연구성과로 돌아가기
2022 연구성과 (102 / 280)
※ 컨트롤 + 클릭으로 열별 다중 정렬 가능합니다.
Excel 다운로드
| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ○ | ○ | Article | Simultaneous Extraction of the Grain Size, Single-Crystalline Grain Sheet Resistance, and Grain Boundary Resistivity of Polycrystalline Monolayer Graphene | The electrical properties of polycrystalline graphene grown by chemical vapor deposition (CVD) are determined by grain-related parameters-average grain size, single-crystalline grain sheet resistance, and grain boundary (GB) resistivity. However, extracting these parameters still remains challenging because of the difficulty in observing graphene GBs and decoupling the grain sheet resistance and GB resistivity. In this work, we developed an electrical characterization method that can extract the average grain size, single-crystalline grain sheet resistance, and GB resistivity simultaneously. We observed that the material property, graphene sheet resistance, could depend on the device dimension and developed an analytical resistance model based on the cumulative distribution function of the gamma distribution, explaining the effect of the GB density and distribution in the graphene channel. We applied this model to CVD-grown monolayer graphene by characterizing transmission-line model patterns and simultaneously extracted the average grain size (~5.95 mu m), single-crystalline grain sheet resistance (~321 omega/sq), and GB resistivity (~18.16 k omega-mu m) of the CVD-graphene layer. The extracted values agreed well with those obtained from scanning electron microscopy images of ultraviolet/ozone-treated GBs and the electrical characterization of graphene devices with sub-micrometer channel lengths. | Park, Honghwi; Lee, Junyeong; Lee, Chang-Ju; Kang, Jaewoon; Yun, Jiyeong; Noh, Hyowoong; Park, Minsu; Lee, Jonghyung; Park, Youngjin; Park, Jonghoo; Choi, Muhan; Lee, Sunghwan; Park, Hongsik | Kyungpook Natl Univ, Sch Elect & Elect Engn, Daegu 41566, South Korea; Kyungpook Natl Univ, Sch Elect Engn, Daegu 41566, South Korea; Purdue Univ, Sch Engn Technol, W Lafayette, IN 47907 USA | Lee, Chang-Ju/W-8546-2019; Lee, Sunghwan/J-5424-2014; Park, Honghwi/KIC-1871-2024 | 57206811785; 57210867037; 8943234400; 57207345841; 57402871200; 57209882167; 57402583800; 57227779600; 57227237200; 57196408322; 7402093793; 57192514024; 35366976200 | hoepark@ee.knu.ac.kr;jyl2015@ee.knu.ac.kr;chjlee@knu.ac.kr;jwnkang@knu.ac.kr;yeong112@knu.ac.kr;hwn1327@knu.ac.kr;msp7352@knu.ac.kr;jongh1019@knu.ac.kr;dudwls1218@knu.ac.kr;jonghoopark@knu.ac.kr;mhchoi@ee.knu.ac.kr;sunghlee@purdue.edu;hpark@ee.knu.ac.kr; | NANOMATERIALS | NANOMATERIALS-BASEL | 2079-4991 | 12 | 2 | SCIE | CHEMISTRY, MULTIDISCIPLINARY;MATERIALS SCIENCE, MULTIDISCIPLINARY;NANOSCIENCE & NANOTECHNOLOGY;PHYSICS, APPLIED | 2022 | 5.3 | 24.1 | 0.51 | 2025-06-25 | 6 | 8 | CVD graphene; polycrystalline; grain size; single-crystalline grain; grain boundary (GB); GB distribution; sheet resistance; transmission-line model measurement | ELECTRICAL-TRANSPORT; COPPER; FILMS | CVD graphene; GB distribution; Grain boundary (GB); Grain size; Polycrystalline; Sheet resistance; Single-crystalline grain; Transmission-line model measurement | English | 2022 | 2022-01 | 10.3390/nano12020206 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Editorial Material | Special Issue "Advanced Nanomaterials for Bioimaging" | Lee, Gang Ho | Kyungpook Natl Univ, Coll Nat Sci, Dept Chem, Taegu 41566, South Korea | 7404851841 | ghlee@mail.knu.ac.kr; | NANOMATERIALS | NANOMATERIALS-BASEL | 2079-4991 | 12 | 14 | SCIE | CHEMISTRY, MULTIDISCIPLINARY;MATERIALS SCIENCE, MULTIDISCIPLINARY;NANOSCIENCE & NANOTECHNOLOGY;PHYSICS, APPLIED | 2022 | 5.3 | 24.1 | 0.71 | 2025-06-25 | 0 | 1 | NANOPARTICLES; ACID | English | 2022 | 2022-07 | 10.3390/nano12142496 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||||||
| ○ | ○ | Article | Strategic Electrochemical Determination of Nitrate over Polyaniline/Multi-Walled Carbon Nanotubes-Gum Arabic Architecture | Significant agricultural and industrial activities necessitate the regular monitoring of nitrate (NO3-) ions levels in feed and groundwater. The current comparative study discloses an innovative user-friendly electrochemical approach for the determination of NO3- over polyaniline (PAni)-based modified electrodes. The electrochemical sensors concocted with PAni, multi-walled carbon nanotubes (CNT), and gum arabic (GA). The unique electrode material GA@PAni-CNT was synthesized by facile one-pot catalytic polymerization of aniline (Ani) with FeCl3/H2O2 in the presence of CNT and GA as integral components. As revealed by cyclic voltammetry (CV), the anchoring/retention of NO3- followed by reduction is proposed to occur when a GA@PAniCNT electrode is immersed in phosphate buffer electrolyte containing NO3- that eventually results in a significantly higher redox activity of the GA@PAni-CNT electrode upon potential scan. The mechanism of NO3- anchoring may be associated with the non-redox transition of leucomeraldine salt (LS) into emeraldine salt (ES) and the generation of nitrite (NO2-) ions. As a result, the oxidation current produced by CV for redox transition of ES pernigraniline (PN) was similar to 9 times of that obtained with GA@PAni-CNT electrode and phosphate buffer electrolyte, thus achieving indirect NO3- voltammetric determination of the GA@PAni-CNT electrode. The prepared GA@PAni-CNT electrode displayed a higher charge transfer ability as compared to that of PAni-CNT and PAni electrodes. The optimum square wave voltammetric (SWV) response resulted in two linear concentration ranges of 1-10 (R-2 = 0.9995) and 15-50 mu M (R-2 = 0.9988) with a detection limit of 0.42 mu M, which is significantly lower. The GA@PAni-CNT electrode demonstrated the best detection, sensitivity, and performance among the investigated electrodes for indirect voltammetric determination of NO3- that portrayed the possibility of utilizing GA-stabilized PAni and CNT nanocomposite materials in additional electrochemical sensing applications. | Kosa, Samia Abdulhammed Mohamad; Khan, Amna Nisar; Ahmed, Sana; Aslam, Mohammad; Bawazir, Wafa AbuBaker; Hameed, Abdul; Soomro, Muhammad Tahir | King Abdulaziz Univ, Fac Sci, Dept Chem, Jeddah 21589, Saudi Arabia; King Abdulaziz Univ, Ctr Excellence Environm Studies CEES, Jeddah 21589, Saudi Arabia; Kyungpook Natl Univ, Engn Sch, Dept Appl Chem, Daegu 41566, South Korea; Quaid i Azam Univ, Natl Ctr Phys, Islamabad 44000, Pakistan | Aslam, Mohammad/L-2447-2014; Bawazir, Wafa/AAU-7548-2020; Soomro, Muhammad Tahir/H-2299-2017; Abdul, Hameed/I-8049-2015; Bawazir, Wafa/H-1429-2018; Kosa, Samia/C-2547-2013; Ahmed, Sana/JXL-4930-2024 | 8529118800; 57191855184; 57444624300; 36924424100; 36975187000; 57612641500; 36635020200 | mssoomro@kau.edu.sa; | NANOMATERIALS | NANOMATERIALS-BASEL | 2079-4991 | 12 | 19 | SCIE | CHEMISTRY, MULTIDISCIPLINARY;MATERIALS SCIENCE, MULTIDISCIPLINARY;NANOSCIENCE & NANOTECHNOLOGY;PHYSICS, APPLIED | 2022 | 5.3 | 24.1 | 0.51 | 2025-06-25 | 7 | 7 | polyaniline; multi-walled carbon nanotubes; gum arabic; nitrate determination; voltammetry | PASTE ELECTRODE; COMPOSITE; SENSOR; NANOCOMPOSITES; NITRITE; FILM; SUPERCAPACITORS; CONDUCTIVITY; ENHANCEMENT; STABILITY | gum arabic; multi-walled carbon nanotubes; nitrate determination; polyaniline; voltammetry | English | 2022 | 2022-10 | 10.3390/nano12193542 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Synthesis and Characterization of Monodispersed Spherical Calcium Oxide and Calcium Carbonate Nanoparticles via Simple Pyrolysis | In this study, calcium carbonate nanoparticles (CCNPs) and calcium oxide nanoparticles (CONPs) are synthesized by the carbonization/calcination of calcium oleate. CONPs are an essential inorganic material, and they are used as catalysts and as effective chemisorbents for toxic gases. CCNPs are widely used in plastics, printing ink, and medicines. Here, calcium oleate is used as a starting material for the preparation of CCNPs and CONPs. This calcium oleate is prepared from calcium hydroxide and oleic acid in ethanol under mild reflux conditions. The effect of the calcination temperature of calcium oleate is examined during the synthesis of CCNPs and CONPs. By simple carbonization/calcination, calcite-type CCNPs and CONPs are prepared at 600 degrees C, respectively. The synthesized nanomaterials are analyzed by various physicochemical characterization techniques such as X-ray diffraction (XRD), Fourier transform infrared spectroscopy, thermogravimetric analysis (TGA) with derivative thermogravimetry (DTG), and scanning electron microscopy (SEM) with energy dispersive X-ray analysis. An X-ray diffractometer and the Scherrer formula are used to analyze the crystalline phase and crystallite size of prepared nanoparticles. TGA techniques confirm the thermal stability of the calcium oleate, CCNPs, and CONPs. The SEM analysis illustrates the dispersive behavior and cubic/spherical morphologies of CCNPs/CONPs. Furthermore, the obtained results are compared to the CCNP and CONP samples prepared using calcium hydroxide. As a result, the carbonization/calcination of calcium oleate produces monodispersed CONPs, which are then compared to the CONPs from calcium hydroxide. Additionally, from calcium oleate, CONPs can be prepared on a large scale in a cheap, convenient way, using simple equipment which can be applied in various applications. | Atchudan, Raji; Perumal, Suguna; Joo, Jin; Lee, Yong Rok | Kyungpook Natl Univ, Dept Appl Chem, Daegu 41566, South Korea; Yeungnam Univ, Sch Chem Engn, Gyongsan 38541, South Korea; Saveetha Inst Med & Tech Sci, Saveetha Sch Engn, Dept Chem, Chennai 602105, Tamil Nadu, India; Sejong Univ, Dept Chem, Seoul 143747, South Korea | Lee, Yong/K-6373-2015; RAJI, ATCHUDAN/C-9904-2017; perumal, suguna/N-9075-2017 | 26648054700; 56673798900; 57189617034; 57330662900 | atchudanr@yu.ac.kr;suguna.perumal@gmail.com;joojin@knu.ac.kr;yrlee@yu.ac.kr; | NANOMATERIALS | NANOMATERIALS-BASEL | 2079-4991 | 12 | 14 | SCIE | CHEMISTRY, MULTIDISCIPLINARY;MATERIALS SCIENCE, MULTIDISCIPLINARY;NANOSCIENCE & NANOTECHNOLOGY;PHYSICS, APPLIED | 2022 | 5.3 | 24.1 | 1.16 | 2025-06-25 | 14 | 16 | calcium carbonate; calcium oxide; calcium hydroxide; calcium oleate; carbonization; pyrolysis | CACO3 NANOPARTICLES; CAO NANOPARTICLES; PRECIPITATION; PARTICLES | calcium carbonate; calcium hydroxide; calcium oleate; calcium oxide; carbonization; pyrolysis | English | 2022 | 2022-07 | 10.3390/nano12142424 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Washable Fabric Triboelectric Nanogenerators for Potential Application in Face Masks | In order to counteract the COVID-19 pandemic by wearing face masks, we examine washable fabric-based triboelectric nanogenerators (FTENGs). We applied the flash-spun nonwoven fabric (FS fabric) into the FTENGs, comparing the melt-blown nonwoven fabric (MB fabric) based FTENGs, which is conventionally studied in the field of energy harvesting. For reusability, all our proposed FTENGs are systematically investigated by controlling the washing conditions. After washing, the degradation ratio of the obtained output voltage is found to be only 12.5% for FS FTENGs, compared to the ratio of about 50% for the typical MB FTENGs. A rather small degradation ratio for FS fabric cases has resulted from less changed fabric structure after washing due to more dense fabric nature. Additionally, in order to improve the electrical characteristics of FS FTENGs. Note that the output voltage of FTENGs exhibits as much as 600 V. | Jeon, Sang-Hwa; Lee, Yongju; Biswas, Swarup; Choi, Hyojeong; Han, Selim; Kim, Minseo; Lee, Dong-Wook; Lee, Sohee; Kim, Hyeok; Bae, Jin-Hyuk | Kyungpook Natl Univ, Sch Elect & Elect Engn, Daegu 41566, South Korea; Univ Seoul, Ctr Smart Sensor Syst Seoul CS4, Sch Elect & Comp Engn, Seoul 02504, South Korea; Korea Inst Ind Technol KITECH, AI Robot R&D Dept, Ansan 15588, South Korea; Pusan Natl Univ, Sch Chem Engn, Busan 56241, South Korea; Gyeongsang Natl Univ, Res Inst Nat Sci, Dept Clothing & Text, Jinju 52828, South Korea; Kyungpook Natl Univ, Sch Elect Engn, Daegu 41566, South Korea | Kim, Jin/E-6152-2010; Biswas, Swarup/AAH-5067-2019 | 57552166800; 58552016200; 7402251506; 57915297100; 57914230600; 57807137400; 55516365700; 37056928800; 57191718658; 35326180700 | sohee.lee@gnu.ac.kr;hyeok.kim@uos.ac.kr;jhbae@ee.knu.ac.kr; | NANOMATERIALS | NANOMATERIALS-BASEL | 2079-4991 | 12 | 18 | SCIE | CHEMISTRY, MULTIDISCIPLINARY;MATERIALS SCIENCE, MULTIDISCIPLINARY;NANOSCIENCE & NANOTECHNOLOGY;PHYSICS, APPLIED | 2022 | 5.3 | 24.1 | 0.29 | 2025-06-25 | 4 | 4 | washability; fabric-triboelectric nanogenerators; degradation ratio; elastomer; flash-spun nonwoven | degradation ratio; elastomer; fabric-triboelectric nanogenerators; flash-spun nonwoven; washability | English | 2022 | 2022-09 | 10.3390/nano12183152 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Review | A comprehensive review of heavy metal pollution in the coastal areas of Bangladesh: abundance, bioaccumulation, health implications, and challenges | The coastal zone of Bangladesh, with a population density of 1278 people per square kilometer, is under serious threat due to heavy metal pollution. To date, many studies have been conducted on the heavy metal contamination in soils, water, aquatic animals, and plants in the coastal zone of Bangladesh; however, the available information is dispersed. In this study, previous findings on the contamination levels, distributions, risks, and sources of heavy metals in sediments and organisms were summarized for the first time to present the overall status of heavy metal pollution along coastal regions. Earlier research found that the concentrations of various heavy metals (HMs), particularly Co, Cd, Pb, Cu, Cr, Mn, Fe, and Ni in water, sediment, and fish in most coastal locations, were above their permissible limits. High concentrations of HMs were observed in sediments and water, like Cr of 55 mg/kg and 86.93 mg/l in the ship-breaking areas and Karnaphuli River, respectively, in coastal regions of Bangladesh. Heavy metals severely contaminated the Karnaphuli River estuary and ship-breaking area on the Sitakundu coast, where sediments were the ultimate sink of high concentrations of metals. Sedentary or bottom-dwelling organisms like gastropods and shrimp had higher levels of heavy metals than other organisms. As a result, the modified PRISMA review method was used to look at the critical research gap about heavy metal pollution in Bangladesh's coastal areas by analyzing the current research trends and bottlenecks. | Rakib, Md Refat Jahan; Rahman, Md Asrafur; Onyena, Amarachi Paschaline; Kumar, Rakesh; Sarker, Aniruddha; Hossain, M. Belal; Islam, Abu Reza Md Towfiqul; Islam, Md Saiful; Rahman, Md Mostafizur; Jolly, Yeasmin Nahar; Idris, Abubakr M.; Ali, Mir Mohammad; Bilal, Muhammad; Sun, Xian | Noakhali Sci & Technol Univ, Fac Sci, Dept Fisheries & Marine Sci, Noakhali, Bangladesh; Nigeria Maritime Univ Okerenkoko, Dept Marine Environm & Pollut Control, Warri, Delta State, Nigeria; Nalanda Univ, Sch Ecol & Environm Studies, Rajgir 803116, Bihar, India; Kyungpook Natl Univ, Coll Agr & Life Sci, Sch Appl Biosci, Daegu 41566, South Korea; Griffith Univ, Sch Engn & Built Environm, Brisbane, Qld, Australia; Begum Rokeya Univ, Dept Disaster Management, Rangpur 5400, Bangladesh; Patuakhali Sci & Technol Univ, Dept Soil Sci, Dumki, Patuakhali, Bangladesh; Jahangirnagar Univ, Dept Environm Sci, Lab Environm Hlth & Ecotoxicol, Dhaka 1342, Bangladesh; Atom Energy Ctr, Atmospher & Environm Chem Lab, Chem Div, Dhaka 1000, Bangladesh; King Khalid Univ, Coll Sci, Dept Chem, Abha 62529, Saudi Arabia; King Khalid Univ, Res Ctr Adv Mat Sci RCAMS, Abha 62529, Saudi Arabia; Bangla Agr Univ, Dept Aquaculture, Dhaka 1207, Bangladesh; Huaiyin Inst Technol, Sch Life Sci & Food Engn, Huaian, Peoples R China; Sun Yat Sen Univ, Sch Marine Sci,Southern Marine Sci & Engn Guangdo, Zhuhai Key Lab Marine Bioresources & Environm, Guangdong Prov Key Lab Marine Resources & Coastal, Guangzhou 510275, Peoples R China | Xian, Sun/KBB-6620-2024; Ali, Mir/N-1041-2019; Rakib, Md Refat J./AAD-9711-2021; Idris, Abubakr/JWO-9124-2024; Onyena, Amarachi/AAD-9424-2021; Bilal, Muhammad/LXB-1628-2024; Hossain, Mohammad Belal/AAU-7266-2020; Sarker, Aniruddha/GYQ-6800-2022; Idris, Abubakr/E-6452-2012; Islam, Abu Reza Md. Towfiqul/O-8554-2019; Rahman, Mostafizur/X-7420-2019; Islam, Saiful/I-6354-2013; Kumar, Rakesh/ABA-5632-2020; Hossain, M./AAU-7266-2020 | 57221225845; 57656041900; 57211203885; 57408065700; 57211874397; 54987254000; 57218543677; 55547120952; 57215630235; 6603147401; 57893996600; 57214142357; 57316728100; 57194650751 | rifatjahanrakib@gmail.com; | ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH | ENVIRON SCI POLLUT R | 0944-1344 | 1614-7499 | 29 | 45 | SCIE | ENVIRONMENTAL SCIENCES | 2022 | 5.8 | 24.2 | 2.11 | 2025-06-25 | 76 | 85 | Heavy metals; Sediment; Ecological risk; Coastal Bangladesh; Environmental remediation | SHIP BREAKING AREA; RISK-ASSESSMENT; TRACE-ELEMENTS; RIVER ESTUARY; SURFACE SEDIMENTS; ECOLOGICAL RISK; SPATIAL-DISTRIBUTION; SEASONAL-VARIATION; KARNAFULLY RIVER; BURIGANGA RIVER | Coastal Bangladesh; Ecological risk; Environmental remediation; Heavy metals; Sediment | Bangladesh; Bioaccumulation; Cadmium; China; Environmental Monitoring; Geologic Sediments; Humans; Lead; Metals, Heavy; Risk Assessment; Rivers; Soil; Water; Water Pollutants, Chemical; Bangladesh; cadmium; heavy metal; lead; water; bioaccumulation; coastal zone; concentration (composition); environmental technology; gastropod; health impact; heavy metal; literature review; pollution effect; risk assessment; sediment pollution; Bangladesh; bioaccumulation; China; environmental monitoring; human; procedures; risk assessment; river; sediment; soil; water pollutant | English | 2022 | 2022-09 | 10.1007/s11356-022-22122-9 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | A pilot study for enhanced transformation of a metabolite 3,5-dichloroaniline derived from dicarboximide fungicides through immobilized laccase mediator system | This pilot investigation aimed to evaluate the removal efficiency and the underlying biocatalytic pathways of immobilized fungal laccase during the oxidative biotransformation of a non-phenolic metabolite, 3,5-dichloroaniline (3,5-DCA) derived from dicarboximide fungicides. The maximum loading of laccase on the microporous support surfaces could reach 36.4 mg/g. The immobilized laccase on the microporous support surfaces exhibited excellent thermal stability, pH adaptability, storage stability, and reusability compared to free laccase. The ILMS assay indicated that the immobilized laccase efficiently removed studied 3,5-DCA (99-100%) in the aqueous medium, within 72 h in the presence of catechol. In this study, we identified three coupling reaction products during the removal of 3,5-DCA through an ILMS assay. Based on the identified coupling reaction products, we proposed the reaction pathway for the biotransformation of 3,5-DCA by immobilized laccase, which was shown to be potentially useful in the sustainable environmental remediation of aniline metabolite (i.e., 3,5-DCA) derived from dicarboximide fungicides. | Sarker, Aniruddha; Islam, Tofazzal; Bilal, Muhammad; Kim, Jang-Eok | Kyungpook Natl Univ, Coll Agr & Life Sci, Sch Appl Biosci, Daegu 41566, South Korea; EXIM Bank Agr Univ Bangladesh EBAUB, Dept Soil Sci, Chapainawabganj, Bangladesh; Bangabandhu Sheikh Mujibur Rahman Agr Univ, Inst Biotechnol & Genet Engn, Gazipur, Bangladesh; Huaiyin Inst Technol, Sch Life Sci & Food Engn, Huaian, Peoples R China | Sarker, Aniruddha/GYQ-6800-2022; Islam, Tofazzal/F-2563-2010; Islam, Tofazzal/C-9184-2013; Bilal, Muhammad/LXB-1628-2024 | 57211874397; 58402647300; 57316728100; 7601387161 | jekim@knu.ac.kr; | ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH | ENVIRON SCI POLLUT R | 0944-1344 | 1614-7499 | 29 | 35 | SCIE | ENVIRONMENTAL SCIENCES | 2022 | 5.8 | 24.2 | 0.63 | 2025-06-25 | 11 | 10 | Fungal laccase; Immobilization; Biotransformation; Removal efficiency; Enzyme reusability; Coupling products; Reaction pathways | TRAMETES-VERSICOLOR LACCASE; MESOPOROUS CARBON; HUMIC-ACID; REMOVAL; BIODEGRADATION; CONTAMINANTS; DEGRADATION; KINETICS | Biotransformation; Coupling products; Enzyme reusability; Fungal laccase; Immobilization; Reaction pathways; Removal efficiency | Aniline Compounds; Enzymes, Immobilized; Fungicides, Industrial; Hydrogen-Ion Concentration; Laccase; Pilot Projects; 3,5-dichloroaniline; aniline derivative; fungicide; immobilized enzyme; laccase; bioassay; biotransformation; enzyme activity; fungicide; fungus; immobilization; metabolite; pollutant removal; metabolism; pH; pilot study | English | 2022 | 2022-07 | 10.1007/s11356-022-19645-6 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Review | Concentrations, bioaccumulation, and health risk assessments of heavy metals in fishes from Nigeria's freshwater: a general overview | Heavy metals (HMs) have attracted global attention due to their toxicity, persistence, and accumulation in aquatic fish in the polluted water environment. The consumption of these fishes exposed humans to a higher risk of non-carcinogenic and carcinogenic risks. In this study, we provided a critical overview of the potential sources and concentration of HMs in Nigeria's freshwater. Furthermore, we reported their pollution level in widely eaten fish species in the country. Our findings show that effluent from anthropogenic and industrial activities is one of the major sources HMs in the country. The mean concentration of Zn (9.02 mg/L), As (7.25 mg/L), Cu (4.35 mg/L), Fe (1.77 mg/L), and Pb (1.46 mg/L) in Nigeria's freshwaters were found to be high than Nigerian Standard for Drinking Water Quality permissible limit. This study demonstrated considerable health risks associated HMs via dietary consumption of different fishes from polluted waters. Therefore, we recommended an urgent need for effective management HMs in water bodies in order to protect the lives of people living in the country. | Ajala, Oluwaseyi Aderemi; Oke, Margret Racheal; Ajibade, Temitope Fausat; Ajibade, Fidelis Odedishemi; Adelodun, Bashir; Ighalo, Joshua O.; Ajala, Margaret Opeyemi; Kumar, Pankaj; Demissie, Hailu; Ugya, Adamu Yunusa; Sulaymon, Ishaq Dimeji; Silva, Luis F. O. | Univ Ibadan, Dept Chem, Ibadan 200284, Oyo State, Nigeria; Hiroshima Univ, Grad Sch Adv Sci & Engn, Dept Appl Chem, 1-4-1 Kagamiyama, Higashihiroshima 7398527, Japan; Kwara State Polytech, Dept Agr & Bioenvironm Engn Technol, PMB 1375, Ilorin, Kwara State, Nigeria; Fed Univ Technol Akure, Dept Civil & Environm Engn, PMB 704, Akure 340110, Nigeria; Chinese Acad Sci, Inst Urban Environm, Key Lab Urban Pollutant Convers, Xiamen 361021, Peoples R China; Univ Chinese Acad Sci, Beijing 100049, Peoples R China; Org African Acad Doctors, Off Kamiti Rd,POB 25305-00100, Nairobi, Kenya; Chinese Acad Sci, Key Lab Environm Biotechnol, Res Ctr Ecoenvironm Sci, Beijing 100085, Peoples R China; Kyungpook Natl Univ, Dept Agr Civil Engn, Daegu 41566, South Korea; Univ Ilorin, Dept Agr & Biosyst Engn, PMB 1515, Ilorin 240103, Nigeria; Nnamdi Azikiwe Univ, Dept Chem Engn, PMB 5025, Awka, Nigeria; Kansas State Univ, Tim Taylor Dept Chem Engn, Manhattan, KS USA; Kwara State Univ, Dept Biosci & Biotechnol, Microbiol Unit, PMB 1530, Malete 23431, Kwara State, Nigeria; Gurukula Kangri Deemed Univ, Dept Zool & Environm Sci, Agroecol & Pollut Res Lab, Haridwar 249404, Uttarakhand, India; Arba Minch Univ, Dept Chem, Arba Minch 1000, Ethiopia; Kaduna State Univ, Dept Environm Management, Kaduna, Nigeria; Nanjing Univ Informat Sci & Technol, Jiangsu Key Lab Atmospher Environm Monitoring & P, Collaborat Innovat Ctr Atmospher Environm & Equip, Nanjing 210044, Peoples R China; Univ Costa, Dept Civil & Environm, Calle 58 55-66, Barranquilla 080002, Atlantico, Colombia | Ighalo, Joshua/D-2551-2019; Ajibade, Fidelis O./D-7893-2019; Ajibade, Fidelis/D-7893-2019; Sulaymon, Ishaq D./AAO-7610-2021; Adelodun, Bashir/O-2941-2018; Tulu, Hailu/AAL-8540-2021; Sulaymon, Ishaq/AAO-7610-2021; Silva, Luis/S-9681-2017; Kumar, Pankaj/AAF-2231-2019; Ugya, Yunusa/K-1300-2016 | 57224524356; 57923829700; 57208594522; 57190341647; 57193774482; 57202955844; 57212768586; 57281192700; 57220006581; 57196147048; 57202028433; 57192545865 | foajibade@futa.edu.ng; | ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH | ENVIRON SCI POLLUT R | 0944-1344 | 1614-7499 | 29 | 55 | SCIE | ENVIRONMENTAL SCIENCES | 2022 | 5.8 | 24.2 | 0.33 | 2025-06-25 | 8 | 13 | Fish; Freshwater; Health risks; Heavy metals; Pollution; Nigeria | STATE; RIVER; TISSUES; CONSUMPTION; POLLUTION; EXPOSURE; REGION; LEVEL; LAGOS; INDEX | Fish; Freshwater; Health risks; Heavy metals; Nigeria; Pollution | Animals; Bioaccumulation; Environmental Monitoring; Fishes; Fresh Water; Humans; Metals, Heavy; Nigeria; Risk Assessment; Water Pollutants, Chemical; Nigeria; fresh water; heavy metal; bioaccumulation; concentration (composition); freshwater; health risk; heavy metal; risk assessment; water quality; animal; bioaccumulation; environmental monitoring; fish; human; Nigeria; risk assessment; water pollutant | English | 2022 | 2022-11 | 10.1007/s11356-022-23390-1 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Foliar use of TiO2-nanoparticles for okra (Abelmoschus esculentus L. Moench) cultivation on sewage sludge-amended soils: biochemical response and heavy metal accumulation | Considering its richness in organic and inorganic mineral nutrients, the recycling of sewage sludge (SS) is highly considered as a soil supplement in agriculture. However, the fate of hazardous heavy metal accumulation in the crops cultivated in SS amended soils is always a source of concern. Since nanoparticles are widely recognized to reduce heavy metal uptake by crop plants; thus, the present experiment deals with okra (Abelmoschus esculentus L. Moench) cultivation under the combined application of SS and TiO2-nanoparticles (NPs). Triplicated pot experiments were conducted using different doses of SS and TiO2-NPs such as 0 g/kg SS (control), 50 g/kg SS, 50 g/kg SS + TiO2, 100 g/kg SS, and 100 g/kg SS + TiO2, respectively. The findings of this study indicated that among the doses of treatment combinations investigated, 100 g/kg SS + TiO2 showed a significant (p Mn > Cu > Zn > Cr > Cd using the same treatment. Bioaccumulation and health risk assessment indicated that foliar application of TiO2-NPs significantly reduced the fate of heavy metal accumulation under higher doses of SS application. Therefore, the findings of this study suggested that the combined use of SS and TiO2-NPs may be useful in ameliorating the negative consequences of heavy metal accumulation in cultivated okra crops. | Kumar, Pankaj; Alamri, Saad A. M.; Alrumman, Sulaiman A.; Eid, Ebrahem M.; Adelodun, Bashir; Goala, Madhumita; Choi, Kyung Sook; Kumar, Vinod | Gurukula Kangri Univ, Agro Ecol & Pollut Res Lab, Dept Zool & Environm Sci, Haridwar 249404, Uttarakhand, India; King Khalid Univ, Dept Biol, Coll Sci, Abha 61321, Saudi Arabia; Kafrelsheikh Univ, Dept Bot, Fac Sci, Kafr Al Sheikh 33516, Egypt; Kyungpook Natl Univ, Dept Agr Civil Engn, Daegu 41566, South Korea; Univ Ilorin, Dept Agr & Biosyst Engn, PMB 1515, Ilorin 240103, Nigeria; Affiliated Assam Univ, Nehru Coll, Pailapool, Silchar 788098, Assam, India | Adelodun, Bashir/O-2941-2018; Eid, Ebrahem/O-2723-2013; Kumar, P.Vinod/HKP-1552-2023; Kumar, Pankaj/AAF-2231-2019; Kumar, Dr. Vinod/K-9971-2016 | 57281192700; 26029065600; 55329337400; 35794350700; 57193774482; 57221943148; 54392662900; 57200152850 | drvksorwal@gkv.ac.in; | ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH | ENVIRON SCI POLLUT R | 0944-1344 | 1614-7499 | 29 | 44 | SCIE | ENVIRONMENTAL SCIENCES | 2022 | 5.8 | 24.2 | 0.5 | 2025-06-25 | 7 | 8 | Health risk assessment; Heavy metals; Nanomaterials; Sewage sludge; Target hazard quotient | TITANIUM-DIOXIDE NANOPARTICLES; WASTE-WATER TREATMENT; GROWTH; AGRICULTURE | Health risk assessment; Heavy metals; Nanomaterials; Sewage sludge; Target hazard quotient | Abelmoschus; Cadmium; Catalase; Chlorophyll; Crops, Agricultural; Metals, Heavy; Minerals; Nanoparticles; Sewage; Soil; Superoxide Dismutase; Titanium; cadmium; catalase; chlorophyll; heavy metal; mineral; nanoparticle; superoxide dismutase; titanium; titanium dioxide; angiosperm; bioaccumulation; biochemistry; cultivation; foliage; health risk; heavy metal; nanomaterial; nanoparticle; risk assessment; sewage treatment; soil amendment; Abelmoschus; crop; sewage; soil | English | 2022 | 2022-09 | 10.1007/s11356-022-20526-1 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Correction | Foliar use of TiO2-nanoparticles for okra (Abelmoschus esculentus L. Moench) cultivation on sewage sludge-amended soils: biochemical response and heavy metal accumulation (vol 29, pg 66507, 2022) | Kumar, Pankaj; Alamri, Saad A. M.; Alrumman, Sulaiman A.; Eid, Ebrahem M.; Adelodun, Bashir; Goala, Madhumita; Choi, Kyung Sook; Kumar, Vinod | Gurukula Kangri, Agro Ecol & Pollut Res Lab, Dept Zool & Environm Sci, Haridwar 249404, Uttarakhand, India; King Khalid Univ, Coll Sci, Biol Dept, Abha 61321, Saudi Arabia; Kafrelsheikh Univ, Fac Sci, Bot Dept, Kafr Al Sheikh 33516, Egypt; Kyungpook Natl Univ, Dept Agr Civil Engn, Daegu 41566, South Korea; Univ Ilorin, Dept Agr & Biosyst Engn, PMB 1515, Ilorin 240003, Nigeria; Affiliated Assam Univ, Nehru Coll, Silchar 788098, Assam, India | Adelodun, Bashir/O-2941-2018; Alamri, Saad/AGM-5459-2022; Kumar, Pankaj/AAB-4153-2019; Kumar, P.Vinod/HKP-1552-2023; Eid, Ebrahem/O-2723-2013 | 57281192700; 26029065600; 55329337400; 35794350700; 57193774482; 57221943148; 54392662900; 57200152850 | drvksorwal@gkv.ac.in; | ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH | ENVIRON SCI POLLUT R | 0944-1344 | 1614-7499 | 29 | 54 | SCIE | ENVIRONMENTAL SCIENCES | 2022 | 5.8 | 24.2 | 0 | 2025-06-25 | 0 | 0 | erratum | English | 2022 | 2022-11 | 10.1007/s11356-022-23655-9 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||||
| ○ | ○ | Review | Heavy metals contamination and associated health risks in food webs-a review focuses on food safety and environmental sustainability in Bangladesh | Heavy metals occur naturally in very small amounts in living organisms, but exposure to their higher concentrations is hazardous. Heavy metals at hazardous levels are commonly found in foodstuffs of Bangladesh, mainly due to the lack of safety guidelines and poor management of industrial effluents. Several lines of evidence suggest that the level of heavy metals in foodstuffs of Bangladesh is higher than the acceptable limits set by World Health Organization/Food and Agriculture Organization. Literature survey revealed that the sources and transport pathways of heavy metals in the ecosystem and the abundance of heavy metals in the food products of Bangladesh are potential threats to food safety. However, an extensive assessment of the toxicity of heavy metals in food webs is lacking. Although widespread heavy metal contamination in various foodstuffs and environmental matrices have been summarized in some reports, a critical evaluation regarding multi-trophic transfer and the health risk of heavy metal exposure through food chain toxicity in Bangladesh has not been performed. This systematic review critically discussed heavy metal contamination, exposure toxicity, research gaps, existing legislation, and sustainable remediation strategies to enhance Bangladesh's food safety. In particular, this study for the first time explored the potential multi-trophic transfer of heavy metals via food webs in Bangladesh. Furthermore, we recommended a conceptual policy framework to combat heavy metal contaminations in Bangladesh. | Sarker, Aniruddha; Kim, Jang-Eok; Islam, Abu Reza Md Towfiqul; Bilal, Muhammad; Rakib, Md Refat Jahan; Nandi, Rakhi; Rahman, Mohammed M.; Islam, Tofazzal | Kyungpook Natl Univ, Coll Agr & Life Sci, Sch Appl Biosci, Daegu 41566, South Korea; Begum Rokeya Univ, Dept Disaster Management, Rangpur 5400, Bangladesh; Huaiyin Inst Technol, Sch Life Sci & Food Engn, Huaian, Peoples R China; Noakhali Sci & Technol Univ, Fac Sci, Dept Fisheries & Marine Sci, Noakhali, Bangladesh; Bangabandhu Sheikh Mujibur Rahman Agr Univ, Inst Biotechnol & Genet Engn IBGE, Gazipur, Bangladesh; EXIM Bank Agr Univ Bangladesh EBAUB, Dept Soil Sci, Chapainawabganj, Bangladesh; Bangladesh Acad Rural Dev BARD, Kotbari, Cumilla, Bangladesh; King Abdulaziz Univ, Dept Chem, Jeddah 21589, Saudi Arabia | Sarker, Aniruddha/GYQ-6800-2022; Rahman, Mostafizur/X-7420-2019; Islam, Abu Reza Md. Towfiqul/O-8554-2019; Islam, Tofazzal/C-9184-2013; Islam, Tofazzal/F-2563-2010 | 57211874397; 7601387161; 57218543677; 59174683900; 57221225845; 57216177596; 56962749100; 58402647300 | tofazzalislam@bsmrau.edu.bd; | ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH | ENVIRON SCI POLLUT R | 0944-1344 | 1614-7499 | 29 | 3 | SCIE | ENVIRONMENTAL SCIENCES | 2022 | 5.8 | 24.2 | 3.39 | 2025-06-25 | 111 | 135 | Heavy metals; Food safety; Risk assessment; Exposure toxicity; Policy framework | TUBE WELL WATER; TRACE-ELEMENTS; ARSENIC CONTAMINATION; SEASONAL-VARIATION; RIVER ESTUARY; VEGETABLES; FISH; POLLUTION; SEDIMENT; EXPOSURE | Exposure toxicity; Food safety; Heavy metals; Policy framework; Risk assessment | Bangladesh; Ecosystem; Environmental Monitoring; Food Chain; Food Contamination; Food Safety; Metals, Heavy; Risk Assessment; Bangladesh; World; heavy metal; ecosystem; environmental conditions; food chain; food safety; food web; health risk; heavy metal; remediation; sustainability; toxicity; Bangladesh; ecosystem; environmental monitoring; food chain; food contamination; food safety; risk assessment | English | 2022 | 2022-01 | 10.1007/s11356-021-17153-7 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Review | Addressing Blood-Brain Barrier Impairment in Alzheimer's Disease | The blood-brain barrier (BBB) plays a vital role in maintaining the specialized microenvironment of the brain tissue. It facilitates communication while separating the peripheral circulation system from the brain parenchyma. However, normal aging and neurodegenerative diseases can alter and damage the physiological properties of the BBB. In this review, we first briefly present the essential pathways maintaining and regulating BBB integrity, and further review the mechanisms of BBB breakdown associated with normal aging and peripheral inflammation-causing neurodegeneration and cognitive impairments. We also discuss how BBB disruption can cause or contribute to Alzheimer's disease (AD), the most common form of dementia and a devastating neurological disorder. Next, we document overlaps between AD and vascular dementia (VaD) and briefly sum up the techniques for identifying biomarkers linked to BBB deterioration. Finally, we conclude that BBB breakdown could be used as a biomarker to help diagnose cognitive impairment associated with normal aging and neurodegenerative diseases such as AD. | Sharma, Chanchal; Woo, Hanwoong; Kim, Sang Ryong | Kyungpook Natl Univ, Sch Life Sci, Daegu 41566, South Korea; Kyungpook Natl Univ, BK21 FOUR KNU Creat BioRes Grp, Daegu 41566, South Korea; Kyungpook Natl Univ, Brain Sci & Engn Inst, Daegu 41404, South Korea | 57193577728; 57561258900; 56486163800 | chanchalmrt@gmail.com;hwwoo@knu.ac.kr;srk75@knu.ac.kr; | BIOMEDICINES | BIOMEDICINES | 2227-9059 | 10 | 4 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY;MEDICINE, RESEARCH & EXPERIMENTAL;PHARMACOLOGY & PHARMACY | 2022 | 4.7 | 24.3 | 1.84 | 2025-06-25 | 40 | 41 | blood-brain barrier; aging; peripheral inflammation; Alzheimer's disease | CEREBRAL AMYLOID ANGIOPATHY; A-BETA; CEREBROSPINAL-FLUID; P-GLYCOPROTEIN; MOUSE MODEL; MULTIPLE-SCLEROSIS; TIGHT JUNCTIONS; NEUROVASCULAR PATHWAYS; CORD BARRIER; IN-VIVO | aging; Alzheimer’s disease; blood–brain barrier; peripheral inflammation | English | 2022 | 2022-04 | 10.3390/biomedicines10040742 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||||
| ○ | ○ | Article | Alteration of Gut Immunity and Microbiome in Mixed Granulocytic Asthma | Growing evidence suggests that there is an essential link between the gut and lungs. Asthma is a common chronic inflammatory disease and is considered a heterogeneous disease. While it has been documented that eosinophilic asthma affects gut immunity and the microbiome, the effect of other types of asthma on the gut environment has not been examined. In this study, we utilized an OVA/poly I:C-induced mixed granulocytic asthma model and found increased Tregs without significant changes in other inflammatory cells in the colon. Interestingly, an altered gut microbiome has been observed in a mixed granulocytic asthma model. We observed an increase in the relative abundance of the Faecalibaculum genus and Erysipelotrichaceae family, with a concomitant decrease in the relative abundance of the genera Candidatus arthromitus and Streptococcus. The altered gut microbiome leads to changes in the abundance of genes associated with microbial metabolism, such as glycolysis. We found that mixed granulocytic asthma mainly affects the gut microbial composition and metabolism, which may have important implications in the severity and development of asthma and gut immune homeostasis. This suggests that altered gut microbial metabolism may be a potential therapeutic target for patients with mixed granulocytic asthma. | Gu, Bon-Hee; Rim, Chae-Yun; Lee, Sangjin; Kim, Tae-Yong; Joo, Sang-Seok; Lee, Sang-Jin; Park, Han-Ki; Kim, Myunghoo | Pusan Natl Univ, Life & Ind Convergence Res Inst, Miryang 50463, South Korea; Pusan Natl Univ, Coll Nat Resources & Life Sci, Dept Anim Sci, Miryang 50463, South Korea; Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu 41944, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Dept Internal Med, Sch Med,Div Allergy & Clin Immunol, Daegu 41404, South Korea | Park, Han-Ki/AAY-3102-2020 | 26537340600; 57222586213; 57209989226; 57222744974; 57215860725; 57218664064; 36611749600 | haan33@gmail.com;mhkim18@pusan.ac.kr; | BIOMEDICINES | BIOMEDICINES | 2227-9059 | 10 | 11 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY;MEDICINE, RESEARCH & EXPERIMENTAL;PHARMACOLOGY & PHARMACY | 2022 | 4.7 | 24.3 | 0.69 | 2025-06-25 | 7 | 7 | mixed granulocytic asthma; gut microbiota; intestinal immune cells; microbial metabolism | INFLAMMATORY-BOWEL-DISEASE; INTESTINAL MICROBIOTA; MICE; PREVALENCE; METABOLISM; NEUTROPHIL; BACTERIA; CELLS; GAMMA | gut microbiota; intestinal immune cells; microbial metabolism; mixed granulocytic asthma | English | 2022 | 2022-11 | 10.3390/biomedicines10112946 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Application of Bio-Active Elastin-like Polypeptide on Regulation of Human Mesenchymal Stem Cell Behavior | Regenerative medicine using stem cells offers promising strategies for treating a variety of degenerative diseases. Regulation of stem cell behavior and rejuvenate senescence are required for stem cells to be clinically effective. The extracellular matrix (ECM) components have a significant impact on the stem cell's function and fate mimicking the local environment to maintain cells or generate a distinct phenotype. Here, human elastin-like polypeptide-based ECM-mimic biopolymer was designed by incorporating various cell-adhesion ligands, such as RGD and YIGSR. The significant effects of bioactive fusion ELPs named R-ELP, Y-ELP, and RY-ELP were analyzed for human bone-marrow-derived stem cell adhesion, proliferation, maintenance of stemness properties, and differentiation. Multivalent presentation of variable cell-adhesive ligands on RY-ELP polymers indeed promote efficient cell attachment and proliferation of human fibroblast cells dose-dependently. Similarly, surface modified with RY-ELP promoted strong mesenchymal stem cell (MSCs) attachment with greater focal adhesion (FA) complex formation at 6 h post-incubation. The rate of cell proliferation, migration, population doubling time, and collagen I deposition were significantly enhanced in the presence of RY-ELP compared with other fusion ELPs. Together, the expression of multipotent markers and differentiation capacity of MSCs remained unaffected, clearly demonstrating that stemness properties of MSCs were well preserved when cultured on a RY-ELP-modified surface. Hence, bioactive RY-ELP offers an anchorage support system and effectively induces stimulatory response to support stem cell proliferation. | Sarangthem, Vijaya; Sharma, Harshita; Mendiratta, Mohini; Sahoo, Ranjit Kumar; Park, Rang-Woon; Kumar, Lalit; Singh, Thoudam Debraj; Mohanty, Sujata | Kyungpook Natl Univ, Sch Med, Cell & Matrix Res Inst, Dept Biochem & Cell Biol, Daegu 41944, South Korea; All India Inst Med Sci, Dept Pathol, New Delhi 110029, India; All India Inst Med Sci, DBT Ctr Excellence Stem Cell Res, Stem Cell Facil, New Delhi 110029, India; All India Inst Med Sci, Dept Med Oncol, New Delhi 110029, India; All India Inst Med Sci, Dept Med Oncol Lab, New Delhi 110029, India | Kumar, Lalit/JFK-9602-2023; sharma, Harshita/HZL-6535-2023; Sarangthem, Vijaya/AAX-7421-2020 | 56001741200; 57220821982; 57711511400; 57211415387; 7401895636; 57651428700; 55190689800; 57203030715 | devi1703@gmail.com;sharshita558@gmail.com;mohinimendiratta@gmail.com;drranjitmd@gmail.com;nwpark@knu.ac.kr;lalitaiims@yahoo.com;debraj.thoudam@gmail.com;drmohantysujata@gmail.com; | BIOMEDICINES | BIOMEDICINES | 2227-9059 | 10 | 5 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY;MEDICINE, RESEARCH & EXPERIMENTAL;PHARMACOLOGY & PHARMACY | 2022 | 4.7 | 24.3 | 0.3 | 2025-06-25 | 2 | 3 | elastin-like polypeptide; biopolymer; integrin; laminin; extracellular matrix; stem cells; cell differentiation | EXTRACELLULAR-MATRIX; FUSION PROTEINS; STROMAL CELLS; DELIVERY; FIBROBLASTS; NANOPARTICLES; EXPRESSION; PEPTIDES; BIOLOGY | biopolymer; cell differentiation; elastin-like polypeptide; extracellular matrix; integrin; laminin; stem cells | English | 2022 | 2022-05 | 10.3390/biomedicines10051151 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Review | Axonal Regeneration: Underlying Molecular Mechanisms and Potential Therapeutic Targets | Axons in the peripheral nervous system have the ability to repair themselves after damage, whereas axons in the central nervous system are unable to do so. A common and important characteristic of damage to the spinal cord, brain, and peripheral nerves is the disruption of axonal regrowth. Interestingly, intrinsic growth factors play a significant role in the axonal regeneration of injured nerves. Various factors such as proteomic profile, microtubule stability, ribosomal location, and signalling pathways mark a line between the central and peripheral axons' capacity for self-renewal. Unfortunately, glial scar development, myelin-associated inhibitor molecules, lack of neurotrophic factors, and inflammatory reactions are among the factors that restrict axonal regeneration. Molecular pathways such as cAMP, MAPK, JAK/STAT, ATF3/CREB, BMP/SMAD, AKT/mTORC1/p70S6K, PI3K/AKT, GSK-3 beta/CLASP, BDNF/Trk, Ras/ERK, integrin/FAK, RhoA/ROCK/LIMK, and POSTN/integrin are activated after nerve injury and are considered significant players in axonal regeneration. In addition to the aforementioned pathways, growth factors, microRNAs, and astrocytes are also commendable participants in regeneration. In this review, we discuss the detailed mechanism of each pathway along with key players that can be potentially valuable targets to help achieve quick axonal healing. We also identify the prospective targets that could help close knowledge gaps in the molecular pathways underlying regeneration and shed light on the creation of more powerful strategies to encourage axonal regeneration after nervous system injury. | Akram, Rabia; Anwar, Haseeb; Javed, Muhammad Shahid; Rasul, Azhar; Imran, Ali; Malik, Shoaib Ahmad; Raza, Chand; Khan, Ikram Ullah; Sajid, Faiqa; Iman, Tehreem; Sun, Tao; Han, Hyung Soo; Hussain, Ghulam | Govt Coll Univ, Fac Life Sci, Dept Physiol, Neurochem Biol & Genet Lab NGL, Faisalabad 38000, Pakistan; Sargodha Med Coll, Dept Physiol, Sargodha 40100, Pakistan; Govt Coll Univ, Fac Life Sci, Dept Zool, Faisalabad 38000, Pakistan; Govt Coll Univ, Dept Food Sci, Faisalabad 38000, Pakistan; Sargodha Med Coll, Dept Biochem, Sargodha 40100, Pakistan; Govt Coll Univ, Fac Chem & Life Sci, Dept Zool, Lahore 54000, Pakistan; Govt Coll Univ, Fac Pharmaceut Sci, Dept Pharmaceut, Faisalabad 38000, Pakistan; Huaqiao Univ, Ctr Precis Med, Sch Med, Xiamen 361021, Peoples R China; Huaqiao Univ, Sch Biomed Sci, Xiamen 361021, Peoples R China; Kyungpook Natl Univ, Clin Omics Inst, Sch Med, Dept Physiol, Daegu 41944, South Korea | SUn, Tao/G-6474-2010; HUSSAIN, Ghulam/S-7609-2016; Akram, Rabia/KIE-7810-2024; Raza, Chand/AAE-3924-2021; KHAN, Ikram/F-2657-2013; HUSSAIN, Ghulam/LLM-1486-2024; Rasul, Azhar/AAF-5253-2021; Imran, Ali/J-1316-2019 | 57211939237; 36149275200; 24072996300; 40661679700; 57203170148; 24773658100; 57208259820; 57194341390; 57220633559; 57653501900; 55053078500; 7401969388; 57221106374 | gh_azer@hotmail.com;ghulamhussain@gcuf.edu.pk; | BIOMEDICINES | BIOMEDICINES | 2227-9059 | 10 | 12 | SCIE | BIOCHEMISTRY & MOLECULAR BIOLOGY;MEDICINE, RESEARCH & EXPERIMENTAL;PHARMACOLOGY & PHARMACY | 2022 | 4.7 | 24.3 | 2.39 | 2025-06-25 | 58 | 54 | axonal regeneration; nerve injury; regeneration-associated genes; neurotrophic factors; cyclic adenosine monophosphate; microRNAs | PERIPHERAL-NERVE REGENERATION; PROMOTES NEURITE OUTGROWTH; RETINAL GANGLION-CELLS; SPINAL-CORD-INJURY; SIGNALING PATHWAY; TENASCIN-C; EXTRACELLULAR-MATRIX; RHOA/RHO-KINASE; GROWTH-CONTROL; RAT MODEL | axonal regeneration; cyclic adenosine monophosphate; microRNAs; nerve injury; neurotrophic factors; regeneration-associated genes | English | 2022 | 2022-12 | 10.3390/biomedicines10123186 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
페이지 이동: