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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Article | Proteomic analysis of fipronil-induced molecular defects in spermatozoa | The phenylpyrazole insecticide fipronil has wide-ranging applications from agriculture to public health to control undesirable organisms. However, several studies have reported the residual environmental hazards of fipronil and demonstrated its harmful effects even in mammalian reproduction. Therefore, this study was conducted to demonstrate the mode of action of fipronil on mouse spermatozoa. We treated fipronil to spermatozoa and performed comprehensive function evaluations. Moreover, proteomic analyses were conducted to identify the alteration of protein expression levels in spermatozoa. Most of sperm motility and kinematic parameters and intracellular ATP levels were diminished, and the spontaneous acrosome reaction was promoted after treatment with fipronil. Proteomic analyses revealed altered expression levels of 14 proteins after treatment. These proteins have been reported to be associated with sperm-specific pathways, prominently the cytoskeleton of the sperm, "9 + 2" axoneme composition, metabolism, and fertility. Collectively, our results showed that fipronil alters sperm functional-related proteins and therefore influences male fertility. This study elucidates the possible reproductive toxic hazards associated with male infertility through aberrant suppression of sperm proteins. | Bae, Jeong-Won; Kwon, Woo-Sung | Kyungpook Natl Univ, Dept Anim Sci & Biotechnol, Sangju, South Korea; Kyungpook Natl Univ, Res Inst Innovat Anim Sci, Sangju, South Korea | Kwon, Woo-Sung/J-6731-2019; Bae, Jeong-Won/AAH-4932-2021; Kwon, Woo-Sung/J-4391-2014 | 57211231093; 54383715800 | wskwon@knu.ac.kr; | SCIENTIFIC REPORTS | SCI REP-UK | 2045-2322 | 14 | 1 | SCIE | MULTIDISCIPLINARY SCIENCES | 2024 | 3.9 | 18.1 | 0.41 | 2025-05-07 | 1 | 1 | Pesticide-affected spermatozoa; Differentially expressed proteins; Male infertility | SPERM-MOTILITY; PROTEIN; IDENTIFICATION; CHAPERONIN-10; FERTILITY; EXPOSURE; DYNEIN; ACTIN | Differentially expressed proteins; Male infertility; Pesticide-affected spermatozoa | Animals; Male; Mammals; Mice; Proteins; Proteomics; Pyrazoles; Semen; Sperm Motility; Spermatozoa; fipronil; protein; pyrazole derivative; animal; male; mammal; metabolism; mouse; proteomics; sperm; spermatozoon; spermatozoon motility | English | 2024 | 2024-04-01 | 10.1038/s41598-024-57876-4 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Repositioned versus exchanged flanged intraocular lens fixation for intraocular lens dislocation | This study aimed to compare the outcomes of flanged intraocular lens (IOL) fixation with new IOL exchange after dislocated IOL removal and repositioned dislocated IOL in patients with IOL dislocation. Eighty-nine eyes that underwent flanged IOL fixation were retrospectively included, with 51 eyes in the exchanged IOL group and 38 eyes in the repositioned IOL group. In both groups, best-corrected visual acuity (BCVA) improved at 1, 3, 6, and 12 months postoperatively and did not differ between the two groups at any of these time points. However, at 1 week postoperatively, BCVA in the repositioned IOL group improved compared with baseline, whereas that in the exchanged IOL group did not. Moreover, there were lesser changes in the corneal endothelial cell density (ECD) and corneal astigmatism in the repositioned IOL group than in the exchanged IOL group. The IOL positions, including IOL tilt and IOL decentration, were not different between the groups. Flanged IOL fixation with new IOL exchange and with repositioned dislocated IOL for patients with IOL dislocation had similar visual outcomes and IOL position. However, the latter had a smaller corneal ECD decrease and astigmatic change. This technique was effective in treating IOL dislocation while minimizing corneal injury. | Kang, Yong Koo; Park, Dong Ho; Ryu, Gahyung; Kim, Hong Kyun; Kim, Dong Hyun; Do, Jae Rock | Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Ophthalmol, 130 Dongdeok Ro, Daegu 41944, South Korea; Nune Eye Hosp, Seoul, South Korea | Kim, Hong Kyun/ITT-7758-2023; KANG, YONG KOO/IVH-8723-2023; Kim, Dong Hyun/LDT-2672-2024 | 57204703736; 36676632900; 58941163300; 57218260940; 58941163400; 58600232100 | doojr7@gmail.com; | SCIENTIFIC REPORTS | SCI REP-UK | 2045-2322 | 14 | 1 | SCIE | MULTIDISCIPLINARY SCIENCES | 2024 | 3.9 | 18.1 | 0.82 | 2025-05-07 | 3 | 2 | IMPLANTATION; ABSENCE | Humans; Lens Implantation, Intraocular; Lens Subluxation; Lenses, Intraocular; Postoperative Complications; Retrospective Studies; Suture Techniques; Visual Acuity; human; lens implantation; lens subluxation; postoperative complication; procedures; retrospective study; suture technique; visual acuity | English | 2024 | 2024-03-14 | 10.1038/s41598-024-54694-6 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Correction | Repositioned versus exchanged flanged intraocular lens fixation for intraocular lens dislocation (vol 14, 6181, 2024) | Kang, Yong Koo; Park, Dong Ho; Ryu, Gahyung; Kim, Hong Kyun; Kim, Dong Hyun; Do, Jae Rock | Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Ophthalmol, 130 Dongdeok Ro, Daegu 41944, South Korea; Nune Eye Hosp, Seoul, South Korea | Kim, Hong Kyun/ITT-7758-2023; Kim, Dong Hyun/LDT-2672-2024; KANG, YONG KOO/IVH-8723-2023 | 57204703736; 36676632900; 58941163300; 57218260940; 58941163400; 58600232100 | doojr7@gmail.com; | SCIENTIFIC REPORTS | SCI REP-UK | 2045-2322 | 14 | 1 | SCIE | MULTIDISCIPLINARY SCIENCES | 2024 | 3.9 | 18.1 | 0 | 2025-05-07 | 0 | 0 | CASE-CROSSOVER; SARS-COV-2 INFECTION; SPONTANEOUS-ABORTION; VACCINE SAFETY; BIRTH-DEFECTS; PREGNANCY; COVID-19; STRATEGIES; WOMEN; RISK | diagnosis; erratum; human; lens implant; lens luxation; lens subluxation | English | 2024 | 2024-03-27 | 10.1038/s41598-024-58105-8 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||||
| ○ | ○ | Article | Screening patients requiring secondary lumbar surgery for degenerative lumbar spine diseases: a nationwide sample cohort study | This study aims to identify healthcare costs indicators predicting secondary surgery for degenerative lumbar spine disease (DLSD), which significantly impacts healthcare budgets. Analyzing data from the National Health Insurance Service-National Sample Cohort (NHIS-NSC) database of Republic of Korea (ROK), the study included 3881 patients who had surgery for lumbar disc herniation (LDH), lumbar spinal stenosis without spondylolisthesis (LSS without SPL), lumbar spinal stenosis with spondylolisthesis (LSS with SPL), and spondylolysis (SP) from 2006 to 2008. Patients were categorized into two groups: those undergoing secondary surgery (S-group) and those not (NS-group). Surgical and interim costs were compared, with S-group having higher secondary surgery costs ($1829.59 vs $1618.40 in NS-group, P = 0.002) and higher interim costs ($30.03; 1.86% of initial surgery costs vs $16.09; 0.99% of initial surgery costs in NS-group, P < 0.0001). The same trend was observed in LDH, LSS without SPL, and LSS with SPL (P < 0.0001). Monitoring interim costs trends post-initial surgery can effectively identify patients requiring secondary surgery. | Park, Hangeul; Lee, Juhee; Choi, Yunhee; Kim, Jun-Hoe; Kim, Sum; Kim, Young-Rak; Lee, Chang-Hyun; Park, Sung Bae; Kim, Kyoung-Tae; Rhee, John M.; Kim, Chi Heon | Seoul Natl Univ Hosp, Dept Neurosurg, 101 Daehak ro, Seoul 03080, South Korea; Seoul Natl Univ Hosp, Med Res Collaborating Ctr, Div Med Stat, 101 Daehak ro, Seoul 03080, South Korea; Seoul Natl Univ, Dept Neurosurg, Coll Med, 103 Daehak Ro, Seoul 03080, South Korea; Seoul Natl Univ, Boramae Med Ctr, Dept Neurosurg, Boramae Hosp, 20,Boramae ro 5 gil, Seoul 07061, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Neurosurg, Daegu, South Korea; Emory Univ, Dept Orthopaed Surg, Sch Med, Atlanta, GA 30322 USA; Seoul Natl Univ, Dept Med Device Dev, Coll Med, 103 Daehak ro, Seoul 03080, South Korea | Kim, Chi/J-6536-2019; Choi, You-Jung/AFR-4193-2022 | 57221731362; 57204073070; 7404777879; 57854370000; 58609171200; 57222335356; 56942572100; 45261436700; 57201369790; 7202839338; 35145892000 | chiheon1@snu.ac.kr; | SCIENTIFIC REPORTS | SCI REP-UK | 2045-2322 | 14 | 1 | SCIE | MULTIDISCIPLINARY SCIENCES | 2024 | 3.9 | 18.1 | 0 | 2025-05-07 | 0 | 0 | LOW-BACK-PAIN; REOPERATION RATE; RISK-FACTORS; ADJACENT SEGMENT; STENOSIS; OUTCOMES; FUSION; SPONDYLOLISTHESIS; DECOMPRESSION; BURDEN | Cohort Studies; Humans; Intervertebral Disc Displacement; Lumbar Vertebrae; Spinal Stenosis; Spondylolisthesis; Treatment Outcome; cohort analysis; human; intervertebral disk hernia; lumbar vertebra; spondylolisthesis; treatment outcome; vertebral canal stenosis | English | 2024 | 2024-01-14 | 10.1038/s41598-024-51861-7 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Solution-processed NO2 gas sensor based on poly(3-hexylthiophene)-doped PbS quantum dots operable at room temperature | The global industrial development and increase in the number of transportation vehicles, such as automobiles and ships, have led to a steady increase in the issues related to greenhouse gas emissions. NO2 is a greenhouse gas emitted in large quantities from automobiles and factories, and its emission is unavoidable in the modern world. Therefore, a sensor capable of precise detection of NO2 is required. The most commonly reported types of NO2 sensors are those based on metal oxides. However, their operation at room temperature is impossible owing to their high-temperature operating characteristics, and therefore, a heater must be designed inside or installed outside the sensor for heating. Meanwhile, NO2 sensors based on PbS quantum dots (QDs) are advantageous as they can operate at room temperature and can be easily manufactured through a solution process rather than a complicated semiconductor process. Herein, a NO2 sensor was fabricated by doping PbS QDs with poly(3-hexylthiophene) (P3HT). The as-developed sensor exhibited high responsivity to 100-0.4-ppm NO2 gas with a resolution of 200 ppb owing to the stability of the thin film and high hole mobility of P3HT. | Kwon, Jinbeom; Ha, Yuntae; Choi, Suji; Jung, Dong Geon; An, Hee kyung; Kong, Seong Ho; Jung, Daewoong | Korea Inst Ind Technol KITECH, Adv Mobil Syst Grp, Daegu 42994, South Korea; Kyungpook Natl Univ, Sch Elect & Elect Engn, Daegu 41566, South Korea | Ha, Yuntae/MXL-2699-2025 | 57191591392; 58018481200; 58017819200; 56675241000; 56647468900; 57204537951; 36019307900 | shkong@knu.ac.kr;dwjung@kitech.re.kr; | SCIENTIFIC REPORTS | SCI REP-UK | 2045-2322 | 14 | 1 | SCIE | MULTIDISCIPLINARY SCIENCES | 2024 | 3.9 | 18.1 | 2.04 | 2025-05-07 | 8 | 8 | Gas sensor; NO2; PbS QDs; P3HT | SENSING CHARACTERISTICS; SOLAR-CELLS; THIN-FILMS; EFFICIENCY; HETEROJUNCTION; ZNO | Gas sensor; NO<sub>2</sub>; P3HT; PbS QDs | metal oxide; nitrogen dioxide; quantum dot; article; car; controlled study; drug analysis; drug therapy; gas; greenhouse gas; greenhouse gas emission; heating; high temperature; room temperature; semiconductor; sensor | English | 2024 | 2024-09-04 | 10.1038/s41598-024-71453-9 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Statistical analysis of the association between El Niño and the biological carbon pump in the East Sea (Japan Sea) | Understanding the impacts of climate change on oceanic carbon cycling is important from a carbon sequestration perspective. A sediment trap study focused on the biological carbon pump system in the Ulleung Basin (UB) in the southwestern part of the East Sea (Japan Sea) was conducted from 2011 to 2017. Particulate organic carbon (POC) flux significantly increased by 37, 56, and 43% from 2014 to 2016 during the El Ni & ntilde;o phase. We examined data related to water current variability, such as sea surface height, current velocity, and eddy frequency to understand their roles in particle transport. In addition, a Martin curve was employed to analyze the rate of vertical attenuation of POC flux in the UB. Current variability could be the most important factor influencing the increase in sinking-particle flux during the El Ni & ntilde;o phase. | Jang, Geunsoo; Hong, Seunghyun; Oh, Janghun; Kim, Young-Il; Kim, Minkyoung; Lee, Hyojung | Kyungpook Natl Univ, Nonlinear Dynam & Math Applicat Ctr, Daegu 41566, South Korea; Kyungpook Natl Univ, Dept Stat, Daegu 41566, South Korea; Korea Inst Ocean Sci & Technol, East Sea Res Inst, Uljin 36315, South Korea; Kyungpook Natl Univ, KNU Inst Basic Sci, Dept Oceanog, KNU G LAMP Project Grp, Daegu 41566, South Korea | 57471384400; 59401931400; 59251295500; 57214047119; 57212315624; 57196021198 | minkyoung@knu.ac.kr;hjlee@knu.ac.kr; | SCIENTIFIC REPORTS | SCI REP-UK | 2045-2322 | 14 | 1 | SCIE | MULTIDISCIPLINARY SCIENCES | 2024 | 3.9 | 18.1 | 0 | 2025-05-07 | 0 | 0 | Particulate organic carbon; Biological carbon pump; Statistic analysis; Eddy; Lateral transport | ULLEUNG BASIN; PACIFIC-OCEAN; HOT-SPOT; CHLOROPHYLL; ENSO; PARTICLES; FLUXES; EXPORT; DEPTH; NINO | Biological carbon pump; Eddy; Lateral transport; Particulate organic carbon; Statistic analysis | organic carbon; article; carbon cycling; carbon pump; carbon sequestration; climate change; Japan; pharmaceutics; pump; sea; sediment; statistical analysis; velocity | English | 2024 | 2024-11-04 | 10.1038/s41598-024-74818-2 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Strategy to improve synaptic behavior of ion-actuated synaptic transistors-the use of ion blocking layer to improve state retention | Synaptic transistors (STs) with a gate/electrolyte/channel stack, where mobile ions are electrically driven across the solid electrolyte, have been considered as analog weight elements for neuromorphic computing. The current (ID) between the source and drain in the ST is analogously updated by gate voltage (VG) pulses, enabling high pattern recognition accuracy in neuromorphic systems; however, the governing physical mechanisms of the ST are not fully understood yet. Our previous physics-based simulation study showed that ion movement in the electrolyte, rather than the electrochemical reactions that occur in the channel, plays an important role in switching. In this study, we experimentally explore the properties of the HfOx electrolyte and show that by tuning the density of oxygen vacancies, it can assume the dual role of electrolyte and channel. We demonstrate analog synaptic behavior using a novel ST with a two-layer stack of CuOx/HfOx, where the CuOx is the gate and Cu ion reservoir, and the HfOx is the electrolyte and channel. To improve state retention and linearity, we introduce a Cu ion transport barrier in the form of a dense and stoichiometric Al2O3 layer. The CuOx/Al2O3/HfOx exhibits excellent state retention and improved potentiation and depression response. Energy dispersive spectroscopy mapping following potentiation confirms the role of the Al2O3 layer in confining the Cu ions in the HfOx layer. We also show that a two-step programming scheme can further enhance synaptic response and demonstrate high recognition accuracy on the Fashion-MNIST dataset in simulation. | Jeon, Seonuk; Tessler, Nir; Kim, Nayeon; Hong, Eunryeong; Kim, Hyun Wook; Woo, Jiyong | Kyungpook Natl Univ, Sch Elect & Elect Engn, Daegu 41566, South Korea; Technion Israel Inst Technol, Sara & Moshe Zisapel Nanoelect Ctr, Elect & Comp Engn Dept, IL-3200003 Haifa, Israel; Columbia Univ, Dept Earth & Environm Engn, New York, NY 10027 USA | Tessler, Nir/A-9849-2008 | 57955098300; 7007034316; 59884547500; 57556070800; 57557016000; 53985749100 | jiyong.woo@knu.ac.kr; | SCIENTIFIC REPORTS | SCI REP-UK | 2045-2322 | 14 | 1 | SCIE | MULTIDISCIPLINARY SCIENCES | 2024 | 3.9 | 18.1 | 0.82 | 2025-05-07 | 4 | 3 | copper ion; electrolyte; ion; oxygen; article; controlled study; depression; electric potential; electrochemical analysis; energy dispersive X ray spectroscopy; ion current; ion transport; pattern recognition; simulation; transistor | English | 2024 | 2024-02-29 | 10.1038/s41598-024-55681-7 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||||
| ○ | ○ | Article | TASL mediates keratinocyte differentiation by regulating intracellular calcium levels and lysosomal function | Maintaining epidermal homeostasis relies on a tightly organized process of proliferation and differentiation of keratinocytes. While past studies have primarily focused on calcium regulation in keratinocyte differentiation, recent research has shed light on the crucial role of lysosome dysfunction in this process. TLR adaptor interacting with SLC15A4 on the lysosome (TASL) plays a role in regulating pH within the endo-lysosome. However, the specific role of TASL in keratinocyte differentiation and its potential impact on proliferation remains elusive. In our study, we discovered that TASL deficiency hinders the proliferation and migration of keratinocytes by inducing G1/S cell cycle arrest. Also, TASL deficiency disrupts proper differentiation process in TASL knockout human keratinocyte cell line (HaCaT) by affecting lysosomal function. Additionally, our research into calcium-induced differentiation showed that TASL deficiency affects calcium modulation, which is essential for keratinocyte regulation. These findings unveil a novel role of TASL in the proliferation and differentiation of keratinocytes, providing new insights into the intricate regulatory mechanisms of keratinocyte biology. | Park, Ji Yeong; Kim, Hyeng-Soo; Hyung, Hyejin; Jang, Soyeon; Ko, Jiwon; Lee, Jin Hong; Kim, Si-Yong; Park, Song; Yi, Junkoo; Park, Sijun; Lim, Su-Geun; Kim, Seonggon; Lee, Sanggyu; Kim, Myoung Ok; Jang, Soyoung; Ryoo, Zae Young | Kyungpook Natl Univ, Sch Life Sci, BK21 FOUR KNU Creat BioRes Grp, Daegu 41566, South Korea; Kyungpook Natl Univ, Inst Life Sci & Biotechnol, Daegu 41566, South Korea; Gyeongsang Natl Univ, Div Anim Sci, Jinju 52828, South Korea; Gyeongsang Natl Univ, Inst Agr & Life Sci IALS, Jinju 52828, South Korea; Hankyong Natl Univ, Sch Anim Life Convergence Sci, Anseong 17579, South Korea; Daegu Gyeongbuk Med Innovat Fdn, Preclin Res Ctr, Daegu, South Korea; Kyungpook Natl Univ, Res Inst Innovat Anim Sci, Dept Anim Sci & Biotechnol, Sangju Si 37224, Gyeongsangbuk D, South Korea | RYOO, ZAEYOUNG/AAQ-1573-2020; Yi, Junkoo/JBR-8507-2023; Lee, Jeong/C-8864-2011 | 57247511800; 35112301400; 57247294000; 57226661947; 57226659428; 57247726000; 57212197751; 57139047900; 56182537200; 54682212300; 56044587400; 55718780800; 7601418915; 8934745900; 57139360300; 16937104900 | grayciel@knu.ac.kr;wkdthdud21@naver.com;jaewoong64@knu.ac.kr; | SCIENTIFIC REPORTS | SCI REP-UK | 2045-2322 | 14 | 1 | SCIE | MULTIDISCIPLINARY SCIENCES | 2024 | 3.9 | 18.1 | 0 | 2025-05-07 | 1 | 1 | SKIN; PROLIFERATION | Calcium; Cell Differentiation; Cell Line; Cell Movement; Cell Proliferation; Humans; Keratinocytes; Lysosomes; calcium; cell differentiation; cell line; cell motion; cell proliferation; cytology; human; keratinocyte; lysosome; metabolism | English | 2024 | 2024-05-14 | 10.1038/s41598-024-61674-3 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Temporal trends and long-term outcomes of radiofrequency ablation for hepatocellular carcinoma within the Milan criteria | No study has analysed the temporal trends of the long-term results and clinical characteristics of patients with hepatocellular carcinoma (HCC) treated using radiofrequency ablation (RFA). Therefore, we examined temporal trends of characteristics of patients and treatment-na & iuml;ve HCCs within the Milan criteria treated by RFA over 20 years. We retrospectively analysed 1099 patients with HCC within the Milan criteria treated with percutaneous RFA from January 2000 to December 2019. The overall survival (OS), recurrence-free survival (RFS), and factors affecting survival and local tumor progression were analysed using the Kaplan-Meier method and Cox proportional hazards model. A trend test was performed to analyse the changing trends in participants and treatment outcomes. The overall and RFS of patients improved during the later period. In addition, viral hepatitis-related HCC incidence decreased, whereas that of alcohol- or non-alcoholic fatty liver disease-related HCC increased from the earlier to the later period (P for trend < 0.001). HBV antiviral therapy was increased and improved OS and RFS in patients treated using RFA. The outcomes after RFA over a 20-year period improved due to changes over time in target tumors and patients. The results could be useful for selecting patients who will benefit from RFA. | Jang, Se Young; Park, Soo Young; Kweon, Young Oh; Lee, Yu Rim; Ryeom, Hun Kyu; Cha, Jung Guen; Kim, Sungmin; Lee, Won Kee; Jo, Ae Jeong; Tak, Won Young | Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Internal Med, 130 Dongdeok Ro, Daegu 41944, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Radiol, Daegu, South Korea; Univ Ulsan, Dept Biomed Engn, Ulsan, South Korea; Kyungpook Natl Univ, Sch Med, Dept Med Informat, Daegu, South Korea; Andong Natl Univ, Dept Informat Stat, Andong, South Korea | 57202881977; 57191674344; 7004694832; 57194094753; 6505864513; 57206855971; 57835343800; 22953484700; 57190185428; 7004074582 | wytak@knu.ac.kr;eworldcup@gmail.com; | SCIENTIFIC REPORTS | SCI REP-UK | 2045-2322 | 14 | 1 | SCIE | MULTIDISCIPLINARY SCIENCES | 2024 | 3.9 | 18.1 | 0 | 2025-05-07 | 0 | 0 | THERMOSENSITIVE LIPOSOMAL DOXORUBICIN; 1ST-LINE TREATMENT; PROGNOSTIC-FACTORS; THERAPY; ANALOGS | Adult; Aged; Carcinoma, Hepatocellular; Female; Humans; Kaplan-Meier Estimate; Liver Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Radiofrequency Ablation; Retrospective Studies; Treatment Outcome; adult; aged; epidemiology; female; human; Kaplan Meier method; liver cell carcinoma; liver tumor; male; middle aged; mortality; pathology; radiofrequency ablation; retrospective study; surgery; treatment outcome; tumor recurrence | English | 2024 | 2024-08-27 | 10.1038/s41598-024-70494-4 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||||
| ○ | ○ | Article | The complete plastome sequences of invasive weed Parthenium hysterophorus: genome organization, evolutionary significance, structural features, and comparative analysis | Parthenium hysterophorus, a globally widespread weed, poses a significant threat to agricultural ecosystems due to its invasive nature. We investigated the chloroplast genome of P. hysterophorus in this study. Our analysis revealed that the chloroplast genome of P. hysterophorus spans a length of 151,881 base pairs (bp). It exhibits typical quadripartite structure commonly found in chloroplast genomes, including inverted repeat regions (IR) of 25,085 bp, a small single copy (SSC) region of 18,052 bp, and a large single copy (LSC) region of 83,588 bp. A total of 129 unique genes were identified in P. hysterophorus chloroplast genomes, including 85 protein-coding genes, 36 tRNAs, and eight rRNAs genes. Comparative analysis of the P. hysterophorus plastome with those of related species from the tribe Heliantheae revealed both conserved structures and intriguing variations. While many structural elements were shared among the species, we identified a rearrangement in the large single-copy region of P. hysterophorus. Moreover, our study highlighted notable gene divergence in several specific genes, namely matK, ndhF, clpP, rps16, ndhA, rps3, and ndhD. Phylogenetic analysis based on the 72 shared genes placed P. hysterophorus in a distinct clade alongside another species, P. argentatum. Additionally, the estimated divergence time between the Parthenium genus and Helianthus (sunflowers) was approximately 15.1 million years ago (Mya). These findings provide valuable insights into the evolutionary history and genetic relationships of P. hysterophorus, shedding light on its divergence and adaptation over time. | Asaf, Sajjad; Jan, Rahmatullah; Asif, Saleem; Bilal, Saqib; Khan, Abdul Latif; Al-Rawahi, Ahmed N.; Kim, Kyung-Min; AL-Harrasi, Ahmed | Univ Nizwa, Nat & Med Sci Res Ctr, Nizwa 616, Oman; Kyungpook Natl Univ, Dept Appl Biosci, Daegu 41566, South Korea; Univ Houston, Dept Engn Technol, Sugar Land, TX 77479 USA | ; Khan, Abdul/H-5910-2011; Asaf, Sajjad/ABA-3647-2021; Ul-Hamid, Anwar/B-7297-2015; Jan, Rahmatullah/AIC-3439-2022 | 57200621537; 56595059900; 57201981969; 57396413700; 57031617400; 26639372800; 7801308442; 34868260300; 6506093146 | sajadasif2000@gmail.com;saqib@unizwa.edu.om;aharrasi@unizwa.edu.om; | SCIENTIFIC REPORTS | SCI REP-UK | 2045-2322 | 14 | 1 | SCIE | MULTIDISCIPLINARY SCIENCES | 2024 | 3.9 | 18.1 | 0.41 | 2025-05-07 | 1 | 1 | Weed; Chloroplast; Divergence; Phylogenetic; Synteny | CHLOROPLAST DNA INVERSION; PHYLOGENETIC-RELATIONSHIPS; MANAGEMENT; SOFTWARE; GENE; EXPRESSION; SORGHUM; TOOLS; ACCD | Chloroplast; Divergence; Phylogenetic; Synteny; Weed | Asteraceae; Ecosystem; Genome, Chloroplast; Parthenium hysterophorus; Phylogeny; Plant Weeds; ribosome RNA; transfer RNA; article; chloroplast; chloroplast genome; cladistics; controlled study; female; genetic variability; genome analysis; inverted repeat; molecular phylogeny; nonhuman; Parthenium; Parthenium hysterophorus; phylogeny; sunflower; synteny; weed | English | 2024 | 2024-02-18 | 10.1038/s41598-024-54503-0 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Correction | The complete plastome sequences of invasive weed Parthenium hysterophorus: genome organization, evolutionary significance, structural features, and comparative analysis (vol 14, 4006, 2024) | Lubna; Asaf, Sajjad; Jan, Rahmatullah; Asif, Saleem; Bilal, Saqib; Khan, Abdul Latif; Al-Rawahi, Ahmed N.; Kim, Kyung-Min; AL-Harrasi, Ahmed | Univ Nizwa, Nat & Med Sci Res Ctr, Nizwa 616, Oman; Kyungpook Natl Univ, Dept Appl Biosci, Daegu 41566, South Korea; Univ Houston, Dept Engn Technol, Sugar Land, TX 77479 USA | Ul-Hamid, Anwar/B-7297-2015; Asaf, Sajjad/ABA-3647-2021; Jan, Rahmatullah/AIC-3439-2022; Khan, Abdul/H-5910-2011 | 57200621537; 56595059900; 57201981969; 57396413700; 57031617400; 26639372800; 7801308442; 34868260300; 6506093146 | sajadasif2000@gmail.com;saqib@unizwa.edu.om;aharrasi@unizwa.edu.om; | SCIENTIFIC REPORTS | SCI REP-UK | 2045-2322 | 14 | 1 | SCIE | MULTIDISCIPLINARY SCIENCES | 2024 | 3.9 | 18.1 | 0 | 2025-05-07 | 0 | 0 | NEUROLOGICAL MANIFESTATIONS; SARS-COV-2 INFECTION; CHILDREN; COVID-19; METAANALYSIS; SPECTRUM | article; chloroplast; diagnosis; genome analysis; geological time; nonhuman; Parthenium hysterophorus; phylogenetic tree; species differentiation; synteny; weed; erratum; human | English | 2024 | 2024-02-27 | 10.1038/s41598-024-55391-0 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||||
| ○ | ○ | Article | The effect of dialysis modality on annual mortality: A prospective cohort study | Despite numerous studies on the effect of each dialysis modality on mortality, the issue remains controversial. We investigated the hazard rate of mortality in patients with incident end-stage renal disease (ESRD) concerning initial dialysis modality (hemodialysis vs. peritoneal dialysis). Using a nationwide, multicenter, prospective cohort in South Korea, we studied 2207 patients, of which 1647 (74.6%) underwent hemodialysis. We employed the weighted Fine and Gray model over the follow-up period using inverse probability of treatment and censoring weighting. Landmark analysis was used for identifying the changing effect of dialysis modality on individuals who remained event-free at each landmark point. No significant difference in hazard rate was observed overall. However, the peritoneal dialysis group had a significantly higher hazard rate than the hemodialysis group among patients under 65 years after 4- and 5- year follow-up. A similar pattern was observed among those with diabetes mellitus. Landmark analysis also showed the higher hazard rate for peritoneal dialysis at 2 years for the education-others group and at 3 years for the married group. These findings may inform dialysis modality decisions, suggesting a preference for hemodialysis in young patients with diabetes, especially for follow-ups longer than 3 years. | Kim, Yae Hyun; Kim, Yeonjin; Ha, Nayoung; Cho, Jang-Hee; Kim, Yon Su; Kang, Shin-Wook; Kim, Nam-Ho; Yang, Chul Woo; Kim, Yong-Lim; Lee, Jung Pyo; Lee, Woojoo; Oh, Hyung Jung | Seoul Natl Univ Hosp, Dept Internal Med, Seoul, South Korea; Seoul Natl Univ, Grad Sch Publ Hlth, Dept Publ Hlth Sci, Seoul, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Internal Med, Daegu, South Korea; Seoul Natl Univ, Dept Internal Med, Coll Med, Seoul, South Korea; Yonsei Univ, Dept Internal Med, Coll Med, Seoul, South Korea; Chonnam Natl Univ, Dept Internal Med, Med Sch, Gwangju, South Korea; Catholic Univ Korea, Seoul St Marys Hosp, Dept Internal Med, Coll Med, Seoul, South Korea; Seoul Natl Univ, Dept Internal Med, Boramae Med Ctr, Seoul, South Korea; Sheikh Khalifa Specialty Hosp, Dept Nephrol, Ras Al Khaymah, U Arab Emirates | Ha, NaYoung/IAP-4132-2023; KIM, YOUNG JIN/E-9374-2011; Cho, Jang-hee/ABD-3534-2020; Kim, Yon/J-2743-2012; Kim, Yong-Lim/AGK-3172-2022; Kim, Sejoong/J-5356-2015 | 58689717000; 57816137000; 58770915000; 7403536291; 7410205767; 34768359700; 56605215700; 7407743404; 55633533600; 56028990400; 36170681600; 8931430000 | lwj221@gmail.com;ohjmd0121@gmail.com; | SCIENTIFIC REPORTS | SCI REP-UK | 2045-2322 | 14 | 1 | SCIE | MULTIDISCIPLINARY SCIENCES | 2024 | 3.9 | 18.1 | 0 | 2025-05-07 | 0 | 0 | Hemodialysis; Peritoneal dialysis; Mortality; End-stage renal disease | PERITONEAL-DIALYSIS; HEMODIALYSIS; SURVIVAL; SELECTION; OUTCOMES; DISEASE | End-stage renal disease; Hemodialysis; Mortality; Peritoneal dialysis | Adult; Aged; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Peritoneal Dialysis; Prospective Studies; Renal Dialysis; Republic of Korea; adult; aged; chronic kidney failure; clinical trial; epidemiology; female; hemodialysis; human; male; middle aged; mortality; multicenter study; peritoneal dialysis; procedures; prospective study; South Korea; therapy | English | 2024 | 2024-06-18 | 10.1038/s41598-024-64914-8 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | The impact of shortening patient-doctor contact duration on early peritoneal dialysis-related infections | Early peritoneal dialysis (PD)-related infection is a severe complication. This study investigated the relationship between patient-doctor contact (PDC) duration and early PD-related infection. In the Peritoneal Dialysis Outcomes and Practice Patterns Study (PDOPPS) Korea, incident dialysis patients receiving PD were divided into two groups based on PDC duration (= 15 min), which was defined as the duration a nephrologist typically spends with a patient receiving PD during each visit according to the facility practice pattern. Early risks of PD-related infections, such as peritonitis and catheter-related infection (onset within 3 and 12 months of PD), were compared to the PDC duration using Cox regression. The study included 276 patients (184 [66.7%] in the shorter PDC group [= 15 min]). The average age did not differ between the groups. The incidences of 3- and 12-month PD-related infections were significantly lower in the longer PDC group than in the shorter PDC group (3 months: 1.1% versus 9.8%, P = 0.007; 12 months: 9.8% versus 23.4%, P = 0.007). Longer PDC was independently associated with a lower risk of PD-related infections at 3 and 12 months (3 months: adjusted hazard ratio [aHR], 0.11; 95% confidence interval [CI], 0.02-0.85, P = 0.034; 12 months: aHR, 0.43; 95% CI 0.19-0.99, P = 0.048). Overall, a longer PDC duration was associated with a significantly lower risk of early PD-related infection. | Lim, Jeong-Hoon; Seo, Yu Jin; Pecoits-Filho, Roberto; Bieber, Brian; Perl, Jeffrey; Johnson, David W.; Jung, Hee-Yeon; Choi, Ji-Young; Cho, Jang-Hee; Kim, Chan-Duck; Oh, Kook-Hwan; Park, Sun-Hee; Kim, Yong-Lim | Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu, South Korea; Kyungpook Natl Univ, Dept Stat, Daegu, South Korea; Arbor Res Collaborat Hlth, Ann Arbor, MI USA; Univ Toronto, St Michaels Hosp, Unity Hlth, Div Nephrol,Dept Med, Toronto, ON, Canada; Univ Queensland, Australasian Kidney Trials Network, Brisbane, Qld, Australia; Princess Alexandra Hosp, Dept Kidney & Transplant Serv, Brisbane, Australia; Seoul Natl Univ Hosp, Dept Internal Med, Seoul, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Div Nephrol,Dept Internal Med, 130 Dongdeok Ro, Daegu 41944, South Korea | Kim, Yong-Lim/AGK-3172-2022; Park, Sun-Hee/LMN-0033-2024; Oh, Kook-Hwan/MDS-5373-2025; Jung, Hee-Yeon/AFB-8578-2022; Perl, Jeffrey/HKW-4066-2023; Lim, Jeong-Hoon/ABE-6003-2020; Han, Seung Hyeok/K-4559-2018; Cho, Jang-hee/ABD-3534-2020 | 55360244300; 59167627900; 7004549287; 53982698300; 57192120457; 34975083900; 57196396467; 7501393222; 7403536291; 8558530700; 7402728369; 7501831741; 55633533600; 13307391500; 56123401500; 33067497300; 56508055400; 8310761400; 57190402513; 35100416100; 57203206532; 36523820900; 56605215700; 7404787457; 14621981000; 57092930500; 56873349600; 18233343300; 34880445500; 36162581500; 59782224200; 55285801300; 55716130600 | sh-park@knu.ac.kr;ylkim@knu.ac.kr; | SCIENTIFIC REPORTS | SCI REP-UK | 2045-2322 | 14 | 1 | SCIE | MULTIDISCIPLINARY SCIENCES | 2024 | 3.9 | 18.1 | 0.41 | 2025-05-07 | 1 | 1 | Catheter-related infection; Patient-doctor contact hour; PD-related infection; Peritoneal dialysis; Peritonitis | PHYSICIAN CONTACT; RISK; FREQUENCY; MORTALITY; OUTCOMES; PREVENTION; DISEASE; UPDATE; SYSTEM; CARE | Catheter-related infection; Patient–doctor contact hour; PD-related infection; Peritoneal dialysis; Peritonitis | Adult; Aged; Catheter-Related Infections; Female; Humans; Incidence; Male; Middle Aged; Peritoneal Dialysis; Peritonitis; Physician-Patient Relations; Proportional Hazards Models; Republic of Korea; Risk Factors; Time Factors; adult; adverse event; aged; catheter infection; doctor patient relationship; epidemiology; etiology; female; human; incidence; male; middle aged; peritoneal dialysis; peritonitis; proportional hazards model; risk factor; South Korea; time factor | English | 2024 | 2024-10-03 | 10.1038/s41598-024-74205-x | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | The limited role of serum neurofilament light chain in predicting pain severity of patients with diabetic polyneuropathy | Pain is one of many complaints expressed by patients with diabetic polyneuropathy. However, no objective measure for pain severity has been available. Neurofilament light chains have been widely used for assessing axonal damage in the neuronal system. Hence, we sought to investigate whether neurofilament light chains can serve as a marker reflecting pain severity in diabetic polyneuropathy. We enrolled the patients with diabetic polyneuropathy. Serum concentrations of neurofilament light chain were then measured using a single-molecule array. Pain severity was evaluated using painDETECT and the Brief Pain Inventory. Moreover, laboratory results including, serum creatinine, HbA1c, and glomerular filtration rate. A correlation test was used to analyze each variable. A total of 42 patients were enrolled. Neurofilament light chain levels were unable to reflect current neuropathic pain severity. However, high levels of neurofilament light chain were a significant predictor of poor diabetes control (r = 0.41; p = 0.02) and kidney damage (r = 0.45; p = 0.01). Serum levels of neurofilament light chain could not reflect current pain severity but was strongly associated with kidney dysfunction and poor diabetes control. Other biomarkers that could predict pain severity need to be uncovered. | Kim, A-Sol; Lee, Jong-Mok | Kyungpook Natl Univ, Kyungpook Natl Univ Chilgok Hosp, Sch Med, Dept Family Med, Daegu, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Radiol, 680 Gukchaebosang Ro, Daegu 41944, South Korea | Lee, Jong-Mok/KVY-9550-2024 | 57203290656; 57192075673 | azulmar@gmail.com; | SCIENTIFIC REPORTS | SCI REP-UK | 2045-2322 | 14 | 1 | SCIE | MULTIDISCIPLINARY SCIENCES | 2024 | 3.9 | 18.1 | 0.82 | 2025-05-07 | 3 | 2 | Diabetes mellitus; Axons; Peripheral nerve injuries | NEUROPATHIC PAIN; KOREAN VERSION; QUESTIONNAIRE; PAINDETECT; LIFE | Axons; Diabetes mellitus; Peripheral nerve injuries | Aged; Biomarkers; Diabetic Neuropathies; Female; Humans; Male; Middle Aged; Neuralgia; Neurofilament Proteins; Pain Measurement; Severity of Illness Index; biological marker; neurofilament protein; neurofilament protein L; aged; blood; diabetic neuropathy; diagnosis; female; human; male; middle aged; neuralgia; pain measurement; procedures; severity of illness index | English | 2024 | 2024-07-06 | 10.1038/s41598-024-66444-9 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Correction | The prediction of sagittal chin point relapse following two-jaw surgery using machine learning (vol 13, 17005, 2023) | Kim, Young Ho; Kim, Inhwan; Kim, Yoon-Ji; Kim, Minji; Cho, Jin-Hyoung; Hong, Mihee; Kang, Kyung-Hwa; Lim, Sung-Hoon; Kim, Su-Jung; Kim, Namkug; Shin, Jeong Won; Sung, Sang-Jin; Baek, Seung-Hak; Chae, Hwa Sung | Ajou Univ, Inst Oral Hlth Sci, Dept Orthodont, Sch Med, Suwon, South Korea; Univ Ulsan, Asan Med Inst Convergence Sci & Technol, Dept Convergence Med, Asan Med Ctr,Coll Med, Seoul, South Korea; Univ Ulsan, Dept Orthodont, Asan Med Ctr, Coll Med, Seoul, South Korea; Ewha Womans Univ, Dept Orthodont, Coll Med, Seoul, South Korea; Chonnam Natl Univ, Dept Orthodont, Sch Dent, Gwangju, South Korea; Kyungpook Natl Univ, Sch Dent, Dept Orthodont, Daegu, South Korea; Wonkwang Univ, Sch Dent, Dept Orthodont, Iksan, South Korea; Chosun Univ, Dept Orthodont, Coll Dent, Gwangju, South Korea; Kyung Hee Univ, Dept Orthodont, Sch Dent, Seoul, South Korea; Seoul Natl Univ, Sch Dent, Dept Orthodont, Dent Res Inst, Seoul, South Korea; Chung Ang Univ, Dept Orthodont, Gwangmyeong Hosp, Gwangmyeong, South Korea | ; Kim, Namkug/E-3843-2012; Kim, Yoon-Ji/ABG-7898-2021; Sung, Sang Jin/KBQ-4217-2024; Baek, Seung-Hak/NOE-8444-2025 | 57207443980; 57222816092; 57221435554; 57201330607; 15764519700; 57190379016; 35285868600; 36793499100; 57039799500; 16550058300; 57210164233; 7202731963; 35090967400; 57203779388 | hwasungchae@cauhs.or.kr; | SCIENTIFIC REPORTS | SCI REP-UK | 2045-2322 | 14 | 1 | SCIE | MULTIDISCIPLINARY SCIENCES | 2024 | 3.9 | 18.1 | 0 | 2025-05-07 | 0 | 0 | article; drug therapy; human; machine learning; orthognathic surgery; prediction; prevention; relapse; spelling; surgery; clinical article; diagnosis; erratum; female | English | 2024 | 2024-02-02 | 10.1038/s41598-024-53035-x | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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