seo, Hyewon; Yoo, Seung Soo; Lee, Shin Yup; Kim, Yu Kyung; Cha, Seung-Ick; Park, Jae Yong; Park, Tae In; Kim, Chang Ho | Kyungpook Natl Univ, Sch Med, Dept Internal Med, 680 Gukchaebosang Ro, Daegu 41944, South Korea; Kyungpook Natl Univ, Sch Med, Dept Clin Pathol, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Pathol, 680 Gukchaebosang Ro, Daegu 41944, South Korea | ; Lee, Jaehee/S-1697-2018; Choi, Sun Ha/HPD-7234-2023; Kim, Young-Il/ISS-7678-2023; Lee, Yoojin/AAB-9799-2022 | 13805476000; 57210251534; 57195437358; 57199723585; 55612130200; 56479781600; 49863712700; 9237571900; 35227126400; 58360293800; 7401801814; 7409873555 | tipark@knu.ac.kr;kimch@knu.ac.kr; | JOURNAL OF KOREAN MEDICAL SCIENCE | J KOREAN MED SCI | 1011-8934 | 1598-6357 | 36 | 1 | SCIE | MEDICINE, GENERAL & INTERNAL | 2021 | 5.354 | 27.6 | 0.57 | 2025-07-30 | 5 | 6 | Granuloma; Necrosis; Pleura; Tuberculosis | CLINICAL-FEATURES; INFLAMMATION; EFFUSIONS | Granuloma; Necrosis; Pleura; Tuberculosis | Adenosine Deaminase; Adult; Algorithms; DNA, Bacterial; Female; Granuloma; Humans; Male; Middle Aged; Mycobacterium tuberculosis; Pleura; Pleurisy; Tuberculosis; adenosine deaminase; bacterial DNA; adult; algorithm; complication; female; genetics; granuloma; human; isolation and purification; male; metabolism; microbiology; middle aged; Mycobacterium tuberculosis; pathology; pleura; pleurisy; tuberculosis | English | 2021 | 2021-01-04 | 10.3346/jkms.2021.36.e10 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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