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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Article | Characterization and structural analysis of the endo-1,4-β-xylanase GH11 from the hemicellulose-degrading Thermoanaerobacterium saccharolyticum useful for lignocellulose saccharification | Xylanases are important for the enzymatic breakdown of lignocellulose-based biomass to produce biofuels and other value-added products. We report functional and structural analyses of TsaGH11, an endo-1,4-beta-xylanase from the hemicellulose-degrading bacterium, Thermoanaerobacterium saccharolyticum. TsaGH11 was shown to be a thermophilic enzyme that favors acidic conditions with maximum activity at pH 5.0 and 70 degrees C. It decomposes xylans from beechwood and oat spelts to xylose-containing oligosaccharides with specific activities of 5622.0 and 3959.3 U mg(-1), respectively. The kinetic parameters, K-m and k(cat) towards beechwood xylan, are 12.9 mg mL(-1) and 34,015.3 s(-1), respectively, resulting in k(cat)/K-m value of 2658.7 mL mg(-1) s(-1), higher by 10(2)-10(3) orders of magnitude compared to other reported GH11s investigated with the same substrate, demonstrating its superior catalytic performance. Crystal structures of TsaGH11 revealed a beta-jelly roll fold, exhibiting open and close conformations of the substrate-binding site by distinct conformational flexibility to the thumb region of TsaGH11. In the room-temperature structure of TsaGH11 determined by serial synchrotron crystallography, the electron density map of the thumb domain of the TsaGH11 molecule, which does not affect crystal packing, is disordered, indicating that the thumb domain of TsaGH11 has high structural flexibility at room temperature, with the water molecules in the substrate-binding cleft being more disordered than those in the cryogenic structure. These results expand our knowledge of GH11 structural flexibility at room temperature and pave the way for its application in industrial biomass degradation. | Kim, In Jung; Kim, Soo Rin; Kim, Kyoung Heon; Bornscheuer, Uwe T.; Nam, Ki Hyun | Gyeongsang Natl Univ, Inst Agr & Life Sci, Dept Food Sci & Technol, Jinju 52828, South Korea; Univ Greifswald, Inst Biochem, Dept Biotechnol & Enzyme Catalysis, Felix Hausdorff Str 4, D-17489 Greifswald, Germany; Kyungpook Natl Univ, Sch Food Sci & Biotechnol, Daegu 41566, South Korea; Korea Univ, Grad Sch, Dept Biotechnol, Seoul 02841, South Korea; Kookmin Univ, Coll Gen Educ, Seoul 02707, South Korea | Nam, Ki Hyun/N-6812-2019; Bornscheuer, Uwe/C-4612-2012; Kim, Soo Rin/X-2192-2019 | 57195531808; 36659584200; 34770896300; 7006947469; 13808340200 | structure@kookmin.ac.kr; | SCIENTIFIC REPORTS | SCI REP-UK | 2045-2322 | 13 | 1 | SCIE | MULTIDISCIPLINARY SCIENCES | 2023 | 3.8 | 18.3 | 2.95 | 2025-06-25 | 25 | 25 | XYLANASE; BIOMASS; PURIFICATION | Endo-1,4-beta Xylanases; Hydrolysis; Polysaccharides; Substrate Specificity; Thermoanaerobacterium saccharolyticum; Xylans; endo 1,4 beta xylanase; hemicellulose; lignocellulose; polysaccharide; xylan; chemistry; enzyme specificity; hydrolysis; metabolism | English | 2023 | 2023-10-13 | 10.1038/s41598-023-44495-8 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Comparing zero-profile and conventional cage and plate in anterior cervical discectomy and fusion using finite-element modeling | Conventional cage and plate (CCP) implants usually used in ACDF surgery, do have limitations such as the development of postoperative dysphagia, adjacent segment degeneration, and soft tissue injury. To reduce the risk of these complications, zero-profile stand-alone cage were developed. We used finite-element modeling to compare the total von Mises stress applied to the bone, disc, endplate, cage and screw when using CCP and ZPSC implants. A 3-dimensional FE (Finite element) analysis was performed to investigate the effects of the CCP implant and ZPSC on the C3 similar to T1 vertebrae. We confirmed that the maximum von Mises stress applied with ZPSC implants was more than 2 times greater in the endplate than that applied with CCP implants. The 3D analysis of the ZPSC model von Mises stress measurements of screw shows areas of higher stress in red. Although using ZPSC implants in ACDF reduces CCP implant-related sequalae such as dysphagia, we have shown that greater von Mises stress is applied to the endplate, and screw when using ZPSC implants. This may explain the higher subsidence rate associated with ZPSC implant use in ACDF. When selecting an implant in ACDF, surgeons should consider patient characteristics and the advantages and disadvantages of each implant type. | Ahn, Chang-Hwan; Kang, Sungwook; Cho, Mingoo; Kim, Seong-Hun; Kim, Chi Heon; Han, Inbo; Kim, Chul-Hyun; Noh, Sung Hyun; Kim, Kyoung-Tae; Hwang, Jong-Moon | Kyungpook Natl Univ Hosp, Dept Rehabil Med, Daegu 41944, South Korea; Korea Inst Ind Technol, Precis Mech Proc & Control R Grp, Jinju Si 52845, Gyeongsangnam D, South Korea; Seoul Natl Univ, Dept Neurosurg, Coll Med, Seoul, South Korea; CHA Univ, Sch Med, Dept Neurosurg, CHA Bundang Med Ctr, Seongnam, South Korea; Ajou Univ, Dept Neurosurg, Coll Med, Suwon, South Korea; Kyungpook Natl Univ Hosp, Dept Neurosurg, Daegu 41944, South Korea; Kyungpook Natl Univ, Sch Med, Dept Neurosurg, Daegu 41944, South Korea; Kyungpook Natl Univ, Sch Med, Dept Rehabil Med, Daegu 41944, South Korea | Kim, Chi/J-6536-2019; KANG, SUNGWOOK/AAF-6339-2021 | 58076572400; 55611458600; 57556834700; 57848557900; 35145892000; 9338449900; 59603554500; 57194978247; 57201369790; 56367634000 | nskimkt7@gmail.com;hti82@hanmail.net; | SCIENTIFIC REPORTS | SCI REP-UK | 2045-2322 | 13 | 1 | SCIE | MULTIDISCIPLINARY SCIENCES | 2023 | 3.8 | 18.3 | 0.94 | 2025-06-25 | 8 | 8 | ANCHORED SPACER; SUBSIDENCE; DYSPHAGIA; FIXATION; LEVEL; SPINE; SPONDYLOSIS; OUTCOMES; DEVICE; ACDF | Bone Plates; Bone Screws; Deglutition Disorders; Diskectomy; Humans; Surgeons; discectomy; dysphagia; human; surgeon | English | 2023 | 2023-09-22 | 10.1038/s41598-023-43086-x | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Comparison between three types of needles for endoscopic ultrasound-guided tissue acquisition of pancreatic solid masses: a multicenter observational study | It is debatable which needle has clear superiority of diagnostic performance in endoscopic ultrasound (EUS)-guided fine needle biopsy (FNB) of solid pancreatic masses. This study aimed to compare the performance of three needles and determine the variables that affect diagnostic accuracy. From March 2014 to May 2020, 746 patients with solid pancreatic masses who underwent EUS-FNB using three types of needles (Franseen needle, Menghini-tip needle, and Reverse-bevel needle) were retrospectively reviewed. Multivariate analysis using a logistic regression model was used to identify factors related to diagnostic accuracy. There were significant differences between the groups regarding the procurement rate of the histologic and optimal quality cores (Franseen vs. Menghini-tip vs. Reverse-bevel: 98.0% [192/196] vs. 85.8% [97/113] vs. 91.9% [331/360], P = 2 cm (odds ratio [OR] 5.36, 95% confidence interval [CI] 3.40-8.47, P < 0.001) and fanning technique (OR 1.70, 95% CI 1.00-2.86, P = 0.047) were significantly associated with an accurate diagnosis. EUS-FNB using the Franseen needle enables the acquisition of a larger and more adequate histologic core tissue and achieves an accurate histological diagnosis when using the fanning technique. | Yang, Min Jae; Kim, Jaihwan; Park, Se Woo; Cho, Jae Hee; Kim, Eui Joo; Lee, Yun Nah; Lee, Dong Wook; Park, Chan Hyuk; Lee, Sang Soo | Ajou Univ, Dept Gastroenterol, Sch Med, Suwon, South Korea; Seoul Natl Univ, Coll Med, Dept Internal Med, Div Gastroenterol,Bundang Hosp, Seongnam, South Korea; Hallym Univ, Coll Med, Dept Internal Med, Div Gastroenterol,Dongtan Sacred Heart Hosp, 7 Keunjaebong Gil, Hwaseong Si 18450, Gyeonggi Do, South Korea; Yonsei Univ, Gangnam Severance Hosp, Dept Internal Med, Div Gastroenterol,Coll Med, Seoul, South Korea; Gachon Univ, Gil Med Ctr, Dept Internal Med, Div Gastroenterol,Coll Med, Incheon, South Korea; SoonChunHyang Univ, Dept Internal Med, Div Gastroenterol, Sch Med, Bucheon, South Korea; Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu, South Korea; Hanyang Univ, Coll Med, Dept Internal Med, Div Gastroenterol,Guri Hosp, Guri, South Korea; Univ Ulsan, Asan Med Ctr, Dept Gastroenterol, Coll Med, Seoul, South Korea | Cho, Jae Hee/AAL-8192-2020; Lee, Yun/J-1260-2014; Kim, Eui/P-8348-2019; 김, 수중/JED-7162-2023 | 55964785900; 35310739500; 57145012800; 58838319500; 36102878900; 57129189700; 57202974895; 57222484476; 57203597323 | mdsewoopark@gmail.com; | SCIENTIFIC REPORTS | SCI REP-UK | 2045-2322 | 13 | 1 | SCIE | MULTIDISCIPLINARY SCIENCES | 2023 | 3.8 | 18.3 | 1.18 | 2025-06-25 | 9 | 10 | ASPIRATION; MANAGEMENT; PROCORE; IMPACT; TRIAL | Biopsy, Fine-Needle; Endosonography; Humans; Needles; Retrospective Studies; Ultrasonography, Interventional; clinical trial; endoscopic ultrasonography; fine needle aspiration biopsy; human; interventional ultrasonography; multicenter study; needle; retrospective study | English | 2023 | 2023-03-04 | 10.1038/s41598-023-30920-5 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | Article | Comprehensive constitutive modeling and analysis of multi-elastic polydimethylsiloxane (PDMS) for wearable device simulations | Within the field of wearable devices, polydimethylsiloxane (PDMS) has long been one of the most prominent materials utilized. It is therefore unsurprising that demands for its usage has now extended beyond experimental works into computational simulations, particularly those involving finite element method (FEM). To replicate the mechanical properties of PDMS in FEM, an accurate constitutive model is required, preferably one that encompasses wide ranges of PDMS elasticity. In this study, we determine Mooney–Rivlin 5 parameters as the best hyperelastic model fitted against PDMS experimental data, and proceed to construct a parameter correlation plot combining PDMS of different elasticities together. Experimental validation using PDMS samples fabricated via 3D-printed molds is then performed using parameters extracted from this plot, showing good agreement between simulation and experimental result. In addition, to reflect model applicability, simulations related to basic mechanical deformations involved in flexible devices (compression, stretching, bending and twisting) are performed and analyzed. Further analysis is also performed to investigate the effect of combining different experimental datasets as input into the model. We expect our work to be potentially helpful to be applied as both framework and database for wearable device engineers and researchers who are experimenting with varying PDMS concentrations and modulus. © 2023, The Author(s). | Zulkifli, Nora Asyikin; Moon, Geon Dae; Hyun, Dong Choon; Lee, Sungwon | Department of Physics and Chemistry, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Dalseong-Gun, Daegu, 42988, South Korea; Dongnam Division, Korea Institute of Industrial Technology, Busan, 46938, South Korea; Department of Polymer Science and Engineering, Kyungpook National University (KNU), Daegu, 41566, South Korea; Department of Physics and Chemistry, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Dalseong-Gun, Daegu, 42988, South Korea | 57223429921; 23489708500; 15834575400; 56976186600 | swlee@dgist.ac.kr; | Scientific Reports | SCI REP-UK | 2045-2322 | 2045-2322 | 13 | 1 | SCIE | MULTIDISCIPLINARY SCIENCES | 2023 | 3.8 | 18.3 | 2.12 | 2025-06-25 | 18 | English | Final | 2023 | 10.1038/s41598-023-45372-0 | 바로가기 | 바로가기 | 바로가기 | |||||||||
| ○ | ○ | Article | Correlates of burnout among healthcare workers during the COVID-19 pandemic in South Korea | Burnout is a form of negative emotional and physical response to job stress. This study aimed to investigate the prevalence of burnout among healthcare workers responding to the coronavirus disease 2019 (COVID-19) outbreak in Korea and to explore correlates of burnout among healthcare workers. A nationwide questionnaire-based survey was conducted from December 1, 2020, to January 29, 2021 on 1425 healthcare workers who worked in one of the 16 healthcare facilities designated for COVID-19 care, in public health centers, or as paramedics in Korea. Burnout was assessed using 16 Korean-adapted items based on the Oldenburg Burnout Inventory (OLBI). Data were collected using a structured questionnaire and analyzed using the R version 4.1.1 software program. OLBI results indicate clinically exhaustion in 84.5% (1204/1425) and clinically disengagement in 91.1% (1298/1425), and 77.3% (1102/1425) met the score criteria for both the exhaustion and disengagement subscales for burnout. Burnout rate was significantly increased in the group with chronic fatigue symptoms (Fatigue Severity Scale >= 3.22) after the outbreak of COVID-19 (OR, 3.94; 95% CI 2.80-5.56), in the female group (OR, 2.05; 95% CI 1.46-2.86), in the group with physical symptoms (Patient Health Questionnaire-15 >= 10) after the outbreak of COVID-19 (OR, 2.03; 95% CI 1.14-3.60), in the group with a higher Global Assessment of Recent Stress scale (OR, 1.71; 95% CI 1.46-2.01), in the group with post-traumatic stress symptoms (Primary Care Post-Traumatic Stress Disorder-5 >= 2) (OR, 1.47; 95% CI 1.08-2.01), and in the younger age group(OR, 1.45; 95% CI 1.22-1.72). The chronic fatigue symptoms were correlated with cumulative days of care (OR, 1.18; 95% CI 1.02-1.37). The physical symptoms were correlated with average contact hours with COVID-19 patients per day (OR, 1.34; 95% CI 1.17-1.54), and cumulative days of care (OR, 1.21; 95% CI 1.06-1.38). Most Korean healthcare workers suffered from burnout related to excessive workload during the COVID-19 pandemic. During a widespread health crisis like COVID-19, it is necessary to regularly check the burnout status in healthcare workers and reduce their excessive workload by supplementing the workforce and providing appropriate working hours sufficient rest hours. | Hwang, Soyoon; Kwon, Ki Tae; Lee, So Hee; Kim, Shin-Woo; Chang, Hyun-Ha; Kim, Yoonjung; Bae, Sohyun; Cheong, Hae Suk; Park, Se Yoon; Kim, Bongyoung; Lee, Shinwon; Park, Jiho; Heo, Sang Taek; Oh, Won Sup; Kim, Yeonjae; Park, Kyung-Hwa; Kang, Chang Kyung; Oh, NamHee; Lim, Su Jin; Yun, Seongcheol; Son, Ji Woong; Ryoo, Hyun Wook; Chung, Un Sun; Lee, Ju-Yeon; Park, Hye Yoon; Shin, Ji-Yeon; Bae, Sang-geun; Lee, Ji-yeon | Kyungpook Natl Univ, Chilgok Hosp, Sch Med, Dept Internal Med,Div Infect Dis, 807 Hokuk Ro, Daegu 41404, South Korea; Natl Med Ctr, Dept Psychiat, 245 Eulji Ro, Seoul 04564, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Internal Med,Div Infect Dis, Daegu, South Korea; Sungkyunkwan Univ, Kangbuk Samsung Hosp, Dept Internal Med, Div Infect Dis,Sch Med, Seoul, South Korea; Soonchunhyang Univ, Coll Med, Dept Internal Med, Div Infect Dis,Seoul Hosp, Seoul, South Korea; Hanyang Univ, Dept Internal Med, Coll Med, Seoul, South Korea; Pusan Natl Univ, Sch Med, Dept Internal Med, Pusan, South Korea; Pusan Natl Univ Hosp, Med Res Inst, Pusan, South Korea; Konkuk Univ, Med Ctr, Dept Internal Med, Sch Med, Seoul, South Korea; Jeju Natl Univ, Coll Med, Dept Internal Med, Div Infect Dis, Jeju, South Korea; Kangwon Natl Univ, Dept Internal Med, Div Infect Dis, Sch Med, Chunchon, South Korea; Natl Med Ctr, Dept Internal Med, Div Infect Dis, Seoul, South Korea; Chonnam Natl Univ, Dept Infect Dis, Med Sch, Gwangju, South Korea; Seoul Natl Univ, Dept Internal Med, Coll Med, Seoul, South Korea; Daegu Med Ctr, Hosp Infect Control Team, Daegu, South Korea; Masan Med Ctr, Dept Internal Med, Div Resp Dis, Chang Won, South Korea; Andong Med Ctr, Dept Internal Med, Andong, South Korea; Konyang Univ Hosp, Dept Internal Med, Daejeon, South Korea; Kyungpook Natl Univ, Sch Med, Dept Emergency Med, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Psychiat, Daegu, South Korea; Chonnam Natl Univ, Dept Psychiat, Med Sch, Gwangju, South Korea; Seoul Natl Univ Hosp, Dept Psychiat, Seoul, South Korea; Kyungpook Natl Univ, Sch Med, Dept Prevent Med, Daegu, South Korea; Hankuk Univ Foreign Studies, Dept Counseling Psychol, Seoul, South Korea | Kim, Wonhee/AAA-1074-2021; Kim, Jung/S-5543-2017; Lee, So Hee/B-5940-2016; Kim, Woo/AAG-1822-2019; Kim, Hanjin/KYP-2633-2024; Lee, Jung-Seok/L-6826-2019 | 57203160675; 9733850500; 56442744300; 57189703358; 7407521688; 57203160508; 57219699506; 57233155100; 55259986400; 55622077200; 24479446100; 57452625000; 9737963500; 24778642500; 56066688300; 57219637574; 55808491400; 57195674103; 57222279275; 57218948065; 57217473793; 55350557500; 24477437300; 57203144588; 57189505933; 55567961600; 55278023500; 57201650869 | ktkwon@knu.ac.kr;sohee.lee@nmc.or.kr; | SCIENTIFIC REPORTS | SCI REP-UK | 2045-2322 | 13 | 1 | SCIE | MULTIDISCIPLINARY SCIENCES | 2023 | 3.8 | 18.3 | 1.77 | 2025-06-25 | 14 | 15 | ANXIETY DISORDERS; SEVERITY; VALIDATION; VALIDITY; VERSION; NURSES | Burnout, Psychological; COVID-19; Fatigue Syndrome, Chronic; Female; Health Personnel; Humans; Pandemics; Republic of Korea; chronic fatigue syndrome; epidemiology; female; health care personnel; human; pandemic; South Korea | English | 2023 | 2023-02-27 | 10.1038/s41598-023-30372-x | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Cost-effectiveness analysis of COVID-19 variants effects in an age-structured model | This study analyzes the impact of COVID-19 variants on cost-effectiveness across age groups, considering vaccination efforts and nonpharmaceutical interventions in Republic of Korea. We aim to assess the costs needed to reduce COVID-19 cases and deaths using age-structured model. The proposed age-structured model analyzes COVID-19 transmission dynamics, evaluates vaccination effectiveness, and assesses the impact of the Delta and Omicron variants. The model is fitted using data from the Republic of Korea between February 2021 and November 2022. The cost-effectiveness of interventions, medical costs, and the cost of death for different age groups are evaluated through analysis. The impact of different variants on cases and deaths is also analyzed, with the Omicron variant increasing transmission rates and decreasing case-fatality rates compared to the Delta variant. The cost of interventions and deaths is higher for older age groups during both outbreaks, with the Omicron outbreak resulting in a higher overall cost due to increased medical costs and interventions. This analysis shows that the daily cost per person for both the Delta and Omicron variants falls within a similar range of approximately $10-$35. This highlights the importance of conducting cost-effect analyses when evaluating the impact of COVID-19 variants. | Cho, Giphil; Kim, Young Jin; Seo, Sang-hyup; Jang, Geunsoo; Lee, Hyojung | Kangwon Natl Univ, Dept Artificial Intelligence & Software, Chunchon 25913, Gangwon, South Korea; Korea Inst Sci & Technol Informat KISTI, Div Data Anal, Ctr Global R&D Data Anal, Seoul 02456, South Korea; Natl Inst Math Sci, Daejeon 34047, South Korea; Kyungpook Natl Univ, Nonlinear Dynam & Math Applicat Ctr, Daegu 41566, South Korea; Kyungpook Natl Univ, Dept Stat, Daegu 41566, South Korea | 56665111500; 58613860200; 57976073900; 57471384400; 57196021198 | hjlee@knu.ac.kr; | SCIENTIFIC REPORTS | SCI REP-UK | 2045-2322 | 13 | 1 | SCIE | MULTIDISCIPLINARY SCIENCES | 2023 | 3.8 | 18.3 | 0.47 | 2025-06-25 | 5 | 4 | Aged; Cost-Effectiveness Analysis; Costs and Cost Analysis; COVID-19; Humans; SARS-CoV-2; SARS-CoV-2 variants; aged; coronavirus disease 2019; cost; cost effectiveness analysis; human; Severe acute respiratory syndrome coronavirus 2 | English | 2023 | 2023-09-22 | 10.1038/s41598-023-41876-x | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||||
| ○ | ○ | Article | Deep learning system for automated detection of posterior ligamentous complex injury in patients with thoracolumbar fracture on MRI | This study aimed to develop a deep learning (DL) algorithm for automated detection and localization of posterior ligamentous complex (PLC) injury in patients with acute thoracolumbar (TL) fracture on magnetic resonance imaging (MRI) and evaluate its diagnostic performance. In this retrospective multicenter study, using midline sagittal T2-weighted image with fracture (+/- PLC injury), a training dataset and internal and external validation sets of 300, 100, and 100 patients, were constructed with equal numbers of injured and normal PLCs. The DL algorithm was developed through two steps (Attention U-net and Inception-ResNet-V2). We evaluate the diagnostic performance for PLC injury between the DL algorithm and radiologists with different levels of experience. The area under the curves (AUCs) generated by the DL algorithm were 0.928, 0.916 for internal and external validations, and by two radiologists for observer performance test were 0.930, 0.830, respectively. Although no significant difference was found in diagnosing PLC injury between the DL algorithm and radiologists, the DL algorithm exhibited a trend of higher AUC than the radiology trainee. Notably, the radiology trainee's diagnostic performance significantly improved with DL algorithm assistance. Therefore, the DL algorithm exhibited high diagnostic performance in detecting PLC injuries in acute TL fractures. | Jo, Sang Won; Khil, Eun Kyung; Lee, Kyoung Yeon; Choi, Il; Yoon, Yu Sung; Cha, Jang Gyu; Lee, Jae Hyeok; Kim, Hyunggi; Lee, Sun Yeop | Hallym Univ, Dept Radiol, Dongtan Sacred Heart Hosp, 7 Keunjaebong gil, Hwaseong si, South Korea; Fastbone Orthoped Hosp, Dept Radiol, Hwaseong si, South Korea; Hallym Univ, Dept Neurol Surg, Dongtan Sacred Heart Hosp, Hwaseong si, South Korea; Soonchunhyang Univ, Dept Radiol, Bucheon Hosp, Bucheon, South Korea; Kyungpook Natl Univ Hosp, Dept Radiol, Daegu, South Korea; DEEPNOID Inc, Seoul, South Korea | Cha, Jang/U-3216-2019; Lee, Sunyeop/ABB-6576-2021; Choi, IL/ABI-4106-2020; Jo, Sang Won/AAE-7529-2022 | 57203368124; 56019764100; 57789283600; 57188627119; 57414392900; 16027832300; 59448690200; 58295731000; 58295080400 | nizzinim@gmail.com; | SCIENTIFIC REPORTS | SCI REP-UK | 2045-2322 | 13 | 1 | SCIE | MULTIDISCIPLINARY SCIENCES | 2023 | 3.8 | 18.3 | 0.47 | 2025-06-25 | 2 | 4 | VERTEBRAL FRACTURES; SPINE; CLASSIFICATION; MORPHOLOGY; INTEGRITY; SURGEON; TRAUMA | Deep Learning; Fractures, Bone; Humans; Ligaments; Lumbar Vertebrae; Magnetic Resonance Imaging; Retrospective Studies; Thoracic Vertebrae; clinical trial; deep learning; fracture; human; ligament; lumbar vertebra; multicenter study; nuclear magnetic resonance imaging; pathology; procedures; retrospective study; thoracic vertebra | English | 2023 | 2023-11-03 | 10.1038/s41598-023-46208-7 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Demonstration of a roll-to-roll-configurable, all-solution-based progressive assembly of flexible transducer devices consisting of functional nanowires on micropatterned electrodes | We demonstrate continuous fabrication of flexible transducer devices consisting of interdigitated (IDT) Ag microelectrodes interconnected by ZnO nanowires (ZNWs), created via serially connected solution-processable micro- and nanofabrication processes. On an Ag layer obtainable from the mild thermal reduction of an ionic Ag ink coating, the roll-to-roll-driven photolithography process [termed photo roll lithography (PRL)] followed by wet-etching can be applied to continuously define the IDT microelectrode structure. Conformal ZNWs can then be grown selectively on the Ag electrodes to interconnect them via an Ag-mediated hydrothermal ZNW growth that does not require high-temperature seed sintering. Given that all of these constitutive processes are vacuum-free and solution-processable at a low temperature, and are compatible with continuous processing onto flexible substrates, they can be eventually configured into the roll-to-roll-processable progressive assembly. Through parametric optimizations of processes consisting of the roll-to-roll-configurable, solution-based progressive assembly of nanostructures (ROLSPAN), a flexible transducer consisting of ZNW-interconnected, PRL-ed IDT Ag electrodes can be developed. This flexible architecture faithfully performs UV sensing as well as optoelectronic transduction. The ROLSPAN concept along with its specific applicability to flexible devices may inspire many diverse functional systems requiring high-throughput low-temperature fabrication over large-area flexible substrates. | Han, Inhui; Song, Jungkeun; Kim, Kwangjun; Kim, Hyein; Son, Hyunji; Kim, Minwook; Lee, Useung; Choi, Kwangjin; Ji, Hojae; Lee, Sung Ho; Kwak, Moon Kyu; Ok, Jong. G. G. | Seoul Natl Univ Sci & Technol, Dept Mech & Automot Engn, 232 Gongneung Ro, Seoul 01811, South Korea; Dong A Univ, Dept Mech Engn, 37 Nakdong Daero 550 Gil, Busan 49315, South Korea; Kyungpook Natl Univ, Sch Mech Engn, 80 Daehak Ro, Daegu 41566, South Korea; Ncoretechnology Inc, 80 Daehak Ro, Daegu 41566, South Korea | Kwak, Moon/AGQ-6058-2022; Ok, Jong G./B-2509-2010; Ok, Jong/B-2509-2010 | 57450623900; 57223933579; 57217865538; 57468313800; 57560413000; 57217874131; 57884951500; 57450987200; 58314897500; 56195582600; 57203947984; 16480899100 | sunghol@dau.ac.kr;mkkwak@knu.ac.kr;jgok@seoultech.ac.kr; | SCIENTIFIC REPORTS | SCI REP-UK | 2045-2322 | 13 | 1 | SCIE | MULTIDISCIPLINARY SCIENCES | 2023 | 3.8 | 18.3 | 0.24 | 2025-06-25 | 3 | 3 | ARCHITECTURES; PERFORMANCE | English | 2023 | 2023-07-24 | 10.1038/s41598-023-38635-3 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||||
| ○ | ○ | Article | Effect of characteristics on the clinical course at the initiation of treatment for human immunodeficiency virus infection using dimensionality reduction | The beginning of human immunodeficiency virus (HIV) infection treatment depends on various factors, which are significantly correlated with the initial CD4 cell number. However, a covariate correlation between these factors may not reflect the correct outcome variable. Thus, we evaluated the effects of a combination of fixed factors (reduced dimensions), which determine when to start treatment for the first time, on short-term outcome, long-term outcome, and survival, considering correlations between factors. Multiple correspondence analysis was performed on variables obtained from 925 patients who participated in a Korean HIV/acquired immunodeficiency syndrome cohort study (2006-2017). Five reduced dimension groups were derived according to clinical data, viral load, CD4 cell count at diagnosis, initial antiretroviral therapy, and others. The dimension group with high initial viral loads (55,000 copies/mL) and low CD4 cell counts ( 350 cells/mm(3)) that did not require immediate treatment according to previous guidelines had a higher failure rate for long-term relative CD4 recovery. Our results highlight the importance of early diagnosis and treatment to positively influence long-term disease outcomes, even if the initial immune status is poor, given the patient's combination of early diagnostic symptoms. | Choi, Yunsu; Choi, Bo Youl; Kim, Sang Il; Choi, Jungsoon; Kim, Jieun; Park, Bo Young; Kim, Soo Min; Kim, Shin-Woo; Choi, Jun Yong; Song, Joon Young; Kim, Youn Jeong; Kim, Hyo Youl; Lee, Jin-Soo; Kim, Jung Ho; Jun, Yoon Hee; Lee, Myungsun; Seong, Jaehyun | Hanyang Univ, Coll Med, Dept Prevent Med, Seoul, South Korea; Hanyang Univ, Inst Hlth & Soc, Coll Med, Seoul, South Korea; Catholic Univ Korea, Seoul St Marys Hosp, Coll Med, Dept Internal Med,Div Infect Dis, Seoul St, Seoul, South Korea; Hanyang Univ, Dept Math, Seoul, South Korea; Hanyang Univ, Guri Hosp, Coll Med, Dept Internal Med, Guri, South Korea; Yonsei Univ, Coll Commerce & Econ, Dept Stat & Data Sci, Seoul, South Korea; Yonsei Univ, Coll Commerce & Econ, Dept Appl Stat, Seoul, South Korea; Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu, South Korea; Yonsei Univ, Coll Med, AIDS Res Inst, Dept Internal Med, Seoul, South Korea; Korea Univ, Coll Med, Dept Internal Med, Seoul, South Korea; Catholic Univ Korea, Incheon St Marys Hosp, Coll Med, Dept Internal Med,Div Infect Dis, Incheon St, Seoul, South Korea; Yonsei Univ Wonju, Coll Med, Dept Internal Med, Wonju, South Korea; Inha Univ, 22212, Dept Internal Med, Div Infect Dis, Incheon, South Korea; Natl Inst Infect Dis, Korea Natl Inst Hlth KNIH, Ctr Emerging Virus Res, Div Clin Res, Cheongju, South Korea | ; Kim, Jieun/P-1612-2015; Kim, Jung/L-9791-2019; choi, jo/O-5940-2014; Choi, Yunsu/AAH-1260-2021; Kim, Sara/F-2951-2013; Kim, Junetae/AAS-1234-2021; Kim, Ik-Sang/J-5425-2012; Choi, Jah/AAA-4835-2022; Kim, Jong/AAH-5295-2020 | 57195931031; 57236918400; 56941143600; 56050936700; 51963871600; 57217335056; 57194701617; 8710731500; 57791298700; 57214400146; 26659471500; 56819456800; 56162297100; 56657199800; 55187716200; 58603003300; 57207936392 | bychoi@hanyang.ac.kr; | SCIENTIFIC REPORTS | SCI REP-UK | 2045-2322 | 13 | 1 | SCIE | MULTIDISCIPLINARY SCIENCES | 2023 | 3.8 | 18.3 | 0.24 | 2025-06-25 | 2 | 2 | ACTIVE ANTIRETROVIRAL THERAPY; HIV-INFECTION; ADULTS; RECOMMENDATIONS; MULTIVARIATE; PREVENTION; HAART; DRUGS | Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Cohort Studies; Disease Progression; HIV Infections; Humans; Viral Load; anti human immunodeficiency virus agent; acquired immune deficiency syndrome; CD4 lymphocyte count; cohort analysis; disease exacerbation; highly active antiretroviral therapy; human; Human immunodeficiency virus infection; virus load | English | 2023 | 2023-04-04 | 10.1038/s41598-023-31916-x | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Effect of external subretinal fluid drainage on persistent subretinal fluid after scleral buckle surgery in macula-involving rhegmatogenous retinal detachment | This study aimed to analyze the duration and causes of persistent subretinal fluid (PSF) after scleral buckle (SB) surgery in patients with macula-involving rhegmatogenous retinal detachment (RRD). Sixty-one eyes of 61 patients with macula-involving RRD who underwent SB surgery between 2016 and 2022 were reviewed retrospectively. PSF was confirmed on optical coherence tomography. The PSF duration after surgery and the analysis of relevant ocular and systemic factors were conducted according to the PSF duration. The mean duration of PSF was 5.9 +/- 4.6 months in all eyes and 8.1 +/- 5.0 months in eyes not treated with external subretinal fluid (SRF) drainage, which was significantly longer than 4.5 +/- 3.7 months in those subjected to external SRF drainage. The mean best-corrected visual acuity improved significantly 3 months after surgery. There were significant visual improvements in the external SRF drainage group compared to the non-drainage group during all follow-up periods. Longstanding shallow RRD was significantly associated with longer PSF duration after SB surgery. External SRF drainage during SB surgery can effectively reduce SRF, shorten the duration of PSF, and accelerate visual improvement. | Do, Jae Rok; Park, Dong Ho; Shin, Jae Pil; Kang, Yong Koo | Kyungpook Natl Univ, Sch Med, Dept Ophthalmol, Daegu, South Korea; Nune Eye Hosp, Dept Ophthalmol, Daegu, South Korea | ; KANG, YONG KOO/IVH-8723-2023 | 58600232100; 36676632900; 56517350400; 57204703736 | kykyuri@gmail.com; | SCIENTIFIC REPORTS | SCI REP-UK | 2045-2322 | 13 | 1 | SCIE | MULTIDISCIPLINARY SCIENCES | 2023 | 3.8 | 18.3 | 0.12 | 2025-06-25 | 1 | 1 | OPTICAL COHERENCE TOMOGRAPHY; SUBMACULAR FLUID; REATTACHMENT; VITRECTOMY | Drainage; Humans; Retinal Detachment; Retrospective Studies; Scleral Buckling; Subretinal Fluid; Tomography, Optical Coherence; Visual Acuity; Vitrectomy; human; optical coherence tomography; procedures; retina detachment; retrospective study; sclera buckling procedure; subretinal fluid; visual acuity; vitrectomy | English | 2023 | 2023-12-13 | 10.1038/s41598-023-49719-5 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Establishment and characterization of matched immortalized human frontal and occipital scalp dermal papilla cell lines from androgenetic alopecia | Androgenetic alopecia (AGA), also known as male pattern baldness, is a common hair loss condition influenced by genetic and hormonal factors. Variations in gene expression and androgen responsiveness have been observed between the frontal and occipital regions of AGA patients. However, obtaining and cultivating frontal hair follicles is challenging. Therefore, no matched frontal and occipital dermal papilla (DP) cell lines have been reported yet. This study aimed to establish matched immortalized human frontal and occipital scalp DP cell lines from AGA patients. Simian virus 40 large T antigen (SV40T-Ag) and human telomerase reverse transcriptase (hTERT) were introduced into primary human DP cells. The obtained cell lines were characterized by assessing their gene expression patterns, androgen receptor (AR) levels, and the presence of 5-alpha reductase (5 alpha R). Additionally, we examined their response to dihydrotestosterone (DHT) and evaluated cell viability. The conditioned medium from the frontal DP cell line inhibited human hair follicle growth, leading to reduced keratinocyte proliferation and increased apoptosis. Furthermore, when the cells were cultured in a 3D environment mimicking in vivo conditions, the 3D cultured frontal DP cell line exhibited weaker sphere aggregation than the occipital DP cell line due to the increased expression of matrix metalloproteinase 1 (MMP1), MMP3, and MMP9. Additionally, the expression of DP signature genes was inhibited in the 3D cultured frontal DP cell line. These matched frontal and occipital DP cell lines hold significant potential as valuable resources for research on hair loss. Their establishment allows us to investigate the differences between frontal and occipital DP cells, contributing to a better understanding of the molecular mechanisms underlying AGA. Furthermore, these cell lines may be valuable for developing targeted therapeutic approaches for hair loss conditions. | Kwack, Mi Hee; Hamida, Ons Ben; Kim, Min Kyu; Kim, Moon Kyu; Sung, Young Kwan | Kyungpook Natl Univ, Sch Med, Dept Immunol, 680 Gukchaebosang Ro, Daegu 41944, South Korea; Kyungpook Natl Univ, Sch Med, BK21 FOUR KNU Convergence Educ Program Biomed Sci, Kyungpook Natl Univ Hosp, Daegu, South Korea; Kyungpook Natl Univ Hosp, Hair Transplantat Ctr, Daegu, South Korea | 6507685557; 58628712100; 57208648398; 57199748390; 55663365300 | go3004@knu.ac.kr; | SCIENTIFIC REPORTS | SCI REP-UK | 2045-2322 | 13 | 1 | SCIE | MULTIDISCIPLINARY SCIENCES | 2023 | 3.8 | 18.3 | 0.47 | 2025-06-25 | 4 | 4 | MESENCHYMAL-EPITHELIAL INTERACTIONS; HAIR FOLLICLE DEVELOPMENT; MOLECULAR MECHANISMS; GROWTH-FACTOR; IN-VIVO; EXPRESSION; 5-ALPHA-REDUCTASE; PROLIFERATION; CULTURE | Alopecia; Androgens; Cell Line; Hair Follicle; Humans; Male; Scalp; androgen; alopecia; cell line; genetics; hair follicle; human; male; metabolism; scalp | English | 2023 | 2023-12-05 | 10.1038/s41598-023-48942-4 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||||
| ○ | Article | Evaluating anti-thymocyte globulin induction doses for better allograft and patient survival in Asian kidney transplant recipients | Anti-thymocyte globulin (ATG) is currently the most widely prescribed induction regimen for preventing acute rejection after solid organ transplantation. However, the optimal dose of ATG induction regimen in Asian kidney recipients is unclear. Using the Korean Organ Transplantation Registry, we performed a retrospective cohort study of 4579 adult patients who received renal transplantation in South Korea and divided them into three groups according to the induction regimen: basiliximab group (n = 3655), low-dose ATG group (≤ 4.5 mg/kg; n = 467), and high-dose ATG group (> 4.5 mg/kg; n = 457). We applied the Toolkit for Weighting and Analysis of Nonequivalent Groups (TWANG) package to generate high-quality propensity score weights for intergroup comparisons. During four-year follow-ups, the high-dose ATG group had the highest biopsy-proven acute rejection rate (basiliximab 20.8% vs. low-dose ATG 22.4% vs. high-dose ATG 25.6%; P 4.5 mg/kg) was superior to basiliximab and low-dose ATG induction in terms of graft and patient survival in Asian patients undergoing kidney transplant. © 2023, The Author(s). | Shim, Ye Eun; Ko, Youngmin; Lee, Jung Pyo; Jeon, Jin Seok; Jun, Heungman; Yang, Jaeseok; Kim, Myoung Soo; Lim, Seong Jun; Kwon, Hye Eun; Jung, Joo Hee; Kwon, Hyunwook; Kim, Young Hoon; Lee, Jungbok; Shin, Sung; Kong, Jin Min; Kwon, Oh Jung; Kim, Deok Gie; Jung, Cheol Woong; Kim, Yeong Hoon; Kim, Joong Kyung; Kim, Chan-Duck; Min, Ji Won; Lee, Sik; Park, Yeon Ho; Park, Jae Berm; Park, Jung Hwan; Park, Jong-Won; Ban, Tae Hyun; Song, Sang Heon; Song, Seung Hwan; Shin, Ho Sik; Yang, Chul Woo; Yoon, Hye Eun; Lee, Kang Wook; Lee, Dong Ryeol; Lee, Dong Won; Oh, Jieun; Lee, Sang-Ho; Lee, Su Hyung; Lee, Yu Ho; Lee, Jeong-Hoon; Jeong, Kyung Hwan; Chung, Ku Yong; Lee, Jong Soo; Ki, Ju Man; Chae, Dong-Wan; Choi, Soo Jin Na; Han, Seungyeup; Huh, Kyu Ha | Division of Kidney and Pancreas Transplantation, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, South Korea; Division of Kidney and Pancreas Transplantation, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, South Korea; Department of Nephrology, SMG-SNU Boramae Medical Center, Seoul, South Korea; Department of Internal Medicine, Soonchunhyang University Seoul Hospital, Seoul, South Korea; Department of Surgery, Korea University Anam Hospital, Seoul, South Korea; Division of Nephrology, Department of Internal Medicine, Yonsei University College of Medicine, Severance Hospital, Seoul, South Korea; Department of Surgery, Yonsei University College of Medicine, Seoul, South Korea; Division of Kidney and Pancreas Transplantation, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, South Korea; Division of Kidney and Pancreas Transplantation, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, South Korea; Division of Kidney and Pancreas Transplantation, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, South Korea; Division of Kidney and Pancreas Transplantation, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, South Korea; Division of Kidney and Pancreas Transplantation, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, South Korea; Department of Clinical Epidemiology and Biostatistics, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, South Korea; Division of Kidney and Pancreas Transplantation, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, South Korea; Department of Nephrology, BHS Hanseo Hospital, Busan, South Korea; Department of Surgery, College of Medicine, Han Yang University, Seoul, South Korea; Department of Surgery, Yonsei University Wonju College of Medicine, Wonju Severance Christian Hospital, Wonju, South Korea; Department of Surgery, Korea University Anam Hospital, Seoul, South Korea; Department of Internal Medicine, Inje University Busan Paik Hospital, Busan, South Korea; Department of Internal Medicine, Bongseng Memorial Hospital, Busan, South Korea; Department of Internal Medicine, School of Medicine, Kyungpook National University Hospital, Daegu, South Korea; Division of Nephrology, Department of Internal Medicine, Bucheon St. Mary’s Hospital, Bucheon, South Korea; Department of Internal Medicine, Jeonbuk National University Hospital, Jeonju, South Korea; Department of Surgery, Gil Medical Center, Gachon University College of Medicine, Seoul, South Korea; Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; Department of Nephrology, Konkuk University School of Medicine, Seoul, South Korea; Department of Nephrology, Yeungnam University Hospital, Daegu, South Korea; Division of Nephrology, Department of Internal Medicine, Eunpyeong St. Mary’s Hospital, Seoul, South Korea; Department of Internal Medicine, Pusan National University Hospital, Busan, South Korea; Department of Surgery, Ewha Womans University Seoul Hospital, Seoul, South Korea; Division of Nephrology, Department of Internal Medicine, Kosin University College of Medicine, Busan, South Korea; Division of Nephrology, Department of Internal Medicine, Seoul St. Mary’s Hospital, Seoul, South Korea; Department of Internal Medicine, Incheon St. Mary’s Hospital, College of Medicine, The Catholic University of Korea College of Medicine, Seoul, South Korea; Department of Nephrology, Chungnam National University Hospital, Daejeon, South Korea; Division of Nephrology, Department of Internal Medicine, Maryknoll Medical Center, Hamilton, Australia; Division of Nephrology, Department of Internal Medicine, Pusan National University School of Medicine, Yangsan, South Korea; Department of Internal Medicine, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon, South Korea; Department of Nephrology, Kyung Hee University Hospital at Gangdong, Seoul, South Korea; Department of Surgery, Ajou University School of Medicine, Suwon, South Korea; Division of Nephrology, Department of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, South Korea; Department of Surgery, Myongji Hospital, Goyang, South Korea; Department of Internal Medicine, Kyung Hee University College of Medicine, Seoul, South Korea; Department of Surgery, Ewha Womans University Mokdong Hospital, Seoul, South Korea; Department of Surgery, Ulsan University Hospital, Ulsan, South Korea; Department of Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, South Korea; Division of Nephrology, Seoul National University Bundang Hospital, Seongnam, South Korea; Department of Surgery, Chonnam National University Medical School, Gwangju, South Korea; Department of Internal Medicine, Keimyung University School of Medicine, Daegu, South Korea; Department of Surgery, Yonsei University College of Medicine, Seoul, South Korea | 57221722419; 57210962623; 56028990400; 36120293400; 55508260600; 57212326527; 35268871600; 57219422978; 57924581600; 57158016100; 56306126900; 57281310600; 16202847300; 56160996300; 7202290990; 57252511100; 57198637675; 7402016375; 7410196419; 56508055400; 8558530700; 56212607100; 57192521521; 57189388760; 13605451500; 56682283600; 54955660800; 56119751700; 36162581500; 57226657760; 57216238599; 7407743404; 57737628900; 7501514537; 57218150487; 57199467944; 8409118400; 55890136000; 57307240100; 56344334200; 57218629097; 8443579300; 24773386100; 57201264463; 57220162686; 57964963700; 35784016900; 24281360600; 35183155900 | sshin@amc.seoul.kr;jungbok.lee@gmail.com; | Scientific Reports | SCI REP-UK | 2045-2322 | 2045-2322 | 13 | 1 | SCIE | MULTIDISCIPLINARY SCIENCES | 2023 | 3.8 | 18.3 | 0.12 | 2025-06-25 | 1 | Adult; Allografts; Antibodies, Monoclonal; Antilymphocyte Serum; Basiliximab; Graft Rejection; Graft Survival; Humans; Immunosuppressive Agents; Kidney Transplantation; Retrospective Studies; basiliximab; immunosuppressive agent; lymphocyte antibody; monoclonal antibody; adult; allograft; graft rejection; graft survival; human; kidney transplantation; procedures; retrospective study | English | Final | 2023 | 10.1038/s41598-023-39353-6 | 바로가기 | 바로가기 | 바로가기 | ||||||||
| ○ | ○ | Article | Fabrication of THz corrugated wakefield structure and its high power test | We present overall process for developing terahertz (THz) corrugated structure and its beam-based measurement results. 0.2-THz corrugated structures were fabricated by die stamping method as the first step demonstration towards GW THz radiation source and GV/m THz wakefield accelerator. 150-mu m thick disks were produced from an OFHC (C10100) foil by stamping. Two types of disks were stacked alternately to form 46 mm structure with similar to 170 corrugations. Custom assembly was designed to provide diffusion bonding with a high precision alignment of disks. The compliance of the fabricated structure have been verified through beam-based wakefield measurement at Argonne Wakefield Accelerator Facility. Both measured longitudinal and transverse wakefield showed good agreement with simulated wakefields. Measured peak gradients, 9.4 MV/m/nC for a long single bunch and 35.4 MV/m/nC for a four bunch trains, showed good agreement with the simulation. | Kong, H.; Chung, M.; Doran, D. S.; Ha, G.; Kim, S. -H.; Kim, J. -H.; Liu, W.; Lu, X.; Power, J.; Seok, J. -M.; Shin, S.; Shao, J.; Whiteford, C.; Wisniewski, E. | Pohang Accelerator Lab, POSTECH, Pohang 37673, Gyungbuk, South Korea; Kyungpook Natl Univ, Dept Phys, Daegu 41566, South Korea; Ulsan Natl Inst Sci & Technol, Ulsan 44919, South Korea; Argonne Natl Lab, Argonne, IL 60439 USA; Northern Illinois Univ, De Kalb, IL 60115 USA; Korea Univ, Dept Accelerator Sci, Sejong 30019, South Korea | Ha, Gwanghui/JQJ-4885-2023 | 58485063000; 56531262200; 55884600900; 55254224300; 58979810800; 59087571400; 7407342235; 57008462100; 56854811300; 57193629960; 36438852000; 55580271900; 56604020400; 55612470200 | tlssh@korea.ac.kr; | SCIENTIFIC REPORTS | SCI REP-UK | 2045-2322 | 13 | 1 | SCIE | MULTIDISCIPLINARY SCIENCES | 2023 | 3.8 | 18.3 | 0.35 | 2025-06-25 | 4 | 3 | article; diffusion; simulation; terahertz radiation | English | 2023 | 2023-02-24 | 10.1038/s41598-023-29997-9 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||||
| ○ | ○ | Correction | Fabrication of THz corrugated wakefield structure and its high power test (vol 13, 3207, 2023) | Kong, H.; Chung, M.; Doran, D. S.; Ha, G.; Kim, S. -H.; Kim, J. -H.; Liu, W.; Lu, X.; Power, J.; Seok, J. -M.; Shin, S.; Shao, J.; Whiteford, C.; Wisniewski, E. | Pohang Accelerator Lab, Pohang 37673, Gyungbuk, South Korea; Kyungpook Natl Univ, Dept Phys, Daegu 41566, South Korea; Ulsan Natl Inst Sci & Technol, Ulsan 44919, South Korea; Argonne Natl Lab, Argonne, IL 60439 USA; Northern Illinois Univ, De Kalb, IL 60115 USA; Korea Univ, Dept Accelerator Sci, Sejong 30019, South Korea | Ha, Gwanghui/JQJ-4885-2023 | 58485063000; 56531262200; 55884600900; 55254224300; 58979810800; 59087571400; 7407342235; 57008462100; 56854811300; 57193629960; 36438852000; 55580271900; 56604020400; 55612470200 | gwanghui.ha@gmail.com;tlssh@korea.ac.kr; | SCIENTIFIC REPORTS | SCI REP-UK | 2045-2322 | 13 | 1 | SCIE | MULTIDISCIPLINARY SCIENCES | 2023 | 3.8 | 18.3 | 0 | 2025-06-25 | 0 | 0 | erratum | English | 2023 | 2023-03-14 | 10.1038/s41598-023-31386-1 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||||
| ○ | Article | Family history, socioeconomic factors, comorbidities, health behaviors, and the risk of sudden cardiac arrest | Genetic, environment, and behaviour factors have a role in causing sudden cardiac arrest (SCA). We aimed to determine the strength of the association between various risk factors and SCA incidence. We conducted a multicentre case-control study at 17 hospitals in Korea from September 2017 to December 2020. The cases included out-of-hospital cardiac arrest aged 19–79 years with presumed cardiac aetiology. Community-based controls were recruited at a 1:1 ratio after matching for age, sex, and urban residence level. Multivariable conditional logistic regression analysis was conducted. Among the 1016 cases and 1731 controls, 948 cases and 948 controls were analysed. A parental history of SCA, low educational level, own heart disease, current smoking, and non-regular exercise were associated with SCA incidence (Adjusted odds ratio [95% confidence interval]: 2.51 [1.48–4.28] for parental history of SCA, 1.37 [1.38–2.25] for low edication level, 3.77 [2.38–5.90] for non-coronary artery heart disease, 4.47 [2.84–7.03] for coronary artery disease, 1.39 [1.08–1.79] for current smoking, and 4.06 [3.29–5.02] for non-regular exercise). Various risk factors related to genetics, environment, and behaviour were independently associated with the incidence of SCA. Establishing individualised SCA prevention strategies in addition to general prevention strategies is warranted. © 2023, The Author(s). | Jung, Eujene; Park, Jeong Ho; Ro, Young Sun; Ryu, Hyun Ho; Cha, Kyoung-Chul; Do Shin, Sang; Hwang, Sung Oh; Do Shin, Sang; Lee, Mi Jin; Park, Jong-Hak; Kim, Su Jin; Oh, Sung Bum; Shin, Jonghwan; Park, Seung Min; Sim, Min Seob; Kim, Won Young; Park, In-Cheol; You, Yeonho; Kim, Sang-Chul; Park, Ju Ok | Department of Emergency Medicine, Chonnam National University Hospital, Gwangju, South Korea, Laboratory of Emergency Medical Services, Seoul National University Hospital Biomedical Research Institute, Seoul, South Korea; Laboratory of Emergency Medical Services, Seoul National University Hospital Biomedical Research Institute, Seoul, South Korea, Department of Emergency Medicine, Seoul National University College of Medicine and Hospital, Seoul, South Korea, Disaster Medicine Research Center, Seoul National University Medical Research Center, Seoul, South Korea; Laboratory of Emergency Medical Services, Seoul National University Hospital Biomedical Research Institute, Seoul, South Korea, Department of Emergency Medicine, Seoul National University College of Medicine and Hospital, Seoul, South Korea, Disaster Medicine Research Center, Seoul National University Medical Research Center, Seoul, South Korea; Department of Emergency Medicine, Chonnam National University Hospital, Gwangju, South Korea, Chonnam National University Hospital, Gwangju, South Korea; Department of Emergency Medicine, Yonsei University Wonju College of Medicine, Wonju, South Korea; Laboratory of Emergency Medical Services, Seoul National University Hospital Biomedical Research Institute, Seoul, South Korea, Department of Emergency Medicine, Seoul National University College of Medicine and Hospital, Seoul, South Korea, Disaster Medicine Research Center, Seoul National University Medical Research Center, Seoul, South Korea; Department of Emergency Medicine, Yonsei University Wonju College of Medicine, Wonju, South Korea, Yonsei University Wonju Severance Christian Hospital, Wonju-Si, South Korea; Seoul National University Hospital, Seoul, South Korea; Kyungpook National University Hosptial, Daegu, South Korea; Korea University Ansan Hospital, Ansan-Si, South Korea; Korea University Ansan Hospital, Ansan-Si, South Korea; Dankook University Hospital, Cheonan-Si, South Korea; Seoul National University Boramae Medical Center, Seoul, South Korea; Seoul National University Bundang Hospital, Seongnam, South Korea; Sungkyunkwan University Samsung Medical Center, Seoul, South Korea; Ulsan University Asan Medical Center, Seoul, South Korea; Yonsei University Severance Hospital, Seoul, South Korea; Chungnam National University Hospital, Daejeon, South Korea; Chungbuk National University Hospital, Cheongju-Si, South Korea; Hallym University Dongtan Sacred Heart Hospital, Hwaseong-Si, South Korea | 57194543281; 57222635486; 37665990400; 26325849500; 39860962000; 58572934500; 57202063517; 57049712400; 55507282600; 57196407523; 57196044127; 57428640900; 57049712300; 54411205900; 26645185500; 57991503300; 56573250000; 35077217100; 7601581324; 57196406548 | timthe@gmail.com; | Scientific Reports | SCI REP-UK | 2045-2322 | 2045-2322 | 13 | 1 | SCIE | MULTIDISCIPLINARY SCIENCES | 2023 | 3.8 | 18.3 | 0.48 | 2025-06-18 | 4 | Case-Control Studies; Coronary Artery Disease; Death, Sudden, Cardiac; Health Behavior; Heart Diseases; Humans; Out-of-Hospital Cardiac Arrest; Risk Factors; Socioeconomic Factors; case control study; complication; coronary artery disease; health behavior; heart disease; human; out of hospital cardiac arrest; risk factor; socioeconomics; sudden cardiac death | English | Final | 2023 | 10.1038/s41598-023-48357-1 | 바로가기 | 바로가기 | 바로가기 |
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