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| WoS | SCOPUS | Document Type | Document Title | Abstract | Authors | Affiliation | ResearcherID (WoS) | AuthorsID (SCOPUS) | Author Email(s) | Journal Name | JCR Abbreviation | ISSN | eISSN | Volume | Issue | WoS Edition | WoS Category | JCR Year | IF | JCR (%) | FWCI | FWCI Update Date | WoS Citation | SCOPUS Citation | Keywords (WoS) | KeywordsPlus (WoS) | Keywords (SCOPUS) | KeywordsPlus (SCOPUS) | Language | Publication Stage | Publication Year | Publication Date | DOI | JCR Link | DOI Link | WOS Link | SCOPUS Link |
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| ○ | ○ | Article | Initial Experience of Articulating Laparoscopic Instruments for Benign Gynecologic Disease: A Single-Arm Multicenter Prospective Study (Korean Gynecologic Oncology Group 4002) | Laparoscopic surgery has evolved with technological advances in many aspects and increasing demand for its benefits in cosmetics, fast recovery, reduced complication rates and pain. However, it still possesses drawbacks such as limited surgical movement due to the nature of rigid laparoscopic instruments. In order to overcome such limitations, several laparoscopic jointed instruments have been developed. In this prospective multicenter, single-arm cohort study, we investigated the short-term safety and feasibility of the new articulating laparoscopic instruments in benign gynecologic surgery. A total of 113 patients who were diagnosed with benign gynecologic adnexal diseases underwent laparoscopic surgery with articulating laparoscopic instruments. Surgical outcomes, including intra/postoperative complication rates, operation time and estimated blood loss, as well as surgeon's subjective evaluation of the usage of the instruments, were evaluated. The results demonstrated that the articulating laparoscopic instruments had comparable usability and produced similar surgical outcomes to conventional laparoscopic surgery. The objective parameters, such as the operative time and complication rates, as well as the subjective parameters, such as the surgeon's own evaluation of the surgical instruments' usability, demonstrated potential benefits of the instruments in benign gynecological diseases. Overall, the study demonstrated that the use of this novel articulating device is feasible in gynecologic laparoscopic surgery. | Noh, Joseph J.; Kim, Kidong; Kim, Tae-Joong; Kim, Taehun; Lee, Keun Ho; Hwang, Jong Ha; Hong, Dae Gy; Kim, Min Kyu; Lee, Banghyun; Chang, Ha Kyun; Chun, Kyoung Chul | Sungkyunkwan Univ, Gynecol Canc Ctr, Samsung Med Ctr, Dept Obstet & Gynecol,Sch Med, Seoul 06351, South Korea; Seoul Natl Univ, Dept Obstet & Gynecol, Bundang Hosp, Coll Med, Seongnam 13620, South Korea; Seoul Natl Univ, Seoul Metropolitan Govt, Boramae Med Ctr, Dept Obstet & Gynecol, Seoul 07061, South Korea; Catholic Univ Korea, Seoul St Marys Hosp, Dept Obstet & Gynecol, Seoul 14662, South Korea; Catholic Kwandong Univ, Int St Marys Hosp, Dept Obstet & Gynecol, Coll Med, Incheon 22711, South Korea; Kyungpook Natl Univ, Sch Med, Dept Obstet & Gynecol, Daegu 41566, South Korea; Sungkyunkwan Univ, Sch Med, Samsung Changwon Hosp, Div Gynecol Oncol,Dept Obstet & Gynecol, Chang Won 51353, South Korea; Inha Univ Hosp, Inha Univ, Coll Med, Dept Obstet & Gynecol, 27 Inhang ro, Incheon 22332, South Korea; Korea Univ, Ansan Hosp, Dept Obstet & Gynecol, Sch Med, Ansan 15355, South Korea; InJe Univ, Ilsan Paik Hosp, Dept Obstet & Gynecol, Coll Med, Goyang 10380, South Korea | kim, nayoung/IWV-4038-2023; Kim, Min/ACN-6827-2022 | 57209105352; 35740868200; 29767612300; 56575227700; 57203464464; 7403895581; 26656670100; 56053945200; 56190573400; 57193611268; 57188623448 | joseph.noh@samsung.com;kidong.kim.md@gmail.com;tj28.kim@samsung.com;coolluck1979@gmail.com;hohoho@catholic.ac.kr;jh36640@hanmail.ne;chssa0220@hanmail.net;banghyun.lee@gmail.com;coolblue23@naver.com;kcchun@paik.ac.kr; | JOURNAL OF PERSONALIZED MEDICINE | J PERS MED | 2075-4426 | 13 | 10 | SCIE | HEALTH CARE SCIENCES & SERVICES;MEDICINE, GENERAL & INTERNAL | 2023 | 3 | 17.8 | 0.23 | 2025-06-25 | 2 | 1 | surgery; articulating laparoscopy; surgical instruments; minimally invasive surgical procedures; gynecology | COST-EFFECTIVENESS; ROBOTIC SURGERY; HYSTERECTOMY | articulating laparoscopy; gynecology; minimally invasive surgical procedures; surgery; surgical instruments | hemoglobin; adhesiolysis; adnexa disease; adnexal surgery; adult; Article; bleeding; blood transfusion; cancer surgery; clinical outcome; cohort analysis; computer assisted tomography; cystectomy; demographics; echography; endometriosis; endotracheal intubation; experience; feasibility study; female; general anesthesia; gynecologic disease; gynecologic surgery; human; hydrosalpinx; hysterectomy; imaging; laparoscopic surgery; laparoscopy; lithotomy; major clinical study; middle aged; minimally invasive procedure; multicenter study; myomectomy; nuclear magnetic resonance imaging; operation duration; outcome assessment; ovarian cystectomy; ovariectomy; ovary cyst; peroperative complication; postoperative complication; prospective study; questionnaire; robot assisted surgery; sacrocolpopexy; salpingectomy; salpingitis; salpingooophorectomy; surgical technique; training | English | 2023 | 2023-10 | 10.3390/jpm13101433 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Injecting cognitive intelligence into beyond-5G networks: A MAC layer perspective | The rapid rise of heterogeneous data traffic exposes the shortcomings of fifth-generation (5G) technology, which was initially designed to form self-organizing and self-sustaining networks to facilitate the adoption of the Internet-of-Everything (IoE). This study presents the applications and service requirements of future communication networks. This study details flexible design agreements of the Medium Access Control (MAC) layer of Beyond-5G (B5G) from the current 3rd Generation Partnership (3GPP) study and highlights the current open research issues and challenges which are yet to be optimized. To ensure that the network is self-sustaining and self -organized for B5G paradigm, an intelligent network design is required. Artificial Intelligence (AI) is revolutionizing every aspect of life, therefore, this article provides an overview of how AI plays an important role in improving future-generation communication by solving MAC-related issues. | Nauman, Ali; Jamshed, Muhammad Ali; Ahmad, Yazdan; Saad, Malik; Bilal, Muhammad; Shanmuganathan, Vimal; Kim, Sung Won | Yeungnam Univ, Dept Informat & Commun Engn, Gyeongsan si, Gyongsan, Gyeongsangbuk D, South Korea; Univ Glasgow, James Watt Sch Engn, Glasgow, Scotland; Kyungpook Natl Univ, Sch Comp Sci & Engn, Daegu, South Korea; Hankuk Univ Foreign Studies, Dept Comp Engn, Yongin, Gyeonggi Do, South Korea; Ramco Inst Technol, Dept Artificial Intelligence & Data Sci, Rajapalayam, Tamilnadu, India | Jamshed, Muhammad Ali/AAB-3421-2019; SHANMUGANATHAN, VIMAL/E-9551-2016; Bilal, Muhammad/F-5225-2019; Nauman, Ali/KJD-5577-2024; Saad, Malik/ABF-9433-2021 | 57210321511; 57189063536; 57209802975; 57220715290; 56562681700; 57150956300; 57202048340 | anauman@ynu.ac.kr;muhammadali.jamshed@glasgow.ac.uk;yazdan@ynu.ac.kr;saad@knu.ac.kr;vimal@ritrjpm.ac.in;swon@yu.ac.kr; | COMPUTERS & ELECTRICAL ENGINEERING | COMPUT ELECTR ENG | 0045-7906 | 1879-0755 | 108 | SCIE | COMPUTER SCIENCE, HARDWARE & ARCHITECTURE;COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS;ENGINEERING, ELECTRICAL & ELECTRONIC | 2023 | 4 | 17.8 | 0.63 | 2025-06-25 | 5 | 5 | New radio (NR); Beyond 5G (B5G); Artificial intelligence (AI); Medium access control (MAC) layer | CELLULAR V2X; 5G; DESIGN; URLLC; COMMUNICATION | Artificial intelligence (AI); Beyond 5G (B5G); Medium access control (MAC) layer; New radio (NR) | 5G mobile communication systems; Internet of Everything; Queueing networks; 'current; Application requirements; Artificial intelligence; Beyond 5g; Cognitive intelligence; Data traffic; Heterogeneous data; Medium access control layer; New radio; Self-organising; Artificial intelligence | English | 2023 | 2023-05 | 10.1016/j.compeleceng.2023.108717 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Letter | Letter to the Editor: Consideration of Neuroimmunological Diseases in Assessments of COVID-19 Vaccination Rates Among Patients With Chronic Medical Conditions | Kim, Sohyeon; Eun, Mi-Yeon; Seok, Hung Youl | Keimyung Univ, Dongsan Hosp, Dept Neurol, Sch Med, Daegu, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Sch Med, Dept Neurol, Daegu, South Korea; Keimyung Univ, Dept Neurol, Dongsan Hosp, Sch Med, 1035 Dalgubeol Daero, Daegu 42601, South Korea | Eun, Mi-Yeon/AAV-2877-2021; Seok, Hung Youl/HZI-4365-2023 | 57214724357; 36463396500; 24472118000 | shy2354@gmail.com; | JOURNAL OF KOREAN MEDICAL SCIENCE | J KOREAN MED SCI | 1011-8934 | 1598-6357 | 38 | 3 | SCIE | MEDICINE, GENERAL & INTERNAL | 2023 | 3 | 17.8 | 0.59 | 2025-06-25 | 1 | 1 | Chronic Disease; COVID-19; COVID-19 Vaccines; Cross-Sectional Studies; Humans; Vaccination; chronic disease; cross-sectional study; human; prevention and control; vaccination | English | 2023 | 2023-01-16 | 10.3346/jkms.2023.38.e35 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||||
| ○ | ○ | Article | Management of Steroid-Induced Glaucoma in a Patient with Pyoderma Gangrenosum | Pyoderma gangrenosum (PG) is an uncommon inflammatory skin disorder typically presenting as painful skin ulcers, which may also exhibit extracutaneous findings. PG can occur at the site of trauma or surgery, which is known as the pathergic phenomenon. A 36-year-old man developed bilateral steroid-induced glaucoma after prolonged systemic immunosuppressive treatment for cutaneous pyoderma gangrenosum. After successful Ahmed glaucoma valve implantation surgery with donor scleral patch graft in the right eye, the same surgery failed repeatedly in the left eye and complicated with the prolonged conjunctival necrosis and the exposure of the donor scleral patch graft. Under the impression of ocular involvement of PG, microinvasive glaucoma surgery (MIGS) with XEN (R) Gel Stent was performed in the left eye; the conjunctival bleb was successfully formed without conjunctival necrosis, and intraocular pressure was well maintained. Ophthalmic surgery can be complicated in patients with PG, and the surgical option should be selected prudently to minimize surgical trauma. MIGS, as a minimally invasive surgical technique, could offer an advantage for patients with PG. | Byun, Ji Yeon; Kang, Yong Koo; Jang, Yong Hyun; Kim, Young Kook; Kim, Dai Woo | Ewha Womans Univ, Dept Dermatol, Coll Med, Seoul 07804, South Korea; Kyungpook Natl Univ, Sch Med, Dept Ophthalmol, Daegu 41944, South Korea; Kyungpook Natl Univ, Sch Med, Dept Dermatol, Daegu 41944, South Korea; Seoul Natl Univ, Dept Ophthalmol, Coll Med, Seoul 03080, South Korea | KANG, YONG KOO/IVH-8723-2023; Kim, Young-Kook/AAE-8306-2020 | 15724462400; 57204703736; 57016046400; 55908959500; 57095192800 | proector97@gmail.com; | JOURNAL OF CLINICAL MEDICINE | J CLIN MED | 2077-0383 | 12 | 8 | SCIE | MEDICINE, GENERAL & INTERNAL | 2023 | 3 | 17.8 | 0 | 2025-06-25 | 0 | 0 | pyoderma gangrenosum; glaucoma; Ahmed glaucoma valve; microinvasive glaucoma surgery | SURGICAL INTERVENTION; STENT | Ahmed glaucoma valve; glaucoma; microinvasive glaucoma surgery; pyoderma gangrenosum | brimonidine; cyclophosphamide; dorzolamide plus timolol; latanoprost; mitomycin; mycophenolate mofetil; prednisolone; steroid; adult; Article; best corrected visual acuity; case report; clinical article; conjunctiva; conjunctiva disease; conjunctival necrosis; conservative treatment; cup-to-disc ratio; Delphi study; erythema; eye examination; eye pain; eye redness; eye surgery; follow up; glaucoma; glaucoma surgery; histopathology; human; human tissue; immunosuppressive treatment; intraocular pressure; limb; male; managed care; microinvasive glaucoma surgery; necrosis; ophthalmoscopy; optical coherence tomography; organ donor; perimetry; pyoderma gangrenosum; retinal nerve fiber layer; sclera; scleral patch graft; skin defect; skin ulcer; slit lamp microscopy; steroid induced glaucoma; surgical injury; tissue culture; tissue necrosis; trabeculectomy; treatment failure; trunk; ulcerative patch; visual acuity; visual field | English | 2023 | 2023-04 | 10.3390/jcm12082930 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Medial Arterial Calcification and the Risk of Amputation of Diabetic Foot Ulcer in Patients With Diabetic Kidney Disease | We assessed the risk factors for major amputation of diabetic foot ulcers (DFUs) in patients with diabetic kidney disease (DKD) stages 3b-5. For DFU assessment, in addition to DFU location and presence of infection, ischemia, and neuropathy, vascular calcification was assessed using the medial arterial calcification (MAC) score. Of 210 patients, 26 (12.4%) underwent major amputations. Only the location and extension of DFU, represented by Texas grade differed between the minor and major amputation groups. However, after adjusting for covariates, ulcer location of mid-or hindfoot (vs. forefoot, odds ratio [OR] = 3.27), Texas grades 2 or 3 (vs. grade 0, OR = 5.78), and severe MAC (vs. no MAC, OR = 4.46) was an independent risk factor for major amputation (all P < 0.05). The current use of antiplatelets was a possible protective factor for major amputations (OR = 0.37, P = 0.055). In conclusion, DFU with severe MAC is associated with major amputation in patients with DKD. | So, Joon Myeong; Park, Ji Ho; Kim, Jin Gyeong; Park, Il Rae; Ha, Eun Yeong; Chung, Seung Min; Moon, Jun Sung; Park, Chul Hyun; Yun, Woo-Sung; Kim, Tae-Gon; Kim, Woong; Yoon, Ji Sung; Won, Kyu Chang; Lee, Hyoung Woo | Yeungnam Univ, Coll Med, Daegu, South Korea; Yeungnam Univ, Dept Internal Med, Div Endocrinol & Metab, Coll Med, 170 Hyeonchung Ro, Daegu 42415, South Korea; Yeungnam Univ, Dept Orthoped Surg, Coll Med, Daegu, South Korea; Kyungpook Natl Univ, Dept Surg, Sch Med, Daegu, South Korea; Yeungnam Univ, Dept Plast Surg, Coll Med, Daegu, South Korea; Yeungnam Univ, Dept Internal Med, Div Cardiol, Coll Med, Daegu, South Korea | ; Chung, Seung Min/HNC-5825-2023; Kim, Tae-Gon/ABH-4464-2020; park, chul-hyun/C-7298-2009 | 58306968000; 58306766100; 58305939200; 57189328461; 57216645230; 57192252291; 55261990400; 55598051400; 35070717000; 55696492600; 7405810284; 55460494800; 57206373141; 59105261100 | smchung@ynu.ac.kr;mjs7912@yu.ac.kr; | JOURNAL OF KOREAN MEDICAL SCIENCE | J KOREAN MED SCI | 1011-8934 | 1598-6357 | 38 | 21 | SCIE | MEDICINE, GENERAL & INTERNAL | 2023 | 3 | 17.8 | 1.28 | 2025-06-25 | 5 | 5 | Amputation; Diabetic Foot Ulcer; Diabetic Kidney Disease; Medial Arterial Calcification | COMPLICATIONS; ASSOCIATION | Amputation; Diabetic Foot Ulcer; Diabetic Kidney Disease; Medial Arterial Calcification | Amputation, Surgical; Diabetes Mellitus; Diabetic Foot; Diabetic Nephropathies; Humans; Retrospective Studies; Risk Factors; amputation; complication; diabetes mellitus; diabetic foot; diabetic nephropathy; human; retrospective study; risk factor | English | 2023 | 2023-04-24 | 10.3346/jkms.2023.38.e160 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Mesenchymal Stem Cell Transplantation Ameliorates Ara-C-Induced Motor Deficits in a Mouse Model of Cerebellar Ataxia | This study investigated the therapeutic effects of transplanting human mesenchymal stem cells (hMSCs) into wild-type mice that were intraperitoneally administered cytosine arabinoside (Ara-C) to develop cerebellar ataxia (CA) during the first three postnatal days. hMSCs were intrathecally injected into 10-week-old mice once or thrice at 4-week intervals. Compared to the nontreated mice, the hMSC-treated mice showed improved motor and balance coordination, as measured using the rotarod, open-field, and ataxic scoring assessments, and increased protein levels in Purkinje and cerebellar granule cells, as measured using calbindin and NeuN protein markers. Multiple hMSC injections preserved Ara-C-induced cerebellar neuronal loss and improved cerebellar weight. Furthermore, the hMSC implantation significantly elevated the levels of neurotrophic factors, including brain-derived and glial cell line-derived neurotrophic factors, and suppressed TNF-alpha-, IL-1 beta-, and iNOS-mediated proinflammatory responses. Collectively, our results demonstrate that hMSCs exhibit therapeutic potential for Ara-C-induced CA by protecting neurons through the stimulation of neurotrophic factors and inhibition of cerebellar inflammatory responses, which can improve motor behavior and alleviate ataxia-related neuropathology. In summary, this study suggests that hMSC administration, particularly multiple treatments, can effectively treat ataxia-related symptoms with cerebellar toxicity. | Park, Narae; Sharma, Chanchal; Jung, Un Ju; Kim, Sehwan; Nam, Youngpyo; Kim, Kyung-Suk; Suk, Kyoungho; Lee, Ho-Won; Kim, Sang Ryong | Kyungpook Natl Univ, Sch Life Sci, Daegu 41566, South Korea; Kyungpook Natl Univ, FOUR KNU Creat Biores Grp BK21, Daegu 41566, South Korea; Pukyong Natl Univ, Dept Food Sci & Nutr, Busan 48513, South Korea; Kyungpook Natl Univ, Brain Sci & Engn Inst, Daegu 41404, South Korea; Corestem Inc, Bioengn Inst, Seoul 13486, South Korea; Kyungpook Natl Univ, Sch Med, Dept Pharmacol, Daegu 41944, South Korea; Kyungpook Natl Univ Chilgok Hosp, Dept Neurol, Daegu 41404, South Korea | 24492053700; 57193577728; 7007119425; 57193232250; 55143100300; 59082232900; 7005114595; 35337240700; 56486163800 | srk75@knu.ac.kr; | JOURNAL OF CLINICAL MEDICINE | J CLIN MED | 2077-0383 | 12 | 5 | SCIE | MEDICINE, GENERAL & INTERNAL | 2023 | 3 | 17.8 | 0.51 | 2025-06-25 | 2 | 2 | human mesenchymal stem cells; cytosine arabinoside; cerebellar ataxia; motor behavior; neurotrophic factor | SPINOCEREBELLAR ATAXIA; STROMAL CELLS; SURVIVAL; PATHOLOGY; SECRETOME; TOXICITY; THERAPY; PROTECT; FETAL | cerebellar ataxia; cytosine arabinoside; human mesenchymal stem cells; motor behavior; neurotrophic factor | calbindin; cytarabine; glial cell line derived neurotrophic factor; inducible nitric oxide synthase; interleukin 1beta; neurotrophic factor; tumor necrosis factor; animal cell; animal experiment; animal model; Article; cell damage; cerebellar ataxia; cerebellum granular layer; controlled study; granule cell; implantation; inflammation; locomotion; male; mesenchymal stem cell transplantation; motor coordination; motor dysfunction; mouse; nerve cell; nonhuman; open field test; protein expression; Purkinje cell; rotarod test; scoring system; therapy effect | English | 2023 | 2023-03 | 10.3390/jcm12051756 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |||
| ○ | ○ | Article | Minimally Invasive Derotational Osteotomy of Long Bones: Smartphone Application Used to Improve the Accuracy of Correction | Correction of rotational malalignments caused by fractures is essential as it may cause pain and gait disturbances. This study evaluated the intraoperative use of a smartphone application (SP app) to measure the extent of corrective rotation in patients treated using minimally invasive derotational osteotomy. Intraoperatively, two parallel 5 mm Schanz pins were placed above and below the fractured/injured site, and derotation was performed manually after percutaneous osteotomy. A protractor SP app was used intraoperatively to measure the angle between the two Schanz pins (angle-SP). Intramedullary nailing or minimally invasive plate osteosynthesis was performed after derotation, and computerized tomography (CT) scans were used to assess the angle of correction postoperatively (angle-CT). The accuracy of rotational correction was assessed by comparing angle-SP and angle-CT. The mean preoperative rotational difference observed was 22.1 degrees, while the mean angle-SP and angle-CT were 21.6 degrees and 21.3 degrees, respectively. A significant positive correlation between angle-SP and angle-CT was observed, and 18 out of 19 patients exhibited complete healing within 17.7 weeks (1 patient exhibited nonunion). These findings suggest that using an SP app during minimally invasive derotational osteotomy can result in accurate correction of malrotation of long bones in a reproducible manner. Therefore, SP technology with integrated gyroscope function represents a suitable alternative for determination of the magnitude of rotational correction when performing corrective osteotomy. | Oh, Chang-Wug; Park, Kyeong-Hyeon; Kim, Joon-Woo; Kim, Dong-Hyun; Seo, Il; Lee, Jin-Han; Kim, Ji-Wan; Yoon, Sung-Hyuk | Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Orthoped Surg, Daegu 41944, South Korea; Yonsei Univ, Severance Childrens Hosp, Dept Orthoped Surg, Coll Med, Seoul 03722, South Korea; Univ Ulsan, Asan Med Ctr, Dept Orthoped Surg, Coll Med, Seoul 05505, South Korea | ; Oh, Chang-Wug/AAO-4602-2021; Park, KyeongHyeon/KEH-4919-2024 | 22135834200; 56969984400; 22951329000; 57198637188; 57192424731; 57202149598; 55898554400; 56323207000 | pkh1112@gmail.com; | JOURNAL OF CLINICAL MEDICINE | J CLIN MED | 2077-0383 | 12 | 4 | SCIE | MEDICINE, GENERAL & INTERNAL | 2023 | 3 | 17.8 | 0.26 | 2025-06-25 | 0 | 1 | derotational osteotomy; malrotation; rotational malalignment; smartphone application | DIAMETER DIFFERENCE SIGN; ROTATIONAL MALALIGNMENT; PLATE OSTEOSYNTHESIS; SHAFT FRACTURES; CORTICAL STEP; MALROTATION; NAVIGATION; AGREEMENT | derotational osteotomy; malrotation; rotational malalignment; smartphone application | adolescent; adult; aged; Article; bone graft; bone radiography; child; clinical article; computer assisted tomography; female; femoral derotation osteotomy; femur shaft fracture; fracture healing; fracture nonunion; human; intramedullary nailing; intraoperative period; long bone; male; measurement accuracy; medical device complication; middle aged; minimally invasive surgery; plate fixation; postoperative care; postoperative period; preoperative evaluation; school child; surgical technique; tibia shaft fracture; varus deformity; young adult | English | 2023 | 2023-02 | 10.3390/jcm12041335 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Moral Distress Regarding End-of-Life Care Among Healthcare Personnel in Korean University Hospitals: Features and Differences Between Physicians and Nurses | Background: Healthcare professionals often experience moral distress while providing end -of-life care. This study explored how physicians and nurses experienced moral distress when they cared for critically and terminally ill patients in tertiary hospitals in South Korea.Methods: This study used semi-structured in-depth interviews. A total of 22 people in two tertiary hospitals were interviewed, nine (40.9%) of which were physicians and 13 (59.1%) were nurses. The recorded interview files and memos were analyzed using grounded theory. Results: Most physicians and nurses encountered similar feelings of anger, helplessness, and burden owing to a lack of appropriate resources for end-of-life care. However, the factors and contexts of their moral distress differed. Nurses mainly addressed poorly organized end-of-life care, intensive labor conditions without support for nurses, and providing care without participation in decision-making. Meanwhile, physicians addressed the prevailing misperceptions on end-of-life care, communication failure between physicians owing to hierarchy and fragmented disciplines, the burden of responsibility in making difficult decisions, and the burden of resource allocation.Conclusion: Differences in moral distress between physicians and nurses leave them isolated and can affect communication regarding healthcare. Mutual understanding between job disciplines will enhance their communication and help resolve conflicts in end-of-life care. | Choi, Eun Kyung; Kang, Jiyeon; Park, Hye Youn; Kim, Yu Jung; Hong, Jinui; Yoo, Shin Hye; Kim, Min Sun; Keam, Bhumsuk; Park, Hye Yoon | Kyungpook Natl Univ, Sch Med, Dept Med Humanities & Med Educ, Daegu, South Korea; Seoul Natl Univ, Dept Anthropol, Seoul, South Korea; Seoul Natl Univ, Dept Psychiat, Coll Med, Seoul, South Korea; Seoul Natl Univ, Bundang Hosp, Dept Internal Med, Coll Med, Seongnam, South Korea; Seoul Natl Univ Hosp, Ctr Palliat Care & Clin Eth, Seoul, South Korea; Seoul Natl Univ, Seoul Natl Univ Hosp, Dept Pediat, Coll Med, Seoul, South Korea; Seoul Natl Univ, Seoul Natl Univ Hosp, Dept Internal Med, Coll Med, Seoul, South Korea; Seoul Natl Univ, Seoul Natl Univ Hosp, Dept Psychiat, Coll Med, 101 Daehak Ro, Seoul 03080, South Korea | Kim, Seonghwan/AAZ-1679-2021; choi, eunkyung/JUF-8150-2023; Kim, Tae-Hee/AAN-9079-2021; Kang, Jiyeon/KHV-4892-2024 | 57391706800; 57217126239; 55794207700; 55694249900; 57218180864; 57192955525; 55568531722; 14028521700; 57189505933 | hypark@snu.ac.kr; | JOURNAL OF KOREAN MEDICAL SCIENCE | J KOREAN MED SCI | 1011-8934 | 1598-6357 | 38 | 22 | SCIE | MEDICINE, GENERAL & INTERNAL | 2023 | 3 | 17.8 | 1.28 | 2025-06-25 | 7 | 5 | End-of-Life Care; Physician-Nurse Relations; Hospitals; Moral Distress; Qualitative Research | PERCEPTIONS; DOCTORS; ETHICS | End-of-Life Care; Hospitals; Moral Distress; Physician-Nurse Relations; Qualitative Research | Attitude of Health Personnel; Hospitals, University; Humans; Morals; Nurses; Physicians; Stress, Psychological; Surveys and Questionnaires; Terminal Care; health personnel attitude; human; mental stress; morality; nurse; physician; questionnaire; terminal care; university hospital | English | 2023 | 2023-06-05 | 10.3346/jkms.2023.38.e169 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Nuclear Factor Erythroid 2-Related Factor 2/Kelch-Like ECH-Associated Protein 1 as a Predictor of Prognosis and Radiotherapy Resistance in Patients With Locally Advanced Rectal Cancer: A Prospective Analysis | Background: The nuclear factor erythroid 2-related factor 2/Kelch-like ECH-associated protein 1 (Nrf2/Keap1) signaling pathway is involved in the regulation of cellular responses to oxidative stress. Nrf2 acts as a cell protector from inflammation, cellular damage, and tumorigenesis, whereas Keap1 is a negative regulator of Nrf2. Dysregulation of the Nrf2/ Keap1 pathway results in tumorigenesis and the active metabolism of tumor cells, leading to high resistance to radiotherapy. This study aimed to evaluate the predictive role of Nrf2 and Keap1 in the radiosensitivity and prognosis of locally advanced rectal cancer (LARC).Methods: In total, 90 patients with LARC underwent surgery after preoperative chemoradiotherapy (CRT). Endoscopic biopsies from the tumors were obtained before radiation, and the Nrf2 and Keap1 expressions were assessed by immunohistochemistry. The response to therapy was evaluated after surgery following CRT according to the pathologic tumor regression grade. The disease-free survival (DFS) and overall survival rates were also documented. The association between the Nrf2 and Keap1 immunoreactivity and the clinicopathological parameters was analyzed.Results: The overexpression of the nuclear Nrf2 before CRT showed a significant correlation with better DFS. The cytoplasmic Nrf2 expression was associated with more residual tumors after radiotherapy and a more unfavorable DFS, indicating lower radiosensitivity.Conclusion: CRT is an important issue in LARC and is a major aspect of treatment. Thus, the Nrf2/Keap1 expression may be a potential predictor of preoperative therapeutic resistance. The Nrf2-Keap1 modulators that interact with each other may also be effectively applicable to CRT effect in LARC. | Park, Ji Min; Kim, Shin; Bae, Sung Uk; Byun, Sang Jun; Seo, Incheol; Lee, Hye Won | Keimyung Univ, Dept Pathol, Dongsan Hosp, Daegu, South Korea; Keimyung Univ, Dept Immunol, Sch Med, Daegu, South Korea; Keimyung Univ, Inst Med Sci, Daegu, South Korea; Keimyung Univ, Inst Canc Res, Daegu, South Korea; Keimyung Univ, Dept Surg, Dongsan Hosp, Daegu, South Korea; Keimyung Univ, Dept Radiat Oncol, Sch Med, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Immunol, 680 Gukchaebosang Ro, Daegu 41944, South Korea; Keimyung Univ, Dept Pathol, Sch Med, 1095 Dalgubeol Daero, Daegu 42601, South Korea | Kim, Shin/D-1669-2013; Bae, Sung/W-1915-2019 | 57223915593; 57210866288; 55748167300; 55446661100; 56022683900; 57907713300 | htr@daum.net;hwlee@dsmc.or.kr; | JOURNAL OF KOREAN MEDICAL SCIENCE | J KOREAN MED SCI | 1011-8934 | 1598-6357 | 38 | 26 | SCIE | MEDICINE, GENERAL & INTERNAL | 2023 | 3 | 17.8 | 0 | 2025-06-25 | 0 | 0 | Rectal Cancer; Radiation Therapy; Tumor Regression; Nrf2; Keap1 | NRF2 | Keap1; Nrf2; Radiation Therapy; Rectal Cancer; Tumor Regression | Carcinogenesis; Humans; Kelch-Like ECH-Associated Protein 1; NF-E2-Related Factor 2; Prognosis; Rectal Neoplasms; kelch like ECH associated protein 1; transcription factor Nrf2; carcinogenesis; human; metabolism; prognosis; rectum tumor | English | 2023 | 2023-07-03 | 10.3346/jkms.2023.38.e200 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Predictors of Extraprostatic Extension in Patients with Prostate Cancer | Purpose: To identify effective factors predicting extraprostatic extension (EPE) in patients with prostate cancer (PCa). Methods: This retrospective cohort study recruited 898 consecutive patients with PCa treated with robot-assisted laparoscopic radical prostatectomy. The patients were divided into EPE and non-EPE groups based on the analysis of whole-mount histopathologic sections. Histopathological analysis (ISUP biopsy grade group) and magnetic resonance imaging (MRI) (PI-RADS v2.1 scores [1-5] and the Mehralivand EPE grade [0-3]) were used to assess the prediction of EPE. We also assessed the clinical usefulness of the prediction model based on decision-curve analysis. Results: Of 800 included patients, 235 (29.3%) had EPE, and 565 patients (70.7%) did not (non-EPE). Multivariable logistic regression analysis showed that the biopsy ISUP grade, PI-RADS v2.1 score, and Mehralivand EPE grade were independent risk factors for EPE. In the regression assessment of the models, the best discrimination (area under the curve of 0.879) was obtained using the basic model (age, serum PSA, prostate volume at MRI, positive biopsy core, clinical T stage, and D'Amico risk group) and Mehralivand EPE grade 3. Decision-curve analysis showed that combining Mehralivand EPE grade 3 with the basic model resulted in superior net benefits for predicting EPE. Conclusion: Mehralivand EPE grades and PI-RADS v2.1 scores, in addition to basic clinical and demographic information, are potentially useful for predicting EPE in patients with PCa. | Kim, See Hyung; Cho, Seung Hyun; Kim, Won Hwa; Kim, Hye Jung; Park, Jong Min; Kim, Gab Chul; Ryeom, Hun Kyu; Yoon, Yu Sung; Cha, Jung Guen | Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Radiol, Daegu 41944, South Korea; Kyungpook Natl Univ, Kyungpook Natl Univ Chilgok Hosp, Sch Med, Dept Radiol, Daegu 41404, South Korea | Kim, Sang-Hyun/J-5402-2012 | 57216511386; 55686242700; 36081886500; 57203506201; 57216463879; 23004499400; 6505864513; 57414392900; 57206855971 | ircha7527@gmail.com; | JOURNAL OF CLINICAL MEDICINE | J CLIN MED | 2077-0383 | 12 | 16 | SCIE | MEDICINE, GENERAL & INTERNAL | 2023 | 3 | 17.8 | 1.02 | 2025-06-25 | 4 | 4 | prostate cancer; extraprostatic extension; magnetic resonance imaging | EXTRACAPSULAR EXTENSION; MULTIPARAMETRIC MRI; RADICAL PROSTATECTOMY; CAPSULAR CONTACT; ACCURACY; LENGTH; SOCIETY; MEN | extraprostatic extension; magnetic resonance imaging; prostate cancer | prostate specific antigen; adult; age; aged; Article; cancer grading; cancer staging; cohort analysis; controlled study; extraprostatic extension; histopathology; human; human tissue; major clinical study; male; malignant neoplasm; nuclear magnetic resonance imaging; prostate cancer; prostate imaging reporting and data system; prostate volume; retrospective study; robot-assisted prostatectomy | English | 2023 | 2023-08 | 10.3390/jcm12165321 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Prevalence of Loneliness and Its Association With Suicidality in the General Population: Results From a Nationwide Survey in Korea | Background: Although it is known that a substantial proportion of the population experience loneliness, the consequence of loneliness remains unclear by countries and ages. Accordingly, this study aimed to assess the association between loneliness and suicidality in the general population of Korea.Method: A total of 5,511 Koreans aged 18-79 completed a tablet-assisted personal interview using the Korean version of the Composite International Diagnostic Interview and responded to questions about loneliness and lifetime suicidal ideation, plans, and attempts. A logistic regression analysis was used to examine the association between loneliness and suicidality.Results: Approximately one-third of the Korean general population reported loneliness. Being older, never married, widowed, separated, or divorced, unemployed, and having a parttime job were all significantly related to loneliness. After adjusting for sociodemographic factors, individuals with loneliness were significantly associated with increased suicidal ideation (adjusted odd ratio [aOR], 4.05; 95% confidence interval [CI], 3.36-4.88), suicidal plans (aOR, 4.91; 95% CI, 3.34-7.21), and suicidal attempts (aOR, 4.82; 95% CI, 3.03-7.66). Even after adjusting for sociodemographic factors and mental disorders, suicidality remained statistically significant. Moreover, frequent, moderate-to-severe, and long-term loneliness were all associated with increased ORs for suicidality, regardless of sociodemographic factors and mental disorders.Conclusion: Loneliness was associated with suicidal ideation, plans, and attempts. This study lays the foundation for public health policymakers to establish early intervention and mental health care support for lonely people. | Lee, Jimin; Chang, Sung Man; Hahm, Bong-Jin; Park, Jee Eun; Seong, Su Jeong; Hong, Jin Pyo; Jeon, Hong Jin; An, Hyonggin; Kim, Byung-Soo | Kyungpook Natl Univ, Sch Med, Dept Psychiat, Daegu, South Korea; Kyungpook Natl Univ Hosp, Dept Psychiat, Daegu, South Korea; Seoul Natl Univ, Coll Med, Dept Psychiat & Behav Sci, Seoul, South Korea; Seoul Natl Univ, Seoul Natl Univ Hosp, Coll Med, Dept Psychiat, Seoul, South Korea; Kangdong Sacred Heart Hosp, Dept Psychiat, Seoul, South Korea; Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Psychiat, Seoul, South Korea; Sungkyunkwan Univ, Dept Psychiat, Depress Ctr, Samsung Med Ctr,Sch Med, Seoul, South Korea; Korea Univ, Dept Biostat, Coll Med, Seoul, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Dept Psychiat, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Psychiat, 680 Gukchaebosang Ro, Daegu 41944, South Korea | ; Hahm, Bong-Jin/J-5714-2012; Kim, Byung-Soo/H-4047-2013 | 57219156372; 23092756400; 6601908426; 56119414400; 55079714000; 55729426400; 35195917400; 7202277445; 57214661242 | because99@hanmail.net; | JOURNAL OF KOREAN MEDICAL SCIENCE | J KOREAN MED SCI | 1011-8934 | 1598-6357 | 38 | 36 | SCIE | MEDICINE, GENERAL & INTERNAL | 2023 | 3 | 17.8 | 1.02 | 2025-06-25 | 4 | 4 | Loneliness; Prevalence; Suicide; Korea; Epidemiology | GENDER | Epidemiology; Korea; Loneliness; Prevalence; Suicide | Humans; Loneliness; Prevalence; Republic of Korea; Suicidal Ideation; Suicide; epidemiology; human; loneliness; prevalence; South Korea; suicidal ideation; suicide | English | 2023 | 2023-09-11 | 10.3346/jkms.2023.38.e287 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Promoter-Specific Variants in NeuroD1 and H3K4me3 Coincident Regions and Clinical Outcomes of Small Cell Lung Cancer | Background: Neurogenic differentiation 1 (NeuroD1) is a representative small cell lung cancer (SCLC) transcription regulator involved in the carcinogenesis and behavior of SCLC. Histone modifications play an important role in transcription, and H3 lysine 4 trimethylation (H3K4me3) is primarily associated with promoter regions. Methods: We investigated the association between single nucleotide polymorphisms (SNPs) in NeuroD1 and H3K4me3 coincident regions, selected using ChIP sequencing (ChIP-seq), and the clinical outcomes of 261 patients with SCLC. Results: Among 230 SNPs, two were significantly associated with both the chemotherapy response and overall survival (OS) of patients with SCLC. RNF145 rs2043268A>G was associated with worse chemotherapy response and OS (under a recessive model, adjusted odds ratio [aOR], 0.50, 95% confidence interval [CI], 0.26-0.94, P = 0.031, and adjusted hazard ratio [aHR], 1.88, 95% CI, 1.38-2.57, P G was also associated with worse chemotherapy response and OS (under a dominant model, aOR, 0.47, 95% CI, 0.23-0.99, P = 0.046, and aHR, 2.03, 95% CI, 1.47-2.82, P G and CINP rs762105A>G were associated with clinical outcomes in patients with SCLC and also affected the promoter activity of each gene. | Yoo, Seung Soo; Lee, Sunwoong; Choi, Jin Eun; Hong, Mi Jeong; Do, Sook Kyung; Lee, Jang Hyuck; Lee, Won Kee; Park, Ji Eun; Ha Choi, Sun; Seo, Hyewon; Lee, Jaehee; Cha, Seung Ick; Kim, Chang Ho; Kang, Hyo-Gyoung; Park, Jae Yong | Kyungpook Natl Univ, Sch Med, Dept Internal Med, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Biochem & Cell Biol, Daegu, South Korea; Kyungpook Natl Univ, Dept Biomed Sci, BK21 Plus KNU Biomed Convergence Program, Daegu, South Korea; Kyungpook Natl Univ, Cell & Matrix Res Inst, Sch Med, Daegu, South Korea; Kyungpook Natl Univ Hosp, Med Res Collaborat Ctr, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Daegu, South Korea; Kyungpook Natl Univ, Cell & Matrix Res Inst, Sch Med, 680 Gukchaebosang Ro, Daegu 41944, South Korea; Kyungpook Natl Univ, Chilgok Hosp, Lung Canc Ctr, 807 Hoguk Ro, Daegu 41404, South Korea | ; Park, Jinkyeong/GLV-1649-2022; Lee, Yoojin/AAB-9799-2022; Lee, Jaehee/S-1697-2018 | 56479781600; 57939037100; 37107028100; 55613917100; 56333658000; 57161223200; 22953484700; 57195437358; 57199022948; 57199723585; 55612130200; 13805476000; 49863712700; 35227126400; 7409873555; 8573181300; 58360293800 | pearlblue0@gmail.com;jaeyong@knu.ac.kr; | JOURNAL OF KOREAN MEDICAL SCIENCE | J KOREAN MED SCI | 1011-8934 | 1598-6357 | 38 | 45 | SCIE | MEDICINE, GENERAL & INTERNAL | 2023 | 3 | 17.8 | 0.51 | 2025-06-25 | 2 | 2 | NeuroD1; Small Cell Lung Cancer; Variant; ChIP-seq | GENOTYPING CONCORDANCE; BREAST-CANCER; STATIN USE; TUMOR; DNA; MORTALITY; POLYMORPHISMS; METAANALYSIS; PROGRESSION; RECURRENCE | ChIP-seq; H3K4me3; NeuroD1; Small Cell Lung Cancer; Variant | Histones; Humans; Lung Neoplasms; Promoter Regions, Genetic; Small Cell Lung Carcinoma; lysine; neurogenic differentiation factor; adult; article; chromatin immunoprecipitation; chromatin immunoprecipitation sequencing; clinical outcome; controlled study; drug therapy; female; gene expression; histone modification; human; human cell; human tissue; luciferase assay; male; overall survival; promoter region; real time polymerase chain reaction; single nucleotide polymorphism; small cell lung cancer | English | 2023 | 2023-11-20 | 10.3346/jkms.2023.38.e381 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | |
| ○ | ○ | Article | Prophylactic Femoral Neck Fixation in an Osteoporosis Femur Model: A Novel Surgical Technique with Biomechanical Study | Intramedullary nailing (IMN) is a popular treatment for elderly patients with femoral shaft fractures. Recently, prophylactic neck fixation has been increasingly used to prevent proximal femoral fractures during IMN. Therefore, this study aimed to investigate the biomechanical strength of prophylactic neck fixation in osteoporotic femoral fractures. An osteoporotic femur model was created to simulate the union of femoral shaft fractures with IMN. Two study groups comprising six specimens each were created for IMN with two standard proximal locking screws (SN group) and IMN with two reconstruction proximal locking screws (RN group). Axial loading was conducted to measure the stiffness, load-to-failure, and failure modes. There were no statistically significant differences in stiffness between the two groups. However, the load-to-failure in the RN group was significantly higher than that in the SN group (p < 0.05). Femoral neck fractures occurred in all specimens in the SN group. Five constructs in the RN group showed subtrochanteric fractures without femoral neck fractures. However, one construct was observed in both subtrochanteric and femoral neck fractures. Therefore, prophylactic neck fixation may be considered an alternative biomechanical solution to prevent proximal femoral fractures when performing IMN for osteoporotic femoral fractures. | Park, Kyeong-Hyeon; Oh, Chang-Wug; Kim, Joon-Woo; Kim, Hee-Jun; Kim, Dong-Hyun; Lee, Jin-Han; Hong, Won-Ki; Oh, Jong-Keon | Kyungpook Natl Univ, Kyungpook Natl Univ Hosp, Sch Med, Dept Orthoped Surg, Daegu 41944, South Korea; Korea Univ, Sch Med, Dept Orthoped Surg, Guro Hosp, Seoul 10408, South Korea | Park, KyeongHyeon/KEH-4919-2024; Kim, Jung-Ae/B-1389-2013; Oh, Chang-Wug/AAO-4602-2021 | 56969984400; 22135834200; 22951329000; 58479852000; 57198637188; 57202149598; 57218322356; 7402155046 | cwoh@knu.ac.kr; | JOURNAL OF CLINICAL MEDICINE | J CLIN MED | 2077-0383 | 12 | 1 | SCIE | MEDICINE, GENERAL & INTERNAL | 2023 | 3 | 17.8 | 0.77 | 2025-06-25 | 1 | 3 | femur; nail; osteoporosis; prophylaxis | INTRAMEDULLARY NAIL; SHAFT FRACTURES; ENTRY | femur; nail; osteoporosis; prophylaxis | Article; axial loading; biomechanics; bone radiography; compressive strength; failure load; failure mode; femoral neck fracture; femur shaft fracture; femur subtrochanteric fracture; fragility fracture; greater trochanter; intramedullary nailing; load to failure; prophylactic femoral neck fixation; rigidity; simulation; surgical technique | English | 2023 | 2023-01 | 10.3390/jcm12010383 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Regional Disparities in the Infant Mortality Rate in Korea Between 2001 and 2021 | Background: The infant mortality rate (IMR) has been considered an important indicator of the overall public health level. Despite improvements in recent decades, regional inequalities in the IMR have been reported worldwide. However, there are no Korean epidemiological studies on regional disparities in the IMR. Methods: We extracted causes of death data from the Statistics Korea through the Korean Statistical Information Service database between 2001 and 2021. The total and regional IMRs were calculated to determine regional disparities. Based on causes of death and using Seoul as a reference, the excess infant deaths and population attributable fractions (PAFs) were calculated for 15 other metropolitan cities and provinces. The average annual percent changes by region from 2001 to 2021 were obtained using a joinpoint regression program. To assess inequities in IMR trends, the rate ratios (RRs) and rate differences (RDs) of the 15 regions were calculated by dividing the study period into period 1 (2001-2007), period 2 (2008-2014), and period 3 (2015-2021). Results: The overall IMR in Korea was 3.64 per 1,000 live births, and the IMRs in the 14 regions were relatively higher than that in Seoul, with RRs ranging from 1.15 (95% confidence interval [CI], 1.04, 1.27) in Jeju-do to 1.62 (95% CI, 1.54, 1.71) in Daegu, over the total study period. Significant differences in infant deaths by region were observed for all causes of death, with PAFs ranging from 2.2% (95% CI, 1.7, 2.6) in Gyeonggi-do to 38.4% (95% CI, 38.1, 38.6) in Daegu. The leading cause of excess infant deaths was perinatal problems. The IMR disparities in the relative and absolute measures decreased from 1.44 (1.34, 1.54) to 1.21 (1.10, 1.31) for RRs and from 0.79 (0.63, 0.96) to 0.30 (0.15, 0.45) for RDs between periods 1 and 2, followed by an increase from 1.21 (1.10, 1.31) to 1.36 (1.21, 1.53) for RRs and from 0.30 (0.15, 0.45) to 0.51(0.36, 0.67) for RDs between period 2 and 3. Conclusion: Infant death is associated with place of residence and regional gaps have recently widened again in Korea. An in-depth investigation of the causes of regional disparities in infant mortality is required for effective governmental policies to achieve equality in infant health. | Woo, Hyeongtaek; Kim, Ji Sook | Keimyung Univ, Sch Med, Dept Prevent Med, Daegu, South Korea; Kyungpook Natl Univ, Sch Med, Dept Pediat, 807 Hoguk Ro, Daegu 41404, South Korea | 57061743800; 57194705685 | jisook.kim.neo@gmail.com; | JOURNAL OF KOREAN MEDICAL SCIENCE | J KOREAN MED SCI | 1011-8934 | 1598-6357 | 38 | 44 | SCIE | MEDICINE, GENERAL & INTERNAL | 2023 | 3 | 17.8 | 0.51 | 2025-06-25 | 2 | 2 | Infant Mortality; Child Mortality; Health Inequities; Korea | LOW-BIRTH-WEIGHT; PERINATAL-MORTALITY; NEONATAL-MORTALITY; INTENSIVE-CARE; TRENDS; ASSOCIATION; OUTCOMES; IMPACT; INCOME; JAPAN | Child Mortality; Health Inequities; Infant Mortality; Korea | Female; Humans; Infant; Infant Death; Infant Mortality; Parturition; Pregnancy; Public Health; Seoul; birth; child death; female; human; infant; infant mortality; pregnancy; public health; South Korea | English | 2023 | 2023-11-13 | 10.3346/jkms.2023.38.e367 | 바로가기 | 바로가기 | 바로가기 | 바로가기 | ||
| ○ | ○ | Article | Seasonal Trends in the Prevalence and Incidence of Viral Encephalitis in Korea (2015-2019) | Viral infections are a common cause of encephalitis. This study investigated the relationship between the incidence of encephalitis and that of respiratory and enteric viral infections in all age groups from 2015 to 2019, using the Health Insurance Review and Assessment (HIRA) Open Access Big Data Platform. We identified monthly incidence patterns and seasonal trends using the autoregressive integrated moving average (ARIMA). The Granger causality test was used to analyze correlations between encephalitis incidence and the positive detection rate (PDR) at 1-month intervals. A total of 42,775 patients were diagnosed with encephalitis during the study period. The incidence of encephalitis was highest in the winter (26.8%). The PDRs for respiratory syncytial virus (HRSV) and coronavirus (HCoV) were associated with the trend in encephalitis diagnosis in all age groups, with a 1-month lag period. In addition, an association with norovirus was observed in patients aged over 20 years, and with influenza virus (IFV) in patients aged over 60 years. This study found that HRSV, HCoV, IFV, and norovirus tended to precede encephalitis by 1 month. Further research is required to confirm the association between these viruses and encephalitis. | Lee, Seon Jin; Kim, Jeong Min; Keum, Ha Rim; Kim, Sang Won; Baek, Hee Sun; Byun, Jun Chul; Kim, Yu Kyung; Kim, Saeyoon; Lee, Jae Min | Yeungnam Univ, Coll Med, Dept Med, Daegu 42415, South Korea; Yeungnam Univ, Coll Med, Med Res Ctr, Daegu 42415, South Korea; Yeungnam Univ, Coll Med, Dept Pediat, Daegu 42415, South Korea; Keimyung Univ, Sch Med, Dept Pediat, Daegu 42601, South Korea; Kyungpook Natl Univ, Sch Med, Dept Clin Pathol, Daegu 41944, South Korea | ; Lee, Jae Min/H-8475-2013 | 58134148300; 58134750400; 58134750500; 57219871166; 56689379700; 55671798400; 9237571900; 53984438900; 39261799700 | sysnow88@hanmail.net;mopic@yu.ac.kr; | JOURNAL OF CLINICAL MEDICINE | J CLIN MED | 2077-0383 | 12 | 5 | SCIE | MEDICINE, GENERAL & INTERNAL | 2023 | 3 | 17.8 | 1.54 | 2025-06-25 | 6 | 6 | encephalitis; respiratory syncytial virus; coronavirus; influenza virus; norovirus | HUMAN METAPNEUMOVIRUS; CEREBROSPINAL-FLUID; UNITED-STATES; NEUROLOGIC COMPLICATIONS; HUMAN BOCAVIRUS; CHILDREN; EPIDEMIOLOGY; ENCEPHALOPATHY; INFLUENZA; INFECTION | coronavirus; encephalitis; influenza virus; norovirus; respiratory syncytial virus | adolescent; adult; Article; autumn; causality; child; Coronaviridae; Coronavirinae; correlation analysis; cumulative incidence; female; groups by age; human; Human adenovirus C; Human bocavirus; Human metapneumovirus; Human respiratory syncytial virus; Human rhinovirus; incidence; infant; Influenza virus; Korea; major clinical study; male; newborn; nonhuman; Norovirus; Paramyxovirinae; prevalence; seasonal variation; spring; summer; trend study; virus encephalitis; winter | English | 2023 | 2023-03 | 10.3390/jcm12052003 | 바로가기 | 바로가기 | 바로가기 | 바로가기 |
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